BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo sapiens] (677 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s... 1389 0.0 gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ... 1389 0.0 gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ... 1389 0.0 gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo s... 1389 0.0 gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo s... 268 1e-71 gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens] 262 7e-70 gi|66932916 mitogen-activated protein kinase 1 [Homo sapiens] 262 7e-70 gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo s... 246 5e-65 gi|20128774 mitogen-activated protein kinase 11 [Homo sapiens] 246 5e-65 gi|20986512 mitogen-activated protein kinase 14 isoform 2 [Homo ... 231 2e-60 gi|4503069 mitogen-activated protein kinase 14 isoform 1 [Homo s... 228 2e-59 gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens] 220 4e-57 gi|158138507 mitogen-activated protein kinase 3 isoform 3 [Homo ... 218 1e-56 gi|149408126 nemo like kinase [Homo sapiens] 206 4e-53 gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens] 201 2e-51 gi|48255970 mitogen-activated protein kinase 12 [Homo sapiens] 192 1e-48 gi|21237742 mitogen-activated protein kinase 9 isoform JNK2 beta... 188 2e-47 gi|21237745 mitogen-activated protein kinase 9 isoform JNK2 beta... 187 2e-47 gi|20986523 mitogen-activated protein kinase 8 isoform JNK1 alph... 182 7e-46 gi|4506095 mitogen-activated protein kinase 8 isoform JNK1 alpha... 182 7e-46 gi|20986514 mitogen-activated protein kinase 14 isoform 3 [Homo ... 182 7e-46 gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens] 181 2e-45 gi|21237739 mitogen-activated protein kinase 9 isoform JNK2 alph... 179 6e-45 gi|21237736 mitogen-activated protein kinase 9 isoform JNK2 alph... 179 7e-45 gi|20986521 mitogen-activated protein kinase 8 isoform JNK1 beta... 177 4e-44 gi|20986519 mitogen-activated protein kinase 8 isoform JNK1 beta... 177 4e-44 gi|4506081 mitogen-activated protein kinase 10 isoform 1 [Homo s... 176 5e-44 gi|20986510 mitogen-activated protein kinase 10 isoform 2 [Homo ... 176 5e-44 gi|20986508 mitogen-activated protein kinase 10 isoform 4 [Homo ... 176 5e-44 gi|20986506 mitogen-activated protein kinase 10 isoform 3 [Homo ... 176 5e-44 >gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo sapiens] Length = 816 Score = 1389 bits (3596), Expect = 0.0 Identities = 677/677 (100%), Positives = 677/677 (100%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG Sbjct: 140 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 199 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR Sbjct: 200 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 259 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ Sbjct: 260 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 319 Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE Sbjct: 320 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 379 Query: 241 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 300 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP Sbjct: 380 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 439 Query: 301 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 360 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL Sbjct: 440 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 499 Query: 361 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 420 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL Sbjct: 500 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 559 Query: 421 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 480 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ Sbjct: 560 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 619 Query: 481 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 540 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS Sbjct: 620 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 679 Query: 541 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 600 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA Sbjct: 680 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 739 Query: 601 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 660 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI Sbjct: 740 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 799 Query: 661 QMDSPMLLADLPDLQDP 677 QMDSPMLLADLPDLQDP Sbjct: 800 QMDSPMLLADLPDLQDP 816 >gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo sapiens] Length = 816 Score = 1389 bits (3596), Expect = 0.0 Identities = 677/677 (100%), Positives = 677/677 (100%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG Sbjct: 140 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 199 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR Sbjct: 200 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 259 