Search of human proteins with 203098753

Search of human proteins with 203098753

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|203098753 pyruvate dehydrogenase complex, component X
isoform 1 [Homo sapiens]
         (501 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|203098753 pyruvate dehydrogenase complex, component X isoform...   994   0.0  
gi|203098816 pyruvate dehydrogenase complex, component X isoform...   879   0.0  
gi|31711992 dihydrolipoamide S-acetyltransferase [Homo sapiens]       315   6e-86
gi|110671329 dihydrolipoamide branched chain transacylase precur...   150   2e-36
gi|19923748 dihydrolipoamide S-succinyltransferase (E2 component...   139   8e-33
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]       43   6e-04
gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens]       43   6e-04
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    42   0.001
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    40   0.005
gi|116256464 hypothetical protein LOC343990 [Homo sapiens]             40   0.005
gi|9945318 MAX binding protein [Homo sapiens]                          40   0.006
gi|163965366 nascent polypeptide-associated complex alpha subuni...    40   0.006
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    40   0.006
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]      39   0.011
gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog ...    39   0.014
gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog ...    39   0.014
gi|116284392 mucin 2 precursor [Homo sapiens]                          38   0.019
gi|110349719 titin isoform N2-A [Homo sapiens]                         38   0.025
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ...    38   0.025
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [...    38   0.025
gi|47132519 Ras association and pleckstrin homology domains 1 is...    38   0.025
gi|41281612 zinc finger protein 828 [Homo sapiens]                     38   0.025
gi|40807465 zinc finger protein 341 [Homo sapiens]                     38   0.025
gi|50345997 E1A binding protein p300 [Homo sapiens]                    37   0.032
gi|7706469 Kruppel-like factor [Homo sapiens]                          37   0.032
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]             37   0.032
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]              37   0.032
gi|150170670 piccolo isoform 2 [Homo sapiens]                          37   0.032
gi|150378539 piccolo isoform 1 [Homo sapiens]                          37   0.032
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         37   0.032

>gi|203098753 pyruvate dehydrogenase complex, component X isoform 1
           [Homo sapiens]
          Length = 501

 Score =  994 bits (2570), Expect = 0.0
 Identities = 501/501 (100%), Positives = 501/501 (100%)

Query: 1   MAASWRLGCDPRLLRYLVGFPGRRSVGLVKGALGWSVSRGANWRWFHSTQWLRGDPIKIL 60
           MAASWRLGCDPRLLRYLVGFPGRRSVGLVKGALGWSVSRGANWRWFHSTQWLRGDPIKIL
Sbjct: 1   MAASWRLGCDPRLLRYLVGFPGRRSVGLVKGALGWSVSRGANWRWFHSTQWLRGDPIKIL 60

Query: 61  MPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVEEGSK 120
           MPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVEEGSK
Sbjct: 61  MPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVEEGSK 120

Query: 121 NIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTL 180
           NIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTL
Sbjct: 121 NIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTL 180

Query: 181 RFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTAT 240
           RFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTAT
Sbjct: 181 RFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTAT 240

Query: 241 PTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVPH 300
           PTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVPH
Sbjct: 241 PTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVPH 300

Query: 301 AYATADCDLGAVLKVRQDLVKDDIKVSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPF 360
           AYATADCDLGAVLKVRQDLVKDDIKVSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPF
Sbjct: 301 AYATADCDLGAVLKVRQDLVKDDIKVSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPF 360

Query: 361 IDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNL 420
           IDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNL
Sbjct: 361 IDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNL 420

Query: 421 GMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDD 480
           GMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDD
Sbjct: 421 GMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDD 480

Query: 481 ELATRFLKSFKANLENPIRLA 501
           ELATRFLKSFKANLENPIRLA
Sbjct: 481 ELATRFLKSFKANLENPIRLA 501


>gi|203098816 pyruvate dehydrogenase complex, component X isoform 2
           [Homo sapiens]
          Length = 486

 Score =  879 bits (2271), Expect = 0.0
 Identities = 448/448 (100%), Positives = 448/448 (100%)

Query: 54  GDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKI 113
           GDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKI
Sbjct: 39  GDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKI 98

Query: 114 VVEEGSKNIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKK 173
           VVEEGSKNIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKK
Sbjct: 99  VVEEGSKNIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKK 158

Query: 174 EHIPGTLRFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRP 233
           EHIPGTLRFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRP
Sbjct: 159 EHIPGTLRFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRP 218

Query: 234 TPAPTATPTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTE 293
           TPAPTATPTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTE
Sbjct: 219 TPAPTATPTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTE 278

Query: 294 SKSTVPHAYATADCDLGAVLKVRQDLVKDDIKVSVNDFIIKAAAVTLKQMPDVNVSWDGE 353
           SKSTVPHAYATADCDLGAVLKVRQDLVKDDIKVSVNDFIIKAAAVTLKQMPDVNVSWDGE
Sbjct: 279 SKSTVPHAYATADCDLGAVLKVRQDLVKDDIKVSVNDFIIKAAAVTLKQMPDVNVSWDGE 338

Query: 354 GPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGG 413
           GPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGG
Sbjct: 339 GPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGG 398

Query: 414 SFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSS 473
           SFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSS
Sbjct: 399 SFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSS 458

Query: 474 DSRVVDDELATRFLKSFKANLENPIRLA 501
           DSRVVDDELATRFLKSFKANLENPIRLA
Sbjct: 459 DSRVVDDELATRFLKSFKANLENPIRLA 486


>gi|31711992 dihydrolipoamide S-acetyltransferase [Homo sapiens]
          Length = 647

 Score =  315 bits (807), Expect = 6e-86
 Identities = 189/460 (41%), Positives = 269/460 (58%), Gaps = 49/460 (10%)

Query: 57  IKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVE 116
           +++L+P+LSPTM  G + +W KK GE +S GD L EIETDKA +  +  ++G LAKI+V 
Sbjct: 219 MQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVP 278

Query: 117 EGSKNIRLGSLIGLIVEEGED------WKHVEIPKDVGP--PPPVSKPSEPRPSPEPQIS 168
           EG++++ LG+ + +IVE+  D      ++  E+  D+ P  PPP   P    P P PQ  
Sbjct: 279 EGTRDVPLGTPLCIIVEKEADISAFADYRPTEVT-DLKPQVPPPTPPPVAAVP-PTPQPL 336

Query: 169 IPVKKEHIPGTL-----RFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLK 223
            P      P T      R  +SP A+ +  +  +D +Q   TGP G  TK+D    V   
Sbjct: 337 APTPSAPCPATPAGPKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVP-- 394

Query: 224 QTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNI 283
                  S+  PAP A                   V+PP      P   G FT+IP SNI
Sbjct: 395 -------SKVAPAPAA-------------------VVPPTGPGMAPVPTGVFTDIPISNI 428

Query: 284 RRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVK---DDIKVSVNDFIIKAAAVTL 340
           RRVIA+RL +SK T+PH Y + D ++G VL VR++L K      K+SVNDFIIKA+A+  
Sbjct: 429 RRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRSKISVNDFIIKASALAC 488

Query: 341 KQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKA 400
            ++P+ N SW     +Q   +D+SVAV+T  GL+TPI+ +A  KG++ IA+ V +L+ KA
Sbjct: 489 LKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKA 548

Query: 401 RDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAK 460
           R+GKL P E+QGG+F+ISNLGMFGI  F+A+INPPQACILA+G     L   ++E+G   
Sbjct: 549 REGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLVPADNEKG--- 605

Query: 461 LQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENPIRL 500
                +++VT+S D RVVD  +  ++L  F+  LE PI +
Sbjct: 606 FDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITM 645



 Score = 95.9 bits (237), Expect = 8e-20
 Identities = 98/352 (27%), Positives = 144/352 (40%), Gaps = 76/352 (21%)

Query: 21  PGRRS-----VGLVKGALGWSVSRGANWRWFHSTQWLRGDP----------IKILMPSLS 65
           P RR+      G V+   GW+ S GA  R     Q L G P           K+ +PSLS
Sbjct: 42  PARRNSVTTGYGGVRALCGWTPSSGATPRNRLLLQLL-GSPGRRYYSLPPHQKVPLPSLS 100

Query: 66  PTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVEEGSKNIRLG 125
           PTM+ G I +W KKEG+ ++ GD + E+ETDKA V  ++ ++  +AKI+V EG++++ +G
Sbjct: 101 PTMQAGTIARWEKKEGDKINEGDLIAEVETDKATVGFESLEECYMAKILVAEGTRDVPIG 160

Query: 126 SLIGLIVEEGED---WKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGT--- 179
           ++I + V + ED   +K+  +     P P  +    P P+P    S P      PG+   
Sbjct: 161 AIICITVGKPEDIEAFKNYTLDSSAAPTPQAA----PAPTPAATASPPTPSAQAPGSSYP 216

Query: 180 -----LRFRLSPA---------ARNILEKHS---------------------------LD 198
                L   LSP           + + EK S                           + 
Sbjct: 217 PHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKIL 276

