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Search of human proteins with 20127486
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20127486 mannose 6 phosphate receptor binding protein 1
[Homo sapiens]
(434 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20127486 mannose 6 phosphate receptor binding protein 1 [Homo... 833 0.0
gi|34577059 adipose differentiation-related protein [Homo sapiens] 351 6e-97
gi|116292172 lipid storage droplet protein 5 [Homo sapiens] 285 7e-77
gi|223718196 perilipin [Homo sapiens] 120 3e-27
gi|223718203 perilipin [Homo sapiens] 120 3e-27
gi|122937195 plasma membrane associated protein, S3-12 [Homo sap... 108 1e-23
gi|21264602 laminin alpha 5 [Homo sapiens] 48 2e-05
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 47 3e-05
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 47 3e-05
gi|16262452 cingulin [Homo sapiens] 46 6e-05
gi|40538794 coiled-coil domain containing 21 [Homo sapiens] 45 1e-04
gi|221139761 zinc finger protein 853 [Homo sapiens] 44 4e-04
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 44 4e-04
gi|33188443 microfilament and actin filament cross-linker protei... 43 5e-04
gi|33188445 microfilament and actin filament cross-linker protei... 43 5e-04
gi|71773110 apolipoprotein A-IV precursor [Homo sapiens] 42 0.001
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 42 0.001
gi|21735548 centrosomal protein 2 [Homo sapiens] 41 0.002
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 40 0.003
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 40 0.003
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 40 0.005
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom... 38 0.021
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom... 38 0.021
gi|156938343 talin 2 [Homo sapiens] 37 0.027
gi|223029410 talin 1 [Homo sapiens] 37 0.035
gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 37 0.046
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 37 0.046
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 36 0.078
gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens] 36 0.078
gi|56550043 sarcolemma associated protein [Homo sapiens] 36 0.078
>gi|20127486 mannose 6 phosphate receptor binding protein 1 [Homo
sapiens]
Length = 434
Score = 833 bits (2151), Expect = 0.0
Identities = 434/434 (100%), Positives = 434/434 (100%)
Query: 1 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC 60
MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC
Sbjct: 1 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC 60
Query: 61 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD 120
DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD
Sbjct: 61 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD 120
Query: 121 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR 180
TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR
Sbjct: 121 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR 180
Query: 181 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG 240
LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG
Sbjct: 181 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG 240
Query: 241 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQM 300
SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQM
Sbjct: 241 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQM 300
Query: 301 WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ 360
WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ
Sbjct: 301 WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ 360
Query: 361 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP 420
QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP
Sbjct: 361 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP 420
Query: 421 FAPGITEKAPEEKK 434
FAPGITEKAPEEKK
Sbjct: 421 FAPGITEKAPEEKK 434
>gi|34577059 adipose differentiation-related protein [Homo sapiens]
Length = 437
Score = 351 bits (901), Expect = 6e-97
Identities = 175/409 (42%), Positives = 275/409 (67%), Gaps = 9/409 (2%)
Query: 22 QPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVCDAAEKGVRTLTAAAVSGAQPI 81
QPSVV RV ++PL+SST D++S+AY STK+ YP++K+VC+ AE GV+T+T+ A++ A PI
Sbjct: 9 QPSVVTRVVNLPLVSSTYDLMSSAYLSTKDQYPYLKSVCEMAENGVKTITSVAMTSALPI 68
Query: 82 LSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAKD 141
+ KLEPQIA A+ YA +GLD++EE LPIL QP+ +++A+ K V+ V+ AKD
Sbjct: 69 IQKLEPQIAVANTYACKGLDRIEERLPILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKD 128
Query: 142 TVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEEWAD 201
+VA+ ++ +D T+GAV V+KTKSVV+G + +V+GSR+ Q+V SGV+ L KSE +
Sbjct: 129 SVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVE 188
Query: 202 NHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYEHSLGKLRAT 261
+LPLT+ EL + A ++GFD+ Q+ SY+VRLGSLS +L AY+ +L +++
Sbjct: 189 QYLPLTEEELEKEAKKVEGFDLV------QKPSYYVRLGSLSTKLHSRAYQQALSRVKEA 242
Query: 262 KQRAQEALLQLSQALSLMETVKQGV---DQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPK 318
KQ++Q+ + QL + L+E ++ V +QK+ + Q+KL+ W+ W + E
Sbjct: 243 KQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWVEWKRSIGYDDTDESHC 302
Query: 319 PEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQARRQVEDLQATFSSIHS 378
E +ESR L + R++ QQLQ TC +L S+IQG+P N++DQ + D+ + F + S
Sbjct: 303 AEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMGVMAGDIYSVFRNAAS 362
Query: 379 FQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGPFAPGITE 427
F+++S S+L S+ ++ +E+LD +++Y+ NTP+ WLVGPF P +TE
Sbjct: 363 FKEVSDSLLTSSKGQLQKMKESLDDVMDYLVNNTPLNWLVGPFYPQLTE 411
>gi|116292172 lipid storage droplet protein 5 [Homo sapiens]
Length = 463
Score = 285 bits (728), Expect = 7e-77
Identities = 162/407 (39%), Positives = 233/407 (57%), Gaps = 40/407 (9%)
Query: 22 QPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVCDAAEKGVRTLTAAAVSGAQPI 81
Q +VV RV ++PL+ +TC V Y++ K+ +P + + C AE V LT A+ AQP+
Sbjct: 19 QQNVVQRVVALPLVRATCTAVCDVYSAAKDRHPLLGSACRLAENCVCGLTTRALDHAQPL 78
Query: 82 LSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAKD 141
L L+PQ+A+ + A RGLDKLEE LP LQQP+E V V+SAKD
Sbjct: 79 LEHLQPQLATMNSLACRGLDKLEEKLPFLQQPSETV------------------VTSAKD 120
Query: 142 TVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEEWAD 201
VA+ ++ VD R + V+ +SV VD VL KSEE D
Sbjct: 121 VVASSVTGVVDLARRGRRWSVELKRSVS-----------------HAVDVVLEKSEELVD 163
Query: 202 NHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYEHSLGKLRAT 261
+ LP+T+ ELA +A +G +V SV+ QR++Q YFVRLGSLS R+R AYEHS+GKLR +
Sbjct: 164 HFLPMTEEELAALAAEAEGPEVGSVEDQRRQQGYFVRLGSLSARIRHLAYEHSVGKLRQS 223
Query: 262 KQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQ 321
K RAQ+ L QL + L L++ ++ GV K+H++W W Q+ E + Q
Sbjct: 224 KHRAQDTLAQLQETLELIDHMQCGVTPTAPACPGKVHELWGEWGQR-----PPESRRRSQ 278
Query: 322 VESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQARRQVEDLQATFSSIHSFQD 381
E L + R + Q+LQ T +L SS++GLP +++V + RR V+ LQ F+ F+D
Sbjct: 279 AELETLVLSRSLTQELQGTVEALESSVRGLPAGAQEKVAEVRRSVDALQTAFADARCFRD 338
Query: 382 LSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGPFAPGITEK 428
+ ++ LA+ R RVA A +D ++E V Q P+ WLVGPFAP + E+
Sbjct: 339 VPAAALAEGRGRVAHAHACVDELLELVVQAVPLPWLVGPFAPILVER 385
>gi|223718196 perilipin [Homo sapiens]
Length = 522
Score = 120 bits (300), Expect = 3e-27
Identities = 68/232 (29%), Positives = 123/232 (53%), Gaps = 12/232 (5%)
Query: 21 QQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVCDAAEKGVRTLTAAAVSGAQP 80
+Q +V+ RV +P++S TC+ Y STKE++P + +VC+A EKGV++ ++ A +P
Sbjct: 16 EQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEP 75
Query: 81 ILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAK 140
++ +L Q +A+E A RGLD LEE +P LQ P EK+ ++ K+ +S++ + SA+
Sbjct: 76 VVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKDTISTR-------LRSAR 128
Query: 141 DTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEEWA 200
++++ ++ D GA +G + V + +R G++ G D LG E+
Sbjct: 129 NSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLALGSIEKVV 188
Query: 201 DNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYE 252
+ LP E A G A + + + S R+G+L+ L ++ +
Sbjct: 189 EYLLPPDKEESA----PAPGHQQAQ-KSPKAKPSLLSRVGALTNTLSRYTVQ 235
>gi|223718203 perilipin [Homo sapiens]
Length = 522
Score = 120 bits (300), Expect = 3e-27
Identities = 68/232 (29%), Positives = 123/232 (53%), Gaps = 12/232 (5%)
Query: 21 QQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVCDAAEKGVRTLTAAAVSGAQP 80
+Q +V+ RV +P++S TC+ Y STKE++P + +VC+A EKGV++ ++ A +P
Sbjct: 16 EQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEP 75
Query: 81 ILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAK 140
++ +L Q +A+E A RGLD LEE +P LQ P EK+ ++ K+ +S++ + SA+
Sbjct: 76 VVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKDTISTR-------LRSAR 128
Query: 141 DTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEEWA 200
++++ ++ D GA +G + V + +R G++ G D LG E+
Sbjct: 129 NSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLALGSIEKVV 188
Query: 201 DNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYE 252