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ Sbjct: 260 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 319 Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE Sbjct: 320 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 379 Query: 241 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 300 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP Sbjct: 380 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 439 Query: 301 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 360 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL Sbjct: 440 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 499 Query: 361 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 420 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL Sbjct: 500 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 559 Query: 421 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 480 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ Sbjct: 560 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 619 Query: 481 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 540 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS Sbjct: 620 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 679 Query: 541 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 600 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA Sbjct: 680 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 739 Query: 601 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 660 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI Sbjct: 740 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 799 Query: 661 QMDSPMLLADLPDLQDP 677 QMDSPMLLADLPDLQDP Sbjct: 800 QMDSPMLLADLPDLQDP 816 >gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo sapiens] Length = 816 Score = 1389 bits (3596), Expect = 0.0 Identities = 677/677 (100%), Positives = 677/677 (100%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG Sbjct: 140 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 199 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR Sbjct: 200 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 259 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ Sbjct: 260 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 319 Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE Sbjct: 320 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 379 Query: 241 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 300 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP Sbjct: 380 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 439 Query: 301 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 360 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL Sbjct: 440 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 499 Query: 361 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 420 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL Sbjct: 500 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 559 Query: 421 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 480 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ Sbjct: 560 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 619 Query: 481 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 540 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS Sbjct: 620 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 679 Query: 541 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 600 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA Sbjct: 680 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 739 Query: 601 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 660 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI Sbjct: 740 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 799 Query: 661 QMDSPMLLADLPDLQDP 677 QMDSPMLLADLPDLQDP Sbjct: 800 QMDSPMLLADLPDLQDP 816 >gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo sapiens] Length = 677 Score = 1389 bits (3596), Expect = 0.0 Identities = 677/677 (100%), Positives = 677/677 (100%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG Sbjct: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR Sbjct: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ Sbjct: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180 Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE Sbjct: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240 Query: 241 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 300 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP Sbjct: 241 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 300 Query: 301 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 360 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL Sbjct: 301 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 360 Query: 361 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 420 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL Sbjct: 361 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 420 Query: 421 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 480 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ Sbjct: 421 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 480 Query: 481 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 540 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS Sbjct: 481 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 540 Query: 541 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 600 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA Sbjct: 541 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 600 Query: 601 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 660 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI Sbjct: 601 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 660 Query: 661 QMDSPMLLADLPDLQDP 677 QMDSPMLLADLPDLQDP Sbjct: 661 QMDSPMLLADLPDLQDP 677 >gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo sapiens] Length = 379 Score = 268 bits (685), Expect = 1e-71 Identities = 130/249 (52%), Positives = 177/249 (71%), Gaps = 2/249 (0%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 ME+DL++++ S Q L+ +H+ YFLYQ+LRGLKY+HSA V+HRDLKPSNLL+N C+LKI Sbjct: 125 METDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKIC 183 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR + +H F+TEYVATRWYRAPE+ML+ YT++ID+WSVGCI EML+ R Sbjct: 184 DFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 242 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180 +FPGK+Y+ QL I+ +LG+PS + + + R Y+QSLP + V W ++P +D + Sbjct: 243 PIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSK 302 Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240 AL LL RML F P+ RI+ AL HP+L +Y+DP DEP PF FA + + L +ER+KE Sbjct: 303 ALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKE 362 Query: 241 AIVAEIEDF 249 I E F Sbjct: 363 LIFQETARF 371 >gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens] Length = 360 Score = 262 bits (670), Expect = 7e-70 Identities = 127/249 (51%), Positives = 174/249 (69%), Gaps = 2/249 (0%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 ME+DL++++ +Q L+ +H+ YFLYQ+LRGLKY+HSA V+HRDLKPSNLL+N C+LKI Sbjct: 108 METDLYKLL-KTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKIC 166 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR + +H F+TEYVATRWYRAPE+ML+ YT++ID+WSVGCI EML+ R Sbjct: 167 DFGLAR-VADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 225 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180 +FPGK+Y+ QL I+ +LG+PS + + + R Y+ SLP + VPW ++P AD + Sbjct: 226 PIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSK 285 Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240 AL LL +ML F P RI AL HP+L +Y+DP DEP PF F + + L +E++KE Sbjct: 286 ALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKE 345 Query: 241 AIVAEIEDF 249 I E F Sbjct: 346 LIFEETARF 354 >gi|66932916 mitogen-activated protein kinase 1 [Homo sapiens] Length = 360 Score = 262 bits (670), Expect = 7e-70 Identities = 127/249 (51%), Positives = 174/249 (69%), Gaps = 2/249 (0%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 ME+DL++++ +Q L+ +H+ YFLYQ+LRGLKY+HSA V+HRDLKPSNLL+N C+LKI Sbjct: 108 METDLYKLL-KTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKIC 166 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR + +H F+TEYVATRWYRAPE+ML+ YT++ID+WSVGCI EML+ R Sbjct: 167 DFGLAR-VADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 225 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180 +FPGK+Y+ QL I+ +LG+PS + + + R Y+ SLP + VPW ++P AD + Sbjct: 226 PIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSK 285 Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240 AL LL +ML F P RI AL HP+L +Y+DP DEP PF F + + L +E++KE Sbjct: 286 ALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKE 345 Query: 241 AIVAEIEDF 249 I E F Sbjct: 346 LIFEETARF 354 >gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo sapiens] Length = 357 Score = 246 bits (628), Expect = 5e-65 Identities = 118/222 (53%), Positives = 162/222 (72%), Gaps = 2/222 (0%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 ME+DL++++ S Q L+ +H+ YFLYQ+LRGLKY+HSA V+HRDLKPSNLL+N C+LKI Sbjct: 125 METDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKIC 183 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR + +H F+TEYVATRWYRAPE+ML+ YT++ID+WSVGCI EML+ R Sbjct: 184 DFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 242 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180 +FPGK+Y+ QL I+ +LG+PS + + + R Y+QSLP + V W ++P +D + Sbjct: 243 PIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSK 302 Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAP 222 AL LL RML F P+ RI+ AL HP+L +Y+DP DE +P Sbjct: 303 ALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEVGQSP 344 >gi|20128774 mitogen-activated