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Search of human proteins with 197927452
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
(4265 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens] 8572 0.0
gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 3158 0.0
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] 3033 0.0
gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens] 2708 0.0
gi|75677365 dynein heavy chain domain 3 [Homo sapiens] 2520 0.0
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 2093 0.0
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens] 2031 0.0
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] 2020 0.0
gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap... 2020 0.0
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 2019 0.0
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens] 2000 0.0
gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 1984 0.0
gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 1981 0.0
gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens] 1497 0.0
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] 1384 0.0
gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens] 1233 0.0
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H... 975 0.0
gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sap... 481 e-135
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] 214 1e-54
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 47 5e-04
gi|7706353 vacuolar protein sorting 24 isoform 1 [Homo sapiens] 46 7e-04
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 44 0.003
gi|112734867 retinitis pigmentosa GTPase regulator interacting p... 42 0.017
gi|210147558 hypothetical protein LOC202051 [Homo sapiens] 42 0.017
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 42 0.017
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 41 0.029
gi|71061468 centromere protein E [Homo sapiens] 40 0.065
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 39 0.11
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 39 0.11
gi|195539368 coiled-coil domain containing 149 isoform 2 [Homo s... 39 0.11
>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
Length = 4265
Score = 8572 bits (22242), Expect = 0.0
Identities = 4265/4265 (100%), Positives = 4265/4265 (100%)
Query: 1 MEQPNSKGYSLGRTPQGPECSSAPAVQVGTHRGLEYNPGKILPGSDYGLGNPPALDPKLP 60
MEQPNSKGYSLGRTPQGPECSSAPAVQVGTHRGLEYNPGKILPGSDYGLGNPPALDPKLP
Sbjct: 1 MEQPNSKGYSLGRTPQGPECSSAPAVQVGTHRGLEYNPGKILPGSDYGLGNPPALDPKLP 60
Query: 61 HLPLPPAPPTLSDLGQPRKSPLTGTDKKYPLMKQRGFYSDILSPGTLDQLGEVCRGPRMS 120
HLPLPPAPPTLSDLGQPRKSPLTGTDKKYPLMKQRGFYSDILSPGTLDQLGEVCRGPRMS
Sbjct: 61 HLPLPPAPPTLSDLGQPRKSPLTGTDKKYPLMKQRGFYSDILSPGTLDQLGEVCRGPRMS 120
Query: 121 QNLLRQADLDKFTPRVGSFEVPEDFQERMEQQCIGSTTRLLAQTDFPLQAYEPKMQVPFQ 180
QNLLRQADLDKFTPRVGSFEVPEDFQERMEQQCIGSTTRLLAQTDFPLQAYEPKMQVPFQ
Sbjct: 121 QNLLRQADLDKFTPRVGSFEVPEDFQERMEQQCIGSTTRLLAQTDFPLQAYEPKMQVPFQ 180
Query: 181 VLPGQHPRKIEIERRKQQYLSLDIEQLLFSQGIDSNKLMPRHLDHQHPQTIEQGHDPIFP 240
VLPGQHPRKIEIERRKQQYLSLDIEQLLFSQGIDSNKLMPRHLDHQHPQTIEQGHDPIFP
Sbjct: 181 VLPGQHPRKIEIERRKQQYLSLDIEQLLFSQGIDSNKLMPRHLDHQHPQTIEQGHDPIFP 240
Query: 241 IYLPLKVFDNEDFDCRTPREWINMGLEPGSLDRKPVPGKALLPTDDFLGHEDPKSQKLKY 300
IYLPLKVFDNEDFDCRTPREWINMGLEPGSLDRKPVPGKALLPTDDFLGHEDPKSQKLKY
Sbjct: 241 IYLPLKVFDNEDFDCRTPREWINMGLEPGSLDRKPVPGKALLPTDDFLGHEDPKSQKLKY 300
Query: 301 KWCEVGVLDYDEEKKLYLVHKTDEKGLVRDEMGRPILNAGVTTEGRPPLQVCQYWVPRIQ 360
KWCEVGVLDYDEEKKLYLVHKTDEKGLVRDEMGRPILNAGVTTEGRPPLQVCQYWVPRIQ
Sbjct: 301 KWCEVGVLDYDEEKKLYLVHKTDEKGLVRDEMGRPILNAGVTTEGRPPLQVCQYWVPRIQ 360
Query: 361 LLFCAEDPCMFAQRVVQANALRKNTEALLLYNLYVDCMPSDGQHVISEQSLSKIKQWALS 420
LLFCAEDPCMFAQRVVQANALRKNTEALLLYNLYVDCMPSDGQHVISEQSLSKIKQWALS
Sbjct: 361 LLFCAEDPCMFAQRVVQANALRKNTEALLLYNLYVDCMPSDGQHVISEQSLSKIKQWALS 420
Query: 421 TPRMRKGPSVLEHLSSLAREVSLDYERSMNKINFDHVVSSKPETFSYVTLPKKEEEQVPE 480
TPRMRKGPSVLEHLSSLAREVSLDYERSMNKINFDHVVSSKPETFSYVTLPKKEEEQVPE
Sbjct: 421 TPRMRKGPSVLEHLSSLAREVSLDYERSMNKINFDHVVSSKPETFSYVTLPKKEEEQVPE 480
Query: 481 RGLVSVPKYHFWEQKEDFTFVSLLTRPEVITALSKVRAECNKVTAMSLFHSSLSKYSHLE 540
RGLVSVPKYHFWEQKEDFTFVSLLTRPEVITALSKVRAECNKVTAMSLFHSSLSKYSHLE
Sbjct: 481 RGLVSVPKYHFWEQKEDFTFVSLLTRPEVITALSKVRAECNKVTAMSLFHSSLSKYSHLE 540
Query: 541 EFEQIQSQTFSQVQMFLKDSWISSLKVAMRSSLRDMSKGWYNLYETNWEVYLMSKLRKLM 600
EFEQIQSQTFSQVQMFLKDSWISSLKVAMRSSLRDMSKGWYNLYETNWEVYLMSKLRKLM
Sbjct: 541 EFEQIQSQTFSQVQMFLKDSWISSLKVAMRSSLRDMSKGWYNLYETNWEVYLMSKLRKLM 600
Query: 601 ELVKYMLQDTLRFLVQDSLASFSQFISDTCCSVLNCTDDMVWGDDLINSPYRPRKNPLFI 660
ELVKYMLQDTLRFLVQDSLASFSQFISDTCCSVLNCTDDMVWGDDLINSPYRPRKNPLFI
Sbjct: 601 ELVKYMLQDTLRFLVQDSLASFSQFISDTCCSVLNCTDDMVWGDDLINSPYRPRKNPLFI 660
Query: 661 MDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATHAVPQLEKLVMEDIFISGDPLLESVG 720
MDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATHAVPQLEKLVMEDIFISGDPLLESVG
Sbjct: 661 MDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATHAVPQLEKLVMEDIFISGDPLLESVG 720
Query: 721 LHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLAQEVR 780
LHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLAQEVR
Sbjct: 721 LHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLAQEVR 780
Query: 781 EVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKKRKALATSVLDILAKNLHKEV 840
EVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKKRKALATSVLDILAKNLHKEV
Sbjct: 781 EVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKKRKALATSVLDILAKNLHKEV 840
Query: 841 DSICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLY 900
DSICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLY
Sbjct: 841 DSICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLY 900
Query: 901 NLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVV 960
NLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVV
Sbjct: 901 NLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVV 960
Query: 961 AGFSIHVEISRAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVKEF 1020
AGFSIHVEISRAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVKEF
Sbjct: 961 AGFSIHVEISRAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVKEF 1020
Query: 1021 QPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEV 1080
QPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEV
Sbjct: 1021 QPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEV 1080
Query: 1081 ALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQD 1140
ALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQD
Sbjct: 1081 ALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQD 1140
Query: 1141 HIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDH 1200
HIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDH
Sbjct: 1141 HIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDH 1200
Query: 1201 IVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQL 1260
IVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQL
Sbjct: 1201 IVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQL 1260
Query: 1261 PVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDSLRDCNKILDLVQKGLSEYLET 1320
PVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDSLRDCNKILDLVQKGLSEYLET
Sbjct: 1261 PVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDSLRDCNKILDLVQKGLSEYLET 1320
Query: 1321 KRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQEDLEITHMYSAEGE 1380
KRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQEDLEITHMYSAEGE
Sbjct: 1321 KRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQEDLEITHMYSAEGE 1380
Query: 1381 EVQLCFSIYPSSNVEDWLREVERSMKASVHDIIEKAIRAYPTMPRTQWVLNWPGQVTIAG 1440
EVQLCFSIYPSSNVEDWLREVERSMKASVHDIIEKAIRAYPTMPRTQWVLNWPGQVTIAG
Sbjct: 1381 EVQLCFSIYPSSNVEDWLREVERSMKASVHDIIEKAIRAYPTMPRTQWVLNWPGQVTIAG 1440
Query: 1441 CQTYWTMEVAEALEAGNLRSQLFPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIEVHAK 1500
CQTYWTMEVAEALEAGNLRSQLFPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIEVHAK
Sbjct: 1441 CQTYWTMEVAEALEAGNLRSQLFPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIEVHAK 1500
Query: 1501 DVVSKLIQENVVSVNDFQWISQLRYYWTNNDLYIRAVNAEFIYGYEYLGNSGRLVITPLT 1560
DVVSKLIQENVVSVNDFQWISQLRYYWTNNDLYIRAVNAEFIYGYEYLGNSGRLVITPLT
Sbjct: 1501 DVVSKLIQENVVSVNDFQWISQLRYYWTNNDLYIRAVNAEFIYGYEYLGNSGRLVITPLT 1560
Query: 1561 DRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFF 1620
DRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFF
Sbjct: 1561 DRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFF 1620
Query: 1621 KGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLVPSCAVF 1680
KGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLVPSCAVF
Sbjct: 1621 KGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLVPSCAVF 1680
Query: 1681 ITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITTTFKL 1740
ITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITTTFKL
Sbjct: 1681 ITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITTTFKL 1740
Query: 1741 SSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQEDLKL 1800
SSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQEDLKL
Sbjct: 1741 SSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQEDLKL 1800
Query: 1801 FSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLML 1860
FSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLML
Sbjct: 1801 FSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLML 1860
Query: 1861 VGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTH 1920
VGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTH
Sbjct: 1861 VGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTH 1920
Query: 1921 EWTDGIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLT 1980
EWTDGIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLT
Sbjct: 1921 EWTDGIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLT 1980
Query: 1981 EAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIECWLRKLPPLLKPYEEHFKAL 2040
EAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIECWLRKLPPLLKPYEEHFKAL
Sbjct: 1981 EAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIECWLRKLPPLLKPYEEHFKAL 2040
Query: 2041 FVSFLEESISFVRSSVKEVIASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIV 2100
FVSFLEESISFVRSSVKEVIASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIV
Sbjct: 2041 FVSFLEESISFVRSSVKEVIASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIV 2100
Query: 2101 ELIEPWFIFSLIWSVGATGDSSGRTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGI 2160
ELIEPWFIFSLIWSVGATGDSSGRTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGI
Sbjct: 2101 ELIEPWFIFSLIWSVGATGDSSGRTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGI 2160
Query: 2161 SGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNK 2220
SGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNK
Sbjct: 2161 SGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNK 2220
Query: 2221 KPVLCIGPTGTGKTLTISDKLLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKRRKGV 2280
KPVLCIGPTGTGKTLTISDKLLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKRRKGV
Sbjct: 2221 KPVLCIGPTGTGKTLTISDKLLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKRRKGV 2280
Query: 2281 FGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFV 2340
FGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFV
Sbjct: 2281 FGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFV 2340
Query: 2341 CAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVP 2400
CAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVP
Sbjct: 2341 CAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVP 2400
Query: 2401 GAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVED 2460
GAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVED
Sbjct: 2401 GAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVED 2460
Query: 2461 QVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCMEQWEVTFNKVCPFQPILYGDFMS 2520
QVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCMEQWEVTFNKVCPFQPILYGDFMS
Sbjct: 2461 QVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCMEQWEVTFNKVCPFQPILYGDFMS 2520
Query: 2521 PGSDVKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALG 2580
PGSDVKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALG
Sbjct: 2521 PGSDVKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALG 2580
Query: 2581 NALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPIT 2640
NALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPIT
Sbjct: 2581 NALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPIT 2640
Query: 2641 FLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMA 2700
FLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMA
Sbjct: 2641 FLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMA 2700
Query: 2701 AYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNE 2760
AYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNE
Sbjct: 2701 AYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNE 2760
Query: 2761 IPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQ 2820
IPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQ
Sbjct: 2761 IPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQ 2820
Query: 2821 KKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAI 2880
KKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAI
Sbjct: 2821 KKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAI 2880
Query: 2881 AEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRA 2940
AEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRA
Sbjct: 2881 AEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRA 2940
Query: 2941 MQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFD 3000
MQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFD
Sbjct: 2941 MQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFD 3000
Query: 3001 KDNIGDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQAL 3060
KDNIGDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQAL
Sbjct: 3001 KDNIGDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQAL 3060
Query: 3061 LEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAG 3120
LEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAG
Sbjct: 3061 LEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAG 3120
Query: 3121 KLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQL 3180
KLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQL
Sbjct: 3121 KLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQL 3180
Query: 3181 RSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQA 3240
RSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQA
Sbjct: 3181 RSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQA 3240
Query: 3241 NKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYK 3300
NKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYK
Sbjct: 3241 NKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYK 3300
Query: 3301 QQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQ 3360
QQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQ
Sbjct: 3301 QQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQ 3360
Query: 3361 VVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKM 3420
VVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKM
Sbjct: 3361 VVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKM 3420
Query: 3421 KAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNI 3480
KAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNI
Sbjct: 3421 KAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNI 3480
Query: 3481 FLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKI 3540
FLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKI
Sbjct: 3481 FLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKI 3540
Query: 3541 NQSEWRYLLSGGSISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVI 3600
NQSEWRYLLSGGSISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVI
Sbjct: 3541 NQSEWRYLLSGGSISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVI 3600
Query: 3601 FDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANL 3660
FDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANL
Sbjct: 3601 FDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANL 3660
Query: 3661 SVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSS 3720
SVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSS
Sbjct: 3661 SVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSS 3720
Query: 3721 IERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSK 3780
IERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSK
Sbjct: 3721 IERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSK 3780
Query: 3781 MTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFN 3840
MTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFN
Sbjct: 3781 MTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFN 3840
Query: 3841 IPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILED 3900
IPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILED
Sbjct: 3841 IPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILED 3900
Query: 3901 FYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQN 3960
FYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQN
Sbjct: 3901 FYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQN 3960
Query: 3961 ETFALLGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEESM 4020
ETFALLGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEESM
Sbjct: 3961 ETFALLGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEESM 4020
Query: 4021 NTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAY 4080
NTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAY
Sbjct: 4021 NTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAY 4080
Query: 4081 PSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFARKFVISID 4140
PSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFARKFVISID
Sbjct: 4081 PSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFARKFVISID 4140
Query: 4141 TISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWL 4200
TISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWL
Sbjct: 4141 TISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWL 4200
Query: 4201 LPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALI 4260
LPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALI
Sbjct: 4201 LPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALI 4260
Query: 4261 CALDY 4265
CALDY
Sbjct: 4261 CALDY 4265
>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
Length = 4024
Score = 3158 bits (8187), Expect = 0.0
Identities = 1680/3685 (45%), Positives = 2353/3685 (63%), Gaps = 111/3685 (3%)
Query: 645 DLINSP---YRPRKNPLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATHAVPQLE 701
DLI P R ++P FIM L+LD+ + + L + LN++D I A VP++E
Sbjct: 385 DLIAQPPDSVRAFEHPGFIMRLILDNDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVE 444
Query: 702 -KLVMEDIFISGDPLLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNN 760
KL + S L+ + L+E +V+ + I + K + + + Y KY L
Sbjct: 445 TKLYSKWESKSKPTTLKPIILNE-IVDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITR 503
Query: 761 DIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKK 820
+ + + +++ + + + + E + + +I +G F ++ + + ++L K+
Sbjct: 504 KAERDVDNFLAENHSYEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIRALVKR 563
Query: 821 RKALATSVLDILAKNLHKEVDS-ICEEFRSISRKIYEKPNSIEELAELREWMKGIPER-L 878
+ +L + ++ H+EV++ +C+EF I+ K P + EL E++ +++ + +
Sbjct: 564 ADIICGKLLAKMFRD-HQEVNTRLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEVTDM 622
Query: 879 VGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDE-EK 937
+ LE+R+V + + E++ N S D W + +G+I ++ ++++ E+
Sbjct: 623 IELEQRLVDSKNCLAFLIEYV-NFSPADMRLNNSVFQWYGR-MGEIFEEHRKIIKEKIEQ 680
Query: 938 FRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQLAMLYN 997
+++ + F E+LE F ++ + + + +L +N
Sbjct: 681 YQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQFN 740
Query: 998 NRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNV 1057
E F + Y + ++ PYL L+ TA ++ +W P ++ +Q+E ++
Sbjct: 741 AEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVEADI 800
Query: 1058 VEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQ 1117
++ ++K K F D P + +R+++E+FK +IPLIQ + NPG+R RHWE +S
Sbjct: 801 GNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAI 860
