Guide to the Human Genome
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Search of human proteins with 20986499

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo
sapiens]
         (677 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s...  1389   0.0  
gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ...  1389   0.0  
gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ...  1389   0.0  
gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo s...  1389   0.0  
gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo s...   268   1e-71
gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens]         262   7e-70
gi|66932916 mitogen-activated protein kinase 1 [Homo sapiens]         262   7e-70
gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo s...   246   5e-65
gi|20128774 mitogen-activated protein kinase 11 [Homo sapiens]        246   5e-65
gi|20986512 mitogen-activated protein kinase 14 isoform 2 [Homo ...   231   2e-60
gi|4503069 mitogen-activated protein kinase 14 isoform 1 [Homo s...   228   2e-59
gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens]         220   4e-57
gi|158138507 mitogen-activated protein kinase 3 isoform 3 [Homo ...   218   1e-56
gi|149408126 nemo like kinase [Homo sapiens]                          206   4e-53
gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens]        201   2e-51
gi|48255970 mitogen-activated protein kinase 12 [Homo sapiens]        192   1e-48
gi|21237742 mitogen-activated protein kinase 9 isoform JNK2 beta...   188   2e-47
gi|21237745 mitogen-activated protein kinase 9 isoform JNK2 beta...   187   2e-47
gi|20986523 mitogen-activated protein kinase 8 isoform JNK1 alph...   182   7e-46
gi|4506095 mitogen-activated protein kinase 8 isoform JNK1 alpha...   182   7e-46
gi|20986514 mitogen-activated protein kinase 14 isoform 3 [Homo ...   182   7e-46
gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens]          181   2e-45
gi|21237739 mitogen-activated protein kinase 9 isoform JNK2 alph...   179   6e-45
gi|21237736 mitogen-activated protein kinase 9 isoform JNK2 alph...   179   7e-45
gi|20986521 mitogen-activated protein kinase 8 isoform JNK1 beta...   177   4e-44
gi|20986519 mitogen-activated protein kinase 8 isoform JNK1 beta...   177   4e-44
gi|4506081 mitogen-activated protein kinase 10 isoform 1 [Homo s...   176   5e-44
gi|20986510 mitogen-activated protein kinase 10 isoform 2 [Homo ...   176   5e-44
gi|20986508 mitogen-activated protein kinase 10 isoform 4 [Homo ...   176   5e-44
gi|20986506 mitogen-activated protein kinase 10 isoform 3 [Homo ...   176   5e-44

>gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score = 1389 bits (3596), Expect = 0.0
 Identities = 677/677 (100%), Positives = 677/677 (100%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG
Sbjct: 140 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 199

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR
Sbjct: 200 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 259

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
           QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ
Sbjct: 260 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 319

Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
           ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE
Sbjct: 320 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 379

Query: 241 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 300
           AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP
Sbjct: 380 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 439

Query: 301 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 360
           PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL
Sbjct: 440 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 499

Query: 361 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 420
           EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL
Sbjct: 500 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 559

Query: 421 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 480
           VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ
Sbjct: 560 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 619

Query: 481 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 540
           SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS
Sbjct: 620 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 679

Query: 541 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 600
           TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA
Sbjct: 680 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 739

Query: 601 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 660
           GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI
Sbjct: 740 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 799

Query: 661 QMDSPMLLADLPDLQDP 677
           QMDSPMLLADLPDLQDP
Sbjct: 800 QMDSPMLLADLPDLQDP 816


>gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score = 1389 bits (3596), Expect = 0.0
 Identities = 677/677 (100%), Positives = 677/677 (100%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG
Sbjct: 140 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 199

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR
Sbjct: 200 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 259

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
           QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ
Sbjct: 260 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 319

Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
           ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE
Sbjct: 320 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 379

Query: 241 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 300
           AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP
Sbjct: 380 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 439

Query: 301 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 360
           PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL
Sbjct: 440 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 499

Query: 361 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 420
           EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL
Sbjct: 500 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 559

Query: 421 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 480
           VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ
Sbjct: 560 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 619

Query: 481 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 540
           SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS
Sbjct: 620 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 679

Query: 541 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 600
           TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA
Sbjct: 680 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 739

Query: 601 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 660
           GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI
Sbjct: 740 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 799

Query: 661 QMDSPMLLADLPDLQDP 677
           QMDSPMLLADLPDLQDP
Sbjct: 800 QMDSPMLLADLPDLQDP 816


>gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score = 1389 bits (3596), Expect = 0.0
 Identities = 677/677 (100%), Positives = 677/677 (100%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG
Sbjct: 140 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 199

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR
Sbjct: 200 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 259

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
           QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ
Sbjct: 260 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 319

Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
           ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE
Sbjct: 320 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 379

Query: 241 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 300
           AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP
Sbjct: 380 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 439

