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Search of human proteins with 20986499
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo
sapiens]
(677 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s... 1389 0.0
gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ... 1389 0.0
gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ... 1389 0.0
gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo s... 1389 0.0
gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo s... 268 1e-71
gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens] 262 7e-70
gi|66932916 mitogen-activated protein kinase 1 [Homo sapiens] 262 7e-70
gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo s... 246 5e-65
gi|20128774 mitogen-activated protein kinase 11 [Homo sapiens] 246 5e-65
gi|20986512 mitogen-activated protein kinase 14 isoform 2 [Homo ... 231 2e-60
gi|4503069 mitogen-activated protein kinase 14 isoform 1 [Homo s... 228 2e-59
gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens] 220 4e-57
gi|158138507 mitogen-activated protein kinase 3 isoform 3 [Homo ... 218 1e-56
gi|149408126 nemo like kinase [Homo sapiens] 206 4e-53
gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens] 201 2e-51
gi|48255970 mitogen-activated protein kinase 12 [Homo sapiens] 192 1e-48
gi|21237742 mitogen-activated protein kinase 9 isoform JNK2 beta... 188 2e-47
gi|21237745 mitogen-activated protein kinase 9 isoform JNK2 beta... 187 2e-47
gi|20986523 mitogen-activated protein kinase 8 isoform JNK1 alph... 182 7e-46
gi|4506095 mitogen-activated protein kinase 8 isoform JNK1 alpha... 182 7e-46
gi|20986514 mitogen-activated protein kinase 14 isoform 3 [Homo ... 182 7e-46
gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens] 181 2e-45
gi|21237739 mitogen-activated protein kinase 9 isoform JNK2 alph... 179 6e-45
gi|21237736 mitogen-activated protein kinase 9 isoform JNK2 alph... 179 7e-45
gi|20986521 mitogen-activated protein kinase 8 isoform JNK1 beta... 177 4e-44
gi|20986519 mitogen-activated protein kinase 8 isoform JNK1 beta... 177 4e-44
gi|4506081 mitogen-activated protein kinase 10 isoform 1 [Homo s... 176 5e-44
gi|20986510 mitogen-activated protein kinase 10 isoform 2 [Homo ... 176 5e-44
gi|20986508 mitogen-activated protein kinase 10 isoform 4 [Homo ... 176 5e-44
gi|20986506 mitogen-activated protein kinase 10 isoform 3 [Homo ... 176 5e-44
>gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 1389 bits (3596), Expect = 0.0
Identities = 677/677 (100%), Positives = 677/677 (100%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG
Sbjct: 140 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 199
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR
Sbjct: 200 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 259
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ
Sbjct: 260 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 319
Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE
Sbjct: 320 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 379
Query: 241 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 300
AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP
Sbjct: 380 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 439
Query: 301 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 360
PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL
Sbjct: 440 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 499
Query: 361 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 420
EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL
Sbjct: 500 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 559
Query: 421 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 480
VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ
Sbjct: 560 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 619
Query: 481 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 540
SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS
Sbjct: 620 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 679
Query: 541 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 600
TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA
Sbjct: 680 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 739
Query: 601 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 660
GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI
Sbjct: 740 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 799
Query: 661 QMDSPMLLADLPDLQDP 677
QMDSPMLLADLPDLQDP
Sbjct: 800 QMDSPMLLADLPDLQDP 816
>gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 1389 bits (3596), Expect = 0.0
Identities = 677/677 (100%), Positives = 677/677 (100%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG
Sbjct: 140 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 199
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR
Sbjct: 200 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 259
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ
Sbjct: 260 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 319
Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE
Sbjct: 320 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 379
Query: 241 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 300
AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP
Sbjct: 380 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 439
Query: 301 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 360
PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL
Sbjct: 440 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 499
Query: 361 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 420
EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL
Sbjct: 500 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 559
Query: 421 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 480
VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ
Sbjct: 560 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 619
Query: 481 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 540
SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS
Sbjct: 620 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 679
Query: 541 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 600
TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA
Sbjct: 680 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 739
Query: 601 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 660
GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI
Sbjct: 740 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 799
Query: 661 QMDSPMLLADLPDLQDP 677
QMDSPMLLADLPDLQDP
Sbjct: 800 QMDSPMLLADLPDLQDP 816
>gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 1389 bits (3596), Expect = 0.0
Identities = 677/677 (100%), Positives = 677/677 (100%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG
Sbjct: 140 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 199
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR
Sbjct: 200 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 259
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ
Sbjct: 260 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 319
Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE
Sbjct: 320 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 379
Query: 241 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 300
AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP
Sbjct: 380 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 439
Query: 301 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 360
PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL
Sbjct: 440 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 499
Query: 361 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 420
EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL
Sbjct: 500 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 559
Query: 421 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 480
VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ
Sbjct: 560 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 619
Query: 481 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 540
SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS
Sbjct: 620 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 679
Query: 541 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 600
TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA
Sbjct: 680 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 739
Query: 601 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 660
GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI
Sbjct: 740 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 799
Query: 661 QMDSPMLLADLPDLQDP 677
QMDSPMLLADLPDLQDP
Sbjct: 800 QMDSPMLLADLPDLQDP 816
>gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo
sapiens]
Length = 677
Score = 1389 bits (3596), Expect = 0.0
Identities = 677/677 (100%), Positives = 677/677 (100%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG
Sbjct: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR
Sbjct: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ
Sbjct: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE
Sbjct: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
Query: 241 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 300
AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP
Sbjct: 241 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPP 300
Query: 301 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 360
PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL
Sbjct: 301 PCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPL 360
Query: 361 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 420
EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL
Sbjct: 361 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDPLAGL 420
Query: 421 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 480
VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ
Sbjct: 421 VLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQ 480
Query: 481 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 540
SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS
Sbjct: 481 SAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSS 540
Query: 541 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 600
TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA
Sbjct: 541 TPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPPVFSGTPKGSGA 600
Query: 601 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 660
GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI
Sbjct: 601 GYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREI 660
Query: 661 QMDSPMLLADLPDLQDP 677
QMDSPMLLADLPDLQDP
Sbjct: 661 QMDSPMLLADLPDLQDP 677
>gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo
sapiens]
Length = 379
Score = 268 bits (685), Expect = 1e-71
Identities = 130/249 (52%), Positives = 177/249 (71%), Gaps = 2/249 (0%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
ME+DL++++ S Q L+ +H+ YFLYQ+LRGLKY+HSA V+HRDLKPSNLL+N C+LKI
Sbjct: 125 METDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKIC 183
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR + +H F+TEYVATRWYRAPE+ML+ YT++ID+WSVGCI EML+ R
Sbjct: 184 DFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 242
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
+FPGK+Y+ QL I+ +LG+PS + + + R Y+QSLP + V W ++P +D +
Sbjct: 243 PIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSK 302
Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
AL LL RML F P+ RI+ AL HP+L +Y+DP DEP PF FA + + L +ER+KE
Sbjct: 303 ALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKE 362
Query: 241 AIVAEIEDF 249
I E F
Sbjct: 363 LIFQETARF 371
>gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens]
Length = 360
Score = 262 bits (670), Expect = 7e-70
Identities = 127/249 (51%), Positives = 174/249 (69%), Gaps = 2/249 (0%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
ME+DL++++ +Q L+ +H+ YFLYQ+LRGLKY+HSA V+HRDLKPSNLL+N C+LKI
Sbjct: 108 METDLYKLL-KTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKIC 166
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR + +H F+TEYVATRWYRAPE+ML+ YT++ID+WSVGCI EML+ R
Sbjct: 167 DFGLAR-VADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 225
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
+FPGK+Y+ QL I+ +LG+PS + + + R Y+ SLP + VPW ++P AD +
Sbjct: 226 PIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSK 285
Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
AL LL +ML F P RI AL HP+L +Y+DP DEP PF F + + L +E++KE
Sbjct: 286 ALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKE 345
Query: 241 AIVAEIEDF 249
I E F
Sbjct: 346 LIFEETARF 354
>gi|66932916 mitogen-activated protein kinase 1 [Homo sapiens]
Length = 360
Score = 262 bits (670), Expect = 7e-70
Identities = 127/249 (51%), Positives = 174/249 (69%), Gaps = 2/249 (0%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
ME+DL++++ +Q L+ +H+ YFLYQ+LRGLKY+HSA V+HRDLKPSNLL+N C+LKI
Sbjct: 108 METDLYKLL-KTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKIC 166
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR + +H F+TEYVATRWYRAPE+ML+ YT++ID+WSVGCI EML+ R
Sbjct: 167 DFGLAR-VADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 225
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
+FPGK+Y+ QL I+ +LG+PS + + + R Y+ SLP + VPW ++P AD +
Sbjct: 226 PIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSK 285
Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
AL LL +ML F P RI AL HP+L +Y+DP DEP PF F + + L +E++KE
Sbjct: 286 ALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKE 345
Query: 241 AIVAEIEDF 249
I E F
Sbjct: 346 LIFEETARF 354
>gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo
sapiens]
Length = 357
Score = 246 bits (628), Expect = 5e-65
Identities = 118/222 (53%), Positives = 162/222 (72%), Gaps = 2/222 (0%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
ME+DL++++ S Q L+ +H+ YFLYQ+LRGLKY+HSA V+HRDLKPSNLL+N C+LKI
Sbjct: 125 METDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKIC 183
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR + +H F+TEYVATRWYRAPE+ML+ YT++ID+WSVGCI EML+ R
Sbjct: 184 DFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 242
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
+FPGK+Y+ QL I+ +LG+PS + + + R Y+QSLP + V W ++P +D +
Sbjct: 243 PIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSK 302
Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAP 222
AL LL RML F P+ RI+ AL HP+L +Y+DP DE +P
Sbjct: 303 ALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEVGQSP 344
