Search of human proteins with 205277412

Search of human proteins with 205277412

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|205277412 mitogen-activated protein kinase 9 isoform JNK2
gamma [Homo sapiens]
         (242 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|205277412 mitogen-activated protein kinase 9 isoform JNK2 gam...   490   e-139
gi|21237739 mitogen-activated protein kinase 9 isoform JNK2 alph...   467   e-132
gi|21237736 mitogen-activated protein kinase 9 isoform JNK2 alph...   467   e-132
gi|21237745 mitogen-activated protein kinase 9 isoform JNK2 beta...   447   e-126
gi|21237742 mitogen-activated protein kinase 9 isoform JNK2 beta...   447   e-126
gi|4506081 mitogen-activated protein kinase 10 isoform 1 [Homo s...   419   e-117
gi|20986510 mitogen-activated protein kinase 10 isoform 2 [Homo ...   419   e-117
gi|20986506 mitogen-activated protein kinase 10 isoform 3 [Homo ...   419   e-117
gi|20986521 mitogen-activated protein kinase 8 isoform JNK1 beta...   418   e-117
gi|20986519 mitogen-activated protein kinase 8 isoform JNK1 beta...   418   e-117
gi|20986523 mitogen-activated protein kinase 8 isoform JNK1 alph...   408   e-114
gi|4506095 mitogen-activated protein kinase 8 isoform JNK1 alpha...   408   e-114
gi|20986514 mitogen-activated protein kinase 14 isoform 3 [Homo ...   254   6e-68
gi|4503069 mitogen-activated protein kinase 14 isoform 1 [Homo s...   254   6e-68
gi|20986516 mitogen-activated protein kinase 14 isoform 4 [Homo ...   254   6e-68
gi|20986512 mitogen-activated protein kinase 14 isoform 2 [Homo ...   254   6e-68
gi|48255970 mitogen-activated protein kinase 12 [Homo sapiens]        243   8e-65
gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens]         239   1e-63
gi|20128774 mitogen-activated protein kinase 11 [Homo sapiens]        239   1e-63
gi|20986508 mitogen-activated protein kinase 10 isoform 4 [Homo ...   231   3e-61
gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s...   192   2e-49
gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ...   192   2e-49
gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ...   192   2e-49
gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens]         189   2e-48
gi|66932916 mitogen-activated protein kinase 1 [Homo sapiens]         189   2e-48
gi|158138507 mitogen-activated protein kinase 3 isoform 3 [Homo ...   186   1e-47
gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo s...   186   2e-47
gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo s...   186   2e-47
gi|149408126 nemo like kinase [Homo sapiens]                          172   3e-43
gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens]        158   5e-39

>gi|205277412 mitogen-activated protein kinase 9 isoform JNK2 gamma
           [Homo sapiens]
          Length = 242

 Score =  490 bits (1262), Expect = e-139
 Identities = 242/242 (100%), Positives = 242/242 (100%)

Query: 1   MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60
           MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
Sbjct: 1   MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60

Query: 61  FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 120
           FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
Sbjct: 61  FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 120

Query: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 180
           MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
Sbjct: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 180

Query: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDRILPRDLGPAM 240
           MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDRILPRDLGPAM
Sbjct: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDRILPRDLGPAM 240

Query: 241 LS 242
           LS
Sbjct: 241 LS 242


>gi|21237739 mitogen-activated protein kinase 9 isoform JNK2 alpha1
           [Homo sapiens]
          Length = 382

 Score =  467 bits (1201), Expect = e-132
 Identities = 230/231 (99%), Positives = 230/231 (99%)

Query: 1   MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60
           MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
Sbjct: 1   MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60

Query: 61  FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 120
           FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
Sbjct: 61  FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 120

Query: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 180
           MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
Sbjct: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 180

Query: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTD I
Sbjct: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHI 231


>gi|21237736 mitogen-activated protein kinase 9 isoform JNK2 alpha2
           [Homo sapiens]
          Length = 424