+ LP E A G A + + + S R+G+L+ L ++ +
Sbjct: 189 EYLLPPDKEESA----PAPGHQQAQ-KSPKAKPSLLSRVGALTNTLSRYTVQ 235
>gi|122937195 plasma membrane associated protein, S3-12 [Homo sapiens]
Length = 1357
Score = 108 bits (269), Expect = 1e-23
Identities = 113/480 (23%), Positives = 188/480 (39%), Gaps = 98/480 (20%)
Query: 15 TVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVCDAAEKGVRTLTAAA 74
TV+ V V + S V+ A + + KTV A+ V T A
Sbjct: 898 TVQTGVDTSKTVLTGTKDTVCSGVTGAVNVAKGTVQTGVDTAKTVLSGAKDAVTTGVTGA 957
Query: 75 VSGAQ-------------------PILSKLEPQIASASEYAHRGLDKLEENLPILQQPTE 115
V+ A+ + S + ++ A GLD T+
Sbjct: 958 VNVAKGTVQTGVDASKAVLMGTKDTVFSGVTGAMSMAKGAVQGGLDT-----------TK 1006
Query: 116 KVLADTKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQS 175
VL TK+ VS+ + G+ + + A T + + +T G+ +++ GG Q+
Sbjct: 1007 TVLTGTKDAVSAGLMGSGNVATGATHTGLSTFQNWLPSTPATSWGGLTSSRTTDNGGEQT 1066
Query: 176 VMGSRLGQMVLSGVDTV-----LGKSEEW------------------------------A 200
+ + + SG+ T +G W A
Sbjct: 1067 ALSPQ--EAPFSGISTPPDVLSVGPEPAWEAAATTKGLATDVATFTQGAAPGREDTGLLA 1124
Query: 201 DNHLPLTDAELARIATSLDG----FDVASVQQQRQ--------------EQSYFVRLGSL 242
H P LA + L+G F + ++Q Q + SYFVRLG L
Sbjct: 1125 TTHGPEEAPRLAMLQNELEGLGDIFHPMNAEEQAQLAASQPGPKVLSAEQGSYFVRLGDL 1184
Query: 243 SERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQMWL 302
RQ A+EH++ L+ + +A++ L QL L+E +Q EGQ +L Q
Sbjct: 1185 GPSFRQRAFEHAVSHLQHGQFQARDTLAQLQDCFRLIEKAQQAP-----EGQPRLDQ--- 1236
Query: 303 SWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQA 362
++ E+ ++ L+ + +QL + L SS+QGLP ++ V +A
Sbjct: 1237 -----GSGASAEDAAVQEERDAGVLSRVCGLLRQLHTAYSGLVSSLQGLPAELQQPVGRA 1291
Query: 363 RRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGPFA 422
R + +L +S S ++L + L QSRE V A + L+ ++E + N P++WLVGPFA
Sbjct: 1292 RHSLCELYGIVASAGSVEELPAERLVQSREGVHQAWQGLEQLLEGLQHNPPLSWLVGPFA 1351
Score = 57.4 bits (137), Expect = 3e-08
Identities = 49/159 (30%), Positives = 75/159 (47%), Gaps = 22/159 (13%)
Query: 55 HIKTVCDAAEKGVRTLTAAAVSGAQPIL-SKLEPQIASASEYAHRGLDKLEENLPILQQP 113
H + EK ++ VSGA+ ++ SK+ + S +D + +
Sbjct: 54 HPEQTAPWTEKELQPSEKQMVSGAKDLVCSKMSRAKDAVSSGVASVVDVAKGVVQGGLDT 113
Query: 114 TEKVLADTKELVSSKVSGAQEMVSSA---------------KDTVATQLSEAVDATRGAV 158
T L TKE+VSS V+GA +M A KDTV+T L+ AV+ +G V
Sbjct: 114 TRSALTGTKEVVSSGVTGAMDMAKGAVQGGLDTSKAVLTGTKDTVSTGLTGAVNVAKGTV 173
Query: 159 QSGVDKTKSVVTGGVQSVMGSRLGQM------VLSGVDT 191
Q+GVD TK+V+TG +V +G + V +GV+T
Sbjct: 174 QAGVDTTKTVLTGTKDTVTTGVMGAVNLAKGTVQTGVET 212
Score = 50.4 bits (119), Expect = 3e-06
Identities = 33/99 (33%), Positives = 53/99 (53%), Gaps = 21/99 (21%)
Query: 114 TEKVLADTKELVSSKVSGA---------------QEMVSSAKDTVATQLSEAVDATRGAV 158
T+ VL TK+ V++ V GA + +++ KD V+T L+ AV+ RG++
Sbjct: 180 TKTVLTGTKDTVTTGVMGAVNLAKGTVQTGVETSKAVLTGTKDAVSTGLTGAVNVARGSI 239
Query: 159 QSGVDKTKSVVTGGVQSVMGSRLGQM------VLSGVDT 191
Q+GVD +K+V+TG +V G M + +GVDT
Sbjct: 240 QTGVDTSKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDT 278
Score = 48.5 bits (114), Expect = 1e-05
Identities = 46/184 (25%), Positives = 87/184 (47%), Gaps = 37/184 (20%)
Query: 34 LISSTCDMVSAAYASTKESYPH-IKTVCDAAE---KGVRTLTAAAVSGAQPILSK-LEPQ 88
++S D+V + + K++ + +V D A+ +G T +A++G + ++S +
Sbjct: 73 MVSGAKDLVCSKMSRAKDAVSSGVASVVDVAKGVVQGGLDTTRSALTGTKEVVSSGVTGA 132
Query: 89 IASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGA---------------Q 133
+ A GLD ++ VL TK+ VS+ ++GA +
Sbjct: 133 MDMAKGAVQGGLDT-----------SKAVLTGTKDTVSTGLTGAVNVAKGTVQAGVDTTK 181
Query: 134 EMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQM------VLS 187
+++ KDTV T + AV+ +G VQ+GV+ +K+V+TG +V G + + +
Sbjct: 182 TVLTGTKDTVTTGVMGAVNLAKGTVQTGVETSKAVLTGTKDAVSTGLTGAVNVARGSIQT 241
Query: 188 GVDT 191
GVDT
Sbjct: 242 GVDT 245
Score = 48.5 bits (114), Expect = 1e-05
Identities = 37/100 (37%), Positives = 50/100 (50%), Gaps = 23/100 (23%)
Query: 114 TEKVLADTKELVSSKVSGAQEMVSSA---------------KDTVATQLSEAVDATRGAV 158
T+ VL TK+ V S V+GA + A KD V+T L+ AV+ +G V
Sbjct: 444 TKIVLTGTKDTVCSGVTGAANVAKGAVQGGLDTTKSVLTGTKDAVSTGLTGAVNVAKGTV 503
Query: 159 QSGVDKTKSVVTG-------GVQSVMGSRLGQMVLSGVDT 191
Q+GVD TK+V+TG GV S + G V G+DT
Sbjct: 504 QTGVDTTKTVLTGTKDTVCSGVTSAVNVAKG-AVQGGLDT 542
Score = 48.1 bits (113), Expect = 2e-05
Identities = 33/99 (33%), Positives = 51/99 (51%), Gaps = 21/99 (21%)
Query: 114 TEKVLADTKELVSSKVSGA---------------QEMVSSAKDTVATQLSEAVDATRGAV 158
T+ VL TK+ VS+ ++GA + +++ KDTV + ++ AV+ +GAV
Sbjct: 477 TKSVLTGTKDAVSTGLTGAVNVAKGTVQTGVDTTKTVLTGTKDTVCSGVTSAVNVAKGAV 536
Query: 159 QSGVDKTKSVVTGGVQSVMGSRLGQ------MVLSGVDT 191
Q G+D TKSVV G ++ G V +GVDT
Sbjct: 537 QGGLDTTKSVVIGTKDTMSTGLTGAANVAKGAVQTGVDT 575
Score = 47.8 bits (112), Expect = 2e-05
Identities = 32/99 (32%), Positives = 50/99 (50%), Gaps = 21/99 (21%)
Query: 114 TEKVLADTKELVSSKVSGA---------------QEMVSSAKDTVATQLSEAVDATRGAV 158
T+ VL TK V S V+GA + MV KDT++T L+ A + +GA+
Sbjct: 345 TKTVLTGTKNTVCSGVTGAVNLAKEAIQGGLDTTKSMVMGTKDTMSTGLTGAANVAKGAM 404
Query: 159 QSGVDKTKSVVTGGVQSVMGSRLGQM------VLSGVDT 191
Q+G++ T+++ TG +V G M + +GVDT
Sbjct: 405 QTGLNTTQNIATGTKDTVCSGVTGAMNLARGTIQTGVDT 443
Score = 47.8 bits (112), Expect = 2e-05
Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 21/99 (21%)
Query: 114 TEKVLADTKELVSSKVSGAQEM---------------VSSAKDTVATQLSEAVDATRGAV 158
T+ + TK+ V S V+GA + ++ KDTV + ++ A + +GAV
Sbjct: 411 TQNIATGTKDTVCSGVTGAMNLARGTIQTGVDTTKIVLTGTKDTVCSGVTGAANVAKGAV 470
Query: 159 QSGVDKTKSVVTGGVQSVMGSRLGQM------VLSGVDT 191
Q G+D TKSV+TG +V G + V +GVDT
Sbjct: 471 QGGLDTTKSVLTGTKDAVSTGLTGAVNVAKGTVQTGVDT 509
Score = 47.4 bits (111), Expect = 3e-05
Identities = 35/99 (35%), Positives = 47/99 (47%), Gaps = 21/99 (21%)
Query: 114 TEKVLADTKELVSSKVSGAQEMVSSA---------------KDTVATQLSEAVDATRGAV 158
T+ VL TK+ V S V+GA + A KD V+T L+ AV +G V
Sbjct: 708 TKTVLTGTKDTVCSGVTGAANVAKGAIQGGLDTTKSVLTGTKDAVSTGLTGAVKLAKGTV 767
Query: 159 QSGVDKTKSVVTGGVQSVMGSRLGQ------MVLSGVDT 191
Q+G+D TK+V+TG +V G V GVDT
Sbjct: 768 QTGMDTTKTVLTGTKDAVCSGVTGAANVAKGAVQMGVDT 806
Score = 47.0 bits (110), Expect = 3e-05
Identities = 33/99 (33%), Positives = 51/99 (51%), Gaps = 21/99 (21%)
Query: 114 TEKVLADTKELVSSKVSGA---------------QEMVSSAKDTVATQLSEAVDATRGAV 158
T+ VL TK+ V S V+ A + +V KDT++T L+ A + +GAV
Sbjct: 510 TKTVLTGTKDTVCSGVTSAVNVAKGAVQGGLDTTKSVVIGTKDTMSTGLTGAANVAKGAV 569
Query: 159 QSGVDKTKSVVTGGVQSVMGSRLGQM------VLSGVDT 191
Q+GVD K+V+TG +V +G + V +G+DT
Sbjct: 570 QTGVDTAKTVLTGTKDTVTTGLVGAVNVAKGTVQTGMDT 608
Score = 46.6 bits (109), Expect = 4e-05
Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 21/99 (21%)
Query: 114 TEKVLADTKELVSSKVSGAQEMVSSA---------------KDTVATQLSEAVDATRGAV 158
T+ + TK + S V+GA ++ A KD V+T L+ AV+ +G V
Sbjct: 840 TQNIATGTKNTLGSGVTGAAKVAKGAVQGGLDTTKSVLTGTKDAVSTGLTGAVNLAKGTV 899
Query: 159 QSGVDKTKSVVTGGVQSVMGSRLGQM------VLSGVDT 191
Q+GVD +K+V+TG +V G + V +GVDT
Sbjct: 900 QTGVDTSKTVLTGTKDTVCSGVTGAVNVAKGTVQTGVDT 938
Score = 46.2 bits (108), Expect = 6e-05
Identities = 29/101 (28%), Positives = 54/101 (53%), Gaps = 21/101 (20%)
Query: 112 QPTEKVLADTKELVSSKVSGA---------------QEMVSSAKDTVATQLSEAVDATRG 156
+ ++ VL TK+ VS+ ++GA + +++ KDTV + ++ A++ +G
Sbjct: 211 ETSKAVLTGTKDAVSTGLTGAVNVARGSIQTGVDTSKTVLTGTKDTVCSGVTGAMNVAKG 270
Query: 157 AVQSGVDKTKSVVTGGVQSVMGSRLGQM------VLSGVDT 191
+Q+GVD +K+V+TG +V G M + +GVDT
Sbjct: 271 TIQTGVDTSKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDT 311
Score = 46.2 bits (108), Expect = 6e-05
Identities = 30/99 (30%), Positives = 51/99 (51%), Gaps = 21/99 (21%)
Query: 114 TEKVLADTKELVSSKVSGAQEM---------------VSSAKDTVATQLSEAVDATRGAV 158
++ VL TK+ V S V+GA + ++ KDTV + ++ A++ +G +
Sbjct: 246 SKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDTSKTVLTGTKDTVCSGVTGAMNVAKGTI 305
Query: 159 QSGVDKTKSVVTGGVQSVMGSRLGQM------VLSGVDT 191
Q+GVD +K+V+TG +V G M + +GVDT
Sbjct: 306 QTGVDTSKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDT 344
Score = 45.1 bits (105), Expect = 1e-04
Identities = 29/99 (29%), Positives = 50/99 (50%), Gaps = 21/99 (21%)
Query: 114 TEKVLADTKELVSSKVSGAQEM---------------VSSAKDTVATQLSEAVDATRGAV 158
++ VL TK+ V S V+GA + ++ KDTV + ++ A++ +G +
Sbjct: 279 SKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDTSKTVLTGTKDTVCSGVTGAMNVAKGTI 338
Query: 159 QSGVDKTKSVVTGGVQSVMGSRLG------QMVLSGVDT 191
Q+GVD TK+V+TG +V G + + G+DT
Sbjct: 339 QTGVDTTKTVLTGTKNTVCSGVTGAVNLAKEAIQGGLDT 377
Score = 44.7 bits (104), Expect = 2e-04
Identities = 38/149 (25%), Positives = 62/149 (41%), Gaps = 32/149 (21%)
Query: 64 EKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKE 123
+ GV T + S + + A E GLD T+ ++ TK+
Sbjct: 339 QTGVDTTKTVLTGTKNTVCSGVTGAVNLAKEAIQGGLDT-----------TKSMVMGTKD 387
Query: 124 LVSSKVSGA---------------QEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSV 168
+S+ ++GA Q + + KDTV + ++ A++ RG +Q+GVD TK V
Sbjct: 388 TMSTGLTGAANVAKGAMQTGLNTTQNIATGTKDTVCSGVTGAMNLARGTIQTGVDTTKIV 447
Query: 169 VTGGVQSVMGSRLGQ------MVLSGVDT 191
+TG +V G V G+DT
Sbjct: 448 LTGTKDTVCSGVTGAANVAKGAVQGGLDT 476
Score = 44.7 bits (104), Expect = 2e-04