Query: 199 ASQGTATGPRG-----IFTKEDALKLVQLKQTGKITESRP-TPAPTATPTAPSPLQATAG 252
             +GT   P G     I  KE  +      +  ++T+ +P  P PT  P A  P   T  
Sbjct: 277 VPEGTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVP--PTPQ 334

Query: 253 PSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVPHAYAT 304
           P  P P  P  +TP  P     F    A  +       LT+ K T P    T
Sbjct: 335 PLAPTPSAPCPATPAGPKG-RVFVSPLAKKLAVEKGIDLTQVKGTGPDGRIT 385


>gi|110671329 dihydrolipoamide branched chain transacylase precursor
           [Homo sapiens]
          Length = 482

 Score =  150 bits (380), Expect = 2e-36
 Identities = 121/457 (26%), Positives = 214/457 (46%), Gaps = 45/457 (9%)

Query: 48  STQWLRGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDD 107
           +T  LRG  ++  +  +   + E  + +W  KEG+ VS  D++CE+++DKA VT+ +  D
Sbjct: 56  TTAALRGQVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYD 115

Query: 108 GILAKIVVEEGSKNIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQI 167
           G++ K+       N+   + +G  + + E     +  +DV   P VS             
Sbjct: 116 GVIKKLYY-----NLDDIAYVGKPLVDIETEALKDSEEDVVETPAVSHDEHTH------- 163

Query: 168 SIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGK 227
                 + I G  +   +PA R +  ++++  S+   +G  G   KED L  ++ KQTG 
Sbjct: 164 ------QEIKGR-KTLATPAVRRLAMENNIKLSEVVGSGKDGRILKEDILNYLE-KQTGA 215

Query: 228 ITESRPTPAPTATPTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVI 287
           I    P+P     P  P P   T           P+     P   G     P    ++ +
Sbjct: 216 ILP--PSPKVEIMPPPPKPKDMTV----------PILVSKPPVFTGKDKTEPIKGFQKAM 263

Query: 288 AKRLTESKSTVPHAYATADCDLGAVLKVRQDL----VKDDIKVSVNDFIIKAAAVTLKQM 343
            K ++ +   +PH     + DL  ++K+R++L        IK+S   F +KAA++ L Q 
Sbjct: 264 VKTMSAALK-IPHFGYCDEIDLTELVKLREELKPIAFARGIKLSFMPFFLKAASLGLLQF 322

Query: 344 PDVNVSWDGEGPKQLPFI---DISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKA 400
           P +N S D E  + + +    +I +A+ T++GL+ P +K+     I +IA  +  L K  
Sbjct: 323 PILNASVD-ENCQNITYKASHNIGIAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLG 381

Query: 401 RDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAK 460
              +L   +  GG+F++SN+G  G      VI PP+  I A+G  + + +  +  E    
Sbjct: 382 SVSQLSTTDLTGGTFTLSNIGSIGGTFAKPVIMPPEVAIGALGSIKAIPRFNQKGE---- 437

Query: 461 LQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 497
           + + Q++ V+ S+D RV+D    +RF   +K+ LENP
Sbjct: 438 VYKAQIMNVSWSADHRVIDGATMSRFSNLWKSYLENP 474


>gi|19923748 dihydrolipoamide S-succinyltransferase (E2 component of
           2-oxo-glutarate complex) [Homo sapiens]
          Length = 453

 Score =  139 bits (349), Expect = 8e-33
 Identities = 125/468 (26%), Positives = 210/468 (44%), Gaps = 93/468 (19%)

Query: 44  RWFHSTQWLRGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLD 103
           R+F +T   + D + +  P+ + ++ EG+ V+W K  G+ V+  + +CEIETDK  V + 
Sbjct: 58  RFFRTTAVCKDDLVTVKTPAFAESVTEGD-VRWEKAVGDTVAEDEVVCEIETDKTSVQVP 116

Query: 104 ASDDGILAKIVVEEGSKNIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSE----P 159
           +  +G++  ++V +G K           VE G     +   +  G  P  +KP+E     
Sbjct: 117 SPANGVIEALLVPDGGK-----------VEGGTP---LFTLRKTGAAPAKAKPAEAPAAA 162

Query: 160 RPSPEP-QISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALK 218
            P  EP   ++P     IP  +    SP+                               
Sbjct: 163 APKAEPTAAAVPPPAAPIPTQMPPVPSPSQ------------------------------ 192

Query: 219 LVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEI 278
                 +GK       P     PT   PL                + PG    + +    
Sbjct: 193 ----PPSGK-------PVSAVKPTVAPPL----------------AEPGAGKGLRSEHRE 225

Query: 279 PASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQD-----LVKDDIKVSVNDFII 333
             + +R+ IA+RL E+++T        + D+  + ++R       L K ++K+      +
Sbjct: 226 KMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFV 285

Query: 334 KAAAVTLKQMPDVNVSWDGEGPKQL--PFIDISVAVATDKGLLTPIIKDAAAKGIQEIAD 391
           KA+A  L++ P VN   D    + +   +IDISVAVAT +GL+ P+I++  A    +I  
Sbjct: 286 KASAFALQEQPVVNAVIDDTTKEVVYRDYIDISVAVATPRGLVVPVIRNVEAMNFADIER 345

Query: 392 SVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAV-GRF-RPVL 449
           ++  L +KAR  +L  E+  GG+F+ISN G+FG    T +INPPQ+ IL + G F RPV 
Sbjct: 346 TITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHGIFDRPVA 405

Query: 450 KLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 497
                     K++ R ++ V ++ D R++D   A  FL+  KA +E+P
Sbjct: 406 I-------GGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDP 446


>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
          Length = 2240

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 43/171 (25%), Positives = 64/171 (37%), Gaps = 14/171 (8%)

Query: 137 DWKHVEIPKDVGPPPPVSKPS--EPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEK 194
           ++  V+  K   P P +   S  E R S E   ++   K+  P        PA RN++ K
Sbjct: 510 NYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPRNLVPK 569

Query: 195 HSLDASQGTAT--------GPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSP 246
            S  A+   AT        G +G   K   L            ++ P PA     +   P
Sbjct: 570 KSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAASKKFP 629

Query: 247 LQATAGPSYPRPVIPPV----STPGQPNAVGTFTEIPASNIRRVIAKRLTE 293
             A    +  +PV+P V      PG+  A+      P S IR+ I + L E
Sbjct: 630 GSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKE 680


>gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens]
          Length = 1189

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 43/171 (25%), Positives = 64/171 (37%), Gaps = 14/171 (8%)

Query: 137 DWKHVEIPKDVGPPPPVSKPS--EPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEK 194
           ++  V+  K   P P +   S  E R S E   ++   K+  P        PA RN++ K
Sbjct: 510 NYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPRNLVPK 569

Query: 195 HSLDASQGTAT--------GPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSP 246
            S  A+   AT        G +G   K   L            ++ P PA     +   P
Sbjct: 570 KSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAASKKFP 629

Query: 247 LQATAGPSYPRPVIPPV----STPGQPNAVGTFTEIPASNIRRVIAKRLTE 293
             A    +  +PV+P V      PG+  A+      P S IR+ I + L E
Sbjct: 630 GSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKE 680


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 43/151 (28%), Positives = 62/151 (41%), Gaps = 26/151 (17%)

Query: 111  AKIVVEEGSKNIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSEPR-PSPEPQISI 169
            A + V   S   R G L+     EGE       P+  G  PP   P+ P  P P P ++ 
Sbjct: 1094 AAMYVPARSGRGRKGPLVKQTKVEGE-------PQKGGGLPPAPSPTSPASPQPPPAVAA 1146

Query: 170  PVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQT---- 225
            P +K  IP       +P+  +     S  +SQG++T         +A    Q + T    
Sbjct: 1147 PSEKNSIPIPTIIIKAPSTSS-----SGRSSQGSST---------EAEPPTQPEPTGGGG 1192

Query: 226  GKITESRPTPAPTATPTAPSPLQATAGPSYP 256
            G  +   P PA +  P +PSP+   A PS P
Sbjct: 1193 GGGSSPSPAPAMSPVPPSPSPVPTPASPSGP 1223



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 36/160 (22%), Positives = 55/160 (34%), Gaps = 8/160 (5%)

Query: 140  HVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDA 199
            HV   ++  P  PV+    P     P +  P  +  +P       SP +    E++ L  
Sbjct: 1491 HVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPP------SPTSPRASEENGLPL 1544

Query: 200  SQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPV 259
                   P       + L +  L    + + S   P    TP  P PL  T  P+ P P 
Sbjct: 1545 LVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPP 1604

Query: 260  IPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVP 299
            +PP +    P  + +      S    V    LT+  S  P
Sbjct: 1605 VPPPAVAAAPPTLDSTASSLTSYDSEVAT--LTQGASAAP 1642


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 4/112 (3%)

Query: 140 HVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKE--HIPGTLRFRLSPAARNILEKHSL 197
           H++I + V  PPP+  P  P P P P    P + E   +  T    L   A  +      
Sbjct: 658 HLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKA 717