Query: 301 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 360
           PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL
Sbjct: 440 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 499

Query: 361 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 420
           EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL
Sbjct: 500 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 559

Query: 421 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 480
           VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ
Sbjct: 560 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 619

Query: 481 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 540
           SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS
Sbjct: 620 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 679

Query: 541 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 600
           TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA
Sbjct: 680 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 739

Query: 601 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 660
           GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI
Sbjct: 740 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 799

Query: 661 QMDSPMLLADLPDLQDP 677
           QMDSPMLLADLPDLQDP
Sbjct: 800 QMDSPMLLADLPDLQDP 816


>gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo
           sapiens]
          Length = 677

 Score = 1389 bits (3596), Expect = 0.0
 Identities = 677/677 (100%), Positives = 677/677 (100%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG
Sbjct: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR
Sbjct: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
           QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ
Sbjct: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180

Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
           ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE
Sbjct: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240

Query: 241 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 300
           AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP
Sbjct: 241 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 300

Query: 301 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 360
           PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL
Sbjct: 301 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 360

Query: 361 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 420
           EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL
Sbjct: 361 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 420

Query: 421 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 480
           VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ
Sbjct: 421 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 480

Query: 481 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 540
           SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS
Sbjct: 481 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 540

Query: 541 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 600
           TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA
Sbjct: 541 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 600

Query: 601 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 660
           GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI
Sbjct: 601 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 660

Query: 661 QMDSPMLLADLPDLQDP 677
           QMDSPMLLADLPDLQDP
Sbjct: 661 QMDSPMLLADLPDLQDP 677


>gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo
           sapiens]
          Length = 379

 Score =  268 bits (685), Expect = 1e-71
 Identities = 130/249 (52%), Positives = 177/249 (71%), Gaps = 2/249 (0%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           ME+DL++++ S Q L+ +H+ YFLYQ+LRGLKY+HSA V+HRDLKPSNLL+N  C+LKI 
Sbjct: 125 METDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKIC 183

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR +     +H  F+TEYVATRWYRAPE+ML+   YT++ID+WSVGCI  EML+ R
Sbjct: 184 DFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 242

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
            +FPGK+Y+ QL  I+ +LG+PS   +  +   + R Y+QSLP +  V W  ++P +D +
Sbjct: 243 PIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSK 302

Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
           AL LL RML F P+ RI+   AL HP+L +Y+DP DEP    PF FA + + L +ER+KE
Sbjct: 303 ALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKE 362

Query: 241 AIVAEIEDF 249
            I  E   F
Sbjct: 363 LIFQETARF 371


>gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens]
          Length = 360

 Score =  262 bits (670), Expect = 7e-70
 Identities = 127/249 (51%), Positives = 174/249 (69%), Gaps = 2/249 (0%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           ME+DL++++  +Q L+ +H+ YFLYQ+LRGLKY+HSA V+HRDLKPSNLL+N  C+LKI 
Sbjct: 108 METDLYKLL-KTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKIC 166

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR +     +H  F+TEYVATRWYRAPE+ML+   YT++ID+WSVGCI  EML+ R
Sbjct: 167 DFGLAR-VADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 225

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
            +FPGK+Y+ QL  I+ +LG+PS   +  +   + R Y+ SLP +  VPW  ++P AD +
Sbjct: 226 PIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSK 285

Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
           AL LL +ML F P  RI    AL HP+L +Y+DP DEP    PF F  + + L +E++KE
Sbjct: 286 ALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKE 345

Query: 241 AIVAEIEDF 249
            I  E   F
Sbjct: 346 LIFEETARF 354


>gi|66932916 mitogen-activated protein kinase 1 [Homo sapiens]
          Length = 360

 Score =  262 bits (670), Expect = 7e-70
 Identities = 127/249 (51%), Positives = 174/249 (69%), Gaps = 2/249 (0%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           ME+DL++++  +Q L+ +H+ YFLYQ+LRGLKY+HSA V+HRDLKPSNLL+N  C+LKI 
Sbjct: 108 METDLYKLL-KTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKIC 166

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR +     +H  F+TEYVATRWYRAPE+ML+   YT++ID+WSVGCI  EML+ R
Sbjct: 167 DFGLAR-VADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 225

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
            +FPGK+Y+ QL  I+ +LG+PS   +  +   + R Y+ SLP +  VPW  ++P AD +
Sbjct: 226 PIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSK 285

Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
           AL LL +ML F P  RI    AL HP+L +Y+DP DEP    PF F  + + L +E++KE
Sbjct: 286 ALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKE 345

Query: 241 AIVAEIEDF 249
            I  E   F
Sbjct: 346 LIFEETARF 354


>gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo
           sapiens]
          Length = 357