Identities = 32/96 (33%), Positives = 47/96 (48%), Gaps = 21/96 (21%)
Query: 117 VLADTKELVSSKVSGA---------------QEMVSSAKDTVATQLSEAVDATRGAVQSG 161
VL TK+ V S V+GA Q + + K+T+ + ++ A +GAVQ G
Sbjct: 810 VLTGTKDTVCSGVTGAANVAKGAVQTGLKTTQNIATGTKNTLGSGVTGAAKVAKGAVQGG 869
Query: 162 VDKTKSVVTGGVQSVMGSRLGQM------VLSGVDT 191
+D TKSV+TG +V G + V +GVDT
Sbjct: 870 LDTTKSVLTGTKDAVSTGLTGAVNLAKGTVQTGVDT 905
Score = 44.3 bits (103), Expect = 2e-04
Identities = 22/50 (44%), Positives = 33/50 (66%)
Query: 122 KELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTG 171
K V + V A+ +++ KDTV T L AV+ +G VQ+G+D TK+V+TG
Sbjct: 566 KGAVQTGVDTAKTVLTGTKDTVTTGLVGAVNVAKGTVQTGMDTTKTVLTG 615
Score = 44.3 bits (103), Expect = 2e-04
Identities = 25/76 (32%), Positives = 42/76 (55%), Gaps = 6/76 (7%)
Query: 122 KELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRL 181
K V + V + +++ KDTV + ++ A + +GA+Q G+D TKSV+TG +V
Sbjct: 698 KGTVQTSVDTTKTVLTGTKDTVCSGVTGAANVAKGAIQGGLDTTKSVLTGTKDAVSTGLT 757
Query: 182 GQM------VLSGVDT 191
G + V +G+DT
Sbjct: 758 GAVKLAKGTVQTGMDT 773
Score = 44.3 bits (103), Expect = 2e-04
Identities = 30/98 (30%), Positives = 51/98 (52%), Gaps = 21/98 (21%)
Query: 114 TEKVLADTKELVSSKVSGA---------------QEMVSSAKDTVATQLSEAVDATRGAV 158
T+ VL TK+ VS+ ++GA + +++ KDTV + ++ AV+ +G V
Sbjct: 873 TKSVLTGTKDAVSTGLTGAVNLAKGTVQTGVDTSKTVLTGTKDTVCSGVTGAVNVAKGTV 932
Query: 159 QSGVDKTKSVVTGGVQSVMGSRLGQM------VLSGVD 190
Q+GVD K+V++G +V G + V +GVD
Sbjct: 933 QTGVDTAKTVLSGAKDAVTTGVTGAVNVAKGTVQTGVD 970
Score = 42.7 bits (99), Expect = 6e-04
Identities = 23/61 (37%), Positives = 34/61 (55%)
Query: 122 KELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRL 181
K + V A+ +++ KDTV T L AV+ +G VQ+ VD TK+V+TG +V
Sbjct: 665 KGAAQTGVDTAKTVLTGTKDTVTTGLMGAVNVAKGTVQTSVDTTKTVLTGTKDTVCSGVT 724
Query: 182 G 182
G
Sbjct: 725 G 725
Score = 42.4 bits (98), Expect = 8e-04
Identities = 40/161 (24%), Positives = 64/161 (39%), Gaps = 24/161 (14%)
Query: 35 ISSTCDMVSAAYASTKESYPHIKTVCDAAEKGVRTLTAAAVSGAQPILSKLEPQIASASE 94
+ ++ D TK+ TVC G + A+ G + A
Sbjct: 701 VQTSVDTTKTVLTGTKD------TVCSGVT-GAANVAKGAIQGGLDTTKSVLTGTKDAVS 753
Query: 95 YAHRGLDKLEENLPILQQPTEK-VLADTKELVSSKVSGAQEMVSSA-------------- 139
G KL + T K VL TK+ V S V+GA + A
Sbjct: 754 TGLTGAVKLAKGTVQTGMDTTKTVLTGTKDAVCSGVTGAANVAKGAVQMGVDTAKTVLTG 813
Query: 140 -KDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGS 179
KDTV + ++ A + +GAVQ+G+ T+++ T G ++ +GS
Sbjct: 814 TKDTVCSGVTGAANVAKGAVQTGLKTTQNIAT-GTKNTLGS 853
Score = 42.4 bits (98), Expect = 8e-04
Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 15/84 (17%)
Query: 114 TEKVLADTKELVSSKVSGAQEM---------------VSSAKDTVATQLSEAVDATRGAV 158
T+ VL TK+ VS+ ++GA ++ ++ KD V + ++ A + +GAV
Sbjct: 741 TKSVLTGTKDAVSTGLTGAVKLAKGTVQTGMDTTKTVLTGTKDAVCSGVTGAANVAKGAV 800
Query: 159 QSGVDKTKSVVTGGVQSVMGSRLG 182
Q GVD K+V+TG +V G
Sbjct: 801 QMGVDTAKTVLTGTKDTVCSGVTG 824
Score = 41.6 bits (96), Expect = 0.001
Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 21/99 (21%)
Query: 114 TEKVLADTKELVSSKVSGA---------------QEMVSSAKDTVATQLSEAVDATRGAV 158
T+ VL TK+ + S V+ A Q + + K+T + ++ AV+ +GA
Sbjct: 609 TKTVLTGTKDTIYSGVTSAVNVAKGAVQTGLKTTQNIATGTKNTFGSGVTSAVNVAKGAA 668
Query: 159 QSGVDKTKSVVTGGVQSVMGSRLGQM------VLSGVDT 191
Q+GVD K+V+TG +V +G + V + VDT
Sbjct: 669 QTGVDTAKTVLTGTKDTVTTGLMGAVNVAKGTVQTSVDT 707
Score = 39.7 bits (91), Expect = 0.005
Identities = 29/119 (24%), Positives = 54/119 (45%), Gaps = 20/119 (16%)
Query: 117 VLADTKELVSSKVSGA---------------QEMVSSAKDTVATQLSEAVDATRGAVQSG 161
VL TK+ V++ + GA + +++ KDT+ + ++ AV+ +GAVQ+G
Sbjct: 579 VLTGTKDTVTTGLVGAVNVAKGTVQTGMDTTKTVLTGTKDTIYSGVTSAVNVAKGAVQTG 638
Query: 162 VDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDG 220
+ T+++ TG + G V S V+ G ++ D + + T L G
Sbjct: 639 LKTTQNIATG-----TKNTFGSGVTSAVNVAKGAAQTGVDTAKTVLTGTKDTVTTGLMG 692
Score = 37.7 bits (86), Expect = 0.021
Identities = 23/73 (31%), Positives = 39/73 (53%), Gaps = 15/73 (20%)
Query: 114 TEKVLADTKELVSSKVSGAQEM---------------VSSAKDTVATQLSEAVDATRGAV 158
++ VL TK+ V S V+GA + ++ K+TV + ++ AV+ + A+
Sbjct: 312 SKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDTTKTVLTGTKNTVCSGVTGAVNLAKEAI 371
Query: 159 QSGVDKTKSVVTG 171
Q G+D TKS+V G
Sbjct: 372 QGGLDTTKSMVMG 384
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 47.8 bits (112), Expect = 2e-05
Identities = 90/440 (20%), Positives = 166/440 (37%), Gaps = 109/440 (24%)
Query: 38 TCDMVSAAYASTKESYPHIKTVCDAAEKGVRTLT-------------AAAVSGAQPILSK 84
T D S A T+ + H KT+ A RTL+ A+A SG Q + +
Sbjct: 2257 TRDQASQLLAGTEATLGHAKTLLAAIRAVDRTLSELMSQTGHLGLANASAPSGEQLLRTL 2316
Query: 85 LE---------------PQIASASEY--AHRGLDKLEENLPILQQPTEKVLADTKELVSS 127
E PQ A+ +E A R L +++E L L + + + T++ ++
Sbjct: 2317 AEVERLLWEMRARDLGAPQAAAEAELAAAQRLLARVQEQLSSLWEENQALATQTRDRLAQ 2376
Query: 128 KVSGAQEMVSSAKDTVATQLSEAVDATRGA----------VQSGVDKTKSVVTGGVQSVM 177
+G ++ + L+ AVDATR A ++ + + + +
Sbjct: 2377 HEAGLMDLREA--------LNRAVDATREAQELNSRNQERLEEALQRKQELSRDNATLQA 2428
Query: 178 GSRLGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQR------- 230
+ L+ V +L + L EL R+A SLDG +Q+ +
Sbjct: 2429 TLHAARDTLASVFRLL--------HSLDQAKEELERLAASLDGARTPLLQRMQTFSPAGS 2480
Query: 231 ------QEQSYFVRLGSLS------------ERLRQ------HAYEHSLGKLRATKQRAQ 266
+++ +LG L+ +RL Q +AY L ++A + A
Sbjct: 2481 KLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDAAG 2540
Query: 267 EALLQLSQALSLMETVKQG--------------VDQKLVEGQEKLHQMWLSWNQKQLQGP 312
+AL Q + + V+QG +++ +++ Q++L +W + + Q
Sbjct: 2541 QALQQADHTWATV--VRQGLVDRAQQLLANSTALEEAMLQEQQRLGLVWAALQGARTQLR 2598
Query: 313 EKEPPKPE-----QVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQARRQVE 367
+ K + Q L M D + A ++ + Q T V+ Q+Q + VE
Sbjct: 2599 DVRAKKDQLEAHIQAAQAMLAMDTDETSKKIAHAKAVAAEAQDTATRVQSQLQAMQENVE 2658
Query: 368 DLQATFSSIHSFQDLSSSIL 387
Q + + QDL ++L
Sbjct: 2659 RWQGQYEGLRG-QDLGQAVL 2677
Score = 38.5 bits (88), Expect = 0.012
Identities = 70/332 (21%), Positives = 139/332 (41%), Gaps = 42/332 (12%)
Query: 82 LSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKV--LADTKELVSSKVSGAQEMVSSA 139
L++ E + E +R +D E + + E++ K+ +S + Q + +A
Sbjct: 2374 LAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEALQRKQELSRDNATLQATLHAA 2433
Query: 140 KDTVAT--QLSEAVDATRGAVQ---SGVDKTKSVVTGGVQ--SVMGSRL----------- 181
+DT+A+ +L ++D + ++ + +D ++ + +Q S GS+L
Sbjct: 2434 RDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFSPAGSKLRLVEAAEAHAQ 2493
Query: 182 --GQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVAS---VQQQRQEQSYF 236
GQ+ L+ +L +++ +RI ++ + A+ +QQ +
Sbjct: 2494 QLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDAAGQALQQADHTWATV 2553
Query: 237 VRLGSLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEK 296
VR G L +R +Q L A +EA+LQ Q L L+ QG +L + + K
Sbjct: 2554 VRQG-LVDRAQQ---------LLANSTALEEAMLQEQQRLGLVWAALQGARTQLRDVRAK 2603
Query: 297 LHQMWLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVK 356
Q+ + +Q + S+ + + +A + Q T T + S +Q + NV+
Sbjct: 2604 KDQL-----EAHIQAAQAMLAMDTDETSKKIAHAKAVAAEAQDTATRVQSQLQAMQENVE 2658
Query: 357 D-QVQQARRQVEDL-QATFSSIHSFQDLSSSI 386
Q Q + +DL QA + HS L ++
Sbjct: 2659 RWQGQYEGLRGQDLGQAVLDAGHSVSTLEKTL 2690
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 47.4 bits (111), Expect = 3e-05
Identities = 62/295 (21%), Positives = 117/295 (39%), Gaps = 34/295 (11%)
Query: 88 QIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAKDTVATQL 147
++ SA+E R L +L + QQ E++ + + K+ AQE + +D + +
Sbjct: 593 RLRSANELLSREKSNLAHSLQVAQQQAEELRQERE-----KLQAAQEELRRQRDRLEEEQ 647
Query: 148 SEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEEWADNHLPLT 207
+AV Q G + + Q L G +VL K E + L+
Sbjct: 648 EDAV-------QDGARVRRELERSHRQLEQ--------LEGKRSVLAK--ELVEVREALS 690
Query: 208 DAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYEHSLGKLRATKQRAQE 267
A L R + +VA + + + L R + + + SL KL A + +
Sbjct: 691 RATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQ 750
Query: 268 ALLQLSQALSLMETVKQGVDQK----------LVEGQEKLHQMWLSWN--QKQLQGPEKE 315
L L++ ++ +E K + + E QE+L ++ L ++ L+G +
Sbjct: 751 DKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRV 810
Query: 316 PPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQARRQVEDLQ 370
+ ++ + L R QLQ L + G ++ ++A+RQVE L+
Sbjct: 811 AEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALE 865
Score = 38.9 bits (89), Expect = 0.009
Identities = 36/180 (20%), Positives = 76/180 (42%), Gaps = 16/180 (8%)
Query: 227 QQQRQEQSYFVRLGSLSERLRQHAYEHSLGKLRATKQRAQEALL----QLSQALSLMETV 282
Q QR+++ RL + E L + ++ A +Q E LL + QALSL E+
Sbjct: 1019 QLQREQEELLARLEAEKEELSE--------EIAALQQERDEGLLLAESEKQQALSLKESE 1070
Query: 283 KQGVDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCT 342
K + +KL+ + L + L ++Q + + + + + RD+ Q +
Sbjct: 1071 KTALSEKLMGTRHSLATISLEM-ERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAA 1129
Query: 343 SLGSSIQGLPTNVKD---QVQQARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASARE 399
+ ++ L +D Q R+ E+L+ + +D L +++ ++ ++E
