Search of human proteins with 210147462

Search of human proteins with 210147462

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|210147462 von Willebrand factor A domain containing 5B1
[Homo sapiens]
         (1215 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|210147462 von Willebrand factor A domain containing 5B1 [Homo...  2453   0.0  
gi|222352129 von Willebrand factor A domain containing 5B2 [Homo...   532   e-151
gi|194306644 BCSC-1 isoform 1 [Homo sapiens]                          225   2e-58
gi|38195080 BCSC-1 isoform 1 [Homo sapiens]                           225   2e-58
gi|38195082 BCSC-1 isoform 2 [Homo sapiens]                           164   5e-40
gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo...   105   2e-22
gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor ...    68   6e-11
gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor...    68   6e-11
gi|153945711 inter-alpha trypsin inhibitor heavy chain precursor...    68   6e-11
gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens]        63   1e-09
gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens]         55   4e-07
gi|70778918 inter-alpha globulin inhibitor H2 polypeptide [Homo ...    47   8e-05
gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein [...    47   8e-05
gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens]    46   2e-04
gi|26051231 lactamase, beta isoform a [Homo sapiens]                   43   0.002
gi|26051233 lactamase, beta isoform b [Homo sapiens]                   43   0.002
gi|5031855 lymphocyte cytosolic protein 2 [Homo sapiens]               40   0.018
gi|197333868 T-box 2 [Homo sapiens]                                    38   0.067
gi|95147555 microtubule-associated protein 1A [Homo sapiens]           37   0.11 
gi|126362971 serine/threonine kinase 10 [Homo sapiens]                 36   0.20 
gi|156616290 collagen type VI alpha 6 [Homo sapiens]                   36   0.25 
gi|31581524 cordon-bleu homolog [Homo sapiens]                         35   0.43 
gi|150417978 platelet glycoprotein Ib alpha polypeptide precurso...    35   0.57 
gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]              34   0.74 
gi|21237808 SWI/SNF-related matrix-associated actin-dependent re...    34   0.74 
gi|148762963 armadillo repeat containing 2 [Homo sapiens]              34   0.97 
gi|4502131 amyloid beta A4 precursor protein-binding, family B, ...    33   1.3  
gi|22035554 amyloid beta A4 precursor protein-binding, family B,...    33   1.3  
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    33   1.3  
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]     33   1.3  

>gi|210147462 von Willebrand factor A domain containing 5B1 [Homo
            sapiens]
          Length = 1215

 Score = 2453 bits (6357), Expect = 0.0
 Identities = 1215/1215 (100%), Positives = 1215/1215 (100%)

Query: 1    MPGLLNWITGAALPLTASDVTSCVSGYALGLTASLTYGNLEAQPFQGLFVYPLDECTTVI 60
            MPGLLNWITGAALPLTASDVTSCVSGYALGLTASLTYGNLEAQPFQGLFVYPLDECTTVI
Sbjct: 1    MPGLLNWITGAALPLTASDVTSCVSGYALGLTASLTYGNLEAQPFQGLFVYPLDECTTVI 60

Query: 61   GFEAVIADRVVTVQIKDKAKLESGHFDASHVRSPTVTGNILQDGVSIAPHSCTPGKVTLD 120
            GFEAVIADRVVTVQIKDKAKLESGHFDASHVRSPTVTGNILQDGVSIAPHSCTPGKVTLD
Sbjct: 61   GFEAVIADRVVTVQIKDKAKLESGHFDASHVRSPTVTGNILQDGVSIAPHSCTPGKVTLD 120

Query: 121  EDLERILFVANLGTIAPMENVTIFISTSSELPTLPSGAVRVLLPAVCAPTVPQFCTKSTG 180
            EDLERILFVANLGTIAPMENVTIFISTSSELPTLPSGAVRVLLPAVCAPTVPQFCTKSTG
Sbjct: 121  EDLERILFVANLGTIAPMENVTIFISTSSELPTLPSGAVRVLLPAVCAPTVPQFCTKSTG 180

Query: 181  TSNQQAQGKDRHCFGAWAPGSWNKLCLATLLNTEVSNPMEYEFNFQLEIRGPCLLAGVES 240
            TSNQQAQGKDRHCFGAWAPGSWNKLCLATLLNTEVSNPMEYEFNFQLEIRGPCLLAGVES
Sbjct: 181  TSNQQAQGKDRHCFGAWAPGSWNKLCLATLLNTEVSNPMEYEFNFQLEIRGPCLLAGVES 240

Query: 241  PTHEIRADAAPSARSAKSIIITLANKHTFDRPVEILIHPSEPHMPHVLIEKGDMTLGEFD 300
            PTHEIRADAAPSARSAKSIIITLANKHTFDRPVEILIHPSEPHMPHVLIEKGDMTLGEFD
Sbjct: 241  PTHEIRADAAPSARSAKSIIITLANKHTFDRPVEILIHPSEPHMPHVLIEKGDMTLGEFD 300

Query: 301  QHLKGRTDFIKGMKKKSRAERKTEIIRKRLHKDIPHHSVIMLNFCPDLQSVQPCLRKAHG 360
            QHLKGRTDFIKGMKKKSRAERKTEIIRKRLHKDIPHHSVIMLNFCPDLQSVQPCLRKAHG
Sbjct: 301  QHLKGRTDFIKGMKKKSRAERKTEIIRKRLHKDIPHHSVIMLNFCPDLQSVQPCLRKAHG 360

Query: 361  EFIFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDS 420
            EFIFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDS
Sbjct: 361  EFIFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDS 420

Query: 421  LAMACDDIQRMKADMGGTNILSPLKWVIRQPVHRGHPRLLFVITDGAVNNTGKVLELVRN 480
            LAMACDDIQRMKADMGGTNILSPLKWVIRQPVHRGHPRLLFVITDGAVNNTGKVLELVRN
Sbjct: 421  LAMACDDIQRMKADMGGTNILSPLKWVIRQPVHRGHPRLLFVITDGAVNNTGKVLELVRN 480

Query: 481  HAFSTRCYSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKSLKKAMAPVLSDV 540
            HAFSTRCYSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKSLKKAMAPVLSDV
Sbjct: 481  HAFSTRCYSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKSLKKAMAPVLSDV 540

Query: 541  TVEWIFPETTEVLVSPVSASSLFPGERLVGYGIVCDASLHISNPRSDKRRRYSMLHSQES 600
            TVEWIFPETTEVLVSPVSASSLFPGERLVGYGIVCDASLHISNPRSDKRRRYSMLHSQES
Sbjct: 541  TVEWIFPETTEVLVSPVSASSLFPGERLVGYGIVCDASLHISNPRSDKRRRYSMLHSQES 600

Query: 601  GSSVFYHSQDDGPGLEGGDCAKNSGAPFILGQAKNARLASGDSTTKHDLNLSQRRRAYST 660
            GSSVFYHSQDDGPGLEGGDCAKNSGAPFILGQAKNARLASGDSTTKHDLNLSQRRRAYST
Sbjct: 601  GSSVFYHSQDDGPGLEGGDCAKNSGAPFILGQAKNARLASGDSTTKHDLNLSQRRRAYST 660

Query: 661  NQITNHKPLPRATMASDPMPAAKRYPLRKARLQDLTNQTSLDVQRWQIDLQPLLNSGQDL 720
            NQITNHKPLPRATMASDPMPAAKRYPLRKARLQDLTNQTSLDVQRWQIDLQPLLNSGQDL
Sbjct: 661  NQITNHKPLPRATMASDPMPAAKRYPLRKARLQDLTNQTSLDVQRWQIDLQPLLNSGQDL 720

Query: 721  NQGPKLRGPGARRPSLLPQGCQPFLPWGQETQAWSPVRERTSDSRSPGDLEPSHHPSAFE 780
            NQGPKLRGPGARRPSLLPQGCQPFLPWGQETQAWSPVRERTSDSRSPGDLEPSHHPSAFE
Sbjct: 721  NQGPKLRGPGARRPSLLPQGCQPFLPWGQETQAWSPVRERTSDSRSPGDLEPSHHPSAFE 780