Query: 1118 ININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVL 1177
+ ++P + T + L+MNL+ +I+ ++E A KEY++E+A++KM EW + F +
Sbjct: 861 VGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIH 920
Query: 1178 PYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEW 1237
Y+ T T+IL S DE LLDDHI+ TQ M SP+ KP+E+++ WE KL L QE+L+EW
Sbjct: 921 SYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEW 980
Query: 1238 LNCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRML 1297
L Q +WLYLEPIFSS DI Q+P E +R+ +++ W+ IM++ +++ V+ V + RML
Sbjct: 981 LKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRML 1040
Query: 1298 DSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCF 1357
+ L+ N++L+L+ KGL+EYLE KR FPRF+FLS+DELLEILS+TKDPT VQPHL+KCF
Sbjct: 1041 ERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCF 1100
Query: 1358 ENIARLLFQEDLEITHMYSAEGEEVQLCFSIYPSS---NVEDWLREVERSMKASVHDIIE 1414
E IA++ F E L+ITHM S+EGE V+L I + VE WL E+ER M S+H +
Sbjct: 1101 EGIAKVEFTETLDITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTG 1160
Query: 1415 KAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLRSQLFPQLC-QQLSDL 1473
A AY R WV +WPGQ + Q +WT EV A+ G + + + C +Q+ D+
Sbjct: 1161 DATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIKALEQYLKTCNRQIDDI 1220
Query: 1474 VALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNNDLY 1533
V LVRGKLS R L AL+V++VHA+DV+S L+++N+ +DF+W+SQLRYYW N L
Sbjct: 1221 VTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENHLE 1280
Query: 1534 IRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKD 1593
+ +NA YGYEYLGNS RLVITPLTDRCY TL GALHL GGAP GPAGTGKTETTKD
Sbjct: 1281 TKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKD 1340
Query: 1594 LGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTI 1653
L KA+A Q VVFNCSD LD++A+GKFFKGL S GAWACFDEFNRID+EVLSVVAQQI TI
Sbjct: 1341 LAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTI 1400
Query: 1654 QKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAM 1713
Q+ + MFEG E+ L P+CAVFITMNPGYAGR+ELPDNLKALFR VAMMVPDYAM
Sbjct: 1401 QRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAM 1460
Query: 1714 ITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENP 1773
I EI LYS GF A L+ KI T++L SEQLSSQ HYD+GMRAVK+V++AAGNLK + P
Sbjct: 1461 IAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYP 1520
Query: 1774 SMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNS 1833
+ NEE++ LR+I DVN+PKFL DL LF GI SDLFP +K DY L AI++ C +
Sbjct: 1521 NENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASM 1580
Query: 1834 NLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMY 1893
NL+ F K +Q+YE +VRHG M+VG GK++ YRVLA A+ + G+
Sbjct: 1581 NLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDI-----CEKGLM 1635
Query: 1894 EA--VNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPV 1951
E V VLNPKS+TMGQLYG+FD ++HEW+DG+ + RA A + ++KW +FDGPV
Sbjct: 1636 EENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPV 1695
Query: 1952 DAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPS 2011
DA+WIENMNTVLDDNKKLCL SGEII+++ M ++FE DL VASPATVSRCGM+Y+EP
Sbjct: 1696 DAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPH 1755
Query: 2012 ILGLMPFIECWLRKLPPLLKPYEEHF-KALFVSFLEESISFVRSSVKEVIASTNCNLTMS 2070
+LG P + W+ LP + ++ F LF + S+ F+R KE+ +++ NL S
Sbjct: 1756 MLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRS 1815
Query: 2071 LLKLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSGRTSFSHW 2130
L+ L+DCF F LK+ + ++E I F+FSLIWSVGA+ R F+
Sbjct: 1816 LMNLIDCFMDDFADEVKLKERNDRETYSLLEGI---FLFSLIWSVGASCTDDDRLKFNKI 1872
Query: 2131 LRLKMEN---------------------EQLTLLFPEEGLVFDYRLEDAGISGTNDSEDE 2169
LR ME+ + LT+ FPE+G ++DY+ GI
Sbjct: 1873 LRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIG-------- 1924
Query: 2170 EEEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPT 2229
K W+K + + P D + IIVPT+DT++ S L+++L T++KP + +GPT
Sbjct: 1925 ----KWEPWIKKLKEAPPIPK--DVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPT 1978
Query: 2230 GTGKTLTISDKLLKNLALD-YISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRN 2288
GTGK++ I++ LL L + Y + FSA+T+A QTQ+ + SKLDKRRKGVFGPPLG+
Sbjct: 1979 GTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKR 2038
Query: 2289 FIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGG 2348
+ F+DD+NMPA E YGAQPPIELLRQW+DH WYD K K LVDI +CAMGPPGG
Sbjct: 2039 MVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIK-LVDIQIMCAMGPPGG 2097
Query: 2349 GRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHF 2408
GRN VTPR MRHFN ++ E + S IFS IL L E Y+
Sbjct: 2098 GRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHL-----EICYKF----PDEFLDL 2148
Query: 2409 TEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLW 2468
T +V T+ +Y LLPTPAKSHY FNLRD S+V QG+ ++ P E + RLW
Sbjct: 2149 TTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLW 2208
Query: 2469 YHENCRVFRDRLVNEEDRSWF----DQLLKRCM-EQWEVTFNKVC----------PFQPI 2513
HE RV+ DRL++ DRSW ++L+ M E + F ++ + +
Sbjct: 2209 VHEVLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSL 2268
Query: 2514 LYGDFMSPGSDVKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISR 2573
++ DF P + +Y I + ++E ++E+YN I+ + LVLF A+ HI RISR
Sbjct: 2269 MFCDFHDPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISR 2328
Query: 2574 TLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAG 2633
L+Q +ALL+GVGGSGR S+TRLA+HMA+Y FQ+E+SK Y +EW +D+K +L K
Sbjct: 2329 ILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCA 2388
Query: 2634 LQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQG--- 2690
+ FLF+DTQIK ESFLED++N+LN+G+IPNL+ DE+ +I MR +++
Sbjct: 2389 EGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTK 2448
Query: 2691 -LQPTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEA 2749
+ L + RS +H+VL MSPIG+ FR RLR+FP+LVNCCTIDWF WP +A
Sbjct: 2449 QTDGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDA 2508
Query: 2750 LKSVATVFLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLE 2809
L++VA+ FL EI E S+E G I +C H S + EL R+NYVTP SYLE
Sbjct: 2509 LQAVASRFLEEI---EMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLE 2565
Query: 2810 LLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTML 2869
L+ F +L+ +K+ E+ K R + GL+KL S VA MQ +LE++HP L+ A+K+
Sbjct: 2566 LISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDE 2625
Query: 2870 TMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRN 2929
M I+ ++ +T V+ +E ANE+A ++AI D+ DL ALP L++ALA+L
Sbjct: 2626 MMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDT 2685
Query: 2930 LNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEK-PGTKVDDYWEPGKGLLQD 2988
L D+T V++M+ PP GVKLV+EA+CI+KGIK K+P G K++D+W P K LL D
Sbjct: 2686 LTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGD 2745
Query: 2989 PGHFLESLFKFDKDNIGDVVIKAIQP-YIDNEEFQPATIAKVSKACTSICQWVRAMHKYH 3047
FL+SL ++DKDNI + I+ YI N +F P I S A +C+WV AM Y
Sbjct: 2746 M-RFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYD 2804
Query: 3048 FVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELEL 3107
VAK V PK+ L A+ +L + L + + L+EV+D +A +Q KK +LE
Sbjct: 2805 KVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLEN 2864
Query: 3108 KCEQCEQRLGRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQ 3167
+ + C ++L RA +LI GL EK RW T L + N++GD+L+++G VAYLG FT
Sbjct: 2865 QVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTST 2924
Query: 3168 YRTVLYDSWVKQLRSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFS 3227
YR W + ++P + + +L+GTLG V IR+W IAGLP+D+ S++NG+I +
Sbjct: 2925 YRQNQTKEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNA 2984
Query: 3228 QRWTHFIDPQSQANKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELD 3287
+RW IDPQSQANKWIKNMEK N L V KLS+ D++R++EN I+FG P LLENVGEELD
Sbjct: 2985 RRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELD 3044
Query: 3288 PALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFT 3347
P LEP+LLKQT+KQ G+T ++LGD+ I Y DFR YITTKL NPHY PE S K+TL+NF
Sbjct: 3045 PILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFM 3104
Query: 3348 LSPSGLEDQLLGQVVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVD 3407
++P G++DQLLG VVA+ERPDLEE K LI+ A+ +++LK+IED+IL LSSSEGN ++
Sbjct: 3105 ITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILE 3164
Query: 3408 DMELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVD 3467
D IK+L +SK A EI K +AE+TEK ID TRM Y P+AI + ILFF ++DLAN++
Sbjct: 3165 DETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIE 3224
Query: 3468 PMYQYSLEWFLNIFLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAF 3527
PMYQYSL WF+N+F+ I NSE+++ L KR+ + + TYSLY NVCRSLFEK KL+F+F
Sbjct: 3225 PMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSF 3284
Query: 3528 LLCVRIMMNEGKINQSEWRYLLSGGSISIMTENPAPD---WLSDRAWRDILALSNLPTFS 3584
L + ++++E IN++EWR+LL+GG I +NP + WL ++W +I L +LP F
Sbjct: 3285 CLTINLLLHERAINKAEWRFLLTGG---IGLDNPYANLCTWLPQKSWDEICRLDDLPAFK 3341
Query: 3585 SFSSDFVKHLSEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFV 3644
+ +F++ ++ ++DSLEPH E P W+ ++FQ++L++RCLR DKV +Q+F+
Sbjct: 3342 TIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFI 3401
Query: 3645 ATNLEPRFIEPQTANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKF-SKKLSAI 3703
L FIEP +L+ F DSN PLIFVLSPG DP A L KFA++ + KLS++
Sbjct: 3402 INRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSL 3461
Query: 3704 SLGQGQGPRAEAMMRSSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLT 3763
SLGQGQGP A M+ +++ G WV QNCHLA SWMP LE++ E ++P+ H DFR+WLT
Sbjct: 3462 SLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLT 3521
Query: 3764 SLPSNKFPVSILQNGSKMTIEPPRGVRANLLKSY---SSLGEDFLNSCHKVMEFKSLLLS 3820
S PS FPVS+LQNG KMT E P+G+RAN+++SY +F SC K EFK LL
Sbjct: 3522 SYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKKLLYG 3581
Query: 3821 LCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEIN 3880
LC FH ERRKFGPLG+NIPYEF + DLRI + QL MFL++Y+++PY+ L+Y GE N
Sbjct: 3582 LCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMTGECN 3641
Query: 3881 YGGRVTDDWDRRCIMNILEDFYNPDVL-SPEHSYSASGIYHQIPPTYDLHGYLSYIKSLP 3939
YGGRVTDDWDRR + +IL F+NP+++ + ++ + +SGIY +PP+ D Y+ Y K+LP
Sbjct: 3642 YGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYF-VPPSGDHKSYIEYTKTLP 3700
Query: 3940 LNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKV 3999
L PEIFG++ NA+IT Q+ET L I+ Q +S+ AG++ +E+V +V +IL K+
Sbjct: 3701 LTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSAGAGAKSSDEVVNEVASDILGKL 3760
Query: 4000 PEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQL 4059
P +++ M +YP Y +SMNTVLVQE+ R+N+LL+ I + ++ KA+KGL VMS+ L
Sbjct: 3761 PNNFDIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDL 3820
Query: 4060 ELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFF 4119
E + +S+ N +PE+W K+YPSLKPL S+V D L RL FLQ W + G P VFW+SGFFF
Sbjct: 3821 EEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFF 3880
Query: 4120 PQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPE 4179
QAFLTG QN+ARK+ I ID + FD++VM + E P+ G +IHGLFL+GA W+ +
Sbjct: 3881 TQAFLTGAQQNYARKYTIPIDLLGFDYEVMED--KEYKHPPEDGVFIHGLFLDGASWNRK 3938
Query: 4180 AFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVI 4239
+LAES PK LY + V+WL P + Y+ P+YKT R G LSTTGHSTN+VI
Sbjct: 3939 IKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVI 3998
Query: 4240 AVEIPTHQPQRHWIKRGVALICALD 4264
A+ +P+ QP+ HWI RGVAL+C L+
Sbjct: 3999 AMTLPSDQPKEHWIGRGVALLCQLN 4023
>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
Length = 4116
Score = 3033 bits (7863), Expect = 0.0
Identities = 1620/3612 (44%), Positives = 2286/3612 (63%), Gaps = 132/3612 (3%)
Query: 715 LLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNN----DIASFLKTYQ 770
LL +V E LV + K + Y Y+KY++L +N +IA+FLK
Sbjct: 574 LLGTVNAEEKLVSDFLIQTFKVFQKNQVGPCKYLNVYKKYVDLLDNTAEQNIAAFLKENH 633
Query: 771 TQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKKRKALATSVLD 830
+ V ++ R EI +S+ ++ + F ++ + L ++ + L ++
Sbjct: 634 D---IDDFVTKINAIKKRRNEI--ASMNITVPLAMFCLDATALNHDLCERAQNLKDHLIQ 688
Query: 831 ILAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMKG--------IPERLVGLE 882
SIC ++ I+ K+ E P + +EL L E++K + +L
Sbjct: 689 FQVDVNRDTNTSICNQYSHIADKVSEVPANTKELVSLIEFLKKSSAVTVFKLRRQLRDAS 748
Query: 883 ERIVKVMD----DYQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKF 938
ER+ +MD YQ+ D F N + + + A K + EL + + + E F
Sbjct: 749 ERLEFLMDYADLPYQIEDIF-DNSRNLLLHKRDQAEMDLIKRCSEFELRLEGYHRELESF 807
Query: 939 RKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQLAMLYNN 998
RK ++M + +E L +E++ + R + + L N
Sbjct: 808 RKREVMTTEEMKHNVEKL----------------NELSKNLNRAFAEFE-------LINK 844
Query: 999 RERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVV 1058
E + + Y L M+K PY LW+TA ++ SE WMN PL ++AEQ+ + +
Sbjct: 845 EEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQIAEEIG 904
Query: 1059 EAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQI 1118
++T +K +K D+PA + +A +++ +I++FK YIP++ NPGM+ RHW+ +S +
Sbjct: 905 NMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQISEIV 964
Query: 1119 NINVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLP 1178
++P + LE +E + + A KEY++E+ LD+M+ +W + F+ +
Sbjct: 965 GYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTFSFVK 1024
Query: 1179 YKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWL 1238
Y+ TDT IL + D+ LLDDH++ TQ M SP+ KP E WE KL Q+ L+ WL
Sbjct: 1025 YRDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNLDAWL 1084
Query: 1239 NCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLD 1298
CQ +WLYLEPIFSSEDI Q+P E +++ ++ WK +M A ++ ++ RM +
Sbjct: 1085 KCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAADQPRMAE 1144
Query: 1299 SLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFE 1358
L++ N +L+ +QKGL++YLE KR FPRF+FLS+DELLEILS+TKDP VQPHL+KCFE
Sbjct: 1145 KLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLKKCFE 1204
Query: 1359 NIARLLFQEDLEITHMYSAEGEEVQLCFSIYPSSN---VEDWLREVERSMKASVHDIIEK 1415
IA+L F ++LEI M S+E E V IYP++ VE WL++VE+ M AS+ ++I
Sbjct: 1205 GIAKLEFTDNLEIVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMMLASMREVIGL 1264
Query: 1416 AIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLRSQLFPQLCQQLSDLVA 1475
I AY +PR WVL WPGQV I +WT EV++AL A N + Q++ +V
Sbjct: 1265 GIEAYVKVPRNHWVLQWPGQVVICVSSIFWTQEVSQAL-AENTLLDFLKKSNDQIAQIVQ 1323
Query: 1476 LVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNNDLYIR 1535
LVRGKLS R L AL VI+VHA+DVV+KL ++ V +NDFQWISQLRYYW D+ ++
Sbjct: 1324 LVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQWISQLRYYWVAKDVQVQ 1383
Query: 1536 AVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLG 1595
+ E +YGYEYLGNS RLVITPLTDRCY TL GAL L GGAP GPAGTGKTETTKDL
Sbjct: 1384 IITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLA 1443
Query: 1596 KALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQK 1655
KALA Q VVFNCSD LD+ AMGKFFKGLA AGAWACFDEFNRI++EVLSVVAQQI +IQ+
Sbjct: 1444 KALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQ 1503
Query: 1656 AQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMIT 1715
A ++++ F+FEG E+ L P+CAVFITMNPGYAGR ELPDNLKALFR VAMMVPDYA+I
Sbjct: 1504 AIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYALIG 1563
Query: 1716 EISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSM 1775
EISLYS GF ++ LA+KI T++L SEQLSSQ HYD+GMRAVK+V++AAGNLK + P
Sbjct: 1564 EISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEE 1623
Query: 1776 NEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNL 1835
NE ++ LRA+ DVN+ KFL +D+ LF GI+SDLFP + DY + + + + + L
Sbjct: 1624 NESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKL 1683
Query: 1836 KDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYE- 1894
+ V F+ K IQ+YE +VRHG M+VG GK++ Y+VLAAA+ L + M E
Sbjct: 1684 QPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDLHA----ANQMEEF 1739
Query: 1895 AVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPVDAI 1954
AV Y ++NPK+ITMGQLYG FD ++HEW DG+ ++ R A + ++KW +FDGPVDAI
Sbjct: 1740 AVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSLSDDRKWIIFDGPVDAI 1799
Query: 1955 WIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILG 2014
WIENMNTVLDDNKKLCL SGEII++ M+++FE DL ASPATVSRCGM+Y+EP LG
Sbjct: 1800 WIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQLG 1859
Query: 2015 LMPFIECWLRKLPP-LLKPYEEHFKALFVSFLEESISFVRSSVKEVIASTNCNLTMSLLK 2073
P + ++ LP L K ++E +F+ ++ + F R K V+ ++ +L S+++
Sbjct: 1860 WKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQTSPIHLAFSMMR 1919
Query: 2074 LLDCFFKPFLPREGLKKIPSEKLS--RIVELIEPWFIFSLIWSVGATGDSSGRTSFSHWL 2131
L E + E LS +I ++ F+FSL+W+V T ++ R F +
Sbjct: 1920 LYSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTINADSRKKFDVFF 1979
Query: 2132 RL----------KMENEQLTL--LFPEEGLVFDYRL--EDAGISGTNDSEDEEEEYKQVA 2177
R + ++ +LT +FPE G ++D+ + +G T +EE K A
Sbjct: 1980 RNLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIKQASGHWETWTQYITKEEEKVPA 2039
Query: 2178 WVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTI 2237
K + +I+PTM+T + S L L ++ P+L +GPTGTGK+
Sbjct: 2040 GAKVSE---------------LIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAIT 2084
Query: 2238 SDKLLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLN 2297
++ LL Y+ + + FSARTSANQTQD I SKLD+RRKG+FGPP+G+ + F+DDLN
Sbjct: 2085 NNFLLHLPKNTYLPNCINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLN 2144
Query: 2298 MPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRL 2357
MPA E YGAQPPIELLRQW+DHG W+D+K ++VD+ V AMGPPGGGRN +T R
Sbjct: 2145 MPAKEVYGAQPPIELLRQWIDHGYWFDKKDTTRL-DIVDMLLVTAMGPPGGGRNDITGRF 2203
Query: 2358 MRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATI 2417
RH N +S ++ +IFS+I+ +W G + + + + LV+AT
Sbjct: 2204 TRHLNIISINAFEDDILTKIFSSIV-DWHFGKGFDVMF----------LRYGKMLVQATK 2252
Query: 2418 MVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFR 2477
+Y LPTP+KSHY FNLRD S+V QG+L+ ++D + +RLW HE RVF
Sbjct: 2253 TIYRDAVENFLPTPSKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFY 2312
Query: 2478 DRLVNEEDRSWFDQLLKRCMEQ-WEVTFNKVC------------PFQPILYGDFMSPGSD 2524
DRL+++EDR F ++K ++ T KV + + +GD+ P SD
Sbjct: 2313 DRLIDKEDRQVFFNMVKETTSNCFKQTIEKVLIHLSPTGKIVDDNIRSLFFGDYFKPESD 2372
Query: 2525 VKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALGNALL 2584
K Y+ IT ++ V+E Y+E++N I+ A + LV+F A+ HI RI R L+Q G+ LL
Sbjct: 2373 QKIYDEITDLKQLTVVMEHYLEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLL 2432
Query: 2585 LGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFS 2644
+G+GGSGR S +L++ M YE +QIE++KNY ++WR+D+KK++L+ G+ FLF+
Sbjct: 2433 VGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVFLFA 2492
Query: 2645 DTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQG--LQPTKANLMAAY 2702
D QIK+ESF+EDIN +LN+GD+PN++ ADE+ IV M+ + QG ++ T ++ +
Sbjct: 2493 DNQIKDESFVEDINMLLNTGDVPNIFPADEKADIVEKMQTAARTQGEKVEVTPLSMYNFF 2552
Query: 2703 TGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIP 2762
RV + I L MSPIG+ FR RLR FPSL+NCCTIDWF WP +AL+ VA FL ++
Sbjct: 2553 IERVINKISFSLAMSPIGDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVE 2612
Query: 2763 ELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKK 2822
++ + E+ + +C Y +SV K ++Y +L RHNYVTP SYLEL+ F L+ K+
Sbjct: 2613 LDDNIRVEV---VSMCKYFQESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKR 2669
Query: 2823 LELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAE 2882
E+ +NR +GL KL + VA MQ +L ++ P L +++T M +I+ +T A+
Sbjct: 2670 QEVAMMRNRYLTGLQKLDFAASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETREAD 2729
Query: 2883 ETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQ 2942
+ VQ +E +AN A AQ I ++ + DL EA+PAL+AALA+L LN D++ V++MQ
Sbjct: 2730 GKKLLVQADEKEANVAAAIAQGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKSMQ 2789
Query: 2943 RPPPGVKLVIEAVCIMKGIKPKKVPGEK-PGTKVDDYWEPGKGLLQDPGHFLESLFKFDK 3001
PP VKLV+E++CIMKG+KP++ P G ++DYW K +L D FLESL +DK
Sbjct: 2790 NPPGPVKLVMESICIMKGMKPERKPDPSGSGKMIEDYWGVSKKILGDL-KFLESLKTYDK 2848
Query: 3002 DNIGDVVIKAIQP-YIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQAL 3060
DNI + +K I+ +I++ EFQPA I VS AC +C+WVRAM Y VAK V PKR+ L
Sbjct: 2849 DNIPPLTMKRIRERFINHPEFQPAVIKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRERL 2908
Query: 3061 LEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAG 3120
