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Search of human proteins with 209862907
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|209862907 periostin, osteoblast specific factor isoform 1
[Homo sapiens]
(836 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209862907 periostin, osteoblast specific factor isoform 1 [Ho... 1652 0.0
gi|209863011 periostin, osteoblast specific factor isoform 3 [Ho... 1515 0.0
gi|209862911 periostin, osteoblast specific factor isoform 2 [Ho... 1454 0.0
gi|209863034 periostin, osteoblast specific factor isoform 4 [Ho... 1424 0.0
gi|4507467 transforming growth factor, beta-induced, 68kDa precu... 597 e-170
gi|61743980 stabilin 2 precursor [Homo sapiens] 74 6e-13
gi|61743978 stabilin 1 precursor [Homo sapiens] 59 1e-08
gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens] 34 0.64
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens] 34 0.64
gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens] 34 0.64
gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens] 34 0.64
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 33 1.1
gi|50843820 sickle tail isoform 1 [Homo sapiens] 32 1.9
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 32 1.9
gi|93102367 ral guanine nucleotide dissociation stimulator-like ... 32 2.4
gi|131889097 cancer susceptibility candidate 1 isoform b [Homo s... 32 2.4
gi|131889447 cancer susceptibility candidate 1 isoform c [Homo s... 32 2.4
gi|131888105 cancer susceptibility candidate 1 isoform a [Homo s... 32 2.4
gi|118498362 kinectin 1 isoform b [Homo sapiens] 31 4.2
gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens] 31 5.4
gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] 31 5.4
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 31 5.4
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 31 5.4
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 31 5.4
gi|32130514 N-myc downstream-regulated gene 3 isoform b [Homo sa... 30 7.1
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ... 30 7.1
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ... 30 7.1
gi|38569428 ankyrin repeat domain protein 5 [Homo sapiens] 30 7.1
gi|38569426 ankyrin repeat domain protein 5 [Homo sapiens] 30 7.1
gi|108773797 ganglioside-induced differentiation-associated prot... 30 9.3
>gi|209862907 periostin, osteoblast specific factor isoform 1 [Homo
sapiens]
Length = 836
Score = 1652 bits (4279), Expect = 0.0
Identities = 836/836 (100%), Positives = 836/836 (100%)
Query: 1 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC 60
MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
Sbjct: 1 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC 60
Query: 61 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS 120
KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
Sbjct: 61 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS 120
Query: 121 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK 180
KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
Sbjct: 121 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK 180
Query: 181 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF 240
NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
Sbjct: 181 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF 240
Query: 241 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL 300
IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
Sbjct: 241 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL 300
Query: 301 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL 360
MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
Sbjct: 301 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL 360
Query: 361 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM 420
IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
Sbjct: 361 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM 420
Query: 421 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG 480
DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
Sbjct: 421 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG 480
Query: 481 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA 540
RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
Sbjct: 481 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA 540
Query: 541 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND 600
FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
Sbjct: 541 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND 600
Query: 601 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST 660
TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
Sbjct: 601 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST 660
Query: 661 FKEIPVTVYTTKIITKVVEPKIKVIEGSLQPIIKTEGPTLTKVKIEGEPEFRLIKEGETI 720
FKEIPVTVYTTKIITKVVEPKIKVIEGSLQPIIKTEGPTLTKVKIEGEPEFRLIKEGETI
Sbjct: 661 FKEIPVTVYTTKIITKVVEPKIKVIEGSLQPIIKTEGPTLTKVKIEGEPEFRLIKEGETI 720
Query: 721 TEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLL 780
TEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLL
Sbjct: 721 TEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLL 780
Query: 781 QEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ 836
QEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ
Sbjct: 781 QEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ 836
>gi|209863011 periostin, osteoblast specific factor isoform 3 [Homo
sapiens]
Length = 781
Score = 1515 bits (3922), Expect = 0.0
Identities = 780/836 (93%), Positives = 780/836 (93%), Gaps = 55/836 (6%)
Query: 1 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC 60
MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
Sbjct: 1 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC 60
Query: 61 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS 120
KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
Sbjct: 61 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS 120
Query: 121 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK 180
KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
Sbjct: 121 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK 180
Query: 181 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF 240
NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