 Score =  467 bits (1201), Expect = e-132
 Identities = 230/231 (99%), Positives = 230/231 (99%)

Query: 1   MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60
           MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
Sbjct: 1   MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60

Query: 61  FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 120
           FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
Sbjct: 61  FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 120

Query: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 180
           MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
Sbjct: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 180

Query: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTD I
Sbjct: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHI 231


>gi|21237745 mitogen-activated protein kinase 9 isoform JNK2 beta2
           [Homo sapiens]
          Length = 424

 Score =  447 bits (1150), Expect = e-126
 Identities = 222/231 (96%), Positives = 224/231 (96%)

Query: 1   MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60
           MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
Sbjct: 1   MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60

Query: 61  FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 120
           FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
Sbjct: 61  FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 120

Query: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 180
           MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
Sbjct: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 180

Query: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIM E+V   V+F G D I
Sbjct: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYI 231


>gi|21237742 mitogen-activated protein kinase 9 isoform JNK2 beta1
           [Homo sapiens]
          Length = 382

 Score =  447 bits (1150), Expect = e-126
 Identities = 222/231 (96%), Positives = 224/231 (96%)

Query: 1   MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60
           MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
Sbjct: 1   MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60

Query: 61  FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 120
           FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
Sbjct: 61  FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 120

Query: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 180
           MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
Sbjct: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 180

Query: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIM E+V   V+F G D I
Sbjct: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYI 231


>gi|4506081 mitogen-activated protein kinase 10 isoform 1 [Homo
           sapiens]
          Length = 422

 Score =  419 bits (1077), Expect = e-117
 Identities = 207/231 (89%), Positives = 217/231 (93%)

Query: 1   MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60
           MS SK D+QFYSV+V DSTFTVLKRYQ LKPIGSGAQGIVCAA+D VL  NVA+KKLSRP
Sbjct: 39  MSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRP 98

Query: 61  FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 120
           FQNQTHAKRAYRELVL+KCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI 
Sbjct: 99  FQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ 158

Query: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 180
           MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTA T+F
Sbjct: 159 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF 218

Query: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGE+V+  ++F G D I
Sbjct: 219 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYI 269


>gi|20986510 mitogen-activated protein kinase 10 isoform 2 [Homo
           sapiens]
          Length = 464

 Score =  419 bits (1077), Expect = e-117
 Identities = 207/231 (89%), Positives = 217/231 (93%)

Query: 1   MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60
           MS SK D+QFYSV+V DSTFTVLKRYQ LKPIGSGAQGIVCAA+D VL  NVA+KKLSRP
Sbjct: 39  MSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRP 98

Query: 61  FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 120
           FQNQTHAKRAYRELVL+KCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI 
Sbjct: 99  FQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ 158

Query: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 180
           MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTA T+F
Sbjct: 159 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF 218

Query: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGE+V+  ++F G D I
Sbjct: 219 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYI 269


>gi|20986506 mitogen-activated protein kinase 10 isoform 3 [Homo
           sapiens]
          Length = 426

 Score =  419 bits (1077), Expect = e-117
 Identities = 207/231 (89%), Positives = 217/231 (93%)

Query: 1   MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60
           MS SK D+QFYSV+V DSTFTVLKRYQ LKPIGSGAQGIVCAA+D VL  NVA+KKLSRP
Sbjct: 1   MSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRP 60

Query: 61  FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 120
           FQNQTHAKRAYRELVL+KCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI 
Sbjct: 61  FQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ 120

Query: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 180
           MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTA T+F
Sbjct: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF 180

Query: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGE+V+  ++F G D I
Sbjct: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYI 231


>gi|20986521 mitogen-activated protein kinase 8 isoform JNK1 beta2
           [Homo sapiens]
          Length = 427

 Score =  418 bits (1075), Expect = e-117
 Identities = 204/231 (88%), Positives = 217/231 (93%)