EA+ L + L++ + L+ V D + + + E TKK++LE E C Q+L RA
Sbjct: 2909 REAEGKLAAQMQKLNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAE 2968
Query: 3121 KLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQL 3180
KLI+GL EK RW E L N++GDVL+++G VAYLG FT YR + W+ +
Sbjct: 2969 KLISGLGGEKDRWTEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQWLAEC 3028
Query: 3181 RSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQA 3240
+ +P S+ +L TLG+P+KIR+WQIAGLP D+ S++NG+I S+RW IDP QA
Sbjct: 3029 KDKVIPGFSDFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSRRWALMIDPHGQA 3088
Query: 3241 NKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYK 3300
NKWIKNMEK N L V K SD +++R +ENA++ G P L+EN+GEELD ++EP+LLK T+K
Sbjct: 3089 NKWIKNMEKANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKATFK 3148
Query: 3301 QQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQ 3360
QQG ++LG+ +I Y DF++YITT+L NPHY PE++ K+ L+NF ++P GL+DQLLG
Sbjct: 3149 QQGVEYMRLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGI 3208
Query: 3361 VVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKM 3420
V A+E+P+LEE KNQLI+ +AK ++ LK+IED+IL LS S+GN ++D IKVL +SK+
Sbjct: 3209 VAAKEKPELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKV 3268
Query: 3421 KAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNI 3480
+ EI K ++A TE ID TRM Y PVA+ + +FFC+SDLAN++PMYQYSL WF+N+
Sbjct: 3269 LSEEISEKQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINL 3328
Query: 3481 FLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKI 3540
++ + +S +++ L RI I + T S+Y+NVCRSLFEK KL+F+ LL + IM + +I
Sbjct: 3329 YMHSLTHSTKSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEI 3388
Query: 3541 NQSEWRYLLSGG-SISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRV 3599
+ W +LL+GG ++ NPAP WLS++AW +I+ S LP ++L E+++
Sbjct: 3389 TEEVWYFLLTGGIALDNPYPNPAPQWLSEKAWAEIVRASALPKLHGLMEHLEQNLGEWKL 3448
Query: 3600 IFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTAN 3659
I+DS PH E LPG W ++ +K+++LRCLR DK+ A+++F+A ++ +IE T +
Sbjct: 3449 IYDSAWPHEEQLPGSW-KFSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFD 3507
Query: 3660 LSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKF-SKKLSAISLGQGQGPRAEAMMR 3718
L + DS+ PLIFVLSP DP A L KFA+++ + ISLGQGQGP A M+
Sbjct: 3508 LQGSYNDSSCCAPLIFVLSPSADPMAGLLKFADDLGMGGTRTQTISLGQGQGPIAAKMIN 3567
Query: 3719 SSIERGKWVFFQNCHLAPSWMPALERLIEH-INPDKVHRDFRLWLTSLPSNKFPVSILQN 3777
++I+ G WV QNCHLA SWMP LE++ E I P+ + FRLWLTS PS KFPVSILQN
Sbjct: 3568 NAIKDGTWVVLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEKFPVSILQN 3627
Query: 3778 GSKMTIEPPRGVRANLLKSYSS---LGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKF 3834
G KMT EPP+G+RANLL+SY + F SC K + ++ +L LC FH ERR F
Sbjct: 3628 GIKMTNEPPKGLRANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQERRNF 3687
Query: 3835 GPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCI 3894
GPLG+NIPYEF + DLRI + Q++MFL++Y ++P+ L Y GE NYGGRVTDD DRR +
Sbjct: 3688 GPLGWNIPYEFNESDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDKDRRLL 3747
Query: 3895 MNILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNAN 3954
+++L FY ++ +S + Y+ IPP Y+ Y+++LP+ PE+FGLH+NA+
Sbjct: 3748 LSLLSMFYCKEIEEDYYSLAPGDTYY-IPPHGSYQSYIDYLRNLPITAHPEVFGLHENAD 3806
Query: 3955 ITFAQNETFALLGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKYPV 4014
IT ET L ++ P+ S + +E+VE++ Q+IL K+P +L+ VM YPV
Sbjct: 3807 ITKDNQETNQLFEGVLLTLPRQSGGSGKSPQEVVEELAQDILSKLPRDFDLEEVMKLYPV 3866
Query: 4015 LYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPEL 4074
+YEESMNTVL QE+IR+NRL +V+ ++L +L +A+KG V+MSS+LE + S+ VP +
Sbjct: 3867 VYEESMNTVLRQELIRFNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAM 3926
Query: 4075 WSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFARK 4134
W+AK+YPSLKPL +V DLL RL F Q WI G P VFWISGF+F Q+FLTG QN+ARK
Sbjct: 3927 WAAKSYPSLKPLGGYVADLLARLTFFQEWIDKGPPVVFWISGFYFTQSFLTGVSQNYARK 3986
Query: 4135 FVISIDTISFDFKVMFEAPSE--LTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELY 4192
+ I ID I F+F+V P E + P+ G YI GLFLEGARWD + Q+ ES PK LY
Sbjct: 3987 YTIPIDHIGFEFEV---TPQETVMENNPEDGAYIKGLFLEGARWDRKTMQIGESLPKILY 4043
Query: 4193 TEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHW 4252
+ +IWL P + QD Y+CP+YKT R GTLSTTGHSTNYV+++E+PT PQ+HW
Sbjct: 4044 DPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKHW 4103
Query: 4253 IKRGVALICALD 4264
I RGVA +C LD
Sbjct: 4104 INRGVASLCQLD 4115
>gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]
Length = 4158
Score = 2708 bits (7019), Expect = 0.0
Identities = 1509/3812 (39%), Positives = 2246/3812 (58%), Gaps = 234/3812 (6%)
Query: 595 KLRKLMELVKYMLQDTLRFLVQDSLASFSQFISDTCCSVLNCTDDMVWGDDLINSPYRPR 654
+L + L Y++++T+ L +++ S ++D + W + P P
Sbjct: 436 RLTCFIRLNDYLIENTMHILTVNAVNSLLNHLTDKLKRTPSADVIQKWITE--EKPEVPD 493
Query: 655 KN---------------PLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATHAVPQ 699
K P+F+ +L+L + + LE F +L + +VP
Sbjct: 494 KKGTLMVEKQEEDESLIPMFLTELMLTVQSLLFEPSLEDFLDGILGAVNHCQNTVLSVPN 553
Query: 700 LEKLVMEDIFISG-------------DPLLESVGLHEP----LVEELRATIASAVSKAMI 742
L D F S P L +V + ++ +++ TI +A A I
Sbjct: 554 LVPDSYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFHTIISQIKETIQAAFESARI 613
Query: 743 PLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLAQEVREVVLTHLRE------KEILDS- 795
YA + K+ F K ++ L A +++E + E K+ D+
Sbjct: 614 ----YAATFEKF--------QIFFKENESLDLQALKLQEPDINFFSEQLEKYHKQHKDAV 661
Query: 796 SLPSSIIIGPFYINTDNVKQSLSKKRKALATSVLDILAKNLHKEVDSICEEFRSISRKIY 855
+L + +G I+T +++ L + +L + K+VD+I E + K+
Sbjct: 662 ALRPTRNVGLLLIDTRLLREKLIPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDAEYKLE 721
Query: 856 EKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASN 915
P + E ++ I ER+ LE+ V Y++M+++ +DF + +
Sbjct: 722 FVPTTTTEYVHSLLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFA---VFAT 778
Query: 916 WPSKILGQIELVQQQHVEDEEKFRKIQI---MDQNNFQEKLEGLQLVVAG---FSIHVEI 969
I+ + + + E ++ + D ++ ++L I +
Sbjct: 779 MKPSIVAVRNAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQ 838
Query: 970 SRAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTT 1029
+ I N ++ V L D Q+ A Y + ++ F + ++ ++ L + E + LW +
Sbjct: 839 DKIRLILNNLQSV---LADLQKRAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDS 895
Query: 1030 ASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIE 1089
S+W + + W+ +D E L V + K V Q + V ++ ++E
Sbjct: 896 FSEWDKLQQEWLKSKFDCLDPEVLNGQVSK----YAKFVTQLEKGLPPNSVVPQLKYKVE 951
Query: 1090 EFKPYIPLIQGLRNPGMRIRHWETLSNQININ-VRPKANLTFARCLEMNLQDHIESISKV 1148
+ K +P+I LRNP ++ RHW + ++ V + LT R ++++ D + I +
Sbjct: 952 KMKEKLPVIIDLRNPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDFGQEIQDI 1011
Query: 1149 AEVAGKEYAIEQALDKMEKEWSTILFNVLPYK-ATDTYILKSPDEASQLLDDHIVMTQNM 1207
+ A E A+E L K+E W T F +LP++ + D +IL D+ LLDD + +
Sbjct: 1012 SGQASGEAALEAILKKVEDSWKTTEFVILPHRDSKDVFILGGTDDIQVLLDDSTINVATL 1071
Query: 1208 SFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQLPVESKRY 1267
+ S Y P + R++ W+ +L L + LEEWL CQR+WLYLE IF++ DI +QLP E+K +
Sbjct: 1072 ASSRYLGPLKTRVDEWQKQLALFNQTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMF 1131
Query: 1268 QTMERIWKKIMKNAYENREVINVCSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPR 1327
+++ WK+IM+ + + +L++ ++ N +LD +QK L YLE+KR FPR
Sbjct: 1132 LQVDKSWKEIMRKVNRLPNALRAATQPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPR 1191
Query: 1328 FYFLSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQ-------------------ED 1368
FYFLS+DELLEIL+QT++P AVQPHLRKCF++I++L F
Sbjct: 1192 FYFLSNDELLEILAQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYT 1251
Query: 1369 LEITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIEKAIRAYPTMPRTQW 1428
+I M S EGE V L + NVE+WL +VE +M S+ + + AI Y RT W
Sbjct: 1252 NDILAMLSPEGERVSLGKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDW 1311
Query: 1429 VL-NWPGQVTIAGCQTYWTMEVAEALEAGNLRS----QLFPQL-CQQLSDLVALVRGKLS 1482
V+ P QV + Q W ++ E LE + + F ++ ++L+ L A+V+G L
Sbjct: 1312 VVAGHPSQVILTVSQIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNALAAIVQGSLP 1371
Query: 1483 RMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNN--DLYIRAVNAE 1540
++ R +L+ALI I+VHA+D+V++L+Q V +V F W QLRYYW + + R ++
Sbjct: 1372 KLHRNILTALITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALSQ 1431
Query: 1541 FIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAI 1600
+ YGYEYLG RLVITPLTDRCYL L GAL L GGAPAGPAGTGKTETTKDL KALAI
Sbjct: 1432 YTYGYEYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAI 1491
Query: 1601 QTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQR 1660
Q VVFNCSD LD+ MG+FF GLA +GAW CFDEFNRIDIEVLSV+AQQ+ TI+ A+ +
Sbjct: 1492 QCVVFNCSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAK 1551
Query: 1661 VERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLY 1720
+ RFMFEG EI LV +CA FITMNPGYAGRTELPDNLKALFRP AMMVP+YA+I E+ LY
Sbjct: 1552 LSRFMFEGREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILY 1611
Query: 1721 SFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELI 1780
S GF + +LA+K+T +KL SEQLS QDHYDFGMRAVK+V+ AG+LKRENP +NE+++
Sbjct: 1612 SEGFESSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVV 1671
Query: 1781 CLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEG 1840
+RA++D N+PKFL +D LFSGI+SDLFP ++ + DYGIL I + NL+
Sbjct: 1672 LIRALQDSNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMC 1731
Query: 1841 FLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYV 1900
+ K IQ YET +VRHG+MLVGPTG GK+T YR+LA + +L+ + I Y+AV YV
Sbjct: 1732 MVRKVIQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQ-KLGIENSFYQAVKTYV 1790
Query: 1901 LNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIENMN 1960
LNPKSITMG+LYGE + LT EW DG+ + +RA + + KW + DGPVDA+WIENMN
Sbjct: 1791 LNPKSITMGELYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDALWIENMN 1850
Query: 1961 TVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIE 2020
TVLDDNK LCL++ E IKLT + M+FEVQDL VASPATVSRCGMV+++P L MP+++
Sbjct: 1851 TVLDDNKMLCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPYVK 1910
Query: 2021 CWLRKLPP-LLKPYEEHFKALFVSFLEESISFVRSSVKEVIASTNCNLTMSLLKLLDCFF 2079
W++ + L + +E+ LF +++E + F+ + I + + +L LL+
Sbjct: 1911 TWMKGISKKLTEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLESLI 1970
Query: 2080 KPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSGRTSFSHWLRLKMENEQ 2139
L ++G+ + +++ ++ F+F +WS+G + SF ++R + ++
Sbjct: 1971 ---LGKDGVNLAMEQ--TKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFDDNP 2025
Query: 2140 LTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVPDTNYCNI 2199
DA + + D ++ W F D + +
Sbjct: 2026 -----------------DARLPNSGDLWSIHMDFDTKRLDPWERIIPTFKYNRDVPFFEM 2068
Query: 2200 IVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDKLLKNL--ALDYISHFLTFS 2257
+VPT DTV+ +L++ LL K VL G TG GK++ I+ LL + + Y+ +L FS
Sbjct: 2069 LVPTTDTVRYGYLMEKLLAVKHSVLFTGITGVGKSV-IAKGLLNKIQESAGYVPVYLNFS 2127
Query: 2258 ARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWM 2317
A+TS+ +TQ+ I+SKL+++RK + G P + + F+DDLNMP L+ YG+QPPIELLRQ+
Sbjct: 2128 AQTSSARTQEIIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQ 2187
Query: 2318 DHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRI 2377
D GG+YDR + +K + D+ + A PPGGGRN VTPR +RHF+ L E S K+I
Sbjct: 2188 DFGGFYDRNKL-FWKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQI 2246
Query: 2378 FSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYT 2437
F IL +L P + +VEA++ +Y ++ LLPTPAKSHY
Sbjct: 2247 FQAILNGFLSDF------------PPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYV 2294
Query: 2438 FNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCM 2497
FNLRDLSK QG+L DP + +++Q+ RL+ HE RVF DRL+N ED+ +F +L
Sbjct: 2295 FNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMA 2354
Query: 2498 EQW-------EVTFNKVCPFQPILYGDFMSPGSDV--KSYELITSESKMMQVIEEYIEDY 2548
+ E NK PI++GDF+ G+D + Y+ + K V+++Y++DY
Sbjct: 2355 NKHFGIAIDLEYFLNK-----PIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDY 2409
Query: 2549 NQINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECF 2608
N N ++KLV F DA+ H+ RI+R +RQ GNALL+GVGG+G+ SLTRLA+H+ Y+C
Sbjct: 2410 NLTNPKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCL 2469
Query: 2609 QIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPN 2668
QIELS+ Y + +D++K+ AG+++ + FLF+DTQI E FLEDINN+LNSG++PN
Sbjct: 2470 QIELSRGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPN 2529
Query: 2669 LYTADEQDQIVSTMRPYIQEQGL-QPTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARL 2727
L+ DE +Q+++ RP +E G+ + + + + +VR +H+VLCMSP+GE FR+R
Sbjct: 2530 LFEKDELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRC 2589
Query: 2728 RQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEI-QGLIQVCVYIHQSVS 2786
R FPSLVNCCTIDWF +WP EAL SV+ F +++ ++ EE+ + L +CV +H SVS
Sbjct: 2590 RMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQV---DAGNEELKEKLPLMCVNVHLSVS 2646
Query: 2787 KKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDV 2846
Y EL R Y TP SYLEL++++ ++ +K+ ++ +A++R+K+GL KLL T+ V
Sbjct: 2647 SMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILV 2706
Query: 2847 AKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIA 2906
KM+ DL ++ P+L ++D ME++ VD A++ RN+VQ +E A KA++ QAIA
Sbjct: 2707 DKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIA 2766
Query: 2907 DDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKV 2966
DDAQ+DLDEALPALDAA +L +L+K D++E+R +PP V V+EA+ I+ KP
Sbjct: 2767 DDAQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKPD-- 2824
Query: 2967 PGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQPYIDNEEFQPATI 3026
W K LL D +FL+ L ++DK+NI ++ +Q YI+N +F P +
Sbjct: 2825 ------------WPSAKQLLGD-SNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKV 2871
Query: 3027 AKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREVED 3086
KVSKAC S+C WVRAM Y V K VEPKRQ L AQ +L +T L E + LR+VED
Sbjct: 2872 EKVSKACKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVED 2931
Query: 3087 GIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQETVENLQYMLNN 3146
I +Q +Y + + +KE L + RL RAGKL L DE+VRW+E+++ + ++N
Sbjct: 2932 QIQALQDEYDKGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISN 2991
Query: 3147 ISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQLRSHNVPHTSEPTLIGTLGNPVKIRSW 3206
I+G+V +AA VAY G FT QYR L + W++ +S +P +LI LG+P +IR W
Sbjct: 2992 ITGNVFIAAACVAYYGAFTAQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQW 3051
Query: 3207 QIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGLDVFKLSDRDFLRS 3266
GLP D +S ENG++ +RW IDPQ QAN+WI+N E +GL + KL+D +FLR
Sbjct: 3052 NTDGLPRDLISTENGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRI 3111
Query: 3267 MENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYITT 3326
+EN+IR G P LLE + E LDPALEP+LLKQ + G +++LGD+ I Y ++FR Y+TT
Sbjct: 3112 LENSIRLGLPVLLEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTT 3171
Query: 3327 KLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLIISNAKMRQE 3386
K+PNPHY PE+ K+T+INFT++ SGLEDQLL VV E+P LEE + +LI+ + +
Sbjct: 3172 KMPNPHYLPEVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQ 3231
Query: 3387 LKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEY 3446
LK IE++IL L +SEGN +D+ ELI L+ SK+ + I+ ++ AE TE+ I++ R +Y
Sbjct: 3232 LKTIEEKILRMLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKY 3291
Query: 3447 IPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLKKRISNINRYLT 3506
PVA + +++F ++ L+ +DPMYQYSL++F +F + I S + +NL++R+ +
Sbjct: 3292 RPVATQGSVMYFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTL 3351
Query: 3507 YSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLLSGGSISIMTENPAPD-- 3564
+ Y NV R LFE+HKL+++F+LCV +M +G ++ +EW + L G + P P+
Sbjct: 3352 LTAYVNVSRGLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAP 3411
Query: 3565 WLSDRAWRDILAL-SNLPTFSSFSSDFVKH-----LSEFRVIFDSLE------------- 3605
WL W L + P F + + + H L F + +
Sbjct: 3412 WLPTATWFACCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKH 3471
Query: 3606 -------PHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTA 3658
H++P W L F KL++++C + +KV A+ DFV NL +FIE
Sbjct: 3472 MRQEKEAAHQDP----WSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPV 3527
Query: 3659 NLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMR 3718
+L +++D + TPL+F+LS G+DP +FA E +S+++ +ISLGQGQGP AE M++
Sbjct: 3528 DLPTLYQDMSCNTPLVFILSTGSDPMGAFQRFARESGYSERVQSISLGQGQGPIAEKMVK 3587
Query: 3719 SSIERGKWVFFQNCHLAPSWMPALERLIE-HINPDKVHRD-FRLWLTSLPSNKFPVSILQ 3776
+++ G WVF QNCHLA SWM A+E LI+ +PD +D FRL+L+S+PSN FPV++LQ
Sbjct: 3588 DAMKSGNWVFLQNCHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQ 3647
Query: 3777 NGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGP 3836
N K+T EPP+G+RAN+ ++++ + F +++ ++ +C FH ER+KFGP
Sbjct: 3648 NSVKVTNEPPKGLRANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGP 3707
Query: 3837 LGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMN 3896
LG+NI YEF D D + LK++ E IP+ L Y GEI YGGRVTD WD+RC+
Sbjct: 3708 LGWNICYEFNDSDRECALLNLKLYCKE-GKIPWDALIYITGEITYGGRVTDSWDQRCLRT 3766
Query: 3897 ILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANIT 3956
IL+ F++P+ L ++ YS SGIY P L + YI++LPL D PEIFG+H+NAN+
Sbjct: 3767 ILKRFFSPETLEEDYKYSESGIYF-APMADSLQEFKDYIENLPLIDDPEIFGMHENANLV 3825
Query: 3957 FAQNETFALLGTIIQLQPKSSSAG-SQGREEIVEDVTQNILLKVPEPINLQWVMAKYPVL 4015
F ET L+ TI+++QP+SS+ G + +EIV+++ ++ +VPE + ++ V
Sbjct: 3826 FQYKETSTLINTILEVQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVK 3885
Query: 4016 YEE----SMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTV 4071
+ S+ TVL QEV R+N LL++I +L+ L KA+ G VVMS ++E + S NN V
Sbjct: 3886 DLQGRLNSLTTVLGQEVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQV 3945
Query: 4072 PELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNF 4131
P LWS AYPSLKPL SWV DL+ R F+ W++ G P +WISGFFFPQ FLTGTLQN
Sbjct: 3946 PALWSNTAYPSLKPLGSWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTGTLQNH 4005
Query: 4132 ARKFVISIDTISFDFKVM-------------------FEAPSEL-TQRPQVGCYIHGLFL 4171
ARK+ + ID +SF + V+ E P ++ P+ G +HG+F+
Sbjct: 4006 ARKYNLPIDELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFM 4065
Query: 4172 EGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTT 4231
+ +RWD + + ++ P ++ + V+ P N K Y CP+YKT RAGTLSTT
Sbjct: 4066 DASRWDDKEMVIEDALPGQMNPVLPVVHFEPQQNYK-PSPTLYHCPLYKTGARAGTLSTT 4124
Query: 4232 GHSTNYVIAVEIPTHQPQRHWIKRGVALICAL 4263
GHSTN+V+ V +P+ + + +WI +G AL+C L
Sbjct: 4125 GHSTNFVVTVLLPSKRSKDYWIAKGSALLCQL 4156
>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
Length = 4427
Score = 2520 bits (6532), Expect = 0.0
Identities = 1441/3777 (38%), Positives = 2170/3777 (57%), Gaps = 179/3777 (4%)
Query: 541 EFEQIQSQTFSQVQMFLKDSWISSLKVAMRSSLRDMSKGWYNLYETNWEVYLMSKLRKLM 600
EFE+ Q + + VQ L + + V + ++ ++ K + W +Y++ R
Sbjct: 776 EFEEDQREHRAAVQQKLMN--LHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDR--- 830
Query: 601 ELVKYMLQDTLRFLVQDSLASFSQFISDTCCSVLNCTDDMVWGDDLINSPYRPRKNPLFI 660
M++D LR V+ SL S+ IN + NPLF
Sbjct: 831 -----MMEDALRLNVKWSLLELSK---------------------AINGDGKTSPNPLFQ 864
Query: 661 MDLVLDS------SGVHYSTPLEQFEASLLNLFDKGILATHAVPQLEKLVMEDIFISGDP 714
+ ++L + + V +S L+ A ++N + +T +V ++ + +P
Sbjct: 865 VLVILKNDLQGSVAQVEFSPTLQTL-AGVVNDIGNHLFSTISVFCHLPDILTKRKLHREP 923
Query: 715 LLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGL 774
+ V E +++++ I+S ++ LQ Y K + Y E+ + SF+ YQ
Sbjct: 924 IQTVVEQDED-IKKIQTQISSGMTNNASLLQNYLKTWDMYREIWEINKDSFIHRYQR--- 979
Query: 775 LAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTD------NVKQSLSKKRKALATSV 828
L V V R E+ ++ + ++ D ++ Q ++ + AT +
Sbjct: 980 LNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFATLL 1039
Query: 829 LDILAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLVGLEERIVKV 888
++ A L + + E ISR P ++EEL + + + L +E +I +
Sbjct: 1040 REMAAGRLLELHTYLKENAEKISRP----PQTLEELGVSLQLVDALKHDLANVETQIPPI 1095
Query: 889 MDDYQVMDEFLYNLSS------DDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQ 942
+ + +++++ + D N +W+ + +L +++++ +EKF+
Sbjct: 1096 HEQFAILEKYEVPVEDSVLEMLDSLNGEWVV--FQQTLLDSKQMLKKH----KEKFKTGL 1149
Query: 943 IMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIA-NEVRRVKKQLKDCQQLAMLYNNRER 1001