 Score =  246 bits (628), Expect = 5e-65
 Identities = 118/222 (53%), Positives = 162/222 (72%), Gaps = 2/222 (0%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           ME+DL++++ S Q L+ +H+ YFLYQ+LRGLKY+HSA V+HRDLKPSNLL+N  C+LKI 
Sbjct: 125 METDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKIC 183

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR +     +H  F+TEYVATRWYRAPE+ML+   YT++ID+WSVGCI  EML+ R
Sbjct: 184 DFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 242

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
            +FPGK+Y+ QL  I+ +LG+PS   +  +   + R Y+QSLP +  V W  ++P +D +
Sbjct: 243 PIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSK 302

Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAP 222
           AL LL RML F P+ RI+   AL HP+L +Y+DP DE   +P
Sbjct: 303 ALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEVGQSP 344


>gi|20128774 mitogen-activated protein kinase 11 [Homo sapiens]
          Length = 364

 Score =  246 bits (628), Expect = 5e-65
 Identities = 126/249 (50%), Positives = 171/249 (68%), Gaps = 9/249 (3%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M +DL+ I+   Q L+ EHV++ +YQLLRGLKY+HSA +IHRDLKPSN+ VNE+CEL+I 
Sbjct: 109 MGADLNNIV-KCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRIL 167

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR      A+ +  MT YVATRWYRAPE+ML+   Y Q +D+WSVGCI  E+L  +
Sbjct: 168 DFGLAR-----QADEE--MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGK 220

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
            LFPG +Y+ QL+ IM V+GTPSP V+  + +E  R YIQSLPP       +++ GA+  
Sbjct: 221 ALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPL 280

Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
           A+ LLGRML  +   R+SAA AL H + ++YHDP+DEP+ A P+D + + +  T E  KE
Sbjct: 281 AIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPE-AEPYDESVEAKERTLEEWKE 339

Query: 241 AIVAEIEDF 249
               E+  F
Sbjct: 340 LTYQEVLSF 348


>gi|20986512 mitogen-activated protein kinase 14 isoform 2 [Homo
           sapiens]
          Length = 360

 Score =  231 bits (588), Expect = 2e-60
 Identities = 120/249 (48%), Positives = 164/249 (65%), Gaps = 9/249 (3%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M +DL+ I+   Q LT +HV++ +YQ+LRGLKY+HSA +IHRDLKPSNL VNE+CELKI 
Sbjct: 109 MGADLNNIV-KCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKIL 167

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR            MT YVATRWYRAPE+ML+   Y Q +D+WSVGCI  E+L  R
Sbjct: 168 DFGLARHTDDE-------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGR 220

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
            LFPG +++ QL+LI+ ++GTP   +++ + +E  R YIQSL     + +  V+ GA+  
Sbjct: 221 TLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPL 280

Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
           A+ LL +ML  +   RI+AA AL H + A+YHDPDDEP  A P+D +F+   L  +  K 
Sbjct: 281 AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEP-VADPYDQSFESRDLLIDEWKS 339

Query: 241 AIVAEIEDF 249
               E+  F
Sbjct: 340 LTYDEVISF 348


>gi|4503069 mitogen-activated protein kinase 14 isoform 1 [Homo
           sapiens]
          Length = 360

 Score =  228 bits (580), Expect = 2e-59
 Identities = 121/249 (48%), Positives = 161/249 (64%), Gaps = 9/249 (3%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M +DL+ I+   Q LT +HV++ +YQ+LRGLKY+HSA +IHRDLKPSNL VNE+CELKI 
Sbjct: 109 MGADLNNIV-KCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKIL 167

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR            MT YVATRWYRAPE+ML+   Y Q +D+WSVGCI  E+L  R
Sbjct: 168 DFGLARHTDDE-------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGR 220

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
            LFPG ++++QLQ IM + GTP   +I  + +   R YIQSL     + +  V+ GA+  
Sbjct: 221 TLFPGTDHINQLQQIMRLTGTPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPL 280

Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
           A+ LL +ML  +   RI+AA AL H + A+YHDPDDEP  A P+D +F+   L  +  K 
Sbjct: 281 AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEP-VADPYDQSFESRDLLIDEWKS 339

Query: 241 AIVAEIEDF 249
               E+  F
Sbjct: 340 LTYDEVISF 348


>gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens]
          Length = 365

 Score =  220 bits (560), Expect = 4e-57
 Identities = 117/260 (45%), Positives = 164/260 (63%), Gaps = 11/260 (4%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M++DL +I+      + E ++Y +YQ+L+GLKY+HSA V+HRDLKP NL VNE+CELKI 
Sbjct: 110 MQTDLQKIM--GMEFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKIL 167

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR    + AE    MT YV TRWYRAPE++LS   Y Q +D+WSVGCI  EML  +
Sbjct: 168 DFGLARH---ADAE----MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGK 220