Query: 1   MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60
           MS SK D+ FYSV++ DSTFTVLKRYQ LKPIGSGAQGIVCAA+D +L  NVA+KKLSRP
Sbjct: 1   MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP 60

Query: 61  FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 120
           FQNQTHAKRAYRELVL+KCVNHKNII LLNVFTPQK+LEEFQDVY+VMELMDANLCQVI 
Sbjct: 61  FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ 120

Query: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 180
           MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTA T+F
Sbjct: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF 180

Query: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGE++KG V+F GTD I
Sbjct: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHI 231


>gi|20986519 mitogen-activated protein kinase 8 isoform JNK1 beta1
           [Homo sapiens]
          Length = 384

 Score =  418 bits (1075), Expect = e-117
 Identities = 204/231 (88%), Positives = 217/231 (93%)

Query: 1   MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60
           MS SK D+ FYSV++ DSTFTVLKRYQ LKPIGSGAQGIVCAA+D +L  NVA+KKLSRP
Sbjct: 1   MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP 60

Query: 61  FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 120
           FQNQTHAKRAYRELVL+KCVNHKNII LLNVFTPQK+LEEFQDVY+VMELMDANLCQVI 
Sbjct: 61  FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ 120

Query: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 180
           MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTA T+F
Sbjct: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF 180

Query: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGE++KG V+F GTD I
Sbjct: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHI 231


>gi|20986523 mitogen-activated protein kinase 8 isoform JNK1 alpha2
           [Homo sapiens]
          Length = 427

 Score =  408 bits (1049), Expect = e-114
 Identities = 200/231 (86%), Positives = 214/231 (92%)

Query: 1   MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60
           MS SK D+ FYSV++ DSTFTVLKRYQ LKPIGSGAQGIVCAA+D +L  NVA+KKLSRP
Sbjct: 1   MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP 60

Query: 61  FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 120
           FQNQTHAKRAYRELVL+KCVNHKNII LLNVFTPQK+LEEFQDVY+VMELMDANLCQVI 
Sbjct: 61  FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ 120

Query: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 180
           MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTA T+F
Sbjct: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF 180

Query: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           MMTPYVVTRYYRAPEVILGMGYKENVD+WSVGCIMGE+V   ++F G D I
Sbjct: 181 MMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYI 231


>gi|4506095 mitogen-activated protein kinase 8 isoform JNK1 alpha1
           [Homo sapiens]
          Length = 384

 Score =  408 bits (1049), Expect = e-114
 Identities = 200/231 (86%), Positives = 214/231 (92%)

Query: 1   MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 60
           MS SK D+ FYSV++ DSTFTVLKRYQ LKPIGSGAQGIVCAA+D +L  NVA+KKLSRP
Sbjct: 1   MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP 60

Query: 61  FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 120
           FQNQTHAKRAYRELVL+KCVNHKNII LLNVFTPQK+LEEFQDVY+VMELMDANLCQVI 
Sbjct: 61  FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ 120

Query: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 180
           MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTA T+F
Sbjct: 121 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF 180

Query: 181 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           MMTPYVVTRYYRAPEVILGMGYKENVD+WSVGCIMGE+V   ++F G D I
Sbjct: 181 MMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYI 231


>gi|20986514 mitogen-activated protein kinase 14 isoform 3 [Homo
           sapiens]
          Length = 297

 Score =  254 bits (648), Expect = 6e-68
 Identities = 131/224 (58%), Positives = 165/224 (73%), Gaps = 4/224 (1%)

Query: 10  FYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKR 69
           FY  ++  + + V +RYQ L P+GSGA G VCAAFDT  G+ VAVKKLSRPFQ+  HAKR
Sbjct: 8   FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKR 67

Query: 70  AYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-MELDHERM 128
            YREL LLK + H+N+I LL+VFTP ++LEEF DVYLV  LM A+L  ++   +L  + +
Sbjct: 68  TYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHV 127