I ++F++K L L F H + + A +++ +V+ L ++
Sbjct: 1150 IHSADDFKKKAHTL-LEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLRANLG 1208
Query: 1002 IFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAF 1061
IF + L + KE +W A DW W + E +E F
Sbjct: 1209 IFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLF 1268
Query: 1062 KTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININ 1121
+ + K K++KD E+ R++IE+FK +PLI LRNP +R RHW+ + ++I
Sbjct: 1269 RRLTKLAKEYKDRN--WEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQRE 1326
Query: 1122 VRPKA-NLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYK 1180
++ + T + +E+ + H+E I +++ A KE AIE AL + K W +++PYK
Sbjct: 1327 FDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYK 1386
Query: 1181 ATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNC 1240
+ L+ +E Q L+D+ V M S + K FE+ ++ WE L L EV+E L
Sbjct: 1387 DKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTV 1446
Query: 1241 QRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDSL 1300
QR W+YLE IF EDI +QLP ES + + WK IM ++ + +LD+L
Sbjct: 1447 QRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTL 1506
Query: 1301 RDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENI 1360
+ N IL+ +QK L YLETKR FPRFYFLS+D+LLEIL Q+++P AVQPHL+KCF+NI
Sbjct: 1507 IEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNI 1566
Query: 1361 ARLLFQE------DLEITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIE 1414
L Q+ E M+S +GE + S++ VE WL +VE++M+ ++ D++
Sbjct: 1567 KLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLR 1626
Query: 1415 K---AIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLRSQ------LFPQ 1465
A+R + R +WV W GQV I Q WT +V + L R+ +
Sbjct: 1627 NCHLALRKFLNK-RDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKN 1685
Query: 1466 LCQQLSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRY 1525
L+ +RG L+++ R + AL+ IE+HA+DV+ KL + ++ VN F W+SQLR+
Sbjct: 1686 QVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRF 1745
Query: 1526 YWTNN--DLYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPA 1583
YW + D IR N +F Y YEYLGNSGRLVITPLTDRCY+TLT ALHL GG+P GPA
Sbjct: 1746 YWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPA 1805
Query: 1584 GTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVL 1643
GTGKTET KDLGKAL I +V NCS+ LD+ +MG+ + GLA GAW CFDEFNRI+IEVL
Sbjct: 1806 GTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVL 1865
Query: 1644 SVVAQQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRP 1703
SVVA QI I A + F F+G EI LV SC +FITMNPGYAGRTELP+NLK++FRP
Sbjct: 1866 SVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRP 1925
Query: 1704 VAMMVPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVIS 1763
+AM+VPD +I EI L+ GF +LAKK+ T + L+ +QLS QDHYDFG+RA+ +++
Sbjct: 1926 IAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLR 1985
Query: 1764 AAGNLKRENPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILD 1823
AG +R P + +E + L ++RD+N+ K D LF+ IV DLFP I+ DYG L
Sbjct: 1986 YAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLR 2045
Query: 1824 EAIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSL- 1882
E + + R+ L+ LTK QLYET RH M+VG TGSGK+ +R+L A+++SL
Sbjct: 2046 ETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLC 2105
Query: 1883 -KGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTN 1941
G P+ + V + LNPK++++G+LYGE+DL T+EWTDGI SS +R +
Sbjct: 2106 RAGDPN-----FNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPD 2160
Query: 1942 KKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVS 2001
+KW +FDGPVD +WIENMN+V+DDNK L L +GE I + E ++++FEV+DLA+ASPATVS
Sbjct: 2161 EKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVS 2220
Query: 2002 RCGMVYLEPSILGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEESISFVRSSVKEVIA 2061
RCGMVY + + LG P+++ WL K P K E + +F + + ++F + + KE++
Sbjct: 2221 RCGMVYTDYADLGWKPYVQSWLEKRP---KAEVEPLQRMFEKLINKMLAFKKDNCKELVP 2277
Query: 2062 STNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDS 2121
+ SL KL P G+ E V ++E F+FS+IWSV A+ D
Sbjct: 2278 LPEYSGITSLCKLYSAL---ATPENGVNPADGE---NYVTMVEMTFVFSMIWSVCASVDE 2331
Query: 2122 SGRTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVKW 2181
GR +LR ++ FP + V++Y ++ K +W +
Sbjct: 2332 EGRKRIDSYLR------EIEGSFPNKDTVYEYFVDP----------------KIRSWTSF 2369
Query: 2182 MDS-SAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDK 2240
D + P+ + I+VPT+DTV+ ++L+ L+ N+ P+L +GP GTGKT +I+
Sbjct: 2370 EDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVGPVGTGKT-SIAQS 2428
Query: 2241 LLKNLALDYISHF-LTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMP 2299
+L++L S + SA+T++N Q I+S+++KR KGV+ P G++ I F+DDLNMP
Sbjct: 2429 VLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGKSMITFMDDLNMP 2488
Query: 2300 ALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMR 2359
A + +G+QPP+EL+R W+D+G WYDR K + ++ + AMGPPGGGR ++PRL
Sbjct: 2489 AKDMFGSQPPLELIRLWIDYGFWYDR-TKQTIKYIREMFLMAAMGPPGGGRTVISPRLRS 2547
Query: 2360 HFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMV 2419
FN ++ + RIF T++ L + + E V ++ + EAT+ +
Sbjct: 2548 RFNIINMTFPTKSQIIRIFGTMINQKL------QDFEEEVKPIGNV------VTEATLDM 2595
Query: 2420 YATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDR 2479
Y T+ + LPTP K HY FNLRD+SKVFQGML A+ + + + RLW HE RVF DR
Sbjct: 2596 YNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDR 2655
Query: 2480 LVNEEDRSWFDQLLK-RCMEQWEVTFNKVCPF-QPILYGDFMSPGSDVKSYELITSESKM 2537
LV+ D F ++ + +++TF+ +CP +P ++GDF+ + K YE +T + +
Sbjct: 2656 LVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFL---KEPKVYEDLTDLTVL 2712
Query: 2538 MQVIEEYIEDYN-QINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLT 2596
V+E + +YN + ++LVLF +A+ HI RI R + Q GN LL+G+GGSGR SL
Sbjct: 2713 KTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLA 2772
Query: 2597 RLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLED 2656
RLAS + +Y FQIE++K+Y E+RDD+K++ +AG++ +F+F DTQI +ESFLED
Sbjct: 2773 RLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLED 2832
Query: 2657 INNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCM 2716
INN+L+SG++PNLY DE ++I S + + + + + +L A RV++N+H+VLC+
Sbjct: 2833 INNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNNLHIVLCL 2892
Query: 2717 SPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQ 2776
SP+G+ FR +RQ+P+LVNC TI+WF+EWP EAL VA L + +L + + + + Q
Sbjct: 2893 SPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGV-DLGTQENIHRKVAQ 2951
Query: 2777 VCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGL 2836
+ V +H SV++ + L EL RHNYVTP YLELL + L+G+K+ EL N++++GL
Sbjct: 2952 IFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGL 3011
Query: 2837 DKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKAN 2896
K+ T E V M +LE + E K + I A+E + +V K
Sbjct: 3012 FKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIA 3071
Query: 2897 EKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVC 2956
+ K QA+AD+AQKDL+EALPAL+ A+ +L +LNK D+ E+++ RPP V++V++AV
Sbjct: 3072 VEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVM 3131
Query: 2957 IMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQPYI 3016
I++G +P W K L + +F++SL FDKDNI D V+K I Y
Sbjct: 3132 ILRGNEPT--------------WAEAKRQLGEQ-NFIKSLINFDKDNISDKVLKKIGAYC 3176
Query: 3017 DNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDE 3076
+FQP I +VS A S+C WVRAM Y + + VEPKR + A L Q L E
Sbjct: 3177 AQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAE 3236
Query: 3077 AKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQET 3136
A+++LREV + + ++ +Y E + +KEEL K E+ E +L RAG L++GL+ EK RW+ET
Sbjct: 3237 AQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEET 3296
Query: 3137 VENLQYMLNNISGDVLVAAGFVAYLGPFTGQYR-TVLYDSWVKQLRSHNVPHTSEPTLIG 3195
V+ L+ L + GD L+AA F++Y+GPF YR ++ W+ ++ VP + +
Sbjct: 3297 VQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDN 3356
Query: 3196 TLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGLDV 3255
L NP K+R W I GLP+D S ENG+I RW IDPQ+QA KWIKNME GL +
Sbjct: 3357 FLCNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKI 3416
Query: 3256 FKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIP 3315
L D+LR +E+AI FG P LL+NV E LDP L P+L K + G ++++GD +
Sbjct: 3417 IDLQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVE 3476
Query: 3316 YHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQ 3375
Y+ +FR YITTKL NPHY+PE S K T++NF + GLE QLLG VV +ERP+LEE K+
Sbjct: 3477 YNTNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDS 3536
Query: 3376 LIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQT 3435
L+I+ A +++LK++ED+IL L+ + G+ +DD++L+ L SK+ A E+ ++ +E T
Sbjct: 3537 LVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETT 3596
Query: 3436 EKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLK 3495
E + DL R Y P A R ILFF ++D+ +DPMYQ+SL+ ++++F+ I S R++ L+
Sbjct: 3597 EINTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLE 3656
Query: 3496 KRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLLSGGSI- 3554
RI +N Y TY++Y CR+LFE+HKL+F+F +C +I+ GK+N E+ + L GG +
Sbjct: 3657 DRIDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVL 3716
Query: 3555 --SIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHREPLP 3612
+NP WL+D W +I L L F + F ++ ++ + + + P + LP
Sbjct: 3717 DREGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLP 3776
Query: 3613 GIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTP 3672
G W+ ++ Q++L++R LR D+V + F+ TNL RFIEP N+ V +DS +P
Sbjct: 3777 GEWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSP 3836
Query: 3673 LIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNC 3732
L+F+LSPG DP + L + AE M +++ A+SLGQGQ P A ++R + +G WVF NC
Sbjct: 3837 LVFILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANC 3896
Query: 3733 HLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVRAN 3792
HL+ SWMP L++L+E + + H FRLWL+S+P FP+SILQ KMT EPP+G++AN
Sbjct: 3897 HLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKAN 3956
Query: 3793 LLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRI 3852
+ + Y + E + C K ++K LL SLC FH LER+KF LG+NI Y F D D +
Sbjct: 3957 MTRLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEV 4016
Query: 3853 CISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLS-PEH 3911
+ L ++LDEY++ P+ LKY INYGG VTDDWDRR + + D++ LS P H
Sbjct: 4017 SENLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFH 4076
Query: 3912 SYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQ 3971
SA Y IP L Y YI LP D PE FG H NA++ E L T++
Sbjct: 4077 RLSALETYF-IPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLS 4135
Query: 3972 LQPK--SSSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVI 4029
LQP+ + AG Q REE V ++ ++ K+PE I+ + K L +N VL+QE+
Sbjct: 4136 LQPQITPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQ-KLLALDPSPLNVVLLQEIQ 4194
Query: 4030 RYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSW 4089
RYN L+Q I +L DL K ++GL+VMS+ LE + +++ VP LW KAYPS KPL++W
Sbjct: 4195 RYNTLMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLW-GKAYPSQKPLAAW 4253
Query: 4090 VMDLLQRLDFLQAWIQDG-IPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKV 4148
DL R++ + W P +FW+SGF FP FLT LQ+ AR+ +S+D++S++F V
Sbjct: 4254 TRDLAMRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIV 4313
Query: 4149 MFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKA 4208
S L P+ G ++ GL+LEGA WD + L E++P +L M I P +RK
Sbjct: 4314 STVDDSNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKK 4373
Query: 4209 QDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPT-HQPQRHWIKRGVALICALD 4264
+ Y CP Y RAG + ++VI +++ + HWIKRG AL+ +LD
Sbjct: 4374 SAKGMYSCPCYYYPNRAG----SSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLD 4426
>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
Length = 4471
Score = 2093 bits (5424), Expect = 0.0
Identities = 1236/3607 (34%), Positives = 1978/3607 (54%), Gaps = 177/3607 (4%)
Query: 724 PLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLAQEVREVV 783
P + E I V + +I L Y +++++Y L D A ++ + ++
Sbjct: 966 PQIIEQAVMIPQNVHRILINLMKYLQKWKRYRPLWKLDKAIVMEKFAA--------KKPP 1017
Query: 784 LTHLREKEILDSSLPSSIIIGPFY-------INTDNVKQSLSKKRKALATSVLDILAKNL 836
EK S + ++ P + ++ ++ + K+ S+ +L ++
Sbjct: 1018 CVAYDEKLQFYSKIAYEVMRHPLIKDEHCIRLQLRHLANTVQENAKSWVISLGKLLNESA 1077
Query: 837 HKEVDSICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMD 896
+E+ ++ EE +++ + + PN++E+L + + I + + +E R V + Y+ M
Sbjct: 1078 KEELYNLHEEMEHLAKNLRKIPNTLEDLKFVLATIAEIRSKSLVMELRYRDVQERYRTMA 1137
Query: 897 EFLYNLSSDDFNDKW---IASNWPSKI---------LGQIELVQQQHVEDEEKFRKIQIM 944
+YNL D + I S W + LG I+ + E ++QI
Sbjct: 1138 --MYNLFPPDAEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIE 1195
Query: 945 DQNNFQEKL--EGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQLAMLYNNRERI 1002
+ F ++ EG V VE+ +E R + + K Q+LA N E++
Sbjct: 1196 E---FAKRFYSEGPGSVGDDLDKGVELLGVYE-----RELARHEKSRQELA----NAEKL 1243
Query: 1003 FSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFK 1062
F LPIT Y +L ++ KE ++ E W ++ + L++ + +
Sbjct: 1244 FDLPITMYPELLKVQKEMSGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLR 1303
Query: 1063 TMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININV 1122
+ K + + + V + A+++ FK IPL+ L+N +R RHW+ L + ++
Sbjct: 1304 ALRKLPRPVRGL----SVTYYLEAKMKAFKDSIPLLLDLKNEALRDRHWKELMEKTSVFF 1359
Query: 1123 RPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPY-KA 1181
T M L H + ++++ A KE AIE+A+ ++ W + F V+ Y K
Sbjct: 1360 EMTETFTLENMFAMELHKHTDVLNEIVTAAIKEVAIEKAVKEILDTWENMKFTVVKYCKG 1419
Query: 1182 TDT--YILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLN 1239
T YIL S DE Q LDD+ Q++S S + PF Q ++ WE L L EV+E W+
Sbjct: 1420 TQERGYILGSVDEIIQSLDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWML 1479
Query: 1240 CQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDS 1299
QR W+YLE IF DI QLP E+K++ +++++K+IM ++ + C L
Sbjct: 1480 VQRKWMYLESIFIGGDIRSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSD 1539
Query: 1300 LRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFEN 1359
L++ ++ L+ QK L++YL++KR+AFPRF+F+SDDELL IL + DP VQ H+ K ++N
Sbjct: 1540 LQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSS-DPLCVQEHMIKMYDN 1598
Query: 1360 IARLLFQE----DLEITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIEK 1415
IA L F + + ++ M SAEGE ++ + VEDW+ V M+ + I ++
Sbjct: 1599 IASLRFNDGDSGEKLVSAMISAEGEVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKE 1658
Query: 1416 AIRAY-PTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGN-----LRSQLFPQLCQQ 1469
AI Y R W+L + G V +A Q +WT EV + ++ +Q
Sbjct: 1659 AIFRYCEDRSRVDWMLLYQGMVVLAASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQ 1718
Query: 1470 LSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTN 1529
+ +LV + LS+ R + +++I+VHA+D+V I+ +++ +F W SQLR+YW
Sbjct: 1719 IDELVTRITMPLSKNDRKKYNTVLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDR 1778
Query: 1530 --NDLYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGK 1587
++L IR F YGYEY+G +GRLVITPLTDR YLTLT AL + GGAPAGPAGTGK
Sbjct: 1779 EPDELNIRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGK 1838
Query: 1588 TETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVA 1647
TETTKDL KAL + VV NC + +D+ A+GK F GLA GAW CFDEFNRID VLSV++
Sbjct: 1839 TETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVIS 1898
Query: 1648 QQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMM 1707
QI TI+ A ++ F FEG EI L +FITMNPGYAGRTELP+++KALFRPV ++
Sbjct: 1899 SQIQTIRNALIHQLTTFQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVI 1958
Query: 1708 VPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGN 1767
VPD I EI L+S GF EA LAKK+T +KL+ EQLS Q HYDFG+RA+K+V+ AG
Sbjct: 1959 VPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGE 2018
Query: 1768 LKRENPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIR 1827
LKR + + E+++ +RA+RD+N+PKF+ ED+ LF G++SDLFP + Y ++A+
Sbjct: 2019 LKRGSSDLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVE 2078
Query: 1828 EACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPS 1887
+ + + + K +Q++ET + RH M+VGPT GKS L A T L
Sbjct: 2079 QVLEENGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRGGKSVVINTLCQAQTKL----- 2133
Query: 1888 ISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIR-AGAITSDTNKKWYM 1946
G+ Y+LNPK++++ +LYG D T +WTDG+ S+ R T +K+ +
Sbjct: 2134 ---GL--TTKLYILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREINKPTDKKERKYIL 2188
Query: 1947 FDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMV 2006
FDG VDA+W+ENMN+V+DDN+ L L++GE I+L ++FEV DL ASPATVSRCGMV
Sbjct: 2189 FDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFEVGDLQYASPATVSRCGMV 2248
Query: 2007 YLEPSILGLMPFIECWLRKLPPLLKPYE-----EHFKALFVSFLEESISFVRSS--VKEV 2059
Y++P L P+ + W+ ++P ++ Y E + + + E I R + +K +
Sbjct: 2249 YVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLFEKYVPYLMDVIVEGIVDGRQAEKLKTI 2308
Query: 2060 IASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATG 2119
+ T+ N+ L K+LD E ++L+E +F+ +L S+GA+
Sbjct: 2309 VPQTDLNMVTQLAKMLDALL--------------EGEIEDLDLLECYFLEALYCSLGASL 2354
Query: 2120 DSSGRTSFSHWLR----LKMENEQLTLLFPEE-----GLVFDYRLEDAGISGTNDSEDEE 2170
GR F +++ L + + P E ++D+ ++
Sbjct: 2355 LEDGRMKFDEYIKRLASLSTVDTEGVWANPGELPGQLPTLYDFHFDN------------- 2401
Query: 2171 EEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTG 2230
K+ WV W + P+ + NI+V T+DT + + +L+ ++ K+PV+ +G +G
Sbjct: 2402 ---KRNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVGESG 2458
Query: 2231 TGKTLTISDKLLKNLALD-YISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNF 2289
T KT T + LKNL+ + I + FS+RT++ Q +++ ++KR K +GPP+G+
Sbjct: 2459 TSKTAT-TQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKRL 2517
Query: 2290 IFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGG 2349
+ F+DD+NMP ++ YG Q PI LL+ ++ G YDR K++ D+ F+ AMG GGG
Sbjct: 2518 LVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGGG 2577
Query: 2350 RNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFT 2409
RN V PR + F+ + E S I+S+IL ++ E I +
Sbjct: 2578 RNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKG------HTSTFHE------SIVAVS 2625
Query: 2410 EPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWY 2469
L T+ +Y I L PTP+K HY FNLRDLS+VF G+++ +P + + Q++R+W
Sbjct: 2626 GKLTFCTLALYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWR 2685
Query: 2470 HENCRVFRDRLVNEEDRSWFDQLLKRCMEQWEVTFNKVCPFQPILYGDFMSP--GSDVKS 2527
+E RVF DRL++E D+ Q + + + +V PIL+GDF + +
Sbjct: 2686 NECLRVFHDRLISETDKQLVQQHIGSLVVEHFKDDVEVVMRDPILFGDFQMALHEGEPRI 2745
Query: 2528 YELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGV 2587
YE I + +E +E+YN+ NT K+ LVLF DA+ H+ R+ R +R G+ALL+GV
Sbjct: 2746 YEDIQDYEAAKALFQEILEEYNESNT-KMNLVLFDDALEHLTRVHRIIRMDRGHALLVGV 2804
Query: 2588 GGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQ 2647
GGSG+ SL+RLA+ A E F+I LS+ Y + +R+D+K + LK G++N + FLF+D
Sbjct: 2805 GGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAH 2864
Query: 2648 IKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVR 2707
+ E FLE INN+L SG +P L++ +E++ I+S + +QG+ P K ++ + +
Sbjct: 2865 VAEEGFLELINNMLTSGIVPALFSEEEKESILSQIGQEALKQGMGPAKESVWQYFVNKSA 2924
Query: 2708 SNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESS 2767
+N+H+VL MSP+G+ R R FP +VN IDWF WP +AL +VA FL P + +
Sbjct: 2925 NNLHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPA- 2983
Query: 2768 QEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKT 2827
E I+ +++ V +HQSV ++L +L R NYVTPK+YL+ ++ +S L+ +K
Sbjct: 2984 -ENIENVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIA 3042
Query: 2828 AKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNS 2887
R+ GLDKL + + ++ + L +L E + +E+I V+TA+AEE +
Sbjct: 3043 QCKRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKL 3102
Query: 2888 VQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPG 2947
+ + ++ E+ K +A+ L E +P L+AA L+ L+K+DVTE+R+ +PP
Sbjct: 3103 AEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQ 3162
Query: 2948 VKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDV 3007
V+ V E + IMKG K W+ KG++ DP +FL SL + D D+I
Sbjct: 3163 VQTVCECILIMKGYKELN-------------WKTAKGVMSDP-NFLRSLMEIDFDSITQS 3208
