Search of human proteins with 209862869

Search of human proteins with 209862869

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
[Homo sapiens]
         (724 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...  1476   0.0  
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [...  1476   0.0  
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ...  1383   0.0  
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo...   448   e-126
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ...   446   e-125
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [...   446   e-125
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]    291   1e-78
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]         283   3e-76
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]          283   3e-76
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...   273   4e-73
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   271   2e-72
gi|21071032 DEAD-box protein abstrakt [Homo sapiens]                  256   7e-68
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]            252   7e-67
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]            252   7e-67
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...   250   4e-66
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi...   244   2e-64
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...   238   2e-62
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...   208   1e-53
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi...   207   3e-53
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi...   206   8e-53
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...   206   8e-53
gi|13129006 nucleolar protein GU2 [Homo sapiens]                      196   8e-50
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...   192   1e-48
gi|7661920 eukaryotic translation initiation factor 4A, isoform ...   191   2e-48
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...   191   2e-48
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...   191   2e-48
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi...   185   1e-46
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi...   183   4e-46
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...   180   4e-45
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...   177   3e-44

>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score = 1476 bits (3822), Expect = 0.0
 Identities = 724/724 (100%), Positives = 724/724 (100%)

Query: 1   MGDEDWEAEINPHMSSYVPIFEKDRYSGENGDNFNRTPASSSEMDDGPSRRDHFMKSGFA 60
           MGDEDWEAEINPHMSSYVPIFEKDRYSGENGDNFNRTPASSSEMDDGPSRRDHFMKSGFA
Sbjct: 1   MGDEDWEAEINPHMSSYVPIFEKDRYSGENGDNFNRTPASSSEMDDGPSRRDHFMKSGFA 60

Query: 61  SGRNFGNRDAGECNKRDNTSTMGGFGVGKSFGNRGFSNSRFEDGDSSGFWRESSNDCEDN 120
           SGRNFGNRDAGECNKRDNTSTMGGFGVGKSFGNRGFSNSRFEDGDSSGFWRESSNDCEDN
Sbjct: 61  SGRNFGNRDAGECNKRDNTSTMGGFGVGKSFGNRGFSNSRFEDGDSSGFWRESSNDCEDN 120

Query: 121 PTRNRGFSKRGGYRDGNNSEASGPYRRGGRGSFRGCRGGFGLGSPNNDLDPDECMQRTGG 180
           PTRNRGFSKRGGYRDGNNSEASGPYRRGGRGSFRGCRGGFGLGSPNNDLDPDECMQRTGG
Sbjct: 121 PTRNRGFSKRGGYRDGNNSEASGPYRRGGRGSFRGCRGGFGLGSPNNDLDPDECMQRTGG 180

Query: 181 LFGSRRPVLSGTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQ 240
           LFGSRRPVLSGTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQ
Sbjct: 181 LFGSRRPVLSGTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQ 240

Query: 241 GPKVTYIPPPPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLN 300
           GPKVTYIPPPPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLN
Sbjct: 241 GPKVTYIPPPPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLN 300

Query: 301 NNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRF 360
           NNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRF
Sbjct: 301 NNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRF 360

Query: 361 KELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 420
           KELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC
Sbjct: 361 KELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 420

Query: 421 ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 480
           ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF
Sbjct: 421 ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 480

Query: 481 SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGD 540
           SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGD
Sbjct: 481 SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGD 540

Query: 541 ERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVA 600
           ERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVA
Sbjct: 541 ERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVA 600

Query: 601 ARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVL 660
           ARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVL
Sbjct: 601 ARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVL 660

Query: 661 TDAQQDVPAWLEEIAFSTYIPGFSGSTRGNVFASVDTRKGKSTLNTAGFSSSQAPNPVDD 720
           TDAQQDVPAWLEEIAFSTYIPGFSGSTRGNVFASVDTRKGKSTLNTAGFSSSQAPNPVDD
Sbjct: 661 TDAQQDVPAWLEEIAFSTYIPGFSGSTRGNVFASVDTRKGKSTLNTAGFSSSQAPNPVDD 720

Query: 721 ESWD 724
           ESWD
Sbjct: 721 ESWD 724


>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
           [Homo sapiens]
          Length = 724

 Score = 1476 bits (3822), Expect = 0.0
 Identities = 724/724 (100%), Positives = 724/724 (100%)

Query: 1   MGDEDWEAEINPHMSSYVPIFEKDRYSGENGDNFNRTPASSSEMDDGPSRRDHFMKSGFA 60
           MGDEDWEAEINPHMSSYVPIFEKDRYSGENGDNFNRTPASSSEMDDGPSRRDHFMKSGFA
Sbjct: 1   MGDEDWEAEINPHMSSYVPIFEKDRYSGENGDNFNRTPASSSEMDDGPSRRDHFMKSGFA 60

Query: 61  SGRNFGNRDAGECNKRDNTSTMGGFGVGKSFGNRGFSNSRFEDGDSSGFWRESSNDCEDN 120
           SGRNFGNRDAGECNKRDNTSTMGGFGVGKSFGNRGFSNSRFEDGDSSGFWRESSNDCEDN
Sbjct: 61  SGRNFGNRDAGECNKRDNTSTMGGFGVGKSFGNRGFSNSRFEDGDSSGFWRESSNDCEDN 120

Query: 121 PTRNRGFSKRGGYRDGNNSEASGPYRRGGRGSFRGCRGGFGLGSPNNDLDPDECMQRTGG 180
           PTRNRGFSKRGGYRDGNNSEASGPYRRGGRGSFRGCRGGFGLGSPNNDLDPDECMQRTGG
Sbjct: 121 PTRNRGFSKRGGYRDGNNSEASGPYRRGGRGSFRGCRGGFGLGSPNNDLDPDECMQRTGG 180

Query: 181 LFGSRRPVLSGTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQ 240
           LFGSRRPVLSGTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQ
Sbjct: 181 LFGSRRPVLSGTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQ 240

Query: 241 GPKVTYIPPPPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLN 300
           GPKVTYIPPPPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLN
Sbjct: 241 GPKVTYIPPPPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLN 300

Query: 301 NNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRF 360
           NNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRF
Sbjct: 301 NNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRF 360

Query: 361 KELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 420
           KELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC
Sbjct: 361 KELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 420

Query: 421 ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 480
           ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF
Sbjct: 421 ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 480

Query: 481 SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGD 540
           SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGD
Sbjct: 481 SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGD 540

Query: 541 ERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVA 600
           ERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVA
Sbjct: 541 ERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVA 600

Query: 601 ARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVL 660
           ARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVL
Sbjct: 601 ARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVL 660

Query: 661 TDAQQDVPAWLEEIAFSTYIPGFSGSTRGNVFASVDTRKGKSTLNTAGFSSSQAPNPVDD 720
           TDAQQDVPAWLEEIAFSTYIPGFSGSTRGNVFASVDTRKGKSTLNTAGFSSSQAPNPVDD
Sbjct: 661 TDAQQDVPAWLEEIAFSTYIPGFSGSTRGNVFASVDTRKGKSTLNTAGFSSSQAPNPVDD 720

Query: 721 ESWD 724
           ESWD
Sbjct: 721 ESWD 724


>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
           [Homo sapiens]
          Length = 690

 Score = 1383 bits (3580), Expect = 0.0
 Identities = 689/724 (95%), Positives = 690/724 (95%), Gaps = 34/724 (4%)

Query: 1   MGDEDWEAEINPHMSSYVPIFEKDRYSGENGDNFNRTPASSSEMDDGPSRRDHFMKSGFA 60
           MGDEDWEAEINPHMSSYVPIFEKDRYSGENGDNFNRTPASSSEMDDGPSRRDHFMKSGFA
Sbjct: 1   MGDEDWEAEINPHMSSYVPIFEKDRYSGENGDNFNRTPASSSEMDDGPSRRDHFMKSGFA 60