Query: 129 SYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVT 188
            +L+YQ+L G+K++HSA IIHRDLKPSN+ V  DC LKILDFGLAR   T+  MT YV T
Sbjct: 128 QFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARH--TDDEMTGYVAT 185

Query: 189 RYYRAPEVILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           R+YRAPE++L  M Y + VDIWSVGCIM EL+ G  +F GTD I
Sbjct: 186 RWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHI 229


>gi|4503069 mitogen-activated protein kinase 14 isoform 1 [Homo
           sapiens]
          Length = 360

 Score =  254 bits (648), Expect = 6e-68
 Identities = 131/224 (58%), Positives = 165/224 (73%), Gaps = 4/224 (1%)

Query: 10  FYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKR 69
           FY  ++  + + V +RYQ L P+GSGA G VCAAFDT  G+ VAVKKLSRPFQ+  HAKR
Sbjct: 8   FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKR 67

Query: 70  AYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-MELDHERM 128
            YREL LLK + H+N+I LL+VFTP ++LEEF DVYLV  LM A+L  ++   +L  + +
Sbjct: 68  TYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHV 127

Query: 129 SYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVT 188
            +L+YQ+L G+K++HSA IIHRDLKPSN+ V  DC LKILDFGLAR   T+  MT YV T
Sbjct: 128 QFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARH--TDDEMTGYVAT 185

Query: 189 RYYRAPEVILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           R+YRAPE++L  M Y + VDIWSVGCIM EL+ G  +F GTD I
Sbjct: 186 RWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHI 229


>gi|20986516 mitogen-activated protein kinase 14 isoform 4 [Homo
           sapiens]
          Length = 307

 Score =  254 bits (648), Expect = 6e-68
 Identities = 131/224 (58%), Positives = 165/224 (73%), Gaps = 4/224 (1%)

Query: 10  FYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKR 69
           FY  ++  + + V +RYQ L P+GSGA G VCAAFDT  G+ VAVKKLSRPFQ+  HAKR
Sbjct: 8   FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKR 67

Query: 70  AYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-MELDHERM 128
            YREL LLK + H+N+I LL+VFTP ++LEEF DVYLV  LM A+L  ++   +L  + +
Sbjct: 68  TYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHV 127

Query: 129 SYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVT 188
            +L+YQ+L G+K++HSA IIHRDLKPSN+ V  DC LKILDFGLAR   T+  MT YV T
Sbjct: 128 QFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARH--TDDEMTGYVAT 185

Query: 189 RYYRAPEVILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           R+YRAPE++L  M Y + VDIWSVGCIM EL+ G  +F GTD I
Sbjct: 186 RWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHI 229


>gi|20986512 mitogen-activated protein kinase 14 isoform 2 [Homo
           sapiens]
          Length = 360

 Score =  254 bits (648), Expect = 6e-68
 Identities = 131/224 (58%), Positives = 165/224 (73%), Gaps = 4/224 (1%)

Query: 10  FYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKR 69
           FY  ++  + + V +RYQ L P+GSGA G VCAAFDT  G+ VAVKKLSRPFQ+  HAKR
Sbjct: 8   FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKR 67

Query: 70  AYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-MELDHERM 128
            YREL LLK + H+N+I LL+VFTP ++LEEF DVYLV  LM A+L  ++   +L  + +
Sbjct: 68  TYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHV 127

Query: 129 SYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVT 188
            +L+YQ+L G+K++HSA IIHRDLKPSN+ V  DC LKILDFGLAR   T+  MT YV T
Sbjct: 128 QFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARH--TDDEMTGYVAT 185

Query: 189 RYYRAPEVILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           R+YRAPE++L  M Y + VDIWSVGCIM EL+ G  +F GTD I
Sbjct: 186 RWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHI 229


>gi|48255970 mitogen-activated protein kinase 12 [Homo sapiens]
          Length = 367