protein kinase 11 [Homo sapiens] Length = 364 Score = 246 bits (628), Expect = 5e-65 Identities = 126/249 (50%), Positives = 171/249 (68%), Gaps = 9/249 (3%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M +DL+ I+ Q L+ EHV++ +YQLLRGLKY+HSA +IHRDLKPSN+ VNE+CEL+I Sbjct: 109 MGADLNNIV-KCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRIL 167 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR A+ + MT YVATRWYRAPE+ML+ Y Q +D+WSVGCI E+L + Sbjct: 168 DFGLAR-----QADEE--MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGK 220 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180 LFPG +Y+ QL+ IM V+GTPSP V+ + +E R YIQSLPP +++ GA+ Sbjct: 221 ALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPL 280 Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240 A+ LLGRML + R+SAA AL H + ++YHDP+DEP+ A P+D + + + T E KE Sbjct: 281 AIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPE-AEPYDESVEAKERTLEEWKE 339 Query: 241 AIVAEIEDF 249 E+ F Sbjct: 340 LTYQEVLSF 348 >gi|20986512 mitogen-activated protein kinase 14 isoform 2 [Homo sapiens] Length = 360 Score = 231 bits (588), Expect = 2e-60 Identities = 120/249 (48%), Positives = 164/249 (65%), Gaps = 9/249 (3%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M +DL+ I+ Q LT +HV++ +YQ+LRGLKY+HSA +IHRDLKPSNL VNE+CELKI Sbjct: 109 MGADLNNIV-KCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKIL 167 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR MT YVATRWYRAPE+ML+ Y Q +D+WSVGCI E+L R Sbjct: 168 DFGLARHTDDE-------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGR 220 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180 LFPG +++ QL+LI+ ++GTP +++ + +E R YIQSL + + V+ GA+ Sbjct: 221 TLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPL 280 Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240 A+ LL +ML + RI+AA AL H + A+YHDPDDEP A P+D +F+ L + K Sbjct: 281 AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEP-VADPYDQSFESRDLLIDEWKS 339 Query: 241 AIVAEIEDF 249 E+ F Sbjct: 340 LTYDEVISF 348 >gi|4503069 mitogen-activated protein kinase 14 isoform 1 [Homo sapiens] Length = 360 Score = 228 bits (580), Expect = 2e-59 Identities = 121/249 (48%), Positives = 161/249 (64%), Gaps = 9/249 (3%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M +DL+ I+ Q LT +HV++ +YQ+LRGLKY+HSA +IHRDLKPSNL VNE+CELKI Sbjct: 109 MGADLNNIV-KCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKIL 167 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR MT YVATRWYRAPE+ML+ Y Q +D+WSVGCI E+L R Sbjct: 168 DFGLARHTDDE-------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGR 220 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180 LFPG ++++QLQ IM + GTP +I + + R YIQSL + + V+ GA+ Sbjct: 221 TLFPGTDHINQLQQIMRLTGTPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPL 280 Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240 A+ LL +ML + RI+AA AL H + A+YHDPDDEP A P+D +F+ L + K Sbjct: 281 AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEP-VADPYDQSFESRDLLIDEWKS 339 Query: 241 AIVAEIEDF 249 E+ F Sbjct: 340 LTYDEVISF 348 >gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens] Length = 365 Score = 220 bits (560), Expect = 4e-57 Identities = 117/260 (45%), Positives = 164/260 (63%), Gaps = 11/260 (4%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M++DL +I+ + E ++Y +YQ+L+GLKY+HSA V+HRDLKP NL VNE+CELKI Sbjct: 110 MQTDLQKIM--GMEFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKIL 167 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR + AE MT YV TRWYRAPE++LS Y Q +D+WSVGCI EML + Sbjct: 168 DFGLARH---ADAE----MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGK 220 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180 LF GK+Y+ QL I+ V G P +Q + + ++YIQSLP + ++P A Q Sbjct: 221 TLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQSLPQTPRKDFTQLFPRASPQ 280 Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240 A LL +ML + R++AA AL HPF + DP++E + PFD + + E LT + K+ Sbjct: 281 AADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQQPFDDSLEHEKLTVDEWKQ 340 Query: 241 AIVAEIEDFH--ARREGIRQ 258 I EI +F AR++ R+ Sbjct: 341 HIYKEIVNFSPIARKDSRRR 360 >gi|158138507 mitogen-activated protein kinase 3 isoform 3 [Homo sapiens] Length = 335 Score = 218 bits (555), Expect = 1e-56 Identities = 116/249 (46%), Positives = 152/249 (61%), Gaps = 46/249 (18%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 ME+DL++++ S Q L+ +H+ YFLYQ+LRGLKY+HSA V+HRDLKPSNLL+N C+LKI Sbjct: 125 METDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKIC 183 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR + +H F+TEYVATRWYRAPE+ML+ YT++ID+WSVGCI EML+ R Sbjct: 184 DFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 242 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180 +FPGK+Y+ QL I+ Sbjct: 243 PIFPGKHYLDQLNHIL-------------------------------------------- 258 Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240 AL LL RML F P+ RI+ AL HP+L +Y+DP DEP PF FA + + L +ER+KE Sbjct: 259 ALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKE 318 Query: 241 AIVAEIEDF 249 I E F Sbjct: 319 LIFQETARF 327 >gi|149408126 nemo like kinase [Homo sapiens] Length = 527 Score = 206 bits (525), Expect = 4e-53 Identities = 120/264 (45%), Positives = 162/264 (61%), Gaps = 26/264 (9%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M+SDLH+II S QPL+ +HV+ FLYQ+LRGLKY+HSA ++HRD+KP NLLVN NC LKI Sbjct: 222 MQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKIC 281 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR + MT+ V T++YRAPE+++ Y+ AID+WSVGCIF E+L RR Sbjct: 282 DFGLAR---VEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRR 338 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQP-VP-WETVYPGAD 178 LF ++ + QL LI +LGTPS ++ E +A+I P +QP +P T+ A Sbjct: 339 ILFQAQSPIQQLDLITDLLGTPSLEAMR-TACEGAKAHILRGPHKQPSLPVLYTLSSQAT 397 Query: 179 RQALSLLGRMLRFEPSARISAAAALRHPFL----AKYH----------------DPDDEP 218 +A+ LL RML F+PS RISA AL HP+L +YH D EP Sbjct: 398 HEAVHLLCRMLVFDPSKRISAKDALAHPYLDEGRLRYHTCMCKCCFSTSTGRVYTSDFEP 457 Query: 219 DCAPPFDFAFDREALTRERIKEAI 242 P FD F++ + ++KE I Sbjct: 458 VTNPKFDDTFEKNLSSVRQVKEII 481 >gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens] Length = 544 Score = 201 bits (510), Expect = 2e-51 Identities = 130/354 (36%), Positives = 183/354 (51%), Gaps = 33/354 (9%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M++DL+ +I L HVR YQLLR +++HS V+HRD KPSN+L++ NC +K+ Sbjct: 95 MDTDLNAVIRKGGLLQDVHVRSIFYQLLRATRFLHSGHVVHRDQKPSNVLLDANCTVKLC 154 Query: 61 DFGMARGLCTSP-AEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR 119 DFG+AR L P +TEYVATRWYRAPE++LS H YT +D+WS+GCI GEML Sbjct: 155 DFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEVLLSSHRYTLGVDMWSLGCILGEMLRG 214 Query: 120 RQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSL--PPRQPVPWETVYPGA 177 R LFPG + +HQL+LI+ + PS + A+G+ + + L PRQ + + P Sbjct: 215 RPLFPGTSTLHQLELILETIPPPSEEDLLALGSGCRASVLHQLGSRPRQTLD-ALLPPDT 273 Query: 178 DRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRER 237 +AL LL R+L F P R+SA AL+HP++ ++H P DE + REA R R Sbjct: 274 SPEALDLLRRLLVFAPDKRLSATQALQHPYVQRFHCPSDE----------WAREADVRPR 323 Query: 238 IKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSP---WAPSGDCAMES 294 E + + ++ +R + Q I + E G P+ PS P D + S Sbjct: 324 AHEGVQLSVPEYRSR---VYQMILECGGSSGTSREKG-PEGVSPSQAHLHKPRADPQLPS 379 Query: 295 PPPAPPPCPGPAPDTIDLTLQPPP---PVSEPAPPKKDGAISDNTKAALKAALL 345 P P P P Q P P +P N+ L+ ALL Sbjct: 380 RTPVQGPRPRP---------QSSPGHDPAEHESPRAAKNVPRQNSAPLLQTALL 424 >gi|48255970 mitogen-activated protein kinase 12 [Homo sapiens] Length = 367 Score = 192 bits (487), Expect = 1e-48 Identities = 99/254 (38%), Positives = 153/254 (60%), Gaps = 9/254 (3%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M +DL +++ + L + +++ +YQ+L+GL+Y+H+A +IHRDLKP NL VNE+CELKI Sbjct: 112 MGTDLGKLM-KHEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKIL 170 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR + MT YV TRWYRAPE++L+ YTQ +D+WSVGCI EM+ + Sbjct: 171 DFGLARQADSE-------MTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGK 223 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180 LF G +++ QL+ IM V GTP +Q + ++ + Y++ LP + + ++ A Sbjct: 224 TLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASILTNASPL 283 Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240 A++LL +ML + R++A AL HP+ HD +DEP +D +FD T + K Sbjct: 284 AVNLLEKMLVLDAEQRVTAGEALAHPYFESLHDTEDEPQ-VQKYDDSFDDVDRTLDEWKR 342 Query: 241 AIVAEIEDFHARRE 254 E+ F R+ Sbjct: 343 VTYKEVLSFKPPRQ 356 >gi|21237742 mitogen-activated protein kinase 9 isoform JNK2 beta1 [Homo sapiens] Length = 382 Score = 188 bits (477), Expect = 2e-47 Identities = 110/282 (39%), Positives = 165/282 (58%), Gaps = 28/282 (9%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M+++L Q+IH L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI Sbjct: 111 MDANLCQVIHME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR CT+ + MT YV TR+YRAPE++L + Y + +D+WSVGCI EM+ + Sbjct: 169 DFGLARTACTN-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMAEMVLHK 222 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176 LFPG++Y+ Q ++ LGTPS ++ + VR Y+++ P + +E ++P Sbjct: 223 VLFPGRDYIDQWNKVIEQLGTPSAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFP 281 Query: 177 --------ADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226 QA LL +ML +P RIS ALRHP++ ++DP E + PP +D Sbjct: 282 SESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDP-AEAEAPPPQIYDA 340 Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPSLQ 267 + E KE I E+ D+ R + G+ ++ QPS Q Sbjct: 341 QLEEREHAIEEWKELIYKEVMDWEERSKNGV---VKDQPSAQ 379 >gi|21237745 mitogen-activated protein kinase 9 isoform JNK2 beta2 [Homo sapiens] Length = 424 Score = 