Sbjct: 1130 AHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQE 1189
Score = 33.1 bits (74), Expect = 0.51
Identities = 34/157 (21%), Positives = 75/157 (47%), Gaps = 8/157 (5%)
Query: 260 ATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPKP 319
+ ++ +E L Q +L ++ Q + +L QEK+ +M N+ +L+G ++ +
Sbjct: 1587 SVRRSERERRATLDQVATLERSL-QATESELRASQEKISKM--KANETKLEGDKRRLKEV 1643
Query: 320 -EQVESRALTMF---RDIAQQLQATCTSLGSSIQGLPTNVKDQVQQARRQVEDLQATFSS 375
+ ESR + + R + +LQ + L S + ++D+V +RQV D + +
Sbjct: 1644 LDASESRTVKLELQRRSLEGELQRSRLGL-SDREAQAQALQDRVDSLQRQVADSEVKAGT 1702
Query: 376 IHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNT 412
+ + + LA+ E + R+ + + E +AQ++
Sbjct: 1703 LQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSS 1739
Score = 28.9 bits (63), Expect = 9.5
Identities = 44/217 (20%), Positives = 93/217 (42%), Gaps = 33/217 (15%)
Query: 208 DAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYEHSLGKLRATKQRAQE 267
D L+ + L + + + +R+ ++ ++ +L L+ E + + +K +A E
Sbjct: 1571 DGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANE 1630
Query: 268 ALLQ-----LSQALSLME--TVKQGVDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPE 320
L+ L + L E TVK + ++ +EG+ + ++ LS + Q Q
Sbjct: 1631 TKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQA--------- 1681
Query: 321 QVESRALTMFRDIAQQ------LQATCTSLGSSIQGLPTNVKDQVQQARRQVEDLQATFS 374
++ R ++ R +A LQ T L ++ + + + R E L + +
Sbjct: 1682 -LQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSA 1740
Query: 375 SIHSFQD----LSSSILAQS------RERVASAREAL 401
S++S +D L ++ A +ER+ +AR+AL
Sbjct: 1741 SLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQAL 1777
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 47.4 bits (111), Expect = 3e-05
Identities = 78/361 (21%), Positives = 151/361 (41%), Gaps = 51/361 (14%)
Query: 79 QPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKV---LADTKELVSSK------V 129
Q I KL+ + S E A + L+E L + + E++ LAD + VS++ V
Sbjct: 1479 QQIQRKLQAALISRKE-ALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTV 1537
Query: 130 SGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGV 189
G ++ +D + T++ ++ + ++ S + K + G + +L + + S
Sbjct: 1538 LGRLALLQEERDKLITEMDRSLLENQ-SLSSSCESLKLALEGLTEDK--EKLVKEIESLK 1594
Query: 190 DTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQH 249
+ + +S EW + H L L ++ S + +R + + E +RQ
Sbjct: 1595 SSKIAESTEWQEKHKELQK----EYEILLQSYENVSNEAERIQH--------VVEAVRQE 1642
Query: 250 AYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQMWLSWNQKQL 309
E GKLR+T+ +E QL +A +Q++ E +EK+ + S QK L
Sbjct: 1643 KQE-LYGKLRSTEANKKETEKQLQEA-----------EQEMEEMKEKMRKFAKSKQQKIL 1690
Query: 310 QGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQARRQVEDL 369
+ E+ +V D A++ T S +S +K+++++ + + E L
Sbjct: 1691 ELEEENDRLRAEVHPAG-----DTAKECMETLLSSNAS-------MKEELERVKMEYETL 1738
Query: 370 QATFSSIHSFQDLSSSILAQSRERVAS--AREALDHMVEYVAQNTPVTWLVGPFAPGITE 427
F S+ S +D S + + ++ +++A E T VT PG TE
Sbjct: 1739 SKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETE 1798
Query: 428 K 428
+
Sbjct: 1799 E 1799
Score = 33.5 bits (75), Expect = 0.39
Identities = 77/342 (22%), Positives = 135/342 (39%), Gaps = 41/342 (11%)
Query: 64 EKGVRTLTAAAVSGA--QPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADT 121
+ G ++L+A G Q L +L+ QI H+ + E+NL K +++
Sbjct: 666 QDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNL----DEKAKEISNL 721
Query: 122 KELV------SSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQS 175
+L+ + S A +S +D + +Q+ E T Q K + ++
Sbjct: 722 NQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQ-----VKQLEMNLAEA 776
Query: 176 VMGSRLGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSY 235
RL + D +L + D ++ + LD VQ Q EQS
Sbjct: 777 ERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELD-----DVQLQFSEQST 831
Query: 236 FVRLGSLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQE 295
+R SL +L+ E G R + + +LSQALS E +DQ L+E +
Sbjct: 832 LIR--SLQSQLQNKESEVLEGAERV--RHISSKVEELSQALSQKELEITKMDQLLLEKKR 887
Query: 296 KLHQMWLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGL--PT 353
+ + Q+ ++ K +QV + +M + QL SLG I+ L
Sbjct: 888 DVETL-----QQTIE------EKDQQVTEISFSMTEKMV-QLNEEKFSLGVEIKTLKEQL 935
Query: 354 NVKDQVQQARR-QVEDLQATFSSIHSFQDLSSSILAQSRERV 394
N+ + ++A++ QVE+ S + D S S+E +
Sbjct: 936 NLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEEL 977
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 46.2 bits (108), Expect = 6e-05
Identities = 57/231 (24%), Positives = 94/231 (40%), Gaps = 24/231 (10%)
Query: 183 QMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSL 242
+MV TVLG+ + L T E + G ++QQ +E V G
Sbjct: 704 KMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILG-----LEQQLKETRGLVDGGEA 758
Query: 243 SE-RLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQMW 301
E RLR L +L A KQ+ +EAL + + K+ ++ +L E Q L +
Sbjct: 759 VEARLRD-----KLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLAR-- 811
Query: 302 LSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGS-----------SIQG 350
L Q+ L +E K +V R + + L T L ++Q
Sbjct: 812 LGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQ 871
Query: 351 LPTNVKDQVQQARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREAL 401
L ++D ++ARR+V D Q S + +S L++ ++ + R+AL
Sbjct: 872 LQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQAL 922
Score = 36.2 bits (82), Expect = 0.060
Identities = 64/314 (20%), Positives = 128/314 (40%), Gaps = 28/314 (8%)
Query: 73 AAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGA 132
A + Q L++ + E RG +LEE +L + +++ + +++
Sbjct: 810 ARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQAL 869
Query: 133 QEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTV 192
Q++ + +D E DA R A + K+ +GG+ SRL Q + +
Sbjct: 870 QQLQAQLEDYKEKARREVADAQRQAKDWASEAEKT--SGGL-----SRL-QDEIQRLRQA 921
Query: 193 LGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYE 252
L S+ A+ D EL +A L G + + ++R + +L L E++ + E
Sbjct: 922 LQASQ--AERDTARLDKEL--LAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETE 977
Query: 253 -----HSLGKLRATKQRAQEALLQLSQALSLMETVKQGV--DQKLVEGQEKLHQMWLSWN 305
+++ L R ++ + QL L + +Q + D+ +E Q K + L+ +
Sbjct: 978 LDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASS 1037
Query: 306 Q---------KQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVK 356
+ QL+ + + Q E R T+ + ++L+ L I+ +V
Sbjct: 1038 EGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIEDERQHVN 1097
Query: 357 DQVQQARRQVEDLQ 370
DQ Q +V+ L+
Sbjct: 1098 DQKDQLSLRVKALK 1111
>gi|40538794 coiled-coil domain containing 21 [Homo sapiens]
Length = 762
Score = 45.1 bits (105), Expect = 1e-04
Identities = 50/197 (25%), Positives = 81/197 (41%), Gaps = 46/197 (23%)
Query: 223 VASVQQQRQEQSYFVRLGSLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETV 282
+ QQQ+ +Q ++ SL + + Q E + LR QR AL QL A+ +
Sbjct: 582 IVEKQQQKMDQLRS-QVQSLEQEVAQE--EGTSQALREEAQRRDSALQQLRTAVKELSVQ 638
Query: 283 KQGVDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIA---QQLQA 339
Q + +K + QE L Q PP P+ + AL + +++A Q LQA
Sbjct: 639 NQDLIEKNLTLQEHLRQ-----------AQPGSPPSPDTAQL-ALELHQELASCLQDLQA 686
Query: 340 TCTSLGSSIQGLPTNVK---------------------------DQVQQARRQVEDLQAT 372
C+ + QG N+ ++VQQ RR +EDL+ T
Sbjct: 687 VCSIVTQRAQGHDPNLSLLLGIHSAQHPETQLDLQKPDVIKRKLEEVQQLRRDIEDLRTT 746
Query: 373 FSSIHSFQDLSSSILAQ 389
S ++ QD+ + + Q
Sbjct: 747 MSDRYA-QDMGENCVTQ 762
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 43.5 bits (101), Expect = 4e-04
Identities = 47/197 (23%), Positives = 78/197 (39%), Gaps = 19/197 (9%)
Query: 227 QQQRQEQSYFVRLGSLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGV 286
Q+Q Q+Q + L + L+Q + +L+ Q+A LQ L E ++Q
Sbjct: 232 QEQLQQQQQLLLLQQQGQ-LQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQ 290
Query: 287 DQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGS 346
Q+L++ Q++ Q Q+QLQ P EP + E+VE + + Q+L+ L
Sbjct: 291 QQQLLQQQQEQLQ------QQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQEL-- 342
Query: 347 SIQGLPTNVKDQVQQARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVE 406
++ Q+ RQ E Q Q L + Q ++ + VE
Sbjct: 343 ----------ERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVE 392
Query: 407 YVAQNTPVTWLVGPFAP 423
AQ V + P P
Sbjct: 393 LGAQQQEVQLELTPVQP 409
Score = 31.6 bits (70), Expect = 1.5
Identities = 34/144 (23%), Positives = 65/144 (45%), Gaps = 12/144 (8%)
Query: 227 QQQRQEQSYFVRLGSLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGV 286
QQQ Q Q + E+ R + L +A +Q+ + QL Q + + ++Q
Sbjct: 156 QQQLQPQQ-------VQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQ 208
Query: 287 DQ----KLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCT 342
+Q +L++ QE+L Q Q+QLQ ++ +Q + + + + AQ Q
Sbjct: 209 EQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLE 268
Query: 343 SLGSSI-QGLPTNVKDQVQQARRQ 365
+ + Q L ++Q+QQ ++Q
Sbjct: 269 QQQAQLQQQLLLQQQEQLQQQQQQ 292
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 43.5 bits (101), Expect = 4e-04
Identities = 95/426 (22%), Positives = 162/426 (38%), Gaps = 99/426 (23%)