Sbjct: 181 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF 240
Query: 241 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL 300
IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
Sbjct: 241 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL 300
Query: 301 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL 360
MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
Sbjct: 301 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL 360
Query: 361 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM 420
IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
Sbjct: 361 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM 420
Query: 421 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG 480
DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
Sbjct: 421 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG 480
Query: 481 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA 540
RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
Sbjct: 481 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA 540
Query: 541 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND 600
FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
Sbjct: 541 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND 600
Query: 601 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST 660
TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
Sbjct: 601 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST 660
Query: 661 FKEIPVTVYTTKIITKVVEPKIKVIEGSLQPIIKTEGPTLTKVKIEGEPEFRLIKEGETI 720
FKEIPVTVY PTLTKVKIEGEPEFRLIKEGETI
Sbjct: 661 FKEIPVTVYR---------------------------PTLTKVKIEGEPEFRLIKEGETI 693
Query: 721 TEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLL 780
TEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLL
Sbjct: 694 TEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLL 753
Query: 781 QEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ 836
QE DTPVRKLQANKKVQGSRRRLREGRSQ
Sbjct: 754 QE----------------------------DTPVRKLQANKKVQGSRRRLREGRSQ 781
>gi|209862911 periostin, osteoblast specific factor isoform 2 [Homo
sapiens]
Length = 779
Score = 1454 bits (3764), Expect = 0.0
Identities = 758/836 (90%), Positives = 762/836 (91%), Gaps = 57/836 (6%)
Query: 1 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC 60
MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
Sbjct: 1 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC 60
Query: 61 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS 120
KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
Sbjct: 61 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS 120
Query: 121 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK 180
KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
Sbjct: 121 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK 180
Query: 181 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF 240
NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
Sbjct: 181 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF 240
Query: 241 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL 300
IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
Sbjct: 241 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL 300
Query: 301 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL 360
MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
Sbjct: 301 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL 360
Query: 361 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM 420
IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
Sbjct: 361 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM 420
Query: 421 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG 480
DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
Sbjct: 421 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG 480
Query: 481 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA 540
RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
Sbjct: 481 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA 540
Query: 541 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND 600
FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
Sbjct: 541 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND 600
Query: 601 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST 660
TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
Sbjct: 601 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST 660
Query: 661 FKEIPVTVYTTKIITKVVEPKIKVIEGSLQPIIKTEGPTLTKVKIEGEPEFRLIKEGETI 720
FKEIPVTVY +PIIK + V +E I E ET
Sbjct: 661 FKEIPVTVY--------------------KPIIKKYTKIIDGVPVE-------ITEKETR 693
Query: 721 TEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLL 780
E I P I KYT+I STGGGETEETLKKLL
Sbjct: 694 EERIITGPEI-KYTRI-----------------------------STGGGETEETLKKLL 723
Query: 781 QEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ 836
QEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ
Sbjct: 724 QEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ 779
>gi|209863034 periostin, osteoblast specific factor isoform 4 [Homo
sapiens]
Length = 751
Score = 1424 bits (3687), Expect = 0.0
Identities = 744/836 (88%), Positives = 747/836 (89%), Gaps = 85/836 (10%)
Query: 1 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC 60
MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
Sbjct: 1 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC 60
Query: 61 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS 120
KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
Sbjct: 61 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS 120
Query: 121 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK 180
KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
Sbjct: 121 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK 180
Query: 181 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF 240
NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
Sbjct: 181 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF 240
Query: 241 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL 300
IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
Sbjct: 241 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL 300
Query: 301 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL 360
MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
Sbjct: 301 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL 360
Query: 361 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM 420
IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
Sbjct: 361 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM 420
Query: 421 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG 480
DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
Sbjct: 421 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG 480
Query: 481 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA 540
RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
Sbjct: 481 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA 540
Query: 541 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND 600
FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
Sbjct: 541 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND 600
Query: 601 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST 660
TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
Sbjct: 601 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST 660
Query: 661 FKEIPVTVYTTKIITKVVEPKIKVIEGSLQPIIKTEGPTLTKVKIEGEPEFRLIKEGETI 720
FKEIPVTVY +PIIK
Sbjct: 661 FKEIPVTVY--------------------KPIIK------------------------KY 676
Query: 721 TEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLL 780
T++I G P VEITEKETREERIITGPEIKYTRISTGGGETEETLKKLL
Sbjct: 677 TKIIDGVP-------------VEITEKETREERIITGPEIKYTRISTGGGETEETLKKLL 723
Query: 781 QEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ 836
QE DTPVRKLQANKKVQGSRRRLREGRSQ
Sbjct: 724 QE----------------------------DTPVRKLQANKKVQGSRRRLREGRSQ 751
>gi|4507467 transforming growth factor, beta-induced, 68kDa
precursor [Homo sapiens]
Length = 683
Score = 597 bits (1539), Expect = e-170
Identities = 300/637 (47%), Positives = 420/637 (65%), Gaps = 10/637 (1%)
Query: 1 MIPFLPMFSLLLLLIVNPIN-----ANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKK 55
M F+ + +L L L + P A + Y +L HSR+RGR GPNVCA+Q+++GT +K
Sbjct: 1 MALFVRLLALALALALGPAATLAGPAKSPYQLVLQHSRLRGRQHGPNVCAVQKVIGTNRK 60
Query: 56 YFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQR 115
YF+ CK WY++ ICG+ T + YECCPGY ++ G KGCPA LP+ ++Y TLG+VG+TTTQ
Sbjct: 61 YFTNCKQWYQRKICGKSTVISYECCPGYEKVPGEKGCPAALPLSNLYETLGVVGSTTTQL 120
Query: 116 YSDAS-KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRM 174
Y+D + KLR E+EG GSFT FAPSNEAW +L +++ L SNVN+ELLNAL HM+ +R+
Sbjct: 121 YTDRTEKLRPEMEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVGRRV 180
Query: 175 LTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIG 234
LT +LK+GM + SMY N + I+HYPNG+VTVNCAR++ + ATNGVVH+ID+V++ I
Sbjct: 181 LTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTIT 240
Query: 235 TSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDK 294
+IQ IE ED + RAA S + L +G +TL APTNEAFEK+P L RI+GD
Sbjct: 241 NNIQQIIEIEDTFETLRAAVAASGLNTMLEGNGQYTLLAPTNEAFEKIPSETLNRILGDP 300
Query: 295 VASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTN 354
A L+ HIL + C+E+I+ G ETLEG T+E+GC GD +T+NG +++ KDI+
Sbjct: 301 EALRDLLNNHILKSAMCAEAIVAGLSVETLEGTTLEVGCSGDMLTINGKAIISNKDILAT 360
Query: 355 NGVIHLIDQVLIPDSAKQVIELAGKQQ-TTFTDLVAQLGLASALRPDGEYTLLAPVNNAF 413
NGVIH ID++LIPDSAK + ELA + +T DL Q GL + L TLLAP+N+ F
Sbjct: 361 NGVIHYIDELLIPDSAKTLFELAAESDVSTAIDLFRQAGLGNHLSGSERLTLLAPLNSVF 420
Query: 414 SDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCM 473
D T +D L L+NHI+K ++ LY+GQ LET+GGK+LRVFVYR ++CIENSC+
Sbjct: 421 KDGTPPIDAHTRNL-LRNHIIKDQLASKYLYHGQTLETLGGKKLRVFVYRNSLCIENSCI 479
Query: 474 EKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTL 533
K+GR G + ++ P ++ + LK D RFS ++ +++A L E L + G +T+
Sbjct: 480 AAHDKRGRYGTLFTMDRVLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTV 539
Query: 534 FVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKI 593
F PTN+AF+ + E+ L+ D L NI+ YH+ + + G G LK+ QG K+
Sbjct: 540 FAPTNEAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGGI--GALVRLKSLQGDKL 597
Query: 594 FLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYP 630
+ N+ + VN+ E DIM TNGV+HV+ +L P
Sbjct: 598 EVSLKNNVVSVNKEPVAEPDIMATNGVVHVITNVLQP 634
Score = 102 bits (253), Expect = 2e-21
Identities = 101/399 (25%), Positives = 174/399 (43%), Gaps = 33/399 (8%)
Query: 119 ASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKD 178
AS L +EG G +T AP+NEA++ + S+ + + L + L++H++ M +
Sbjct: 262 ASGLNTMLEGNGQYTLLAPTNEAFEKIPSETLNRILGDPEA-LRDLLNNHILKSAMCAEA 320
Query: 179 LKNGMIIPSMYNNLGLFINHYPNG-VVTVNCARIIHGNQI-ATNGVVHVIDRVLTQIGTS 236
+ G+ + ++ G + +G ++T+N II I ATNGV+H ID +L
Sbjct: 321 IVAGLSVETLE---GTTLEVGCSGDMLTINGKAIISNKDILATNGVIHYIDELLIPDSAK 377
Query: 237 IQDFIEAEDDLSS----FRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMG 292
+ AE D+S+ FR A + + L TL AP N F+ +
Sbjct: 378 TLFELAAESDVSTAIDLFRQAGLGNH----LSGSERLTLLAPLNSVFKDGTPPI------ 427
Query: 293 DKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIV 352
+ L++ HI+ S+ + G ETL G + + +S+ + + D
Sbjct: 428 -DAHTRNLLRNHIIKDQLASKYLYHGQTLETLGGKKLRVFVYRNSLCIEN-SCIAAHDKR 485
Query: 353 TNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQL---GLASALRPDGEYTLLAPV 409
G + +D+VL P + L G + F+ LVA + GL L +G YT+ AP
Sbjct: 486 GRYGTLFTMDRVLTPPMGTVMDVLKGDNR--FSMLVAAIQSAGLTETLNREGVYTVFAPT 543
Query: 410 NNAFSDDTLSMDQRLLKLILQ-NHILKVKVGLNELYNGQI-----LETIGGKQLRVFVYR 463
N AF RLL + +ILK +G L +G I L+++ G +L V +
Sbjct: 544 NEAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGGIGALVRLKSLQGDKLEVSLKN 603
Query: 464 TAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEK 502
V + + + NG +H+ +++P E+
Sbjct: 604 NVVSVNKEPVAEPDIMATNGVVHVITNVLQPPANRPQER 642
>gi|61743980 stabilin 2 precursor [Homo sapiens]
Length = 2551
Score = 73.9 bits (180), Expect = 6e-13
Identities = 71/271 (26%), Positives = 123/271 (45%), Gaps = 27/271 (9%)
Query: 110 ATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHM 169
A R+ + + L+ + + T PS +A +++D D + S N+ L + HM
Sbjct: 1007 AAIFNRWINNASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPAL--IKYHM 1064
Query: 170 INKRMLTKDLK----NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHV 225
+ DL+ + M+ S+ N +G +T+ A I+ G+ ATNGV+H+
Sbjct: 1065 LLGTYRVADLQTLSSSDMLATSLQGNFLHLAK--VDGNITIEGASIVDGDNAATNGVIHI 1122