187 bits (476), Expect = 2e-47 Identities = 111/286 (38%), Positives = 167/286 (58%), Gaps = 28/286 (9%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M+++L Q+IH L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI Sbjct: 111 MDANLCQVIHME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR CT+ + MT YV TR+YRAPE++L + Y + +D+WSVGCI EM+ + Sbjct: 169 DFGLARTACTN-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMAEMVLHK 222 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176 LFPG++Y+ Q ++ LGTPS ++ + VR Y+++ P + +E ++P Sbjct: 223 VLFPGRDYIDQWNKVIEQLGTPSAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFP 281 Query: 177 --------ADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226 QA LL +ML +P RIS ALRHP++ ++DP E + PP +D Sbjct: 282 SESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDP-AEAEAPPPQIYDA 340 Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPSLQPVAS 271 + E KE I E+ D+ R + G+ ++ QPS V+S Sbjct: 341 QLEEREHAIEEWKELIYKEVMDWEERSKNGV---VKDQPSDAAVSS 383 >gi|20986523 mitogen-activated protein kinase 8 isoform JNK1 alpha2 [Homo sapiens] Length = 427 Score = 182 bits (463), Expect = 7e-46 Identities = 115/280 (41%), Positives = 163/280 (58%), Gaps = 28/280 (10%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M+++L Q+I L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI Sbjct: 111 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR TS + MT YV TR+YRAPE++L + Y + +DLWSVGCI GEM+ + Sbjct: 169 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDLWSVGCIMGEMVCHK 222 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176 LFPG++Y+ Q ++ LGTP P ++ + VR Y+++ P +E ++P Sbjct: 223 ILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFP 281 Query: 177 AD--------RQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPF--DF 226 AD QA LL +ML + S RIS AL+HP++ ++DP E + PP D Sbjct: 282 ADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDP-SEAEAPPPKIPDK 340 Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265 D T E KE I E+ D R + G+ IR QPS Sbjct: 341 QLDEREHTIEEWKELIYKEVMDLEERTKNGV---IRGQPS 377 >gi|4506095 mitogen-activated protein kinase 8 isoform JNK1 alpha1 [Homo sapiens] Length = 384 Score = 182 bits (463), Expect = 7e-46 Identities = 115/280 (41%), Positives = 163/280 (58%), Gaps = 28/280 (10%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M+++L Q+I L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI Sbjct: 111 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR TS + MT YV TR+YRAPE++L + Y + +DLWSVGCI GEM+ + Sbjct: 169 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDLWSVGCIMGEMVCHK 222 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176 LFPG++Y+ Q ++ LGTP P ++ + VR Y+++ P +E ++P Sbjct: 223 ILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFP 281 Query: 177 AD--------RQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPF--DF 226 AD QA LL +ML + S RIS AL+HP++ ++DP E + PP D Sbjct: 282 ADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDP-SEAEAPPPKIPDK 340 Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265 D T E KE I E+ D R + G+ IR QPS Sbjct: 341 QLDEREHTIEEWKELIYKEVMDLEERTKNGV---IRGQPS 377 >gi|20986514 mitogen-activated protein kinase 14 isoform 3 [Homo sapiens] Length = 297 Score = 182 bits (463), Expect = 7e-46 Identities = 91/178 (51%), Positives = 124/178 (69%), Gaps = 8/178 (4%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M +DL+ I+ Q LT +HV++ +YQ+LRGLKY+HSA +IHRDLKPSNL VNE+CELKI Sbjct: 109 MGADLNNIV-KCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKIL 167 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR MT YVATRWYRAPE+ML+ Y Q +D+WSVGCI E+L R Sbjct: 168 DFGLARHTDDE-------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGR 220 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGAD 178 LFPG +++ QL+LI+ ++GTP +++ + +E R YIQSL + + V+ GA+ Sbjct: 221 TLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGAN 278 >gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens] Length = 721 Score = 181 bits (459), Expect = 2e-45 Identities = 100/228 (43%), Positives = 142/228 (62%), Gaps = 10/228 (4%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVN-ENCELKI 59 ME+DL ++ PL EH R F+YQLLRGLKY+HSA V+HRDLKP+NL +N E+ LKI Sbjct: 111 METDLANVLEQG-PLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKI 169 Query: 60 GDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR 119 GDFG+AR + H+ ++E + T+WYR+P L+LS + YT+AID+W+ GCIF EML Sbjct: 170 GDFGLAR-IMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTG 228 Query: 120 RQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAER---VRAYIQSLPPRQPVPWETVYPG 176 + LF G + + Q+QLI+ + P V + E + YI++ P + PG Sbjct: 229 KTLFAGAHELEQMQLILESI----PVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPG 284 Query: 177 ADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPF 224 R+AL L ++L F P R++A AL HP+++ Y