Query: 781  TETSSDWDPPAESQERASPSRPATPAPVLGKALVKGLHDSQRLQWEVSFELGTPGPERGG 840
            TETSSDWDPPAESQERASPSRPATPAPVLGKALVKGLHDSQRLQWEVSFELGTPGPERGG
Sbjct: 781  TETSSDWDPPAESQERASPSRPATPAPVLGKALVKGLHDSQRLQWEVSFELGTPGPERGG 840

Query: 841  AQDADLWSETFHHLAARAIIRDFEQLAEREGEIEQGSNRRYQVSALHTSKACNIISKYTA 900
            AQDADLWSETFHHLAARAIIRDFEQLAEREGEIEQGSNRRYQVSALHTSKACNIISKYTA
Sbjct: 841  AQDADLWSETFHHLAARAIIRDFEQLAEREGEIEQGSNRRYQVSALHTSKACNIISKYTA 900

Query: 901  FVPVDVSKSRYLPTVVEYPNSGAALRMLGSRALAQQWRGTSSGFGRPQTMLGEDSAPGND 960
            FVPVDVSKSRYLPTVVEYPNSGAALRMLGSRALAQQWRGTSSGFGRPQTMLGEDSAPGND
Sbjct: 901  FVPVDVSKSRYLPTVVEYPNSGAALRMLGSRALAQQWRGTSSGFGRPQTMLGEDSAPGND 960

Query: 961  MEASPTALFSEARSPGREKHGASEGPQRSLATNTLSSMKASENLFGSWLNLNKSRLLTRA 1020
            MEASPTALFSEARSPGREKHGASEGPQRSLATNTLSSMKASENLFGSWLNLNKSRLLTRA
Sbjct: 961  MEASPTALFSEARSPGREKHGASEGPQRSLATNTLSSMKASENLFGSWLNLNKSRLLTRA 1020

Query: 1021 AKGFLSKPLIKAVESTSGNQSFDYIPLVSLQLASGAFLLNEAFCEATHIPMEKLKWTSPF 1080
            AKGFLSKPLIKAVESTSGNQSFDYIPLVSLQLASGAFLLNEAFCEATHIPMEKLKWTSPF
Sbjct: 1021 AKGFLSKPLIKAVESTSGNQSFDYIPLVSLQLASGAFLLNEAFCEATHIPMEKLKWTSPF 1080

Query: 1081 TCHRVSLTTRPSESKTPSPQLCTSSPPRHPSCDSFSLEPLAKGKLGLEPRAVVEHTGKLW 1140
            TCHRVSLTTRPSESKTPSPQLCTSSPPRHPSCDSFSLEPLAKGKLGLEPRAVVEHTGKLW
Sbjct: 1081 TCHRVSLTTRPSESKTPSPQLCTSSPPRHPSCDSFSLEPLAKGKLGLEPRAVVEHTGKLW 1140

Query: 1141 ATVVGLAWLEHSSASYFTEWELVAAKANSWLEQQEVPEGRTQGTLKAAARQLFVLLRHWD 1200
            ATVVGLAWLEHSSASYFTEWELVAAKANSWLEQQEVPEGRTQGTLKAAARQLFVLLRHWD
Sbjct: 1141 ATVVGLAWLEHSSASYFTEWELVAAKANSWLEQQEVPEGRTQGTLKAAARQLFVLLRHWD 1200

Query: 1201 ENLEFNMLCYNPNYV 1215
            ENLEFNMLCYNPNYV
Sbjct: 1201 ENLEFNMLCYNPNYV 1215


>gi|222352129 von Willebrand factor A domain containing 5B2 [Homo
            sapiens]
          Length = 1242

 Score =  532 bits (1371), Expect = e-151
 Identities = 413/1315 (31%), Positives = 610/1315 (46%), Gaps = 179/1315 (13%)

Query: 1    MPGLLNWITGAALPLTASDVTSCVSGYALGLTASLTYGNLEAQPFQGLFVYPLDECTTVI 60
            MPGL    +   LPLT S V +C +G  L + A LTY N + QP  G+FVYPL E   V 
Sbjct: 1    MPGLYCPSSWTPLPLTDSWVRACANGPCLSVRARLTYRNPQPQPVDGVFVYPLAEAEVVS 60

Query: 61   GFEAVIADRVVTVQIKDKAKLESGHFDASHVRSPTVTGNILQDGVSI-APHSCTPGKVTL 119
            GFEA  A R V+ Q++ +             RS       L  G+    P  C  G + L
Sbjct: 61   GFEAEAAGRRVSFQLQSRR------------RSQAACCRALGPGLGTPTPRRCAQGHLVL 108

Query: 120  DEDLERILFVANLGTIAPMENVTIFISTSSELPTLPSGAVRVLLPAVCAPTVPQFCTKST 179
            D    R   V   G IA    +T+ + +S ELP+ P G + V LP V  P  P       
Sbjct: 109  DLAQARSTLVLPTGIIAAAGTMTVTLHSSRELPSRPDGVLHVALPTVLTPLAPP---GPP 165

Query: 180  GTSNQQAQGKDR--HCFGAWAPG----SWNKLCLAT-LLNTEVSNPMEYEFNFQLEIRGP 232
            G         D    CFG  +      +W +L     + +     P  Y F+F++ + GP
Sbjct: 166  GPPRPPGLCDDSPTSCFGVGSLQEEGLAWEELAAPRDVFSGPARCPAPYTFSFEMLVTGP 225

Query: 233  CLLAGVESPTHEIRADAAPSARSAKSIIITLANKHTFDRPVEILIHPSEPHMPHVLIEKG 292
            CLLAG+ESP+H +RADA P A SA +I +TLA  H  DR +EIL+HPSEPH PH+++E G
Sbjct: 226  CLLAGLESPSHALRADAPPHASSAATICVTLAEGHHCDRALEILLHPSEPHQPHLMLEGG 285

Query: 293  DMTLGEFDQHLKGRTDFIKGMKKKSRAERKTEIIRKRLHKDIPHHSVIMLNFCPDLQSVQ 352
             ++  E++  ++ R DF +  ++ S  +R+   +++R HKDI  + V+ L+FCPDL S  
Sbjct: 286  SLSSAEYEARVRARRDFQRLQRRDSDGDRQVWFLQRRFHKDILLNPVLALSFCPDLSSKP 345

Query: 353  PCLRKAHGEFIFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPS 412
              L  A  E +FL+D SS          KDA+++A+KSL P  L N+  FG+  + LFP 
Sbjct: 346  GHLGTATRELLFLLDSSSVAH-------KDAIVLAVKSLPPQTLINLAVFGTLVQPLFPE 398

Query: 413  SQTYSEDSLAMACDDIQRMKADMGGTNILSPLKWVIRQPVHRGHPRLLFVITDGA--VNN 470
            S+  S+D++ + C+ I+ ++   G  ++L+ L W + QP HR +PR LF++T  +     
Sbjct: 399  SRPCSDDAVQLICESIETLQVPSGPPDVLAALDWAVGQPQHRAYPRQLFLLTAASPMAAT 458

Query: 471  TGKVLELVRNHAFSTRCYSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKSLK 530
            T + LEL+R H  + RC+SFG+GP  CH+L++GL+++S G A  L  G+RLQP +V++L+
Sbjct: 459  THRTLELMRWHRGTARCFSFGLGP-TCHQLLQGLSALSRGQAYFLRPGQRLQPMLVQALR 517

Query: 531  KAMAPVLSDVTVEWIFPETTEVLVSPVSASSLFPGERLVGYGIVCDASLHISNPRSDKRR 590
            KA+ P LSD++V+W  P+T E L++P    +L+PG++L+GY  +       S P   +  
Sbjct: 518  KALEPALSDISVDWFVPDTVEALLTPREIPALYPGDQLLGYCSLFRVDGFRSRPPGGQEP 577

