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Search of human proteins with 209571582
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|209571582 farnesyl diphosphate synthase isoform a [Homo
sapiens]
(419 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209571582 farnesyl diphosphate synthase isoform a [Homo sapiens] 857 0.0
gi|4503685 farnesyl diphosphate synthase isoform a [Homo sapiens] 857 0.0
gi|209571584 farnesyl diphosphate synthase isoform b [Homo sapiens] 711 0.0
gi|83700220 geranylgeranyl diphosphate synthase 1 isoform A [Hom... 45 2e-04
gi|4758430 geranylgeranyl diphosphate synthase 1 isoform A [Homo... 45 2e-04
gi|83700223 geranylgeranyl diphosphate synthase 1 isoform B [Hom... 43 6e-04
gi|50659086 prenyl diphosphate synthase, subunit 1 [Homo sapiens] 34 0.22
gi|31377562 HAUS augmin-like complex, subunit 6 [Homo sapiens] 32 1.4
gi|38505176 prostaglandin E receptor 3, subtype EP3 isoform 3 [H... 31 1.8
gi|239756261 PREDICTED: similar to hect domain and RLD 2 [Homo s... 30 4.1
gi|239750798 PREDICTED: similar to hect domain and RLD 2 [Homo s... 30 4.1
gi|239745140 PREDICTED: similar to hect domain and RLD 2 [Homo s... 30 4.1
gi|89276764 prostaglandin E receptor 3, subtype EP3 isoform 2 [H... 30 5.3
gi|44681484 cell division cycle associated 2 [Homo sapiens] 29 7.0
>gi|209571582 farnesyl diphosphate synthase isoform a [Homo sapiens]
Length = 419
Score = 857 bits (2213), Expect = 0.0
Identities = 419/419 (100%), Positives = 419/419 (100%)
Query: 1 MPLSRWLRSVGVFLLPAPYWAPRERWLGSLRRPSLVHGYPVLAWHSARCWCQAWTEEPRA 60
MPLSRWLRSVGVFLLPAPYWAPRERWLGSLRRPSLVHGYPVLAWHSARCWCQAWTEEPRA
Sbjct: 1 MPLSRWLRSVGVFLLPAPYWAPRERWLGSLRRPSLVHGYPVLAWHSARCWCQAWTEEPRA 60
Query: 61 LCSSLRMNGDQNSDVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAI 120
LCSSLRMNGDQNSDVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAI
Sbjct: 61 LCSSLRMNGDQNSDVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAI 120
Query: 121 GGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRG 180
GGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRG
Sbjct: 121 GGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRG 180
Query: 181 QICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLD 240
QICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLD
Sbjct: 181 QICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLD 240
Query: 241 LLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLE 300
LLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLE
Sbjct: 241 LLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLE 300
Query: 301 MGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKE 360
MGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKE
Sbjct: 301 MGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKE 360
Query: 361 AEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK 419
AEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Sbjct: 361 AEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK 419
>gi|4503685 farnesyl diphosphate synthase isoform a [Homo sapiens]
Length = 419
Score = 857 bits (2213), Expect = 0.0
Identities = 419/419 (100%), Positives = 419/419 (100%)
Query: 1 MPLSRWLRSVGVFLLPAPYWAPRERWLGSLRRPSLVHGYPVLAWHSARCWCQAWTEEPRA 60
MPLSRWLRSVGVFLLPAPYWAPRERWLGSLRRPSLVHGYPVLAWHSARCWCQAWTEEPRA
Sbjct: 1 MPLSRWLRSVGVFLLPAPYWAPRERWLGSLRRPSLVHGYPVLAWHSARCWCQAWTEEPRA 60
Query: 61 LCSSLRMNGDQNSDVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAI 120
LCSSLRMNGDQNSDVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAI
Sbjct: 61 LCSSLRMNGDQNSDVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAI 120
Query: 121 GGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRG 180
GGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRG
Sbjct: 121 GGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRG 180
Query: 181 QICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLD 240
QICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLD
Sbjct: 181 QICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLD 240
Query: 241 LLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLE 300
LLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLE
Sbjct: 241 LLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLE 300
Query: 301 MGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKE 360
MGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKE
Sbjct: 301 MGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKE 360