P DEP + PF Sbjct: 285 ISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPMDEPISSHPF 332 >gi|21237739 mitogen-activated protein kinase 9 isoform JNK2 alpha1 [Homo sapiens] Length = 382 Score = 179 bits (455), Expect = 6e-45 Identities = 107/282 (37%), Positives = 163/282 (57%), Gaps = 28/282 (9%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M+++L Q+IH L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI Sbjct: 111 MDANLCQVIHME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR CT+ + MT YV TR+YRAPE++L + Y + +D+WSVGCI GE++ Sbjct: 169 DFGLARTACTN-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGELVKGC 222 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176 +F G +++ Q ++ LGTPS ++ + VR Y+++ P + +E ++P Sbjct: 223 VIFQGTDHIDQWNKVIEQLGTPSAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFP 281 Query: 177 --------ADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226 QA LL +ML +P RIS ALRHP++ ++DP E + PP +D Sbjct: 282 SESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDP-AEAEAPPPQIYDA 340 Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPSLQ 267 + E KE I E+ D+ R + G+ ++ QPS Q Sbjct: 341 QLEEREHAIEEWKELIYKEVMDWEERSKNGV---VKDQPSAQ 379 >gi|21237736 mitogen-activated protein kinase 9 isoform JNK2 alpha2 [Homo sapiens] Length = 424 Score = 179 bits (454), Expect = 7e-45 Identities = 108/286 (37%), Positives = 165/286 (57%), Gaps = 28/286 (9%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M+++L Q+IH L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI Sbjct: 111 MDANLCQVIHME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR CT+ + MT YV TR+YRAPE++L + Y + +D+WSVGCI GE++ Sbjct: 169 DFGLARTACTN-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGELVKGC 222 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176 +F G +++ Q ++ LGTPS ++ + VR Y+++ P + +E ++P Sbjct: 223 VIFQGTDHIDQWNKVIEQLGTPSAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFP 281 Query: 177 --------ADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226 QA LL +ML +P RIS ALRHP++ ++DP E + PP +D Sbjct: 282 SESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDP-AEAEAPPPQIYDA 340 Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPSLQPVAS 271 + E KE I E+ D+ R + G+ ++ QPS V+S Sbjct: 341 QLEEREHAIEEWKELIYKEVMDWEERSKNGV---VKDQPSDAAVSS 383 >gi|20986521 mitogen-activated protein kinase 8 isoform JNK1 beta2 [Homo sapiens] Length = 427 Score = 177 bits (448), Expect = 4e-44 Identities = 113/280 (40%), Positives = 161/280 (57%), Gaps = 28/280 (10%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M+++L Q+I L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI Sbjct: 111 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR TS + MT YV TR+YRAPE++L + Y + +D+WSVGCI GEM+ Sbjct: 169 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGEMIKGG 222 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176 LFPG +++ Q ++ LGTP P ++ + VR Y+++ P +E ++P Sbjct: 223 VLFPGTDHIDQWNKVIEQLGTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFP 281 Query: 177 AD--------RQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPF--DF 226 AD QA LL +ML + S RIS AL+HP++ ++DP E + PP D Sbjct: 282 ADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDP-SEAEAPPPKIPDK 340 Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265 D T E KE I E+ D R + G+ IR QPS Sbjct: 341 QLDEREHTIEEWKELIYKEVMDLEERTKNGV---IRGQPS 377 >gi|20986519 mitogen-activated protein kinase 8 isoform JNK1 beta1 [Homo sapiens] Length = 384 Score = 177 bits (448), Expect = 4e-44 Identities = 113/280 (40%), Positives = 161/280 (57%), Gaps = 28/280 (10%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M+++L Q+I L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI Sbjct: 111 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR TS + MT YV TR+YRAPE++L + Y + +D+WSVGCI GEM+ Sbjct: 169 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGEMIKGG 222 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176 LFPG +++ Q ++ LGTP P ++ + VR Y+++ P +E ++P Sbjct: 223 VLFPGTDHIDQWNKVIEQLGTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFP 281 Query: 177 AD--------RQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPF--DF 226 AD QA LL +ML + S RIS AL+HP++ ++DP E + PP D Sbjct: 282 ADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDP-SEAEAPPPKIPDK 340 Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265 D T E KE I E+ D R + G+ IR QPS Sbjct: 341 QLDEREHTIEEWKELIYKEVMDLEERTKNGV---IRGQPS 377 >gi|4506081 mitogen-activated protein kinase 10 isoform 1 [Homo sapiens] Length = 422 Score = 176 bits (447), Expect = 5e-44 Identities = 107/280 (38%), Positives = 164/280 (58%), Gaps = 28/280 (10%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M+++L Q+I L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI Sbjct: 149 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 206 