Query: 50 KESYPHIKTVCDAAEKGVRTLTAAAVSGAQPILSK---LEPQIASA----------SEYA 96
+E H++ + DA + LT Q L K LE ++++A +E
Sbjct: 328 REFASHLQQLQDALNE----LTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEIL 383
Query: 97 HRGLDKLEENLPILQQ--PTEK--VLADTKELVSSKVSGAQEMVSSAKDTVATQLSEAVD 152
L +LEE+L LQ P EK VL D +L + K QE + A + TQL V+
Sbjct: 384 QGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLK----QEAATLAANN--TQLQARVE 437
Query: 153 ATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMV------LSGVDTVLGKSEEWADNHLPL 206
+ G + K + G +L ++ +S + + E+ + H
Sbjct: 438 MLE--TERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGAR 495
Query: 207 TDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYEHSLGKLRATKQRAQ 266
A++A + + L + A++QQQ QE L KQ+A+
Sbjct: 496 LTAQVASLTSELTTLN-ATIQQQDQE-------------------------LAGLKQQAK 529
Query: 267 EALLQLSQALSLMETVKQGV--------------DQKLVEGQEKL------HQMWLSWNQ 306
E QL+Q L E QG+ +Q+L E EK H L+
Sbjct: 530 EKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAA 589
Query: 307 KQLQGPEKEP----PKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQA 362
++ + +E + E +E + QQLQ S Q T + + +
Sbjct: 590 EEREASLRERDAALKQLEALEKEKAAKLEILQQQLQ-VANEARDSAQTSVTQAQREKAEL 648
Query: 363 RRQVEDLQATFSSIHSFQDLSSSILAQ-------------SRERVASAREALDHMVEYVA 409
R+VE+LQA + Q + + +A+ +ERVA ++ L ++ +
Sbjct: 649 SRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALK 708
Query: 410 QNTPVT 415
++ VT
Sbjct: 709 ESLKVT 714
>gi|33188443 microfilament and actin filament cross-linker protein
isoform b [Homo sapiens]
Length = 5938
Score = 43.1 bits (100), Expect = 5e-04
Identities = 52/246 (21%), Positives = 105/246 (42%), Gaps = 18/246 (7%)
Query: 83 SKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAKDT 142
+KL P+ +A L + +E LQ+ T + +E V+S + E +AK+
Sbjct: 2124 TKLSPRELTA---LREKLHQAKEQYEALQEETRVAQKELEEAVTSALQQETEKSKAAKEL 2180
Query: 143 VATQLSEAVDATRGAVQSGVDKTKSVVTG--GVQSVMGSRLGQMVLSGVDTVLGKSE--E 198
+ + +DA V S ++T G++ + G+ L + L D +G ++ E
Sbjct: 2181 AENK--KKIDALLDWVTSVGSSGGQLLTNLPGMEQLSGASLEKGALDTTDGYMGVNQAPE 2238
Query: 199 WADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYEHSLGKL 258
D + A + + F +A+ + Q++ + G Q + LG+L
Sbjct: 2239 KLDKQCEMMKARHQELLSQQQNFILAT----QSAQAFLDQHGHNLTPEEQQMLQQKLGEL 2294
Query: 259 RATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPK 318
K++ +L Q L ++T++ + + L + +E + WL ++K+L+ K
Sbjct: 2295 ---KEQYSTSLAQSEAELKQVQTLQDELQKFLQDHKE--FESWLERSEKELENMHKGGSS 2349
Query: 319 PEQVES 324
PE + S
Sbjct: 2350 PETLPS 2355
>gi|33188445 microfilament and actin filament cross-linker protein
isoform a [Homo sapiens]
Length = 5430
Score = 43.1 bits (100), Expect = 5e-04
Identities = 52/246 (21%), Positives = 105/246 (42%), Gaps = 18/246 (7%)
Query: 83 SKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAKDT 142
+KL P+ +A L + +E LQ+ T + +E V+S + E +AK+
Sbjct: 1622 TKLSPRELTA---LREKLHQAKEQYEALQEETRVAQKELEEAVTSALQQETEKSKAAKEL 1678
Query: 143 VATQLSEAVDATRGAVQSGVDKTKSVVTG--GVQSVMGSRLGQMVLSGVDTVLGKSE--E 198
+ + +DA V S ++T G++ + G+ L + L D +G ++ E
Sbjct: 1679 AENK--KKIDALLDWVTSVGSSGGQLLTNLPGMEQLSGASLEKGALDTTDGYMGVNQAPE 1736
Query: 199 WADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYEHSLGKL 258
D + A + + F +A+ + Q++ + G Q + LG+L
Sbjct: 1737 KLDKQCEMMKARHQELLSQQQNFILAT----QSAQAFLDQHGHNLTPEEQQMLQQKLGEL 1792
Query: 259 RATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPK 318
K++ +L Q L ++T++ + + L + +E + WL ++K+L+ K
Sbjct: 1793 ---KEQYSTSLAQSEAELKQVQTLQDELQKFLQDHKE--FESWLERSEKELENMHKGGSS 1847
Query: 319 PEQVES 324
PE + S
Sbjct: 1848 PETLPS 1853
>gi|71773110 apolipoprotein A-IV precursor [Homo sapiens]
Length = 396
Score = 41.6 bits (96), Expect = 0.001
Identities = 61/304 (20%), Positives = 120/304 (39%), Gaps = 26/304 (8%)
Query: 79 QPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSS 138
+ I +LE A +A+ K+ +NL LQQ E + VS++ + ++
Sbjct: 100 EEIGKELEELRARLLPHANEVSQKIGDNLRELQQRLEPYADQLRTQVSTQAEQLRRQLTP 159
Query: 139 AKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEE 198
+ L E D+ + +++ D+ K+ + V+ + G RL + EE
Sbjct: 160 YAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKG-RLTPYADEFKVKIDQTVEE 218
Query: 199 WADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQH---AYEHSL 255
+ P ++ L+G + Q ++ + R+ + +E LRQ E
Sbjct: 219 LRRSLAPYAQDTQEKLNHQLEGL---TFQMKKNAEELKARISASAEELRQRLAPLAEDVR 275
Query: 256 GKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQMWLSWNQKQLQGPE-- 313
G LR + Q++L +L L DQ++ E + ++ ++N+ +Q E
Sbjct: 276 GNLRGNTEGLQKSLAELGGHL----------DQQVEEFRRRVEPYGENFNKALVQQMEQL 325
Query: 314 --KEPPKPEQVESRALTMFRDIAQQLQATCTSL-----GSSIQGLPTNVKDQVQQARRQV 366
K P VE + +D+ ++ + ++ LP + Q QQ +Q
Sbjct: 326 RQKLGPHAGDVEGHLSFLEKDLRDKVNSFFSTFKEKESQDKTLSLPELEQQQEQQQEQQQ 385
Query: 367 EDLQ 370
E +Q
Sbjct: 386 EQVQ 389
Score = 30.0 bits (66), Expect = 4.3
Identities = 37/159 (23%), Positives = 69/159 (43%), Gaps = 18/159 (11%)
Query: 229 QRQEQSYFVRLGSLSERLRQHAYE------HSLGKLRAT-KQRAQEALLQLSQALSLMET 281
QR E+ SL LR HA E ++ +L+ A E +++ Q + E
Sbjct: 162 QRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTV---EE 218
Query: 282 VKQGVDQKLVEGQEKL-HQM-----WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQ 335
+++ + + QEKL HQ+ + N ++L+ + E++ R + D+
Sbjct: 219 LRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKA--RISASAEELRQRLAPLAEDVRG 276
Query: 336 QLQATCTSLGSSIQGLPTNVKDQVQQARRQVEDLQATFS 374
L+ L S+ L ++ QV++ RR+VE F+
Sbjct: 277 NLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFN 315
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 41.6 bits (96), Expect = 0.001
Identities = 59/315 (18%), Positives = 131/315 (41%), Gaps = 26/315 (8%)
Query: 98 RGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGA 157
RG + L NL +Q E+ +TK+ +SS++ + +S K + ++ + TR
Sbjct: 810 RGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNL 869
Query: 158 VQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEEWADNHLPLTDAELARI--- 214
+D + + T ++ + +++ + + + ++ + + R
Sbjct: 870 DVQLLDTKRQLDT---ETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKG 926
Query: 215 --ATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYEHSLGKLRATKQRAQEALLQL 272
+ D D+ S +Q +EQ + L ERL+ ++ + +A +E+L +
Sbjct: 927 QPSNKEDVDDLVSQLRQTEEQ-----VNDLKERLKTST--SNVEQYQAMVTSLEESLNKE 979
Query: 273 SQALSLMETVKQGVDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQVESRALTMFRD 332
Q + E V++ ++ +L E E Q+ +K+L EKE + + + RA+
Sbjct: 980 KQ---VTEEVRKNIEVRLKESAEFQTQL-----EKKLMEVEKEKQELQDDKRRAIESMEQ 1031
Query: 333 IAQQLQATCTSLGSSIQGL---PTNVKDQVQQARRQVEDLQATFSSIHSFQDLSSSILAQ 389
+L+ T +S+ + +Q + QQARR ++ + + + A
Sbjct: 1032 QLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAA 1091
Query: 390 SRERVASAREALDHM 404
E + +A+E + M
Sbjct: 1092 DVEALQAAKEQVSKM 1106
Score = 35.8 bits (81), Expect = 0.078
Identities = 84/401 (20%), Positives = 153/401 (38%), Gaps = 50/401 (12%)
Query: 31 SMPLISSTCDMVSAAYASTKESYPHIKTVCDAAEKGVRTLTAA-----AVSGAQPILSKL 85
++PL +S+ D VS A ST + +TV A V T A A+ Q I
Sbjct: 625 AIPLHASSLDDVSLA--STPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQEIFENY 682
Query: 86 EPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAKDTVAT 145
+ + A + + L+KL+E + L+ K+ + + S + Q+ V + + T
Sbjct: 683 KKEKAENEKIQNEQLEKLQEQVTDLRSQNTKI-STQLDFASKRYEMLQDNVEGYRREI-T 740
Query: 146 QLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEEWADNHLP 205
L E Q K + ++ Q + G+ V L K +E L
Sbjct: 741 SLHERNQKLTATTQ----KQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEM----LK 792
Query: 206 LTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLS---ERLRQHAYEHSLGKLRATK 262
L++ L++ SL + +QR + L ++ ER + ++ +
Sbjct: 793 LSEVRLSQQRESL-------LAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLE 845
Query: 263 QRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQV 322
+L + T+ + +D +L++ + +L + L KE K Q
Sbjct: 846 HEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLD------TETNLHLNTKELLKNAQK 899
Query: 323 ESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKD------QVQQARRQVEDLQATFSSI 376
E L ++Q S + +G P+N +D Q++Q QV DL+ +
Sbjct: 900 EIATLKQHLS-NMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKT- 957
Query: 377 HSFQDLSSSILAQSRERVASAREALD---HMVEYVAQNTPV 414
S+S + Q + V S E+L+ + E V +N V
Sbjct: 958 ------STSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEV 992
Score = 30.0 bits (66), Expect = 4.3
Identities = 75/352 (21%), Positives = 133/352 (37%), Gaps = 49/352 (13%)
Query: 89 IASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAKDTVATQLS 148
I+S+SE + L N+ LQQ +++L +EL ++ QE SS + +L
Sbjct: 526 ISSSSEVISQHLVSYR-NIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLE 584
Query: 149 EAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEEWADNHLPLTD 208
A+ ++ + SR QM L VD+++ + + + T
Sbjct: 585 SALTE-------------------LEQLRKSRQHQMQL--VDSIVRQRDMYRILLSQTTG 623
Query: 209 AELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYEHSLGKLRATKQRAQEA 268
+ A+SLD +AS ++ S S+ + A + A + +A A