Query: 61  SGRNFGNRDAGECNKRDNTSTMGGFGVGKSFGNRGFSNSRFEDGDSSGFWRESSNDCEDN 120
           SGRNFGNRDAGECNKRDNTSTMGGFGVGKSFGNRGFSNSRFEDGDSSGFWRESSNDCEDN
Sbjct: 61  SGRNFGNRDAGECNKRDNTSTMGGFGVGKSFGNRGFSNSRFEDGDSSGFWRESSNDCEDN 120

Query: 121 PTRNRGFSKRGGYRDGNNSEASGPYRRGGRGSFRGCRGGFGLGSPNNDLDPDECMQRTGG 180
           PTRNRGFSKRG                                  +NDLDPDECMQRTGG
Sbjct: 121 PTRNRGFSKRG----------------------------------DNDLDPDECMQRTGG 146

Query: 181 LFGSRRPVLSGTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQ 240
           LFGSRRPVLSGTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQ
Sbjct: 147 LFGSRRPVLSGTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQ 206

Query: 241 GPKVTYIPPPPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLN 300
           GPKVTYIPPPPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLN
Sbjct: 207 GPKVTYIPPPPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLN 266

Query: 301 NNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRF 360
           NNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRF
Sbjct: 267 NNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRF 326

Query: 361 KELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 420
           KELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC
Sbjct: 327 KELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 386

Query: 421 ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 480
           ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF
Sbjct: 387 ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 446

Query: 481 SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGD 540
           SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGD
Sbjct: 447 SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGD 506

Query: 541 ERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVA 600
           ERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVA
Sbjct: 507 ERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVA 566

Query: 601 ARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVL 660
           ARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVL
Sbjct: 567 ARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVL 626

Query: 661 TDAQQDVPAWLEEIAFSTYIPGFSGSTRGNVFASVDTRKGKSTLNTAGFSSSQAPNPVDD 720
           TDAQQDVPAWLEEIAFSTYIPGFSGSTRGNVFASVDTRKGKSTLNTAGFSSSQAPNPVDD
Sbjct: 627 TDAQQDVPAWLEEIAFSTYIPGFSGSTRGNVFASVDTRKGKSTLNTAGFSSSQAPNPVDD 686

Query: 721 ESWD 724
           ESWD
Sbjct: 687 ESWD 690


>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
           sapiens]
          Length = 662

 Score =  448 bits (1153), Expect = e-126
 Identities = 265/560 (47%), Positives = 356/560 (63%), Gaps = 40/560 (7%)

Query: 182 FGSRRPVLSGTGNGDTSQSRSGSGSE-------RGGYKGLNEEVITGSGKNSWKSEAEGG 234
           FGSR    S +    +  S  GSGS        R  Y G+      G      K E  G 
Sbjct: 72  FGSR----SDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSR---GDRSGFGKFERGGN 124

Query: 235 ESSDTQGPKVTYIPPPPPED--EDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEE 292
                +  +  +  P PP +  E  +F+   TGINF+KYD I VE +G++ PP I +F +
Sbjct: 125 SRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSD 184

Query: 293 ANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMH 352
             + + +  NI    YT+ TPVQK++IPII   RDLMACAQTGSGKTAAFLLPIL+ +  
Sbjct: 185 VEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYS 244

Query: 353 DGITAS--------RF-KELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGT 403
           DG   +        R+ +  Q P  +++APTREL  QIY EARKFS+ + VR  V+YGG 
Sbjct: 245 DGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGA 304

Query: 404 QLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKL 463
            +G  IR + +GC++L ATPGRL+D++ + KIGL   KYLVLDEADRMLDMGF P+++++
Sbjct: 305 DIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRI 364

Query: 464 ISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVG 523
           +    MP K  R T+MFSATFP+EIQ LA +FL   Y+F+AVG+VG    ++ Q V+ V 
Sbjct: 365 VEQDTMPPKGVRHTMMFSATFPKEIQMLARDFL-DEYIFLAVGRVGSTSENITQKVVWVE 423

Query: 524 QFSKREKLVEILRNIG-DERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQA 582
           +  KR  L+++L   G D  T+VFVETKK AD +  FL  E  + TSIHGDR QR+RE+A
Sbjct: 424 ESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEA 483

Query: 583 LGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAIS 642
           L  FR GK P+LVAT+VAARGLDI NV+HVINFDLPS I+EYVHRIGRTGR GN G A S
Sbjct: 484 LHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATS 543

Query: 643 FFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIAFSTYIPGFSGSTRGNV--------FAS 694
           FF+ E + ++ + L+ +L +A+Q+VP+WLE +A+  +   + GS+RG          F +
Sbjct: 544 FFN-ERNINITKDLLDLLVEAKQEVPSWLENMAYEHH---YKGSSRGRSKSSRFSGGFGA 599

Query: 695 VDTRKGKSTLNTAGFSSSQA 714
            D R+  S  +++ FSSS+A
Sbjct: 600 RDYRQ-SSGASSSSFSSSRA 618


>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  446 bits (1147), Expect = e-125
 Identities = 258/539 (47%), Positives = 347/539 (64%), Gaps = 33/539 (6%)

Query: 200 SRSGSGSE-------RGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQGPKVTYIPPPPP 252
           S  GSGS        R  Y G+      G G+     E  G      +  +  +  P PP
Sbjct: 85  SERGSGSRGRFDDRGRSDYDGIGNRERPGFGR----FERSGHSRWCDKSVEDDWSKPLPP 140

Query: 253 ED--EDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTK 310
            +  E  +F+   TGINF+KYD I VE +G + PP I  F + ++ + +  NI    YT+
Sbjct: 141 SERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTR 200

Query: 311 LTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQE----- 365
            TPVQK++IPII   RDLMACAQTGSGKTAAFLLPIL+ +  DG      K ++E     
Sbjct: 201 PTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDG-PGEALKAVKENGRYG 259

Query: 366 -----PECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 420
                P  +++APTREL  QIY EARKFS+ + VR  V+YGG  +G  IR + +GC++L 
Sbjct: 260 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 319

Query: 421 ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 480
           ATPGRL+D++ + KIGL   KYLVLDEADRMLDMGF P++++++    MP K  R T+MF
Sbjct: 320 ATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMF 379

Query: 481 SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIG- 539
           SATFP+EIQ LA +FL   Y+F+AVG+VG    ++ Q V+ V    KR  L++IL   G 
Sbjct: 380 SATFPKEIQMLARDFL-DEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGS 438

Query: 540 DERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSV 599
           D  T+VFVETKK AD +  FL  E  + TSIHGDR QR+RE+AL  FR GK P+LVAT+V
Sbjct: 439 DSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV 498

Query: 600 AARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKV 659
           AARGLDI NV+HVINFDLPS I+EYVHRIGRTGR GN G A SFF+ E + ++ + L+ +
Sbjct: 499 AARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN-EKNMNITKDLLDL 557

Query: 660 LTDAQQDVPAWLEEIAFSTYIPGFS-GSTRGNVFA----SVDTRKGKSTLNTAGFSSSQ 713
           L +A+Q+VP+WLE +A+  +  G S G ++ N F+    + D R+   + +++GF +S+
Sbjct: 558 LVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYRQSSGS-SSSGFGASR 615



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 10/68 (14%)

Query: 52  DHFMKSGFASGRNFGNRDAGECNKRDNTSTMG----GFGVGKSFGNR----GFSNSR-FE 102
           +H  K G + GR+  NR +G    RD   + G    GFG  +   +R    G+ NSR F 
Sbjct: 575 EHHYKGG-SRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFG 633

Query: 103 DGDSSGFW 110
            G   GF+
Sbjct: 634 GGGYGGFY 641



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 4/68 (5%)

Query: 92  GNRGFSNS-RFEDGDSSGFWRESSNDCEDNPTRNRGFSKRGGYRDGNNSEASGPYRRGGR 150
           G+RG S S RF  G  +  +R+SS         +RG S R G     NS   G    GG 
Sbjct: 581 GSRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFG---GGGY 637