Query: 3008 VIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDL 3067
+K I+ + + VSKA + ++V A+ Y V + ++PKR+ + + +
Sbjct: 3209 QVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNF 3268
Query: 3068 GVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLS 3127
+T+R L+ + L ++ + T+ AKY I +K++L+ + E E+RL A KLI+GL
Sbjct: 3269 YLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLG 3328
Query: 3128 DEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDS-WVKQLRSHNVP 3186
E +RW ++ L + + GD L+ A F++Y G FT ++R + + W + +P
Sbjct: 3329 SENIRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDILEREIP 3388
Query: 3187 HTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKN 3246
+ L L + V+I W GLP D LSV+NG++ + R+ IDPQ QA WIK
Sbjct: 3389 LSQPFRLESLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKR 3448
Query: 3247 MEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTV 3306
E+ N L V +D DFL+ +E +I++G P L +V E +DP ++ VL K QG
Sbjct: 3449 KEEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQF 3508
Query: 3307 LKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEER 3366
+ LGD + Y +FR+Y+ TKL NP Y+P + K +IN+T++ GLEDQLL +VA ER
Sbjct: 3509 IILGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYER 3568
Query: 3367 PDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQ 3426
+LEE + LI ++ + LKD+ED +L L++S GN +D+++L+ LE +K KA E+
Sbjct: 3569 RELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVS 3628
Query: 3427 AKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIA 3486
K+++AE+T DID R Y P A R ILFF +S++A V+ MYQYSL FL +F +
Sbjct: 3629 EKLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLK 3688
Query: 3487 NSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWR 3546
S L KR+ NI LT+S+Y++ C LFE+HKL+F+F + ++I EG++ Q E
Sbjct: 3689 KSLPDSILMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELD 3748
Query: 3547 YLLSGGSISIMTENPAP-DWLSDRAWRDILALSNL--PTFSSFSSDFVKHLSEFRVIFDS 3603
+ L G ++ P WLSD+ W DI+ LS + F D + + ++ +D
Sbjct: 3749 FFLKGNISLEKSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWYDL 3808
Query: 3604 LEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVV 3663
+ P+P +D + FQKLL+LRC R D+V A+ D+V + ++++P + +
Sbjct: 3809 DSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEAI 3868
Query: 3664 FKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKF-SKKLSAISLGQGQGPRAEAMMRSSIE 3722
F+ S +P++F+LSPG+DPA DL K AE F +L +++GQGQ A ++ +++
Sbjct: 3869 FEQSTPHSPIVFILSPGSDPATDLMKLAERSGFGGNRLKFLAMGQGQEKVALQLLETAVA 3928
Query: 3723 RGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMT 3782
RG+W+ QNCHL W+ LE+ +E I K H DFRLWLT+ P+ FP+ ILQ K+
Sbjct: 3929 RGQWLMLQNCHLLVKWLKDLEKSLERIT--KPHPDFRLWLTTDPTKGFPIGILQKSLKVV 3986
Query: 3783 IEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIP 3842
EPP G++ N+ +Y + + L+ C FK L+ L FH ERRKFG +G+N+
Sbjct: 3987 TEPPNGLKLNMRATYFKISHEMLDQCPH-PAFKPLVYVLAFFHAVVQERRKFGKIGWNVY 4045
Query: 3843 YEFTDGDLRICISQL-----KMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNI 3897
Y+F + D ++C+ L K F IP+ LKY GE+ YGGR D +DRR +
Sbjct: 4046 YDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIY 4105
Query: 3898 LEDFYNP---DVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNAN 3954
++++ D P H + + ++IP + ++ I++LPL + PE+FGLH NA
Sbjct: 4106 MDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGLHPNAE 4165
Query: 3955 ITFAQNETFALLGTIIQLQPKSSSAGSQ-GREEIVEDVTQNILLKVPEPINLQWVMAKYP 4013
I + + +++LQP++ + S R++ + V + I K+P+ +L V +
Sbjct: 4166 IGYYTQAARDMWAHLLELQPQTGESSSGISRDDYIGQVAKEIENKMPKVFDLDQVRKRLG 4225
Query: 4014 VLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPE 4073
+ + VL+QE+ R+N+L+ +T++L +L +AL G V MS++L+ +A SL+ +P
Sbjct: 4226 TGLSPT-SVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARSLFIGHIPN 4284
Query: 4074 LWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFAR 4133
+W A +LK L +W++ L+R W+ + P+V W+SG P+++LT +Q R
Sbjct: 4285 IWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPSVMWLSGLHIPESYLTALVQATCR 4344
Query: 4134 KFVISID-TISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELY 4192
K +D + F F+ E+ +R GC++ GL+LEGA WD E L +S+PK L
Sbjct: 4345 KNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKGCLIKSKPKVLV 4404
Query: 4193 TEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHW 4252
++ ++ ++P + + Q+ + P+Y T R + V ++ T + HW
Sbjct: 4405 VDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAM-----GVGLVFEADLFTTRHISHW 4459
Query: 4253 IKRGVAL 4259
+ +GV L
Sbjct: 4460 VLQGVCL 4466
>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
Length = 4490
Score = 2031 bits (5261), Expect = 0.0
Identities = 1230/3606 (34%), Positives = 1949/3606 (54%), Gaps = 170/3606 (4%)
Query: 726 VEELRATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLAQEVREVVLT 785
+ +L ++S+V+ ++++KY L D +K + E+R +L
Sbjct: 982 ISKLVLLLSSSVNSLRKAAHEALQDFQKYKTLWTEDRDVKVKEFLANNPSLTEIRSEILH 1041
Query: 786 HLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKKRKALATSVLDILAKNLHKEVDSICE 845
+ ++ +D P I++G ++T+ +K +LS + KA + L + K++ +
Sbjct: 1042 YATFEQEIDELKPI-IVVGALELHTEPMKLALSIEAKAWKMLLCRYLNEEYKKKMSYMIA 1100
Query: 846 EFRSISRKIYEKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLYNLSSD 905
+K+ ++++ E + I + + ++ + + + Y +++ F ++ +
Sbjct: 1101 FINEYLKKLSRPIRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKE 1160
Query: 906 DFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSI 965
+ +K+ + VQ+ V+ + KF+ +N E +E + V F+
Sbjct: 1161 ESEAVDTLRYSFNKLQSKAVSVQEDLVQVQPKFK-------SNLLESVEVFREDVINFAE 1213
Query: 966 HVEISRA-------HEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVK 1018
E+ E +N ++ + D + + Y++ E++F LP+T+Y+ L + K
Sbjct: 1214 AYELEGPMVPNIPPQEASNRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRK 1273
Query: 1019 EFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQ 1078
E L+ + + +D E++ ++E K K KD A
Sbjct: 1274 ELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAF- 1332
Query: 1079 EVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFAR-CLEMN 1137
LD++ RI++F PL++ + N M+ RHW+ +S +++ R +E
Sbjct: 1333 ---LDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAP 1389
Query: 1138 LQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKATDTYILKSPD--EASQ 1195
L H + I + A KE IE L ++ + W+ + +K +LK + E
Sbjct: 1390 LLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIIT 1449
Query: 1196 LLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSED 1255
L++D +++ ++ + Y PF++ I +W KL + +++EEWL Q W+YLE +F D
Sbjct: 1450 LMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGD 1509
Query: 1256 INQQLPVESKRYQTMERIWKKIMKNAYENREVINVC-SDLRMLDSLRDCNKILDLVQKGL 1314
I +QLP E+KR+Q +++ W KIM+ A+EN VIN C D M L ++ L++ QK L
Sbjct: 1510 IAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSL 1569
Query: 1315 SEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQ-EDLE-IT 1372
+ YLE KR FPRF+F+SD LLEIL Q D +QPHL +NI + F +D + I
Sbjct: 1570 TGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRIM 1629
Query: 1373 HMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIEKAI-----RAYPTMPRTQ 1427
+ S EGE++ L S+ VE WL ++ + +S+H+II A + +P
Sbjct: 1630 AVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLP--- 1686
Query: 1428 WVLNWPGQVTIAGCQTYWTMEVAEALEAGNLRSQLFPQLCQQLSD----LVALVRGKLSR 1483
++ ++P QV + G Q WT + EAL ++ Q+ D L++ LS+
Sbjct: 1687 FLSHFPAQVGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSK 1746
Query: 1484 MQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNN--DLYIRAVNAEF 1541
R LI I VH +D+ L++ ++ S DF+W+ Q R+Y+ + + + +F
Sbjct: 1747 FDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDF 1806
Query: 1542 IYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQ 1601
IY E+LG + RLVITPLTDRCY+TL AL + GGAPAGPAGTGKTETTKD+G+ L
Sbjct: 1807 IYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKY 1866
Query: 1602 TVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQRV 1661
VVFNCSDQ+DF +G+ FKGLA +G+W CFDEFNRI++ VLSV AQQI + A+++R
Sbjct: 1867 VVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERK 1926
Query: 1662 ERFMF-EGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLY 1720
++F+F +G + L P +F+TMNPGYAGR ELP+NLK FR VAMMVPD +I + L
Sbjct: 1927 KQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLA 1986
Query: 1721 SFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELI 1780
S GF E +LA+K +KL EQL+ Q HYDFG+R + +V+ G+ KR P +E I
Sbjct: 1987 SCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSI 2046
Query: 1781 CLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEG 1840
+R +RD+N+ K + ED LF +++DLFP ++ + Y L A+ + L +
Sbjct: 2047 VMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINHPP 2106
Query: 1841 FLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYV 1900
+ K +QLYET++VRHGLM +GP+GSGK+T +L A T G+P M
Sbjct: 2107 WNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQTEC-GRPHREMRM-------- 2157
Query: 1901 LNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIENMN 1960
NPK+IT Q++G D T++WTDGIFS+ R + + DGPVDAIWIEN+N
Sbjct: 2158 -NPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLN 2216
Query: 1961 TVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIE 2020
+VLDDNK L L++G+ I + + ++FEV ++ ASPATVSR GMVY+ S L P ++
Sbjct: 2217 SVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQ 2276
Query: 2021 CWLRKLPPLLKPYEEH--FKALFVSFLEESISFVRSSVKEVIASTNCNLTMSLLKLLDCF 2078
WL+K + +E F L+ E++ ++++ ++ + CN + L LL
Sbjct: 2277 AWLKK-----RTAQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLL--- 2328
Query: 2079 FKPFLPREGLKKIPSEKLSRI--VELIEPWFIFSLIWSVGATGDSSGRTSFSHWLRLKME 2136
EGL IPS++ + VE + F+F L+WS+GA + R +LR
Sbjct: 2329 -------EGL--IPSKEEGGVSCVEHLHKLFVFGLMWSLGALLELESREKLEAFLR---- 2375
Query: 2137 NEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVPDT-- 2194
+ L PE G+N + E W W P+ D+
Sbjct: 2376 QHESKLDLPEIP------------KGSNQTMYEFYVTDYGDWEHWNKKLQPYYYPTDSIP 2423
Query: 2195 NYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDKLLKNLALDYISHFL 2254
Y +I+VP +D ++ + L+D + K VL G GT KT+ + L K +S L
Sbjct: 2424 EYSSILVPNVDNIRTNFLIDTIAKQHKAVLLTGEQGTAKTVMVKAYLKKYDPEVQLSKSL 2483
Query: 2255 TFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLR 2314
FS+ T Q I+S +DKR +GPP GR FIDD+NMP + +G Q E++R
Sbjct: 2484 NFSSATEPMMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVR 2543
Query: 2315 QWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSK 2374
Q M+ G Y G F +VD+ + AM PGGGRN + RL R F + S
Sbjct: 2544 QMMEMEGMYSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASI 2603
Query: 2375 KRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKS 2434
+IF I + D K P I LV +++ ++LPTP+K
Sbjct: 2604 DKIFGIIGCGYFDPCRSFK---------PQICEMIVNLVSVGRVLWQWTKVKMLPTPSKF 2654
Query: 2435 HYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLK 2494
HY FNLRDLS+++QGML + LL L+ HE RV DR + ED WF+ L
Sbjct: 2655 HYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLT 2714
Query: 2495 RCMEQWEVTFNKVCPFQPILYGDFM---------SPGSDV----KSYELITSESKMMQVI 2541
R +E+ + C + DF+ P V K YEL+ S + + +
Sbjct: 2715 RAVEENIGSDAASCILPEPYFVDFLREMPEPTGDEPEDSVFEVPKIYELMPSFDFLAEKL 2774
Query: 2542 EEYIEDYNQI-NTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLAS 2600
+ Y +N+I L LV F DAM+H+ +ISR +R + GNALL+GVGGSG+ SL+RLAS
Sbjct: 2775 QFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALLVGVGGSGKQSLSRLAS 2834
Query: 2601 HMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINNV 2660
+A Y+ FQI L+++Y ++ DD+K + AG ITF+F+D++IK+E+FLE +NN+
Sbjct: 2835 FIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFTDSEIKDEAFLEYLNNL 2894
Query: 2661 LNSGDIPNLYTADEQDQI----VSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCM 2716
L+SG+I NL+ DE D+I +S M+ + PT NL + R R N+H+VLC
Sbjct: 2895 LSSGEISNLFARDEMDEITQGLISVMKRELPRH--PPTFDNLYEYFISRSRKNLHVVLCF 2952
Query: 2717 SPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQ 2776
SP+GE FRAR +FP L++ CT+DWF+ WP EAL +VA+ FL++ + SS+ + Q +++
Sbjct: 2953 SPVGEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQ-VVE 3011
Query: 2777 VCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGL 2836
H VS+ C Y R +VTPKSYL ++ + + +K + RM GL
Sbjct: 3012 TMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGL 3071
Query: 2837 DKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIK-- 2894
DKL+ SE VAK+ +DL A K+ L + IK D +AE T ++ + +IK
Sbjct: 3072 DKLMEASESVAKLSQDL---------AVKEKELAVASIKADEVLAEVTVSAQASAKIKNE 3122
Query: 2895 ANEKAKKAQAIADD-------AQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPG 2947
E KAQ I D+ A+ L+ A PAL+ A A+L + ND+ VR + +PP
Sbjct: 3123 VQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHL 3182
Query: 2948 VKLVIEAVCIM--KGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIG 3005
+ +++ V ++ K I P + EK K W L+ G FL SL +F KD I
Sbjct: 3183 IMRIMDCVLLLFQKKIDPVTMDPEKSCCKPS--WGESLKLMSATG-FLWSLQQFPKDTIN 3239
Query: 3006 DVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQD 3065
+ ++ +QPY + +++ + KV + W AM ++ + + V P + L + +
Sbjct: 3240 EETVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEG 3299
Query: 3066 DLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLING 3125
L V L +A+ L E + + +QAK+ + +K +L + C +++ A LI+G
Sbjct: 3300 RLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDG 3359
Query: 3126 LSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRT-VLYDSWVKQLRSHN 3184
LS EK+RW + + + +N + GD+L+ GF++YLGPF +R +L D W +LR+
Sbjct: 3360 LSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARK 3419
Query: 3185 VPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWI 3244
+P T LI L +P I W + GLP D LS++NG+I + R+ IDPQ+Q WI
Sbjct: 3420 IPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWI 3479
Query: 3245 KNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGN 3304
K+ EK+N L V L+ + F +E+++ G+P L+E++ EELDPAL+ VL K K
Sbjct: 3480 KSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEKNFIKSGTT 3539
Query: 3305 TVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAE 3364
+K+GD + F++YITTKLPNP +TPEI+ K ++I+FT++ GLE+QLL +V+
Sbjct: 3540 FKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILT 3599
Query: 3365 ERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAE 3424
E+ +LE + +L+ ++++K++ED +LY+LS+++G+ VDD LI VL +K AAE
Sbjct: 3600 EKQELEAERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAE 3659
Query: 3425 IQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSG 3484
+ K+ +A +TE I+ + E+ P A R IL+F +++++ V+ MYQ SL FL +F
Sbjct: 3660 VSEKLHVAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQS 3719
Query: 3485 IANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSE 3544
+A SE++ +KRI+NI YLTY +++ R L+E HK +F L+ ++I + G + E
Sbjct: 3720 MARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHRE 3779
Query: 3545 WRYLLSGG-SISIMTENPAP-DWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFD 3602
++ L+ GG ++ + P P W+ D W +++ LS LP F+ + ++ ++ FD
Sbjct: 3780 FQALIKGGAALDLKACPPKPYRWILDMTWLNLVELSKLPQFAEIMNQISRNEKGWKSWFD 3839
Query: 3603 SLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSV 3662
P E +P ++ LD KLL++R D+ + ++A +LE ++ EP NL
Sbjct: 3840 KDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEK 3899
Query: 3663 VFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSSIE 3722
+++S++ TPLI LS G+DP + A+++K + IS+GQGQ A +++ S++
Sbjct: 3900 TWEESDTRTPLICFLSMGSDPTNQIDALAKKLKL--ECRTISMGQGQEVHARKLIQMSMQ 3957
Query: 3723 RGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRD-FRLWLTSLPSNKFPVSILQNGSKM 3781
+G WV QNCHL +M E L+E + + D FR+W+T+ P ++FP+++LQ K
Sbjct: 3958 QGGWVLLQNCHLGLEFM---EELLETLITTEASDDSFRVWITTEPHDRFPITLLQTSLKF 4014
Query: 3782 TIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNI 3841
T EPP+GVRA L ++++ + +D L+ + M +K +L ++ H ERRKFGPLG+NI
Sbjct: 4015 TNEPPQGVRAGLKRTFAGINQDLLDISNLPM-WKPMLYTVAFLHSTVQERRKFGPLGWNI 4073
Query: 3842 PYEFTDGDLRICISQLKMFLDEYD---DIPYKVLKYTAGEINYGGRVTDDWDRRCIMNIL 3898
PYEF D + ++ LDE D + + ++Y GE+ YGGRVTDD+D+R +
Sbjct: 4074 PYEFNSADFSASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFA 4133
Query: 3899 EDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFA 3958
+++ + P + ++IP L Y YI+SLP D PE+FGLH NA+IT+
Sbjct: 4134 RVWFSEKMFEPSFCFYTG---YKIPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQ 4190
Query: 3959 QNETFALLGTIIQLQPKSSSAG-SQGREEIVEDVTQNILLKVPEPINLQWVMAKYPVL-Y 4016
N A+L TI +QPK S G + RE IV +++++L K+P V ++ + +
Sbjct: 4191 SNTASAVLETITNIQPKESGGGVGETREAIVYRLSEDMLSKLPPDYIPHEVKSRLIKMGH 4250
Query: 4017 EESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWS 4076
SMN L QE+ R R++ ++ +L DL A++G ++MS L ++Y+ +P+LW
Sbjct: 4251 LNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWK 4310
Query: 4077 AKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFARKFV 4136
++ S L W +LL+R WI +G P VFW++GFF PQ FLT Q R
Sbjct: 4311 RVSWDS-STLGFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHK 4369
Query: 4137 -ISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEM 4195
++DT++ +V+ + E+T P G YI+GL+++GA WD +L ES PK L+T++
Sbjct: 4370 GWALDTVTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAAWDRRNGKLMESTPKVLFTQL 4429
Query: 4196 AVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKR 4255
V+ + + +D Y+CPIYK R ++ V + T HWI R
Sbjct: 4430 PVLHIFAINSTAPKDPKLYVCPIYKKPRRT--------DLTFITVVYLRTVLSPDHWILR 4481
Query: 4256 GVALIC 4261
GVAL+C
Sbjct: 4482 GVALLC 4487
>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
Length = 4624
Score = 2020 bits (5234), Expect = 0.0
Identities = 1214/3597 (33%), Positives = 1919/3597 (53%), Gaps = 165/3597 (4%)
Query: 731 ATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLAQEVREVVLTHLREK 790
+TI ++ K +I K Y + + +KT+ TQ L E +L +
Sbjct: 1124 STIINSTKKEVITSMDCFKRYNHIWQKGKEEA---IKTFITQSPLLSEFESQILYFQNLE 1180
Query: 791 EILDSSLPSSIIIGPFYINTDNVKQSLSKKRKALATSVLDILAKNLHKEVDSICEEFRSI 850
+ +++ P + +G + T ++K +L+ + KA + K E+++I
Sbjct: 1181 QEINAE-PEYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIFMLIEEF 1239
Query: 851 SRKIYEKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDK 910
++K+ ++++ +K I E + ++ ++ + + Y +++ + ++ ++ +
Sbjct: 1240 NKKLNRPIKDLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKV 1299
Query: 911 WIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEIS 970
K+L + VQ + V + F+K I F + L
Sbjct: 1300 DTLHYAWEKLLARAGEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMASGL 1359
Query: 971 RAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTA 1030
+ E ++ + + Q + + + Y E +F LP T Y +L + K+ ++T
Sbjct: 1360 KPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIYTLY 1419
Query: 1031 SDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEE 1090
+ + S+ + S ++ E++ ++E K + KD A LD++ I++
Sbjct: 1420 NSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAF----LDLKKIIDD 1475
Query: 1091 FKPYIPLIQGLRNPGMRIRHWETLSNQININVRP-KANLTFARCLEMNLQDHIESISKVA 1149
F PL++ + + M RHWE ++ ++ + +E L + E I +
Sbjct: 1476 FSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDIC 1535
Query: 1150 EVAGKEYAIEQALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLL---DDHIVMTQN 1206
A KE IEQ L ++ EW F +K +L+ D S+++ +D +++ +
Sbjct: 1536 ISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRG-DSTSEIIANMEDSLMLLGS 1594
Query: 1207 MSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQLPVESKR 1266
+ + Y PF+ +I W L + +++E W+ Q W+YLE +F DI +QLP E+KR
Sbjct: 1595 LLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGGDIAKQLPKEAKR 1654
Query: 1267 YQTMERIWKKIMKNAYENREVINVC-SDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAF 1325
+ +++ W KIM A+E V+ C D + L L++ QK L+ YLE KR F
Sbjct: 1655 FSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCF 1714
Query: 1326 PRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQEDL--EITHMYSAEGEEVQ 1383
PRF+F+SD LLEIL Q D +Q HL F+NI + F E + I + S EGE ++
Sbjct: 1715 PRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDRILSISSQEGETIE 1774
Query: 1384 LCFSIYPSSNVEDWLREVERSMKASVHDIIEKAIRAYPT--MPRTQWVLNWPGQVTIAGC 1441
L + NVE WL + ++S+H +I +A T+++ ++P QV + G
Sbjct: 1775 LDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLSSFPAQVGLLGI 1834
Query: 1442 QTYWTMEVAEALEAGNLRSQLFPQLCQQ----LSDLVALVRGKLSRMQRAVLSALIVIEV 1497
Q WT + EAL ++ + Q L+ L+ + LS +R LI I V
Sbjct: 1835 QMIWTRDSEEALRNAKFDKKIMQKTNQAFLELLNTLIDVTTRDLSSTERVKYETLITIHV 1894