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR TS + MT YV TR+YRAPE++L + Y + +D+WSVGCI GEM+ + Sbjct: 207 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGEMVRHK 260 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGA--- 177 LFPG++Y+ Q ++ LGTP P ++ + VR Y+++ P + + ++P + Sbjct: 261 ILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRNYVENRPKYAGLTFPKLFPDSLFP 319 Query: 178 ---------DRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226 QA LL +ML +P+ RIS AL+HP++ ++DP E + PP +D Sbjct: 320 ADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDP-AEVEAPPPQIYDK 378 Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265 D T E KE I E+ + + + G+ ++ QPS Sbjct: 379 QLDEREHTIEEWKELIYKEVMNSEEKTKNGV---VKGQPS 415 >gi|20986510 mitogen-activated protein kinase 10 isoform 2 [Homo sapiens] Length = 464 Score = 176 bits (447), Expect = 5e-44 Identities = 107/280 (38%), Positives = 164/280 (58%), Gaps = 28/280 (10%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M+++L Q+I L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI Sbjct: 149 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 206 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR TS + MT YV TR+YRAPE++L + Y + +D+WSVGCI GEM+ + Sbjct: 207 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGEMVRHK 260 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGA--- 177 LFPG++Y+ Q ++ LGTP P ++ + VR Y+++ P + + ++P + Sbjct: 261 ILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRNYVENRPKYAGLTFPKLFPDSLFP 319 Query: 178 ---------DRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226 QA LL +ML +P+ RIS AL+HP++ ++DP E + PP +D Sbjct: 320 ADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDP-AEVEAPPPQIYDK 378 Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265 D T E KE I E+ + + + G+ ++ QPS Sbjct: 379 QLDEREHTIEEWKELIYKEVMNSEEKTKNGV---VKGQPS 415 >gi|20986508 mitogen-activated protein kinase 10 isoform 4 [Homo sapiens] Length = 277 Score = 176 bits (447), Expect = 5e-44 Identities = 107/280 (38%), Positives = 164/280 (58%), Gaps = 28/280 (10%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M+++L Q+I L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI Sbjct: 4 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 61 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR TS + MT YV TR+YRAPE++L + Y + +D+WSVGCI GEM+ + Sbjct: 62 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGEMVRHK 115 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGA--- 177 LFPG++Y+ Q ++ LGTP P ++ + VR Y+++ P + + ++P + Sbjct: 116 ILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRNYVENRPKYAGLTFPKLFPDSLFP 174 Query: 178 ---------DRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226 QA LL +ML +P+ RIS AL+HP++ ++DP E + PP +D Sbjct: 175 ADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDP-AEVEAPPPQIYDK 233 Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265 D T E KE I E+ + + + G+ ++ QPS Sbjct: 234 QLDEREHTIEEWKELIYKEVMNSEEKTKNGV---VKGQPS 270 >gi|20986506 mitogen-activated protein kinase 10 isoform 3 [Homo sapiens] Length = 426 Score = 176 bits (447), Expect = 5e-44 Identities = 107/280 (38%), Positives = 164/280 (58%), Gaps = 28/280 (10%) Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60 M+++L Q+I L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI Sbjct: 111 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168 Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120 DFG+AR TS + MT YV TR+YRAPE++L + Y + +D+WSVGCI GEM+ + Sbjct: 169 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGEMVRHK 222 Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGA--- 177 LFPG++Y+ Q ++ LGTP P ++ + VR Y+++ P + + ++P + Sbjct: 223 ILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRNYVENRPKYAGLTFPKLFPDSLFP 281 Query: 178 ---------DRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226 QA LL +ML +P+ RIS AL+HP++ ++DP E + PP +D Sbjct: 282 ADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDP-AEVEAPPPQIYDK 340 Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265 D T E KE I E+ + + + G+ ++ QPS Sbjct: 341 QLDEREHTIEEWKELIYKEVMNSEEKTKNGV---VKGQPS 377 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.134 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 38,081,012 Number of Sequences: 37866 Number of extensions: 2972365 Number of successful extensions: 94079 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 2147 Number of HSP's successfully gapped in prelim test: 2354 Number of HSP's that attempted gapping in prelim test: 20373 Number of HSP's gapped (non-prelim): 33314 length of query: 677 length of database: 18,247,518 effective HSP length: 109 effective length of query: 568 effective length of database: 14,120,124 effective search space: 8020230432 effective search space used: 8020230432 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.