Query: 151 GSFRGCRG 158
           G F    G
Sbjct: 638 GGFYNSDG 645


>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  446 bits (1147), Expect = e-125
 Identities = 258/539 (47%), Positives = 347/539 (64%), Gaps = 33/539 (6%)

Query: 200 SRSGSGSE-------RGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQGPKVTYIPPPPP 252
           S  GSGS        R  Y G+      G G+     E  G      +  +  +  P PP
Sbjct: 85  SERGSGSRGRFDDRGRSDYDGIGNRERPGFGR----FERSGHSRWCDKSVEDDWSKPLPP 140

Query: 253 ED--EDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTK 310
            +  E  +F+   TGINF+KYD I VE +G + PP I  F + ++ + +  NI    YT+
Sbjct: 141 SERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTR 200

Query: 311 LTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQE----- 365
            TPVQK++IPII   RDLMACAQTGSGKTAAFLLPIL+ +  DG      K ++E     
Sbjct: 201 PTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDG-PGEALKAVKENGRYG 259

Query: 366 -----PECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 420
                P  +++APTREL  QIY EARKFS+ + VR  V+YGG  +G  IR + +GC++L 
Sbjct: 260 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 319

Query: 421 ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 480
           ATPGRL+D++ + KIGL   KYLVLDEADRMLDMGF P++++++    MP K  R T+MF
Sbjct: 320 ATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMF 379

Query: 481 SATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIG- 539
           SATFP+EIQ LA +FL   Y+F+AVG+VG    ++ Q V+ V    KR  L++IL   G 
Sbjct: 380 SATFPKEIQMLARDFL-DEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGS 438

Query: 540 DERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSV 599
           D  T+VFVETKK AD +  FL  E  + TSIHGDR QR+RE+AL  FR GK P+LVAT+V
Sbjct: 439 DSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV 498

Query: 600 AARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKV 659
           AARGLDI NV+HVINFDLPS I+EYVHRIGRTGR GN G A SFF+ E + ++ + L+ +
Sbjct: 499 AARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN-EKNMNITKDLLDL 557

Query: 660 LTDAQQDVPAWLEEIAFSTYIPGFS-GSTRGNVFA----SVDTRKGKSTLNTAGFSSSQ 713
           L +A+Q+VP+WLE +A+  +  G S G ++ N F+    + D R+   + +++GF +S+
Sbjct: 558 LVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYRQSSGS-SSSGFGASR 615



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 10/68 (14%)

Query: 52  DHFMKSGFASGRNFGNRDAGECNKRDNTSTMG----GFGVGKSFGNR----GFSNSR-FE 102
           +H  K G + GR+  NR +G    RD   + G    GFG  +   +R    G+ NSR F 
Sbjct: 575 EHHYKGG-SRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFG 633

Query: 103 DGDSSGFW 110
            G   GF+
Sbjct: 634 GGGYGGFY 641



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 4/68 (5%)

Query: 92  GNRGFSNS-RFEDGDSSGFWRESSNDCEDNPTRNRGFSKRGGYRDGNNSEASGPYRRGGR 150
           G+RG S S RF  G  +  +R+SS         +RG S R G     NS   G    GG 
Sbjct: 581 GSRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFG---GGGY 637

Query: 151 GSFRGCRG 158
           G F    G
Sbjct: 638 GGFYNSDG 645


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score =  291 bits (746), Expect = 1e-78
 Identities = 171/455 (37%), Positives = 267/455 (58%), Gaps = 27/455 (5%)

Query: 276 VEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTG 335
           + V GH+ P  +L F EAN    + + IA+  +T+ T +Q    P+ L+G D++  AQTG
Sbjct: 82  ITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTG 141

Query: 336 SGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVR 395
           SGKT ++LLP + H+ H        +    P C+++APTREL  Q+   A ++     ++
Sbjct: 142 SGKTLSYLLPAIVHINHQPF----LERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLK 197

Query: 396 AVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMG 455
           +  IYGG   G  IR + +G  I  ATPGRL+D +   K  L++  YLVLDEADRMLDMG
Sbjct: 198 STCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMG 257

Query: 456 FGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRD 514
           F P+++K++       +  RQTLM+SAT+P+E+++LA +FLK +Y+ + +G +   A  +
Sbjct: 258 FEPQIRKIVD----QIRPDRQTLMWSATWPKEVRQLAEDFLK-DYIHINIGALELSANHN 312

Query: 515 VQQTVLQVGQFSKREKLVEILRNIGDER---TMVFVETKKKADFIATFLCQEKISTTSIH 571
           + Q V       K EKL+ ++  I  E+   T+VFVETK++ D +   + ++      IH
Sbjct: 313 ILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIH 372

Query: 572 GDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRT 631
           GD+ Q+ER+  L +F+ GK P+L+AT VA+RGLD+E+V+ VIN+D P++ ++Y+HRIGRT
Sbjct: 373 GDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRT 432

Query: 632 GRCGNTGRAISFFDLESDNHLAQ--PLVKVLTDAQQDVPAWLEEIAFSTYIPGFSGSTRG 689
            R   TG A +FF   + N++ Q   L+ VL +A Q +   L ++         SG +RG
Sbjct: 433 ARSTKTGTAYTFF---TPNNIKQVSDLISVLREANQAINPKLLQLVEDR----GSGRSRG 485

Query: 690 NVFASVDTRKGKSTLNTAGFSSSQAPNPVDDESWD 724
                 D R   S     GF++ +     D E++D
Sbjct: 486 RGGMKDDRRDRYSAGKRGGFNTFR-----DRENYD 515


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score =  283 bits (725), Expect = 3e-76
 Identities = 180/491 (36%), Positives = 277/491 (56%), Gaps = 28/491 (5%)

Query: 182 FGSRRPVLSGTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQG 241
           FG+ R    G G+ D  + R G G+  GG  GL  +     G+   K + +  E    + 
Sbjct: 77  FGTMRG--GGFGDRDRDRDRGGFGARGGG--GLPPKKFGNPGERLRKKKWDLSELPKFE- 131

Query: 242 PKVTYIPPPPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDA-PPAILTFEEANLCQTLN 300
            K  Y+  P    E +    Y+      K +   + V G D  P  +  F  AN  Q + 
Sbjct: 132 -KNFYVEHP----EVARLTPYEVDELRRKKE---ITVRGGDVCPKPVFAFHHANFPQYVM 183

Query: 301 NNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRF 360
           + +    +T+ TP+Q    P+ L+GRD++  AQTGSGKT A+LLP + H+ H        
Sbjct: 184 DVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPY----L 239

Query: 361 KELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 420
           +    P C+++APTREL  Q+   A  +   + +++  IYGG   G  IR + +G  I  
Sbjct: 240 ERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICI 299

Query: 421 ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 480
           ATPGRL+D +   K  L++  YLVLDEADRMLDMGF P+++K++       +  RQTLM+
Sbjct: 300 ATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVD----QIRPDRQTLMW 355

Query: 481 SATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRDVQQTVLQVGQFSKREKLVEILRNIG 539
           SAT+P+E+++LA +FL+ +Y  + VG +   A  ++ Q V    +  K  KL++++  I 
Sbjct: 356 SATWPKEVRQLAEDFLR-DYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIM 414

Query: 540 DER---TMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVA 596
            E+   T++FVETK++ D +   + ++      IHGD+ Q ER+  L +FR GK P+L+A
Sbjct: 415 AEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIA 474

Query: 597 TSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPL 656
           T VA+RGLD+E+V+ VIN+D P++ ++YVHRIGRT R  N G A +FF    +   A+ L
Sbjct: 475 TDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFF-TPGNLKQAREL 533

Query: 657 VKVLTDAQQDV 667
           +KVL +A Q +
Sbjct: 534 IKVLEEANQAI 544


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score =  283 bits (725), Expect = 3e-76
 Identities = 180/491 (36%), Positives = 277/491 (56%), Gaps = 28/491 (5%)

Query: 182 FGSRRPVLSGTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQG 241
           FG+ R    G G+ D  + R G G+  GG  GL  +     G+   K + +  E    + 
Sbjct: 77  FGTMRG--GGFGDRDRDRDRGGFGARGGG--GLPPKKFGNPGERLRKKKWDLSELPKFE- 131