Query: 591  RYSMLHSQESGSSVFYHSQDDGPGLEGGDCAKNSGAPFILGQAKNARLASGDSTTKHDLN 650
             +     Q SG SVF   ++          A ++ +P       +  L +G  + +    
Sbjct: 578  GW-----QSSGGSVFPSPEE----------APSAASPGTEPTGTSEPLGTGTVSAELSSP 622

Query: 651  LSQRRRAYSTNQITNHKPLPRATMASDPMPAAKRYPLRKARLQDLTNQTSLDVQRWQIDL 710
             + R    ST+ +T+          +DP P      + +   Q    +    +       
Sbjct: 623  WAARDSEQSTDALTD--------PVTDPGPNPSDTAIWRRIFQSSYIREQYVLTHCSASP 674

Query: 711  QPLLNSGQDLNQGPKLRGPGARRPS--LLP---QGCQPFLPWGQETQAWS-PVRERTSDS 764
            +P   S    ++ P  +GPG+   S  L P   QGC+  L WG+   + S P+   T   
Sbjct: 675  EPGPGS-TGSSESPGSQGPGSPEGSAPLEPPSQQGCRS-LAWGEPAGSRSCPLPAPTPAP 732

Query: 765  RSPGDLEPS----HHPSAFETETSSDWDPPAESQERASPSRPAT------PAPVLGKALV 814
               G L        H +A    + S   P   +Q    P +P+       P+P  G+ L 
Sbjct: 733  FKVGALSTEVLGRQHRAALAGRSLSS-PPGRANQVPGRPRKPSLGAILDGPSPEPGQQLG 791

Query: 815  KGLHDS----------------------------------------------------QR 822
            +GL DS                                                    Q 
Sbjct: 792  QGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQAPRCHVVIRGLCGEQP 851

Query: 823  LQWEVSFELGTPGPERGGAQDAD------LWSETFHHLAARAIIRDFEQLAEREG---EI 873
            + WEV   L T      G+Q          W +  H L A +++RD EQLA R G     
Sbjct: 852  MCWEVGVGLETLWGPGDGSQPPSPPVREAAWDQALHRLTAASVVRDNEQLALRGGAETTA 911

Query: 874  EQGSNRRYQVSALHTSKACNIISKYTAFVPVDVSKSRYLPTVVEYPNSGAALRMLGSRAL 933
            ++G  RR  + AL TSK  +  S +T  V VD +    LP  ++  +S  A         
Sbjct: 912  DRGHARRCWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQVCSSEPA--------- 962

Query: 934  AQQWRGTSSGFGRPQTMLGEDSAPGNDMEASPTALFSEARSPGREKHGASEGPQRSLATN 993
              +  GT      P +    D+AP       PT ++S+    G    GA +  Q   +  
Sbjct: 963  --EPPGTP-----PASHSHLDAAP------LPTVVYSKGLQRG-SPAGAWDSDQNGNSKR 1008

Query: 994  TLSSMKASENLFGSWLNLNKSRLLTRAAKGFLSKPLIKAVESTSGNQSFDYIPLVSLQLA 1053
             L    A+               L+   +  L  P      ++ G+   DY+PLV LQ A
Sbjct: 1009 ALGD-PATPTEGPRRPPPRPPCRLSMGRRHKLCSPDPGQANNSEGS-DHDYLPLVRLQEA 1066

Query: 1054 SGAFLLNEAFCEATHIPMEKLKWTSPFTCHRVSLTTRPSESKTPSPQL---------CTS 1104
             G+F L+  FC A  I  E+L   SPF  HR SL+  P+ +  P   L          T+
Sbjct: 1067 PGSFRLDAPFCAAVRISQERLCRASPFAVHRASLS--PTSASLPWALLGPGVGQGDSATA 1124

Query: 1105 SPPRHPSCDSFSLEPLAKGK-------LGLEPRAVVEHTGKLWATVVGLAWLEHSSASYF 1157
            S    PS  S     +  G+        G E     +  G+ WAT V LAWLEH  A+ F
Sbjct: 1125 SCSPSPSSGSEGPGQVDSGRGSDTEASEGAEGLGGTDLRGRTWATAVALAWLEHRCAAAF 1184

Query: 1158 TEWELVAAKANSWLEQQEVPEGRTQGTLKAAARQLFVLLRHWDENLEFNMLCYNP 1212
             EWEL AAKA+ WL  Q +P+G     LKAAAR LF+LLRHWD+NL+ ++LCY+P
Sbjct: 1185 DEWELTAAKADCWLRAQHLPDGLDLAALKAAARGLFLLLRHWDQNLQLHLLCYSP 1239


>gi|194306644 BCSC-1 isoform 1 [Homo sapiens]
          Length = 786

 Score =  225 bits (574), Expect = 2e-58
 Identities = 168/570 (29%), Positives = 269/570 (47%), Gaps = 95/570 (16%)

Query: 13  LPLTASDVTSCVSGYALGLTASLTYGNLEAQPFQGLFVYPLDECTTVIGFEAVIADRVVT 72
           +PL +  V+  +  +  G++A+L Y N E  P +  FV+P+DE + V  FEA++  + + 
Sbjct: 15  VPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIV 74

Query: 73  VQIKDKAKLESGHFDASHVRSPTVTGNILQDGVSIAPHSCTPGKVTLDEDLERILFVANL 132
            +++DK K  + +  A            L +G S +                R +F  N+
Sbjct: 75  AELQDKMKARTNYEKAISQGHQA----FLLEGDSSS----------------RDVFSCNV 114

Query: 133 GTIAPMENVTIFISTSSELPTLPSGAVRVLLPAVCAPTVPQFCTKSTGTSNQQAQGKDRH 192
           G + P     + +    ELP    GA+R +LPAV  P   QF    +G+S          
Sbjct: 115 GNLQPGSKAAVTLKYVQELPLEADGALRFVLPAVLNPRY-QF----SGSSKDSCLNVKTP 169

Query: 193 CFGAWAPGSWNKLCLATLLNTEVSNPMEYEFNFQLEIRGPCLLAGVESPTHEIRADAAPS 252
                 P       L+ +   +  + +E       +++  C L    SPT  +  D    
Sbjct: 170 I----VPVEDLPYTLSMVATIDSQHGIE-------KVQSNCPL----SPTEYLGEDKT-- 212

Query: 253 ARSAKSIIITLANKHTFDRPVEILIHPSEPHMPHVLIEKG--DMTLGEFDQHLKGRTDFI 310
                S  ++LA  H FDR VE+LI+ +E H P V++E G  +M  G    HL G     
Sbjct: 213 -----SAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPNMKPG----HLMGDPS-- 261

Query: 311 KGMKKKSRAERKTEIIRKRLHKDIPHHSVIMLNFCPDLQSVQPCLRKAHGEFIFLIDRSS 370
                                         M++F P++   QP      GEFIFL+DRS 
Sbjct: 262 -----------------------------AMVSFYPNIPEDQPS--NTCGEFIFLMDRSG 290

Query: 371 SM---------SGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDSL 421
           SM         S + +   K+ +++ LKSL   C FNI GFGS++++ FP S  Y++ ++
Sbjct: 291 SMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTM 350

Query: 422 AMACDDIQRMKADMGGTNILSPLKWVIRQPVHRGHPRLLFVITDGAVNNTGKVLELVRNH 481
             A   ++ M+AD+GGT IL+PL+ + R P   GHP  LFV TDG V +T  V++ VR +
Sbjct: 351 EEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRIN 410

Query: 482 AFSTRCYSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKSLKKAMAPVLSDVT 541
               RC+SFGIG      L+KG+A  S G++E +   +R+Q K +++LK+++ PV+ DV+
Sbjct: 411 RQKHRCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVS 470

Query: 542 VEWIFPETTEVLVSPVSASSLFPGERLVGY 571
           + W  P      +     + +F G+RL+ Y
Sbjct: 471 LSWHLPPGLSAKMLSPEQTVIFRGQRLISY 500