>gi|20128774 mitogen-activated protein kinase 11 [Homo sapiens]
Length = 364
Score = 246 bits (628), Expect = 5e-65
Identities = 126/249 (50%), Positives = 171/249 (68%), Gaps = 9/249 (3%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M +DL+ I+ Q L+ EHV++ +YQLLRGLKY+HSA +IHRDLKPSN+ VNE+CEL+I
Sbjct: 109 MGADLNNIV-KCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRIL 167
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR A+ + MT YVATRWYRAPE+ML+ Y Q +D+WSVGCI E+L +
Sbjct: 168 DFGLAR-----QADEE--MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGK 220
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
LFPG +Y+ QL+ IM V+GTPSP V+ + +E R YIQSLPP +++ GA+
Sbjct: 221 ALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPL 280
Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
A+ LLGRML + R+SAA AL H + ++YHDP+DEP+ A P+D + + + T E KE
Sbjct: 281 AIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPE-AEPYDESVEAKERTLEEWKE 339
Query: 241 AIVAEIEDF 249
E+ F
Sbjct: 340 LTYQEVLSF 348
>gi|20986512 mitogen-activated protein kinase 14 isoform 2 [Homo
sapiens]
Length = 360
Score = 231 bits (588), Expect = 2e-60
Identities = 120/249 (48%), Positives = 164/249 (65%), Gaps = 9/249 (3%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M +DL+ I+ Q LT +HV++ +YQ+LRGLKY+HSA +IHRDLKPSNL VNE+CELKI
Sbjct: 109 MGADLNNIV-KCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKIL 167
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR MT YVATRWYRAPE+ML+ Y Q +D+WSVGCI E+L R
Sbjct: 168 DFGLARHTDDE-------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGR 220
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
LFPG +++ QL+LI+ ++GTP +++ + +E R YIQSL + + V+ GA+
Sbjct: 221 TLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPL 280
Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
A+ LL +ML + RI+AA AL H + A+YHDPDDEP A P+D +F+ L + K
Sbjct: 281 AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEP-VADPYDQSFESRDLLIDEWKS 339
Query: 241 AIVAEIEDF 249
E+ F
Sbjct: 340 LTYDEVISF 348
>gi|4503069 mitogen-activated protein kinase 14 isoform 1 [Homo
sapiens]
Length = 360
Score = 228 bits (580), Expect = 2e-59
Identities = 121/249 (48%), Positives = 161/249 (64%), Gaps = 9/249 (3%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M +DL+ I+ Q LT +HV++ +YQ+LRGLKY+HSA +IHRDLKPSNL VNE+CELKI
Sbjct: 109 MGADLNNIV-KCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKIL 167
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR MT YVATRWYRAPE+ML+ Y Q +D+WSVGCI E+L R
Sbjct: 168 DFGLARHTDDE-------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGR 220
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
LFPG ++++QLQ IM + GTP +I + + R YIQSL + + V+ GA+
Sbjct: 221 TLFPGTDHINQLQQIMRLTGTPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPL 280
Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
A+ LL +ML + RI+AA AL H + A+YHDPDDEP A P+D +F+ L + K
Sbjct: 281 AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEP-VADPYDQSFESRDLLIDEWKS 339
Query: 241 AIVAEIEDF 249
E+ F
Sbjct: 340 LTYDEVISF 348
>gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens]
Length = 365
Score = 220 bits (560), Expect = 4e-57
Identities = 117/260 (45%), Positives = 164/260 (63%), Gaps = 11/260 (4%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M++DL +I+ + E ++Y +YQ+L+GLKY+HSA V+HRDLKP NL VNE+CELKI
Sbjct: 110 MQTDLQKIM--GMEFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKIL 167
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR + AE MT YV TRWYRAPE++LS Y Q +D+WSVGCI EML +
Sbjct: 168 DFGLARH---ADAE----MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGK 220
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
LF GK+Y+ QL I+ V G P +Q + + ++YIQSLP + ++P A Q
Sbjct: 221 TLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQSLPQTPRKDFTQLFPRASPQ 280
Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
A LL +ML + R++AA AL HPF + DP++E + PFD + + E LT + K+
Sbjct: 281 AADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQQPFDDSLEHEKLTVDEWKQ 340
Query: 241 AIVAEIEDFH--ARREGIRQ 258
I EI +F AR++ R+
Sbjct: 341 HIYKEIVNFSPIARKDSRRR 360
>gi|158138507 mitogen-activated protein kinase 3 isoform 3 [Homo
sapiens]
Length = 335
Score = 218 bits (555), Expect = 1e-56
Identities = 116/249 (46%), Positives = 152/249 (61%), Gaps = 46/249 (18%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
ME+DL++++ S Q L+ +H+ YFLYQ+LRGLKY+HSA V+HRDLKPSNLL+N C+LKI
Sbjct: 125 METDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKIC 183
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR + +H F+TEYVATRWYRAPE+ML+ YT++ID+WSVGCI EML+ R
Sbjct: 184 DFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 242
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
+FPGK+Y+ QL I+
Sbjct: 243 PIFPGKHYLDQLNHIL-------------------------------------------- 258
Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
AL LL RML F P+ RI+ AL HP+L +Y+DP DEP PF FA + + L +ER+KE
Sbjct: 259 ALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKE 318
Query: 241 AIVAEIEDF 249
I E F
Sbjct: 319 LIFQETARF 327
>gi|149408126 nemo like kinase [Homo sapiens]
Length = 527
Score = 206 bits (525), Expect = 4e-53
Identities = 120/264 (45%), Positives = 162/264 (61%), Gaps = 26/264 (9%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M+SDLH+II S QPL+ +HV+ FLYQ+LRGLKY+HSA ++HRD+KP NLLVN NC LKI
Sbjct: 222 MQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKIC 281
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR + MT+ V T++YRAPE+++ Y+ AID+WSVGCIF E+L RR
Sbjct: 282 DFGLAR---VEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRR 338
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQP-VP-WETVYPGAD 178
LF ++ + QL LI +LGTPS ++ E +A+I P +QP +P T+ A
Sbjct: 339 ILFQAQSPIQQLDLITDLLGTPSLEAMR-TACEGAKAHILRGPHKQPSLPVLYTLSSQAT 397
Query: 179 RQALSLLGRMLRFEPSARISAAAALRHPFL----AKYH----------------DPDDEP 218
+A+ LL RML F+PS RISA AL HP+L +YH D EP
Sbjct: 398 HEAVHLLCRMLVFDPSKRISAKDALAHPYLDEGRLRYHTCMCKCCFSTSTGRVYTSDFEP 457
Query: 219 DCAPPFDFAFDREALTRERIKEAI 242
P FD F++ + ++KE I
Sbjct: 458 VTNPKFDDTFEKNLSSVRQVKEII 481
>gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens]
Length = 544
Score = 201 bits (510), Expect = 2e-51
Identities = 130/354 (36%), Positives = 183/354 (51%), Gaps = 33/354 (9%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M++DL+ +I L HVR YQLLR +++HS V+HRD KPSN+L++ NC +K+
Sbjct: 95 MDTDLNAVIRKGGLLQDVHVRSIFYQLLRATRFLHSGHVVHRDQKPSNVLLDANCTVKLC 154
Query: 61 DFGMARGLCTSP-AEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR 119
DFG+AR L P +TEYVATRWYRAPE++LS H YT +D+WS+GCI GEML
Sbjct: 155 DFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEVLLSSHRYTLGVDMWSLGCILGEMLRG 214
Query: 120 RQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSL--PPRQPVPWETVYPGA 177
R LFPG + +HQL+LI+ + PS + A+G+ + + L PRQ + + P
Sbjct: 215 RPLFPGTSTLHQLELILETIPPPSEEDLLALGSGCRASVLHQLGSRPRQTLD-ALLPPDT 273
Query: 178 DRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRER 237
+AL LL R+L F P R+SA AL+HP++ ++H P DE + REA R R
Sbjct: 274 SPEALDLLRRLLVFAPDKRLSATQALQHPYVQRFHCPSDE----------WAREADVRPR 323
Query: 238 IKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSP---WAPSGDCAMES 294
E + + ++ +R + Q I + E G P+ PS P D + S
Sbjct: 324 AHEGVQLSVPEYRSR---VYQMILECGGSSGTSREKG-PEGVSPSQAHLHKPRADPQLPS 379
Query: 295 PPPAPPPCPGPAPDTIDLTLQPPP---PVSEPAPPKKDGAISDNTKAALKAALL 345
P P P P Q P P +P N+ L+ ALL
Sbjct: 380 RTPVQGPRPRP---------QSSPGHDPAEHESPRAAKNVPRQNSAPLLQTALL 424
>gi|48255970 mitogen-activated protein kinase 12 [Homo sapiens]
Length = 367
Score = 192 bits (487), Expect = 1e-48
Identities = 99/254 (38%), Positives = 153/254 (60%), Gaps = 9/254 (3%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M +DL +++ + L + +++ +YQ+L+GL+Y+H+A +IHRDLKP NL VNE+CELKI
Sbjct: 112 MGTDLGKLM-KHEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKIL 170
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR + MT YV TRWYRAPE++L+ YTQ +D+WSVGCI EM+ +
Sbjct: 171 DFGLARQADSE-------MTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGK 223
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
LF G +++ QL+ IM V GTP +Q + ++ + Y++ LP + + ++ A
Sbjct: 224 TLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASILTNASPL 283
Query: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
A++LL +ML + R++A AL HP+ HD +DEP +D +FD T + K
Sbjct: 284 AVNLLEKMLVLDAEQRVTAGEALAHPYFESLHDTEDEPQ-VQKYDDSFDDVDRTLDEWKR 342
Query: 241 AIVAEIEDFHARRE 254
E+ F R+
Sbjct: 343 VTYKEVLSFKPPRQ 356
>gi|21237742 mitogen-activated protein kinase 9 isoform JNK2 beta1
[Homo sapiens]
Length = 382
Score = 188 bits (477), Expect = 2e-47
Identities = 110/282 (39%), Positives = 165/282 (58%), Gaps = 28/282 (9%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M+++L Q+IH L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI
Sbjct: 111 MDANLCQVIHME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR CT+ + MT YV TR+YRAPE++L + Y + +D+WSVGCI EM+ +
Sbjct: 169 DFGLARTACTN-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMAEMVLHK 222
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176
LFPG++Y+ Q ++ LGTPS ++ + VR Y+++ P + +E ++P
Sbjct: 223 VLFPGRDYIDQWNKVIEQLGTPSAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFP 281
Query: 177 --------ADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226
QA LL +ML +P RIS ALRHP++ ++DP E + PP +D
Sbjct: 282 SESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDP-AEAEAPPPQIYDA 340
Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPSLQ 267
+ E KE I E+ D+ R + G+ ++ QPS Q
Sbjct: 341 QLEEREHAIEEWKELIYKEVMDWEERSKNGV---VKDQPSAQ 379
>gi|21237745 mitogen-activated protein kinase 9 isoform JNK2 beta2
[Homo sapiens]
Length = 424