 Score =  243 bits (621), Expect = 8e-65
 Identities = 124/226 (54%), Positives = 165/226 (73%), Gaps = 4/226 (1%)

Query: 8   SQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHA 67
           S FY  +V  + + V   Y+ L+P+GSGA G VC+A D   G  VA+KKL RPFQ++  A
Sbjct: 9   SGFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFA 68

Query: 68  KRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI-HMELDHE 126
           KRAYREL LLK + H+N+I LL+VFTP +TL++F D YLVM  M  +L +++ H +L  +
Sbjct: 69  KRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKLGED 128

Query: 127 RMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYV 186
           R+ +L+YQML G++++H+AGIIHRDLKP N+ V  DC LKILDFGLAR A +   MT YV
Sbjct: 129 RIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSE--MTGYV 186

Query: 187 VTRYYRAPEVILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           VTR+YRAPEVIL  M Y + VDIWSVGCIM E++ G  +F+G+D +
Sbjct: 187 VTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHL 232


>gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens]
          Length = 365

 Score =  239 bits (611), Expect = 1e-63
 Identities = 122/221 (55%), Positives = 156/221 (70%), Gaps = 3/221 (1%)

Query: 10  FYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKR 69
           FY   V  + + + K Y     +GSGA G VC+A D   G  VA+KKLSRPFQ++  AKR
Sbjct: 9   FYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKR 68

Query: 70  AYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMS 129
           AYREL+LLK + H+N+I LL+VFTP  +L  F D YLVM  M  +L +++ ME   E++ 
Sbjct: 69  AYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIMGMEFSEEKIQ 128

Query: 130 YLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTR 189
           YL+YQML G+K++HSAG++HRDLKP N+ V  DC LKILDFGLAR A  +  MT YVVTR
Sbjct: 129 YLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHA--DAEMTGYVVTR 186

Query: 190 YYRAPEVILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTD 229
           +YRAPEVIL  M Y + VDIWSVGCIM E++ G  +F+G D
Sbjct: 187 WYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKD 227


>gi|20128774 mitogen-activated protein kinase 11 [Homo sapiens]
          Length = 364

 Score =  239 bits (611), Expect = 1e-63
 Identities = 123/224 (54%), Positives = 164/224 (73%), Gaps = 4/224 (1%)

Query: 10  FYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKR 69
           FY  ++  + + V +R Q L+P+GSGA G VC+A+D  L   VAVKKLSRPFQ+  HA+R
Sbjct: 8   FYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARR 67

Query: 70  AYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHME-LDHERM 128
            YREL LLK + H+N+I LL+VFTP  ++E+F +VYLV  LM A+L  ++  + L  E +
Sbjct: 68  TYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHV 127

Query: 129 SYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVT 188
            +L+YQ+L G+K++HSAGIIHRDLKPSN+ V  DC L+ILDFGLAR A  +  MT YV T
Sbjct: 128 QFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQA--DEEMTGYVAT 185

Query: 189 RYYRAPEVILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           R+YRAPE++L  M Y + VDIWSVGCIM EL++G  +F G+D I
Sbjct: 186 RWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYI 229


>gi|20986508 mitogen-activated protein kinase 10 isoform 4 [Homo
           sapiens]
          Length = 277

 Score =  231 bits (590), Expect = 3e-61
 Identities = 112/124 (90%), Positives = 117/124 (94%)

Query: 108 MELMDANLCQVIHMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKI 167
           MELMDANLCQVI MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKI
Sbjct: 1   MELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKI 60

Query: 168 LDFGLARTACTNFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQG 227
           LDFGLARTA T+FMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGE+V+  ++F G
Sbjct: 61  LDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPG 120

Query: 228 TDRI 231
            D I
Sbjct: 121 RDYI 124


>gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score =  192 bits (488), Expect = 2e-49
 Identities = 100/223 (44%), Positives = 147/223 (65%), Gaps = 8/223 (3%)