Query: 198 DAS-QGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQ 248
           + S  G      G  T+   L+ +Q  QT  + ++ P P P   P  PSP Q
Sbjct: 718 EVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQP-PPSPQQ 768



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 38/144 (26%), Positives = 51/144 (35%), Gaps = 22/144 (15%)

Query: 144 PKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGT 203
           P    PPPP+  P  P  SP P  S P               P A+   E+        T
Sbjct: 419 PPSTSPPPPLCPPPPPPVSPPPLPSPP--------------PPPAQEEQEESPPPVVPAT 464

Query: 204 ATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPVIPPV 263
            +  RG          +   Q  +   +R  P  T+ PT P+P  AT GP    P + P 
Sbjct: 465 CSRKRG-------RPPLTPSQRAEREAARAGPEGTSPPT-PTPSTATGGPPEDSPTVAPK 516

Query: 264 STPGQPNAVGTFTEIPASNIRRVI 287
           ST    N       + ++   RVI
Sbjct: 517 STTFLKNIRQFIMPVVSARSSRVI 540



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 41/152 (26%), Positives = 52/152 (34%), Gaps = 30/152 (19%)

Query: 141 VEIPKDVGPP----PPVSKPSEPRPSPEPQ---------ISIPVKKEHIPGTLRFRLSPA 187
           VE+   + PP    PPV  P EP P P P          + +P K+  I     FR +  
Sbjct: 557 VEVSPVLRPPITTSPPV--PQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSL 614

Query: 188 ARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTG------KITESRPTPAPTATP 241
            R +             + P    T      L++  Q        KI ES  TP P   P
Sbjct: 615 TRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAP 674

Query: 242 TAPSPLQATAGPSYPRPVIPPVSTPGQPNAVG 273
            AP P    A  S   P         +P AVG
Sbjct: 675 EAPEPEPPPADDSPAEP---------EPRAVG 697



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 17/42 (40%), Positives = 18/42 (42%), Gaps = 2/42 (4%)

Query: 230 ESRPTPAPTATPTAPSPLQATAGPSY--PRPVIPPVSTPGQP 269
           E    P P  TP APSP      PS   P P+ PP   P  P
Sbjct: 397 EEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSP 438


>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
          Length = 962

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 39/146 (26%), Positives = 55/146 (37%), Gaps = 18/146 (12%)

Query: 78  KKEGEAVSAGDALCEIETDKAVVTLDASDD--GILAKIVVEEGSKNIRLGSLIGLIVEEG 135
           K++GEA  AG   C   TDKA   + A +D        + E  +                
Sbjct: 370 KQDGEAPPAGP--CAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSA 427

Query: 136 EDWKHVEIPKDVGPPPPVSKPSE---PRPSPEPQISIPVKKEHIPGTLRFRLS------- 185
            D     +PK+  P PPV    E   P P+PEP+     + E   GT   R+        
Sbjct: 428 RDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAP 487

Query: 186 ----PAARNILEKHSLDASQGTATGP 207
               PA ++ L+     AS+G A  P
Sbjct: 488 APSPPAPKSCLKHRPAAASEGPAASP 513


>gi|9945318 MAX binding protein [Homo sapiens]
          Length = 582

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 41/156 (26%), Positives = 57/156 (36%), Gaps = 14/156 (8%)

Query: 141 VEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIP------GTLRFRLSPAARNILEK 194
           VE P+   PP P+S P+ P P+P P ++ P     IP              P      + 
Sbjct: 55  VEEPRMEAPPLPLSPPAPP-PAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQP 113

Query: 195 HSLDASQGTATGPRGIFTKEDALKLVQLKQTGK----ITESRPTPAPTATPTAPSPLQAT 250
             L   Q    G  G+  KE A  L    Q       + +S+ T  P  +P    PL   
Sbjct: 114 LPLAPRQPALVGAPGLSIKEPA-PLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTP 172

Query: 251 AGPSYPRPVIPPVSTPGQ--PNAVGTFTEIPASNIR 284
                P P + P   P Q  P  +GT    PA  ++
Sbjct: 173 VLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVK 208


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 40/136 (29%), Positives = 49/136 (36%), Gaps = 10/136 (7%)

Query: 139  KHVEIPKDVGPPPPVSKPSEPRP--SPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHS 196
            K    P    PP P   P+ P P  +P P    P   +  P    F    +        S
Sbjct: 983  KGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPS 1042

Query: 197  LDASQGTATGPRGIFTKEDALKLVQLKQTGKITES---RPTPAPTATPTAPSPLQATAGP 253
               S      P+G  T   A   +   + G  T S    PTP P ATP  PSP    A P
Sbjct: 1043 PKGSPAATPLPKGAPTTPAAT--LPSPKGGPATPSLKGAPTP-PAATP--PSPKGGPATP 1097

Query: 254  SYPRPVIPPVSTPGQP 269
            S     +PP +TP  P
Sbjct: 1098 SPKGAPMPPAATPPSP 1113



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 38/138 (27%), Positives = 55/138 (39%), Gaps = 20/138 (14%)

Query: 144  PKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGT 203
            P  + P   +  P+   PSP+   +IP  KE          +PA  +     S +AS   
Sbjct: 1539 PATLAPKEALIPPAMTVPSPKKTPAIPTPKE----------APATPS-----SKEASSPP 1583

Query: 204  ATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPVIPPV 263
            A  P    T + A    +L     +T   P+P    TP A +P     GP+ P P   P 
Sbjct: 1584 AVTPS---TYKGAPSPKELLIPPAVTS--PSPKEAPTPPAVTPPSPEKGPATPAPKGTPT 1638

Query: 264  STPGQPNAVGTFTEIPAS 281
            S P  P+++      PAS
Sbjct: 1639 SPPVTPSSLKDSPTSPAS 1656



 Score = 37.7 bits (86), Expect = 0.025
 Identities = 37/159 (23%), Positives = 62/159 (38%), Gaps = 8/159 (5%)

Query: 138  WKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSL 197
            +K    PK++  PP V+ PS P+ +P P    P   E  P T   + +P +  +      
Sbjct: 1590 YKGAPSPKELLIPPAVTSPS-PKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLK 1648

Query: 198  DA--SQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPL----QATA 251
            D+  S  + T   G    + +  L   K    + E    PAP +TP   +P     Q   
Sbjct: 1649 DSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKK 1708

Query: 252  GPSYPRPVIP-PVSTPGQPNAVGTFTEIPASNIRRVIAK 289
              +   P+ P P +  G    + T    P   +++  +K
Sbjct: 1709 SSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK 1747



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 38/144 (26%), Positives = 48/144 (33%), Gaps = 26/144 (18%)

Query: 139  KHVEIPKDVGPPPPVSKPSEPRP--SPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHS 196
            K    P    PP P   P+ P P  +P P  + P   +  P T   + +P    +    S
Sbjct: 960  KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP-S 1018

Query: 197  LDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATP-----------TAPS 245
               S      P+G  T   A            T   P  +P ATP           T PS
Sbjct: 1019 PKGSPAATPFPKGASTPPAA------------TPPSPKGSPAATPLPKGAPTTPAATLPS 1066

Query: 246  PLQATAGPSYPRPVIPPVSTPGQP 269
            P    A PS      PP +TP  P
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSP 1090



 Score = 36.6 bits (83), Expect = 0.055
 Identities = 36/148 (24%), Positives = 47/148 (31%), Gaps = 8/148 (5%)

Query: 139  KHVEIPKDVGPPPPVSKPSEPRPSPEPQISI----PVKKEHIPGTLRFRLSPAARNILEK 194
            K    P  V  P P   P+ P P   P +S+    P K    P       SP+ +     
Sbjct: 883  KETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP 942

Query: 195  HSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPS 254
             +         GP     K           + K   + P+P    TP A +P     GP+
Sbjct: 943  PAATPPSPKG-GPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPA 1001

Query: 255  YPRPV---IPPVSTPGQPNAVGTFTEIP 279
             P P     PP  TP  P      T  P
Sbjct: 1002 TPSPKGAPTPPAVTPPSPKGSPAATPFP 1029



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 38/147 (25%), Positives = 50/147 (34%), Gaps = 36/147 (24%)

Query: 139  KHVEIPKDVGPPPPVSKPSEPRP--SPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHS 196
            K    P    PP P   P+ P P  +P P  + P   +  P T   + +P          
Sbjct: 937  KGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP-------- 988

Query: 197  LDASQGTATGPRGIFTKEDALKLVQLKQTGKITES---RPTPAPTATPTAPSPLQATAGP 253
                  T   P+G                G  T S    PTP P  TP  PSP  + A  
Sbjct: 989  ---PAATPPSPKG----------------GPATPSPKGAPTP-PAVTP--PSPKGSPAAT 1026

Query: 254  SYPRPV-IPPVSTPGQPNAVGTFTEIP 279
             +P+    PP +TP  P      T +P
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLP 1053