Score = 187 bits (476), Expect = 2e-47
Identities = 111/286 (38%), Positives = 167/286 (58%), Gaps = 28/286 (9%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M+++L Q+IH L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI
Sbjct: 111 MDANLCQVIHME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR CT+ + MT YV TR+YRAPE++L + Y + +D+WSVGCI EM+ +
Sbjct: 169 DFGLARTACTN-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMAEMVLHK 222
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176
LFPG++Y+ Q ++ LGTPS ++ + VR Y+++ P + +E ++P
Sbjct: 223 VLFPGRDYIDQWNKVIEQLGTPSAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFP 281
Query: 177 --------ADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226
QA LL +ML +P RIS ALRHP++ ++DP E + PP +D
Sbjct: 282 SESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDP-AEAEAPPPQIYDA 340
Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPSLQPVAS 271
+ E KE I E+ D+ R + G+ ++ QPS V+S
Sbjct: 341 QLEEREHAIEEWKELIYKEVMDWEERSKNGV---VKDQPSDAAVSS 383
>gi|20986523 mitogen-activated protein kinase 8 isoform JNK1 alpha2
[Homo sapiens]
Length = 427
Score = 182 bits (463), Expect = 7e-46
Identities = 115/280 (41%), Positives = 163/280 (58%), Gaps = 28/280 (10%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M+++L Q+I L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI
Sbjct: 111 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR TS + MT YV TR+YRAPE++L + Y + +DLWSVGCI GEM+ +
Sbjct: 169 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDLWSVGCIMGEMVCHK 222
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176
LFPG++Y+ Q ++ LGTP P ++ + VR Y+++ P +E ++P
Sbjct: 223 ILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFP 281
Query: 177 AD--------RQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPF--DF 226
AD QA LL +ML + S RIS AL+HP++ ++DP E + PP D
Sbjct: 282 ADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDP-SEAEAPPPKIPDK 340
Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265
D T E KE I E+ D R + G+ IR QPS
Sbjct: 341 QLDEREHTIEEWKELIYKEVMDLEERTKNGV---IRGQPS 377
>gi|4506095 mitogen-activated protein kinase 8 isoform JNK1 alpha1
[Homo sapiens]
Length = 384
Score = 182 bits (463), Expect = 7e-46
Identities = 115/280 (41%), Positives = 163/280 (58%), Gaps = 28/280 (10%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M+++L Q+I L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI
Sbjct: 111 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR TS + MT YV TR+YRAPE++L + Y + +DLWSVGCI GEM+ +
Sbjct: 169 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDLWSVGCIMGEMVCHK 222
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176
LFPG++Y+ Q ++ LGTP P ++ + VR Y+++ P +E ++P
Sbjct: 223 ILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFP 281
Query: 177 AD--------RQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPF--DF 226
AD QA LL +ML + S RIS AL+HP++ ++DP E + PP D
Sbjct: 282 ADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDP-SEAEAPPPKIPDK 340
Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265
D T E KE I E+ D R + G+ IR QPS
Sbjct: 341 QLDEREHTIEEWKELIYKEVMDLEERTKNGV---IRGQPS 377
>gi|20986514 mitogen-activated protein kinase 14 isoform 3 [Homo
sapiens]
Length = 297
Score = 182 bits (463), Expect = 7e-46
Identities = 91/178 (51%), Positives = 124/178 (69%), Gaps = 8/178 (4%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M +DL+ I+ Q LT +HV++ +YQ+LRGLKY+HSA +IHRDLKPSNL VNE+CELKI
Sbjct: 109 MGADLNNIV-KCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKIL 167
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR MT YVATRWYRAPE+ML+ Y Q +D+WSVGCI E+L R
Sbjct: 168 DFGLARHTDDE-------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGR 220
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGAD 178
LFPG +++ QL+LI+ ++GTP +++ + +E R YIQSL + + V+ GA+
Sbjct: 221 TLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGAN 278
>gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens]
Length = 721
Score = 181 bits (459), Expect = 2e-45
Identities = 100/228 (43%), Positives = 142/228 (62%), Gaps = 10/228 (4%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVN-ENCELKI 59
ME+DL ++ PL EH R F+YQLLRGLKY+HSA V+HRDLKP+NL +N E+ LKI
Sbjct: 111 METDLANVLEQG-PLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKI 169
Query: 60 GDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR 119
GDFG+AR + H+ ++E + T+WYR+P L+LS + YT+AID+W+ GCIF EML
Sbjct: 170 GDFGLAR-IMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTG 228
Query: 120 RQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAER---VRAYIQSLPPRQPVPWETVYPG 176
+ LF G + + Q+QLI+ + P V + E + YI++ P + PG
Sbjct: 229 KTLFAGAHELEQMQLILESI----PVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPG 284
Query: 177 ADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPF 224