Query: 242 PKVTYIPPPPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDA-PPAILTFEEANLCQTLN 300
            K  Y+  P    E +    Y+      K +   + V G D  P  +  F  AN  Q + 
Sbjct: 132 -KNFYVEHP----EVARLTPYEVDELRRKKE---ITVRGGDVCPKPVFAFHHANFPQYVM 183

Query: 301 NNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRF 360
           + +    +T+ TP+Q    P+ L+GRD++  AQTGSGKT A+LLP + H+ H        
Sbjct: 184 DVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPY----L 239

Query: 361 KELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 420
           +    P C+++APTREL  Q+   A  +   + +++  IYGG   G  IR + +G  I  
Sbjct: 240 ERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICI 299

Query: 421 ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 480
           ATPGRL+D +   K  L++  YLVLDEADRMLDMGF P+++K++       +  RQTLM+
Sbjct: 300 ATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVD----QIRPDRQTLMW 355

Query: 481 SATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRDVQQTVLQVGQFSKREKLVEILRNIG 539
           SAT+P+E+++LA +FL+ +Y  + VG +   A  ++ Q V    +  K  KL++++  I 
Sbjct: 356 SATWPKEVRQLAEDFLR-DYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIM 414

Query: 540 DER---TMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVA 596
            E+   T++FVETK++ D +   + ++      IHGD+ Q ER+  L +FR GK P+L+A
Sbjct: 415 AEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIA 474

Query: 597 TSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPL 656
           T VA+RGLD+E+V+ VIN+D P++ ++YVHRIGRT R  N G A +FF    +   A+ L
Sbjct: 475 TDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFF-TPGNLKQAREL 533

Query: 657 VKVLTDAQQDV 667
           +KVL +A Q +
Sbjct: 534 IKVLEEANQAI 544


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score =  273 bits (698), Expect = 4e-73
 Identities = 160/395 (40%), Positives = 238/395 (60%), Gaps = 13/395 (3%)

Query: 284 PPAILTFEEANLCQT-LNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAF 342
           P    TF++A  C   +  NI KAG+ K TP+Q  + PI+L G DL+  AQTG+GKT  +
Sbjct: 237 PNPTCTFDDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCY 296

Query: 343 LLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGG 402
           L+P   H++   +  S   +   P  +++ PTREL  Q+  E  K+S+   +R+V +YGG
Sbjct: 297 LMPGFIHLV---LQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYKG-LRSVCVYGG 352

Query: 403 TQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKK 462
                 I ++ +G +I+ ATPGRL D+     + LK I YLVLDEAD+MLDMGF P++ K
Sbjct: 353 GNRDEQIEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMK 412

Query: 463 LISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRDVQQTVLQ 521
           ++    +  +  RQT+M SAT+P  + RLA  +LK   + V VG +   A   V+Q ++ 
Sbjct: 413 IL----LDVRPDRQTVMTSATWPHSVHRLAQSYLKEP-MIVYVGTLDLVAVSSVKQNIIV 467

Query: 522 VGQFSKREKLVEILRNIGD-ERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQRERE 580
             +  K   +   L+++   ++ +VFV  K  AD +++ L    IS  S+HGDREQR+RE
Sbjct: 468 TTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDRE 527

Query: 581 QALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRA 640
           +AL +F+ GK  +L+AT +A+RGLD+ +V HV NFD P  I+EYVHRIGRTGR G TG +
Sbjct: 528 KALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVS 587

Query: 641 ISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIA 675
           I+     +D  +A  L+ +L  A Q +P  L  +A
Sbjct: 588 ITTL-TRNDWRVASELINILERANQSIPEELVSMA 621


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  271 bits (692), Expect = 2e-72
 Identities = 156/416 (37%), Positives = 243/416 (58%), Gaps = 14/416 (3%)

Query: 263 QTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPII 322
           Q  +N  + +   + V G   P  I ++ +  +   + N++ K GY K TP+Q  +IP I
Sbjct: 347 QEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAI 406

Query: 323 LAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIY 382
           ++GRDL+  A+TGSGKT AFLLP+  H+M         +E + P  +I+ PTREL  QI 
Sbjct: 407 MSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQ----RSLEEGEGPIAVIMTPTRELALQIT 462

Query: 383 LEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEK---IGLKQ 439
            E +KFS    +R V +YGGT +   I ++ +G  I+  TPGR++D++         L++
Sbjct: 463 KECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRR 522

Query: 440 IKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSN 499
           + Y+VLDEADRM DMGF P++ +++       +  RQT+MFSATFP  ++ LA   L S 
Sbjct: 523 VTYVVLDEADRMFDMGFEPQVMRIVD----NVRPDRQTVMFSATFPRAMEALARRIL-SK 577

Query: 500 YLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGDERTMV-FVETKKKADFIAT 558
            + V VG     C DV+Q V+ + +  K  KL+E+L +  +  +++ FV+ ++ AD +  
Sbjct: 578 PIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLK 637

Query: 559 FLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLP 618
            L +      S+HG  +Q +R+  + DF+ G C +LVATSVAARGLD++++  V+N+  P
Sbjct: 638 DLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCP 697

Query: 619 STIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEI 674
           +  ++YVHR GRTGR GN G A +F   E     A  ++K L  +   VP  LE++
Sbjct: 698 NHYEDYVHRAGRTGRAGNKGYAYTFI-TEDQARYAGDIIKALELSGTAVPPDLEKL 752


>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
          Length = 622

 Score =  256 bits (653), Expect = 7e-68
 Identities = 154/401 (38%), Positives = 221/401 (55%), Gaps = 13/401 (3%)

Query: 278 VSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSG 337
           V G   PP I +F+E      +   + K G    TP+Q   IP IL+GRD++  A TGSG
Sbjct: 171 VEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSG 230

Query: 338 KTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQI------YLEARKFSFG 391
           KT  F LP++   +        F + + P  +I+ P+REL  Q       Y    +    
Sbjct: 231 KTLVFTLPVIMFCLEQEKRLP-FSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSS 289

Query: 392 TCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRM 451
             +R  +  GG  +   +  I  G +++ ATPGRLMD++ K+ + L   +YL LDEADRM
Sbjct: 290 PLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRM 349

Query: 452 LDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGA 511
           +DMGF  +++ + S      K QRQTL+FSAT P++IQ  A   L    + + VG+ G A
Sbjct: 350 IDMGFEGDIRTIFSY----FKGQRQTLLFSATMPKKIQNFAKSALVKP-VTINVGRAGAA 404

Query: 512 CRDVQQTVLQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIH 571
             DV Q V  V + +K   L+E L+       ++F E K   D I  +L  + +   +IH
Sbjct: 405 SLDVIQEVEYVKEEAKMVYLLECLQKTPPP-VLIFAEKKADVDAIHEYLLLKGVEAVAIH 463

Query: 572 GDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRT 631
           G ++Q ER +A+  FR GK  VLVAT VA++GLD   +QHVIN+D+P  I+ YVHRIGRT
Sbjct: 464 GGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRT 523

Query: 632 GRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLE 672
           GR GNTG A +F +   D  +   L  +L +A+Q VP  L+
Sbjct: 524 GRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQ 564


>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  252 bits (644), Expect = 7e-67
 Identities = 156/405 (38%), Positives = 229/405 (56%), Gaps = 18/405 (4%)

Query: 276 VEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTG 335
           + VSG   P    +F      + L + I K+ YT+ TP+Q   +P+ L+GRD++  A+TG
Sbjct: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300

Query: 336 SGKTAAFLLPILAHMMHDGITASRFKELQE---PECIIVAPTRELVNQIYLEARKFSFGT 392
           SGKTAAF+ P+L H+M         KEL+    P  +IV PTREL  QI+ E ++F    
Sbjct: 301 SGKTAAFIWPMLIHIMDQ-------KELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAY 353

