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Search of human proteins with 203098995
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|203098995 solute carrier family 2 (facilitated glucose
transporter), member 13 [Homo sapiens]
(648 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|203098995 solute carrier family 2 (facilitated glucose transp... 1291 0.0
gi|21553331 solute carrier family 2 (facilitated glucose transpo... 244 1e-64
gi|13540547 solute carrier family 2 member 10 [Homo sapiens] 196 4e-50
gi|5902090 solute carrier family 2 (facilitated glucose transpor... 169 1e-41
gi|223029432 solute carrier family 2 (facilitated glucose transp... 164 3e-40
gi|23592238 glucose transporter 14 [Homo sapiens] 162 1e-39
gi|4507011 glucose transporter 4 [Homo sapiens] 152 9e-37
gi|166795299 solute carrier family 2 (facilitated glucose transp... 150 3e-36
gi|4557851 solute carrier family 2 (facilitated glucose transpor... 148 2e-35
gi|4507013 solute carrier family 2 (facilitated glucose/fructose... 145 1e-34
gi|21361449 solute carrier family 2 (facilitated glucose transpo... 142 1e-33
gi|134053883 intestinal facilitative glucose transporter 7 [Homo... 130 4e-30
gi|223029430 solute carrier family 2 (facilitated glucose transp... 121 2e-27
gi|47933389 solute carrier family 2, member 9 protein isoform 2 ... 115 2e-25
gi|47933387 solute carrier family 2, member 9 protein isoform 1 ... 115 2e-25
gi|190684655 glucose transporter protein 10 isoform a [Homo sapi... 93 7e-19
gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens] 93 7e-19
gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens] 93 7e-19
gi|207447703 solute carrier family 2 (facilitated glucose/fructo... 66 1e-10
gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens] 60 5e-09
gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa... 59 2e-08
gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa... 59 2e-08
gi|24308167 SV2 related protein [Homo sapiens] 59 2e-08
gi|24497499 solute carrier family 22 member 8 [Homo sapiens] 56 1e-07
gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens] 55 2e-07
gi|63999576 solute carrier family 22, member 17 isoform b [Homo ... 55 3e-07
gi|21361834 solute carrier family 22, member 17 isoform a [Homo ... 55 3e-07
gi|4507005 solute carrier family 22 member 5 [Homo sapiens] 54 3e-07
gi|166064021 solute carrier family 22 (organic anion transporter... 54 4e-07
gi|213021148 SVOP-like isoform 1 [Homo sapiens] 53 8e-07
>gi|203098995 solute carrier family 2 (facilitated glucose
transporter), member 13 [Homo sapiens]
Length = 648
Score = 1291 bits (3341), Expect = 0.0
Identities = 648/648 (100%), Positives = 648/648 (100%)
Query: 1 MSRKASENVEYTLRSLSSLMGERRRKQPEPDAASAAGECSLLAAAESSTSLQSAGAGGGG 60
MSRKASENVEYTLRSLSSLMGERRRKQPEPDAASAAGECSLLAAAESSTSLQSAGAGGGG
Sbjct: 1 MSRKASENVEYTLRSLSSLMGERRRKQPEPDAASAAGECSLLAAAESSTSLQSAGAGGGG 60
Query: 61 VGDLERAARRQFQQDETPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQ 120
VGDLERAARRQFQQDETPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQ
Sbjct: 61 VGDLERAARRQFQQDETPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQ 120
Query: 121 ELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLV 180
ELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLV
Sbjct: 121 ELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLV 180
Query: 181 VGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRY 240
VGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRY
Sbjct: 181 VGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRY 240
Query: 241 MLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIE 300
MLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIE
Sbjct: 241 MLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIE 300
Query: 301 EEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDD 360
EEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDD
Sbjct: 301 EEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDD 360
Query: 361 RLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSP 420
RLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSP
Sbjct: 361 RLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSP 420
Query: 421 RITFKPIAPSGQNATCTRYSYCNECMLDPDCGFCYKMNKSTVIDSSCVPVNKASTNEAAW 480
RITFKPIAPSGQNATCTRYSYCNECMLDPDCGFCYKMNKSTVIDSSCVPVNKASTNEAAW
Sbjct: 421 RITFKPIAPSGQNATCTRYSYCNECMLDPDCGFCYKMNKSTVIDSSCVPVNKASTNEAAW 480
Query: 481 GRCENETKFKTEDIFWAYNFCPTPYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWA 540
GRCENETKFKTEDIFWAYNFCPTPYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWA
Sbjct: 481 GRCENETKFKTEDIFWAYNFCPTPYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWA 540
Query: 541 RSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGK 600
RSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGK
Sbjct: 541 RSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGK 600
Query: 601 KLEEIESLFDNRLCTCGTSDSDEGRYIEYIRVKGSNYHLSDNDASDVE 648
KLEEIESLFDNRLCTCGTSDSDEGRYIEYIRVKGSNYHLSDNDASDVE
Sbjct: 601 KLEEIESLFDNRLCTCGTSDSDEGRYIEYIRVKGSNYHLSDNDASDVE 648
>gi|21553331 solute carrier family 2 (facilitated glucose
transporter), member 12 [Homo sapiens]
Length = 617
Score = 244 bits (624), Expect = 1e-64
Identities = 165/536 (30%), Positives = 273/536 (50%), Gaps = 24/536 (4%)
Query: 80 FVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVSSTVGAAAVSALAGG 139
F ++ +V +A+ G L GY+ G++SGA+L +K L+L QE++VSS V A +++L GG
Sbjct: 39 FTFLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCHEQEMVVSSLVIGALLASLTGG 98
Query: 140 ALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEV 199
L +GRR AI+L+S L GS VL + + L+ GR+ +G+ I ++S+ VYIAE+
Sbjct: 99 VLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEI 158
Query: 200 SPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFLFL 259
+P + RG LV++N L I G A + + AF+ + GW+YM GL V+Q FL
Sbjct: 159 APQHRRGLLVSLNELMIVIGILSAYISNYAFANV-FHGWKYMFGLVIPLGVLQAIAMYFL 217
Query: 260 PESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGPVICRMLSY 319
P SPR+L+ KGQ A ++L ++R EE IK+++++E + S
Sbjct: 218 PPSPRFLVMKGQEGAASKVLGRLRALSDTTEELTVIKSSLKDEYQY-----SFWDLFRSK 272
Query: 320 PPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTAFTNFIFTL 379