R+AL L ++L F P R++A AL HP+++ Y P DEP + PF
Sbjct: 285 ISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPMDEPISSHPF 332
>gi|21237739 mitogen-activated protein kinase 9 isoform JNK2 alpha1
[Homo sapiens]
Length = 382
Score = 179 bits (455), Expect = 6e-45
Identities = 107/282 (37%), Positives = 163/282 (57%), Gaps = 28/282 (9%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M+++L Q+IH L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI
Sbjct: 111 MDANLCQVIHME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR CT+ + MT YV TR+YRAPE++L + Y + +D+WSVGCI GE++
Sbjct: 169 DFGLARTACTN-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGELVKGC 222
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176
+F G +++ Q ++ LGTPS ++ + VR Y+++ P + +E ++P
Sbjct: 223 VIFQGTDHIDQWNKVIEQLGTPSAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFP 281
Query: 177 --------ADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226
QA LL +ML +P RIS ALRHP++ ++DP E + PP +D
Sbjct: 282 SESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDP-AEAEAPPPQIYDA 340
Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPSLQ 267
+ E KE I E+ D+ R + G+ ++ QPS Q
Sbjct: 341 QLEEREHAIEEWKELIYKEVMDWEERSKNGV---VKDQPSAQ 379
>gi|21237736 mitogen-activated protein kinase 9 isoform JNK2 alpha2
[Homo sapiens]
Length = 424
Score = 179 bits (454), Expect = 7e-45
Identities = 108/286 (37%), Positives = 165/286 (57%), Gaps = 28/286 (9%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M+++L Q+IH L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI
Sbjct: 111 MDANLCQVIHME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR CT+ + MT YV TR+YRAPE++L + Y + +D+WSVGCI GE++
Sbjct: 169 DFGLARTACTN-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGELVKGC 222
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176
+F G +++ Q ++ LGTPS ++ + VR Y+++ P + +E ++P
Sbjct: 223 VIFQGTDHIDQWNKVIEQLGTPSAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFP 281
Query: 177 --------ADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226
QA LL +ML +P RIS ALRHP++ ++DP E + PP +D
Sbjct: 282 SESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDP-AEAEAPPPQIYDA 340
Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPSLQPVAS 271
+ E KE I E+ D+ R + G+ ++ QPS V+S
Sbjct: 341 QLEEREHAIEEWKELIYKEVMDWEERSKNGV---VKDQPSDAAVSS 383
>gi|20986521 mitogen-activated protein kinase 8 isoform JNK1 beta2
[Homo sapiens]
Length = 427
Score = 177 bits (448), Expect = 4e-44
Identities = 113/280 (40%), Positives = 161/280 (57%), Gaps = 28/280 (10%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M+++L Q+I L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI
Sbjct: 111 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR TS + MT YV TR+YRAPE++L + Y + +D+WSVGCI GEM+
Sbjct: 169 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGEMIKGG 222
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176
LFPG +++ Q ++ LGTP P ++ + VR Y+++ P +E ++P
Sbjct: 223 VLFPGTDHIDQWNKVIEQLGTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFP 281
Query: 177 AD--------RQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPF--DF 226
AD QA LL +ML + S RIS AL+HP++ ++DP E + PP D
Sbjct: 282 ADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDP-SEAEAPPPKIPDK 340
Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265
D T E KE I E+ D R + G+ IR QPS
Sbjct: 341 QLDEREHTIEEWKELIYKEVMDLEERTKNGV---IRGQPS 377
>gi|20986519 mitogen-activated protein kinase 8 isoform JNK1 beta1
[Homo sapiens]
Length = 384
Score = 177 bits (448), Expect = 4e-44
Identities = 113/280 (40%), Positives = 161/280 (57%), Gaps = 28/280 (10%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M+++L Q+I L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI
Sbjct: 111 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR TS + MT YV TR+YRAPE++L + Y + +D+WSVGCI GEM+
Sbjct: 169 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGEMIKGG 222
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPG---- 176
LFPG +++ Q ++ LGTP P ++ + VR Y+++ P +E ++P
Sbjct: 223 VLFPGTDHIDQWNKVIEQLGTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFP 281
Query: 177 AD--------RQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPF--DF 226
AD QA LL +ML + S RIS AL+HP++ ++DP E + PP D
Sbjct: 282 ADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDP-SEAEAPPPKIPDK 340
Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265
D T E KE I E+ D R + G+ IR QPS
Sbjct: 341 QLDEREHTIEEWKELIYKEVMDLEERTKNGV---IRGQPS 377
>gi|4506081 mitogen-activated protein kinase 10 isoform 1 [Homo
sapiens]
Length = 422
Score = 176 bits (447), Expect = 5e-44
Identities = 107/280 (38%), Positives = 164/280 (58%), Gaps = 28/280 (10%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M+++L Q+I L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI
Sbjct: 149 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 206