Query: 393 CVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRML 452
            +R+V +YGG  +    + + +G  I+  TPGRL+D + K+   L+++ YLV DEADRM 
Sbjct: 354 NLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMF 413

Query: 453 DMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGAC 512
           DMGF  +++ + S      +  RQTL+FSATF ++I++LA + L  + + V  G +G A 
Sbjct: 414 DMGFEYQVRSIAS----HVRPDRQTLLFSATFRKKIEKLARDIL-IDPIRVVQGDIGEAN 468

Query: 513 RDVQQTV--LQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSI 570
            DV Q V  L  G          ++        ++FV  K  A+ +A  L QE  +   +
Sbjct: 469 EDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLL 528

Query: 571 HGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGR 630
           HGD +Q ER + + DF+    PVLVAT VAARGLDI +++ VIN+D+   ID + HRIGR
Sbjct: 529 HGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGR 588

Query: 631 TGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIA 675
           TGR G  G A +      D++ A  LV+ L  A Q V   L ++A
Sbjct: 589 TGRAGEKGVAYTLL-TPKDSNFAGDLVRNLEGANQHVSKELLDLA 632


>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  252 bits (644), Expect = 7e-67
 Identities = 156/405 (38%), Positives = 229/405 (56%), Gaps = 18/405 (4%)

Query: 276 VEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTG 335
           + VSG   P    +F      + L + I K+ YT+ TP+Q   +P+ L+GRD++  A+TG
Sbjct: 241 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 300

Query: 336 SGKTAAFLLPILAHMMHDGITASRFKELQE---PECIIVAPTRELVNQIYLEARKFSFGT 392
           SGKTAAF+ P+L H+M         KEL+    P  +IV PTREL  QI+ E ++F    
Sbjct: 301 SGKTAAFIWPMLIHIMDQ-------KELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAY 353

Query: 393 CVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRML 452
            +R+V +YGG  +    + + +G  I+  TPGRL+D + K+   L+++ YLV DEADRM 
Sbjct: 354 NLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMF 413

Query: 453 DMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGAC 512
           DMGF  +++ + S      +  RQTL+FSATF ++I++LA + L  + + V  G +G A 
Sbjct: 414 DMGFEYQVRSIAS----HVRPDRQTLLFSATFRKKIEKLARDIL-IDPIRVVQGDIGEAN 468

Query: 513 RDVQQTV--LQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSI 570
            DV Q V  L  G          ++        ++FV  K  A+ +A  L QE  +   +
Sbjct: 469 EDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLL 528

Query: 571 HGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGR 630
           HGD +Q ER + + DF+    PVLVAT VAARGLDI +++ VIN+D+   ID + HRIGR
Sbjct: 529 HGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGR 588

Query: 631 TGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIA 675
           TGR G  G A +      D++ A  LV+ L  A Q V   L ++A
Sbjct: 589 TGRAGEKGVAYTLL-TPKDSNFAGDLVRNLEGANQHVSKELLDLA 632


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score =  250 bits (638), Expect = 4e-66
 Identities = 149/400 (37%), Positives = 224/400 (56%), Gaps = 35/400 (8%)

Query: 276 VEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTG 335
           +   G   P  I ++++++L   +   I K GY + TP+Q+ +IPI L  RD++  A+TG
Sbjct: 379 ITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETG 438

Query: 336 SGKTAAFLLPILAHMMHDGITASRFKELQE----PECIIVAPTRELVNQIYLEARKFSFG 391
           SGKTAAFL+P+L  +     T  +   ++E    P  II+APTREL  QI  E  KF   
Sbjct: 439 SGKTAAFLIPLLVWIT----TLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKP 494

Query: 392 TCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRM 451
             +R V + GG        ++  GC I+ ATPGRL+D++    + L +  Y+VLDEADRM
Sbjct: 495 LGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRM 554

Query: 452 LDMGFGPEMKKLISCPGMPSKEQ------------------------RQTLMFSATFPEE 487
           +DMGF P+++K++    MP   Q                        RQT+MF+AT P  
Sbjct: 555 IDMGFEPDVQKILE--HMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPA 612

Query: 488 IQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGDERTMVFV 547
           ++RLA  +L+   + V +G  G     V+Q V  + +  KR+KL+ IL    D   ++FV
Sbjct: 613 VERLARSYLRRPAV-VYIGSAGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFV 671

Query: 548 ETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIE 607
             KK  D +A  L +   +  ++HG + Q +RE AL + + G   +LVAT VA RG+DI+
Sbjct: 672 NQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQ 731

Query: 608 NVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLE 647
           +V  V+N+D+   I++Y+HRIGRTGR G +G AI+F   E
Sbjct: 732 DVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKE 771


>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
           sapiens]
          Length = 631

 Score =  244 bits (624), Expect = 2e-64
 Identities = 139/372 (37%), Positives = 223/372 (59%), Gaps = 12/372 (3%)

Query: 299 LNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITAS 358
           L  +I + G  K TP+Q  + PIIL G DL+  AQTG+GKT ++L+P   H+  D    S
Sbjct: 233 LLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHL--DSQPIS 290

Query: 359 RFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNI 418
           R ++   P  +++ PTREL   +  E  K+S+   ++++ IYGG      I  I +G +I
Sbjct: 291 R-EQRNGPGMLVLTPTRELALHVEAECSKYSYKG-LKSICIYGGRNRNGQIEDISKGVDI 348

Query: 419 LCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTL 478
           + ATPGRL D+     + L+ I YLV+DEAD+MLDM F P+++K++    +  +  RQT+
Sbjct: 349 IIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKIL----LDVRPDRQTV 404

Query: 479 MFSATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRDVQQTVLQVGQFSKREKLVEILRN 537
           M SAT+P+ +++LA  +LK   + V VG +   A   V+Q ++   +  KR    E + N
Sbjct: 405 MTSATWPDTVRQLALSYLKDP-MIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVEN 463

Query: 538 IG-DERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVA 596
           +  +++ ++FV  K  AD +++    + IS  S+HG+ EQ ++E+A+ DF+ G   +L+ 
Sbjct: 464 MSPNDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILIT 523

Query: 597 TSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPL 656
           T + +RGLD+ +V HV N+D P  ID YVHR+G  GR G TG +++    + D+ +A  L
Sbjct: 524 TDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLI-TQRDSKMAGEL 582

Query: 657 VKVLTDAQQDVP 668
           +K+L  A Q VP
Sbjct: 583 IKILDRANQSVP 594


>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score =  238 bits (606), Expect = 2e-62
 Identities = 150/427 (35%), Positives = 241/427 (56%), Gaps = 24/427 (5%)

Query: 232 EGGESSDTQGPKVTYIPPPPPEDEDSIFAHYQTGINF--DKYDTILVE----VSGHDAPP 285
           E  E S    P+     P  P +   ++  +   +N   D+ + +  +    V G +   
Sbjct: 141 EKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTR 200

Query: 286 AILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLP 345
            I+ FE  +L + LN+N+ K+GY   TP+Q   IP+ L GRD++A A TGSGKTAAFLLP
Sbjct: 201 PIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLP 260

Query: 346 ILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTC-VRAVVIYGGTQ 404
           ++   + +  T         P  +I+ PTREL  QI  +A++   G   ++ V++ GG  
Sbjct: 261 VIMRALFESKT---------PSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLP 311

Query: 405 LGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLI 464
           L   + ++ Q   ++ ATPGRL+DII +  + L  +K +V+DEAD ML MGF  ++  ++
Sbjct: 312 LPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDIL 371

Query: 465 SCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQ 524
               +P+    QT++ SAT P  I++LA++ L  N + +  G+    C +V+Q +L V  
Sbjct: 372 E--NIPN--DCQTILVSATIPTSIEQLASQLLH-NPVRIITGEKNLPCANVRQIILWVED 426

Query: 525 FSKREKLVEIL--RNIGDERTMVFVETKKKADFIATFLCQ-EKISTTSIHGDREQREREQ 581
            +K++KL EIL  + +     +VFV+ K  AD ++  + +   + + SIH ++ Q ER+ 
Sbjct: 427 PAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKN 486