Query: 17  DSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVL 76
           D TF V   Y+ ++ IG+GA G+V +A   + G  VA+KK+   F   T+AKR  REL +
Sbjct: 46  DVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKI 105

Query: 77  LKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH--MELDHERMSYLLYQ 134
           LK   H NII++ ++  P     EF+ VY+V++LM+++L Q+IH    L  E + Y LYQ
Sbjct: 106 LKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQ 165

Query: 135 MLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTN-----FMMTPYVVTR 189
           +L G+K++HSA +IHRDLKPSN++V  +C LKI DFG+AR  CT+     + MT YV TR
Sbjct: 166 LLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATR 225

Query: 190 YYRAPEVILGM-GYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           +YRAPE++L +  Y + +D+WSVGCI GE++    +F G + +
Sbjct: 226 WYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYV 268


>gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score =  192 bits (488), Expect = 2e-49
 Identities = 100/223 (44%), Positives = 147/223 (65%), Gaps = 8/223 (3%)

Query: 17  DSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVL 76
           D TF V   Y+ ++ IG+GA G+V +A   + G  VA+KK+   F   T+AKR  REL +
Sbjct: 46  DVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKI 105

Query: 77  LKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH--MELDHERMSYLLYQ 134
           LK   H NII++ ++  P     EF+ VY+V++LM+++L Q+IH    L  E + Y LYQ
Sbjct: 106 LKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQ 165

Query: 135 MLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTN-----FMMTPYVVTR 189
           +L G+K++HSA +IHRDLKPSN++V  +C LKI DFG+AR  CT+     + MT YV TR
Sbjct: 166 LLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATR 225

Query: 190 YYRAPEVILGM-GYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           +YRAPE++L +  Y + +D+WSVGCI GE++    +F G + +
Sbjct: 226 WYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYV 268


>gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score =  192 bits (488), Expect = 2e-49
 Identities = 100/223 (44%), Positives = 147/223 (65%), Gaps = 8/223 (3%)

Query: 17  DSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVL 76
           D TF V   Y+ ++ IG+GA G+V +A   + G  VA+KK+   F   T+AKR  REL +
Sbjct: 46  DVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKI 105

Query: 77  LKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH--MELDHERMSYLLYQ 134
           LK   H NII++ ++  P     EF+ VY+V++LM+++L Q+IH    L  E + Y LYQ
Sbjct: 106 LKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQ 165

Query: 135 MLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTN-----FMMTPYVVTR 189
           +L G+K++HSA +IHRDLKPSN++V  +C LKI DFG+AR  CT+     + MT YV TR
Sbjct: 166 LLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATR 225

Query: 190 YYRAPEVILGM-GYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           +YRAPE++L +  Y + +D+WSVGCI GE++    +F G + +
Sbjct: 226 WYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYV 268


>gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens]
          Length = 360

 Score =  189 bits (480), Expect = 2e-48
 Identities = 97/219 (44%), Positives = 148/219 (67%), Gaps = 8/219 (3%)

Query: 15  VADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYREL 74
           V    F V  RY  L  IG GA G+VC+A+D V  + VA+KK+S PF++QT+ +R  RE+
Sbjct: 14  VRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PFEHQTYCQRTLREI 72

Query: 75  VLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHME-LDHERMSYLLY 133
            +L    H+NII + ++     T+E+ +DVY+V +LM+ +L +++  + L ++ + Y LY
Sbjct: 73  KILLRFRHENIIGINDIIRAP-TIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLY 131

Query: 134 QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF----MMTPYVVTR 189
           Q+L G+K++HSA ++HRDLKPSN+++ + C LKI DFGLAR A  +      +T YV TR
Sbjct: 132 QILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATR 191

Query: 190 YYRAPEVIL-GMGYKENVDIWSVGCIMGELVKGCVIFQG 227
           +YRAPE++L   GY +++DIWSVGCI+ E++    IF G
Sbjct: 192 WYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPG 230