R +++G L F Q++G I++Y++T+L+ G + + A ++ I T+
Sbjct: 273 DNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTI 332
Query: 380 VGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPRITFKPIAPSGQNATCT-- 437
LV+ VG + TF + + +A ++ +G V ++ + F I S + +
Sbjct: 333 PATLLVDHVGSK--TFLCIGSSVMAASLVTMGIV---NLNIHMNFTHICRSHNSINQSLD 387
Query: 438 --------RYSYCNECMLDPDCGFCYKMNKSTVIDSSCVPVNKASTNEAAWGRCENETKF 489
S N + D G S + + V +T+ + + T++
Sbjct: 388 ESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHTEY 447
Query: 490 KTEDIFWAYNFCPTPYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSS 549
+ I P W +L L++Y+ F+ G+GPMPW V SEI+P R A +S
Sbjct: 448 Q---IVTDPGDVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTS 504
Query: 550 GINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEI 605
+NW N+L+SLTFL + + F+Y + LLF+ +PETKG LE+I
Sbjct: 505 SMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQI 560
>gi|13540547 solute carrier family 2 member 10 [Homo sapiens]
Length = 541
Score = 196 bits (499), Expect = 4e-50
Identities = 165/573 (28%), Positives = 246/573 (42%), Gaps = 56/573 (9%)
Query: 77 TPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVSSTVGAAAVSAL 136
+P + + A S LGG FGY+ V+SGA+L L+ L L QE LV S + A +++L
Sbjct: 4 SPPVLPLCASVSLLGGLTFGYELAVISGALLPLQLDFGLSCLEQEFLVGSLLLGALLASL 63
Query: 137 AGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYI 196
GG L +GR+ AIL ++ + AGS L A + L+ GR VVG I ++SM +Y+
Sbjct: 64 VGGFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACCIYV 123
Query: 197 AEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGF 256
+E+ P RG LV++ IT G + ++ A + GWR+M G A PAV+Q
Sbjct: 124 SELVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPW-GWRHMFGWATAPAVLQSLSL 182
Query: 257 LFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGP----- 311
LFLP +E + K+ I + E GP
Sbjct: 183 LFLPAG--------------------------TDETATHKDLIPLQGGEAPKLGPGRPRY 216
Query: 312 -VICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVT 370
+ + R VG GL +FQQL+G ++ Y++TI G A+ +
Sbjct: 217 SFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSSAVLASVGL 276
Query: 371 AFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPRITFKPIAPS 430
TL + LV++ GRR L A +AL + +G V A P
Sbjct: 277 GAVKVAATLTAMGLVDRAGRRALLLAGCA--LMALSVSGIGLVSFA-----------VPM 323
Query: 431 GQNATCTRY-SYCNECMLDPDCGFCYKMNKSTV---IDSSCVPVNKASTNEAAWGRCENE 486
+C + + L D G + + + P+ + R +
Sbjct: 324 DSGPSCLAVPNATGQTGLPGDSGLLQDSSLPPIPRTNEDQREPILSTAKKTKPHPRSGDP 383
Query: 487 TKFKTEDIFWAYNFCPTP------YSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWA 540
+ + A P P WTALL L++++ F+ G GP+ W V SEIYP+
Sbjct: 384 SAPPRLALSSALPGPPLPARGHALLRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEI 443
Query: 541 RSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGK 600
R A + NW N+ +SL+FL + F LY A +GL FIY +PETKG+
Sbjct: 444 RGRAFAFCNSFNWAANLFISLSFLDLIGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQ 503
Query: 601 KLEEIESLFDNRLCTCGTSDSDEGRYIEYIRVK 633
L EI+ F R T I Y R++
Sbjct: 504 SLAEIDQQFQKRRFTLSFGHRQNSTGIPYSRIE 536
>gi|5902090 solute carrier family 2 (facilitated glucose
transporter), member 3 [Homo sapiens]
Length = 496
Score = 169 bits (427), Expect = 1e-41
Identities = 115/360 (31%), Positives = 184/360 (51%), Gaps = 27/360 (7%)
Query: 74 QDETPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKR---------------QLSLDAL 118
Q TPA ++ + V + +G F FGY+TGV++ ++K ++ L +L
Sbjct: 4 QKVTPALIFAITV-ATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSL 62
Query: 119 WQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLA---AANNKETLL 175
W + +VG S G +N FGRR ++L+ + L G + A + E L+
Sbjct: 63 WSLSVAIFSVGGMIGSFSVGLFVNR-FGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLI 121
Query: 176 AGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQK 235
GRLV+GL G+ + VP+YI E+SP LRG T+N L I G A + F +
Sbjct: 122 LGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSE 181
Query: 236 DGWRYMLGLAAVPAVIQFFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDS 294
+ W +LG +PA++Q F PESPR+ LI + + + A++IL ++ G Q + ++
Sbjct: 182 ELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQE 241
Query: 295 IKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQM 354
+K+ +E + R+ SY R+ +I+ LQ+ QQLSGIN + YYS I +
Sbjct: 242 MKDESARMSQEKQVTVLELFRVSSY---RQPIIISIVLQLSQQLSGINAVFYYSTGIFKD 298
Query: 355 SGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVL 414
+GV++ A A V N IFT+V ++LVE+ GRR L L G ++ + +L
Sbjct: 299 AGVQEPIYATIGAGV---VNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLL 355
Score = 68.6 bits (166), Expect = 2e-11
Identities = 36/117 (30%), Positives = 58/117 (49%), Gaps = 1/117 (0%)
Query: 506 SWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLH 565
S+ + +++++ FF G GP+PW + +E++ R A + NW N LV L F
Sbjct: 363 SFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPS 422
Query: 566 TAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNRLCTCGTSDSD 622
A YL Y F ++ GF L F + +PET+G+ E+I F+ + S D
Sbjct: 423 AAHYLGAY-VFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKD 478
>gi|223029432 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 1 [Homo sapiens]
Length = 507
Score = 164 bits (414), Expect = 3e-40
Identities = 142/543 (26%), Positives = 232/543 (42%), Gaps = 96/543 (17%)
Query: 81 VYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVS-----STVGAAAVSA 135
V++ + LG F FGY S + L+R L D + S T+GAAA
Sbjct: 38 VFLATFAAVLGNFSFGYALVYTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAA-GG 96
Query: 136 LAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVY 195
L+ LN + GR+ +I+ ++ AG A++A A+ LL GR + G G+ + +PVY
Sbjct: 97 LSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVY 156
Query: 196 IAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFG 255
++E++PP +RG L L F S+ A L WR++ P +I
Sbjct: 157 VSEIAPPGVRGALGATPQLMAV----FGSLSLYALGLLLP--WRWLAVAGEAPVLIMILL 210
Query: 256 FLFLPESPRWLIQKGQTQKARRILSQMRGNQT-IDEEYDSIKNNIEEEEKEVGSA---GP 311
F+P SPR+L+ +G+ ++A R L+ +RG + E++ I++N+ + V A P
Sbjct: 211 LSFMPNSPRFLLSRGRDEEALRALAWLRGTDVDVHWEFEQIQDNVRRQSSRVSWAEARAP 270
Query: 312 VICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGV----EDDRLAIWLA 367
+CR P AL+ +++ QQL+GI I+ Y +I + V +DD A