Query: 582 ALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAI 641
            L     G   V+V+T V  RGLD+ +V+ V+NFD+PS++DEYVH+IGR GR G  G AI
Sbjct: 487 ILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAI 546

Query: 642 SFFDLES 648
           +F +  S
Sbjct: 547 TFINNNS 553


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score =  208 bits (530), Expect = 1e-53
 Identities = 136/377 (36%), Positives = 209/377 (55%), Gaps = 20/377 (5%)

Query: 288 LTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPIL 347
           L+F++ NL + L   I   G+ + TP+QK  IP+ L G+D+ ACA TG+GKTAAF LP+L
Sbjct: 218 LSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVL 277

Query: 348 AHMMHDGITASRFKELQEP--ECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQL 405
             ++        +K  Q P    +++ PTREL  Q++   R+ +    +   +  GG  +
Sbjct: 278 ERLI--------YKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDV 329

Query: 406 GHSIRQIVQGCNILCATPGRLMDIIGK-EKIGLKQIKYLVLDEADRMLDMGFGPEMKKLI 464
                 +    +IL ATPGRL+D +       L  I+ L+LDEADRMLD  F  +MK++I
Sbjct: 330 KSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEII 389

Query: 465 SCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQV-- 522
                     RQT++FSAT  +E++ LA+  LK N + + V         ++Q  +++  
Sbjct: 390 RM----CSHHRQTMLFSATMTDEVKDLASVSLK-NPVRIFVNSNTDVAPFLRQEFIRIRP 444

Query: 523 GQFSKREKLVE-ILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQ 581
            +   RE +V  +L     +  M+F +TKK+A  +   L    +    +HG+  Q +R +
Sbjct: 445 NREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLE 504

Query: 582 ALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAI 641
           AL  F+  +  +LVAT VAARGLDIE V+ VINF +P+TI  YVHR+GRT R G  GR++
Sbjct: 505 ALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSV 564

Query: 642 SFFDLESDNHLAQPLVK 658
           S    E +  + + +VK
Sbjct: 565 SLVG-EDERKMLKEIVK 580


>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
           sapiens]
          Length = 599

 Score =  207 bits (527), Expect = 3e-53
 Identities = 167/557 (29%), Positives = 274/557 (49%), Gaps = 49/557 (8%)

Query: 145 YRRGGRGS------FRGCRGGFGLGSPNNDLDPDECMQRTGGLFGSRRPVLSGTGNGDTS 198
           +RR G G+      F      F +G    D D  E +Q     FG+++ V    G   T 
Sbjct: 7   FRRLGAGAKFDTRRFSADAARFQIGKRKYDFDSSEVLQGLD-FFGNKKSVPGVCGASQTH 65

Query: 199 QSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGES---SDTQGPKVTYIPPPPPEDE 255
           Q        + G K   EE +T   +   K + +   S   S  +G  + ++     + E
Sbjct: 66  QK------PQNGEK--KEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIE 117

Query: 256 DSIFAHYQTGINFDKYDTILVE------------VSGHDAPPAILTFEEANLCQTLNN-- 301
           D      ++ +   K + +  E            V G D P  I TF++ +    +N+  
Sbjct: 118 DKKVQR-ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRL 176

Query: 302 --NIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASR 359
             NI  AG+   TP+Q  +IP++L GR+L+A A TGSGKT AF +PIL  +        R
Sbjct: 177 LQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFR 236

Query: 360 FKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIR-QIVQGCNI 418
                    +I++PTREL +QI+ E  K S GT  R  +I+           +  +  +I
Sbjct: 237 --------ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 288

Query: 419 LCATPGRLMDIIGKEKIG--LKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQ 476
           L  TP RL+ ++ ++  G  L  +++LV+DE+D++ + G      +L S     +  + +
Sbjct: 289 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 348

Query: 477 TLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVG-QFSKREKLVEIL 535
             MFSATF  ++++     L  N + V++G    A   V+Q +L VG +  K   + E++
Sbjct: 349 RAMFSATFAYDVEQWCKLNL-DNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELV 407

Query: 536 RNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLV 595
           +   +   +VFV++ ++A  +   L  E I+   IH +R Q++R+  +  FR GK  VL+
Sbjct: 408 KKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLI 467

Query: 596 ATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQP 655
            T++ ARG+D + V  VIN+D P++  EY+HRIGRTGR GN G+AI+FF  E D  L + 
Sbjct: 468 CTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFF-TEDDKPLLRS 526

Query: 656 LVKVLTDAQQDVPAWLE 672
           +  V+  A   VP +++
Sbjct: 527 VANVIQQAGCPVPEYIK 543


>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
           sapiens]
          Length = 491

 Score =  206 bits (523), Expect = 8e-53
 Identities = 137/405 (33%), Positives = 223/405 (55%), Gaps = 18/405 (4%)

Query: 276 VEVSGHDAPPAILTFEEANLCQTLNN----NIAKAGYTKLTPVQKYSIPIILAGRDLMAC 331
           + V G D P  I TF++ +    +N+    NI  AG+   TP+Q  +IP++L GR+L+A 
Sbjct: 41  IHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLAS 100

Query: 332 AQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFG 391
           A TGSGKT AF +PIL  +        R         +I++PTREL +QI+ E  K S G
Sbjct: 101 APTGSGKTLAFSIPILMQLKQPANKGFR--------ALIISPTRELASQIHRELIKISEG 152

Query: 392 TCVRAVVIYGGTQLGHSIR-QIVQGCNILCATPGRLMDIIGKEKIG--LKQIKYLVLDEA 448
           T  R  +I+           +  +  +IL  TP RL+ ++ ++  G  L  +++LV+DE+
Sbjct: 153 TGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDES 212

Query: 449 DRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQV 508
           D++ + G      +L S     +  + +  MFSATF  ++++     L  N + V++G  
Sbjct: 213 DKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNL-DNVISVSIGAR 271

Query: 509 GGACRDVQQTVLQVG-QFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKIST 567
             A   V+Q +L VG +  K   + E+++   +   +VFV++ ++A  +   L  E I+ 
Sbjct: 272 NSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINV 331

Query: 568 TSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHR 627
             IH +R Q++R+  +  FR GK  VL+ T++ ARG+D + V  VIN+D P++  EY+HR
Sbjct: 332 DVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHR 391

Query: 628 IGRTGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLE 672
           IGRTGR GN G+AI+FF  E D  L + +  V+  A   VP +++
Sbjct: 392 IGRTGRAGNKGKAITFF-TEDDKPLLRSVANVIQQAGCPVPEYIK 435


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score =  206 bits (523), Expect = 8e-53
 Identities = 150/452 (33%), Positives = 232/452 (51%), Gaps = 33/452 (7%)

Query: 215 NEEVITGSGKNSWKSEAEGGESSDTQGPKVTY-IPPPPPEDEDSIFAHYQTGINFDKYDT 273
           +EE I        K E E    +  + PK+    P P P+   S  A  ++    ++   
Sbjct: 121 SEEEIDAPKPKKMKKEKEMNGETREKSPKLKNGFPHPEPDCNPSEAASEESNSEIEQ--- 177

Query: 274 ILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQ 333
              E+       A   F    + +     +   G T L P+Q  +   + +G+DL+A A+
Sbjct: 178 ---EIPVEQKEGAFSNFP---ISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQAR 231

Query: 334 TGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTC 393
           TG+GKT +F +P++  +   G    R K  + P+ +++APTREL NQ+   ++ FS  T 
Sbjct: 232 TGTGKTFSFAIPLIEKL--HGELQDR-KRGRAPQVLVLAPTRELANQV---SKDFSDITK 285

Query: 394 VRAVV-IYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRML 452
             +V   YGGT  G    ++  G +IL  TPGR+ D I   K+ L ++K++VLDE D+ML
Sbjct: 286 KLSVACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQML 345