>gi|66932916 mitogen-activated protein kinase 1 [Homo sapiens]
          Length = 360

 Score =  189 bits (480), Expect = 2e-48
 Identities = 97/219 (44%), Positives = 148/219 (67%), Gaps = 8/219 (3%)

Query: 15  VADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYREL 74
           V    F V  RY  L  IG GA G+VC+A+D V  + VA+KK+S PF++QT+ +R  RE+
Sbjct: 14  VRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PFEHQTYCQRTLREI 72

Query: 75  VLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHME-LDHERMSYLLY 133
            +L    H+NII + ++     T+E+ +DVY+V +LM+ +L +++  + L ++ + Y LY
Sbjct: 73  KILLRFRHENIIGINDIIRAP-TIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLY 131

Query: 134 QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF----MMTPYVVTR 189
           Q+L G+K++HSA ++HRDLKPSN+++ + C LKI DFGLAR A  +      +T YV TR
Sbjct: 132 QILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATR 191

Query: 190 YYRAPEVIL-GMGYKENVDIWSVGCIMGELVKGCVIFQG 227
           +YRAPE++L   GY +++DIWSVGCI+ E++    IF G
Sbjct: 192 WYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPG 230


>gi|158138507 mitogen-activated protein kinase 3 isoform 3 [Homo
           sapiens]
          Length = 335

 Score =  186 bits (473), Expect = 1e-47
 Identities = 103/240 (42%), Positives = 154/240 (64%), Gaps = 14/240 (5%)

Query: 15  VADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYREL 74
           V    F V  RY QL+ IG GA G+V +A+D V    VA+KK+S PF++QT+ +R  RE+
Sbjct: 31  VKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREI 89

Query: 75  VLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-MELDHERMSYLLY 133
            +L    H+N+I + ++     TLE  +DVY+V +LM+ +L +++   +L ++ + Y LY
Sbjct: 90  QILLRFRHENVIGIRDILRAS-TLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLY 148

Query: 134 QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF----MMTPYVVTR 189
           Q+L G+K++HSA ++HRDLKPSN+++ + C LKI DFGLAR A         +T YV TR
Sbjct: 149 QILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATR 208

Query: 190 YYRAPEVIL-GMGYKENVDIWSVGCIMGELVKGCVIFQG------TDRILPRDLGPAMLS 242
           +YRAPE++L   GY +++DIWSVGCI+ E++    IF G       + IL  DL   ML+
Sbjct: 209 WYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILALDLLDRMLT 268


>gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo
           sapiens]
          Length = 357

 Score =  186 bits (471), Expect = 2e-47
 Identities = 97/219 (44%), Positives = 146/219 (66%), Gaps = 8/219 (3%)

Query: 15  VADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYREL 74
           V    F V  RY QL+ IG GA G+V +A+D V    VA+KK+S PF++QT+ +R  RE+
Sbjct: 31  VKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREI 89

Query: 75  VLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-MELDHERMSYLLY 133
            +L    H+N+I + ++     TLE  +DVY+V +LM+ +L +++   +L ++ + Y LY
Sbjct: 90  QILLRFRHENVIGIRDILRAS-TLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLY 148

Query: 134 QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF----MMTPYVVTR 189
           Q+L G+K++HSA ++HRDLKPSN+++ + C LKI DFGLAR A         +T YV TR
Sbjct: 149 QILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATR 208

Query: 190 YYRAPEVIL-GMGYKENVDIWSVGCIMGELVKGCVIFQG 227
           +YRAPE++L   GY +++DIWSVGCI+ E++    IF G
Sbjct: 209 WYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPG 247


>gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo
           sapiens]
          Length = 379

 Score =  186 bits (471), Expect = 2e-47
 Identities = 97/219 (44%), Positives = 146/219 (66%), Gaps = 8/219 (3%)