Query: 226 IDRVLT---QIGTSIQDF---IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAF 279
I++VL ++ S+ + +E D S FR I ++ A+ +T+FAP N A
Sbjct: 1123 INKVLVPQRRLTGSLPNLLMRLEQMPDYSIFRGYIIQYNLANAIEAADAYTVFAPNNNAI 1182
Query: 280 EKLPRGVLERIMGDKVAS--EALMKYH-ILNTLQCSESIMGGAVFETLEGNT--IEIGCD 334
E I KV S E +++YH +L + G ET+ G + +
Sbjct: 1183 ENY-------IREKKVLSLEEDVLRYHVVLEEKLLKNDLHNGMHRETMLGFSYFLSFFLH 1235
Query: 335 GDSITVNGIKMVNKKDIVTNNGVIHLIDQVL 365
D + VN +N ++ T+ GVIH + +VL
Sbjct: 1236 NDQLYVNEAP-INYTNVATDKGVIHGLGKVL 1265
Score = 64.3 bits (155), Expect = 4e-10
Identities = 66/281 (23%), Positives = 117/281 (41%), Gaps = 26/281 (9%)
Query: 375 ELAGKQQTTFTDLVAQLGLASA--LRPDGEYTLLAPVNNA---FSDDTLSMDQRLLKLIL 429
E GK Q T ++ L A A L G +T+L P + F+ + L +D + + +
Sbjct: 375 EPRGKWQGRLTSFISLLDKAYAWPLSKLGPFTVLLPTDKGLKGFNVNELLVDNKAAQYFV 434
Query: 430 QNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGR-------- 481
+ HI+ ++ + + N + T+ GK +F I+ + G K+ +
Sbjct: 435 KLHIIAGQMNIEYMNNTDMFYTLTGKSGEIFNSDKDNQIKLK-LHGGKKKVKIIQGDIIA 493
Query: 482 -NGAIHIFREIIKPAEKSLHEKLKQ------DKRFSTFLSLLEAADLKELLTQPG---DW 531
NG +HI + E + +Q R+S F SLLE +L L + G +
Sbjct: 494 SNGLLHILDRAMDKLEPTFESNNEQTIMTMLQPRYSKFRSLLEETNLGHALDEDGVGGPY 553
Query: 532 TLFVPTNDAFKGMTSEEKEILIRDKNA--LQNIILYHLTPGVFIGKGFEPGVTNILKTTQ 589
T+FVP N+A M + L+ + + L ++ YH+ P + +I
Sbjct: 554 TIFVPNNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMAN 613
Query: 590 GSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYP 630
F N +L N++ +E +I NG I+ + +L P
Sbjct: 614 QLIQFNTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIP 654
Score = 62.4 bits (150), Expect = 2e-09
Identities = 68/284 (23%), Positives = 124/284 (43%), Gaps = 53/284 (18%)
Query: 246 DLSSFRAAAI------TSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEA 299
+LS AAI + + L + T+ P+ +A E + + + A
Sbjct: 1000 ELSFLSEAAIFNRWINNASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIP-A 1058
Query: 300 LMKYHIL---------NTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKD 350
L+KYH+L TL S+ + +L+GN + + +IT+ G +V+ +
Sbjct: 1059 LIKYHMLLGTYRVADLQTLSSSDMLA-----TSLQGNFLHLAKVDGNITIEGASIVDGDN 1113
Query: 351 IVTNNGVIHLIDQVLIPDSAKQVIELAGK------------QQTTFTDLVAQLGLASALR 398
TN GVIH+I++VL+P L G + F + Q LA+A+
Sbjct: 1114 AATN-GVIHIINKVLVPQR-----RLTGSLPNLLMRLEQMPDYSIFRGYIIQYNLANAIE 1167
Query: 399 PDGEYTLLAPVNNAFSD-----DTLSMDQRLLK--LILQNHILKVKVGLNELYNGQILET 451
YT+ AP NNA + LS+++ +L+ ++L+ +LK N+L+NG ET
Sbjct: 1168 AADAYTVFAPNNNAIENYIREKKVLSLEEDVLRYHVVLEEKLLK-----NDLHNGMHRET 1222
Query: 452 IGGKQ--LRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIK 493
+ G L F++ + + + + + G IH ++++
Sbjct: 1223 MLGFSYFLSFFLHNDQLYVNEAPINYTNVATDKGVIHGLGKVLE 1266
Score = 60.5 bits (145), Expect = 6e-09
Identities = 45/178 (25%), Positives = 87/178 (48%), Gaps = 14/178 (7%)
Query: 210 RIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIE------AEDDLSSFRAAAITSDILEAL 263
+II G+ IA+NG++H++DR + ++ + + E + S FR+ +++ AL
Sbjct: 485 KIIQGDIIASNGLLHILDRAMDKLEPTFESNNEQTIMTMLQPRYSKFRSLLEETNLGHAL 544
Query: 264 GRD---GHFTLFAPTNEAFEKLPRGVLERIMGDKVASE--ALMKYHILNTLQCS-ESIMG 317
D G +T+F P NEA + G L+ ++ + + + L++YHI+ Q +++
Sbjct: 545 DEDGVGGPYTIFVPNNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLIS 604
Query: 318 GAVFETLEGNTIEIG-CDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVI 374
++ I+ D I N + M + +I NG I+ + VLIP S ++
Sbjct: 605 TPHIRSMANQLIQFNTTDNGQILANDVAM-EEIEITAKNGRIYTLTGVLIPPSIVPIL 661
Score = 55.5 bits (132), Expect = 2e-07
Identities = 61/264 (23%), Positives = 109/264 (41%), Gaps = 27/264 (10%)
Query: 384 FTDLVAQLGLASALRPDGEYTLLAPVNNAFSD-----DTLSMDQRLLKLILQNHILKVK- 437
F + L L T+L P A D + + Q + +++ H+L
Sbjct: 1010 FNRWINNASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPALIKYHMLLGTY 1069
Query: 438 --VGLNELYNGQILET-IGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKP 494
L L + +L T + G L + + IE + + G NG IHI +++ P
Sbjct: 1070 RVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLVP 1129
Query: 495 AEK------SLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEE 548
+ +L +L+Q +S F + +L + +T+F P N+A + E+
Sbjct: 1130 QRRLTGSLPNLLMRLEQMPDYSIFRGYIIQYNLANAIEAADAYTVFAPNNNAIENYIREK 1189
Query: 549 KEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNIL--KTTQGSKIFLKEV--NDTLLV 604
K + + + +++ YH+ V K + + N + +T G FL ND L V
Sbjct: 1190 KVLSLEE-----DVLRYHV---VLEEKLLKNDLHNGMHRETMLGFSYFLSFFLHNDQLYV 1241
Query: 605 NELKSKESDIMTTNGVIHVVDKLL 628
NE +++ T GVIH + K+L
Sbjct: 1242 NEAPINYTNVATDKGVIHGLGKVL 1265
Score = 53.1 bits (126), Expect = 1e-06
Identities = 45/156 (28%), Positives = 82/156 (52%), Gaps = 12/156 (7%)
Query: 498 SLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKN 557
S++++L ++ + S + L+ +K+L+ PG +T+F P + AF EE + DK
Sbjct: 1598 SIYQELPKNPKTSQYFFQLQEHFVKDLVG-PGPFTVFAPLSAAF----DEEARVKDWDKY 1652
Query: 558 ALQ-NIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVN-ELKSKESDIM 615
L ++ YH+ + ++N + QG I + T+ +N + K SDI+
Sbjct: 1653 GLMPQVLRYHVVACHQLLLENLKLISNAT-SLQGEPIVISVSQSTVYINNKAKIISSDII 1711
Query: 616 TTNGVIHVVDKLLYPAD---TPVGND-QLLEILNKL 647
+TNG++H++DKLL P + TP N ++L+ L L
Sbjct: 1712 STNGIVHIIDKLLSPKNLLITPKDNSGRILQNLTTL 1747
Score = 51.6 bits (122), Expect = 3e-06
Identities = 65/271 (23%), Positives = 122/271 (45%), Gaps = 38/271 (14%)
Query: 124 EEIEGKGSFTYFAPSNEAWDN----LDSDIRRGLESNVNVELLNALHSHMINKRMLTKDL 179
+++ G G FT FAP + A+D D D + GL V L H++ L L
Sbjct: 1622 KDLVGPGPFTVFAPLSAAFDEEARVKDWD-KYGLMPQV-------LRYHVVACHQLL--L 1671
Query: 180 KNGMIIPSMYNNLG--LFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLT------ 231
+N +I + + G + I+ + V N A+II + I+TNG+VH+ID++L+
Sbjct: 1672 ENLKLISNATSLQGEPIVISVSQSTVYINNKAKIISSDIISTNGIVHIIDKLLSPKNLLI 1731
Query: 232 ----QIGTSIQDF--IEAEDDLSSFRAAAITSDILEALGRDGH--FTLFAPTNEAFEKLP 283
G +Q+ + + F S +L + H TLF PT++A LP
Sbjct: 1732 TPKDNSGRILQNLTTLATNNGYIKFSNLIQDSGLLSVITDPIHTPVTLFWPTDQALHALP 1791
Query: 284 RGVLERIMG--DKVASEALMKYHILNTLQ-CSESIMGGAVFETLEGNTIEIGCD-----G 335
+ + +K + +K+H++ + + + ++TL+G+ + + C G
Sbjct: 1792 AEQQDFLFNQDNKDKLKEYLKFHVIRDAKVLAVDLPTSTAWKTLQGSELSVKCGAGRDIG 1851
Query: 336 DSITVNGIKMVNKKDIVTNNGVIHLIDQVLI 366
D + +++++ + GV + ID +LI
Sbjct: 1852 DLFLNGQTCRIVQRELLFDLGVAYGIDCLLI 1882
Score = 50.1 bits (118), Expect = 9e-06