Sbjct: 271 HVCR-----PITVALL----MRLLQQLTGITPILVYLQSIFDSTAVLLPPKDD------A 315
Query: 368 SVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPRITFKPI 427
++ + L+ ++ GR+ L F S A A + L L PR P+
Sbjct: 316 AIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLG----LYIHFGPR----PL 367
Query: 428 APSGQNATCTRYSYCNECMLDPDCGFCYKMNKSTVIDSSCVPVNKASTNEAAWGRCENET 487
+P+ + A +WG
Sbjct: 368 SPN----------------------------------------STAGLESESWGDLAQPL 387
Query: 488 KFKTEDIFWAYNFCPTPY-SWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNA 546
P Y + LL +L+++ +A G GP+ W + SE+ PL AR +
Sbjct: 388 A------------APAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVASG 435
Query: 547 CSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIE 606
+W+ +++ +FL FF +A V L+F C+PETKG+ LE+IE
Sbjct: 436 LCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIE 495
Query: 607 SLF 609
S F
Sbjct: 496 SFF 498
>gi|23592238 glucose transporter 14 [Homo sapiens]
Length = 520
Score = 162 bits (409), Expect = 1e-39
Identities = 113/357 (31%), Positives = 179/357 (50%), Gaps = 27/357 (7%)
Query: 77 TPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKR---------------QLSLDALWQE 121
TPA ++ + V + +G F FGY+TGV++ ++K ++ L LW
Sbjct: 31 TPALIFAITV-ATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSL 89
Query: 122 LLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAA---ANNKETLLAGR 178
+ +VG S G +N FGRR ++L+ + L G ++ A + E L+ GR
Sbjct: 90 SVAIFSVGGMIGSFSVGLFVNR-FGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGR 148
Query: 179 LVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGW 238
LV+GL G+ + VP+YI E+SP LRG T+N L I G A + ++ W
Sbjct: 149 LVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELW 208
Query: 239 RYMLGLAAVPAVIQFFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDSIKN 297
+LG +PA++Q PESPR+ LI + + + A RIL ++ G Q + ++ +K+
Sbjct: 209 PVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKD 268
Query: 298 NIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGV 357
+E + R+ SY R+ +I+ LQ+ QQLSGIN + YYS I + +GV
Sbjct: 269 ESARMSQEKQVTVLELFRVSSY---RQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV 325
Query: 358 EDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVL 414
+ A A V N IFTL+ ++LVE+ GRR L L G ++ + +L
Sbjct: 326 QQPIYATISAGV---VNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLL 379
Score = 64.7 bits (156), Expect = 3e-10
Identities = 35/117 (29%), Positives = 57/117 (48%), Gaps = 1/117 (0%)
Query: 506 SWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLH 565
S+ + +++++ F G GP+PW + +E++ R A + NW N LV L F
Sbjct: 387 SFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPS 446
Query: 566 TAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNRLCTCGTSDSD 622
A YL Y F ++ GF L F + +PET+G+ E+I F+ + S D
Sbjct: 447 AAYYLGAY-VFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKD 502
>gi|4507011 glucose transporter 4 [Homo sapiens]
Length = 509
Score = 152 bits (384), Expect = 9e-37
Identities = 123/384 (32%), Positives = 194/384 (50%), Gaps = 46/384 (11%)
Query: 83 VVAVFSA-LGGFLFGYDTGVVSGAMLLLKRQLS-------------------LDALWQEL 122
V+AVFSA LG FGY+ GV++ ++++ + L LW
Sbjct: 25 VLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWALS 84
Query: 123 LVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAAN---NKETLLAGRL 179
+ +VG +S+ G ++ GR+ A+L+ + L G +++ AN + E L+ GR
Sbjct: 85 VAIFSVGGM-ISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRF 143
Query: 180 VVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDG-W 238
++G G+ S VP+Y+ E++P +LRG L T+N L I G A V+ G S L W
Sbjct: 144 LIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVL-GLESLLGTASLW 202
Query: 239 RYMLGLAAVPAVIQFFGFLFLPESPRWL-IQKGQTQKARRILSQMRGNQTIDEEYDSIKN 297
+LGL +PA++Q F PESPR+L I + AR+ L ++ G + +
Sbjct: 203 PLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADV----SGVLA 258
Query: 298 NIEEEEKEVGSAGPV-ICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSG 356
+++E++++ P+ + ++L R+ LI+ LQ+ QQLSGIN + YYS +I + +G
Sbjct: 259 ELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAG 318
Query: 357 VEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAG-------TTVALIIL- 408
V A A V N +FTLV V LVE+ GRR L LAG TVAL++L
Sbjct: 319 VGQPAYATIGAGV---VNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLE 375
Query: 409 ---ALGFVLSAQVSPRITFKPIAP 429
A+ +V + + F I P
Sbjct: 376 RVPAMSYVSIVAIFGFVAFFEIGP 399
Score = 58.2 bits (139), Expect = 2e-08
Identities = 28/104 (26%), Positives = 55/104 (52%), Gaps = 1/104 (0%)
Query: 506 SWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLH 565
S+ +++ + ++ FF G GP+PW + +E++ R A + NW N ++ + F +
Sbjct: 381 SYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQY 440
Query: 566 TAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLF 609
AE + Y F L+A +F + +PET+G+ ++I + F
Sbjct: 441 VAEAMGPY-VFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAF 483
>gi|166795299 solute carrier family 2 (facilitated glucose
transporter), member 1 [Homo sapiens]
Length = 492
Score = 150 bits (380), Expect = 3e-36
Identities = 101/350 (28%), Positives = 172/350 (49%), Gaps = 26/350 (7%)
Query: 88 SALGGFLFGYDTGVVSGAMLLLKR---------------QLSLDALWQELLVSSTVGAAA 132
+ LG FGY+TGV++ +++ +L LW + +VG
Sbjct: 19 AVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMI 78
Query: 133 VSALAGGALNGVFGRRAAILLASALFTAGSAVLAAAN---NKETLLAGRLVVGLGIGIAS 189
S G +N FGRR ++L+ + L + ++ + + E L+ GR ++G+ G+ +
Sbjct: 79 GSFSVGLFVNR-FGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTT 137
Query: 190 MTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPA 249
VP+Y+ EVSP LRG L T++ L I G A V KD W +L + +PA
Sbjct: 138 GFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPA 197
Query: 250 VIQFFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGS 308
++Q F PESPR+ LI + + +A+ +L ++RG + + +K EE + +
Sbjct: 198 LLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMK---EESRQMMRE 254
Query: 309 AGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLAS 368
I + P R+ +++ LQ+ QQLSGIN + YYS +I + +GV+ ++
Sbjct: 255 KKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQ---PVYATI 311
Query: 369 VTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQV 418
+ N FT+V +++VE+ GRR L LAG I++ + L Q+