 Score = 37.4 bits (85), Expect = 0.088
 Identities = 15/47 (31%), Positives = 27/47 (57%), Gaps = 2/47 (4%)

Query: 1125 LGLEPRAVVEHTGKLWATVVGLAWLEHSSASYFTEWELVAAKANSWL 1171
            +  +P  +V+ +G  WAT++ + WL  +      EWEL+  KA +W+
Sbjct: 712  MAAQPAELVDSSG--WATILAVIWLHSNGKDLKCEWELLERKAVAWM 756


>gi|38195080 BCSC-1 isoform 1 [Homo sapiens]
          Length = 786

 Score =  225 bits (574), Expect = 2e-58
 Identities = 168/570 (29%), Positives = 269/570 (47%), Gaps = 95/570 (16%)

Query: 13  LPLTASDVTSCVSGYALGLTASLTYGNLEAQPFQGLFVYPLDECTTVIGFEAVIADRVVT 72
           +PL +  V+  +  +  G++A+L Y N E  P +  FV+P+DE + V  FEA++  + + 
Sbjct: 15  VPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIV 74

Query: 73  VQIKDKAKLESGHFDASHVRSPTVTGNILQDGVSIAPHSCTPGKVTLDEDLERILFVANL 132
            +++DK K  + +  A            L +G S +                R +F  N+
Sbjct: 75  AELQDKMKARTNYEKAISQGHQA----FLLEGDSSS----------------RDVFSCNV 114

Query: 133 GTIAPMENVTIFISTSSELPTLPSGAVRVLLPAVCAPTVPQFCTKSTGTSNQQAQGKDRH 192
           G + P     + +    ELP    GA+R +LPAV  P   QF    +G+S          
Sbjct: 115 GNLQPGSKAAVTLKYVQELPLEADGALRFVLPAVLNPRY-QF----SGSSKDSCLNVKTP 169

Query: 193 CFGAWAPGSWNKLCLATLLNTEVSNPMEYEFNFQLEIRGPCLLAGVESPTHEIRADAAPS 252
                 P       L+ +   +  + +E       +++  C L    SPT  +  D    
Sbjct: 170 I----VPVEDLPYTLSMVATIDSQHGIE-------KVQSNCPL----SPTEYLGEDKT-- 212

Query: 253 ARSAKSIIITLANKHTFDRPVEILIHPSEPHMPHVLIEKG--DMTLGEFDQHLKGRTDFI 310
                S  ++LA  H FDR VE+LI+ +E H P V++E G  +M  G    HL G     
Sbjct: 213 -----SAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPNMKPG----HLMGDPS-- 261

Query: 311 KGMKKKSRAERKTEIIRKRLHKDIPHHSVIMLNFCPDLQSVQPCLRKAHGEFIFLIDRSS 370
                                         M++F P++   QP      GEFIFL+DRS 
Sbjct: 262 -----------------------------AMVSFYPNIPEDQPS--NTCGEFIFLMDRSG 290

Query: 371 SM---------SGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDSL 421
           SM         S + +   K+ +++ LKSL   C FNI GFGS++++ FP S  Y++ ++
Sbjct: 291 SMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTM 350

Query: 422 AMACDDIQRMKADMGGTNILSPLKWVIRQPVHRGHPRLLFVITDGAVNNTGKVLELVRNH 481
             A   ++ M+AD+GGT IL+PL+ + R P   GHP  LFV TDG V +T  V++ VR +
Sbjct: 351 EEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRIN 410

Query: 482 AFSTRCYSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKSLKKAMAPVLSDVT 541
               RC+SFGIG      L+KG+A  S G++E +   +R+Q K +++LK+++ PV+ DV+
Sbjct: 411 RQKHRCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVS 470

Query: 542 VEWIFPETTEVLVSPVSASSLFPGERLVGY 571
           + W  P      +     + +F G+RL+ Y
Sbjct: 471 LSWHLPPGLSAKMLSPEQTVIFRGQRLISY 500



 Score = 37.4 bits (85), Expect = 0.088
 Identities = 15/47 (31%), Positives = 27/47 (57%), Gaps = 2/47 (4%)

Query: 1125 LGLEPRAVVEHTGKLWATVVGLAWLEHSSASYFTEWELVAAKANSWL 1171
            +  +P  +V+ +G  WAT++ + WL  +      EWEL+  KA +W+
Sbjct: 712  MAAQPAELVDSSG--WATILAVIWLHSNGKDLKCEWELLERKAVAWM 756


>gi|38195082 BCSC-1 isoform 2 [Homo sapiens]
          Length = 415

 Score =  164 bits (415), Expect = 5e-40
 Identities = 138/478 (28%), Positives = 216/478 (45%), Gaps = 95/478 (19%)

Query: 13  LPLTASDVTSCVSGYALGLTASLTYGNLEAQPFQGLFVYPLDECTTVIGFEAVIADRVVT 72
           +PL +  V+  +  +  G++A+L Y N E  P +  FV+P+DE + V  FEA++  + + 
Sbjct: 15  VPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIV 74

Query: 73  VQIKDKAKLESGHFDASHVRSPTVTGNILQDGVSIAPHSCTPGKVTLDEDLERILFVANL 132
            +++DK K  + +  A            L +G S +                R +F  N+
Sbjct: 75  AELQDKMKARTNYEKAISQGHQA----FLLEGDSSS----------------RDVFSCNV 114

Query: 133 GTIAPMENVTIFISTSSELPTLPSGAVRVLLPAVCAPTVPQFCTKSTGTSNQQAQGKDRH 192
           G + P     + +    ELP    GA+R +LPAV  P   QF    +G+S          
Sbjct: 115 GNLQPGSKAAVTLKYVQELPLEADGALRFVLPAVLNPRY-QF----SGSSKDSCLNVKTP 169

Query: 193 CFGAWAPGSWNKLCLATLLNTEVSNPMEYEFNFQLEIRGPCLLAGVESPTHEIRADAAPS 252
                 P       L+ +   +  + +E       +++  C L    SPT  +  D    
Sbjct: 170 I----VPVEDLPYTLSMVATIDSQHGIE-------KVQSNCPL----SPTEYLGEDKT-- 212

Query: 253 ARSAKSIIITLANKHTFDRPVEILIHPSEPHMPHVLIEKG--DMTLGEFDQHLKGRTDFI 310
                S  ++LA  H FDR VE+LI+ +E H P V++E G  +M  G    HL G     
Sbjct: 213 -----SAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPNMKPG----HLMGDPS-- 261

Query: 311 KGMKKKSRAERKTEIIRKRLHKDIPHHSVIMLNFCPDLQSVQPCLRKAHGEFIFLIDRSS 370
                                         M++F P++   QP      GEFIFL+DRS 
Sbjct: 262 -----------------------------AMVSFYPNIPEDQPS--NTCGEFIFLMDRSG 290

Query: 371 SM---------SGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDSL 421
           SM         S + +   K+ +++ LKSL   C FNI GFGS++++ FP S  Y++ ++
Sbjct: 291 SMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTM 350

Query: 422 AMACDDIQRMKADMGGTNILSPLKWVIRQPVHRGHPRLLFVITDGAVNNTGKVLELVR 479
             A   ++ M+AD+GGT IL+PL+ + R P   GHP  LFV TDG V +T  V++ VR
Sbjct: 351 EEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVR 408


>gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo
            sapiens]
          Length = 1724

 Score =  105 bits (263), Expect = 2e-22
 Identities = 121/543 (22%), Positives = 216/543 (39%), Gaps = 100/543 (18%)

Query: 36   TYGNLEAQPFQGLFVYPLDECTTVIGFEAVIADRVVTVQIKDKAKLESGHFDASHVRSPT 95
            TY N    P +  +++PLD+   V GFEA I  + +  +IK+K + +  + +A       
Sbjct: 644  TYTNKSHVPIEAKYIFPLDDKAAVCGFEAFINGKHIVGEIKEKEEAQQEYLEA------V 697