Query: 361 AEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK 419
AEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Sbjct: 361 AEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK 419
>gi|209571584 farnesyl diphosphate synthase isoform b [Homo sapiens]
Length = 353
Score = 711 bits (1834), Expect = 0.0
Identities = 353/353 (100%), Positives = 353/353 (100%)
Query: 67 MNGDQNSDVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNR 126
MNGDQNSDVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNR
Sbjct: 1 MNGDQNSDVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNR 60
Query: 127 GLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQ 186
GLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQ
Sbjct: 61 GLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQ 120
Query: 187 KPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQ 246
KPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQ
Sbjct: 121 KPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQ 180
Query: 247 GNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQ 306
GNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQ
Sbjct: 181 GNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQ 240
Query: 307 IQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVAR 366
IQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVAR
Sbjct: 241 IQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVAR 300
Query: 367 VKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK 419
VKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Sbjct: 301 VKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK 353
>gi|83700220 geranylgeranyl diphosphate synthase 1 isoform A [Homo
sapiens]
Length = 300
Score = 44.7 bits (104), Expect = 2e-04
Identities = 58/229 (25%), Positives = 98/229 (42%), Gaps = 30/229 (13%)
Query: 159 ELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPY 218
E+L L+ DDI D+S RRG + G+ IN AN + L K+ + P
Sbjct: 54 EMLHNASLLIDDIEDNSKLRRGFPVAHSIYGIP-SVINSANYVY--FLGLEKVLTLDHP- 109
Query: 219 YLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAA 278
+ ++LF + + GQ LD+ TE+ YK++V KT +A
Sbjct: 110 --DAVKLFTRQLLELHQGQGLDIYWRDNYTCP----TEEEYKAMVLQKTGGL---FGLAV 160
Query: 279 AMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFG-DPSVTGKIGTDIQDNKCSWLV 337
+ D +++ K +L +G FFQI+DDY +L + S D+ + K S+
Sbjct: 161 GLMQLFSDYKED---LKPLLNTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPT 217
Query: 338 VQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEED 386
+ + + PE Q+ + + R + E +D+ + Y ED
Sbjct: 218 IHAIW-SRPESTQV----------QNILRQRT--ENIDIKKYCVHYLED 253
>gi|4758430 geranylgeranyl diphosphate synthase 1 isoform A [Homo
sapiens]
Length = 300
Score = 44.7 bits (104), Expect = 2e-04
Identities = 58/229 (25%), Positives = 98/229 (42%), Gaps = 30/229 (13%)
Query: 159 ELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPY 218
E+L L+ DDI D+S RRG + G+ IN AN + L K+ + P
Sbjct: 54 EMLHNASLLIDDIEDNSKLRRGFPVAHSIYGIP-SVINSANYVY--FLGLEKVLTLDHP- 109
Query: 219 YLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAA 278
+ ++LF + + GQ LD+ TE+ YK++V KT +A
Sbjct: 110 --DAVKLFTRQLLELHQGQGLDIYWRDNYTCP----TEEEYKAMVLQKTGGL---FGLAV 160
Query: 279 AMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFG-DPSVTGKIGTDIQDNKCSWLV 337
+ D +++ K +L +G FFQI+DDY +L + S D+ + K S+
Sbjct: 161 GLMQLFSDYKED---LKPLLNTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPT 217
Query: 338 VQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEED 386
+ + + PE Q+ + + R + E +D+ + Y ED
Sbjct: 218 IHAIW-SRPESTQV----------QNILRQRT--ENIDIKKYCVHYLED 253
>gi|83700223 geranylgeranyl diphosphate synthase 1 isoform B [Homo
sapiens]
Length = 246
Score = 42.7 bits (99), Expect = 6e-04
Identities = 56/222 (25%), Positives = 95/222 (42%), Gaps = 30/222 (13%)
Query: 166 LVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIEL 225
L+ DDI D+S RRG + G+ IN AN + L K+ + P + ++L
Sbjct: 7 LLIDDIEDNSKLRRGFPVAHSIYGIP-SVINSANYVY--FLGLEKVLTLDHP---DAVKL 60
Query: 226 FLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGI 285
F + + GQ LD+ TE+ YK++V KT +A +
Sbjct: 61 FTRQLLELHQGQGLDIYWRDNYTCP----TEEEYKAMVLQKTGGL---FGLAVGLMQLFS 113
Query: 286 DGEKEHANAKKILLEMGEFFQIQDDYLDLFG-DPSVTGKIGTDIQDNKCSWLVVQCLQRA 344
D +++ K +L +G FFQI+DDY +L + S D+ + K S+ + + +
Sbjct: 114 DYKED---LKPLLNTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIW-S 169