 Score = 32.7 bits (73), Expect = 0.79
 Identities = 30/128 (23%), Positives = 44/128 (34%), Gaps = 26/128 (20%)

Query: 156 PSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATGPRGIFTKED 215
           P  P+ +P P    P+  + +    +   +P+  N+       A+      P    T   
Sbjct: 858 PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSS 917

Query: 216 ALKLVQLKQTGKITESRPTPAPTATPTAPSPLQA-----------TAGPSYPRP---VIP 261
             K            +R TPAP   P +PSP  A             GP+ P P     P
Sbjct: 918 PKK------------ARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP 965

Query: 262 PVSTPGQP 269
           P +TP  P
Sbjct: 966 PAATPPSP 973



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 37/124 (29%), Positives = 44/124 (35%), Gaps = 19/124 (15%)

Query: 150  PPPVSKPSEPR---PSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATG 206
            PPP   P+ P    PSP+  ++ P  K   P T      PAA     K  L         
Sbjct: 1143 PPPKGAPTTPAATPPSPKGGLATPPPKG-APTT------PAATPPSPKGGL-----ATPS 1190

Query: 207  PRGIFTKEDALKLVQLKQTGKITESRPTPAPTA-TPTAPSPLQATAGPSYPRPVIPPVST 265
            P+G  T   A         G +    P  APT    T PSP    A PS       P +T
Sbjct: 1191 PKGAPTTPAA---TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1247

Query: 266  PGQP 269
            P  P
Sbjct: 1248 PPSP 1251



 Score = 29.3 bits (64), Expect = 8.7
 Identities = 36/121 (29%), Positives = 43/121 (35%), Gaps = 19/121 (15%)

Query: 150  PPPVSKPSEPR---PSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATG 206
            PPP   P+ P    PSP+  ++ P  K   P T      PAA     K  L         
Sbjct: 1166 PPPKGAPTTPAATPPSPKGGLATPSPKG-APTT------PAATPPSPKGGL-----ATPS 1213

Query: 207  PRGIFTKEDALKLVQLKQTGKITESRPTPAPTA-TPTAPSPLQATAGPSYPRPVIPPVST 265
            P+G  T   A         G +    P  APT    T PSP    A P       PP +T
Sbjct: 1214 PKGAPTTPAA---TPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT 1270

Query: 266  P 266
            P
Sbjct: 1271 P 1271



 Score = 29.3 bits (64), Expect = 8.7
 Identities = 39/201 (19%), Positives = 67/201 (33%), Gaps = 30/201 (14%)

Query: 148  GPPPPVSKPSEPR---PSPEPQISIPV---KKEHIPGTLRFRLSPAARNILEKH------ 195
            G PPP   P+ P    PSP+   ++P      +  P T   +  P        H      
Sbjct: 1325 GTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAM 1384

Query: 196  ---------SLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESR-----PTPAPTATP 241
                     ++ + +G  T P  I           + + G  T S+     P   P +  
Sbjct: 1385 TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLK 1444

Query: 242  TAPSPLQATAGPSYPR----PVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKST 297
             AP+      GP+ P     P +P V+ P             +S+ ++  A        T
Sbjct: 1445 KAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPT 1504

Query: 298  VPHAYATADCDLGAVLKVRQD 318
            +P    ++  ++ A    R+D
Sbjct: 1505 LPAVIPSSPKEVPATPSSRRD 1525


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 38/131 (29%), Positives = 56/131 (42%), Gaps = 17/131 (12%)

Query: 155 KPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATGPRGIFTKE 214
           +P+ P PSP P  ++P K     GT     SP  R   ++ + ++   +A GP      +
Sbjct: 476 RPASPCPSPGPGHTLPPKPPSPRGTTA---SPKGRVRRKEEAKESP--SAAGPED--KSQ 528

Query: 215 DALKLVQLKQTGKITESRPTPAPTATPTAP--------SPLQATAGPSYPRPVIPPVSTP 266
              +    K++       P+PAP+ TP  P        +P  A    S P P  PPV TP
Sbjct: 529 SKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPA-PPV-TP 586

Query: 267 GQPNAVGTFTE 277
            +P A  T  E
Sbjct: 587 SKPMAGTTDRE 597



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 36/117 (30%), Positives = 46/117 (39%), Gaps = 20/117 (17%)

Query: 148 GPPPPV--SKPSEPRPSPE--PQISIPVKKEHIPGTLRFRLSPAARNILEKHSL---DAS 200
           G PP V    P EPRPSPE  P    P     +P T      PA +N      L     S
Sbjct: 12  GAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPP-DTPPAMKNATSSKQLPLEPES 70

Query: 201 QGTATGPRGIFTKEDALKLVQLKQTGKI------TESRP-----TPAPTATPTAPSP 246
                GPR    +E++    + K  G         ++RP      P+PTA P + SP
Sbjct: 71  PSGQVGPRPAPPQEES-PSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSP 126


>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
          Length = 1312

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 40/155 (25%), Positives = 59/155 (38%), Gaps = 31/155 (20%)

Query: 148 GPP------PPVSKPSEPRPSPEPQI---------SIPVKKEHIPGTLRFRLSPAARN-I 191
           GPP      PP+ +P EP+  P   +         + P   +  P       +P+AR  +
Sbjct: 557 GPPGPLSQTPPMQRPVEPQEGPHKSLQDQPTRNLAAFPASHDPDPAIPAPTATPSARGAV 616

Query: 192 LEKHSLDASQGTATGPRG---IFTKEDALKLVQLKQTGKITE--------SRPTPAPTAT 240
           + ++S   S+G    P     +    +A   V  + +   T         SRP  A  A 
Sbjct: 617 IRQNSDPTSEGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRAR 676

Query: 241 PTAPSP----LQATAGPSYPRPVIPPVSTPGQPNA 271
           P + S     LQ  A    P+P  PP   PG PNA
Sbjct: 677 PRSNSAWQIYLQRRAERGTPKPPGPPAQPPGPPNA 711



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 38/152 (25%), Positives = 54/152 (35%), Gaps = 31/152 (20%)

Query: 223 KQTGKITESRP------TPAPTATPTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFT 276
           +Q   + +S+P       P P A+P  P PL  T  P   RPV P      Q     +  
Sbjct: 532 QQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQT--PPMQRPVEP------QEGPHKSLQ 583

Query: 277 EIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKDDIKVSVNDFIIKAA 336
           + P  N+    A    +     P A  +A    GAV++   D   +    S N       
Sbjct: 584 DQPTRNLAAFPASHDPDPAIPAPTATPSA---RGAVIRQNSDPTSEGPGPSPN------- 633

Query: 337 AVTLKQMPDVNVSWDGEGPKQLPFIDISVAVA 368
                  P   V  D E P ++P    S+A A
Sbjct: 634 -------PPAWVRPDNEAPPKVPQRTSSIATA 658


>gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog A
           isoform 2 [Homo sapiens]
          Length = 548

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 43/174 (24%), Positives = 65/174 (37%), Gaps = 34/174 (19%)

Query: 145 KDVGPPPPVSKPSEPRPSPEPQISIPVKK-----EHIPGTLRFRLSPAARNILEKHSLDA 199
           K +    P S P++PRP P  +I++P +      +  P    F  S +  N  E  ++  
Sbjct: 307 KSIMKKSPFSGPTDPRPPPR-RIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVF 365

Query: 200 SQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPV 259
             G                  Q+ Q   +  + P   P A   AP+P   +A    P PV
Sbjct: 366 PSG------------------QISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPV 407

Query: 260 IPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVL 313
             PV  PG P AV      P       +++ L + +          D DLGA+L
Sbjct: 408 --PVLAPGPPQAVAPPAPKPTQAGEGTLSEALLQLQFD--------DEDLGALL 451


>gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog A
           isoform 1 [Homo sapiens]
          Length = 551

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 43/174 (24%), Positives = 65/174 (37%), Gaps = 34/174 (19%)

Query: 145 KDVGPPPPVSKPSEPRPSPEPQISIPVKK-----EHIPGTLRFRLSPAARNILEKHSLDA 199
           K +    P S P++PRP P  +I++P +      +  P    F  S +  N  E  ++  
Sbjct: 310 KSIMKKSPFSGPTDPRPPPR-RIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVF 368

Query: 200 SQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPV 259
             G                  Q+ Q   +  + P   P A   AP+P   +A    P PV
Sbjct: 369 PSG------------------QISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPV 410

Query: 260 IPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVL 313
             PV  PG P AV      P       +++ L + +          D DLGA+L
Sbjct: 411 --PVLAPGPPQAVAPPAPKPTQAGEGTLSEALLQLQFD--------DEDLGALL 454


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 38.1 bits (87), Expect = 0.019
 Identities = 37/160 (23%), Positives = 50/160 (31%), Gaps = 10/160 (6%)

Query: 144  PKDVGPPPPVSKPSEPRPSPEPQISI----PVKKEHIPGTLRFRLSPAARNILEKHSLDA 199
            P    P PP + PS P  +P P  +     P      P T      PA+   L   +  +
Sbjct: 1465 PPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPS 1524