Query: 453 DMGFGPEMKKLISCP-GMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGA 511
           DMGF  ++++++S      S++  QTL+FSAT P  +  +A +++KS Y      QV   
Sbjct: 346 DMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTY-----EQVDLI 400

Query: 512 CRDVQQTVLQVGQFSKREKLVEILRNIGDE---------RTMVFVETKKKADFIATFLCQ 562
            +  Q+T + V   + +    +    IGD          RT++F ETKK+A  ++     
Sbjct: 401 GKKTQKTAITVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAI 460

Query: 563 EKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTID 622
           ++    S+HGD  Q++RE  L  FR G   VLVAT+VAARGLDI  V  VI    P  ++
Sbjct: 461 KQ-DAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVE 519

Query: 623 EYVHRIGRTGRCGNTGRAISFFDLESDNHLAQ 654
            Y+HR GRTGR G TG  I F+  + +  L Q
Sbjct: 520 SYIHRSGRTGRAGRTGVCICFYQHKEEYQLVQ 551


>gi|13129006 nucleolar protein GU2 [Homo sapiens]
          Length = 737

 Score =  196 bits (497), Expect = 8e-50
 Identities = 123/343 (35%), Positives = 194/343 (56%), Gaps = 11/343 (3%)

Query: 307 GYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEP 366
           G T L P+Q  +   +  G+DL+A A+TG+GKT +F +P++  +  +  T    K+ + P
Sbjct: 156 GVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERLQRNQET---IKKSRSP 212

Query: 367 ECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRL 426
           + +++APTREL NQ+  + +  +    V     YGGT     I  I  G +IL  TPGR+
Sbjct: 213 KVLVLAPTRELANQVAKDFKDITRKLSVAC--FYGGTSYQSQINHIRNGIDILVGTPGRI 270

Query: 427 MDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLI-SCPGMPSKEQRQTLMFSATFP 485
            D +   ++ L +++++VLDE D+MLD+GF  +++ +I       S++  QTL+FSAT P
Sbjct: 271 KDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKTDSEDNPQTLLFSATCP 330

Query: 486 EEIQRLAAEFLKSNYLFV-AVGQVGG-ACRDVQQTVLQVGQFSKREKLVEILR--NIGDE 541
           + + ++A +++KS Y  V  VG++   A   V+   +Q     +   + ++L+  +  + 
Sbjct: 331 QWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCHWSQRPAVIGDVLQVYSGSEG 390

Query: 542 RTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAA 601
           R ++F ETKK    +A      K +   +HGD  Q +RE  L  FR G   VLVAT+VAA
Sbjct: 391 RAIIFCETKKNVTEMA-MNPHIKQNAQCLHGDIAQSQREITLKGFREGSFKVLVATNVAA 449

Query: 602 RGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFF 644
           RGLDI  V  VI    P  ++ Y+HR GRTGR G TG  I F+
Sbjct: 450 RGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICFY 492


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score =  192 bits (487), Expect = 1e-48
 Identities = 125/363 (34%), Positives = 190/363 (52%), Gaps = 18/363 (4%)

Query: 289 TFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILA 348
           TF++  +   L     + G+TK T +Q  +IP+ L GRD++  A+TGSGKT AF LPIL 
Sbjct: 25  TFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILN 84

Query: 349 HMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHS 408
            ++            Q    +++ PTREL  QI  +         V++ VI GG      
Sbjct: 85  ALLETP---------QRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQ 135

Query: 409 IRQIVQGCNILCATPGRLMDIIGKEK-IGLKQIKYLVLDEADRMLDMGFGPEMKKLISCP 467
              + +  +I+ ATPGRL+D +   K   L+ +KYLV+DEADR+L+M F  E+ K++   
Sbjct: 136 SLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKV- 194

Query: 468 GMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSK 527
                  R+T +FSAT  +++Q+L    LK N +  AV         +QQ  + +    K
Sbjct: 195 ---IPRDRKTFLFSATMTKKVQKLQRAALK-NPVKCAVSSKYQTVEKLQQYYIFIPSKFK 250

Query: 528 REKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFR 587
              LV IL  +     M+F  T       A  L     +   +HG   Q +R  +L  F+
Sbjct: 251 DTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFK 310

Query: 588 FGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISF---F 644
                +L+AT VA+RGLDI +V  V+NFD+P+   +Y+HR+GRT R G +G+AI+F   +
Sbjct: 311 AKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQY 370

Query: 645 DLE 647
           D+E
Sbjct: 371 DVE 373


>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score =  191 bits (485), Expect = 2e-48
 Identities = 125/404 (30%), Positives = 218/404 (53%), Gaps = 23/404 (5%)

Query: 272 DTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMAC 331
           D   VE    +      TF+   L + L   I   G+ K + +Q+ +I  I+ GRD++A 
Sbjct: 22  DMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQ 81

Query: 332 AQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFG 391
           +Q+G+GKTA F + +L  +           +++E + +I+APTREL  QI          
Sbjct: 82  SQSGTGKTATFSISVLQCLDI---------QVRETQALILAPTRELAVQIQKGLLALGDY 132

Query: 392 TCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRM 451
             V+     GGT +G  IR++  G +++  TPGR+ D+I +  +  + IK LVLDEAD M
Sbjct: 133 MNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEM 192

Query: 452 LDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGA 511
           L+ GF  ++  +     +P   Q   ++ SAT P EI  +  +F+ ++ + + V +    
Sbjct: 193 LNKGFKEQIYDVYRY--LPPATQ--VVLISATLPHEILEMTNKFM-TDPIRILVKRDELT 247

Query: 512 CRDVQQTVLQVGQFS-KREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSI 570
              ++Q  + V +   K + L ++   +   + ++F  TK+K D++   + +   + +S+
Sbjct: 248 LEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSM 307

Query: 571 HGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGR 630
           HGD  Q+ERE  + +FR G   VL++T V ARGLD+  V  +IN+DLP+  + Y+HRIGR
Sbjct: 308 HGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGR 367

Query: 631 TGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEI 674
           +GR G  G AI+F  +++D+      +++L D +Q     ++E+
Sbjct: 368 SGRYGRKGVAINF--VKNDD------IRILRDIEQYYSTQIDEM 403


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score =  191 bits (485), Expect = 2e-48
 Identities = 116/357 (32%), Positives = 195/357 (54%), Gaps = 18/357 (5%)

Query: 290 FEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAH 349
           F+   L   +   I K GY   TP+Q+ +IP+IL G+D++A A+TGSGKTA FLLP+   
Sbjct: 98  FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFER 157

Query: 350 MM-HDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHS 408
           +  H   T +R         +I++PTREL  Q     ++    T ++  +I GG ++   
Sbjct: 158 LKTHSAQTGAR--------ALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQ 209

Query: 409 IRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLIS-CP 467
              + +  +I+ ATPGRL+ +  +  + L+ ++Y+V DEADR+ +MGF  +++++I+  P
Sbjct: 210 FAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLP 269

Query: 468 GMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSK 527
           G       QT++FSAT P+ +   A   L    L + +         ++ +   V + +K
Sbjct: 270 G-----GHQTVLFSATLPKLLVEFARAGLTEPVL-IRLDVDTKLNEQLKTSFFLVREDTK 323

Query: 528 REKLVEILRNI--GDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGD 585
              L+ +L N+    ++T+VFV TK  A+++   L  +++S   I+   +   R+  L  
Sbjct: 324 AAVLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAK 383

Query: 586 FRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAIS 642
           F  GKC  L+ T +AARGLDI  + +VIN+  P+    ++HR+GR  R G +G A S
Sbjct: 384 FTLGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYS 440


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score =  191 bits (485), Expect = 2e-48
 Identities = 116/357 (32%), Positives = 195/357 (54%), Gaps = 18/357 (5%)

Query: 290 FEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAH 349
           F+   L   +   I K GY   TP+Q+ +IP+IL G+D++A A+TGSGKTA FLLP+   
Sbjct: 98  FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFER 157

Query: 350 MM-HDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHS 408
           +  H   T +R         +I++PTREL  Q     ++    T ++  +I GG ++   
Sbjct: 158 LKTHSAQTGAR--------ALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQ 209