Sbjct: 624 VAIPLHASSLDDVSLASTPKR----------PSTSQTVSTPAPVPVIESTEAIEAKA--A 671
Query: 269 LLQLSQALSLMETVKQGVDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQVESRALT 328
L QL + + K ++ E EKL + L+ + S+
Sbjct: 672 LKQLQEIFENYKKEKAENEKIQNEQLEKLQE-----QVTDLRSQNTKISTQLDFASKRYE 726
Query: 329 MFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQARRQVEDLQATFSSIHSFQDLSSSI-- 386
M +D + + TSL Q L + Q Q +DL+ + + + ++
Sbjct: 727 MLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKK 786
Query: 387 ----LAQSRERVASAREALDHMVEYVAQNTPVTWLVGPFAPGITEKAPEEKK 434
L S R++ RE+L + E QN +T L GI E++ E K
Sbjct: 787 EKEMLKLSEVRLSQQRESL--LAEQRGQNLLLTNL--QTIQGILERSETETK 834
Score = 29.6 bits (65), Expect = 5.6
Identities = 69/361 (19%), Positives = 144/361 (39%), Gaps = 52/361 (14%)
Query: 16 VEEPVQQPSVVDRVASMPLISST--CDMVSAAYASTKESYPHIKTVCDAAEKGVRTLTAA 73
+E V+Q + R + L+ + D + + +TKE + A+K + TL
Sbjct: 855 LENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKN-------AQKEIATL--- 904
Query: 74 AVSGAQPILSKLEPQIAS-ASEYAHRGLDKLEENLPILQ---QPTEKVLADTKELVSSKV 129
+ LS +E Q+AS +S+ +G +E++ L + TE+ + D KE + +
Sbjct: 905 -----KQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTST 959
Query: 130 SGAQE---MVSSAKDTV--ATQLSEAVDAT-------RGAVQSGVDKTKSVVTGGVQSVM 177
S ++ MV+S ++++ Q++E V Q+ ++K V Q +
Sbjct: 960 SNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQ 1019
Query: 178 GSRLGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFV 237
+ + + ++ L + ++ + L R +T+L A Q Q +
Sbjct: 1020 DDK--RRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVE 1077
Query: 238 RLGSLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKL 297
L HA + EAL + +S M +V+Q +++ + + +L
Sbjct: 1078 AQNKYERELMLHAAD-------------VEALQAAKEQVSKMASVRQHLEETTQKAESQL 1124
Query: 298 HQMWLSWNQKQLQGPEKEPP---KPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTN 354
+ SW +++ ++ + E +E + + I + S+ +QG P N
Sbjct: 1125 LECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQG-PLN 1183
Query: 355 V 355
V
Sbjct: 1184 V 1184
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 40.8 bits (94), Expect = 0.002
Identities = 43/189 (22%), Positives = 82/189 (43%), Gaps = 23/189 (12%)
Query: 232 EQSYFVRLGSLSERLRQH--AYEHSLGKLRAT-KQRAQEALL---QLSQALSLMETVKQG 285
+Q + L L ++L Q +G+ QR QE ++ QL +A E +Q
Sbjct: 1741 QQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQS 1800
Query: 286 VDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLG 345
+ +L E Q L Q ++L+ ++E + + E R ++ A LQ
Sbjct: 1801 LQSQLDEAQRALAQ-----RDQELEALQQEQQQAQGQEERV----KEKADALQGALEQAH 1851
Query: 346 SSIQGLPTNVKDQVQQARRQVEDLQATFSSIHSFQDLSSSILAQSRERVAS--------A 397
+++ ++D +QARR E+L + + +++ + A+SRE+ + A
Sbjct: 1852 MTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCA 1911
Query: 398 REALDHMVE 406
+A +H VE
Sbjct: 1912 EQAQEHEVE 1920
Score = 35.8 bits (81), Expect = 0.078
Identities = 67/331 (20%), Positives = 128/331 (38%), Gaps = 30/331 (9%)
Query: 65 KGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKEL 124
KG ++ + IL E ++ E+ H L +L++ L Q + + +T L
Sbjct: 1714 KGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHE-LQELKDQLEQQLQGLHRKVGETSLL 1772
Query: 125 VSSKVSGAQEMVSSAKDTVATQLSEAVDA---TRGAVQSGVDKTKSVVTGGVQSVMGSRL 181
+S + QE+V + QL EA + ++QS +D+ + + Q + +
Sbjct: 1773 LSQR---EQEIV-----VLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQ 1824
Query: 182 GQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGS 241
Q G + + + + L L L Q +EQ+ +
Sbjct: 1825 EQQQAQGQEERVKEKADALQGALEQAHMTLKERHGEL---------QDHKEQARRLEEEL 1875
Query: 242 LSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQMW 301
E R A E LG LRA + ++ALL L Q + + + V+ + ++ Q
Sbjct: 1876 AVEGRRVQALEEVLGDLRAESREQEKALLALQQQCA-EQAQEHEVETRALQDSWLQAQAV 1934
Query: 302 LSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQ 361
L ++L+ E E A R A+ LQ +++QG ++ +Q +
Sbjct: 1935 LKERDQELEALRAESQSSRHQEEAA----RARAEALQEALGKAHAALQGKEQHLLEQAEL 1990
Query: 362 ARRQVEDLQATFSSIHSFQDLSSSILAQSRE 392
+R L+A+ +++ + D + Q E
Sbjct: 1991 SR----SLEASTATLQASLDACQAHSRQLEE 2017
Score = 34.7 bits (78), Expect = 0.17
Identities = 67/349 (19%), Positives = 138/349 (39%), Gaps = 56/349 (16%)
Query: 85 LEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKEL------VSSKVSGAQEMVSS 138
L+ Q+ A + ++L LQ+ + +L D +L + S++ +
Sbjct: 969 LQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRL 1028
Query: 139 AKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEE 198
+ V +L E + R +Q +++ K+ +T S+M +VL D++ + +E
Sbjct: 1029 VEQEVQEKLRETQEYNR--IQKELEREKASLT---LSLMEKEQRLLVLQEADSI--RQQE 1081
Query: 199 WADNHLPLTDAE------------------------LARIATSLDGFDVASVQQQRQEQS 234
+ + +A+ LA+ A L+ + + + +Q+ S
Sbjct: 1082 LSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRAS 1141
Query: 235 YFVRLGSLSE-RLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQ----- 288
+ + ++ +LR + E L L A +Q +A Q +Q SL ++Q +
Sbjct: 1142 LWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQ-AQLASLYSALQQALGSVCESR 1200
Query: 289 -KLVEGQEKLHQMW-LSWNQKQLQGPEKEPPKPEQVESRAL-TMFRDIAQQLQATCTSLG 345
+L G + +W L +Q + K P + + A+ + + Q L T
Sbjct: 1201 PELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKT----- 1255
Query: 346 SSIQGLPTNVKDQVQQARRQVEDLQATFSSIHS-FQDLSSSILAQSRER 393
Q ++DQVQ+ ++ D +A S +H+ QDL + E+
Sbjct: 1256 ---QQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEK 1301
Score = 33.9 bits (76), Expect = 0.30
Identities = 67/343 (19%), Positives = 134/343 (39%), Gaps = 25/343 (7%)
Query: 69 TLTAAAVSGAQPILSKLEPQIASASEYAH---RGLDKLEENLPILQQPTEKVLADTKELV 125
TL + ++ + + L Q+A E + + D+ EE L+Q +K+ + L
Sbjct: 389 TLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLA 448
Query: 126 SSKVSGAQEMVSSAKDTVATQLS-EAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQM 184
V E+ S +K+ Q + E + ++ + + V ++
Sbjct: 449 GQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNV------------EL 496
Query: 185 VLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSE 244
L G K E+ + HL + + E R+ L G + Q + + +R S
Sbjct: 497 QLQGDSAQGQKEEQQEELHLAVRERE--RLQEMLMGLEAK--QSESLSELITLREALESS 552
Query: 245 RLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVK---QGVDQKLVEGQEKLHQMW 301
L ++ A RA++++ +LS + + ++T + KL E L
Sbjct: 553 HLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDK 612
Query: 302 LSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQ 361
+ NQ+ LQ E+ ++E A R+ Q A ++ T+++ Q+Q+
Sbjct: 613 VGLNQQLLQLEEENQSVCSRME--AAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQK 670
Query: 362 ARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHM 404
A +LQA I ++ L++SR + +A L+ +
Sbjct: 671 AEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQL 713
Score = 29.3 bits (64), Expect = 7.3
Identities = 70/343 (20%), Positives = 139/343 (40%), Gaps = 53/343 (15%)
Query: 100 LDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAKDTVATQL---------SEA 150
L +L E + LQ + EL + G +E++ +AK+ + Q+ + A
Sbjct: 1315 LMELHETMASLQSRLRRA-----ELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARA 1369
Query: 151 VDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSG---VDTVLGKSEEWADNHLPLT 207
+ G ++ + +S + + V R L + GK+ + L T
Sbjct: 1370 QASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQT 1429
Query: 208 DAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYE------HSLGKLR-- 259
AE +L G + +++QR+ Q + L SL + R + L K R
Sbjct: 1430 LAEREEEVETLRG-QIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSV 1488
Query: 260 ------ATKQRAQEALLQLSQALSL---METVKQGVDQKLVEGQEKLHQMWLSWNQKQLQ 310
A ++R Q+ +Q Q L ET + ++ +L+E EK QM + + Q+Q
Sbjct: 1489 LEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLE-LEKKDQM-IESQRGQVQ 1546
Query: 311 GPEKEPPKPE------QVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQARR 364
+K+ E + + + + ++L+ + ++ L +++++ Q+
Sbjct: 1547 DLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQE--- 1603
Query: 365 QVEDLQATFSSIHSFQDLSSSILAQSRER---VASAREALDHM 404
LQA S IH + S+ + + +ER V S RE ++ +
Sbjct: 1604 ----LQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEEL 1642
Score = 28.9 bits (63), Expect = 9.5
Identities = 82/366 (22%), Positives = 138/366 (37%), Gaps = 34/366 (9%)
Query: 86 EPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKE--------LVSSKVSGAQEMVS 137
+ ++A A E R +LE L Q E + A +E L ++ +E VS
Sbjct: 870 QQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVS 929
Query: 138 SAKDTVATQLSEAVDAT----RGAVQSGVDKTKSVVTGGVQSVM----GSRLGQMVLSGV 189
+ + TQ E DA+ R V K K T G+ L +
Sbjct: 930 LLETLLQTQ-KELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHR 988
Query: 190 DTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQ-EQSYFVRLGSLSERLR- 247
D + EE + L +L + L VA QR EQ +L E R
Sbjct: 989 DDLAALQEE--SSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRI 1046
Query: 248 QHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQMWLSWNQK 307
Q E L + ++ LL L +A S+ + + Q + E Q + Q LS +
Sbjct: 1047 QKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGE--QKELSAQME 1104
Query: 308 QLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQARRQVE 367