Query: 200  SQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPV 259
               T T      T         +      T   PT  P+  PT  +    T  PS     
Sbjct: 1525 PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPS----- 1579

Query: 260  IPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVP 299
             PP +T   P  + T T  P +          T   +T P
Sbjct: 1580 -PPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTP 1618



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 34/129 (26%), Positives = 41/129 (31%), Gaps = 11/129 (8%)

Query: 143  IPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQG 202
            +P    P PP +  + P P+  P  S P      P T    L P         +      
Sbjct: 1517 LPPTTTPSPPTTTTTTPPPTTTP--SPPTTTPITPPTSTTTLPPTT-------TPSPPPT 1567

Query: 203  TATGPRGIFTKEDALKLVQLKQTGKITESRPT--PAPTATPTAPSPLQATAGPSYPRPVI 260
            T T P    T            T   T   PT  P+P  T T   P   T  P    P+ 
Sbjct: 1568 TTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1627

Query: 261  PPVSTPGQP 269
            PP ST   P
Sbjct: 1628 PPTSTTTLP 1636



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 31/132 (23%), Positives = 43/132 (32%), Gaps = 16/132 (12%)

Query: 143  IPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQG 202
            +P    P PP +  + P P+  P  S P+     P        P +       +   S  
Sbjct: 1416 LPPTTTPSPPTTTTTTPPPTTTP--SPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPP 1473

Query: 203  TATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPVIPP 262
            T T      T                T +  TP PT TP+ P+    T  P      +PP
Sbjct: 1474 TTTPSPPTTTPSPP------------TTTTTTPPPTTTPSPPTTTPIT--PPASTTTLPP 1519

Query: 263  VSTPGQPNAVGT 274
             +TP  P    T
Sbjct: 1520 TTTPSPPTTTTT 1531



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 38/151 (25%), Positives = 50/151 (33%), Gaps = 8/151 (5%)

Query: 150  PPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATGPRG 209
            PPP + PS P  +P   I+ P     +P T      P         +  +   T T    
Sbjct: 1612 PPPTTTPSPPTTTP---ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP 1668

Query: 210  IFTKEDALKLVQLKQTGKITESRPTPA---PTATPTAPSPLQATAGPSYPRPVIPPVSTP 266
            I T                T S PT     P+ T T  SP+  T  PS      PP +T 
Sbjct: 1669 ITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTM 1728

Query: 267  GQPNAVGTFTEIPASNIRRVIAKRLTESKST 297
              P+   T T  P +     +    T S  T
Sbjct: 1729 TTPSP--TTTPSPPTTTMTTLPPTTTSSPLT 1757



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 31/128 (24%), Positives = 40/128 (31%), Gaps = 5/128 (3%)

Query: 144  PKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGT 203
            P    P PP++  + P P+  P   I       P T     SP         +  +   T
Sbjct: 1433 PPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTP---SPPTTTPSPPTTTPSPPTT 1489

Query: 204  ATGPRGIFTKEDALKLVQLKQTGKITESRPT--PAPTATPTAPSPLQATAGPSYPRPVIP 261
             T      T         +      T   PT  P+P  T T   P   T  P    P+ P
Sbjct: 1490 TTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP 1549

Query: 262  PVSTPGQP 269
            P ST   P
Sbjct: 1550 PTSTTTLP 1557



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 2/73 (2%)

Query: 229  TESRPTPAPTATPTAPSPLQATAGPSYP--RPVIPPVSTPGQPNAVGTFTEIPASNIRRV 286
            T S PT  P+  PT+ + L  T  PS P      PP +T   P    T T  P +     
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPP 1457

Query: 287  IAKRLTESKSTVP 299
            I+   T   +T P
Sbjct: 1458 ISTTTTPPPTTTP 1470



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 30/123 (24%), Positives = 38/123 (30%), Gaps = 5/123 (4%)

Query: 149  PPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATGPR 208
            P PP + PS P   P    ++P      P T      P         +   +    T P 
Sbjct: 1399 PSPPTTTPSPP---PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS 1455

Query: 209  GIFTKEDALKLVQLKQTGKITESRPT--PAPTATPTAPSPLQATAGPSYPRPVIPPVSTP 266
               +                T S PT  P+P  T T   P   T  P    P+ PP ST 
Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTT 1515

Query: 267  GQP 269
              P
Sbjct: 1516 TLP 1518



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 38/161 (23%), Positives = 48/161 (29%), Gaps = 10/161 (6%)

Query: 144  PKDVGPPPPVSKPSEPRPS-PEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQG 202
            P     PPP + PS P  + P P    P      P        P         +   S  
Sbjct: 1566 PTTTTTPPPTTTPSPPTTTTPSP----PTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPP 1621

Query: 203  TATGPRGIFTKEDALKLVQLKQTGKITESRP----TPAPTATPTAPSPLQATAGPSYPRP 258
            T T P    T    L           T + P    TP+P  T T   P+  T  P     
Sbjct: 1622 TTT-PITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTT 1680

Query: 259  VIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVP 299
               P++T   P      T  P +     I    T S +T P
Sbjct: 1681 PSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTP 1721



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 13/36 (36%), Positives = 20/36 (55%)

Query: 231  SRPTPAPTATPTAPSPLQATAGPSYPRPVIPPVSTP 266
            S P+P PT + + P+P + ++ PS P P   P   P
Sbjct: 4378 STPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECP 4413



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 30/123 (24%), Positives = 41/123 (33%), Gaps = 14/123 (11%)

Query: 149  PPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSP------AARNILEKHSLDASQG 202
            PPP  S P   R +  P          +P  +    +       A       H+L     
Sbjct: 4214 PPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPS 4273

Query: 203  TATGP-----RGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYPR 257
            T T P     RG  T   +       QT   +   PTP P +T   PS ++ T    YP 
Sbjct: 4274 TTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLST---PSIIRTTGLRPYPS 4330

Query: 258  PVI 260
             V+
Sbjct: 4331 SVL 4333


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 37.7 bits (86), Expect = 0.025
 Identities = 38/165 (23%), Positives = 61/165 (36%), Gaps = 32/165 (19%)

Query: 142   EIPKDVGP------PPPVSKPSEPRPSPE-PQISIPVKKEHIPGTLRFRLSPAARNILEK 194
             E PK+V P      PPP      P   PE P++++P KK  +P  +  +       + E+
Sbjct: 10611 EAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKK--VPEAIPPKPESPPPEVFEE 10668

Query: 195   HSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPS 254
                         P  +  +E   ++V+        E    P  T  P  P P +      
Sbjct: 10669 ------------PEEVALEEPPAEVVEEP------EPAAPPQVTVPPKKPVPEKKAPAVV 10710

Query: 255   YPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVP 299
               +P +PPV  P  P  V     +P   +  V+ K+     + VP
Sbjct: 10711 AKKPELPPVKVPEVPKEV-----VPEKKVPLVVPKKPEAPPAKVP 10750



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 41/172 (23%), Positives = 58/172 (33%), Gaps = 16/172 (9%)

Query: 136  EDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKH 195
            E+   V IPK V PP P       +P PE +  +PV K+      +    P      EK 
Sbjct: 9298 EEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKI 9357

Query: 196  SLDASQGTATGP-------RGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQ 248
             +  ++     P       +G+ T+E    + Q        E  P PA    P    P +
Sbjct: 9358 PVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQ-------REESPPPAVPEIPKKKVPEE 9410

Query: 249  ATAGPSYPRPVIPPVSTPGQPN--AVGTFTEIPASNIRRVIAKRLTESKSTV 298
                P     V PP   P  P          +P    ++    R   SK TV
Sbjct: 9411 RKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTV 9462



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 35/169 (20%), Positives = 64/169 (37%), Gaps = 14/169 (8%)

Query: 131   IVEEGEDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARN 190
             + ++ E+   V IPK   PPP        +P PE ++ +PV K       +    PA   
Sbjct: 9981  VPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPK-------KVEAPPAKVP 10033

Query: 191   ILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQAT 250
              + K  +   +     P+ +  +    K+ ++ +     E +PTP P      P  +   
Sbjct: 10034 EVPKKPVPEKKVPVPAPKKV--EAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKV--- 10088

Query: 251   AGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVP 299
               P    PV  PV+ P +   +     +P   +     + L E +  +P
Sbjct: 10089 --PKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLP 10135



 Score = 36.2 bits (82), Expect = 0.071
 Identities = 39/163 (23%), Positives = 55/163 (33%), Gaps = 46/163 (28%)

Query: 136  EDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKH 195
            E+  HV I K V PPP V +  E +P+PE    +P+ K+  P                  
Sbjct: 9271 EEKIHVAISKRVEPPPKVPELPE-KPAPEEVAPVPIPKKVEP------------------ 9311

Query: 196  SLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSY 255
                                A K+ ++ +     E +P P P   P AP        P  
Sbjct: 9312 -------------------PAPKVPEVPKKPVPEEKKPVPVPKKEPAAP--------PKV 9344