Query: 96   VTGNILQDGVSIAPHSCTPGKVTLDEDLERILFVANLGTIAPMENVTIFISTSSELPTLP 155
              G+               G   + +D   + F  ++G + P   V I I+  +EL  L 
Sbjct: 698  TQGH---------------GAYLMSQDAPDV-FTVSVGNLPPKAKVLIKITYITELSILG 741

Query: 156  SGAVRVLLPAVCAPTVPQFCTKSTGTSNQQAQGKDRHCFGAWAPGSWNKLCLATLLNTEV 215
            +  V   +PA  AP       +     N+  Q             +  K+C+  +   + 
Sbjct: 742  TVGV-FFMPATVAPW------QQDKALNENLQD------------TVEKICIKEIGTKQ- 781

Query: 216  SNPMEYEFNFQLEIRGPCLLAGVESPTHEIRADAAPSARSAKSIIITLANKHTFDRPVEI 275
                   F+  + I  P ++  + S THE++          K++I T+           +
Sbjct: 782  ------SFSLTMSIEMPYVIEFIFSDTHELKQKRT----DCKAVISTMEGSSLDSSGFSL 831

Query: 276  LIHPSEPHMPHVLIEKGDMTLGEFDQHLKGRTDFIKGMKKKSRAERKTEIIRKRLHKDIP 335
             I  S  ++P + +EK                            E+++E           
Sbjct: 832  HIGLSAAYLPRMWVEK--------------------------HPEKESE----------- 854

Query: 336  HHSVIMLNFCPDLQSVQPCLRKAHGEFIFLIDRSSSMSGISMHRVKDAMLVALKSLMPAC 395
                 ML F PDL    P L  +  E I  +D SSSM G++  + K   L AL  +    
Sbjct: 855  ---ACMLVFQPDLDVDLPDLA-SESEVIICLDCSSSMEGVTFLQAKQIALHALSLVGEKQ 910

Query: 396  LFNIIGFGSTFKSLFPSSQTYSEDSLAMACDDIQRMKADMGGTNILSPLKWVIRQPVHRG 455
              NII FG+ +K LF   +  + ++  MA + I      MG T+    L+++      RG
Sbjct: 911  KVNIIQFGTGYKELFSYPKHITSNT--MAAEFIMSATPTMGNTDFWKTLRYLSLLYPARG 968

Query: 456  HPRLLFVITDGAVNNTGKVLELVRNHAFSTRCYSFGIGPNVCHRLVKGLASVSEGSAELL 515
              R + +++DG + +    L+LV+     TR ++ GIG      +++ L+    G  E  
Sbjct: 969  -SRNILLVSDGHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHVLRILSQCGAGVFEYF 1027

Query: 516  MEGER--LQPKMVKSLKKAMAPVLSDVTVEW--IFPETTEVLVSPVSASSLFPGERLVGY 571
                +   + ++   + +  +P    V+V+W  + P+  E L +P    SLF  +RL+ Y
Sbjct: 1028 NAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAPAQVPSLFLNDRLLVY 1087

Query: 572  GIV 574
            G +
Sbjct: 1088 GFI 1090



 Score = 35.0 bits (79), Expect = 0.43
 Identities = 28/111 (25%), Positives = 48/111 (43%), Gaps = 9/111 (8%)

Query: 852  HHLAARAIIRDFEQLAEREGEIEQGSNRRYQVS-ALHTSKACNIISKYTAFVPVDVSKSR 910
            H LAARA+IRD+E     E E      ++   S  +  SK  ++I+++T+FV V+     
Sbjct: 1125 HKLAARALIRDYEDGILHENETSHEMKKQTLKSLIIKLSKENSLITQFTSFVAVEKRDEN 1184

Query: 911  YLPTVVEYPNSGAALRMLGSRAL----AQQWRGTSSGFGRPQTMLGEDSAP 957
              P    +P+      ++    +       W+G      R Q++L     P
Sbjct: 1185 ESP----FPDIPKVSELIAKEDVDFLPYMSWQGEPQEAVRNQSLLASSEWP 1231


>gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor 5
           isoform 3 [Homo sapiens]
          Length = 702

 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 64/244 (26%), Positives = 111/244 (45%), Gaps = 19/244 (7%)

Query: 363 IFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDSLA 422
           +F++D S+SM G  + + KDA+   L  L P   F+IIGF +  K       + + DS+ 
Sbjct: 297 VFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTPDSIR 356

Query: 423 MACDDIQRMKADMGGTNILSPLKWVIR----QPVHRG----HPRLLFVITDG----AVNN 470
                I  M +  GGT+I   L+  IR       H G       L+  +TDG       +
Sbjct: 357 DGKVYIHHM-SPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVGETH 415

Query: 471 TGKVLELVRNHAFSTRC-YSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKSL 529
           T K+L   R  A    C ++ GIG +V  RL++ L+  + G    + E E    +++   
Sbjct: 416 TLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDAGSQLIGFY 475

Query: 530 KKAMAPVLSDVTVEWIFPETTEVLVSPVSASSLFPGERLVGYGIVCDAS---LHISNPRS 586
            +   P+LSD+ ++  +P ++ V  +     + F G  ++  G + D     LH+    S
Sbjct: 476 DEIRTPLLSDIRID--YPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLHVEVTAS 533

Query: 587 DKRR 590
           + ++
Sbjct: 534 NSKK 537


>gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor 5
           isoform 1 [Homo sapiens]
          Length = 956

 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 64/244 (26%), Positives = 111/244 (45%), Gaps = 19/244 (7%)

Query: 363 IFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDSLA 422
           +F++D S+SM G  + + KDA+   L  L P   F+IIGF +  K       + + DS+ 
Sbjct: 297 VFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTPDSIR 356

Query: 423 MACDDIQRMKADMGGTNILSPLKWVIR----QPVHRG----HPRLLFVITDG----AVNN 470
                I  M +  GGT+I   L+  IR       H G       L+  +TDG       +
Sbjct: 357 DGKVYIHHM-SPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVGETH 415

Query: 471 TGKVLELVRNHAFSTRC-YSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKSL 529
           T K+L   R  A    C ++ GIG +V  RL++ L+  + G    + E E    +++   
Sbjct: 416 TLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDAGSQLIGFY 475

Query: 530 KKAMAPVLSDVTVEWIFPETTEVLVSPVSASSLFPGERLVGYGIVCDAS---LHISNPRS 586
            +   P+LSD+ ++  +P ++ V  +     + F G  ++  G + D     LH+    S
Sbjct: 476 DEIRTPLLSDIRID--YPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLHVEVTAS 533

Query: 587 DKRR 590
           + ++
Sbjct: 534 NSKK 537


>gi|153945711 inter-alpha trypsin inhibitor heavy chain precursor 5
           isoform 2 [Homo sapiens]
          Length = 742

 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 64/244 (26%), Positives = 111/244 (45%), Gaps = 19/244 (7%)

Query: 363 IFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDSLA 422
           +F++D S+SM G  + + KDA+   L  L P   F+IIGF +  K       + + DS+ 
Sbjct: 83  VFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTPDSIR 142

Query: 423 MACDDIQRMKADMGGTNILSPLKWVIR----QPVHRG----HPRLLFVITDG----AVNN 470
                I  M +  GGT+I   L+  IR       H G       L+  +TDG       +
Sbjct: 143 DGKVYIHHM-SPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVGETH 201

Query: 471 TGKVLELVRNHAFSTRC-YSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKSL 529
           T K+L   R  A    C ++ GIG +V  RL++ L+  + G    + E E    +++   
Sbjct: 202 TLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDAGSQLIGFY 261

Query: 530 KKAMAPVLSDVTVEWIFPETTEVLVSPVSASSLFPGERLVGYGIVCDAS---LHISNPRS 586
            +   P+LSD+ ++  +P ++ V  +     + F G  ++  G + D     LH+    S
Sbjct: 262 DEIRTPLLSDIRID--YPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLHVEVTAS 319

Query: 587 DKRR 590
           + ++
Sbjct: 320 NSKK 323


>gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens]
          Length = 911