L+ KE E+ L + ++L+A+ + Q L ++ Q +A +
Sbjct: 1105 LLRQEVKEK------EADFLAQEAQLLEELEASHITE----QQLRASLWAQEAKAAQLQL 1154
Query: 368 DLQATFSSIHSFQ-DLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGPFAPGIT 426
L++T S + + + AQ++ ++AS AL + V ++ P G AP +
Sbjct: 1155 RLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGGDSAPSVW 1214
Query: 427 EKAPEE 432
P++
Sbjct: 1215 GLEPDQ 1220
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 40.4 bits (93), Expect = 0.003
Identities = 55/257 (21%), Positives = 107/257 (41%), Gaps = 22/257 (8%)
Query: 57 KTVCDAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLE---ENLPILQQP 113
+TV +K ++ + +S A LS LE ++ SA++ A ++K++ E L +
Sbjct: 815 ETVIKELKKSLK-IKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLRK 873
Query: 114 TEKVLADTKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGV 173
EK +T + + + + + + K + +Q ++ RG SG+ S + GG
Sbjct: 874 KEKEFEETMDALQADIDQLEAEKAELKQRLNSQSKRTIEGLRGPPPSGIATLVSGIAGGA 933
Query: 174 ------QSVMGSRL---GQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVA 224
SV G L ++L + + + + L A++ SL VA
Sbjct: 934 IPGQAPGSVPGPGLVKDSPLLLQQISAMRLHISQLQHENSILKGAQMKASLASLPPLHVA 993
Query: 225 SVQQQRQEQ-----SYFVRLGSLSERLRQ-HAYEHSLGKLR---ATKQRAQEALLQLSQA 275
+ + + + + L E L Q + H + R A K + + + Q++Q
Sbjct: 994 KLSHEGPGSELPAGALYRKTSQLLETLNQLSTHTHVVDITRTSPAAKSPSAQLMEQVAQL 1053
Query: 276 LSLMETVKQGVDQKLVE 292
SL +TV++ D+ L E
Sbjct: 1054 KSLSDTVEKLKDEVLKE 1070
Score = 31.2 bits (69), Expect = 1.9
Identities = 70/352 (19%), Positives = 120/352 (34%), Gaps = 92/352 (26%)
Query: 77 GAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVS--GAQE 134
GA P L P + E + LEE L L+ + A KEL K+ QE
Sbjct: 71 GAVPPL----PSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQE 126
Query: 135 MVSSAKDTVAT----------QLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQM 184
S ++ A + EA++A ++ D ++ + M +
Sbjct: 127 WKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAES 186
Query: 185 VLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFD-VASVQQQRQEQSYFVRLGSLS 243
+ V+ + + +E TD E+ + G D AS Q +Q + RL
Sbjct: 187 LQQEVEALKERVDELT------TDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDAL 240
Query: 244 ERLR-------------QHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKL 290
R+R Q E +L +Q+ + +LSQA S ++ +K+ VD L
Sbjct: 241 VRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAAL 300
Query: 291 VEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQG 350
G E++ +M N
Sbjct: 301 --GAEEMVEMLTDRN--------------------------------------------- 313
Query: 351 LPTNVKDQVQQARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALD 402
N++++V++ R V DL+A +++ + +RE RE LD
Sbjct: 314 --LNLEEKVRELRETVGDLEA-------MNEMNDELQENARETELELREQLD 356
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 40.4 bits (93), Expect = 0.003
Identities = 55/257 (21%), Positives = 107/257 (41%), Gaps = 22/257 (8%)
Query: 57 KTVCDAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLE---ENLPILQQP 113
+TV +K ++ + +S A LS LE ++ SA++ A ++K++ E L +
Sbjct: 929 ETVIKELKKSLK-IKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLRK 987
Query: 114 TEKVLADTKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGV 173
EK +T + + + + + + K + +Q ++ RG SG+ S + GG
Sbjct: 988 KEKEFEETMDALQADIDQLEAEKAELKQRLNSQSKRTIEGLRGPPPSGIATLVSGIAGGA 1047
Query: 174 ------QSVMGSRL---GQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVA 224
SV G L ++L + + + + L A++ SL VA
Sbjct: 1048 IPGQAPGSVPGPGLVKDSPLLLQQISAMRLHISQLQHENSILKGAQMKASLASLPPLHVA 1107
Query: 225 SVQQQRQEQ-----SYFVRLGSLSERLRQ-HAYEHSLGKLR---ATKQRAQEALLQLSQA 275
+ + + + + L E L Q + H + R A K + + + Q++Q
Sbjct: 1108 KLSHEGPGSELPAGALYRKTSQLLETLNQLSTHTHVVDITRTSPAAKSPSAQLMEQVAQL 1167
Query: 276 LSLMETVKQGVDQKLVE 292
SL +TV++ D+ L E
Sbjct: 1168 KSLSDTVEKLKDEVLKE 1184
Score = 31.2 bits (69), Expect = 1.9
Identities = 70/352 (19%), Positives = 120/352 (34%), Gaps = 92/352 (26%)
Query: 77 GAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVS--GAQE 134
GA P L P + E + LEE L L+ + A KEL K+ QE
Sbjct: 185 GAVPPL----PSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQE 240
Query: 135 MVSSAKDTVAT----------QLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQM 184
S ++ A + EA++A ++ D ++ + M +
Sbjct: 241 WKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAES 300
Query: 185 VLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFD-VASVQQQRQEQSYFVRLGSLS 243
+ V+ + + +E TD E+ + G D AS Q +Q + RL
Sbjct: 301 LQQEVEALKERVDELT------TDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDAL 354
Query: 244 ERLR-------------QHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKL 290
R+R Q E +L +Q+ + +LSQA S ++ +K+ VD L
Sbjct: 355 VRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAAL 414
Query: 291 VEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQG 350
G E++ +M N
Sbjct: 415 --GAEEMVEMLTDRN--------------------------------------------- 427
Query: 351 LPTNVKDQVQQARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALD 402
N++++V++ R V DL+A +++ + +RE RE LD
Sbjct: 428 --LNLEEKVRELRETVGDLEA-------MNEMNDELQENARETELELREQLD 470
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 39.7 bits (91), Expect = 0.005
Identities = 51/231 (22%), Positives = 91/231 (39%), Gaps = 15/231 (6%)
Query: 206 LTDAELARIATSLDGFDVASVQQQRQE-----QSYFVRLGSLSERLRQHAYEHSLG--KL 258
L+ +LA+ L G + + QQQ+Q+ Q L L + L H+ + L +
Sbjct: 3835 LSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPM 3894
Query: 259 RATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPK 318
+ +Q Q+ LQ Q L + + Q+L + Q + Q Q+Q Q +++ +
Sbjct: 3895 GSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQ 3954
Query: 319 PEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQARRQVEDLQATFSSIHS 378
+Q + + F+ QQ Q + ++ + QV FSS +
Sbjct: 3955 LQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGA 4014
Query: 379 FQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGPFAPGITEKA 429
L ++L +E + +D V A P T GP A G T ++
Sbjct: 4015 ---LGPTLLLTGKE-----QNTVDPAVSSEATEGPSTHQGGPLAIGTTPES 4057
>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
sapiens]
Length = 1133
Score = 37.7 bits (86), Expect = 0.021
Identities = 44/208 (21%), Positives = 87/208 (41%), Gaps = 32/208 (15%)
Query: 231 QEQSYFVRLGSLSERLRQH--AYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQ 288
QE Y + L + + +H +Y LG+L ++ ++ +L+L + + + D+
Sbjct: 132 QEDIYEKPMNELDKVVEKHKESYRRILGQLLVAEKSRRQTILELEEEKRKHKEYMEKSDE 191
Query: 289 KLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQVES--RALTMFRDIA-------QQLQA 339
+ +++ ++ +Q+ EKE K ++V + LT + A Q+L A
Sbjct: 192 FICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTKLKSFALMVVDEQQRLTA 251
Query: 340 TCTSLGSSIQGLPTNVKD--------------QVQQARRQVEDLQATFSSIHSFQDLSSS 385
T IQ L TN K+ + Q+A R ++LQ + H QD +
Sbjct: 252 QLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMA 311
Query: 386 ILA-------QSRERVASAREALDHMVE 406
L Q ++++A+ +D + E
Sbjct: 312 KLTNEDSQNRQLQQKLAALSRQIDELEE 339
>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
sapiens]
Length = 1135
Score = 37.7 bits (86), Expect = 0.021
Identities = 44/208 (21%), Positives = 87/208 (41%), Gaps = 32/208 (15%)
Query: 231 QEQSYFVRLGSLSERLRQH--AYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQ 288
QE Y + L + + +H +Y LG+L ++ ++ +L+L + + + D+
Sbjct: 132 QEDIYEKPMNELDKVVEKHKESYRRILGQLLVAEKSRRQTILELEEEKRKHKEYMEKSDE 191
Query: 289 KLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQVES--RALTMFRDIA-------QQLQA 339
+ +++ ++ +Q+ EKE K ++V + LT + A Q+L A
Sbjct: 192 FICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTKLKSFALMVVDEQQRLTA 251
Query: 340 TCTSLGSSIQGLPTNVKD--------------QVQQARRQVEDLQATFSSIHSFQDLSSS 385
T IQ L TN K+ + Q+A R ++LQ + H QD +
Sbjct: 252 QLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMA 311
Query: 386 ILA-------QSRERVASAREALDHMVE 406
L Q ++++A+ +D + E
Sbjct: 312 KLTNEDSQNRQLQQKLAALSRQIDELEE 339
>gi|156938343 talin 2 [Homo sapiens]
Length = 2542
Score = 37.4 bits (85), Expect = 0.027
Identities = 84/384 (21%), Positives = 148/384 (38%), Gaps = 82/384 (21%)
Query: 30 ASMPLISSTCDMVSAAY--ASTKESYPHIKTVCDAAEKGVRTLTAAAVSGA--QPILSKL 85
A+ L ST MV AA A+ E+ + + +AAE G+R T AA A + I+++L
Sbjct: 862 AAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAE-GLRVATNAAAQNAIKKKIVNRL 920
Query: 86 EPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAKDTVAT 145
E A+ A T+ + A VS+K AQ+ + + VA
Sbjct: 921 EVAAKQAAAAA-----------------TQTIAASQNAAVSNKNPAAQQQLVQSCKAVAD 963
Query: 146 QLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEEWADNHLP 205
+ + V RG+ D LS ++ S+ +
Sbjct: 964 HIPQLVQGVRGSQAQAED----------------------LSAQLALIISSQNFLQPGSK 1001
Query: 206 LTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYEHSLGKLRATKQRA 265
+ + A + T D Q+ ++L ++ L SL +LR Q+A
Sbjct: 1002 MVSSAKAAVPTVSD-------------QAAAMQLSQCAKNLAT-----SLAELRTASQKA 1043
Query: 266 QEAL--LQLSQALSLMETVKQGV-DQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQV 322