Sbjct: 312 GSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQL 361
Score = 58.9 bits (141), Expect = 1e-08
Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 5/118 (4%)
Query: 506 SWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLH 565
S+ +++ + ++ FF G GP+PW + +E++ R A + NW N +V + F +
Sbjct: 365 SYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQY 424
Query: 566 TAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNRLCTCGTSDSDE 623
+ Y F ++ + +F Y +PETKG+ +EI S F G S SD+
Sbjct: 425 VEQLCGPY-VFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQG----GASQSDK 477
>gi|4557851 solute carrier family 2 (facilitated glucose
transporter), member 2 [Homo sapiens]
Length = 524
Score = 148 bits (373), Expect = 2e-35
Identities = 98/301 (32%), Positives = 156/301 (51%), Gaps = 11/301 (3%)
Query: 118 LWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAAN---NKETL 174
LW L VSS ++ GG L GR A+L+A+ L G+ ++ + + +
Sbjct: 96 LWS-LSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILI 154
Query: 175 LAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQ 234
+AGR + GL G+ S VP+YI E++P LRG L T + L I G + ++ F
Sbjct: 155 IAGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGN 214
Query: 235 KDGWRYMLGLAAVPAVIQFFGFLFLPESPRWL-IQKGQTQKARRILSQMRGNQTIDEEYD 293
D W +LGL+ V A++Q F PESPR+L I+ + KA++ L ++RG + ++ +
Sbjct: 215 YDLWHILLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDIN 274
Query: 294 SIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQ 353
++ EE E + I ++ + R+ ++V L + QQ SGIN I YYS +I Q
Sbjct: 275 EMRKEREEASSEQKVS---IIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQ 331
Query: 354 MSGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFV 413
+G+ ++ N +FT V V+LVEK GRR L ++G V I +++G V
Sbjct: 332 TAGISK---PVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLV 388
Query: 414 L 414
L
Sbjct: 389 L 389
Score = 72.4 bits (176), Expect = 1e-12
Identities = 37/107 (34%), Positives = 60/107 (56%), Gaps = 1/107 (0%)
Query: 506 SWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLH 565
S+ +++ + L++ FF G GP+PW + +E + R A ++ NW N +V+L F +
Sbjct: 397 SYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQY 456
Query: 566 TAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNR 612
A++ Y FFL+AG LF + +PETKGK EEI + F +
Sbjct: 457 IADFCGPY-VFFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQKK 502
>gi|4507013 solute carrier family 2 (facilitated glucose/fructose
transporter), member 5 isoform 1 [Homo sapiens]
Length = 501
Score = 145 bits (365), Expect = 1e-34
Identities = 109/361 (30%), Positives = 171/361 (47%), Gaps = 28/361 (7%)
Query: 79 AFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKR---------------QLSLDALWQELL 123
A ++A F + F +GY+ V+ LL+++ L LW +
Sbjct: 18 ALATLIAAFGS--SFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWSVTV 75
Query: 124 VSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAA----ANNKETLLAGRL 179
G S L G +N FGR+ A+L + +F+ A+L A + E ++ RL
Sbjct: 76 SMFPFGGFIGSLLVGPLVNK-FGRKGALLFNN-IFSIVPAILMGCSRVATSFELIIISRL 133
Query: 180 VVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWR 239
+VG+ G++S VP+Y+ E++P NLRG L + LFIT G A + DGW
Sbjct: 134 LVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWP 193
Query: 240 YMLGLAAVPAVIQFFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDSIKNN 298
+LGL VPA +Q F PESPR+ LIQK A++ L +RG ++D E I+
Sbjct: 194 ILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIR-- 251
Query: 299 IEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVE 358
+E+E E + + ++ R L+ L QQLSG+N I YY+ I +GV
Sbjct: 252 -QEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVP 310
Query: 359 DDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQV 418
++ + ++ + T N + T V++VE +GRR L + +A +L L V
Sbjct: 311 EEHVQ-YVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTV 369
Query: 419 S 419
S
Sbjct: 370 S 370
Score = 47.4 bits (111), Expect = 4e-05
Identities = 28/103 (27%), Positives = 53/103 (51%), Gaps = 1/103 (0%)
Query: 507 WTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHT 566
+ +++ +I Y++ A G P+P + +EI+ +R + ++W+ N V L F
Sbjct: 374 YISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFI 433
Query: 567 AEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLF 609
E L Y +F ++A + ++I+ +PETK K EI +F
Sbjct: 434 QEGLGPY-SFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIF 475
>gi|21361449 solute carrier family 2 (facilitated glucose
transporter), member 8 [Homo sapiens]
Length = 477
Score = 142 bits (357), Expect = 1e-33
Identities = 101/335 (30%), Positives = 158/335 (47%), Gaps = 27/335 (8%)
Query: 81 VYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVSSTVGAAAVSALAGGA 140
V++ A +ALG FG+ G S A+ L+R + S + A AGG
Sbjct: 26 VFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPPAPRLDDAAASWFGAVVTLGAAAGGV 85
Query: 141 LNGVF----GRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYI 196
L G GR+ ++LL S F AG AV+ AA + LL GRL+ GL G+AS+ PVYI
Sbjct: 86 LGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLACGVASLVAPVYI 145
Query: 197 AEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGF 256
+E++ P +RG L + L + G A + WR++ L VP +
Sbjct: 146 SEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLE------WRWLAVLGCVPPSLMLLLM 199
Query: 257 LFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGPVICRM 316
F+PE+PR+L+ + + Q+A L + G++ E+ +G+ +
Sbjct: 200 CFMPETPRFLLTQHRRQEAMAALRFLWGSEQ------------GWEDPPIGAEQSFHLAL 247
Query: 317 LSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTAFTNFI 376
L P + I+G L FQQLSG+N +M+Y+ TI + + +D LA + V +
Sbjct: 248 LRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLA---SVVVGVIQVL 304
Query: 377 FTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALG 411
FT V ++++ GRR L L+G + A G
Sbjct: 305 FTAVAALIMDRAGRRLLLV--LSGVVMVFSTSAFG 337
Score = 85.9 bits (211), Expect = 1e-16
Identities = 42/107 (39%), Positives = 60/107 (56%)
Query: 506 SWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLH 565
+W A+ + L++ FA G GP+PW + SEI+PL + NW+ LV+ F
Sbjct: 371 AWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSS 430
Query: 566 TAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNR 612
E L YGAF+L + F +LF C+PETKGK LE+I + F+ R