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 56/229 (24%), Positives = 105/229 (45%), Gaps = 20/229 (8%)

Query: 363 IFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDSLA 422
           +F+ID S SM G  + + K+A+L  L  + P   F+++ FG+  +S   S    SE +L 
Sbjct: 294 VFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQ 353

Query: 423 MACDDIQRMKAD---------MGGTNILSPLKWVIRQPVHRGHPRLLFVITDG----AVN 469
            A D ++    D         + G  IL+ ++  +  P    H  +L ++TDG     V 
Sbjct: 354 AAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESL--PELSNHASILIMLTDGDPTEGVT 411

Query: 470 NTGKVLELVRNHAFSTR--CYSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVK 527
           +  ++L+ VRN A   R   Y+ G G NV    ++ ++  + G A+ + E      ++  
Sbjct: 412 DRSQILKNVRN-AIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQG 470

Query: 528 SLKKAMAPVLSDVTVEWIFPETTEVLVSPVSASSLFPGERLVGYGIVCD 576
              +   P+L DV ++  +P+   + ++       + G  +V  G + D
Sbjct: 471 FYSQVAKPLLVDVDLQ--YPQDAVLALTQNHHKQYYEGSEIVVAGRIAD 517


>gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens]
          Length = 930

 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 58/228 (25%), Positives = 102/228 (44%), Gaps = 18/228 (7%)

Query: 363 IFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDSLA 422
           +F+ID+S SMSG  + + ++A++  L  L P   FN+I F +      PS    S +++ 
Sbjct: 276 VFVIDKSGSMSGRKIQQTREALIKILDDLSPRDQFNLIVFSTEATQWRPSLVPASAENVN 335

Query: 423 MACDDIQRMKADMGGTNILSPLKWVIR--------QPVHRGHPRLLFVITDG----AVNN 470
            A      ++A +GGTNI   +   ++        + +  G   L+ ++TDG       N
Sbjct: 336 KARSFAAGIQA-LGGTNINDAMLMAVQLLDSSNQEERLPEGSVSLIILLTDGDPTVGETN 394

Query: 471 TGKVLELVRNHAFSTR--CYSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKS 528
              +   VR  A S R   +  G G +V +  ++ LA  + G A  + E      ++   
Sbjct: 395 PRSIQNNVR-EAVSGRYSLFCLGFGFDVSYAFLEKLALDNGGLARRIHEDSDSALQLQDF 453

Query: 529 LKKAMAPVLSDVTVEWIFPETTEVLVSPVSASSLFPGERLVGYGIVCD 576
            ++   P+L+ VT E  +P      V+  +   LF G  +V  G + D
Sbjct: 454 YQEVANPLLTAVTFE--YPSNAVEEVTQNNFRLLFKGSEMVVAGKLQD 499


>gi|70778918 inter-alpha globulin inhibitor H2 polypeptide [Homo
           sapiens]
          Length = 946

 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 50/223 (22%), Positives = 104/223 (46%), Gaps = 16/223 (7%)

Query: 363 IFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDSLA 422
           +F+ID S SM G+ M +  +AM   L  L     F++I F    ++      + ++  +A
Sbjct: 312 LFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIRTWRNDLISATKTQVA 371

Query: 423 MACDDIQRMKADMGGTNILSPLK---WVIRQPVHRG-----HPRLLFVITDGAVN----N 470
            A   I++++   GGTNI   L    +++ +  + G        L+ +++DG        
Sbjct: 372 DAKRYIEKIQPS-GGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSDGDPTVGELK 430

Query: 471 TGKVLELVR-NHAFSTRCYSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKSL 529
             K+ + V+ N   +   +S G+G +V +  +K L++ + G A+ +   +    ++ K  
Sbjct: 431 LSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQRIYGNQDTSSQLKKFY 490

Query: 530 KKAMAPVLSDVTVEWIFPETTEVLVSPVSASSLFPGERLVGYG 572
            +   P+L +  V++ +P T+   V+  +  + F G  +V  G
Sbjct: 491 NQVSTPLLRN--VQFNYPHTSVTDVTQNNFHNYFGGSEIVVAG 531


>gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein
           [Homo sapiens]
          Length = 890

 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 54/230 (23%), Positives = 100/230 (43%), Gaps = 16/230 (6%)

Query: 364 FLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDSLAM 423
           F+ID S SM+G  + + K+A+L  L+ +      N I F     +        + ++L  
Sbjct: 287 FVIDISGSMAGRKLEQTKEALLRILEDMQEEDYLNFILFSGDVSTWKEHLVQATPENLQE 346

Query: 424 ACDDIQRMKADMGGTNILSPLKWVI-----RQPVHRGHPR---LLFVITDGAVN----NT 471
           A   ++ M+ D G TNI   L   I      +  HR   R   ++ ++TDG  N      
Sbjct: 347 ARTFVKSME-DKGMTNINDGLLRGISMLNKAREEHRIPERSTSIVIMLTDGDANVGESRP 405

Query: 472 GKVLELVRNH-AFSTRCYSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKSLK 530
            K+ E VRN        Y+ G G N+ +  ++ +A  + G A  + E      ++    +
Sbjct: 406 EKIQENVRNAIGGKFPLYNLGFGNNLNYNFLENMALENHGFARRIYEDSDADLQLQGFYE 465

Query: 531 KAMAPVLSDVTVEWIFPETTEVLVSPVSASSLFPGERLVGYGIVCDASLH 580
           +   P+L+ V +E  +PE   + ++  +    + G  +V  G + D  ++
Sbjct: 466 EVANPLLTGVEME--YPENAILDLTQNTYQHFYDGSEIVVAGRLVDEDMN 513


>gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens]
          Length = 1313

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 73/306 (23%), Positives = 120/306 (39%), Gaps = 25/306 (8%)

Query: 363 IFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSE-DSL 421
           +F+ID SSSM G  M + K AM V L  L     FNII F  T           +   ++
Sbjct: 285 VFVIDVSSSMFGTKMEQTKTAMNVILSDLQANDYFNIISFSDTVNVWKAGGSIQATIQNV 344

Query: 422 AMACDDIQRMKADMGGTNILSPLKWVIRQPVHR----------GHPRLLFVITDG----A 467
             A D +  M+AD G T++ S L        H           G   L+  +TDG     
Sbjct: 345 HSAKDYLHCMEAD-GWTDVNSALLAAASVLNHSNQEPGRGPSVGRIPLIIFLTDGEPTAG 403

Query: 468 VNNTGKVLELVRNH-AFSTRCYSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMV 526
           V     +L  VR         +S   G +    L++ L+  + G A  + E      ++ 
Sbjct: 404 VTTPSVILSNVRQALGHRVSLFSLAFGDDADFTLLRRLSLENRGIARRIYEDTDAALQLK 463

Query: 527 KSLKKAMAPVLSDVTVEWIFPETTEVLVSPVSA-SSLFPGERLVGYGIVCDASLHISNPR 585
              ++   P+L+DV + ++      V  SP +   + F G  LV  G V      +    
Sbjct: 464 GLYEEISMPLLADVRLNYL---GGLVGASPWAVFPNYFGGSELVVAGQVQPGKQELGIHL 520

Query: 586 SDKRRRYSMLHSQESGSSVFYHSQDDG-PGLEGGDCA---KNSGAPFILGQAKNARLASG 641
           + +  +  +L +  S  +     +  G PG    + A   +   A   +G+  +A   + 
Sbjct: 521 AARGPKDQLLVAHHSEGATNNSQKAFGCPGEPAPNVAHFIRRLWAYVTIGELLDAHFQAR 580

Query: 642 DSTTKH 647
           D+TT+H
Sbjct: 581 DTTTRH 586


>gi|26051231 lactamase, beta isoform a [Homo sapiens]
          Length = 547

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 3/79 (3%)

Query: 772 PSHHPSAFETETSSDWDPPAESQERASPSRPATPAPVLGKALVKGLHDSQRLQWEVSFEL 831
           P+  P+A + E S   +PP E  +  +P  P TPAP   +   + +  S+ L   +  E+
Sbjct: 65  PAQSPAAPDPEASPLAEPPQE--QSLAPWSPQTPAPPCSRCFARAIESSRDLLHRIKDEV 122