EA +++ AL+ ++T+K + D K+ + +L K L G E + +
Sbjct: 1044 HEACGPMEIDSALNTVQTLKNELQDAKMAAVESQL---------KPLPGETLE-KCAQDL 1093
Query: 323 ESRALTMFRDIAQQLQATCTSLGSS-IQGLPTNVKDQ----VQQARRQVEDLQATFSSIH 377
S + + +AQ L TC + G+ G+ Q + QA R V ++ H
Sbjct: 1094 GSTSKAVGSSMAQLL--TCAAQGNEHYTGVAARETAQALKTLAQAARGVAASTTDPAAAH 1151
Query: 378 SFQDLSSSILAQSRERVASAREAL 401
+ D + ++ S + A++AL
Sbjct: 1152 AMLDSARDVMEGSAMLIQEAKQAL 1175
Score = 34.3 bits (77), Expect = 0.23
Identities = 37/143 (25%), Positives = 69/143 (48%), Gaps = 10/143 (6%)
Query: 40 DMVSAAYASTKESYPHIKTVCDAAEKGVRT-LTAA-AVSGAQPILSKLEPQI--ASASEY 95
+++ A A T E + + A KG + +TAA AVSG I++ L+ I A+A
Sbjct: 1950 ELIECARAVT-EKVSLVLSALQAGNKGTQACITAATAVSG---IIADLDTTIMFATAGTL 2005
Query: 96 AHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAKDTVA--TQLSEAVDA 153
+ ++ + + + ++ DTK LVS S ++ +A+ + A TQL+E V
Sbjct: 2006 NAENSETFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKL 2065
Query: 154 TRGAVQSGVDKTKSVVTGGVQSV 176
++ S +T+ V+ ++ V
Sbjct: 2066 GAASLGSDDPETQVVLINAIKDV 2088
>gi|223029410 talin 1 [Homo sapiens]
Length = 2541
Score = 37.0 bits (84), Expect = 0.035
Identities = 35/149 (23%), Positives = 64/149 (42%), Gaps = 7/149 (4%)
Query: 51 ESYPHIKTVCDAAEKGVRTLTAAAVSGAQPILSKLEPQI--ASASEYAHRGLDKLEENLP 108
E H+ A +G + AA S I++ L+ I A+A G + ++
Sbjct: 1959 EKVSHVLAALQAGNRGTQACITAA-SAVSGIIADLDTTIMFATAGTLNREGTETFADHRE 2017
Query: 109 ILQQPTEKVLADTKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVD--KTK 166
+ + + ++ DTK LV + +++ +A+ +VAT A GA G + +T+
Sbjct: 2018 GILKTAKVLVEDTKVLVQNAAGSQEKLAQAAQSSVATITRLADVVKLGAASLGAEDPETQ 2077
Query: 167 SVVTGGVQSVMGSRLGQMVLSGVDTVLGK 195
V+ V+ V LG ++ S GK
Sbjct: 2078 VVLINAVKDV-AKALGDLI-SATKAAAGK 2104
>gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo
sapiens]
Length = 1002
Score = 36.6 bits (83), Expect = 0.046
Identities = 56/276 (20%), Positives = 108/276 (39%), Gaps = 45/276 (16%)
Query: 89 IASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAKDTVATQLS 148
+AS +Y+ R + +LE L + +K KEL + + E+ + TQ +
Sbjct: 254 LASRLQYSRRRVGELERALSAVSTQQKKADRYNKELTKERDALRLELYKN------TQSN 307
Query: 149 EAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEEWADNHLPLTD 208
E + + ++ +K + +VT + G + + E L +T+
Sbjct: 308 EDLKQEKSELE---EKLRVLVT--------EKAGMQL----------NLEELQKKLEMTE 346
Query: 209 AELARIATSLDGFDVASVQQQRQEQ--SYFVRLGSLSERLRQHAYEHS--LGKLRATKQR 264
L + ++ + D QQ E+ LG + E +RQ E L+
Sbjct: 347 LLLQQFSSRCEAPDANQQLQQAMEERAQLEAHLGQVMESVRQLQMERDKYAENLKGESAM 406
Query: 265 AQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQVES 324
++ + Q+S+ + + K+ ++ E + L +L+ EPP PE
Sbjct: 407 WRQRMQQMSEQVHTLREEKECSMSRVQELETSL---------AELRNQMAEPPPPEPPAG 457
Query: 325 RALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ 360
+ ++ QQLQA L ++GL ++ QVQ
Sbjct: 458 PS-----EVEQQLQAEAEHLRKELEGLAGQLQAQVQ 488
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 36.6 bits (83), Expect = 0.046
Identities = 52/213 (24%), Positives = 93/213 (43%), Gaps = 27/213 (12%)
Query: 190 DTVLGKSEEWADNHLPLTDAE---LARIATSLD-GFDVASVQQQRQEQSYFVRLGSLSER 245
+ ++ K ++ AD L L+ E ++ S + + +QQ QEQ + + R
Sbjct: 446 EKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLR 505
Query: 246 LRQHAYEHSLGKLRATKQRAQ--EALLQLSQA-LSLMETVKQGVDQKLVEGQEKLHQMWL 302
Q+ E L ++ Q+ Q EALLQ S+ +SL+E ++ + K+ G+ + +
Sbjct: 506 EAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVL-- 563
Query: 303 SWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQA 362
QLQ EK EQV QL + S + N+ DQVQ+
Sbjct: 564 ----NQLQ--EKNHTLQEQVT------------QLTEKLKNQSESHKQAQENLHDQVQEQ 605
Query: 363 RRQVEDLQATFSSIHSFQDLSSSILAQSRERVA 395
+ + Q S+ + + +S L +S+E+V+
Sbjct: 606 KAHLRAAQDRVLSLETSVNELNSQLNESKEKVS 638
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 35.8 bits (81), Expect = 0.078
Identities = 56/313 (17%), Positives = 131/313 (41%), Gaps = 45/313 (14%)
Query: 79 QPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSS 138
Q L L +++ + H KLEE L +L+ T+K+ + + + + + Q+ V
Sbjct: 683 QTELESLSSELSEVLKARH----KLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQV-- 736
Query: 139 AKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEE 198
D++ + ++ T A++ +++ +++L D L + +
Sbjct: 737 --DSIIKEHEVSIQRTEKALKDQINQL-----------------ELLLKERDKHLKEHQA 777
Query: 199 WADN---HLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYEHSL 255
+N + ++ EL + + LD F Q ++Y +L L ++L E L
Sbjct: 778 HVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERIL 837
Query: 256 GKLRATKQRAQ--EALLQLSQALSLMETVKQGVDQKLVEGQEKLHQMWLSWNQKQLQGPE 313
+ + AQ + +L ++ + Q ++++ E ++K+ + + K L+
Sbjct: 838 LTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESK-LEDGN 896
Query: 314 KEPPKPEQV----ESRALTM-------FRDIAQQLQATCTSLGSSIQGLPTNVKDQ---V 359
KE + +Q+ E+ L M + Q+L A S+ + T K+Q +
Sbjct: 897 KEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKM 956
Query: 360 QQARRQVEDLQAT 372
++ +++ +++Q T
Sbjct: 957 EKVKQKAKEMQET 969
Score = 34.7 bits (78), Expect = 0.17
Identities = 61/293 (20%), Positives = 122/293 (41%), Gaps = 40/293 (13%)
Query: 101 DKLEEN----LPILQQPTEKVLADTKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRG 156
D+LE L L++ E+ +A K+ + S++ +E ++ ++L+ +
Sbjct: 1627 DRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQERER 1686
Query: 157 AVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIAT 216
V +K KSV + ++++ R + V + + +E AD+ + +I
Sbjct: 1687 EVHILEEKLKSVESSQSETLIVPRSAKNVAAYTE------QEEADSQGCVQKTYEEKI-- 1738
Query: 217 SLDGFDVASVQQQR--QEQSYFVRLGSLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQ 274
SV Q+ +++ R+G E +E + + QE L++L
Sbjct: 1739 --------SVLQRNLTEKEKLLQRVGQEKEETVSSHFE--------MRCQYQERLIKLEH 1782
Query: 275 ALSLMETVKQGVDQKLVEG-QEKLHQMWLSWNQKQLQGPEKEPPKPE-QVESRALTMFRD 332
A KQ DQ ++ QE+L + ++ Q EKE K Q + +F D
Sbjct: 1783 A-----EAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDD 1837
Query: 333 IAQQLQA---TCTSLGSSIQGLPTNVKDQVQQARRQVEDLQATFSSIHSFQDL 382
+ + LQ TC L I+ L + + Q + R ++E+L + + + + Q +
Sbjct: 1838 VQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQM 1890
>gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]
Length = 1044
Score = 35.8 bits (81), Expect = 0.078
Identities = 60/255 (23%), Positives = 106/255 (41%), Gaps = 37/255 (14%)
Query: 68 RTLTAAAVSGAQPILSK-LEPQIASASEYAHRGL---DKLEENLPILQQPTEKVLADTKE 123
R LTA V + LS+ L+ Q R L D+L E+ +L + E V+A+ K+
Sbjct: 595 RDLTARRVKETEKALSRQLQRQREHYEATIQRHLAFIDQLIEDKKVLSEKCEAVVAELKQ 654
Query: 124 ---LVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGA-----VQSGVDKTKSVVTGGVQS 175
+ +V+ AQ + + +L E + AT A + K K V G++
Sbjct: 655 EDQRCTERVAQAQ----AQHELEIKKLKELMSATEKARREKWISEKTKKIKEVTVRGLEP 710
Query: 176 VMGSRLGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSY 235
+ ++ + ++ L +AEL L + AS + RQ +
Sbjct: 711 E------------IQKLIARHKQEVRRLKSLHEAEL------LQSDERASQRCLRQAEEL 752
Query: 236 FVRLGSLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQE 295
+L E L Q E + + RA + ++ QL ++ S + + +K E QE
Sbjct: 753 REQLEREKEALGQQERERARQRQRAELEELRQ---QLEESSSALTRALRAEFEKGREEQE 809
Query: 296 KLHQMWLSWNQKQLQ 310
+ HQM L+ ++QL+
Sbjct: 810 RRHQMELNTLKQQLE 824
>gi|56550043 sarcolemma associated protein [Homo sapiens]
Length = 811
Score = 35.8 bits (81), Expect = 0.078
Identities = 58/310 (18%), Positives = 125/310 (40%), Gaps = 25/310 (8%)
Query: 98 RGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGA 157
R L E+ L++ E+ + +EL ++K +GA V+ KD LS+ + G
Sbjct: 277 RSLSNTEDECTHLKEMNERTQEELREL-ANKYNGA---VNEIKD-----LSDKLKVAEGK 327
Query: 158 VQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATS 217
+ K ++ + + L L ++ + L L S
Sbjct: 328 QEEIQQKGQAEKKELQHKIDEMEEKEQELQAKIEALQADNDFTNERLTALQEHLL----S 383
Query: 218 LDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALS 277
G D + Q + Q + G L++ + + + RA + + L + S
Sbjct: 384 KSGGDCTFIHQFIECQKKLIVEGHLTKAVEETKLSKE-NQTRAKESDFSDTLSPSKEKSS 442
Query: 278 LMETVKQGVDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQVES--RALTMFRDIAQ 335
T Q +Q L E K+ + + LQG + E ++++ + L +++A+
Sbjct: 443 DDTTDAQMDEQDLNEPLAKVSLL-----KDDLQGAQSEIEAKQEIQHLRKELIEAQELAR 497
Query: 336 QLQATCTSLGSSIQGLPTNVKDQVQQARRQVEDLQATFSSIH----SFQDLSSSILAQSR 391
+ C L + ++ ++QV+++ +Q++ LQA +H + ++ S + +R
Sbjct: 498 TSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQRLHIDTENLREEKDSEITSTR 557
Query: 392 ERVASAREAL 401
+ + SAR+ +
Sbjct: 558 DELLSARDEI 567
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.123 0.332
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,365,377
Number of Sequences: 37866
Number of extensions: 560632
Number of successful extensions: 2489
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 163
Number of HSP's that attempted gapping in prelim test: 2244
Number of HSP's gapped (non-prelim): 360
length of query: 434
length of database: 18,247,518
effective HSP length: 105
effective length of query: 329
effective length of database: 14,271,588
effective search space: 4695352452
effective search space used: 4695352452
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.