Query: 256  PRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTV 298
            P     PV     P  V    E P + +  V    +TE K T+
Sbjct: 9345 PEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITI 9387



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 31/130 (23%), Positives = 52/130 (40%), Gaps = 19/130 (14%)

Query: 142   EIPKDVG-PPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDAS 200
             E P++V    PP     EP P+  PQ+++P KK  +P     + +PA   + +K  L   
Sbjct: 10667 EEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKP-VPE----KKAPAV--VAKKPELPP- 10718

Query: 201   QGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYP-RPV 259
                      +   E   ++V  K+   +   +P   P   P  P  +      + P +P 
Sbjct: 10719 ---------VKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPE 10769

Query: 260   IPPVSTPGQP 269
             +PP   P  P
Sbjct: 10770 VPPAKVPEVP 10779



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 44/177 (24%), Positives = 67/177 (37%), Gaps = 30/177 (16%)

Query: 131   IVEEGEDWKHVE----IPKDVGPPPPVSKPSEPR-PSPEPQISIPV--KKEHIPGTLRFR 183
             +VEE E++ H E      ++V P  PV  P  PR P PE +  +PV  KKE  P     +
Sbjct: 9922  LVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPA----K 9977

Query: 184   LSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTA 243
             +    +   EK  +   +     P          K+ ++ +     E  P P P      
Sbjct: 9978  VPEVPKKPEEKVPVLIPKKEKPPP---------AKVPEVPKKPVPEEKVPVPVPKKVEAP 10028

Query: 244   PSPLQATAGPSYPRPVIPPVSTP-GQPNAVGTFTEIPASNIRRVIAKRLTESKSTVP 299
             P+ +     P  P+  +P    P   P  V    E P + +  V  K + E K   P
Sbjct: 10029 PAKV-----PEVPKKPVPEKKVPVPAPKKV----EAPPAKVPEVPKKLIPEEKKPTP 10076



 Score = 32.7 bits (73), Expect = 0.79
 Identities = 34/139 (24%), Positives = 58/139 (41%), Gaps = 20/139 (14%)

Query: 133  EEGEDW-KHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNI 191
            EE E++    E P  V P P    P++P+  P   +   V +E +P  +  +L P    +
Sbjct: 9780 EEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKV 9839

Query: 192  LEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATA 251
             E+            P+ +F ++  + + + ++  ++TE    PA    P  P  + A  
Sbjct: 9840 PEE------------PKKVFEEKIRISITK-REKEQVTE----PA-AKVPMKPKRVVAEE 9881

Query: 252  GPSYPR-PVIPPVSTPGQP 269
                PR  V PPV  P  P
Sbjct: 9882 KVPVPRKEVAPPVRVPEVP 9900



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 35/150 (23%), Positives = 51/150 (34%), Gaps = 33/150 (22%)

Query: 142   EIPKDVGPPPPVSKPSEPRPSPE-------PQISIPVKKEHIPGTLRFRLSPAARNILEK 194
             E+PK +     V  P EPR  P        P+  +P KK  +P                 
Sbjct: 10471 EVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVP----------------- 10513

Query: 195   HSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPS---PLQATA 251
                 A +  A  P+     E   ++V  K+       +P   PT  P  P    P +   
Sbjct: 10514 ---PAKKPEAPPPK---VPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVP 10567

Query: 252   GPSYPRPVIPPVSTPGQPNAVGTFTEIPAS 281
                 P+P  PP   P  P  V    ++PA+
Sbjct: 10568 EAIPPKPESPPPEVPEAPKEVVPEKKVPAA 10597



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 36/177 (20%), Positives = 59/177 (33%), Gaps = 23/177 (12%)

Query: 132   VEEGEDWKHVEIPKDVGPPPPVSK----PSEPRPSPEPQISIPVKKEHIPGTLRFRLSPA 187
             V E E+ +  E PK     P +S+    P +P     P+   P K   +P          
Sbjct: 10424 VFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVP---------- 10473

Query: 188   ARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPS-- 245
              + I+ +  +   +     P  +       ++V  K+       +P   P   P AP   
Sbjct: 10474 -KKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEV 10532

Query: 246   -PLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVPHA 301
              P +    P   +P +PP   P  P A      +P   +   I  +       VP A
Sbjct: 10533 VPEKKVPVPPPKKPEVPPTKVPEVPKAA-----VPEKKVPEAIPPKPESPPPEVPEA 10584



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 9/89 (10%)

Query: 114  VVEEGSKNIRLGSLIGLIVEEGEDWKHVEIPKDVGP----PPPVSKPSE---PRPSPEPQ 166
            V E   K I L   I   +EE    K  E PK + P    P PV K  +   P+   EP+
Sbjct: 9554 VTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPK 9613

Query: 167  ISIPVKKEHIPGTLRFRLSPAARNILEKH 195
              +P KK  +P  +     P    + E+H
Sbjct: 9614 KPVPEKK--VPPKVIKMEEPLPAKVTERH 9640



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 33/160 (20%), Positives = 57/160 (35%), Gaps = 25/160 (15%)

Query: 110   LAKIVVEEGSKNIRLGSLIGLIVE---EGEDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQ 166
             L  + V E  K +     + L+V    E    K  E+PK+V P   V+ P +P   P   
Sbjct: 10716 LPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKV 10775

Query: 167   ISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTG 226
               +P K                  + EK ++   +   + P  ++ + +     ++    
Sbjct: 10776 PEVPKKPV----------------LEEKPAVPVPERAESPPPEVYEEPE-----EIAPEE 10814

Query: 227   KITESRPTPAPTATPTAPSPLQATAGPSYPRPVIPPVSTP 266
             +I      P P A    P  +   A P  P+ +IP    P
Sbjct: 10815 EIAPEEEKPVPVAEEEEPE-VPPPAVPEEPKKIIPEKKVP 10853


>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
           [Homo sapiens]
          Length = 1132

 Score = 37.7 bits (86), Expect = 0.025
 Identities = 35/118 (29%), Positives = 46/118 (38%), Gaps = 24/118 (20%)

Query: 148 GPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQG----- 202
           GPPPP++ P    P   P ISIP              +     I E  + D S G     
Sbjct: 727 GPPPPITPPVSIPPPHTPPISIP--------------NSTIAGINEDTTKDLSIGNPIPT 772

Query: 203 TATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPVI 260
             +G RG     D++K+        +  + PT  PT   T P  L  T G + P PVI
Sbjct: 773 VVSGARGNAESGDSVKM----YGSAVPPAAPTNLPTPPVTQPVSLLGTQGVA-PGPVI 825


>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
           [Homo sapiens]
          Length = 1147

 Score = 37.7 bits (86), Expect = 0.025
 Identities = 35/118 (29%), Positives = 46/118 (38%), Gaps = 24/118 (20%)

Query: 148 GPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQG----- 202
           GPPPP++ P    P   P ISIP              +     I E  + D S G     
Sbjct: 742 GPPPPITPPVSIPPPHTPPISIP--------------NSTIAGINEDTTKDLSIGNPIPT 787

Query: 203 TATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPVI 260
             +G RG     D++K+        +  + PT  PT   T P  L  T G + P PVI
Sbjct: 788 VVSGARGNAESGDSVKM----YGSAVPPAAPTNLPTPPVTQPVSLLGTQGVA-PGPVI 840


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 37.7 bits (86), Expect = 0.025
 Identities = 32/127 (25%), Positives = 45/127 (35%), Gaps = 8/127 (6%)

Query: 143 IPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQG 202
           +P    PPPP   P  P P P P  S P      P  +++      +N   +HS  A   
Sbjct: 628 LPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQN-ASQHS-GALFK 685

Query: 203 TATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPVIPP 262
             T P  +   +     + +   G +    P P P   P  P    A   P+   P +P 
Sbjct: 686 PPTPP--VMQSQSVKPQILVPPNGVV----PPPPPPPPPPTPGSAMAQLKPAPCAPSLPQ 739

Query: 263 VSTPGQP 269
            S P  P
Sbjct: 740 FSAPPPP 746



 Score = 36.2 bits (82), Expect = 0.071
 Identities = 34/126 (26%), Positives = 45/126 (35%), Gaps = 22/126 (17%)

Query: 144 PKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGT 203
           P    PPPP+  P  P+  P+P ++IP              +P +   +      A+  T
Sbjct: 760 PPTPPPPPPIPAPLPPQAPPKPLVTIP--------------APTSTKTVAPVVTQAAPPT 805

Query: 204 ATGPRGIFTKEDALKLVQLKQTGKITESRPT-PAPTATPTAPSPLQATAGPSYPRPVIPP 262
            T P     K+ A           I  S PT P P   PT P      A P  P P+ P 
Sbjct: 806 PTPPVPPAKKQPAF------PASYIPPSPPTPPVPVPPPTLPKQQSFCAKPP-PSPLSPV 858

Query: 263 VSTPGQ 268
            S   Q
Sbjct: 859 PSVVKQ 864



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 34/120 (28%), Positives = 46/120 (38%), Gaps = 13/120 (10%)