Query: 15  VADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYREL 74
           V    F V  RY QL+ IG GA G+V +A+D V    VA+KK+S PF++QT+ +R  RE+
Sbjct: 31  VKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREI 89

Query: 75  VLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-MELDHERMSYLLY 133
            +L    H+N+I + ++     TLE  +DVY+V +LM+ +L +++   +L ++ + Y LY
Sbjct: 90  QILLRFRHENVIGIRDILRAS-TLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLY 148

Query: 134 QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF----MMTPYVVTR 189
           Q+L G+K++HSA ++HRDLKPSN+++ + C LKI DFGLAR A         +T YV TR
Sbjct: 149 QILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATR 208

Query: 190 YYRAPEVIL-GMGYKENVDIWSVGCIMGELVKGCVIFQG 227
           +YRAPE++L   GY +++DIWSVGCI+ E++    IF G
Sbjct: 209 WYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPG 247


>gi|149408126 nemo like kinase [Homo sapiens]
          Length = 527

 Score =  172 bits (435), Expect = 3e-43
 Identities = 94/212 (44%), Positives = 135/212 (63%), Gaps = 6/212 (2%)

Query: 30  KPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLL 89
           +PIG GA G+V +  D   G  VA+KK+   FQN    KR +REL +L    H N++S L
Sbjct: 142 RPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSAL 201

Query: 90  NVFTPQKTLEEFQDVYLVMELMDANLCQVI--HMELDHERMSYLLYQMLCGIKHLHSAGI 147
           ++  P   ++ F+++Y+V ELM ++L ++I     L  + +   LYQ+L G+K+LHSAGI
Sbjct: 202 DILQPPH-IDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGI 260

Query: 148 IHRDLKPSNIVVKSDCTLKILDFGLART--ACTNFMMTPYVVTRYYRAPEVILGMGYKEN 205
           +HRD+KP N++V S+C LKI DFGLAR      +  MT  VVT+YYRAPE+++G  +  N
Sbjct: 261 LHRDIKPGNLLVNSNCVLKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSN 320

Query: 206 -VDIWSVGCIMGELVKGCVIFQGTDRILPRDL 236
            +DIWSVGCI  EL+   ++FQ    I   DL
Sbjct: 321 AIDIWSVGCIFAELLGRRILFQAQSPIQQLDL 352


>gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens]
          Length = 544

 Score =  158 bits (399), Expect = 5e-39
 Identities = 91/220 (41%), Positives = 136/220 (61%), Gaps = 14/220 (6%)

Query: 22  VLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCV- 80
           +++RY   + +G GA GIV  A D   G  VA+KK+   F+++T A+R +RE+ LL+   
Sbjct: 9   IVRRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFG 68

Query: 81  NHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHME--LDHERMSYLLYQMLCG 138
           +H NIISLL+V       E  +D+YLV E MD +L  VI     L    +  + YQ+L  
Sbjct: 69  DHPNIISLLDVIRA----ENDRDIYLVFEFMDTDLNAVIRKGGLLQDVHVRSIFYQLLRA 124

Query: 139 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART------ACTNFMMTPYVVTRYYR 192
            + LHS  ++HRD KPSN+++ ++CT+K+ DFGLAR+         +  +T YV TR+YR
Sbjct: 125 TRFLHSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYR 184

Query: 193 APEVILGM-GYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231
           APEV+L    Y   VD+WS+GCI+GE+++G  +F GT  +
Sbjct: 185 APEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTL 224


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.139    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,704,769
Number of Sequences: 37866
Number of extensions: 352641
Number of successful extensions: 2648
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 751
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 764
Number of HSP's gapped (non-prelim): 861
length of query: 242
length of database: 18,247,518
effective HSP length: 99
effective length of query: 143
effective length of database: 14,498,784
effective search space: 2073326112
effective search space used: 2073326112
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.