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR TS + MT YV TR+YRAPE++L + Y + +D+WSVGCI GEM+ +
Sbjct: 207 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGEMVRHK 260
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGA--- 177
LFPG++Y+ Q ++ LGTP P ++ + VR Y+++ P + + ++P +
Sbjct: 261 ILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRNYVENRPKYAGLTFPKLFPDSLFP 319
Query: 178 ---------DRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226
QA LL +ML +P+ RIS AL+HP++ ++DP E + PP +D
Sbjct: 320 ADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDP-AEVEAPPPQIYDK 378
Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265
D T E KE I E+ + + + G+ ++ QPS
Sbjct: 379 QLDEREHTIEEWKELIYKEVMNSEEKTKNGV---VKGQPS 415
>gi|20986510 mitogen-activated protein kinase 10 isoform 2 [Homo
sapiens]
Length = 464
Score = 176 bits (447), Expect = 5e-44
Identities = 107/280 (38%), Positives = 164/280 (58%), Gaps = 28/280 (10%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M+++L Q+I L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI
Sbjct: 149 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 206
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR TS + MT YV TR+YRAPE++L + Y + +D+WSVGCI GEM+ +
Sbjct: 207 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGEMVRHK 260
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGA--- 177
LFPG++Y+ Q ++ LGTP P ++ + VR Y+++ P + + ++P +
Sbjct: 261 ILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRNYVENRPKYAGLTFPKLFPDSLFP 319
Query: 178 ---------DRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226
QA LL +ML +P+ RIS AL+HP++ ++DP E + PP +D
Sbjct: 320 ADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDP-AEVEAPPPQIYDK 378
Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265
D T E KE I E+ + + + G+ ++ QPS
Sbjct: 379 QLDEREHTIEEWKELIYKEVMNSEEKTKNGV---VKGQPS 415
>gi|20986508 mitogen-activated protein kinase 10 isoform 4 [Homo
sapiens]
Length = 277
Score = 176 bits (447), Expect = 5e-44
Identities = 107/280 (38%), Positives = 164/280 (58%), Gaps = 28/280 (10%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M+++L Q+I L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI
Sbjct: 4 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 61
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR TS + MT YV TR+YRAPE++L + Y + +D+WSVGCI GEM+ +
Sbjct: 62 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGEMVRHK 115
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGA--- 177
LFPG++Y+ Q ++ LGTP P ++ + VR Y+++ P + + ++P +
Sbjct: 116 ILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRNYVENRPKYAGLTFPKLFPDSLFP 174
Query: 178 ---------DRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226
QA LL +ML +P+ RIS AL+HP++ ++DP E + PP +D
Sbjct: 175 ADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDP-AEVEAPPPQIYDK 233
Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265
D T E KE I E+ + + + G+ ++ QPS
Sbjct: 234 QLDEREHTIEEWKELIYKEVMNSEEKTKNGV---VKGQPS 270
>gi|20986506 mitogen-activated protein kinase 10 isoform 3 [Homo
sapiens]
Length = 426
Score = 176 bits (447), Expect = 5e-44
Identities = 107/280 (38%), Positives = 164/280 (58%), Gaps = 28/280 (10%)
Query: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
M+++L Q+I L E + Y LYQ+L G+K++HSA +IHRDLKPSN++V +C LKI
Sbjct: 111 MDANLCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL 168
Query: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
DFG+AR TS + MT YV TR+YRAPE++L + Y + +D+WSVGCI GEM+ +
Sbjct: 169 DFGLARTAGTS-----FMMTPYVVTRYYRAPEVILGM-GYKENVDIWSVGCIMGEMVRHK 222
Query: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGA--- 177
LFPG++Y+ Q ++ LGTP P ++ + VR Y+++ P + + ++P +
Sbjct: 223 ILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRNYVENRPKYAGLTFPKLFPDSLFP 281
Query: 178 ---------DRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP--FDF 226
QA LL +ML +P+ RIS AL+HP++ ++DP E + PP +D
Sbjct: 282 ADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDP-AEVEAPPPQIYDK 340
Query: 227 AFDREALTRERIKEAIVAEIEDFHAR-REGIRQQIRFQPS 265
D T E KE I E+ + + + G+ ++ QPS
Sbjct: 341 QLDEREHTIEEWKELIYKEVMNSEEKTKNGV---VKGQPS 377
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,081,012
Number of Sequences: 37866
Number of extensions: 2972365
Number of successful extensions: 94079
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2147
Number of HSP's successfully gapped in prelim test: 2354
Number of HSP's that attempted gapping in prelim test: 20373
Number of HSP's gapped (non-prelim): 33314
length of query: 677
length of database: 18,247,518
effective HSP length: 109
effective length of query: 568
effective length of database: 14,120,124
effective search space: 8020230432
effective search space used: 8020230432
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.