Query: 1498 HAKDVVSKLIQENVVSVNDFQWISQLRYYWTNND--LYIRAVNAEFIYGYEYLGNSGRLV 1555
H +D+ L ++ S DF+W+ Q R+Y+ + + I + FIY E+LG + RLV
Sbjct: 1895 HQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQNEFLGCTDRLV 1954
Query: 1556 ITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMA 1615
ITPLTDRCY+TL AL + GGAPAGPAGTGKTETTKD+G+ L VVFNCSDQ+DF
Sbjct: 1955 ITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRG 2014
Query: 1616 MGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQRVERFMF-EGVEIPLV 1674
+G+ FKGLA +G+W CFDEFNRID+ VLSV AQQI+ I +++ + F+F +G + +
Sbjct: 2015 LGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMN 2074
Query: 1675 PSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKI 1734
P +F+TMNPGYAGR ELP+NLK FR VAMMVPD +I + L S GF + VLA+K
Sbjct: 2075 PEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKF 2134
Query: 1735 TTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFL 1794
T +KL EQLS Q HYDFG+R + +V+ G KR NP E I +R +RD+N+ K +
Sbjct: 2135 FTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNLSKLI 2194
Query: 1795 QEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVV 1854
ED LF ++ DLFP I + Y L+ AI + L + + K IQL+ET V
Sbjct: 2195 DEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFETQRV 2254
Query: 1855 RHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGE 1914
RHG+M +GP+G+GK+TC L AMT G+P M NPK+IT Q++G
Sbjct: 2255 RHGMMTLGPSGAGKTTCIHTLMRAMTDC-GKPHREMRM---------NPKAITAPQMFGR 2304
Query: 1915 FDLLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSG 1974
D+ T++WTDGIFS+ R W + DGPVDAIWIEN+N+VLDDNK L L++G
Sbjct: 2305 LDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANG 2364
Query: 1975 EIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIECWLRKLPP-----L 2029
+ I + ++FE ++ ASPATVSR GMV++ SIL P +E +L+K P L
Sbjct: 2365 DRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFLKKRSPQEAEIL 2424
Query: 2030 LKPYEEHFKALFVSFLEESISFVRSSVKEVIASTNCNLTMSLLKLLDCFFKPFLPREGLK 2089
+ Y E F L+ F +++ + ++ + + + N+ L+ L +E
Sbjct: 2425 RQLYTESFPDLY-RFCIQNLEYKMEVLEAFVITQSINMLQGLIPL----------KEQGG 2473
Query: 2090 KIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSGRTSFSHWLRLKMENEQLTLLFPEEG- 2148
++ L R+ F+F+L+WS GA + GR WLR + TL P
Sbjct: 2474 EVSQAHLGRL-------FVFALLWSAGAALELDGRRRLELWLRSRPTG---TLELPPPAG 2523
Query: 2149 ---LVFDYRLEDAGISGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVPDTN--YCNIIVPT 2203
FDY + G W W + + DT Y +I+VP
Sbjct: 2524 PGDTAFDYYVAPDG-----------------TWTHWNTRTQEYLYPSDTTPEYGSILVPN 2566
Query: 2204 MDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDKLLKNLALDYISHFLTFSARTSAN 2263
+D V+ L+ + K VL IG GT KT+ I + K ++ L FS+ T+
Sbjct: 2567 VDNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPL 2626
Query: 2264 QTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWY 2323
Q I+S +DKR +GPP G+ FIDD+NMP + +G Q E++RQ M+ G+Y
Sbjct: 2627 MFQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFY 2686
Query: 2324 DRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILG 2383
+ + G F ++VDI F+ AM PGGGRN + RL R F+ + E S +IF
Sbjct: 2687 NLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIF----- 2741
Query: 2384 NWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDL 2443
G++G Y + + + LV T ++ ++LPTPAK HY FNLRDL
Sbjct: 2742 ----GVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDL 2797
Query: 2444 SKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCMEQWEVT 2503
S+V+QGML +++ LL+LW HE RV DR D +WFD+ L +E+
Sbjct: 2798 SRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGE 2857
Query: 2504 FNKVCPFQPI--LYGDFMSPGSDV-------------KSYELITSESKMMQVIEEYIEDY 2548
K+ I + DF+ + K YE I S S + + + +++ Y
Sbjct: 2858 EKKLLVDCGIDTYFVDFLRDAPEAAGETSEEADAETPKIYEPIESFSHLKERLNMFLQLY 2917
Query: 2549 NQ-INTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYEC 2607
N+ I A + +V F DAM H+ +ISR +R GNALL+GVGGSG+ SLTRLAS +A Y
Sbjct: 2918 NESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVS 2977
Query: 2608 FQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIP 2667
FQI L+++Y S +D+K + AG Q ITF+F+D +IK+ESFLE +NNVL+SG++
Sbjct: 2978 FQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVS 3037
Query: 2668 NLYTADEQDQIVSTMRPYIQEQGLQ--PTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRA 2725
NL+ DE D+I S + ++++ + PT NL + RVR N+H+VLC SP+GE FR
Sbjct: 3038 NLFARDEIDEINSDLASVMKKEFPRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRN 3097
Query: 2726 RLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQVCVYIHQSV 2785
R +FP+L++ CTIDWF+ WP +AL +V+ FL +++ S E + ++Q V
Sbjct: 3098 RALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSY-DIDCSLEIKKEVVQCMGSFQDGV 3156
Query: 2786 SKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSED 2845
++KC++Y R +VTPKSYL + + + G+K +E++T NRM +GL+KL SE
Sbjct: 3157 AEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASES 3216
Query: 2846 VAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKAN-EKAK-KAQ 2903
VA + ++LE AK+ L + K D + E T + E++KA +K K +AQ
Sbjct: 3217 VAALSKELE---------AKEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQ 3267
Query: 2904 AIADDAQKD-------LDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVC 2956
AI D KD L+ A PAL+ A A+L+ + +D+ VR + RPP + +++ V
Sbjct: 3268 AIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVL 3327
Query: 2957 IM--KGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQP 3014
++ + + K+ EK T W+ L+ G+FL++L +F KD I + VI+ + P
Sbjct: 3328 LLFQRKVSAVKIDLEKSCTMPS--WQESLKLMT-AGNFLQNLQQFPKDTINEEVIEFLSP 3384
Query: 3015 YIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRIL 3074
Y + ++ T +V +C W +AM + + K V P + L+ ++ + + L
Sbjct: 3385 YFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQENRHLLAMQDL 3444
Query: 3075 DEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQ 3134
+A+ L + + + +QA+Y + +T+K+ L E+C ++ A LI+GL+ EK RW
Sbjct: 3445 QKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLAGEKERWT 3504
Query: 3135 ETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQLRSHNVPHTSEPTLI 3194
E + + GDVL+A F++Y GPF ++R +L + W K++++ +P L
Sbjct: 3505 EQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLNDWRKEMKARKIPFGKNLNLS 3564
Query: 3195 GTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGLD 3254
L + I W + GLPND LS++NG+I + R+ IDPQ+Q WIKN E N L
Sbjct: 3565 EMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESRNELQ 3624
Query: 3255 VFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVI 3314
+ L+ + F +E+++ G+P L+E+VGEELDPAL+ VL + K +K+GD +
Sbjct: 3625 ITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTGSTFKVKVGDKEV 3684
Query: 3315 PYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKN 3374
+ FR+YITTKLPNP YTPEIS + ++I+FT++ GLEDQLLG+V+ E+ +LE+ +
Sbjct: 3685 DVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEKERT 3744
Query: 3375 QLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQ 3434
L+ ++ +K++ED +LYRL+S++G+ V+D LI VL +K A E+ K+ I+ +
Sbjct: 3745 HLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEVTQKLEISAE 3804
Query: 3435 TEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNL 3494
TE I+ R EY PVA R IL+F ++++ V+ MYQ SL FL +F +A S ++
Sbjct: 3805 TEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSLARSVKSPIT 3864
Query: 3495 KKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLLSGG-S 3553
KRI+NI ++TY +Y R L+E+HK +F LL ++I + ++ E+ L+ GG S
Sbjct: 3865 SKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEFLTLIKGGAS 3924
Query: 3554 ISIMTENPAPD-WLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHREPLP 3612
+ + P P W+ D W +++ LS L FS ++ +++ FD P EPLP
Sbjct: 3925 LDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIWFDKENPEEEPLP 3984
Query: 3613 GIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTP 3672
+D+ LD F++LL++R D+ + ++ ++ ++ E +L +++S+ TP
Sbjct: 3985 NAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLEKTWEESDPRTP 4044
Query: 3673 LIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNC 3732
LI +LS G+DP + + +K + +S+GQGQ A +++ ++ G W QNC
Sbjct: 4045 LICLLSMGSDPTDSIIALGKRLKIETRY--VSMGQGQEVHARKLLQQTMANGGWALLQNC 4102
Query: 3733 HLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVRAN 3792
HL +M L +I I + VH FRLW+T+ +FP+++LQ K +PP+G+RA
Sbjct: 4103 HLGLDFMDELMDII--IETELVHDAFRLWMTTEAHKQFPITLLQMSIKFANDPPQGLRAG 4160
Query: 3793 LLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRI 3852
L ++YS + +D L+ ++K +L ++ H ERRKFG LG+NIPYEF D
Sbjct: 4161 LKRTYSGVSQDLLD-VSSGSQWKPMLYAVAFLHSTVQERRKFGALGWNIPYEFNQADFNA 4219
Query: 3853 CISQLKMFLDEYD---DIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSP 3909
+ ++ LD+ D + + ++Y GEI YGGRVTDD+D+R + + +++ ++ P
Sbjct: 4220 TVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFGP 4279
Query: 3910 EHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTI 3969
+ S+ + IP + YL YI+SLP D PE+FGLH NA+IT+ +L TI
Sbjct: 4280 DFSFYQG---YNIPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVLDTI 4336
Query: 3970 IQLQPK-SSSAGSQGREEIVEDVTQNILLKVPE---PINLQWVMAKYPVLYEESMNTVLV 4025
+ +QPK +S G + RE +V + ++L K+P P ++ + K + MN L
Sbjct: 4337 LGIQPKDTSGGGDETREAVVARLADDMLEKLPPDYVPFEVKERLQKMGPF--QPMNIFLR 4394
Query: 4026 QEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKP 4085
QE+ R R+L ++ TL +L A+ G ++MS L +++ +P W ++ S
Sbjct: 4395 QEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDARIPAWWKKASWIS-ST 4453
Query: 4086 LSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFAR-KFVISIDTISF 4144
L W +L++R +W+ +G P FW++GFF PQ FLT Q R ++D +
Sbjct: 4454 LGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVL 4513
Query: 4145 DFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTP 4204
+V +++ P G Y++GL+LEGA WD +L ES+PK L+ M VI +
Sbjct: 4514 CNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIY-AE 4572
Query: 4205 NRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALIC 4261
N +D FY CPIYK R NY+ AV++ T Q HW+ RGVAL+C
Sbjct: 4573 NNTLRDPRFYSCPIYKKPVRT--------DLNYIAAVDLRTAQTPEHWVLRGVALLC 4621
>gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens]
Length = 4486
Score = 2020 bits (5234), Expect = 0.0
Identities = 1180/3313 (35%), Positives = 1837/3313 (55%), Gaps = 164/3313 (4%)
Query: 1002 IFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAF 1061
+F + + +Y +L + KE +LW T +W P I+ E +E +
Sbjct: 1281 LFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFA 1340
Query: 1062 KTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININ 1121
+ + K+ + A + + + + + L+NP +R RHW L ++
Sbjct: 1341 RHIRNLDKEVRAWDAFTGLESTVWNTLSSLRA----VAELQNPAIRERHWRQLMQATGVS 1396
Query: 1122 VRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKA 1181
+ T A L++ L + + + + + A KE +E+ L +++ W+ + F P+
Sbjct: 1397 FTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPR 1456
Query: 1182 TDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQ 1241
T+ +L S ++ ++L+D+ V QN+ S Y F + ++ W+ KL V+ W Q
Sbjct: 1457 TNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQ 1516
Query: 1242 RSWLYLEPIFS-SEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDSL 1300
R+W +LE IF+ SEDI QLP +SKR++ ++ +K++ +A + V+ + + + L
Sbjct: 1517 RTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKL 1576
Query: 1301 RDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENI 1360
D L L +K L+EYL+TKR AFPRFYFLS +LL+ILS P VQ HL K F+N+
Sbjct: 1577 EDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNM 1636
Query: 1361 ARLLFQEDLE------ITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIE 1414
A++ FQ D MYS E E V S VE WL V MKA+V +
Sbjct: 1637 AKMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMT 1696
Query: 1415 KAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEA---LEAG--NLRSQLFPQLCQQ 1469
+ + AY PR QW+ + P QV + Q +WT EV A LE G + + + Q
Sbjct: 1697 EGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQ 1756
Query: 1470 LSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTN 1529
L L+ ++ G+LS+ R + + I+VHA+DVV+K+I + V + F W+SQLR+ W +
Sbjct: 1757 LKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDD 1816
Query: 1530 N--DLYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGK 1587
+ +A+F+Y YEYLGN+ RLVITPLTDRCY+TLT +LHL GAPAGPAGTGK
Sbjct: 1817 EVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGK 1876
Query: 1588 TETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVA 1647
TETTKDLG+AL I VFNCS+Q+D+ + G +KGLA GAW CFDEFNRI +EVLSVVA
Sbjct: 1877 TETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVA 1936
Query: 1648 QQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMM 1707
Q+ +IQ A + + + F F G EI L PS +FITMNPGYAGRTELP+NLK+LFRP AM+
Sbjct: 1937 VQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTELPENLKSLFRPCAMV 1996
Query: 1708 VPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGN 1767
VPD+ +I EI L + GF EA LA+K T ++L E LS QDHYD+G+RA+K+V+ AG+
Sbjct: 1997 VPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGS 2056
Query: 1768 LKRENPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTI---KEEDTDYGILDE 1824
LKR +P E+ + +R++RD N+PK + +D+ +F G++ DLFP + + D ++ L
Sbjct: 2057 LKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEAL-- 2114
Query: 1825 AIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKG 1884
+R+A + L+ + F+ K +QL E VRH + +VG G+GKS R L +K
Sbjct: 2115 -VRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKR 2173
Query: 1885 QPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKW 1944
+P + LNPK++T +L+G + T EW DG+FSS +R A + KW
Sbjct: 2174 RPV----------WTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDGPKW 2223
Query: 1945 YMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCG 2004
+ DG +D +WIE++NTV+DDNK L L+S E I L M ++FE+ L A+PATVSR G
Sbjct: 2224 ILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVSRAG 2283
Query: 2005 MVYLEPSILGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEESISFVRSSVKEVIASTN 2064
++Y+ P+ LG P + W+ K ++ + LF +L + +R+ K++I
Sbjct: 2284 ILYINPADLGWNPPVSSWIEKRE--IQTERANLTILFDKYLPTCLDTLRTRFKKIIPIPE 2341
Query: 2065 CNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSG- 2123
++ + LL+C + IP++ E+ E +F+F+ IW+ G
Sbjct: 2342 QSMVQMVCHLLECLLT-------TEDIPADCPK---EIYEHYFVFAAIWAFGGAMVQDQL 2391
Query: 2124 ---RTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVK 2180
R FS W + + T+ FP +G +FDY + D E ++ E
Sbjct: 2392 VDYRAEFSKWWLTEFK----TVKFPSQGTIFDYYI---------DPETKKFE-------P 2431
Query: 2181 WMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDK 2240
W F P+ +V T +T+++ + ++ L+ ++PV+ +G GTGK++ + K
Sbjct: 2432 WSKLVPQFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVLVGAK 2491
Query: 2241 LLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPA 2300
L Y+ + F+ T++ Q ++ L+K+ +GPP + I+FIDD+NMP
Sbjct: 2492 LASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFIDDMNMPE 2551
Query: 2301 LETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRH 2360
++ YG P ++RQ +D+G WYDR + + K + ++ +V M P G T+ PRL RH
Sbjct: 2552 VDAYGTVQPHTIIRQHLDYGHWYDRSKL-SLKEITNVQYVSCMNPTAGS-FTINPRLQRH 2609
Query: 2361 FN--YLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIM 2418
F+ LSF D +S I+S IL L S ++ +P PL++ +
Sbjct: 2610 FSVFVLSFPGADALSS--IYSIILTQHLKLGNFPASLQKSIP----------PLIDLALA 2657
Query: 2419 VYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRD 2478
+ I + LPT K HY FNLRD + +FQG+L + V+ L+RL+ HE+ RV+RD
Sbjct: 2658 FHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRD 2717
Query: 2479 RLVNEEDRSWFD----QLLKRCMEQWEVTFNKVCPFQPILYGDFMSPGSDVKSYELITSE 2534
++V E+D FD ++LK+ + E + P LY F + G Y + S
Sbjct: 2718 KMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQT--QSPNLYCHFAN-GIGEPKYMPVQSW 2774
Query: 2535 SKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSS 2594
+ Q + E +E++N++NT + LVLF DAM H+C I+R L GNALL+GVGGSG+ S
Sbjct: 2775 ELLTQTLVEALENHNEVNTV-MDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQS 2833
Query: 2595 LTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFL 2654
LTRLA+ ++ + FQI L K Y + +++ D+ + LKAG++NL FL +D Q+ +E FL
Sbjct: 2834 LTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADERFL 2893
Query: 2655 EDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVL 2714
IN++L SG+IP+LY+ DE + I+S +R ++ QGL + N + R+R + + L
Sbjct: 2894 VLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENCWKFFIDRIRRQLKVTL 2953
Query: 2715 CMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGL 2774
C SP+G R R R+FP++VNC I WF+EWP +AL+SV+ FL +E + + Q +
Sbjct: 2954 CFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVK--QSI 3011
Query: 2775 IQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKS 2834
+ ++H SV++ YL+ R+NY TPKS+LE + ++ L+ + + ELK R+++
Sbjct: 3012 SKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLEN 3071
Query: 2835 GLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDT-------AIAEETRNS 2887
GL KL TS V ++ L + L++ +D ++ + V+T A+A+E
Sbjct: 3072 GLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQK 3131
Query: 2888 VQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPG 2947
V ++ +K K D ++DL +A PAL AA A+L LNK ++TE+++ PP
Sbjct: 3132 VAVIMLEVKQKQK-------DCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLA 3184
Query: 2948 VKLVIEAVCIM---KGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNI 3004
V V AV ++ +G PK D W+ K + FL+SL F+K+NI
Sbjct: 3185 VSNVSAAVMVLMAPRGRVPK-----------DRSWKAAKVTMAKVDGFLDSLINFNKENI 3233
Query: 3005 GDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQ 3064
+ +KAI+PY+ + EF P +A S A +C WV + +++ V VEPKRQAL +A
Sbjct: 3234 HENCLKAIRPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKAT 3293
Query: 3065 DDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLIN 3124
DL Q L K ++ + + +A + A++ + K + + + E + A +L+
Sbjct: 3294 ADLTAAQEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVG 3353
Query: 3125 GLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYD-SWVKQLRSH 3183
GL+ E VRW + V+N + + GD+L+ F++YLG FT +YR L D +W L
Sbjct: 3354 GLASENVRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQL 3413
Query: 3184 NVPHTSEPTL--IGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQAN 3241
P P L + L + + +WQ GLP D +SVEN I +RW +DPQ Q
Sbjct: 3414 KTPIPVTPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGI 3473
Query: 3242 KWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQ 3301
KWIKN ++ L V ++ + +L+ +E A+ G L+EN+ E +DP L P+L ++ K+
Sbjct: 3474 KWIKNKYGED-LRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKK 3532
Query: 3302 QGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQV 3361
+K+GD Y+ FR+ + TKL NPHY PE+ + TLINFT++ GLEDQLL V
Sbjct: 3533 --GRFIKIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAV 3590
Query: 3362 VAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMK 3421
V+ ERPDLE+ K+ L + LK +ED +L RLSS+ GN + + L++ LE +K
Sbjct: 3591 VSMERPDLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQT 3650
Query: 3422 AAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIF 3481
AAE++ KV+ A+ TE I+ R Y P A R +L+F ++DL+ + PMYQ+SL+ F +F
Sbjct: 3651 AAEVEKKVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVF 3710
Query: 3482 LSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKIN 3541
+ + ++L++R++N+ +T+S+Y R LFE KL + L +I++ ++N
Sbjct: 3711 QKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVN 3770
Query: 3542 QSEWRYLLSGGSISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIF 3601
E +LL + T +P ++LS +AW + LS++ FS+ D ++
Sbjct: 3771 AVELDFLLR-SPVQTGTASPV-EFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFV 3828
Query: 3602 DSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLS 3661
+S P +E LP W + Q+L +LR +R D++T A++DFV L +++ + + +
Sbjct: 3829 ESECPEKEKLPQEW-KNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFA 3887
Query: 3662 VVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKF---SKKLSAISLGQGQGPRAEAMMR 3718
F++S TP+ F+LSPG DP D+ ++ + ++ +SLGQGQ AEA +
Sbjct: 3888 TSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALD 3947
Query: 3719 SSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPS-----NKFPVS 3773
+ ++G WV QN HL W+ LE+ +E + + H +FR+++++ P+ + P
Sbjct: 3948 LAAKKGHWVILQNIHLVAKWLSTLEKKLEE-HSENSHPEFRVFMSAEPAPSPEGHIIPQG 4006
Query: 3774 ILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRK 3833
IL+N K+T EPP G+ ANL K+ + +D L C + EFKS+L +LC FH ERRK
Sbjct: 4007 ILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRK 4066