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
            LF GK+Y+ QL  I+ V G P    +Q +  +  ++YIQSLP      +  ++P A  Q
Sbjct: 221 TLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQSLPQTPRKDFTQLFPRASPQ 280

Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
           A  LL +ML  +   R++AA AL HPF   + DP++E +   PFD + + E LT +  K+
Sbjct: 281 AADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQQPFDDSLEHEKLTVDEWKQ 340

Query: 241 AIVAEIEDFH--ARREGIRQ 258
            I  EI +F   AR++  R+
Sbjct: 341 HIYKEIVNFSPIARKDSRRR 360


>gi|158138507 mitogen-activated protein kinase 3 isoform 3 [Homo
           sapiens]
          Length = 335

 Score =  218 bits (555), Expect = 1e-56
 Identities = 116/249 (46%), Positives = 152/249 (61%), Gaps = 46/249 (18%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           ME+DL++++ S Q L+ +H+ YFLYQ+LRGLKY+HSA V+HRDLKPSNLL+N  C+LKI 
Sbjct: 125 METDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKIC 183

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR +     +H  F+TEYVATRWYRAPE+ML+   YT++ID+WSVGCI  EML+ R
Sbjct: 184 DFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 242

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
            +FPGK+Y+ QL  I+                                            
Sbjct: 243 PIFPGKHYLDQLNHIL-------------------------------------------- 258

Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
           AL LL RML F P+ RI+   AL HP+L +Y+DP DEP    PF FA + + L +ER+KE
Sbjct: 259 ALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKE 318

Query: 241 AIVAEIEDF 249
            I  E   F
Sbjct: 319 LIFQETARF 327


>gi|149408126 nemo like kinase [Homo sapiens]
          Length = 527

 Score =  206 bits (525), Expect = 4e-53
 Identities = 120/264 (45%), Positives = 162/264 (61%), Gaps = 26/264 (9%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M+SDLH+II S QPL+ +HV+ FLYQ+LRGLKY+HSA ++HRD+KP NLLVN NC LKI 
Sbjct: 222 MQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKIC 281

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR       +    MT+ V T++YRAPE+++    Y+ AID+WSVGCIF E+L RR
Sbjct: 282 DFGLAR---VEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRR 338

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQP-VP-WETVYPGAD 178
            LF  ++ + QL LI  +LGTPS   ++    E  +A+I   P +QP +P   T+   A 
Sbjct: 339 ILFQAQSPIQQLDLITDLLGTPSLEAMR-TACEGAKAHILRGPHKQPSLPVLYTLSSQAT 397

Query: 179 RQALSLLGRMLRFEPSARISAAAALRHPFL----AKYH----------------DPDDEP 218
            +A+ LL RML F+PS RISA  AL HP+L     +YH                  D EP
Sbjct: 398 HEAVHLLCRMLVFDPSKRISAKDALAHPYLDEGRLRYHTCMCKCCFSTSTGRVYTSDFEP 457

Query: 219 DCAPPFDFAFDREALTRERIKEAI 242
              P FD  F++   +  ++KE I
Sbjct: 458 VTNPKFDDTFEKNLSSVRQVKEII 481


>gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens]
          Length = 544

 Score =  201 bits (510), Expect = 2e-51
 Identities = 130/354 (36%), Positives = 183/354 (51%), Gaps = 33/354 (9%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M++DL+ +I     L   HVR   YQLLR  +++HS  V+HRD KPSN+L++ NC +K+ 
Sbjct: 95  MDTDLNAVIRKGGLLQDVHVRSIFYQLLRATRFLHSGHVVHRDQKPSNVLLDANCTVKLC 154

Query: 61  DFGMARGLCTSP-AEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR 119
           DFG+AR L   P       +TEYVATRWYRAPE++LS H YT  +D+WS+GCI GEML  
Sbjct: 155 DFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEVLLSSHRYTLGVDMWSLGCILGEMLRG 214

Query: 120 RQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSL--PPRQPVPWETVYPGA 177
           R LFPG + +HQL+LI+  +  PS   + A+G+    + +  L   PRQ +    + P  
Sbjct: 215 RPLFPGTSTLHQLELILETIPPPSEEDLLALGSGCRASVLHQLGSRPRQTLD-ALLPPDT 273

Query: 178 DRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRER 237
             +AL LL R+L F P  R+SA  AL+HP++ ++H P DE          + REA  R R
Sbjct: 274 SPEALDLLRRLLVFAPDKRLSATQALQHPYVQRFHCPSDE----------WAREADVRPR 323

Query: 238 IKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSP---WAPSGDCAMES 294
             E +   + ++ +R   + Q I         + E G P+   PS      P  D  + S
Sbjct: 324 AHEGVQLSVPEYRSR---VYQMILECGGSSGTSREKG-PEGVSPSQAHLHKPRADPQLPS 379