Query: 832 GTPGPERGGAQDA-DLWSE 849
           G PG   G + D  ++WSE
Sbjct: 123 GAPGIVVGVSVDGKEVWSE 141


>gi|26051233 lactamase, beta isoform b [Homo sapiens]
          Length = 373

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 3/79 (3%)

Query: 772 PSHHPSAFETETSSDWDPPAESQERASPSRPATPAPVLGKALVKGLHDSQRLQWEVSFEL 831
           P+  P+A + E S   +PP E  +  +P  P TPAP   +   + +  S+ L   +  E+
Sbjct: 65  PAQSPAAPDPEASPLAEPPQE--QSLAPWSPQTPAPPCSRCFARAIESSRDLLHRIKDEV 122

Query: 832 GTPGPERGGAQDA-DLWSE 849
           G PG   G + D  ++WSE
Sbjct: 123 GAPGIVVGVSVDGKEVWSE 141


>gi|5031855 lymphocyte cytosolic protein 2 [Homo sapiens]
          Length = 533

 Score = 39.7 bits (91), Expect = 0.018
 Identities = 34/137 (24%), Positives = 58/137 (42%), Gaps = 14/137 (10%)

Query: 681 AAKRYPLRKARLQDLTNQTSLDVQRWQIDLQPLLNS-GQDLNQGPKLRGPGARRPSLLPQ 739
           A K+Y +  AR  +LT     D+Q++     P+L+   Q++N+  + R    R+P + P+
Sbjct: 35  AVKKYHIDGARFLNLTEN---DIQKFPKLRVPILSKLSQEINKNEERRSIFTRKPQV-PR 90

Query: 740 GCQPFLPWGQETQAWSPVRERT-------SDSRSPGDLEPSHHPSAFETETSSDWDPPAE 792
             +      ++   WS   E          D    GD E  +       E  +D++PP  
Sbjct: 91  FPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPS 150

Query: 793 SQERASPSR--PATPAP 807
           + E A  +   PA P P
Sbjct: 151 NDEEALQNSILPAKPFP 167


>gi|197333868 T-box 2 [Homo sapiens]
          Length = 712

 Score = 37.7 bits (86), Expect = 0.067
 Identities = 62/240 (25%), Positives = 93/240 (38%), Gaps = 20/240 (8%)

Query: 650 NLSQRRRAYSTNQITNHKPLPRATMASD----PMPAAKRYPLRKARLQDLTNQTSLDVQR 705
           N+S +      N +  ++P      A+D    P    + Y   +     +T   +  + +
Sbjct: 214 NISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQ 273

Query: 706 WQIDLQPLLNSGQDLNQGPKLRGPGARRPSL--LPQGCQPFLPWGQETQAWS----PVRE 759
            +ID  P     +D   G + +      PSL    + C+P    G E+ A S    P RE
Sbjct: 274 LKIDNNPFAKGFRDTGNGRREKRKQLTLPSLRLYEEHCKPERD-GAESDASSCDPPPARE 332

Query: 760 R-TSDSRSPGDLEPSHHPSAFETETSSDWDPPAE--SQERASPSRPATPAPVLGKALVKG 816
             TS   +P  L   H   A E   ++D DP  E  S+ERA      +PAP    A    
Sbjct: 333 PPTSPGAAPSPLR-LHRARAEEKSCAADSDPEPERLSEERAGAPLGRSPAP--DSASPTR 389

Query: 817 LHDSQRLQWEVSFELGTPGPERGGAQDADLWSETFHHLAARAIIRDFEQLAEREGEIEQG 876
           L + +R +   S E G    E GG  D      +     A A  +D  +    EG+ EQG
Sbjct: 390 LTEPERARERRSPERGKEPAESGG--DGPFGLRSLEKERAEARRKDEGRKEAAEGK-EQG 446


>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
          Length = 2803

 Score = 37.0 bits (84), Expect = 0.11
 Identities = 32/100 (32%), Positives = 44/100 (44%), Gaps = 6/100 (6%)

Query: 707  QIDLQPLLNSGQDLNQGPKLRGPGARRPSLLPQGCQPFLPWGQETQAWSPVRERTSDSRS 766
            ++   P L+S   L Q P    PGA   S LP+   P L  G  ++A +PV    ++  S
Sbjct: 2219 EVTKAPSLDSS--LPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFS 2276

Query: 767  PGDLEPSHHPSAFETETSSDWDPPAESQERASPSRPATPA 806
            P  LE +   S    E     +P A S    +P  PA PA
Sbjct: 2277 P-SLEAAEQESG---ELDPGMEPAAHSLWDLTPLSPAPPA 2312


>gi|126362971 serine/threonine kinase 10 [Homo sapiens]
          Length = 968

 Score = 36.2 bits (82), Expect = 0.20
 Identities = 35/140 (25%), Positives = 59/140 (42%), Gaps = 7/140 (5%)

Query: 752 QAWSPVRERTSDSRSPGDLEPSHHPSAF---ETETSSDWDPPAESQERASPSRPATP-AP 807
           +A + V E   D R  G+ E +   ++     T+ SS+  PP+ + ++     P+TP AP
Sbjct: 309 EAKAEVMEEIEDGRDEGEEEDAVDAASTLENHTQNSSEVSPPSLNADKPLEESPSTPLAP 368

Query: 808 VLGKALVK---GLHDSQRLQWEVSFELGTPGPERGGAQDADLWSETFHHLAARAIIRDFE 864
              +  V          R     S  +  PG E G A    L       + AR  +   +
Sbjct: 369 SQSQDSVNEPCSQPSGDRSLQTTSPPVVAPGNENGLAVPVPLRKSRPVSMDARIQVAQEK 428

Query: 865 QLAEREGEIEQGSNRRYQVS 884
           Q+AE+ G++   +NR  + S
Sbjct: 429 QVAEQGGDLSPAANRSQKAS 448


>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
          Length = 2263

 Score = 35.8 bits (81), Expect = 0.25
 Identities = 33/144 (22%), Positives = 67/144 (46%), Gaps = 16/144 (11%)

Query: 361  EFIFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIG---FGSTFKSLFPSSQTYS 417
            + +FL+D S+S+      ++K+ +   ++    +     IG   F  T+   FP      
Sbjct: 1000 DLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIG 1059

Query: 418  EDSLAMACDDIQRMKADMGGTNILSPLKWV-------IRQPVHRGHPRLLFVITDG-AVN 469
            E  ++   ++I+++    G T+I + L+ V       +   ++ G P++L V+TDG + +
Sbjct: 1060 EKEISFQIENIKQI---FGNTHIGAALREVEHYFRPDMGSRINTGTPQVLLVLTDGQSQD 1116

Query: 470  NTGKVLELVRNHAFSTRCYSFGIG 493
               +  E +R+       YS GIG
Sbjct: 1117 EVAQAAEALRHRGID--IYSVGIG 1138


>gi|31581524 cordon-bleu homolog [Homo sapiens]
          Length = 1261

 Score = 35.0 bits (79), Expect = 0.43
 Identities = 35/114 (30%), Positives = 45/114 (39%), Gaps = 26/114 (22%)

Query: 731  ARRPSLLPQGCQPFLPWGQETQAWSPVRERTSDS-RSPGDLEPSH--------------- 774
            A  P   P G  P  P   +TQA S  RE  + S R+PG  EPSH               
Sbjct: 1009 ASEPRRAPDGTDPPPPHTSDTQACS--RELVNGSVRAPGHGEPSHPPGGSGTESHILLER 1066

Query: 775  --HPSAFET---ETSSDWDPP---AESQERASPSRPATPAPVLGKALVKGLHDS 820
               PS F T   ET S W P     + + +    RP      L  AL++ +H +
Sbjct: 1067 EEKPSVFSTDGNETDSIWPPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSA 1120