Sbjct: 431 LMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR 477
>gi|134053883 intestinal facilitative glucose transporter 7 [Homo
sapiens]
Length = 512
Score = 130 bits (327), Expect = 4e-30
Identities = 105/363 (28%), Positives = 174/363 (47%), Gaps = 27/363 (7%)
Query: 83 VVAVFSALGG--FLFGYDTGVVSGAMLLLKRQLS----------LDALWQELLVSSTVGA 130
++A SA G F +GY+ VV+ + K + +D LL S TV
Sbjct: 24 LLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLMLLLWSCTVSM 83
Query: 131 AAVSALAGGALNGVF----GRRAAILLASALFTAGSAVLAAANNK----ETLLAGRLVVG 182
+ L G L G+ GR+ +L+ + +F A+L + E ++ R+V+G
Sbjct: 84 FPLGGLLGSLLVGLLVDSCGRKGTLLINN-IFAIIPAILMGVSKVAKAFELIVFSRVVLG 142
Query: 183 LGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYML 242
+ GI+ +P+Y+ E++P NLRG + T+ +F+ G F A + GW +L
Sbjct: 143 VCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPVLL 202
Query: 243 GLAAVPAVIQFFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEE 301
L VPA++Q F PESPR+ LIQKG AR+ L ++RG+ ++ E + ++
Sbjct: 203 ALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMRAEARA 262
Query: 302 EEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDR 361
E E + +C + S ++IV L QQLSGIN I YY+ TI +GVE
Sbjct: 263 ERAEGHLSVLHLCALRSLRWQLLSIIV---LMAGQQLSGINAINYYADTIYTSAGVEAAH 319
Query: 362 LAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPR 421
+ ++ + N + T+ LVE++GRR L A ++L + + +V P
Sbjct: 320 -SQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRV-PE 377
Query: 422 ITF 424
+++
Sbjct: 378 LSY 380
Score = 57.0 bits (136), Expect = 5e-08
Identities = 29/107 (27%), Positives = 53/107 (49%), Gaps = 1/107 (0%)
Query: 506 SWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLH 565
S+ ++ + Y+ + G P+P V +EI+ +R ++W+ N ++ F
Sbjct: 379 SYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFPS 438
Query: 566 TAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNR 612
E + Y +F ++AG + ++IY +PETKGK EI +F R
Sbjct: 439 IQEAIGAY-SFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKR 484
>gi|223029430 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 2 [Homo sapiens]
Length = 445
Score = 121 bits (303), Expect = 2e-27
Identities = 94/330 (28%), Positives = 157/330 (47%), Gaps = 35/330 (10%)
Query: 81 VYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVS-----STVGAAAVSA 135
V++ + LG F FGY S + L+R L D + S T+GAAA
Sbjct: 38 VFLATFAAVLGNFSFGYALVYTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAA-GG 96
Query: 136 LAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVY 195
L+ LN + GR+ +I+ ++ AG A++A A+ LL GR + G G+ + +PVY
Sbjct: 97 LSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVY 156
Query: 196 IAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFG 255
++E++PP +RG L L F S+ A L WR++ P +I
Sbjct: 157 VSEIAPPGVRGALGATPQLMAV----FGSLSLYALGLLLP--WRWLAVAGEAPVLIMILL 210
Query: 256 FLFLPESPRWLIQKGQTQKARRILSQMRGNQT-IDEEYDSIKNNIEEEEKEVGSA---GP 311
F+P SPR+L+ +G+ ++A R L+ +RG + E++ I++N+ + V A P
Sbjct: 211 LSFMPNSPRFLLSRGRDEEALRALAWLRGTDVDVHWEFEQIQDNVRRQSSRVSWAEARAP 270
Query: 312 VICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGV----EDDRLAIWLA 367
+CR P AL+ +++ QQL+GI I+ Y +I + V +DD A
Sbjct: 271 HVCR-----PITVALL----MRLLQQLTGITPILVYLQSIFDSTAVLLPPKDD------A 315
Query: 368 SVTAFTNFIFTLVGVWLVEKVGRRKLTFGS 397
++ + L+ ++ GR+ L F S
Sbjct: 316 AIVGAVRLLSVLIAALTMDLAGRKVLLFVS 345
Score = 67.4 bits (163), Expect = 4e-11
Identities = 33/97 (34%), Positives = 53/97 (54%)
Query: 513 LILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTY 572
++L++ +A G GP+ W + SE+ PL AR + +W+ +++ +FL
Sbjct: 340 VLLFVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGL 399
Query: 573 YGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLF 609
FF +A V L+F C+PETKG+ LE+IES F
Sbjct: 400 QVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFF 436
>gi|47933389 solute carrier family 2, member 9 protein isoform 2
[Homo sapiens]
Length = 511
Score = 115 bits (287), Expect = 2e-25
Identities = 96/339 (28%), Positives = 159/339 (46%), Gaps = 35/339 (10%)
Query: 83 VVAVFSALGG-FLFGYDTGVVSGAMLLLK------------RQLSLDALWQELLVSSTVG 129
V ++ A G FL+GY+ VV+ +K R + D L LL S TV
Sbjct: 29 VASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTL--TLLWSVTVS 86
Query: 130 AAAVSALAGGALNGVFGR---RAAILLASALFTAGSAVLAAANNK----ETLLAGRLVVG 182
A+ L G + + G+ R LLA+ F +A+L A + + E L+ GR ++G
Sbjct: 87 IFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMG 146
Query: 183 LGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDG-WRYM 241
+ G+A +P+Y++E+SP +RG L + +FI G F ++ G L K+ W Y+
Sbjct: 147 IDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLL-GLPELLGKESTWPYL 205
Query: 242 LGLAAVPAVIQFFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIE 300
G+ VPAV+Q FLP+SPR+ L++K +A + G + +E + + +
Sbjct: 206 FGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEV---LA 262
Query: 301 EEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDD 360
E + + +L P R ++ QL G+N I +Y+ +I +G+
Sbjct: 263 ESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPA 322
Query: 361 RLAIWLASVTAFTNFIFTLVGVW---LVEKVGRRKLTFG 396
++ VT T I TL V+ ++E +GRR L G
Sbjct: 323 KIPY----VTLSTGGIETLAAVFSGLVIEHLGRRPLLIG 357
Score = 54.7 bits (130), Expect = 3e-07
Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 1/106 (0%)
Query: 507 WTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHT 566
+ +++G++ + F G G +P+ + E + R + +NW+ N V L F
Sbjct: 384 YLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFI 443
Query: 567 AEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNR 612
+ L Y F ++A G +++Y LPETK + EI F R
Sbjct: 444 QKSLDTY-CFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKR 488
>gi|47933387 solute carrier family 2, member 9 protein isoform 1
[Homo sapiens]
Length = 540
Score = 115 bits (287), Expect = 2e-25
Identities = 96/339 (28%), Positives = 159/339 (46%), Gaps = 35/339 (10%)
Query: 83 VVAVFSALGG-FLFGYDTGVVSGAMLLLK------------RQLSLDALWQELLVSSTVG 129
V ++ A G FL+GY+ VV+ +K R + D L LL S TV
Sbjct: 58 VASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTL--TLLWSVTVS 115
Query: 130 AAAVSALAGGALNGVFGR---RAAILLASALFTAGSAVLAAANNK----ETLLAGRLVVG 182
A+ L G + + G+ R LLA+ F +A+L A + + E L+ GR ++G
Sbjct: 116 IFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMG 175