Query: 144 PKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILE-KHSLDASQG 202
           P  V PPPP   P  P P+P   ++        P   +F   P    I + +H    +  
Sbjct: 705 PNGVVPPPP---PPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPP 761

Query: 203 TATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPVIPP 262
           T   P  I     A    Q      +T     PAPT+T T  +P+   A P  P P +PP
Sbjct: 762 TPPPPPPI----PAPLPPQAPPKPLVT----IPAPTSTKTV-APVVTQAAPPTPTPPVPP 812



 Score = 29.3 bits (64), Expect = 8.7
 Identities = 25/99 (25%), Positives = 36/99 (36%), Gaps = 1/99 (1%)

Query: 147  VGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRL-SPAARNILEKHSLDASQGTAT 205
            V PPPP S    P P P P  S    K   PG    +  SP  +        ++S  +++
Sbjct: 926  VFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSS 985

Query: 206  GPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAP 244
            G      K  ++  +  K T       P+      P AP
Sbjct: 986  GAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAP 1024


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 37.7 bits (86), Expect = 0.025
 Identities = 42/154 (27%), Positives = 60/154 (38%), Gaps = 28/154 (18%)

Query: 149 PPPPVSKPS------EPRPSPEPQISIPVKKEHIPGTLR-----------FRLSPAARNI 191
           P PP S P        P PSPEPQ   PV  E +  TL              L P + + 
Sbjct: 185 PEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASS 244

Query: 192 LEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRP-TPAPTATPTAPSPLQAT 250
            E   L AS     GP    + E        +++ + T   P  P+P+ +P    P  A 
Sbjct: 245 PESPVLAASP-EPWGPSPAASPES-------RKSARTTSPEPRKPSPSESPEPWKPFPAV 296

Query: 251 A-GPSYPRPVIPPVS-TPGQPNAVGTFTEIPASN 282
           +  P  P P + P S  PG P +   +   P+++
Sbjct: 297 SPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSAS 330


>gi|40807465 zinc finger protein 341 [Homo sapiens]
          Length = 847

 Score = 37.7 bits (86), Expect = 0.025
 Identities = 40/145 (27%), Positives = 51/145 (35%), Gaps = 17/145 (11%)

Query: 144 PKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGT 203
           P    PPPP+  P  P+P P P  S+       PG    R +P    ++E +S       
Sbjct: 179 PPPPPPPPPLPPPPPPQPPPPPPQSLGP-----PG----RPNPGGNGVVEVYS------A 223

Query: 204 ATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPVIPPV 263
           A    G  T E     +Q     ++      P    TPT  SP +    P  P P  P  
Sbjct: 224 AAPLAGSGTVEIQALGMQPYPPLEVPNQCVEPPVYPTPTVYSPGKQGFKPKGPNPAAPMT 283

Query: 264 STPGQPNAVGTFTEIPASNIRRVIA 288
           S  G    V TF        RR  A
Sbjct: 284 SATG--GTVATFDSPATLKTRRAKA 306


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 37.4 bits (85), Expect = 0.032
 Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 16/132 (12%)

Query: 218  KLVQLKQTGKITESRPTPAPT-ATPTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFT 276
            ++  +++TG + + +  P+PT ATPT P+  Q T  P  P+P   P  TP  PN++  + 
Sbjct: 1831 RMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTT-PQTPQPTSQPQPTP--PNSMPPY- 1886

Query: 277  EIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKDDIKVSVNDFIIKAA 336
             +P +     +++     + T P    TA   L        ++             I+ A
Sbjct: 1887 -LPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQ----------IQRA 1935

Query: 337  AVTLKQMPDVNV 348
            A T +QM  V +
Sbjct: 1936 AETQRQMAHVQI 1947


>gi|7706469 Kruppel-like factor [Homo sapiens]
          Length = 355

 Score = 37.4 bits (85), Expect = 0.032
 Identities = 44/172 (25%), Positives = 58/172 (33%), Gaps = 23/172 (13%)

Query: 116 EEGSKNIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIP----- 170
           E G  +  L S++  I+  G D    E   +  PPPP      P P   P  S P     
Sbjct: 33  ESGGTDDDLNSVLDFILSMGLDGLGAEAAPEPPPPPPPPAFYYPEPGAPPPYSAPAGGLV 92

Query: 171 --VKKEHIPGTL------RFRLSPAARNI-LEKHSLD------ASQGTATGPRGIFTKED 215
             + +  +   L      RF L+P  R +  E    D       + G   GPRG+  +E 
Sbjct: 93  SELLRPELDAPLGPALHGRFLLAPPGRLVKAEPPEADGGGGYGCAPGLTRGPRGL-KREG 151

Query: 216 ALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPVIPPVSTPG 267
           A         G     RP P P   P +P        P       PP   PG
Sbjct: 152 APGPAASCMRG--PGGRPPPPPDTPPLSPDGPARLPAPGPRASFPPPFGGPG 201


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score = 37.4 bits (85), Expect = 0.032
 Identities = 49/196 (25%), Positives = 72/196 (36%), Gaps = 50/196 (25%)

Query: 111 AKIVVEEGSKNI----------RLGS--LIGLIVEEGEDWKHVE------IPKDVGPPP- 151
           A +V E+  KN+          RL S  L  + +E+ E WK          PK V P P 
Sbjct: 111 ACVVCEDCKKNVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPM 170

Query: 152 ---------PVSKPSEP-RPSPEPQ--ISIPVKKEH----------------IPGTLRFR 183
                    PVS+P+ P +P+PEP+     P + +                  PG  R  
Sbjct: 171 PIKKTKPQQPVSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPG--RGN 228

Query: 184 LSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTA 243
             P  R   E     +S+ + +        + +     L++   +  SRP P    +P  
Sbjct: 229 YGPPVRRASEARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAP 288

Query: 244 PSPLQ-ATAGPSYPRP 258
           P P Q  T G S P P
Sbjct: 289 PQPGQPGTPGGSRPGP 304


>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
          Length = 690

 Score = 37.4 bits (85), Expect = 0.032
 Identities = 49/196 (25%), Positives = 72/196 (36%), Gaps = 50/196 (25%)

Query: 111 AKIVVEEGSKNI----------RLGS--LIGLIVEEGEDWKHVE------IPKDVGPPP- 151
           A +V E+  KN+          RL S  L  + +E+ E WK          PK V P P 
Sbjct: 107 ACVVCEDCKKNVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPM 166

Query: 152 ---------PVSKPSEP-RPSPEPQ--ISIPVKKEH----------------IPGTLRFR 183
                    PVS+P+ P +P+PEP+     P + +                  PG  R  
Sbjct: 167 PIKKTKPQQPVSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPG--RGN 224

Query: 184 LSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTA 243
             P  R   E     +S+ + +        + +     L++   +  SRP P    +P  
Sbjct: 225 YGPPVRRASEARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAP 284

Query: 244 PSPLQ-ATAGPSYPRP 258
           P P Q  T G S P P
Sbjct: 285 PQPGQPGTPGGSRPGP 300


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 37.4 bits (85), Expect = 0.032
 Identities = 37/139 (26%), Positives = 54/139 (38%), Gaps = 24/139 (17%)

Query: 141  VEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDAS 200
            ++I     PPPP   P  P P P P   +P      P T     SP    + +K    AS
Sbjct: 2399 LDISAQPPPPPPPPPPPPPPPPPPPPPPLP------PPT-----SPKPTILPKKKLTVAS 2447

Query: 201  QGTATGPRGIFTKEDALKLVQLKQTG-----KITESRPTPAPTATPTAPSPL------QA 249
              T   P  +F     L+   + ++      +I  + P P P    + PS L      + 
Sbjct: 2448 PVTTATP--LFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEP 2505

Query: 250  TAGPSYPRPVIPPVSTPGQ 268
            +  P  P+PVIP + T  Q
Sbjct: 2506 SKPPIAPKPVIPQLPTTTQ 2524



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 46/184 (25%), Positives = 71/184 (38%), Gaps = 23/184 (12%)

Query: 96  DKAVVTLDASDDGILAKIVVEEGSKNIRLGSLIGLIVEEGEDWKHVEI---PKDVGPPPP 152
           D   +   ASD    +KI+   G  +   G      V++ E+ K  +    PK    P P
Sbjct: 817 DSKAIPRPASD----SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP 872

Query: 153 VSKPSEPRPSPEPQISIPVKKEH---IPGTLRFRLSPAARNILEKHSLDASQGTATGP-- 207
              P+ P P P    ++P  ++       + RF L+  +     K      Q T TG   
Sbjct: 873 KGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLF 932

Query: 208 ---RGIFTKEDALKLVQLKQTGKITESRP------TPAPTATPTAPSPLQATA-GPSYPR 257
                IF++   L +    Q G  ++S P       PAP+  PT+  P ++T   P  P 
Sbjct: 933 GFGASIFSQASNL-ISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPA 991