>gi|150417978 platelet glycoprotein Ib alpha polypeptide precursor
            [Homo sapiens]
          Length = 639

 Score = 34.7 bits (78), Expect = 0.57
 Identities = 23/71 (32%), Positives = 32/71 (45%), Gaps = 5/71 (7%)

Query: 1051 QLASGAFLLNEAFCEATHIPMEKLKWTSPFTCHRVSLT--TRPSESKTPSPQLCTSSPPR 1108
            Q+ S      E+  E T  P    +WT  FT H  S+T    P  +  P+P   TS P  
Sbjct: 337  QMPSSLHPTQESTKEQTTFPP---RWTPNFTLHMESITFSKTPKSTTEPTPSPTTSEPVP 393

Query: 1109 HPSCDSFSLEP 1119
             P+ +  +LEP
Sbjct: 394  EPAPNMTTLEP 404


>gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]
          Length = 1505

 Score = 34.3 bits (77), Expect = 0.74
 Identities = 35/111 (31%), Positives = 43/111 (38%), Gaps = 6/111 (5%)

Query: 705  RWQIDLQPLLNSG----QDLNQGPKLRGPGARRPSLLPQGCQPFLPWGQETQAWSPVRER 760
            R Q+ L   L  G    Q   QGP L    + +  L  QGC       + + + SP  E 
Sbjct: 1001 RMQLWLNGELGQGVLPVQGQQQGPVLHSVTSLQDPL-QQGCVSSESTPKTSASCSPAPES 1059

Query: 761  T-SDSRSPGDLEPSHHPSAFETETSSDWDPPAESQERASPSRPATPAPVLG 810
              S S S   L           E S D  PP  S   AS S+P TP P+ G
Sbjct: 1060 PMSSSESVKSLTELVQQPCPPIEASKDSKPPEPSDPPASDSQPTTPLPLSG 1110


>gi|21237808 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c2 isoform b [Homo sapiens]
          Length = 1130

 Score = 34.3 bits (77), Expect = 0.74
 Identities = 27/82 (32%), Positives = 36/82 (43%), Gaps = 7/82 (8%)

Query: 723  GPKLRGP-GARRPSLLPQGCQPFLPWGQETQAWSPV-RERTSDSRSPGDLEPSHHPSAFE 780
            GP+ + P GA +P  +P G  P  P G      SP   ++T  S  PG +  S HP   +
Sbjct: 1052 GPQQQQPAGAPQPGAVPPGVPPPGPHGP-----SPFPNQQTPPSMMPGAVPGSGHPGVAD 1106

Query: 781  TETSSDWDPPAESQERASPSRP 802
              T    DP A S    +P  P
Sbjct: 1107 PGTPLPPDPTAPSPGTVTPVPP 1128


>gi|148762963 armadillo repeat containing 2 [Homo sapiens]
          Length = 867

 Score = 33.9 bits (76), Expect = 0.97
 Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 2/64 (3%)

Query: 742 QPFLPWGQETQAWSPVRERTSDSRSPGDLEPSHHPSAFETETSSDWDPPAESQERASPSR 801
           +PF P   + + + P   RTS++R P     S H S+FE+  S        S     P  
Sbjct: 44  RPFTPQEAQRKLFGPASSRTSENRPPSSF--SLHASSFESSDSRPISGTRLSPLELKPKV 101

Query: 802 PATP 805
           PA+P
Sbjct: 102 PASP 105


>gi|4502131 amyloid beta A4 precursor protein-binding, family B,
           member 1 isoform E9 [Homo sapiens]
          Length = 710

 Score = 33.5 bits (75), Expect = 1.3
 Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 36/122 (29%)

Query: 750 ETQAWSPVRERTSDSRSPGDLEPSHHPSAFETET-----------------------SSD 786
           E  +W+ + + +    SP D +   +P+AFET++                       ++ 
Sbjct: 220 EDSSWATLSQGSPSYGSPEDTDSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQ 279

Query: 787 WDPPAESQERASPSRPATPAPV-----LGKALVKGLHDSQRLQWEVS----FELGTPGPE 837
           W+PP     RASPS+ ++P         G A  +G  D +  + E S     ELG   PE
Sbjct: 280 WEPPG----RASPSQGSSPQEESQLTWTGFAHGEGFEDGEFWKDEPSDEAPMELGLKEPE 335

Query: 838 RG 839
            G
Sbjct: 336 EG 337


>gi|22035554 amyloid beta A4 precursor protein-binding, family B,
           member 1 isoform delta E9 [Homo sapiens]
          Length = 708

 Score = 33.5 bits (75), Expect = 1.3
 Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 36/122 (29%)

Query: 750 ETQAWSPVRERTSDSRSPGDLEPSHHPSAFETET-----------------------SSD 786
           E  +W+ + + +    SP D +   +P+AFET++                       ++ 
Sbjct: 220 EDSSWATLSQGSPSYGSPEDTDSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQ 279

Query: 787 WDPPAESQERASPSRPATPAPV-----LGKALVKGLHDSQRLQWEVS----FELGTPGPE 837
           W+PP     RASPS+ ++P         G A  +G  D +  + E S     ELG   PE
Sbjct: 280 WEPPG----RASPSQGSSPQEESQLTWTGFAHGEGFEDGEFWKDEPSDEAPMELGLKEPE 335

Query: 838 RG 839
            G
Sbjct: 336 EG 337


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 33.5 bits (75), Expect = 1.3
 Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 2/77 (2%)

Query: 590 RRYSMLHSQESGSSVFYHSQDDGPGLEGGDCAKNSGAPFILGQAKNARLASGDSTTKHDL 649
           +R     S ES S      +DD   L    C K  G+P +L         S  ST+ H  
Sbjct: 471 KRSDKFCSSESESESSESGEDDRDSLGSSGCLK--GSPLVLKDPSLFSSLSASSTSSHGS 528

Query: 650 NLSQRRRAYSTNQITNH 666
           + +Q++    T+Q T H
Sbjct: 529 SAAQKQNPSHTDQHTKH 545


>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
          Length = 1512

 Score = 33.5 bits (75), Expect = 1.3
 Identities = 54/224 (24%), Positives = 87/224 (38%), Gaps = 29/224 (12%)

Query: 587 DKRRRYSMLHSQESGSSVFYHSQDDGPGLEGGDCAKNSGAPFILGQAKNARLASGDSTTK 646
           + RRR       E+  S   HS     G E  + AK+  +    G+ K+A   S  S+++
Sbjct: 215 EHRRRDGQRGGSEASKSRSRHSHS---GEERAEVAKSGSSSSSGGRRKSASATSSSSSSR 271

Query: 647 HDLNL-SQRRRAYSTNQITN-HKPLPRATMASDPMPAAKRYPLRKARLQDLTNQTSLDVQ 704
            D +  + R R  S+ +  + +K  P+A       P A R   R+  L  L  +    V 
Sbjct: 272 KDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYR---RRRSLSPLGGRDDSPVS 328

Query: 705 RWQIDLQPLLNSGQDLN--QGPKLRGPGARRPSL-LPQGCQPFLPWGQETQAWSPVRERT 761
                      + Q L   + P   G G+   S  LP+   P+      ++  SP   R 
Sbjct: 329 H---------RASQSLRSRKSPSPAGGGSSPYSRRLPRSPSPY------SRRRSPSYSRH 373

Query: 762 SDSRSPGDLEPSHHPSAFETETSSDWDPPAESQERASPSRPATP 805
           S     GD+ PS + S+    + S + P      R+  SR  +P
Sbjct: 374 SSYERGGDVSPSPYSSSSWRRSRSPYSPVL---RRSGKSRSRSP 414


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,076,203
Number of Sequences: 37866
Number of extensions: 2359560
Number of successful extensions: 7933
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 75
Number of HSP's that attempted gapping in prelim test: 7788
Number of HSP's gapped (non-prelim): 212
length of query: 1215
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1101
effective length of database: 13,930,794
effective search space: 15337804194
effective search space used: 15337804194
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.