Query: 183 LGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDG-WRYM 241
+ G+A +P+Y++E+SP +RG L + +FI G F ++ G L K+ W Y+
Sbjct: 176 IDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLL-GLPELLGKESTWPYL 234
Query: 242 LGLAAVPAVIQFFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIE 300
G+ VPAV+Q FLP+SPR+ L++K +A + G + +E + + +
Sbjct: 235 FGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEV---LA 291
Query: 301 EEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDD 360
E + + +L P R ++ QL G+N I +Y+ +I +G+
Sbjct: 292 ESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPA 351
Query: 361 RLAIWLASVTAFTNFIFTLVGVW---LVEKVGRRKLTFG 396
++ VT T I TL V+ ++E +GRR L G
Sbjct: 352 KIPY----VTLSTGGIETLAAVFSGLVIEHLGRRPLLIG 386
Score = 54.7 bits (130), Expect = 3e-07
Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 1/106 (0%)
Query: 507 WTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHT 566
+ +++G++ + F G G +P+ + E + R + +NW+ N V L F
Sbjct: 413 YLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFI 472
Query: 567 AEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNR 612
+ L Y F ++A G +++Y LPETK + EI F R
Sbjct: 473 QKSLDTY-CFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKR 517
>gi|190684655 glucose transporter protein 10 isoform a [Homo
sapiens]
Length = 503
Score = 93.2 bits (230), Expect = 7e-19
Identities = 80/325 (24%), Positives = 140/325 (43%), Gaps = 24/325 (7%)
Query: 91 GGFLFGYDTGVVSGAMLLLKRQLS--------------LDALWQELLVSSTVGAAAVSAL 136
G F FGY+ +++ L ++ + L L L+VS AL
Sbjct: 31 GTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVSLYPLGGLFGAL 90
Query: 137 AGGALNGVFGRRAAILLASALFTAGSAVLAAANNK----ETLLAGRLVVGLGIGIASMTV 192
G L GR+ + LL + +F +A+L + K E ++ GRL+VG+ G++
Sbjct: 91 LAGPLAITLGRKKS-LLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQ 149
Query: 193 PVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQ 252
P+Y+ E +P LRG + + +F G VV W +L VP +Q
Sbjct: 150 PMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLLASCLVPGALQ 209
Query: 253 FFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGP 311
LPESPR+ LI G T+ L ++RG+ + E + ++ EE G
Sbjct: 210 LASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELE---EERAACQGCRAR 266
Query: 312 VICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTA 371
+ + RR + L +L G +++ Y++++ + +GV + ++ + T
Sbjct: 267 RPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQYAIIG-TG 325
Query: 372 FTNFIFTLVGVWLVEKVGRRKLTFG 396
+ +V ++E+VGRR L G
Sbjct: 326 SCELLTAVVSCVVIERVGRRVLLIG 350
Score = 43.9 bits (102), Expect = 5e-04
Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 4/104 (3%)
Query: 505 YSWTALLGLILYLVFFAP-GMGPMPWT--VNSEIYPLWARSTGNACSSGINWIFNVLVSL 561
+ WT L + F G+GP T + +E++ AR + WI +LV L
Sbjct: 372 FPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGL 431
Query: 562 TFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEI 605
F E L+++ + + G G ++ LPETKGK +EI
Sbjct: 432 GFPFIMEALSHF-LYVPFLGVCVCGAIYTGLFLPETKGKTFQEI 474
>gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]
Length = 496
Score = 93.2 bits (230), Expect = 7e-19
Identities = 80/325 (24%), Positives = 140/325 (43%), Gaps = 24/325 (7%)
Query: 91 GGFLFGYDTGVVSGAMLLLKRQLS--------------LDALWQELLVSSTVGAAAVSAL 136
G F FGY+ +++ L ++ + L L L+VS AL
Sbjct: 24 GTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVSLYPLGGLFGAL 83
Query: 137 AGGALNGVFGRRAAILLASALFTAGSAVLAAANNK----ETLLAGRLVVGLGIGIASMTV 192
G L GR+ + LL + +F +A+L + K E ++ GRL+VG+ G++
Sbjct: 84 LAGPLAITLGRKKS-LLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQ 142
Query: 193 PVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQ 252
P+Y+ E +P LRG + + +F G VV W +L VP +Q
Sbjct: 143 PMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLLASCLVPGALQ 202
Query: 253 FFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGP 311
LPESPR+ LI G T+ L ++RG+ + E + ++ EE G
Sbjct: 203 LASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELE---EERAACQGCRAR 259
Query: 312 VICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTA 371
+ + RR + L +L G +++ Y++++ + +GV + ++ + T
Sbjct: 260 RPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQYAIIG-TG 318
Query: 372 FTNFIFTLVGVWLVEKVGRRKLTFG 396
+ +V ++E+VGRR L G
Sbjct: 319 SCELLTAVVSCVVIERVGRRVLLIG 343
Score = 43.9 bits (102), Expect = 5e-04
Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 4/104 (3%)
Query: 505 YSWTALLGLILYLVFFAP-GMGPMPWT--VNSEIYPLWARSTGNACSSGINWIFNVLVSL 561
+ WT L + F G+GP T + +E++ AR + WI +LV L
Sbjct: 365 FPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGL 424
Query: 562 TFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEI 605
F E L+++ + + G G ++ LPETKGK +EI
Sbjct: 425 GFPFIMEALSHF-LYVPFLGVCVCGAIYTGLFLPETKGKTFQEI 467
>gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]
Length = 499
Score = 93.2 bits (230), Expect = 7e-19
Identities = 80/325 (24%), Positives = 140/325 (43%), Gaps = 24/325 (7%)
Query: 91 GGFLFGYDTGVVSGAMLLLKRQLS--------------LDALWQELLVSSTVGAAAVSAL 136
G F FGY+ +++ L ++ + L L L+VS AL
Sbjct: 27 GTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVSLYPLGGLFGAL 86
Query: 137 AGGALNGVFGRRAAILLASALFTAGSAVLAAANNK----ETLLAGRLVVGLGIGIASMTV 192
G L GR+ + LL + +F +A+L + K E ++ GRL+VG+ G++
Sbjct: 87 LAGPLAITLGRKKS-LLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQ 145
Query: 193 PVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQ 252
P+Y+ E +P LRG + + +F G VV W +L VP +Q
Sbjct: 146 PMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLLASCLVPGALQ 205
Query: 253 FFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGP 311
LPESPR+ LI G T+ L ++RG+ + E + ++ EE G
Sbjct: 206 LASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELE---EERAACQGCRAR 262
Query: 312 VICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTA 371
+ + RR + L +L G +++ Y++++ + +GV + ++ + T
Sbjct: 263 RPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQYAIIG-TG 321
Query: 372 FTNFIFTLVGVWLVEKVGRRKLTFG 396
+ +V ++E+VGRR L G
Sbjct: 322 SCELLTAVVSCVVIERVGRRVLLIG 346
Score = 43.9 bits (102), Expect = 5e-04
Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 4/104 (3%)
Query: 505 YSWTALLGLILYLVFFAP-GMGPMPWT--VNSEIYPLWARSTGNACSSGINWIFNVLVSL 561
+ WT L + F G+GP T + +E++ AR + WI +LV L