Query: 258 PVIP 261
             IP
Sbjct: 992 KSIP 995



 Score = 32.7 bits (73), Expect = 0.79
 Identities = 40/145 (27%), Positives = 58/145 (40%), Gaps = 17/145 (11%)

Query: 148 GPPP---PVSKPSEPRPSPEPQ----ISIPVKKEHIPGTLRFRLSPAARNILEKHSLDAS 200
           G PP   P  + S+P P+  P     ++ P+ ++  PGT++  + P          L  +
Sbjct: 312 GKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQ--PGTVKPPVQPPGTTKPPAQPLGPA 369

Query: 201 QGTA--TGPRGIFTKEDALK-LVQLKQTGKITESRPTPA--PTATPTAPSPLQATAGPSY 255
           +  A  TG     +++   K L Q    GK    +P PA  PT     P PL    G   
Sbjct: 370 KPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQS 429

Query: 256 PRPVIPPVSTPGQPNAVGTFTEIPA 280
           P     P  TP Q    G   +IPA
Sbjct: 430 PAKAPGPTKTPVQQPGPG---KIPA 451



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 28/120 (23%), Positives = 50/120 (41%), Gaps = 8/120 (6%)

Query: 149 PPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATGPR 208
           P   V   +E + +P  +       +  P T   ++SP     + + + D+   +  GP 
Sbjct: 779 PSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGE-KVSPFDSKAIPRPASDSKIISHPGPS 837

Query: 209 GIFTKEDALKLVQLKQTGKITESRPTPAPTA------TPTAPSPLQATAGPSYPRPVIPP 262
                +  +  VQ K+  K  +++ +P P A      +PT P P + TAG + P P   P
Sbjct: 838 SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGP-RPTAGQTVPTPQQSP 896



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 34/129 (26%), Positives = 42/129 (32%), Gaps = 26/129 (20%)

Query: 144 PKDVGPPPPVSKPSEPRPSPEP----QISIPVKKEHIPGTLRFRLSPAARNILEKHSLDA 199
           PK +  PP V K    +P P      Q+  P      PG      SPA            
Sbjct: 388 PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ----SPAK----------- 432

Query: 200 SQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTA-PSPLQATAGPSYPRP 258
               A GP     ++     +  +Q G    S     PT  P+  P P  A   P  P P
Sbjct: 433 ----APGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP--AKPPPQQPGP 486

Query: 259 VIPPVSTPG 267
             PP   PG
Sbjct: 487 AKPPPQQPG 495


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 37.4 bits (85), Expect = 0.032
 Identities = 37/139 (26%), Positives = 54/139 (38%), Gaps = 24/139 (17%)

Query: 141  VEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDAS 200
            ++I     PPPP   P  P P P P   +P      P T     SP    + +K    AS
Sbjct: 2399 LDISAQPPPPPPPPPPPPPPPPPPPPPPLP------PPT-----SPKPTILPKKKLTVAS 2447

Query: 201  QGTATGPRGIFTKEDALKLVQLKQTG-----KITESRPTPAPTATPTAPSPL------QA 249
              T   P  +F     L+   + ++      +I  + P P P    + PS L      + 
Sbjct: 2448 PVTTATP--LFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEP 2505

Query: 250  TAGPSYPRPVIPPVSTPGQ 268
            +  P  P+PVIP + T  Q
Sbjct: 2506 SKPPIAPKPVIPQLPTTTQ 2524



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 46/184 (25%), Positives = 71/184 (38%), Gaps = 23/184 (12%)

Query: 96  DKAVVTLDASDDGILAKIVVEEGSKNIRLGSLIGLIVEEGEDWKHVEI---PKDVGPPPP 152
           D   +   ASD    +KI+   G  +   G      V++ E+ K  +    PK    P P
Sbjct: 817 DSKAIPRPASD----SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP 872

Query: 153 VSKPSEPRPSPEPQISIPVKKEH---IPGTLRFRLSPAARNILEKHSLDASQGTATGP-- 207
              P+ P P P    ++P  ++       + RF L+  +     K      Q T TG   
Sbjct: 873 KGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLF 932

Query: 208 ---RGIFTKEDALKLVQLKQTGKITESRP------TPAPTATPTAPSPLQATA-GPSYPR 257
                IF++   L +    Q G  ++S P       PAP+  PT+  P ++T   P  P 
Sbjct: 933 GFGASIFSQASNL-ISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPA 991

Query: 258 PVIP 261
             IP
Sbjct: 992 KSIP 995



 Score = 32.7 bits (73), Expect = 0.79
 Identities = 40/145 (27%), Positives = 58/145 (40%), Gaps = 17/145 (11%)

Query: 148 GPPP---PVSKPSEPRPSPEPQ----ISIPVKKEHIPGTLRFRLSPAARNILEKHSLDAS 200
           G PP   P  + S+P P+  P     ++ P+ ++  PGT++  + P          L  +
Sbjct: 312 GKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQ--PGTVKPPVQPPGTTKPPAQPLGPA 369

Query: 201 QGTA--TGPRGIFTKEDALK-LVQLKQTGKITESRPTPA--PTATPTAPSPLQATAGPSY 255
           +  A  TG     +++   K L Q    GK    +P PA  PT     P PL    G   
Sbjct: 370 KPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQS 429

Query: 256 PRPVIPPVSTPGQPNAVGTFTEIPA 280
           P     P  TP Q    G   +IPA
Sbjct: 430 PAKAPGPTKTPVQQPGPG---KIPA 451



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 28/120 (23%), Positives = 50/120 (41%), Gaps = 8/120 (6%)

Query: 149 PPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATGPR 208
           P   V   +E + +P  +       +  P T   ++SP     + + + D+   +  GP 
Sbjct: 779 PSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGE-KVSPFDSKAIPRPASDSKIISHPGPS 837

Query: 209 GIFTKEDALKLVQLKQTGKITESRPTPAPTA------TPTAPSPLQATAGPSYPRPVIPP 262
                +  +  VQ K+  K  +++ +P P A      +PT P P + TAG + P P   P
Sbjct: 838 SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGP-RPTAGQTVPTPQQSP 896



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 34/129 (26%), Positives = 42/129 (32%), Gaps = 26/129 (20%)

Query: 144 PKDVGPPPPVSKPSEPRPSPEP----QISIPVKKEHIPGTLRFRLSPAARNILEKHSLDA 199
           PK +  PP V K    +P P      Q+  P      PG      SPA            
Sbjct: 388 PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ----SPAK----------- 432

Query: 200 SQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTA-PSPLQATAGPSYPRP 258
               A GP     ++     +  +Q G    S     PT  P+  P P  A   P  P P
Sbjct: 433 ----APGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP--AKPPPQQPGP 486

Query: 259 VIPPVSTPG 267
             PP   PG
Sbjct: 487 AKPPPQQPG 495


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 37.4 bits (85), Expect = 0.032
 Identities = 40/159 (25%), Positives = 61/159 (38%), Gaps = 40/159 (25%)

Query: 144  PKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGT 203
            P  V PPP     ++P P P PQ+        +P +L    SPA   ++           
Sbjct: 1021 PVPVRPPPGPELSAQPTPGPVPQV--------LPASLMVSASPAGPPLI----------P 1062

Query: 204  ATGPRG------IFTKEDALKLVQLKQTGKI--TESRPTPAPTATPTAPSPLQATAGP-- 253
            A+ P G      +     +L  V     G +  T   PTP  +  PT P+P++ +  P  
Sbjct: 1063 ASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPP 1122

Query: 254  ---SYPRPV-IPP--------VSTPGQPNAVGTFTEIPA 280
               S  +P+ +PP         +T     A  T T +PA
Sbjct: 1123 GSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPA 1161



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 49/188 (26%), Positives = 70/188 (37%), Gaps = 45/188 (23%)

Query: 149  PPPPVSKPSEPRPS-------------------PEPQISIPVKKEHIPGTLRFRLSPAAR 189
            P PP   PS   PS                   P   + +     H+PG L   ++PA  
Sbjct: 1488 PGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPG-LNSTVAPACS 1546

Query: 190  NILEKHSLDAS-----------QGTATGPRGIFTKEDALKLVQLK--QTGKITESRPTPA 236
             +L   S  AS           Q +   P    ++  A  L  +   QT  +    P+PA
Sbjct: 1547 PVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILA---PSPA 1603

Query: 237  PTATPT---APSPLQAT--AGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRL 291
            P   P    APSP  A   A    P PV+ P STPG   ++ + + +PA     V+A   
Sbjct: 1604 PPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPG--TSLASASPVPAPT--PVLAPSS 1659

Query: 292  TESKSTVP 299
            T++    P
Sbjct: 1660 TQTMLPAP 1667


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,283,938
Number of Sequences: 37866
Number of extensions: 1168514
Number of successful extensions: 11358
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 371
Number of HSP's that attempted gapping in prelim test: 8182
Number of HSP's gapped (non-prelim): 2847
length of query: 501
length of database: 18,247,518
effective HSP length: 106
effective length of query: 395
effective length of database: 14,233,722
effective search space: 5622320190
effective search space used: 5622320190
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.