Identities = 37/142 (26%), Positives = 69/142 (48%), Gaps = 5/142 (3%)
Query: 519 ADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFE 578
A L+ L+ + T+ VP+ A + M +EK + N + +I YH+ G + +
Sbjct: 1017 ASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSN-IPALIKYHMLLGTYRVADLQ 1075
Query: 579 P-GVTNILKTT-QGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVG 636
+++L T+ QG+ + L +V+ + + + D TNGVIH+++K+L P G
Sbjct: 1076 TLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLVPQRRLTG 1135
Query: 637 NDQLLEILNKLIKYIQIKFVRG 658
+ L +L +L + RG
Sbjct: 1136 S--LPNLLMRLEQMPDYSIFRG 1155
Score = 48.1 bits (113), Expect = 3e-05
Identities = 52/225 (23%), Positives = 101/225 (44%), Gaps = 42/225 (18%)
Query: 267 GHFTLFAPTNEAFEKLPR-------GVLERIMGDKVASEALMKYHILNTLQCS-ESIMGG 318
G FT+FAP + AF++ R G++ +++ +YH++ Q E++
Sbjct: 1628 GPFTVFAPLSAAFDEEARVKDWDKYGLMPQVL----------RYHVVACHQLLLENLKLI 1677
Query: 319 AVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIP--------DSA 370
+ +L+G I I ++ +N + DI++ NG++H+ID++L P D++
Sbjct: 1678 SNATSLQGEPIVISVSQSTVYINNKAKIISSDIISTNGIVHIIDKLLSPKNLLITPKDNS 1737
Query: 371 KQVIELAGKQQTT-----FTDLVAQLGLASALRP--DGEYTLLAPVNNAF-------SDD 416
++++ T F++L+ GL S + TL P + A D
Sbjct: 1738 GRILQNLTTLATNNGYIKFSNLIQDSGLLSVITDPIHTPVTLFWPTDQALHALPAEQQDF 1797
Query: 417 TLSMDQR-LLKLILQNHILK-VKVGLNELYNGQILETIGGKQLRV 459
+ D + LK L+ H+++ KV +L +T+ G +L V
Sbjct: 1798 LFNQDNKDKLKEYLKFHVIRDAKVLAVDLPTSTAWKTLQGSELSV 1842
Score = 47.8 bits (112), Expect = 4e-05
Identities = 54/255 (21%), Positives = 115/255 (45%), Gaps = 28/255 (10%)
Query: 401 GEYTLLAPVNNAFSDDTLSMD---QRLLKLILQNHILKV-KVGLNELYNGQILETIGGKQ 456
G +T+ AP++ AF ++ D L+ +L+ H++ ++ L L ++ G+
Sbjct: 1628 GPFTVFAPLSAAFDEEARVKDWDKYGLMPQVLRYHVVACHQLLLENLKLISNATSLQGEP 1687
Query: 457 LRVFVYRTAVCIENSCMEKGSKQ-GRNGAIHIFREIIKPAEKSLHEK------------L 503
+ + V ++ V I N S NG +HI +++ P + K L
Sbjct: 1688 IVISVSQSTVYINNKAKIISSDIISTNGIVHIIDKLLSPKNLLITPKDNSGRILQNLTTL 1747
Query: 504 KQDKRFSTFLSLLEAADLKELLTQP--GDWTLFVPTNDAFKGMTSEEKEILIR--DKNAL 559
+ + F +L++ + L ++T P TLF PT+ A + +E+++ L +K+ L
Sbjct: 1748 ATNNGYIKFSNLIQDSGLLSVITDPIHTPVTLFWPTDQALHALPAEQQDFLFNQDNKDKL 1807
Query: 560 QNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLK-----EVNDTLLVNE-LKSKESD 613
+ + +H+ + + + KT QGS++ +K ++ D L + + + +
Sbjct: 1808 KEYLKFHVIRDAKV-LAVDLPTSTAWKTLQGSELSVKCGAGRDIGDLFLNGQTCRIVQRE 1866
Query: 614 IMTTNGVIHVVDKLL 628
++ GV + +D LL
Sbjct: 1867 LLFDLGVAYGIDCLL 1881
Score = 33.9 bits (76), Expect = 0.64
Identities = 33/111 (29%), Positives = 46/111 (41%), Gaps = 20/111 (18%)
Query: 532 TLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTP-GVFIGKGFEPGVTNILKTTQG 590
TLFVP N E + + RD I +HL +F G T L+T G
Sbjct: 2356 TLFVPQNSGL----GENETLSGRD-------IEHHLANVSMFFYNDLVNGTT--LQTRLG 2402
Query: 591 SKIFLKEVNDTLLVNELKSKES------DIMTTNGVIHVVDKLLYPADTPV 635
SK+ + D L E + + DI +NG+IHV+ + L PV
Sbjct: 2403 SKLLITASQDPLQPTETRFVDGRAILQWDIFASNGIIHVISRPLKAPPAPV 2453
Score = 30.4 bits (67), Expect = 7.1
Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 3/103 (2%)
Query: 130 GSFTYFAPSNEAWDNL-DSDIRRGLESNVNVELLNALHSHMINKRML-TKDLKNGMIIPS 187
G +T F P+NEA +N+ D + L + +LL + H++ L L + I S
Sbjct: 551 GPYTIFVPNNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRS 610
Query: 188 MYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVL 230
M N L F N NG + N + A NG ++ + VL
Sbjct: 611 MANQLIQF-NTTDNGQILANDVAMEEIEITAKNGRIYTLTGVL 652
>gi|61743978 stabilin 1 precursor [Homo sapiens]
Length = 2570
Score = 59.3 bits (142), Expect = 1e-08
Identities = 73/294 (24%), Positives = 123/294 (41%), Gaps = 40/294 (13%)
Query: 392 GLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILE- 450
G L G +T+L P ++FS T M+ L + + + HI+ + L + Q
Sbjct: 386 GCREILTTAGPFTVLVPSVSSFSSRT--MNASLAQQLCRQHIIAGQHILEDTRTQQTRRW 443
Query: 451 -TIGGKQLRV-------FVYRTAVCIENSC-MEKGSKQGRNGAIHIFREIIKPA------ 495
T+ G+++ V + Y+ + + + K + NG H+ + A
Sbjct: 444 WTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANNIAANGVFHVVTGLRWQAPSGTPG 503
Query: 496 --EKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILI 553
++++ + L + FS F ++LE L +L PG +T+F P+N+A + L
Sbjct: 504 DPKRTIGQILASTEAFSRFETILENCGLPSILDGPGPFTVFAPSNEAVDSLRDGRLIYLF 563
Query: 554 -RDKNALQNIILYH------LTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNE 606
+ LQ ++ YH LT I KG + Q + + E LL E
Sbjct: 564 TAGLSKLQELVRYHIYNHGQLTVEKLISKG-----RILTMANQVLAVNISEEGRILLGPE 618
Query: 607 -LKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGS 659
+ + D+M NGVIH++D +L P +L IL K Q K V GS
Sbjct: 619 GVPLQRVDVMAANGVIHMLDGILLP-------PTILPILPKHCSEEQHKIVAGS 665
Score = 59.3 bits (142), Expect = 1e-08
Identities = 47/176 (26%), Positives = 82/176 (46%), Gaps = 12/176 (6%)
Query: 211 IIHGNQIATNGVVHVIDRVLTQI--GT------SIQDFIEAEDDLSSFRAAAITSDILEA 262
I N IA NGV HV+ + Q GT +I + + + S F +
Sbjct: 475 IYKANNIAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSI 534
Query: 263 LGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVAS-EALMKYHILNTLQCS-ESIMGGAV 320
L G FT+FAP+NEA + L G L + ++ + L++YHI N Q + E ++
Sbjct: 535 LDGPGPFTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGR 594
Query: 321 FETLEGNTIEIGCDGDSITVNGIKMV--NKKDIVTNNGVIHLIDQVLIPDSAKQVI 374
T+ + + + + G + V + D++ NGVIH++D +L+P + ++
Sbjct: 595 ILTMANQVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPIL 650
Score = 50.8 bits (120), Expect = 5e-06
Identities = 58/226 (25%), Positives = 94/226 (41%), Gaps = 32/226 (14%)
Query: 266 DGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQC-SESIMGGAVFETL 324
DG FT+F P + L + L RI + + + +YH++ + SE ++ L
Sbjct: 1611 DGPFTIFVPHADLMSNLSQDELARIRAHR---QLVFRYHVVGCRRLRSEDLLEQGYATAL 1667
Query: 325 EGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSA------------KQ 372
G+ + SI +N V D NG++H ID+VL+P A +
Sbjct: 1668 SGHPLRFSEREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDDAPIPRRN 1727
Query: 373 VIELA-GKQQTTFTDLVAQLGLASALRPDGE--YTLLAPVNNAFSDDTLSMDQRL----- 424
V A G F+ L+ GL LR +T+L P + AF L D++
Sbjct: 1728 VTAAAQGFGYKIFSGLLKVAGLLPLLREASHRPFTMLWPTDAAFR--ALPPDRQAWLYHE 1785
Query: 425 -----LKLILQNHILK-VKVGLNELYNGQILETIGGKQLRVFVYRT 464
L IL+ H+++ V+ ++L N L T+ G + RT
Sbjct: 1786 DHRDKLAAILRGHMIRNVEALASDLPNLGPLRTMHGTPISFSCSRT 1831