Query: 295 PPPAPPPCPGPAPDTIDLTLQPPP---PVSEPAPPKKDGAISDNTKAALKAALL 345
             P   P P P         Q  P   P    +P         N+   L+ ALL
Sbjct: 380 RTPVQGPRPRP---------QSSPGHDPAEHESPRAAKNVPRQNSAPLLQTALL 424


>gi|48255970 mitogen-activated protein kinase 12 [Homo sapiens]
          Length = 367

 Score =  192 bits (487), Expect = 1e-48
 Identities = 99/254 (38%), Positives = 153/254 (60%), Gaps = 9/254 (3%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M +DL +++   + L  + +++ +YQ+L+GL+Y+H+A +IHRDLKP NL VNE+CELKI 
Sbjct: 112 MGTDLGKLM-KHEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKIL 170

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR   +        MT YV TRWYRAPE++L+   YTQ +D+WSVGCI  EM+  +
Sbjct: 171 DFGLARQADSE-------MTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGK 223

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
            LF G +++ QL+ IM V GTP    +Q + ++  + Y++ LP  +   + ++   A   
Sbjct: 224 TLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASILTNASPL 283

Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
           A++LL +ML  +   R++A  AL HP+    HD +DEP     +D +FD    T +  K 
Sbjct: 284 AVNLLEKMLVLDAEQRVTAGEALAHPYFESLHDTEDEPQ-VQKYDDSFDDVDRTLDEWKR 342

Query: 241 AIVAEIEDFHARRE 254
               E+  F   R+
Sbjct: 343 VTYKEVLSFKPPRQ 356


>gi|21237742 mitogen-activated protein kinase 9 isoform JNK2 beta1
           [Homo sapiens]
          Length = 382

 Score =  188 bits (477), Expect = 2e-47
 Identities = 110/282 (39%), Positives = 165/282 (58%), Gaps = 28/282 (9%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M+++L Q+IH    L  E + Y LYQ+L G+K++HSA +IHRDLKPSN++V  +C LKI 
Sbjct: 111 MDANLCQVIHME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR  CT+     + MT YV TR+YRAPE++L +  Y + +D+WSVGCI  EM+  +
Sbjct: 169 DFGLARTACTN-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMAEMVLHK 222

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176
            LFPG++Y+ Q   ++  LGTPS   ++ +    VR Y+++ P    + +E ++P     
Sbjct: 223 VLFPGRDYIDQWNKVIEQLGTPSAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFP 281

Query: 177 --------ADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226
                      QA  LL +ML  +P  RIS   ALRHP++  ++DP  E +  PP  +D 
Sbjct: 282 SESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDP-AEAEAPPPQIYDA 340

Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPSLQ 267
             +      E  KE I  E+ D+  R + G+   ++ QPS Q
Sbjct: 341 QLEEREHAIEEWKELIYKEVMDWEERSKNGV---VKDQPSAQ 379


>gi|21237745 mitogen-activated protein kinase 9 isoform JNK2 beta2
           [Homo sapiens]
          Length = 424

 Score =  187 bits (476), Expect = 2e-47
 Identities = 111/286 (38%), Positives = 167/286 (58%), Gaps = 28/286 (9%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M+++L Q+IH    L  E + Y LYQ+L G+K++HSA +IHRDLKPSN++V  +C LKI 
Sbjct: 111 MDANLCQVIHME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR  CT+     + MT YV TR+YRAPE++L +  Y + +D+WSVGCI  EM+  +
Sbjct: 169 DFGLARTACTN-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMAEMVLHK 222

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176
            LFPG++Y+ Q   ++  LGTPS   ++ +    VR Y+++ P    + +E ++P     
Sbjct: 223 VLFPGRDYIDQWNKVIEQLGTPSAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFP 281

Query: 177 --------ADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226
                      QA  LL +ML  +P  RIS   ALRHP++  ++DP  E +  PP  +D 
Sbjct: 282 SESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDP-AEAEAPPPQIYDA 340

Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPSLQPVAS 271
             +      E  KE I  E+ D+  R + G+   ++ QPS   V+S
Sbjct: 341 QLEEREHAIEEWKELIYKEVMDWEERSKNGV---VKDQPSDAAVSS 383


>gi|20986523 mitogen-activated protein kinase 8 isoform JNK1 alpha2
           [Homo sapiens]
          Length = 427

 Score =  182 bits (463), Expect = 7e-46
 Identities = 115/280 (41%), Positives = 163/280 (58%), Gaps = 28/280 (10%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M+++L Q+I     L  E + Y LYQ+L G+K++HSA +IHRDLKPSN++V  +C LKI 
Sbjct: 111 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR   TS     + MT YV TR+YRAPE++L +  Y + +DLWSVGCI GEM+  +
Sbjct: 169 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDLWSVGCIMGEMVCHK 222

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176
            LFPG++Y+ Q   ++  LGTP P  ++ +    VR Y+++ P      +E ++P     
Sbjct: 223 ILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFP 281

Query: 177 AD--------RQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPF--DF 226
           AD         QA  LL +ML  + S RIS   AL+HP++  ++DP  E +  PP   D 
Sbjct: 282 ADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDP-SEAEAPPPKIPDK 340

Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265
             D    T E  KE I  E+ D   R + G+   IR QPS
Sbjct: 341 QLDEREHTIEEWKELIYKEVMDLEERTKNGV---IRGQPS 377


>gi|4506095 mitogen-activated protein kinase 8 isoform JNK1 alpha1
           [Homo sapiens]
          Length = 384

 Score =  182 bits (463), Expect = 7e-46
 Identities = 115/280 (41%), Positives = 163/280 (58%), Gaps = 28/280 (10%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M+++L Q+I     L  E + Y LYQ+L G+K++HSA +IHRDLKPSN++V  +C LKI 
Sbjct: 111 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR   TS     + MT YV TR+YRAPE++L +  Y + +DLWSVGCI GEM+  +
Sbjct: 169 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDLWSVGCIMGEMVCHK 222

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176
            LFPG++Y+ Q   ++  LGTP P  ++ +    VR Y+++ P      +E ++P     
Sbjct: 223 ILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFP 281

Query: 177 AD--------RQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPF--DF 226
           AD         QA  LL +ML  + S RIS   AL+HP++  ++DP  E +  PP   D 
Sbjct: 282 ADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDP-SEAEAPPPKIPDK 340

Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265
             D    T E  KE I  E+ D   R + G+   IR QPS
Sbjct: 341 QLDEREHTIEEWKELIYKEVMDLEERTKNGV---IRGQPS 377


>gi|20986514 mitogen-activated protein kinase 14 isoform 3 [Homo
           sapiens]
          Length = 297

 Score =  182 bits (463), Expect = 7e-46
 Identities = 91/178 (51%), Positives = 124/178 (69%), Gaps = 8/178 (4%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M +DL+ I+   Q LT +HV++ +YQ+LRGLKY+HSA +IHRDLKPSNL VNE+CELKI 
Sbjct: 109 MGADLNNIV-KCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKIL 167

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR            MT YVATRWYRAPE+ML+   Y Q +D+WSVGCI  E+L  R
Sbjct: 168 DFGLARHTDDE-------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGR 220

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGAD 178
            LFPG +++ QL+LI+ ++GTP   +++ + +E  R YIQSL     + +  V+ GA+
Sbjct: 221 TLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGAN 278


>gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens]
          Length = 721

 Score =  181 bits (459), Expect = 2e-45
 Identities = 100/228 (43%), Positives = 142/228 (62%), Gaps = 10/228 (4%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVN-ENCELKI 59
           ME+DL  ++    PL  EH R F+YQLLRGLKY+HSA V+HRDLKP+NL +N E+  LKI
Sbjct: 111 METDLANVLEQG-PLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKI 169

Query: 60  GDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR 119
           GDFG+AR +      H+  ++E + T+WYR+P L+LS + YT+AID+W+ GCIF EML  
Sbjct: 170 GDFGLAR-IMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTG 228

Query: 120 RQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAER---VRAYIQSLPPRQPVPWETVYPG 176
           + LF G + + Q+QLI+  +    P V +    E    +  YI++       P   + PG
Sbjct: 229 KTLFAGAHELEQMQLILESI----PVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPG 284

Query: 177 ADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPF 224
             R+AL  L ++L F P  R++A  AL HP+++ Y  P DEP  + PF
Sbjct: 285 ISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPMDEPISSHPF 332


>gi|21237739 mitogen-activated protein kinase 9 isoform JNK2 alpha1
           [Homo sapiens]
          Length = 382

 Score =  179 bits (455), Expect = 6e-45
 Identities = 107/282 (37%), Positives = 163/282 (57%), Gaps = 28/282 (9%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M+++L Q+IH    L  E + Y LYQ+L G+K++HSA +IHRDLKPSN++V  +C LKI 
Sbjct: 111 MDANLCQVIHME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR  CT+     + MT YV TR+YRAPE++L +  Y + +D+WSVGCI GE++   
Sbjct: 169 DFGLARTACTN-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGELVKGC 222

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176
            +F G +++ Q   ++  LGTPS   ++ +    VR Y+++ P    + +E ++P     
Sbjct: 223 VIFQGTDHIDQWNKVIEQLGTPSAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFP 281