Query: 3834 FGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRC 3893
FGP G+N Y F GDL I ++ L FL+ +PY L+Y GEI YGG +TDDWDRR
Sbjct: 4067 FGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRL 4126
Query: 3894 IMNILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNA 3953
L +F P++L E S + +P D +GY YI + + P ++GLH NA
Sbjct: 4127 CRTYLGEFIRPEMLEGELSLAPG---FPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNA 4183
Query: 3954 NITFAQNETFALLGTIIQLQPKSSSA---GSQGREEIVEDVTQNILLKVPEPINLQWVMA 4010
I F + L T+++LQP+ S A REE V+ + + IL +V + N+ +MA
Sbjct: 4184 EIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMA 4243
Query: 4011 KYPVLYEESMNTVLV--QEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYN 4068
K EE ++V QE R N L + I ++L++L LKG + M+S +E + +LY
Sbjct: 4244 K----VEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYF 4299
Query: 4069 NTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQD-GIPAVFWISGFFFPQAFLTGT 4127
+ VPE W+ +AYPS L++W DLL R+ L+AW D +P+ W++GFF PQ+FLT
Sbjct: 4300 DMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAI 4359
Query: 4128 LQNFARKFVISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQ 4187
+Q+ ARK +D ++ + + E P+ G YIHGLF+EGA WD +A + E++
Sbjct: 4360 MQSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAK 4419
Query: 4188 PKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQ 4247
K+L M V+++ P K + Y CP+YKT R T YV + T +
Sbjct: 4420 LKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRGPT---------YVWTFNLKTKE 4470
Query: 4248 PQRHWIKRGVALI 4260
W+ GVAL+
Sbjct: 4471 NPSKWVLAGVALL 4483
>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4470
Score = 2019 bits (5231), Expect = 0.0
Identities = 1250/3734 (33%), Positives = 1994/3734 (53%), Gaps = 238/3734 (6%)
Query: 619 LASFSQFISDTCCSVLNCTDDMVWGDDLINSPYRPRKNPLFIMDLVLDSSGVHYSTPLEQ 678
L F QFI + ++ D+MV + + PLF + + LD G+ ++ LE
Sbjct: 880 LDEFDQFIRKSLSFLM---DNMVIDESIA---------PLFEIRMELDEDGLTFNPTLEV 927
Query: 679 FEASLLNLFDKGILATHAVPQLEKLVMEDIF--------ISGDPLLESVGLHEPL-VEEL 729
D+G LA +E LV DI+ ++ D + + L + + E+
Sbjct: 928 GS-------DRGFLAL-----IEGLV-NDIYNVARLIPRLAKDRMNYKMDLEDNTDLIEM 974
Query: 730 RATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTY-------------------- 769
R ++S V AM + Y + +Y L +++ F+K +
Sbjct: 975 REEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTI 1034
Query: 770 -QTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKKRKALATSV 828
+T LAQ +E + ++ + E + + + G + KQ+L +
Sbjct: 1035 PKTPPTLAQ-FQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMF 1093
Query: 829 LDILAKNLHKEVDSICEEFRSISRKIYEKP---NSIEELAELREWMKGIPERLVGLE--- 882
L+ ++ + + E F ++R KP + L E+ + + ER +
Sbjct: 1094 KRHLSNHVTNSLADL-EAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATDNMF 1152
Query: 883 ---ERIVKVMDDY-QVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKF 938
++ ++++ Y + M E ++ L + + W + K+ Q++L +E
Sbjct: 1153 EPLKQTIELLKTYGEEMPEEIH-LKLQELPEHWANTK---KLAIQVKLTVAPLQANEVSI 1208
Query: 939 --RKIQIMD--QNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQLAM 994
RK Q + Q+ F+E+ E + N + + KQ K +
Sbjct: 1209 LRRKCQQFELKQHEFRERFRR------------EAPFSFSDPNPYKSLNKQQKSISAMEG 1256
Query: 995 LYNNRER---IFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAE 1051
+ + +F +P+ +Y +L +E + +LW E W I+ E
Sbjct: 1257 IMEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVE 1316
Query: 1052 QLEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHW 1111
Q++ + + K M K+ K A V LD ++ + + L+NP +R RHW
Sbjct: 1317 QMDIDCKKFAKDMRSLDKEMKTWDAF--VGLD--NTVKNVITSLRAVSELQNPAIRERHW 1372
Query: 1112 ETLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWST 1171
+ L + + T A L++NL + + + + + A KE +E+ L ++ WS
Sbjct: 1373 QQLMQATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSM 1432
Query: 1172 ILFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQ 1231
+ F P+ T T +LKS + + L+D+ V QN+ S Y F + + SW+ KL
Sbjct: 1433 MEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTAD 1492
Query: 1232 EVLEEWLNCQRSWLYLEPIF-SSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINV 1290
V+ W QR+W +LE IF SEDI QLP +S+R+ + + +K +M++A + V+
Sbjct: 1493 SVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEA 1552
Query: 1291 CSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQ 1350
S + + L K L + +K L+EYLETKR AFPRFYF+S +LL+ILS DP V
Sbjct: 1553 TSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVS 1612
Query: 1351 PHLRKCFENIARLLFQED-----LEI-THMYSAEGEEVQLCFSIYPSSNVEDWLREVERS 1404
HL K F+++ +L F+ D L++ MYS E E + S VE WL V
Sbjct: 1613 RHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDR 1672
Query: 1405 MKASVHDIIEKAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEA---LEAG--NLR 1459
M +++ I +A+ Y PR QW+L++P QV + Q +WT EV A LE G N
Sbjct: 1673 MCSTLRHEIPEAVVTYEEKPREQWILDYPAQVALTCTQIWWTTEVGLAFARLEEGYENAI 1732
Query: 1460 SQLFPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQW 1519
+ QL+ L+ L+ G L+ R + + I+VHA+DVV+K+I V S F W
Sbjct: 1733 RDYNKKQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAKVESSQAFTW 1792
Query: 1520 ISQLRYYWTNNDLYIRA--VNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGG 1577
+QLR+ W + A +A+ Y YEYLGN+ RLVITPLTDRCY+TLT +LHL GG
Sbjct: 1793 QAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGG 1852
Query: 1578 APAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNR 1637
APAGPAGTGKTETTKDLG+AL VFNCS+Q+D+ + G +KGLA GAW CFDEFNR
Sbjct: 1853 APAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNR 1912
Query: 1638 IDIEVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNL 1697
I +EVLSV+A Q+ +Q A + + + F F G I L+P+ +FITMNPGYAGR ELP+NL
Sbjct: 1913 ISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENL 1972
Query: 1698 KALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRA 1757
KALFRP AM+VPD+ +I EI L + GF EA +LA+K T + L E LS QDHYD+G+RA
Sbjct: 1973 KALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRA 2032
Query: 1758 VKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTI---KE 1814
+K+V+ AG+LKR +PS E+ + +RA+RD N+PK + +DL +F G++ DLFP + ++
Sbjct: 2033 IKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRK 2092
Query: 1815 EDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRV 1874
D ++ ++ I+++ L+ + F+ K +QL E VRH + +VG GSGKS +
Sbjct: 2093 RDLNF---EKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKS 2149
Query: 1875 LAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAG 1934
L +LK +P AV+ L+PK++T +L+G + +T EW DG+FS+ +R
Sbjct: 2150 LNKTYQNLKRKP-------VAVD---LDPKAVTCDELFGIINPVTREWKDGLFSTIMRDL 2199
Query: 1935 AITSDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAV 1994
A + KW + DG +D +WIE++NTV+DDNK L L+S E I L M ++FE+ L
Sbjct: 2200 ANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRT 2259
Query: 1995 ASPATVSRCGMVYLEPSILGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEESISFVRS 2054
A+PATVSR G++Y+ P+ LG P + W+ + ++ + + LF +L + +R
Sbjct: 2260 ATPATVSRAGILYINPADLGWNPVVSSWIERRK--VQSEKANLMILFDKYLPTCLDKLRF 2317
Query: 2055 SVKEVIASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWS 2114
K++ + ++L LL+C K +P + EL E +F+F+ W+
Sbjct: 2318 GFKKITPVPEITVIQTILYLLECLLTE-------KTVPPDSPR---ELYELYFVFTCFWA 2367
Query: 2115 VGATGDSSG----RTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEE 2170
G R FS W NE T+ FP +G +FDY ++ D++
Sbjct: 2368 FGGAMFQDQLVDYRVEFSKW----WINEFKTIKFPSQGTIFDYYIDP-------DTK--- 2413
Query: 2171 EEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTG 2230
++ W D F + PD +V T +T+++ + +D+L+ PV+ +G G
Sbjct: 2414 ------KFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAG 2467
Query: 2231 TGKTLTISDKLLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFI 2290
TGK++ + DKL +Y+ + F+ T++ Q ++ L+K+ +GPP + +
Sbjct: 2468 TGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLV 2527
Query: 2291 FFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGR 2350
+FIDD+NMP ++ YG P L+RQ MDH WYDR + K++ + +V M P G
Sbjct: 2528 YFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKL-TLKDIHNCQYVACMNPTSGS- 2585
Query: 2351 NTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTE 2410
T+ RL RHF + + + + I++TIL L ++R + I +
Sbjct: 2586 FTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHL-------AFRS---VSMAIQRISS 2635
Query: 2411 PLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYH 2470
LV A + ++ IT+ LPT K HY FNLRDLS +FQG+L + ++ + L+RLW H
Sbjct: 2636 QLVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLH 2695
Query: 2471 ENCRVFRDRLVNEEDRSWFDQLLKRCMEQWEVTFNKVCPF-QPILYGDFMSPGSDVKSYE 2529
E RV+ D++V+E+D+ ++ +++ F +P ++ F D K Y
Sbjct: 2696 ETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPK-YV 2754
Query: 2530 LITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGG 2589
+T + + +++ + ++ YN++N A + LVLF DA++HICRI+R L GNALL+GVGG
Sbjct: 2755 PVTDMAPLNKLLVDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILESPRGNALLVGVGG 2813
Query: 2590 SGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIK 2649
SG+ SL+RLA++++ + FQI L K YG+ + + D+ +KA ++N+P FL +D+Q+
Sbjct: 2814 SGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVA 2873
Query: 2650 NESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSN 2709
E FL IN++L SG+IP L+ DE + I+S+MRP ++ G+ T+ + +VR
Sbjct: 2874 EEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQ 2933
Query: 2710 IHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQE 2769
+ ++LC SP+G V R R R+FP++VNC IDWF+EWP +AL SV+ FL E + +
Sbjct: 2934 LKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPVIKA 2993
Query: 2770 EIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAK 2829
I + Y+H +V++ YLA R+NY TPK++LE + ++ L+ +K+ EL
Sbjct: 2994 SISFFMS---YVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKI 3050
Query: 2830 NRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQ 2889
R+++GL KL T+ V ++ L L++ + ++ + ++ + +
Sbjct: 3051 ERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIAD 3110
Query: 2890 TEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVK 2949
EE+K K + DL +A PAL AA +L LNKN++TE+++ PP V
Sbjct: 3111 QEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVV 3170
Query: 2950 LVIEAVCIMKGIKPKKVPGEKPGTKV--DDYWEPGKGLLQDPGHFLESLFKFDKDNIGDV 3007
V AV I+ PG K+ D W+ K ++ FL+SL KFDK++I +
Sbjct: 3171 NVTAAVMILTA----------PGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEA 3220
Query: 3008 VIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDL 3067
+KA +PY N F P I S A +C W + +++ V V PKRQAL EA +L
Sbjct: 3221 CLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAEL 3280
Query: 3068 GVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLS 3127
Q L K ++ E+ ++ + + + + +K + + + + + + A +L+ GL+
Sbjct: 3281 AEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLA 3340
Query: 3128 DEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDS-WVKQLRSHN-- 3184
E +RW E+VEN + + GDVL+ + FV+Y+G FT +YR L + W+ + HN
Sbjct: 3341 SENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYI--HNLK 3398
Query: 3185 --VPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANK 3242
+P T+ + L + + +W GLP+D +S EN I ++RW +D Q Q K
Sbjct: 3399 VPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIK 3458
Query: 3243 WIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQ 3302
WIKN + L +L + +L +E AI G L+EN+GE +DP L+P+L + T K+
Sbjct: 3459 WIKNKYRSE-LKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKK- 3516
Query: 3303 GNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVV 3362
+K+GD + YH FR+ + TK NPHY PE+ + TLINF ++ GLEDQLL VV
Sbjct: 3517 -GKYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVV 3575
Query: 3363 AEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKA 3422
A+ERPDLE+ K L S + + LK++ED +L RLS++ GN + D L++ LE +K A
Sbjct: 3576 AKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTA 3635
Query: 3423 AEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFL 3482
+EI+ KV A+ TE I+ R Y P A R +L+F ++DL ++P+YQ+SL+ F +F
Sbjct: 3636 SEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFE 3695
Query: 3483 SGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQ 3542
I + A+ +K+R+ N+ +TYS+Y R LFE+ KL+F + +++ + ++N
Sbjct: 3696 KAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNP 3755
Query: 3543 SEWRYLL----SGGSISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFR 3598
E +LL G +S + D+L + W I ALS + F + SD ++
Sbjct: 3756 VELDFLLRFPFKAGVVSPV------DFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWK 3809
Query: 3599 VIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTA 3658
+ +S P +E P W + QKL ++RCLR D++T A+++FV + +F+E ++
Sbjct: 3810 KLVESEAPEKEIFPKEW-KNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSV 3868
Query: 3659 NLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKF---SKKLSAISLGQGQGPRAEA 3715
S +++S+ +T + F+LSPG DP D+ +++ F + KL +SLGQGQ AE
Sbjct: 3869 EFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAEN 3928
Query: 3716 MMRSSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLP-----SNKF 3770
+ + E+G WV QN HL W+ L++ +E + H D+R+++++ P ++
Sbjct: 3929 ALDVAAEKGHWVILQNIHLVARWLGTLDKKLERYSTGS-HEDYRVFISAEPAPSPETHII 3987
Query: 3771 PVSILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALE 3830
P IL+N K+T EPP G+ ANL K+ +D L C K MEFK +L +LC FH E
Sbjct: 3988 PQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAE 4047
Query: 3831 RRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWD 3890
RRKFG G+N Y F +GDL I I+ L +L+ +P+ L+Y GEI YGG +TDDWD
Sbjct: 4048 RRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWD 4107
Query: 3891 RRCIMNILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLH 3950
RR L ++ ++L + + QIPP D GY YI + P ++GLH
Sbjct: 4108 RRLCRTYLAEYIRTEMLEGDVLLAPG---FQIPPNLDYKGYHEYIDENLPPESPYLYGLH 4164
Query: 3951 DNANITFAQNETFALLGTIIQLQPKSSSAGS---QGREEIVEDVTQNILLKVPEPINLQW 4007
NA I F + L T++++QPK + +G+ REE V+ V +IL K+PE N+
Sbjct: 4165 PNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKIPETFNMAE 4224
Query: 4008 VMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLY 4067
+MAK + V QE R N L + ++L++L LKG + +++ +E ++ +L+
Sbjct: 4225 IMAK--AAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALF 4282
Query: 4068 NNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQD-GIPAVFWISGFFFPQAFLTG 4126
+TVP+ W A+AYPS+ L++W DLL R+ L+AW D +P W++GFF PQ+FLT
Sbjct: 4283 YDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTA 4342
Query: 4127 TLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAES 4186
+Q+ ARK +D + +V + ++T P+ G Y++GLF+EGARWD + +AE+
Sbjct: 4343 IMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEA 4402
Query: 4187 QPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTH 4246
+ KEL M VI++ P + + ++ Y CP+YKT R T YV + T
Sbjct: 4403 RLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPT---------YVWTFNLKTK 4453
Query: 4247 QPQRHWIKRGVALI 4260
+ WI VAL+
Sbjct: 4454 EKAAKWILAAVALL 4467
>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
Length = 4523
Score = 2000 bits (5182), Expect = 0.0
Identities = 1198/3462 (34%), Positives = 1887/3462 (54%), Gaps = 182/3462 (5%)
Query: 864 LAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASNWPSKILGQ 923
L +R + E L+E I + Q M E +Y + ++ ++W + KI
Sbjct: 1176 LLAVRSRQRATDELFEPLKETITLLESYGQKMPEQVY-IQLEELPERWETTK---KIAAT 1231
Query: 924 IEL-VQQQHVEDEEKFRKIQIM---DQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEV 979
+ V H + RK I+ Q F+E+ GF+ + + E+
Sbjct: 1232 VRHEVSPLHNAEVTLIRKKCILFDAKQAEFRERFR--HYAPLGFNAENPYTALDKANEEL 1289
Query: 980 RRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSES 1039
+++++ Q+ R+F + + Y ++ + KE + LW R ++
Sbjct: 1290 EALEEEMLQMQEST-------RLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDN 1342
Query: 1040 WMNDPLSAIDAEQLEKNVVEAFK--------TMHKCVKQFKDMPACQEVALDIRARIEEF 1091
W I EQ++ + K +++K V+ + + D+ A +
Sbjct: 1343 WTKTQWRQIHVEQMDVELRRFAKASSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRA- 1401
Query: 1092 KPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEV 1151
I L++P +R RHW L I + T A L + L + + ++ +
Sbjct: 1402 ------ITELQSPALRDRHWHQLMKAIGVKFLINEATTLADLLALRLHRVEDDVRRIVDK 1455
Query: 1152 AGKEYAIEQALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSP 1211
A KE E+ + ++ + W+T+ F+ + T +LKS ++ + L+ + V Q + S
Sbjct: 1456 AVKELGTEKVITEISQTWATMKFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSK 1515
Query: 1212 YKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIF-SSEDINQQLPVESKRYQTM 1270
Y + F +++ SW+NKL + V+ W+ QR+W +LE IF SEDI QL +++R+ +
Sbjct: 1516 YVEYFIEQVLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGV 1575
Query: 1271 ERIWKKIMKNAYENREVINVCSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYF 1330
+ +K++M + V+ + + L+D L L +K L+EYLETKR AFPRFYF
Sbjct: 1576 DAEFKELMFKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYF 1635
Query: 1331 LSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQEDLEITH-----MYSAEGEEVQLC 1385
+S +LL+ILS+ P V HL K F++IA L F+++ +++ MYS E E V
Sbjct: 1636 VSSADLLDILSKGAQPKQVTCHLAKLFDSIADLQFEDNQDVSAHRAVGMYSKEKEYVPFQ 1695
Query: 1386 FSIYPSSNVEDWLREVERSMKASVHDIIEKAIRAYPTMPRTQWVLNWPGQVTIAGCQTYW 1445
+VE WL ++E++M+ +V I +AI AY PR W+ ++P QV + Q +W
Sbjct: 1696 AECECVGHVETWLLQLEQTMQETVRHSITEAIVAYEEKPRELWIFDFPAQVALTSSQIWW 1755
Query: 1446 TMEVAEA---LEAG--NLRSQLFPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIEVHAK 1500
T +V A LE G + QL+ L+ L+ G+L R + + I+VHA+
Sbjct: 1756 TTDVGIAFSRLEEGYETALKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDVHAR 1815
Query: 1501 DVVSKLIQEN--VVSVNDFQWISQLRYYW--TNNDLYIRAVNAEFIYGYEYLGNSGRLVI 1556
DVV+KLI + VVS F W+SQLR+ W T ++ +A+F Y YEYLGNS RLVI
Sbjct: 1816 DVVAKLISQKQVVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPRLVI 1875
Query: 1557 TPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAM 1616
TPLTDRCY+TLT +LHL GAPAGPAGTGKTETTKDLG+AL + VFNCS+Q+D+ ++
Sbjct: 1876 TPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSI 1935
Query: 1617 GKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLVPS 1676
G +KGL GAW CFDEFNRI +EVLSVVA Q+ I A + R +RF+F G I L PS
Sbjct: 1936 GNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITLKPS 1995
Query: 1677 CAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITT 1736
+FITMNPGYAGRTELP+NLKALFRP AM+ PD +I EI L + GF +A LA+K T
Sbjct: 1996 VGIFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARALARKFIT 2055
Query: 1737 TFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQE 1796
+ L E LS QDHYD+G+RA+K+V+ AG+LKR + + E+ + +RA+RD N+PK + +
Sbjct: 2056 LYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTD 2115
Query: 1797 DLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVRH 1856
D+ +F G+V DLFP + ++ +R++ L+ E F+ K +QL E VRH
Sbjct: 2116 DIPVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEELLAVRH 2175
Query: 1857 GLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFD 1916
+ +VG G+GKS R L ++K +P + LNPK++T +L+G
Sbjct: 2176 SVFVVGNAGTGKSKILRTLNRTYVNMKQKPV----------WNDLNPKAVTTDELFGFIH 2225
Query: 1917 LLTHEWTD---------GIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIENMNTVLDDNK 1967
T EW D G+FSS +R A KW + DG +D +WIE++NTV+DDNK
Sbjct: 2226 HATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTVMDDNK 2285
Query: 1968 KLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIECWLRKLP 2027
L L+S E I LT M ++FE+ L A+PATVSR G++Y+ P LG P++ W+ +
Sbjct: 2286 VLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASWIDRRR 2345
Query: 2028 PLLKPYEEHFKALFVSFLEESISFVRSSVKEVIASTNCNLTMSLLKLLDCFFKPFLPREG 2087
+ + + LF ++ + +R+S K + + +L +L LL+C P
Sbjct: 2346 H--QSEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQTLCVLLECLLTP------ 2397
Query: 2088 LKKIPSEKLSRIVELIEPWFIFSLIWSVGAT----GDSSGRTSFSHWLRLKMENEQLTLL 2143
+ +PS+ E+ E +F+F+ IW+ G T S + FS W + E +
Sbjct: 2398 -ENVPSDSPK---EVYEVYFVFACIWAFGGTLLQDQISDYQADFSRW----WQKEMKAVK 2449
Query: 2144 FPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPT 2203
FP +G +FDY + ++K + W D A FTM PD ++V T
Sbjct: 2450 FPSQGTIFDYYV----------------DHKTKKLLPWADKIAQFTMDPDVPLQTVLVHT 2493
Query: 2204 MDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDKLLKNLALDYISHFLTFSARTSAN 2263
+T ++ + +++LL KP++ +G G GKT+ + D L +L+ DYI + F+ T++
Sbjct: 2494 TETARLRYFMELLLEKGKPLMLVGNAGVGKTVFVGD-TLASLSEDYIVSRVPFNYYTTST 2552
Query: 2264 QTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWY 2323