Sbjct: 368 FPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGL 427
Query: 562 TFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEI 605
F E L+++ + + G G ++ LPETKGK +EI
Sbjct: 428 GFPFIMEALSHF-LYVPFLGVCVCGAIYTGLFLPETKGKTFQEI 470
>gi|207447703 solute carrier family 2 (facilitated glucose/fructose
transporter), member 5 isoform 2 [Homo sapiens]
Length = 244
Score = 65.9 bits (159), Expect = 1e-10
Identities = 53/180 (29%), Positives = 83/180 (46%), Gaps = 32/180 (17%)
Query: 79 AFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKR---------------QLSLDALWQELL 123
A ++A F + F +GY+ V+ LL+++ L LW +
Sbjct: 18 ALATLIAAFGS--SFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWSVTV 75
Query: 124 VSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAA----ANNKETLLAGRL 179
G S L G +N FGR+ A+L + +F+ A+L A + E ++ RL
Sbjct: 76 SMFPFGGFIGSLLVGPLVNK-FGRKGALLFNN-IFSIVPAILMGCSRVATSFELIIISRL 133
Query: 180 VVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASV---------VDGAF 230
+VG+ G++S VP+Y+ E++P NLRG L + LFIT G A + VDG F
Sbjct: 134 LVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGEF 193
>gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens]
Length = 683
Score = 60.5 bits (145), Expect = 5e-09
Identities = 49/200 (24%), Positives = 89/200 (44%), Gaps = 15/200 (7%)
Query: 96 GYDTGVVSGAMLLLKRQLSLDALWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLAS 155
G + VVS A+ ++ + L + + +L A G L GR+ + ++
Sbjct: 123 GVEVFVVSFALPSAEKDMCLSSSKKGMLGMIVYLGMMAGAFILGGLADKLGRKRVLSMSL 182
Query: 156 ALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLF 215
A+ + +++ + L RL+ G+GIG A V Y +E RG ++ +F
Sbjct: 183 AVNASFASLSSFVQGYGAFLFCRLISGIGIGGALPIVFAYFSEFLSREKRGEHLSWLGIF 242
Query: 216 ITGGQFFASVVDGAFSYLQKDGWRYMLG-------------LAAVPAVIQFFGFLFLPES 262
G +AS + A+S + GW + +G + A+P + F+PES
Sbjct: 243 WMTGGLYASAM--AWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPCTVSMVALKFMPES 300
Query: 263 PRWLIQKGQTQKARRILSQM 282
PR+L++ G+ +A IL Q+
Sbjct: 301 PRFLLEMGKHDEAWMILKQV 320
>gi|90669191 solute carrier family 22 member 7 isoform b [Homo
sapiens]
Length = 548
Score = 58.5 bits (140), Expect = 2e-08
Identities = 70/282 (24%), Positives = 123/282 (43%), Gaps = 32/282 (11%)
Query: 133 VSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTV 192
V A+A G L+ FGRR +LL + + T + +AA+ + A + G +A T+
Sbjct: 157 VGAVAFGYLSDRFGRRR-LLLVAYVSTLVLGLASAASVSYVMFAITRTL-TGSALAGFTI 214
Query: 193 PVYIAEVSPPNLRGRLVT--INTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAV 250
V E+ ++ R V +++ F TGG ++V YL +D WR++L +P
Sbjct: 215 IVMPLELEWLDVEHRTVAGVLSSTFWTGGVMLLALV----GYLIRD-WRWLLLAVTLPCA 269
Query: 251 IQFFGFLFLPESPRWLIQKGQTQKARRIL---SQMRGNQTIDEEYDSIKNNIEEEEKEVG 307
++PES RWL+ +G ++A R L +++ G ++ + +E
Sbjct: 270 PGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSF-------SQEAVSKV 322
Query: 308 SAGPVICRMLSY-----PPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRL 362
+AG + R SY P R + + C + F G+N Y + + G+ +
Sbjct: 323 AAGERVVRRPSYLDLFRTPRLRHISLCCVVVWF----GVNFSYYGLSLDVSGLGLNVYQT 378
Query: 363 AIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVA 404
+ +V + + L V GRR G+L GT +A
Sbjct: 379 QLLFGAVELPSKLLVYL----SVRYAGRRLTQAGTLLGTALA 416
>gi|24497497 solute carrier family 22 member 7 isoform a [Homo
sapiens]
Length = 546
Score = 58.5 bits (140), Expect = 2e-08
Identities = 70/282 (24%), Positives = 123/282 (43%), Gaps = 32/282 (11%)
Query: 133 VSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTV 192
V A+A G L+ FGRR +LL + + T + +AA+ + A + G +A T+
Sbjct: 155 VGAVAFGYLSDRFGRRR-LLLVAYVSTLVLGLASAASVSYVMFAITRTL-TGSALAGFTI 212
Query: 193 PVYIAEVSPPNLRGRLVT--INTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAV 250
V E+ ++ R V +++ F TGG ++V YL +D WR++L +P
Sbjct: 213 IVMPLELEWLDVEHRTVAGVLSSTFWTGGVMLLALV----GYLIRD-WRWLLLAVTLPCA 267
Query: 251 IQFFGFLFLPESPRWLIQKGQTQKARRIL---SQMRGNQTIDEEYDSIKNNIEEEEKEVG 307
++PES RWL+ +G ++A R L +++ G ++ + +E
Sbjct: 268 PGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSF-------SQEAVSKV 320
Query: 308 SAGPVICRMLSY-----PPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRL 362
+AG + R SY P R + + C + F G+N Y + + G+ +
Sbjct: 321 AAGERVVRRPSYLDLFRTPRLRHISLCCVVVWF----GVNFSYYGLSLDVSGLGLNVYQT 376
Query: 363 AIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVA 404
+ +V + + L V GRR G+L GT +A
Sbjct: 377 QLLFGAVELPSKLLVYL----SVRYAGRRLTQAGTLLGTALA 414
>gi|24308167 SV2 related protein [Homo sapiens]
Length = 548
Score = 58.5 bits (140), Expect = 2e-08
Identities = 50/166 (30%), Positives = 84/166 (50%), Gaps = 6/166 (3%)
Query: 119 WQELLVSSTVGAAAVSALA-GGALNGVFGRRAAILLASALFTAGSAVLAA-ANNKETLLA 176
WQ L++S V +S+ G ++ +GR+ + + S L+T +L+A A +L
Sbjct: 120 WQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKI-SVLWTLYYGILSAFAPVYSWILV 178
Query: 177 GRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKD 236
R +VG GIG +V +Y AE P R + + + +F G F V+ A +
Sbjct: 179 LRGLVGFGIGGVPQSVTLY-AEFLPMKARAKCILLIEVFWAIGTVFEVVL--AVFVMPSL 235
Query: 237 GWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQM 282
GWR++L L+AVP ++ +LPES R+ + G +KA L ++
Sbjct: 236 GWRWLLILSAVPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRI 281
>gi|24497499 solute carrier family 22 member 8 [Homo sapiens]
Length = 542
Score = 55.8 bits (133), Expect = 1e-07
Identities = 46/188 (24%), Positives = 83/188 (44%), Gaps = 10/188 (5%)
Query: 120 QELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRL 179
+E+ S + + L G L+ FGRR + + L A + A + + R
Sbjct: 122 KEMAQSIFMAGILIGGLVLGDLSDRFGRRPILTCSYLLLAASGSGAAFSPTFPIYMVFRF 181
Query: 180 VVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWR 239
+ G GI +++ + E P +R + T T GQF + A++ Q WR
Sbjct: 182 LCGFGISGITLSTVILNVEWVPTRMRAIMSTALGYCYTFGQFILPGL--AYAIPQ---WR 236
Query: 240 YMLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEE-----YDS 294
++ ++P + F + PES RWL+ G++ KA +IL ++ EE +
Sbjct: 237 WLQLTVSIPFFVFFLSSWWTPESIRWLVLSGKSSKALKILRRVAVFNGKKEEGERLSLEE 296
Query: 295 IKNNIEEE 302
+K N+++E
Sbjct: 297 LKLNLQKE 304
>gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens]
Length = 727
Score = 55.5 bits (132), Expect = 2e-07
Identities = 46/158 (29%), Positives = 70/158 (44%), Gaps = 11/158 (6%)