Query: 177 --------ADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226
                      QA  LL +ML  +P  RIS   ALRHP++  ++DP  E +  PP  +D 
Sbjct: 282 SESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDP-AEAEAPPPQIYDA 340

Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPSLQ 267
             +      E  KE I  E+ D+  R + G+   ++ QPS Q
Sbjct: 341 QLEEREHAIEEWKELIYKEVMDWEERSKNGV---VKDQPSAQ 379


>gi|21237736 mitogen-activated protein kinase 9 isoform JNK2 alpha2
           [Homo sapiens]
          Length = 424

 Score =  179 bits (454), Expect = 7e-45
 Identities = 108/286 (37%), Positives = 165/286 (57%), Gaps = 28/286 (9%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M+++L Q+IH    L  E + Y LYQ+L G+K++HSA +IHRDLKPSN++V  +C LKI 
Sbjct: 111 MDANLCQVIHME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR  CT+     + MT YV TR+YRAPE++L +  Y + +D+WSVGCI GE++   
Sbjct: 169 DFGLARTACTN-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGELVKGC 222

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176
            +F G +++ Q   ++  LGTPS   ++ +    VR Y+++ P    + +E ++P     
Sbjct: 223 VIFQGTDHIDQWNKVIEQLGTPSAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFP 281

Query: 177 --------ADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226
                      QA  LL +ML  +P  RIS   ALRHP++  ++DP  E +  PP  +D 
Sbjct: 282 SESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDP-AEAEAPPPQIYDA 340

Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPSLQPVAS 271
             +      E  KE I  E+ D+  R + G+   ++ QPS   V+S
Sbjct: 341 QLEEREHAIEEWKELIYKEVMDWEERSKNGV---VKDQPSDAAVSS 383


>gi|20986521 mitogen-activated protein kinase 8 isoform JNK1 beta2
           [Homo sapiens]
          Length = 427

 Score =  177 bits (448), Expect = 4e-44
 Identities = 113/280 (40%), Positives = 161/280 (57%), Gaps = 28/280 (10%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M+++L Q+I     L  E + Y LYQ+L G+K++HSA +IHRDLKPSN++V  +C LKI 
Sbjct: 111 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR   TS     + MT YV TR+YRAPE++L +  Y + +D+WSVGCI GEM+   
Sbjct: 169 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGEMIKGG 222

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176
            LFPG +++ Q   ++  LGTP P  ++ +    VR Y+++ P      +E ++P     
Sbjct: 223 VLFPGTDHIDQWNKVIEQLGTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFP 281

Query: 177 AD--------RQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPF--DF 226
           AD         QA  LL +ML  + S RIS   AL+HP++  ++DP  E +  PP   D 
Sbjct: 282 ADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDP-SEAEAPPPKIPDK 340

Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265
             D    T E  KE I  E+ D   R + G+   IR QPS
Sbjct: 341 QLDEREHTIEEWKELIYKEVMDLEERTKNGV---IRGQPS 377


>gi|20986519 mitogen-activated protein kinase 8 isoform JNK1 beta1
           [Homo sapiens]
          Length = 384

 Score =  177 bits (448), Expect = 4e-44
 Identities = 113/280 (40%), Positives = 161/280 (57%), Gaps = 28/280 (10%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M+++L Q+I     L  E + Y LYQ+L G+K++HSA +IHRDLKPSN++V  +C LKI 
Sbjct: 111 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR   TS     + MT YV TR+YRAPE++L +  Y + +D+WSVGCI GEM+   
Sbjct: 169 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGEMIKGG 222

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176
            LFPG +++ Q   ++  LGTP P  ++ +    VR Y+++ P      +E ++P     
Sbjct: 223 VLFPGTDHIDQWNKVIEQLGTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFP 281

Query: 177 AD--------RQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPF--DF 226
           AD         QA  LL +ML  + S RIS   AL+HP++  ++DP  E +  PP   D 
Sbjct: 282 ADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDP-SEAEAPPPKIPDK 340

Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265
             D    T E  KE I  E+ D   R + G+   IR QPS
Sbjct: 341 QLDEREHTIEEWKELIYKEVMDLEERTKNGV---IRGQPS 377


>gi|4506081 mitogen-activated protein kinase 10 isoform 1 [Homo
           sapiens]
          Length = 422

 Score =  176 bits (447), Expect = 5e-44
 Identities = 107/280 (38%), Positives = 164/280 (58%), Gaps = 28/280 (10%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M+++L Q+I     L  E + Y LYQ+L G+K++HSA +IHRDLKPSN++V  +C LKI 
Sbjct: 149 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 206

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR   TS     + MT YV TR+YRAPE++L +  Y + +D+WSVGCI GEM+  +
Sbjct: 207 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGEMVRHK 260