Score = 48.5 bits (114), Expect = 3e-05
Identities = 60/268 (22%), Positives = 113/268 (42%), Gaps = 31/268 (11%)
Query: 124 EEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMIN-KRMLTKDLKNG 182
+E++G G FT F P + NL D + ++ + H++ +R+ ++DL
Sbjct: 1606 KELKGDGPFTIFVPHADLMSNLSQDELARIRAHRQL----VFRYHVVGCRRLRSEDLLEQ 1661
Query: 183 MIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIE 242
++ + L + + + AR++ + A NG++H IDRVL + +
Sbjct: 1662 GYATALSGH-PLRFSEREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDD 1720
Query: 243 AEDDLSSFRAAA------ITSDILEALG-----RDGH---FTLFAPTNEAFEKLP----R 284
A + AAA I S +L+ G R+ FT+ PT+ AF LP
Sbjct: 1721 APIPRRNVTAAAQGFGYKIFSGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQA 1780
Query: 285 GVLERIMGDKVASEALMKYHILNTLQCSESIMGG-AVFETLEGNTIEIGCD----GDSIT 339
+ DK+A A+++ H++ ++ S + T+ G I C G+ +
Sbjct: 1781 WLYHEDHRDKLA--AILRGHMIRNVEALASDLPNLGPLRTMHGTPISFSCSRTRAGELMV 1838
Query: 340 VNGIKMVNKKDIVTNNGVIHLIDQVLIP 367
+ ++ + G+ + IDQ+L P
Sbjct: 1839 GEDDARIVQRHLPFEGGLAYGIDQLLEP 1866
Score = 42.4 bits (98), Expect = 0.002
Identities = 32/150 (21%), Positives = 69/150 (46%), Gaps = 10/150 (6%)
Query: 499 LHEKLKQDKRFSTFLSLLEAADLKELLTQPGDW--TLFVPTNDAFKGMTSEEKEILIRDK 556
+ +L+ + FS F L++A + T P D T VP+ A + ++ E++ ++ +
Sbjct: 991 IFRELEANAHFSIFYQWLKSAGI----TLPADRRVTALVPSEAAVRQLSPEDRAFWLQPR 1046
Query: 557 NALQNIILYHLTPGVFIGKGFEP-GVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIM 615
L N++ H G + G + ++ ++ ++ + V +D++
Sbjct: 1047 T-LPNLVRAHFLQGALFEEELARLGGQEVATLNPTTRWEIRNISGRVWVQNASVDVADLL 1105
Query: 616 TTNGVIHVVDKLLYP--ADTPVGNDQLLEI 643
TNGV+H++ ++L P D P G L ++
Sbjct: 1106 ATNGVLHILSQVLLPPRGDVPGGQGLLQQL 1135
Score = 40.4 bits (93), Expect = 0.007
Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Query: 126 IEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLT--KDLKNGM 183
++G G FT FAPSNEA D+L L + +L + H+ N LT K + G
Sbjct: 535 LDGPGPFTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGR 594
Query: 184 IIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVL 230
I+ L + I+ ++ + + +A NGV+H++D +L
Sbjct: 595 ILTMANQVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGIL 641
Score = 38.1 bits (87), Expect = 0.034
Identities = 37/135 (27%), Positives = 61/135 (45%), Gaps = 14/135 (10%)
Query: 502 KLKQDKRFSTF-LSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQ 560
+L +DK S F L LLE +LK G +T+FVP D ++ +E L R + Q
Sbjct: 1588 ELLRDKHASFFSLRLLEYKELKG----DGPFTIFVPHADLMSNLSQDE---LARIRAHRQ 1640
Query: 561 NIILYHLTPGVFIGKG--FEPGVTNILKTTQGSKIFLKEVNDTLLVNEL-KSKESDIMTT 617
+ YH+ + E G L G + E ++ +N+ + SD
Sbjct: 1641 LVFRYHVVGCRRLRSEDLLEQGYATALS---GHPLRFSEREGSIYLNDFARVVSSDHEAV 1697
Query: 618 NGVIHVVDKLLYPAD 632
NG++H +D++L P +
Sbjct: 1698 NGILHFIDRVLLPPE 1712
Score = 34.7 bits (78), Expect = 0.38
Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 6/79 (7%)
Query: 466 VCIENSCMEKGSKQGRNGAIHIFREIIKPAE------KSLHEKLKQDKRFSTFLSLLEAA 519
V ++N+ ++ NG +HI +++ P + L ++L FS F LL+
Sbjct: 1092 VWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPAFSLFRELLQHH 1151
Query: 520 DLKELLTQPGDWTLFVPTN 538
L + +T+FVPTN
Sbjct: 1152 GLVPQIEAATAYTIFVPTN 1170
Score = 33.9 bits (76), Expect = 0.64
Identities = 32/124 (25%), Positives = 52/124 (41%), Gaps = 13/124 (10%)
Query: 300 LMKYHILNTLQCSESI--MGGAVFETLEGNTI-EIGCDGDSITVNGIKMVNKKDIVTNNG 356
L++ H L E + +GG TL T EI + V V+ D++ NG
Sbjct: 1051 LVRAHFLQGALFEEELARLGGQEVATLNPTTRWEIRNISGRVWVQNAS-VDVADLLATNG 1109
Query: 357 VIHLIDQVLIP--------DSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAP 408
V+H++ QVL+P Q ++L + F +L+ GL + YT+ P
Sbjct: 1110 VLHILSQVLLPPRGDVPGGQGLLQQLDLV-PAFSLFRELLQHHGLVPQIEAATAYTIFVP 1168
Query: 409 VNNA 412
N +
Sbjct: 1169 TNRS 1172
Score = 32.0 bits (71), Expect = 2.4
Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 6/86 (6%)
Query: 201 NGVVTVNCARIIHGNQIATNGVVHVIDRVL------TQIGTSIQDFIEAEDDLSSFRAAA 254
+G V V A + + +ATNGV+H++ +VL G + ++ S FR
Sbjct: 1089 SGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPAFSLFRELL 1148
Query: 255 ITSDILEALGRDGHFTLFAPTNEAFE 280
++ + +T+F PTN + E
Sbjct: 1149 QHHGLVPQIEAATAYTIFVPTNRSLE 1174
>gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]
Length = 445
Score = 33.9 bits (76), Expect = 0.64
Identities = 21/101 (20%), Positives = 52/101 (51%), Gaps = 6/101 (5%)
Query: 409 VNNAFSDDTLSMDQRLLKLILQNHILKVKV-GLNELYNGQILETIGGKQLRVFVYRTAVC 467
+N+A + D++ + + L+ + L+N +K ++ L + Y ++ + KQ ++ V +
Sbjct: 163 MNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEAS-MDKLREKQRQLEVAQ---- 217
Query: 468 IENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKR 508
+EN ++ + + + RE+ K EKL++++R
Sbjct: 218 VENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQR 258
>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
Length = 550
Score = 33.9 bits (76), Expect = 0.64
Identities = 21/101 (20%), Positives = 52/101 (51%), Gaps = 6/101 (5%)
Query: 409 VNNAFSDDTLSMDQRLLKLILQNHILKVKV-GLNELYNGQILETIGGKQLRVFVYRTAVC 467
+N+A + D++ + + L+ + L+N +K ++ L + Y ++ + KQ ++ V +
Sbjct: 163 MNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEAS-MDKLREKQRQLEVAQ---- 217
Query: 468 IENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKR 508
+EN ++ + + + RE+ K EKL++++R
Sbjct: 218 VENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQR 258
>gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]
Length = 438
Score = 33.9 bits (76), Expect = 0.64
Identities = 21/101 (20%), Positives = 52/101 (51%), Gaps = 6/101 (5%)
Query: 409 VNNAFSDDTLSMDQRLLKLILQNHILKVKV-GLNELYNGQILETIGGKQLRVFVYRTAVC 467
+N+A + D++ + + L+ + L+N +K ++ L + Y ++ + KQ ++ V +
Sbjct: 163 MNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEAS-MDKLREKQRQLEVAQ---- 217
Query: 468 IENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKR 508
+EN ++ + + + RE+ K EKL++++R
Sbjct: 218 VENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQR 258
>gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]
Length = 466
Score = 33.9 bits (76), Expect = 0.64
Identities = 21/101 (20%), Positives = 52/101 (51%), Gaps = 6/101 (5%)
Query: 409 VNNAFSDDTLSMDQRLLKLILQNHILKVKV-GLNELYNGQILETIGGKQLRVFVYRTAVC 467
+N+A + D++ + + L+ + L+N +K ++ L + Y ++ + KQ ++ V +