Query: 409 IRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLIS-CP 467
              + +  +I+ ATPGRL+ +  +  + L+ ++Y+V DEADR+ +MGF  +++++I+  P
Sbjct: 210 FAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLP 269

Query: 468 GMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSK 527
           G       QT++FSAT P+ +   A   L    L + +         ++ +   V + +K
Sbjct: 270 G-----GHQTVLFSATLPKLLVEFARAGLTEPVL-IRLDVDTKLNEQLKTSFFLVREDTK 323

Query: 528 REKLVEILRNI--GDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGD 585
              L+ +L N+    ++T+VFV TK  A+++   L  +++S   I+   +   R+  L  
Sbjct: 324 AAVLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAK 383

Query: 586 FRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAIS 642
           F  GKC  L+ T +AARGLDI  + +VIN+  P+    ++HR+GR  R G +G A S
Sbjct: 384 FTLGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYS 440


>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
           sapiens]
          Length = 483

 Score =  185 bits (469), Expect = 1e-46
 Identities = 127/377 (33%), Positives = 194/377 (51%), Gaps = 27/377 (7%)

Query: 290 FEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAH 349
           F E  L   L     + G  + TPVQ   IP IL GRD + CA+TGSGKTAAF+LPIL  
Sbjct: 4   FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63

Query: 350 MMHD--GITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGH 407
           +  D  GI            C+++ PTREL  QI  + R       ++  +I GG  +  
Sbjct: 64  LSEDPYGIF-----------CLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVA 112

Query: 408 SIRQIVQGCNILCATPGRLMDII-GKEKIGLKQIKYLVLDEADRMLDMG---FGPEMKKL 463
              ++ +  +++ ATPGRL D +       +K+I++LV+DEADR+L+ G   F  +++ +
Sbjct: 113 QALELSRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAI 172

Query: 464 ISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVG 523
           ++   +P++  RQTL+FSAT  + ++ L        + + A   V      + Q  L V 
Sbjct: 173 LAA--VPAR--RQTLLFSATLTDTLRELQGLATNQPFFWEAQAPVS-TVEQLDQRYLLVP 227

Query: 524 QFSKREKLVEILRNIGDERT----MVFVETKKKADFIATFLCQEKISTTSIHGDREQRER 579
           +  K   LV +++   DE      ++F  T K    +   L +    T ++H   +Q+ER
Sbjct: 228 EKVKDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKER 287

Query: 580 EQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGR 639
             AL  F+     +L+AT VA+RGLDI  VQ VIN + P     Y+HR+GRT R G  G+
Sbjct: 288 FAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQ 347

Query: 640 AISFFDLESDNHLAQPL 656
           AI+    + D HL   +
Sbjct: 348 AITLV-TQYDIHLVHAI 363


>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
           sapiens]
          Length = 483

 Score =  183 bits (465), Expect = 4e-46
 Identities = 119/358 (33%), Positives = 191/358 (53%), Gaps = 24/358 (6%)

Query: 290 FEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAH 349
           FE+  L + L   I + G+ K +P+Q+ SIPI L+GRD++A A+ G+GK+ A+L+P+L  
Sbjct: 98  FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLER 157

Query: 350 M--MHDGITASRFKELQEPECIIVAPTREL---VNQIYLEARKFSFGTCVRAVVIYGGTQ 404
           +    D I A           +++ PTREL   V+QI ++  K   G  V A    GGT 
Sbjct: 158 LDLKKDNIQA-----------MVIVPTRELALQVSQICIQVSKHMGGAKVMATT--GGTN 204

Query: 405 LGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLI 464
           L   I ++    +++ ATPGR++D+I K    +  ++ +VLDEAD++L   F   M+ +I
Sbjct: 205 LRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDII 264

Query: 465 SCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQ 524
               +   + RQ L++SATFP  +Q+     L+  Y    + ++    + V Q    V +
Sbjct: 265 ----LTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEEL--TLKGVTQYYAYVTE 318

Query: 525 FSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALG 584
             K   L  +   +   ++++F  + ++ + +A  + Q   S   IH    Q  R +   
Sbjct: 319 RQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFH 378

Query: 585 DFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAIS 642
           DFR G C  LV T +  RG+DI+ V  VINFD P   + Y+HRIGR+GR G+ G AI+
Sbjct: 379 DFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAIN 436


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score =  180 bits (457), Expect = 4e-45
 Identities = 111/384 (28%), Positives = 205/384 (53%), Gaps = 23/384 (5%)

Query: 290 FEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAH 349
           F++ NL ++L   I   G+ K + +Q+ +I   + G D++A AQ+G+GKTA F + IL  
Sbjct: 35  FDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQ 94

Query: 350 MMHDGITASRFKELQEPECIIVAPTRELVNQIY---LEARKFSFGTCVRAVVIYGGTQLG 406
           +           E +E + +++APTREL  QI    L    +   TC   +   GGT + 
Sbjct: 95  LEI---------EFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACI---GGTNVR 142

Query: 407 HSIRQI-VQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLIS 465
           + ++++  +  +I+  TPGR+ D++ +  +  K IK  VLDEAD ML  GF  ++ ++  
Sbjct: 143 NEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQ 202

Query: 466 CPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQF 525
                     Q ++ SAT P ++  +  +F++   + + V +       ++Q  + V + 
Sbjct: 203 ----KLNTSIQVVLLSATMPTDVLEVTKKFMRDP-IRILVKKEELTLEGIKQFYINVERE 257

Query: 526 S-KREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALG 584
             K + L ++   +   + ++F+ T++K D++   +     + +++HGD +Q+ER+  + 
Sbjct: 258 EWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMR 317

Query: 585 DFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFF 644
           +FR G   VL+ T + ARG+D++ V  VIN+DLP+  + Y+HRIGR GR G  G AI+F 
Sbjct: 318 EFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFV 377

Query: 645 DLESDNHLAQPLVKVLTDAQQDVP 668
             E D  + + +        +++P
Sbjct: 378 -TEEDKRILRDIETFYNTTVEEMP 400


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score =  177 bits (449), Expect = 3e-44
 Identities = 106/366 (28%), Positives = 192/366 (52%), Gaps = 16/366 (4%)

Query: 289 TFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILA 348
           +F++ NL ++L   I   G+ K + +Q+ +I   + G D++A AQ+G+GKTA F + IL 
Sbjct: 33  SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 92

Query: 349 HMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHS 408
            +  D         L+  + +++APTREL  QI                   GGT +   
Sbjct: 93  QIELD---------LKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAE 143

Query: 409 IRQI-VQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCP 467
           ++++ ++  +I+  TPGR+ D++ +  +  K IK  VLDEAD ML  GF  ++  +    
Sbjct: 144 VQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQ-- 201

Query: 468 GMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFS- 526
                   Q ++ SAT P ++  +  +F++   + + V +       ++Q  + V +   
Sbjct: 202 --KLNSNTQVVLLSATMPSDVLEVTKKFMRDP-IRILVKKEELTLEGIRQFYINVEREEW 258

Query: 527 KREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDF 586
           K + L ++   +   + ++F+ T++K D++   +     + +++HGD +Q+ER+  + +F
Sbjct: 259 KLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREF 318

Query: 587 RFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDL 646
           R G   VL+ T + ARG+D++ V  VIN+DLP+  + Y+HRIGR GR G  G AI+    
Sbjct: 319 RSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTE 378

Query: 647 ESDNHL 652
           E    L
Sbjct: 379 EDKRTL 384


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.135    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,038,020
Number of Sequences: 37866
Number of extensions: 1502362
Number of successful extensions: 5901
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 136
Number of HSP's that attempted gapping in prelim test: 4949
Number of HSP's gapped (non-prelim): 628
length of query: 724
length of database: 18,247,518
effective HSP length: 110
effective length of query: 614
effective length of database: 14,082,258
effective search space: 8646506412
effective search space used: 8646506412
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.