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGA--- 177
            LFPG++Y+ Q   ++  LGTP P  ++ +    VR Y+++ P    + +  ++P +   
Sbjct: 261 ILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRNYVENRPKYAGLTFPKLFPDSLFP 319

Query: 178 ---------DRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226
                      QA  LL +ML  +P+ RIS   AL+HP++  ++DP  E +  PP  +D 
Sbjct: 320 ADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDP-AEVEAPPPQIYDK 378

Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265
             D    T E  KE I  E+ +   + + G+   ++ QPS
Sbjct: 379 QLDEREHTIEEWKELIYKEVMNSEEKTKNGV---VKGQPS 415


>gi|20986510 mitogen-activated protein kinase 10 isoform 2 [Homo
           sapiens]
          Length = 464

 Score =  176 bits (447), Expect = 5e-44
 Identities = 107/280 (38%), Positives = 164/280 (58%), Gaps = 28/280 (10%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M+++L Q+I     L  E + Y LYQ+L G+K++HSA +IHRDLKPSN++V  +C LKI 
Sbjct: 149 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 206

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR   TS     + MT YV TR+YRAPE++L +  Y + +D+WSVGCI GEM+  +
Sbjct: 207 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGEMVRHK 260

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGA--- 177
            LFPG++Y+ Q   ++  LGTP P  ++ +    VR Y+++ P    + +  ++P +   
Sbjct: 261 ILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRNYVENRPKYAGLTFPKLFPDSLFP 319

Query: 178 ---------DRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226
                      QA  LL +ML  +P+ RIS   AL+HP++  ++DP  E +  PP  +D 
Sbjct: 320 ADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDP-AEVEAPPPQIYDK 378

Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265
             D    T E  KE I  E+ +   + + G+   ++ QPS
Sbjct: 379 QLDEREHTIEEWKELIYKEVMNSEEKTKNGV---VKGQPS 415


>gi|20986508 mitogen-activated protein kinase 10 isoform 4 [Homo
           sapiens]
          Length = 277

 Score =  176 bits (447), Expect = 5e-44
 Identities = 107/280 (38%), Positives = 164/280 (58%), Gaps = 28/280 (10%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M+++L Q+I     L  E + Y LYQ+L G+K++HSA +IHRDLKPSN++V  +C LKI 
Sbjct: 4   MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 61

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR   TS     + MT YV TR+YRAPE++L +  Y + +D+WSVGCI GEM+  +
Sbjct: 62  DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGEMVRHK 115

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGA--- 177
            LFPG++Y+ Q   ++  LGTP P  ++ +    VR Y+++ P    + +  ++P +   
Sbjct: 116 ILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRNYVENRPKYAGLTFPKLFPDSLFP 174

Query: 178 ---------DRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226
                      QA  LL +ML  +P+ RIS   AL+HP++  ++DP  E +  PP  +D 
Sbjct: 175 ADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDP-AEVEAPPPQIYDK 233

Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265
             D    T E  KE I  E+ +   + + G+   ++ QPS
Sbjct: 234 QLDEREHTIEEWKELIYKEVMNSEEKTKNGV---VKGQPS 270


>gi|20986506 mitogen-activated protein kinase 10 isoform 3 [Homo
           sapiens]
          Length = 426

 Score =  176 bits (447), Expect = 5e-44
 Identities = 107/280 (38%), Positives = 164/280 (58%), Gaps = 28/280 (10%)

Query: 1   MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
           M+++L Q+I     L  E + Y LYQ+L G+K++HSA +IHRDLKPSN++V  +C LKI 
Sbjct: 111 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168

Query: 61  DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
           DFG+AR   TS     + MT YV TR+YRAPE++L +  Y + +D+WSVGCI GEM+  +
Sbjct: 169 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGEMVRHK 222

Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGA--- 177
            LFPG++Y+ Q   ++  LGTP P  ++ +    VR Y+++ P    + +  ++P +   
Sbjct: 223 ILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRNYVENRPKYAGLTFPKLFPDSLFP 281

Query: 178 ---------DRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226
                      QA  LL +ML  +P+ RIS   AL+HP++  ++DP  E +  PP  +D 
Sbjct: 282 ADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDP-AEVEAPPPQIYDK 340

Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265
             D    T E  KE I  E+ +   + + G+   ++ QPS
Sbjct: 341 QLDEREHTIEEWKELIYKEVMNSEEKTKNGV---VKGQPS 377


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,081,012
Number of Sequences: 37866
Number of extensions: 2972365
Number of successful extensions: 94079
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2147
Number of HSP's successfully gapped in prelim test: 2354
Number of HSP's that attempted gapping in prelim test: 20373
Number of HSP's gapped (non-prelim): 33314
length of query: 677
length of database: 18,247,518
effective HSP length: 109
effective length of query: 568
effective length of database: 14,120,124
effective search space: 8020230432
effective search space used: 8020230432
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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