Query: 345 TPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEED 386
PE Q+ + + R + E +D+ + Y ED
Sbjct: 170 RPESTQV----------QNILRQRT--ENIDIKKYCVHYLED 199
>gi|50659086 prenyl diphosphate synthase, subunit 1 [Homo sapiens]
Length = 415
Score = 34.3 bits (77), Expect = 0.22
Identities = 55/222 (24%), Positives = 86/222 (38%), Gaps = 26/222 (11%)
Query: 109 ARLKEVLEYNAIG-GKYNRGLTVVVAFR--ELVEPRKQDADSLQRAWTVGWCVELLQAFF 165
+ LKE+ EY G GK R + V + R + + + QRA + E++
Sbjct: 119 SELKEMSEYYFDGKGKAFRPIIVALMARACNIHHNNSRHVQASQRA--IALIAEMIHTAS 176
Query: 166 LVADDIMDSSLTRRGQ----ICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLN 221
LV DD++D + +RRG+ W +K V + +L A L ++
Sbjct: 177 LVHDDVIDDASSRRGKHTVNKIWGEKKAV----LAGDLILSAASIALARI------GNTT 226
Query: 222 LIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMY 281
+I + Q G+ L L + N + EK +K KTA S A+
Sbjct: 227 VISILTQVIEDLVRGEFLQLGSKENENERFAHYLEKTFK-----KTA--SLIANSCKAVS 279
Query: 282 MAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGK 323
+ G H A + +G FQ+ DD LD GK
Sbjct: 280 VLGCPDPVVHEIAYQYGKNVGIAFQLIDDVLDFTSCSDQMGK 321
>gi|31377562 HAUS augmin-like complex, subunit 6 [Homo sapiens]
Length = 955
Score = 31.6 bits (70), Expect = 1.4
Identities = 12/38 (31%), Positives = 26/38 (68%)
Query: 362 EKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYA 399
EK+ +V++L+ ++ +FL+ E + S +++L+ QYA
Sbjct: 229 EKIQKVRSLWASVNETLMFLEKEREVVSSVLSLVNQYA 266
>gi|38505176 prostaglandin E receptor 3, subtype EP3 isoform 3 [Homo
sapiens]
Length = 393
Score = 31.2 bits (69), Expect = 1.8
Identities = 14/39 (35%), Positives = 19/39 (48%)
Query: 26 WLGSLRRPSLVHGYPVLAWHSARCWCQAWTEEPRALCSS 64
W+ L R L+ + RC+C AW + PR CSS
Sbjct: 344 WVYLLLRKILLRKFCQEMGPDGRCFCHAWRQVPRTWCSS 382
>gi|239756261 PREDICTED: similar to hect domain and RLD 2 [Homo
sapiens]
Length = 1102
Score = 30.0 bits (66), Expect = 4.1
Identities = 18/66 (27%), Positives = 32/66 (48%), Gaps = 8/66 (12%)
Query: 347 EQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSH--------IMALIEQY 398
+Q Q+ ++NY Q+ + AR + ++ L+ E++ Y+H + L Q
Sbjct: 353 QQVQLQRDNYAQQIKGERARWQQRMRKMSQEVYTLKTEKEHYTHRVEGLERSLSKLKNQM 412
Query: 399 AAPLPP 404
A PLPP
Sbjct: 413 AEPLPP 418
>gi|239750798 PREDICTED: similar to hect domain and RLD 2 [Homo
sapiens]
Length = 691
Score = 30.0 bits (66), Expect = 4.1
Identities = 18/66 (27%), Positives = 32/66 (48%), Gaps = 8/66 (12%)
Query: 347 EQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSH--------IMALIEQY 398
+Q Q+ ++NY Q+ + AR + ++ L+ E++ Y+H + L Q
Sbjct: 343 QQVQLQRDNYAQQIKGERARWQQRMRKMSQEVYTLKTEKEHYTHRVEGLERSLSKLKNQM 402
Query: 399 AAPLPP 404
A PLPP
Sbjct: 403 AEPLPP 408
>gi|239745140 PREDICTED: similar to hect domain and RLD 2 [Homo
sapiens]
Length = 1052
Score = 30.0 bits (66), Expect = 4.1
Identities = 18/66 (27%), Positives = 32/66 (48%), Gaps = 8/66 (12%)
Query: 347 EQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSH--------IMALIEQY 398
+Q Q+ ++NY Q+ + AR + ++ L+ E++ Y+H + L Q
Sbjct: 270 QQVQLQRDNYAQQIKGERARWQQRMRKMSQEVYTLKTEKEHYTHRVEGLERSLSKLKNQM 329
Query: 399 AAPLPP 404
A PLPP
Sbjct: 330 AEPLPP 335
>gi|89276764 prostaglandin E receptor 3, subtype EP3 isoform 2 [Homo
sapiens]
Length = 402
Score = 29.6 bits (65), Expect = 5.3
Identities = 10/17 (58%), Positives = 12/17 (70%)
Query: 48 RCWCQAWTEEPRALCSS 64
RC+C AW + PR CSS
Sbjct: 375 RCFCHAWRQVPRTWCSS 391
>gi|44681484 cell division cycle associated 2 [Homo sapiens]
Length = 1023
Score = 29.3 bits (64), Expect = 7.0
Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 6/66 (9%)
Query: 317 DPSVTGKIGTDIQD------NKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKAL 370
+ SV + T++Q N+ +C +RA P++ Q+LK +K K + K+L
Sbjct: 518 EESVCNLLNTEVQPCKEKKINRRKSQETKCTKRALPKKSQVLKSCRKKKGKGKKSVQKSL 577
Query: 371 YEELDL 376
Y E D+
Sbjct: 578 YGERDI 583
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,004,933
Number of Sequences: 37866
Number of extensions: 699304
Number of successful extensions: 1464
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1455
Number of HSP's gapped (non-prelim): 14
length of query: 419
length of database: 18,247,518
effective HSP length: 105
effective length of query: 314
effective length of database: 14,271,588
effective search space: 4481278632
effective search space used: 4481278632
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Search text |
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.