Sbjct: 163 MNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEAS-MDKLREKQRQLEVAQ---- 217
Query: 468 IENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKR 508
+EN ++ + + + RE+ K EKL++++R
Sbjct: 218 VENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQR 258
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 33.1 bits (74), Expect = 1.1
Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 5/98 (5%)
Query: 730 IKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLLQEEVTKVTK 789
++K + ++ EI KE ++R+I + R+ T GE + L E+ T V++
Sbjct: 1249 LEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGE----YSRQLDEKDTLVSQ 1304
Query: 790 FIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSR 827
G + EE+KR L+ + + A+ +Q SR
Sbjct: 1305 LSRGKQAFTQQIEELKRQLEEEIKAKSALAH-ALQSSR 1341
>gi|50843820 sickle tail isoform 1 [Homo sapiens]
Length = 1943
Score = 32.3 bits (72), Expect = 1.9
Identities = 31/127 (24%), Positives = 55/127 (43%), Gaps = 17/127 (13%)
Query: 670 TTKIITKVVEPKIKVIE-GSLQPIIKTEGPTLTKVKIEGEPEFRLIKEGETITEVIHGEP 728
T I + E ++V+ G + I+ +G + V I+ E +EG + +P
Sbjct: 1380 TDNIAFMITETTVQVLSSGEVHDIVSQKGEDIQTVNIDARKEMTPRQEGTD-----NEDP 1434
Query: 729 IIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLLQEEVTKVT 788
++ +D PV I E + R Y R+ST E +E L++++ EE +
Sbjct: 1435 VV-----CLDKKPVIIIFDEPMDIRSA------YKRLSTIFEECDEELERMMMEEKIEEE 1483
Query: 789 KFIEGGD 795
+ E GD
Sbjct: 1484 EEEENGD 1490
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 32.3 bits (72), Expect = 1.9
Identities = 22/90 (24%), Positives = 41/90 (45%), Gaps = 4/90 (4%)
Query: 731 KKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLLQEEVTKVTKF 790
+K + ++ EI KE ++R+I + R+ T GE + L E+ V++
Sbjct: 1250 EKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGE----FSRQLDEKDAMVSQL 1305
Query: 791 IEGGDGHLFEDEEIKRLLQGDTPVRKLQAN 820
G + EE+KR L+ +T + A+
Sbjct: 1306 SRGKQAFTQQIEELKRQLEEETKAKSTLAH 1335
>gi|93102367 ral guanine nucleotide dissociation stimulator-like 1
[Homo sapiens]
Length = 803
Score = 32.0 bits (71), Expect = 2.4
Identities = 44/177 (24%), Positives = 76/177 (42%), Gaps = 26/177 (14%)
Query: 225 VIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPR 284
+++ +LT G + DF LS++R A T ++LE L D + L +P E
Sbjct: 112 LVENLLTAFGDN--DFTYISIFLSTYRGFASTKEVLELL-LDRYGNLTSPNCEEDGSQSS 168
Query: 285 GVLERIMGDKVASEALMKYHILNTL--QCSESIMGGAVFETLEG-----NTIEIGCDGDS 337
+ ++ + +AS IL QC+E F L+ + G D +
Sbjct: 169 SESKMVIRNAIAS-------ILRAWLDQCAEDFREPPHFPCLQKLLDYLTRMMPGSDPER 221
Query: 338 ITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFT----DLVAQ 390
N ++ K+++ T+NG+ + I S ++ EL G + FT DLVA+
Sbjct: 222 RAQNLLEQFQKQEVETDNGLPNTIS-----FSLEEEEELEGGESAEFTCFSEDLVAE 273
>gi|131889097 cancer susceptibility candidate 1 isoform b [Homo
sapiens]
Length = 716
Score = 32.0 bits (71), Expect = 2.4
Identities = 37/160 (23%), Positives = 72/160 (45%), Gaps = 17/160 (10%)
Query: 671 TKIITKVVEPKIKVIEGSLQPIIKTEGPTL-TKVKIEGEPEFRLIKEGETITEVIHGEPI 729
T+I+ K + G+++ +IK E TL ++ P R ++ ET I
Sbjct: 184 TEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSET--------QI 235
Query: 730 IKKYTKIIDGVPVEITEKETREERI-----ITGPEIKYTRISTGGGETE-ETLKKLLQEE 783
+ +I+ + + T + + ++ P +YT T + + + ++K + +E
Sbjct: 236 GFEIPRILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKE 295
Query: 784 VTKVTKFIEGGDGHLFEDEEIK-RLLQGDTPVRKLQANKK 822
V + +K E G HL ++EEIK QGD V+ A ++
Sbjct: 296 VEEESKQQERGS-HLIQEEEIKVEEEQGDIEVKMSSAEEE 334
>gi|131889447 cancer susceptibility candidate 1 isoform c [Homo
sapiens]
Length = 690
Score = 32.0 bits (71), Expect = 2.4
Identities = 37/160 (23%), Positives = 72/160 (45%), Gaps = 17/160 (10%)
Query: 671 TKIITKVVEPKIKVIEGSLQPIIKTEGPTL-TKVKIEGEPEFRLIKEGETITEVIHGEPI 729
T+I+ K + G+++ +IK E TL ++ P R ++ ET I
Sbjct: 248 TEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSET--------QI 299
Query: 730 IKKYTKIIDGVPVEITEKETREERI-----ITGPEIKYTRISTGGGETE-ETLKKLLQEE 783
+ +I+ + + T + + ++ P +YT T + + + ++K + +E
Sbjct: 300 GFEIPRILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKE 359
Query: 784 VTKVTKFIEGGDGHLFEDEEIK-RLLQGDTPVRKLQANKK 822
V + +K E G HL ++EEIK QGD V+ A ++
Sbjct: 360 VEEESKQQERGS-HLIQEEEIKVEEEQGDIEVKMSSAEEE 398
>gi|131888105 cancer susceptibility candidate 1 isoform a [Homo
sapiens]
Length = 722
Score = 32.0 bits (71), Expect = 2.4
Identities = 37/160 (23%), Positives = 72/160 (45%), Gaps = 17/160 (10%)
Query: 671 TKIITKVVEPKIKVIEGSLQPIIKTEGPTL-TKVKIEGEPEFRLIKEGETITEVIHGEPI 729
T+I+ K + G+++ +IK E TL ++ P R ++ ET I
Sbjct: 190 TEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSET--------QI 241
Query: 730 IKKYTKIIDGVPVEITEKETREERI-----ITGPEIKYTRISTGGGETE-ETLKKLLQEE 783
+ +I+ + + T + + ++ P +YT T + + + ++K + +E
Sbjct: 242 GFEIPRILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKE 301
Query: 784 VTKVTKFIEGGDGHLFEDEEIK-RLLQGDTPVRKLQANKK 822
V + +K E G HL ++EEIK QGD V+ A ++
Sbjct: 302 VEEESKQQERGS-HLIQEEEIKVEEEQGDIEVKMSSAEEE 340
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 31.2 bits (69), Expect = 4.2
Identities = 43/200 (21%), Positives = 87/200 (43%), Gaps = 20/200 (10%)
Query: 593 IFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLL----YPADTPVGNDQLLEILNKLI 648
+++K+ LL +L+ + S+ M +++ +K L T V +++ ++
Sbjct: 675 VYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQME 734
Query: 649 KYIQIKFVRGSTFKEIPVTVYTTKIITKVVEPKIKVIEGSLQPIIKTEGPTLTK----VK 704
K IQ K + T +E+ T ++ TK E I+TE +LTK +K
Sbjct: 735 KCIQEKDEKLKTVEELLETGLI-QVATKEEELNA----------IRTENSSLTKEVQDLK 783
Query: 705 IEGEPEFRLIKEGETITEVIHGEP-IIKKYTKIIDGVPVEITEKETREERIITGPEIKYT 763
+ + E + +VIH + IK ++++ +++ KE + IT +
Sbjct: 784 AKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQLSITSKVQELQ 843
Query: 764 RISTGGGETEETLKKLLQEE 783
+ G E T+K +L+E+
Sbjct: 844 NLLKGKEEQMNTMKAVLEEK 863
>gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens]
Length = 763
Score = 30.8 bits (68), Expect = 5.4
Identities = 23/71 (32%), Positives = 32/71 (45%), Gaps = 13/71 (18%)
Query: 18 PINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLY 77
P+N + D IL ++ +G N CA G K S CKNW K+ C
Sbjct: 370 PLNCSEK-DHILPENQCCRVCRGHNFCAE----GPKCGENSECKNWNTKATC-------- 416
Query: 78 ECCPGYMRMEG 88
EC GY+ ++G
Sbjct: 417 ECKSGYISVQG 427
>gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens]
Length = 810
Score = 30.8 bits (68), Expect = 5.4
Identities = 23/71 (32%), Positives = 32/71 (45%), Gaps = 13/71 (18%)
Query: 18 PINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLY 77
P+N + D IL ++ +G N CA G K S CKNW K+ C
Sbjct: 370 PLNCSEK-DHILPENQCCRVCRGHNFCAE----GPKCGENSECKNWNTKATC-------- 416
Query: 78 ECCPGYMRMEG 88
EC GY+ ++G
Sbjct: 417 ECKSGYISVQG 427
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 30.8 bits (68), Expect = 5.4
Identities = 15/41 (36%), Positives = 25/41 (60%)
Query: 769 GGETEETLKKLLQEEVTKVTKFIEGGDGHLFEDEEIKRLLQ 809
G ET K LQEE++ +T + G +L E E++K+L++
Sbjct: 1506 GQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIE 1546
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 30.8 bits (68), Expect = 5.4
Identities = 23/98 (23%), Positives = 45/98 (45%), Gaps = 5/98 (5%)
Query: 730 IKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLLQEEVTKVTK 789
++K + ++ E+ KE ++R+I + R+ T GE + L E+ V++
Sbjct: 1251 LEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGE----FSRQLDEKEALVSQ 1306
Query: 790 FIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSR 827
G + EE+KR L+ + + A+ +Q SR
Sbjct: 1307 LSRGKQAFTQQIEELKRQLEEEIKAKNALAH-ALQSSR 1343
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 30.8 bits (68), Expect = 5.4
Identities = 23/98 (23%), Positives = 45/98 (45%), Gaps = 5/98 (5%)
Query: 730 IKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLLQEEVTKVTK 789
++K + ++ E+ KE ++R+I + R+ T GE + L E+ V++
Sbjct: 1251 LEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGE----FSRQLDEKEALVSQ 1306
Query: 790 FIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSR 827
G + EE+KR L+ + + A+ +Q SR
Sbjct: 1307 LSRGKQAFTQQIEELKRQLEEEIKAKNALAH-ALQSSR 1343
>gi|32130514 N-myc downstream-regulated gene 3 isoform b [Homo
sapiens]
Length = 363
Score = 30.4 bits (67), Expect = 7.1
Identities = 17/41 (41%), Positives = 24/41 (58%)
Query: 595 LKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPV 635
L++V T + L KE DI TT+GV+HV + L + PV
Sbjct: 4 LQDVQLTEIKPLLNDKEHDIETTHGVVHVTIRGLPKGNRPV 44
>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 30.4 bits (67), Expect = 7.1
Identities = 58/234 (24%), Positives = 92/234 (39%), Gaps = 41/234 (17%)
Query: 588 TQGSKIF--LKEVND--TLLVNELKSKESDIMTTNGVIHVVDKLLYP-----ADTPVGND 638
TQ KI KE+N+ +L NE+K+K D+ T ++ + K + + +
Sbjct: 339 TQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDV 398
Query: 639 QLLEIL-------NKLIKYIQIKFVRGSTFKEIPV----TVYTTKIITKVVEPKIKVIEG 687
Q+ E L KL K +Q + FK IP + T +E + + E
Sbjct: 399 QVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEK 458
Query: 688 SLQPI---IKTEGPTLTKVKIEGEPEF----RLIKEGETITEVIHGE---------PIIK 731
L+ + +K E L K K E E + + E + +V E +
Sbjct: 459 KLKEVMDSLKQETQGLQKEKESREKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVS 518
Query: 732 KYTKIIDGVPVEITEKETREER--IITGPEIKYTRISTGGGETEETLKKLLQEE 783
+ TK + + I ET +ER I E K + E E+ L+KL QEE
Sbjct: 519 QLTKAKEAL---IAASETLKERKAAIRDIEGKLPQTEQELKEKEKELQKLTQEE 569
>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 30.4 bits (67), Expect = 7.1
Identities = 58/234 (24%), Positives = 92/234 (39%), Gaps = 41/234 (17%)
Query: 588 TQGSKIF--LKEVND--TLLVNELKSKESDIMTTNGVIHVVDKLLYP-----ADTPVGND 638
TQ KI KE+N+ +L NE+K+K D+ T ++ + K + + +
Sbjct: 339 TQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDV 398
Query: 639 QLLEIL-------NKLIKYIQIKFVRGSTFKEIPV----TVYTTKIITKVVEPKIKVIEG 687
Q+ E L KL K +Q + FK IP + T +E + + E
Sbjct: 399 QVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEK 458
Query: 688 SLQPI---IKTEGPTLTKVKIEGEPEF----RLIKEGETITEVIHGE---------PIIK 731
L+ + +K E L K K E E + + E + +V E +
Sbjct: 459 KLKEVMDSLKQETQGLQKEKESREKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVS 518
Query: 732 KYTKIIDGVPVEITEKETREER--IITGPEIKYTRISTGGGETEETLKKLLQEE 783
+ TK + + I ET +ER I E K + E E+ L+KL QEE
Sbjct: 519 QLTKAKEAL---IAASETLKERKAAIRDIEGKLPQTEQELKEKEKELQKLTQEE 569
>gi|38569428 ankyrin repeat domain protein 5 [Homo sapiens]
Length = 776
Score = 30.4 bits (67), Expect = 7.1
Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 13/92 (14%)
Query: 685 IEGSLQPIIKTEGPTLTKVK-----IEGEPEFRLIKEGETITE--VIHGEPIIKK-YTKI 736
++G PI+KTEGP + K + I G P EG+ + + V+H +I YTK
Sbjct: 659 LKGKTPPILKTEGPEIKKEEELLSSIYGVP---TTSEGKKVQKGNVVHLNSLITSGYTKK 715
Query: 737 ID--GVPVEITEKETREERIITGPEIKYTRIS 766
+D +P I E +I E++ R +
Sbjct: 716 VDITFIPRRIWSPEATTAELIRKRELRRERFT 747
>gi|38569426 ankyrin repeat domain protein 5 [Homo sapiens]
Length = 776
Score = 30.4 bits (67), Expect = 7.1
Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 13/92 (14%)
Query: 685 IEGSLQPIIKTEGPTLTKVK-----IEGEPEFRLIKEGETITE--VIHGEPIIKK-YTKI 736
++G PI+KTEGP + K + I G P EG+ + + V+H +I YTK
Sbjct: 659 LKGKTPPILKTEGPEIKKEEELLSSIYGVP---TTSEGKKVQKGNVVHLNSLITSGYTKK 715
Query: 737 ID--GVPVEITEKETREERIITGPEIKYTRIS 766
+D +P I E +I E++ R +
Sbjct: 716 VDITFIPRRIWSPEATTAELIRKRELRRERFT 747
>gi|108773797 ganglioside-induced differentiation-associated protein
1 isoform a [Homo sapiens]
Length = 358
Score = 30.0 bits (66), Expect = 9.3
Identities = 32/134 (23%), Positives = 59/134 (44%), Gaps = 30/134 (22%)
Query: 655 FVRGSTFKEIPVTVYTTKIITKVVEPKIKVIEGSLQPIIKTEGPTLTKVKIEGEPEFRLI 714
F+R ++ E+PV ++ II + + +I+ Q + P RL+
Sbjct: 68 FMRLNSTGEVPVLIHGENIICEATQ----IIDYLEQTFLDERTP-------------RLM 110
Query: 715 KEGETITEVIHGEPIIKKYTKIIDGVPVE------ITEKETREERIITGPEIKYTRISTG 768
+ E++ P ++ Y +++D +P++ I E + +I P TRI +
Sbjct: 111 PDKESMYY-----PRVQHYRELLDSLPMDAYTHGCILHPELTVDSMI--PAYATTRIRSQ 163
Query: 769 GGETEETLKKLLQE 782
G TE LKKL +E
Sbjct: 164 IGNTESELKKLAEE 177
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.137 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,838,150
Number of Sequences: 37866
Number of extensions: 1327309
Number of successful extensions: 3366
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 3202
Number of HSP's gapped (non-prelim): 73
length of query: 836
length of database: 18,247,518
effective HSP length: 111
effective length of query: 725
effective length of database: 14,044,392
effective search space: 10182184200
effective search space used: 10182184200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.