Query: 133 VSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTV 192
V A G L GR+ ++L+ ++ + + + L RL+ G GIG A TV
Sbjct: 203 VGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLFCRLLSGFGIGGAIPTV 262
Query: 193 PVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAF-----------SYLQKDGWRYM 241
Y AEV RG ++ +F G +AS + A S Q WR
Sbjct: 263 FSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVF 322
Query: 242 LGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRIL 279
+ + A+P V F+PESPR+L++ G+ +A IL
Sbjct: 323 VIVCALPCVSSVVALTFMPESPRFLLEVGKHDEAWMIL 360
>gi|63999576 solute carrier family 22, member 17 isoform b [Homo
sapiens]
Length = 520
Score = 54.7 bits (130), Expect = 3e-07
Identities = 74/276 (26%), Positives = 119/276 (43%), Gaps = 30/276 (10%)
Query: 145 FGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNL 204
FGRR +LL L AAA + ++A R ++G + + V + E+ P
Sbjct: 125 FGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQ 184
Query: 205 RGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVI-QFFGF--LFLPE 261
R R+ L GG F + + KD WR++ + P ++ F+G+ LFL E
Sbjct: 185 RLRVALAGELVGVGGHFLFL----GLALVSKD-WRFLQRMITAPCILFLFYGWPGLFL-E 238
Query: 262 SPRWLIQKGQTQKAR---RILSQMR--GNQTIDEEYDSIKNNIEEEEKEVGSAGPVICRM 316
S RWLI K Q ++A+ RIL++ Q + EE ++E ++ +
Sbjct: 239 SARWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASL 298
Query: 317 LSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSG----VEDDRLAIWLASVTAF 372
L+Y + L++ L N I + Q G D L LAS TA
Sbjct: 299 LNYRNIWKNLLI---------LGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAA 349
Query: 373 TNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIIL 408
+F +GV V++ GRR + S+ T +A ++L
Sbjct: 350 LACVF--LGV-TVDRFGRRGILLLSMTLTGIASLVL 382
>gi|21361834 solute carrier family 22, member 17 isoform a [Homo
sapiens]
Length = 538
Score = 54.7 bits (130), Expect = 3e-07
Identities = 74/276 (26%), Positives = 119/276 (43%), Gaps = 30/276 (10%)
Query: 145 FGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNL 204
FGRR +LL L AAA + ++A R ++G + + V + E+ P
Sbjct: 125 FGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQ 184
Query: 205 RGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVI-QFFGF--LFLPE 261
R R+ L GG F + + KD WR++ + P ++ F+G+ LFL E
Sbjct: 185 RLRVALAGELVGVGGHFLFL----GLALVSKD-WRFLQRMITAPCILFLFYGWPGLFL-E 238
Query: 262 SPRWLIQKGQTQKAR---RILSQMR--GNQTIDEEYDSIKNNIEEEEKEVGSAGPVICRM 316
S RWLI K Q ++A+ RIL++ Q + EE ++E ++ +
Sbjct: 239 SARWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASL 298
Query: 317 LSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSG----VEDDRLAIWLASVTAF 372
L+Y + L++ L N I + Q G D L LAS TA
Sbjct: 299 LNYRNIWKNLLI---------LGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAA 349
Query: 373 TNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIIL 408
+F +GV V++ GRR + S+ T +A ++L
Sbjct: 350 LACVF--LGV-TVDRFGRRGILLLSMTLTGIASLVL 382
>gi|4507005 solute carrier family 22 member 5 [Homo sapiens]
Length = 557
Score = 54.3 bits (129), Expect = 3e-07
Identities = 48/193 (24%), Positives = 90/193 (46%), Gaps = 8/193 (4%)
Query: 88 SALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQE-LLVSSTVGAAAVSALAGGALNGVFG 146
S L G+ F D + + ++ + L + W+ L +S + + G L+ FG
Sbjct: 112 SCLDGWEFSQDVYL---STIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFG 168
Query: 147 RRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRG 206
R+ + + + T S + + N E + ++VG+G + V E+ ++R
Sbjct: 169 RKNVLFVTMGMQTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVR- 227
Query: 207 RLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWL 266
+ +TL + F +V F+Y +D WR +L +P V+ + F+PESPRWL
Sbjct: 228 --IIFSTLGVCIFYAFGYMVLPLFAYFIRD-WRMLLVALTMPGVLCVALWWFIPESPRWL 284
Query: 267 IQKGQTQKARRIL 279
I +G+ ++A I+
Sbjct: 285 ISQGRFEEAEVII 297
>gi|166064021 solute carrier family 22 (organic anion transporter),
member 13 [Homo sapiens]
Length = 551
Score = 53.9 bits (128), Expect = 4e-07
Identities = 65/285 (22%), Positives = 117/285 (41%), Gaps = 35/285 (12%)
Query: 133 VSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTV 192
V L G L GR+A IL LFT A + E +A R V + S +
Sbjct: 150 VGTLMFGPLCDRIGRKATILAQLLLFTLIGLATAFVPSFELYMALRFAVATAVAGLSFSN 209
Query: 193 PVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQ 252
+ E P+ R + V + + GQ + + F WR + P ++
Sbjct: 210 VTLLTEWVGPSWRTQAVVLAQCNFSLGQMVLAGLAYGFR-----NWRLLQITGTAPGLLL 264
Query: 253 FFGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGPV 312
FF F LPES RWL+ +G+ +A +++ + + + + E+ G+A
Sbjct: 265 FFYFWALPESARWLLTRGRMDEAIQLIQKAASVNRRKLSPELMNQLVPEKTGPSGNA--- 321
Query: 313 ICRMLSYPPTRR-ALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTA 371
+ +P R+ LI+ C + ++++ YY ++ V D L ++L
Sbjct: 322 -LDLFRHPQLRKVTLIIFC-------VWFVDSLGYYGLSL----QVGDFGLDVYL----- 364
Query: 372 FTNFIFTLV-------GVWLVEKVGRRKLTFGSLA-GTTVALIIL 408
T IF V ++++++ GR+ G+L G + +II+
Sbjct: 365 -TQLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLVLGGLMCIIII 408
>gi|213021148 SVOP-like isoform 1 [Homo sapiens]
Length = 492
Score = 53.1 bits (126), Expect = 8e-07
Identities = 46/166 (27%), Positives = 82/166 (49%), Gaps = 6/166 (3%)
Query: 119 WQELLVSSTVGAA-AVSALAGGALNGVFGRRAAILLASALFTAGSAVLAA-ANNKETLLA 176
WQ LV++ V V ++ G L +GR ILL S L+ A ++L + A + +
Sbjct: 84 WQVALVTTMVFFGYMVFSILFGLLADRYGRWK-ILLISFLWGAYFSLLTSFAPSYIWFVF 142
Query: 177 GRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKD 236
R +VG G+ S + + E P RG ++ ++ +F G ++ A +
Sbjct: 143 LRTMVGCGVSGHSQGL-IIKTEFLPTKYRGYMLPLSQVFWLAGSLL--IIGLASVIIPTI 199
Query: 237 GWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQM 282
GWR+++ +A++P +I F F+PES R+ + G T+ A L ++
Sbjct: 200 GWRWLIRVASIPGIILIVAFKFIPESARFNVSTGNTRAALATLERV 245
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,435,815
Number of Sequences: 37866
Number of extensions: 1008164
Number of successful extensions: 3496
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 3305
Number of HSP's gapped (non-prelim): 146
length of query: 648
length of database: 18,247,518
effective HSP length: 109
effective length of query: 539
effective length of database: 14,120,124
effective search space: 7610746836
effective search space used: 7610746836
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.