Q ++ L+K+ +GP + I+FIDD+NMP ++ YG P L+RQ +D+G WY
Sbjct: 2553 ALQKILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWY 2612
Query: 2324 DRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILG 2383
DR+ + K + + +V M P G T+ PRL RHF +F +TI G
Sbjct: 2613 DRQKV-MLKEIHNCQYVACMNPMVGS-FTINPRLQRHFTVFAF----NFPSLDALNTIYG 2666
Query: 2384 NWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDL 2443
++++ AP I L++ATI + T+ LPT K HY FNLRDL
Sbjct: 2667 QIFSFHFQQQAF------APSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDL 2720
Query: 2444 SKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFD-QLLKRCMEQWEV 2502
S VFQG+L A P ++ + L+ LW HE+ RV+ D+L++++D F ++L+ + +E
Sbjct: 2721 SNVFQGILFASPECLKGPLDLIHLWLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFEG 2780
Query: 2503 TFNKVCPFQPILYGDFMSPGSD-----VKSYELITSESKMMQVIEEYIEDYNQINTAKLK 2557
+ + QP++Y F G D VK +E++ + ++ E +++YN++N A +
Sbjct: 2781 IDSHMLLQQPLIYCHFADRGKDPHYMPVKDWEVLKT------ILTETLDNYNELNAA-MH 2833
Query: 2558 LVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYG 2617
LVLF DAM H+CRISR LR G ALL+GVGGSG+ SL+RLA+++ E FQI L++ YG
Sbjct: 2834 LVLFEDAMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYG 2893
Query: 2618 MSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQ 2677
+ E R D+ + ++ G +N+P FL +D Q+ +ESFL IN++L SG+IP+L++ ++ D+
Sbjct: 2894 IQELRVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDK 2953
Query: 2678 IVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCC 2737
I+S + + G+ ++ N + RVR + ++LC SP+G R R R+FP++VNC
Sbjct: 2954 IISGIHNEVHALGMVDSRENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCT 3013
Query: 2738 TIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELT 2797
IDWF+ WP EAL SV+ F+ E +E ++ L ++H +V++ Y
Sbjct: 3014 AIDWFHAWPQEALVSVSRRFIEETKGIEPVHKDSISLFM--AHVHTTVNEMSTRYYQNER 3071
Query: 2798 RHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMH 2857
RHNY TPKS+LE + +F L+ +K+ E+ K R+ +G+ KL T+ V ++ L S
Sbjct: 3072 RHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQE 3131
Query: 2858 PLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEAL 2917
L+ D + +I + T + EE K + + + DL +A
Sbjct: 3132 AELQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAE 3191
Query: 2918 PALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIM---KGIKPKKVPGEKPGTK 2974
PAL AA A+L LN+ +++E++A PP V V AV ++ +G PK
Sbjct: 3192 PALVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVPK---------- 3241
Query: 2975 VDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAI-QPYIDNEEFQPATIAKVSKAC 3033
D W+ K + FL++L +DK++I + +K + + Y+ + EF P I S A
Sbjct: 3242 -DRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAA 3300
Query: 3034 TSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQA 3093
+C WV + K++ V VEPKRQAL +A +L L+ +++L +++ ++ + A
Sbjct: 3301 AGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTA 3360
Query: 3094 KYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVLV 3153
+ + +K + + Q + + A +L+ L +K+RW +++++ + + GDVL+
Sbjct: 3361 SFEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLL 3420
Query: 3154 AAGFVAYLGPFTGQYR-TVLYDSWVKQLRSH-NVPHTSEPTLIGTLGNPVKIRSWQIAGL 3211
A FV+Y+GPFT QYR +++ WV L+ ++P T LI L + I +W GL
Sbjct: 3421 TAAFVSYVGPFTRQYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGL 3480
Query: 3212 PNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGLDVFKLSDRDFLRSMENAI 3271
P+D +S EN I +RW IDPQ Q KWIKN + L V L + FL ++E A+
Sbjct: 3481 PSDRMSTENAAILTHCERWPLVIDPQQQGIKWIKN-KYGMDLKVTHLGQKGFLNAIETAL 3539
Query: 3272 RFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPNP 3331
FG L+EN+ E +DP L+P+L + T K+ +++GD ++++FR+ + TKL NP
Sbjct: 3540 AFGDVILIENLEETIDPVLDPLLGRNTIKK--GKYIRIGDKECEFNKNFRLILHTKLANP 3597
Query: 3332 HYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLIISNAKMRQELKDIE 3391
HY PE+ + TL+NFT++ GLE QLL +VV+ ERPDLE+ K L + ELK +E
Sbjct: 3598 HYKPELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLE 3657
Query: 3392 DQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAI 3451
D +L RLS++EG+ +DD +L++ LEA+K AEI+ KV A++ E+ I+ R Y PVA
Sbjct: 3658 DDLLLRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAA 3717
Query: 3452 RTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLKKRISNINRYLTYSLYS 3511
R +L+F ++DL ++P+YQ+SL+ F +F I +++ ++++ RIS + +T++++
Sbjct: 3718 RASLLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFL 3777
Query: 3512 NVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLLSGGSISIMTENPAP-DWLSDRA 3570
++LFEK KL F + +I++ + +I+ E +LL ++ + +P D+L+ ++
Sbjct: 3778 YTSQALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLL---RFTVEHTHLSPVDFLTSQS 3834
Query: 3571 WRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRC 3630
W I A++ + F D ++R +S P +E LP W + QKL++LR
Sbjct: 3835 WSAIKAIAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKK-KSLIQKLILLRA 3893
Query: 3631 LRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKF 3690
+R D++T A+++FV L +++E +L F++S+ TP+ F+LSPG D DL
Sbjct: 3894 MRPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEIL 3953
Query: 3691 AEEMKF---SKKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNCHLAPSWMPALERLIE 3747
+ + F S K +SLGQGQ AE + + + G WV QN HL W+ LE+L+E
Sbjct: 3954 GKRLGFTIDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLE 4013
Query: 3748 HINPDKVHRDFRLWLT--SLPS---NKFPVSILQNGSKMTIEPPRGVRANLLKSYSSLGE 3802
+ HRD+R++++ S P+ + P +L+N K+T EPP G+ ANL + + +
Sbjct: 4014 RFSQGS-HRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQ 4072
Query: 3803 DFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLD 3862
D L C K EFKS+L SLC FH R +FGP G++ Y F GDL IC S L +L+
Sbjct: 4073 DTLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLE 4132
Query: 3863 EYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSPEHSYSASGIYHQI 3922
+P++ L+Y GEI YGG +TDDWDR+ LE+F NP L+ + A G
Sbjct: 4133 ANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPS-LTEDELMLAPGF--AA 4189
Query: 3923 PPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSAG-- 3980
PP D GY YI+ + + P ++GLH NA I F + L T++++QP+++ +G
Sbjct: 4190 PPYLDYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDE 4249
Query: 3981 -SQGREEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVIT 4039
Q EE V++V +IL K+PE N+ +M K V QE R N L++ I
Sbjct: 4250 LGQSTEEKVKNVLDDILEKLPEEFNMAEIMQKNS--NRSPYVLVCFQECERMNILIREIR 4307
Query: 4040 QTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDF 4099
+L+ L +LKG + +S +E +L +TVP+ WS AYPS L+ W DLL R
Sbjct: 4308 ISLEQLDLSLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRE 4367
Query: 4100 LQAWIQD-GIPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQ 4158
L W QD +PAV W+SGFF PQ+FLT +Q ARK +D V + +
Sbjct: 4368 LDTWTQDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGH 4427
Query: 4159 RPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPI 4218
P+ G Y+HGLF+EGARWD +A + E++ KEL M VI+ TP + + + Y CP+
Sbjct: 4428 PPREGAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECPV 4487
Query: 4219 YKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALI 4260
Y+T R +Y+ + + + W+ GVAL+
Sbjct: 4488 YRTKLR---------GPSYIWTFRLKSEEKTAKWVLAGVALL 4520
>gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 1984 bits (5140), Expect = 0.0
Identities = 1171/3340 (35%), Positives = 1833/3340 (54%), Gaps = 192/3340 (5%)
Query: 1002 IFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAF 1061
+F +P+ +Y +L +E + +LW E W I+ EQ++ + +
Sbjct: 1254 LFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFA 1313
Query: 1062 KTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININ 1121
K M K+ K A V LD ++ + + L+NP +R RHW+ L +
Sbjct: 1314 KDMRSLDKEMKTWDAF--VGLD--NTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVK 1369
Query: 1122 VRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKA 1181
+ T A L++NL + + + + + A KE +E+ L ++ WS + F P+
Sbjct: 1370 FKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPR 1429
Query: 1182 TDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQ 1241
T T +LKS + + L+D+ V QN+ S Y F + + SW+ KL V+ W Q
Sbjct: 1430 TGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQ 1489
Query: 1242 RSWLYLEPIF-SSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDSL 1300
R+W +LE IF SEDI QLP +S+R+ + + +K +M++A + V+ S + + L
Sbjct: 1490 RTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKL 1549
Query: 1301 RDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENI 1360
K L + +K L+EYLETKR AFPRFYF+S +LL+ILS DP V HL K F+++
Sbjct: 1550 EALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSL 1609
Query: 1361 ARLLFQED-----LEI-THMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIE 1414
+L F+ D L++ MYS E E + S VE WL V M +++ I
Sbjct: 1610 CKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIP 1669
Query: 1415 KAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEA---LEAG--NLRSQLFPQLCQQ 1469
+A+ Y PR QW+L++P Q+ +WT EV A LE G N + Q
Sbjct: 1670 EAVVTYEEKPREQWILDYPAQI-------WWTTEVGLAFARLEEGYENAIRDYNKKQISQ 1722
Query: 1470 LSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTN 1529
L+ L+ L+ G L+ R + + I+VHA+DVV+K+I E S F W +QLR+ W
Sbjct: 1723 LNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVE---SSQAFTWQAQLRHRWDE 1779
Query: 1530 NDLYIRA--VNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGK 1587
+ A +A+ Y YEYLGN+ RLVITPLTDRCY+TLT +LHL GGAPAGPAGTGK
Sbjct: 1780 EKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGK 1839
Query: 1588 TETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVA 1647
TETTKDLG+AL VFNCS+Q+D+ + G +KGLA GAW CFDEFNRI +EVLSV+A
Sbjct: 1840 TETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIA 1899
Query: 1648 QQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMM 1707
Q+ +Q A + + + F F G I L+P+ +FITMNPGYAGR ELP+NLKALFRP AM+
Sbjct: 1900 VQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMV 1959
Query: 1708 VPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGN 1767
VPD+ +I EI L + GF EA +LA+K T + L E LS QDHYD+G+RA+K+V+ AG+
Sbjct: 1960 VPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGS 2019
Query: 1768 LKRENPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTI---KEEDTDYGILDE 1824
LKR +PS E+ + +RA+RD N+PK + +DL +F G++ DLFP + ++ D ++ ++
Sbjct: 2020 LKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNF---EK 2076
Query: 1825 AIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKG 1884
I+++ L+ + F+ K +QL E VRH + +VG GSGKS + L +LK
Sbjct: 2077 IIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKR 2136
Query: 1885 QPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKW 1944
+P AV+ L+PK++T +L+G + +T EW DG+FS+ +R A + KW
Sbjct: 2137 KPV-------AVD---LDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKW 2186
Query: 1945 YMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCG 2004
+ DG +D +WIE++NTV+DDNK L L+S E I L M ++FE+ L A+PATVSR G
Sbjct: 2187 IILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAG 2246
Query: 2005 MVYLEPSILGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEESISFVRSSVKEVIASTN 2064
++Y+ P+ LG P + W+ + ++ + + LF +L + +R K++
Sbjct: 2247 ILYINPADLGWNPVVSSWIERRK--VQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPE 2304
Query: 2065 CNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSG- 2123
+ ++L LL+C K +P + + EL +F+F+ W+ G
Sbjct: 2305 ITVIQTILYLLECLLTE-------KTVPPDSPRELYEL---YFVFTCFWAFGGAMFQDQL 2354
Query: 2124 ---RTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVK 2180
R FS W NE T+ FP +G +FDY ++ D ++ ++
Sbjct: 2355 VDYRVEFSKW----WINEFKTIKFPSQGTIFDYYIDP----------DTKK------FLP 2394
Query: 2181 WMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDK 2240
W D F + PD +V T +T+++ + +D+L+ PV+ +G GTGK++ + DK
Sbjct: 2395 WTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDK 2454
Query: 2241 LLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPA 2300
L +Y+ + F+ T++ Q ++ L+K+ +GPP + ++FIDD+NMP
Sbjct: 2455 LESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPE 2514
Query: 2301 LETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRH 2360
++ YG P L+RQ MDH WYDR + K++ + +V M P G T+ RL RH
Sbjct: 2515 VDKYGTVAPHTLIRQHMDHRHWYDRHKL-TLKDIHNCQYVACMNPTSGSF-TIDSRLQRH 2572
Query: 2361 FNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMVY 2420
F + + + + I++TIL L ++R + I + LV A + ++
Sbjct: 2573 FCVFAVSFPGQEALTTIYNTILTQHL-------AFRSV---SMAIQRISSQLVAAALALH 2622
Query: 2421 ATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDRL 2480
IT+ LPT K HY FNLRDLS +FQG+L + ++ + L+RLW HE RV+ D++
Sbjct: 2623 QKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKM 2682
Query: 2481 VNEEDRSWFDQLLKRCMEQWEVTFNKVCPF-QPILYGDFMSPGSDVKSYELITSESKMMQ 2539
V+E+D+ ++ +++ F +P ++ F D K Y +T + + +
Sbjct: 2683 VDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPK-YVPVTDMAPLNK 2741
Query: 2540 VIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLA 2599
++ + ++ YN++N A + LVLF DA++HICRI+R L GNALL+GVGGSG+ SL+RLA
Sbjct: 2742 LLVDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLA 2800
Query: 2600 SHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINN 2659
++++ + FQI L K YG+ + + D+ +KA ++N+P FL +D+Q+ E FL IN+
Sbjct: 2801 AYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLIND 2860
Query: 2660 VLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCMSPI 2719
+L SG+IP L+ DE + I+S+MRP ++ G+ T+ + +VR + ++LC SP+
Sbjct: 2861 LLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPV 2920
Query: 2720 GEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQVCV 2779
G V R R R+FP++VNC IDWF+EWP +AL SV+ FL E E E++ I +
Sbjct: 2921 GSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEET---EGIPWEVKASISFFM 2977
Query: 2780 -YIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDK 2838
Y+H +V++ YLA R+NY TPK++LE + ++ L+ +K+ EL R+++GL K
Sbjct: 2978 SYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMK 3037
Query: 2839 LLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEK 2898
L T+ V ++ L L++ + ++ + ++ + + EE+K
Sbjct: 3038 LQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVI 3097
Query: 2899 AKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIM 2958
K + DL +A PAL AA +L LNKN++TE+++ PP V V AV I+
Sbjct: 3098 NKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMIL 3157
Query: 2959 KGIKPKKVPGEKPGTKV--DDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQPYI 3016
PG K+ D W+ K ++ FL+SL KFDK++I + +KA +PY
Sbjct: 3158 TA----------PGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQ 3207
Query: 3017 DNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDE 3076
N F P I S A +C W + +++ V V PKRQAL EA +L Q L
Sbjct: 3208 GNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSR 3267
Query: 3077 AKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQET 3136
K ++ E+ ++ + + + + +K + + + + + + A +L+ GL+ E +RW E+
Sbjct: 3268 IKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAES 3327
Query: 3137 VENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDS-WVKQLRSHNVPH--TSEPTL 3193
VEN + + GDVL+ + FV+Y+G FT +YR L + W+ + + VP T+
Sbjct: 3328 VENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDP 3387
Query: 3194 IGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGL 3253
+ L + + +W GLP+D +S EN I ++RW +D Q Q KWIKN + L
Sbjct: 3388 LSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSE-L 3446
Query: 3254 DVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTV 3313
+L + +L +E AI G L+EN+GE +DP L+P+L + T K+ +K+GD
Sbjct: 3447 KAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKK--GKYIKIGDKE 3504
Query: 3314 IPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAK 3373
+ YH FR+ + TK NPHY PE+ + TLINF ++ GLEDQLL VVA+ERPDLE+ K
Sbjct: 3505 VEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLK 3564
Query: 3374 NQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAE 3433
L S + + LK++ED +L RLS++ GN + D L++ LE +K A+EI+ KV A+
Sbjct: 3565 ANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAK 3624
Query: 3434 QTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADN 3493
TE I+ R Y P A R +L+F ++DL ++P+YQ+SL+ F +F I + A+
Sbjct: 3625 ITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANE 3684
Query: 3494 LKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLL---- 3549
+K+R+ N+ +TYS+Y R LFE+ KL+F + +++ + ++N E +LL
Sbjct: 3685 VKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPF 3744
Query: 3550 SGGSISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHRE 3609
G +S + D+L + W I ALS + F + SD ++ + +S P +E
Sbjct: 3745 KAGVVSPV------DFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKE 3798
Query: 3610 PLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNS 3669
P W QKL ++RCLR D++T A+++FV + +F+E ++ S +++S+
Sbjct: 3799 IFPKEWKNKT-ALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSP 3857
Query: 3670 TTPLIFVLSPGTDPAADLYKFAEEMKFS---KKLSAISLGQGQGPRAEAMMRSSIERGKW 3726
+T + F+LSPG DP D+ +++ F+ KL +SLGQGQ AE + + E+G W
Sbjct: 3858 STSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHW 3917
Query: 3727 VFFQ--------NCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNK-----FPVS 3773
V Q N HL W+ L++ +EH + H D+R+++++ P+ P
Sbjct: 3918 VILQVRGGQHCRNIHLVARWLGTLDKKLEHYSTGS-HEDYRVFISAEPAPSPETHIIPQG 3976
Query: 3774 ILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRK 3833
IL+N K+T EPP G+ ANL K+ +D L C K MEFK +L +LC FH ERRK
Sbjct: 3977 ILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRK 4036
Query: 3834 FGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRC 3893
FG G+N Y F +GDL I I+ L +L+ +P+ L+Y GEI YGG +TDDWDRR
Sbjct: 4037 FGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRL 4096
Query: 3894 IMNILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNA 3953
L ++ ++L + + QIPP D GY YI + P ++GLH NA
Sbjct: 4097 CRTYLAEYIRTEMLEGDVLLAPG---FQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNA 4153
Query: 3954 NITFAQNETFALLGTIIQLQPKSSSAGSQ---GREEI----------------------- 3987
I F + L T++++QPK + +G+ REE
Sbjct: 4154 EIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGC 4213
Query: 3988 ------VEDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQT 4041
V+ V +IL K+PE N+ +MAK + V QE R N L + ++
Sbjct: 4214 PGTGFQVKAVLDDILEKIPETFNMAEIMAK--AAEKTPYVVVAFQECERMNILTNEMRRS 4271
Query: 4042 LQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQ 4101
L++L LKG + +++ +E ++ +L+ +TVP+ W A+AYPS+ L++W DLL R+ L+
Sbjct: 4272 LKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELE 4331
Query: 4102 AWIQD-GIPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRP 4160
AW D +P W++GFF PQ+FLT +Q+ ARK +D + +V + ++T P
Sbjct: 4332 AWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPP 4391
Query: 4161 QVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYK 4220
+ G Y++GLF+EGARWD + +AE++ KEL M VI++ P + + ++ Y CP+YK
Sbjct: 4392 REGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYK 4451
Query: 4221 TLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALI 4260
T R T YV + T + WI VAL+
Sbjct: 4452 TRIRGPT---------YVWTFNLKTKEKAAKWILAAVALL 4482
>gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 1981 bits (5131), Expect = 0.0
Identities = 1170/3340 (35%), Positives = 1832/3340 (54%), Gaps = 192/3340 (5%)
Query: 1002 IFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAF 1061
+F +P+ +Y +L +E + +LW E W I+ EQ++ + +
Sbjct: 1254 LFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFA 1313
Query: 1062 KTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININ 1121
K M K+ K A V LD ++ + + L+NP +R RHW+ L +
Sbjct: 1314 KDMRSLDKEMKTWDAF--VGLD--NTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVK 1369
Query: 1122 VRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKA 1181
+ T A L++NL + + + + + A KE +E+ L ++ WS + F P+
Sbjct: 1370 FKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPR 1429
Query: 1182 TDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQ 1241
T T +LKS + + L+D+ V QN+ S Y F + + SW+ KL V+ W Q
Sbjct: 1430 TGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQ 1489
Query: 1242 RSWLYLEPIF-SSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDSL 1300
R+W +LE IF SEDI QLP +S+R+ + + +K +M++A + V+ S + + L
Sbjct: 1490 RTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKL 1549
Query: 1301 RDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENI 1360
K L + +K L+EYLETKR AFPRFYF+S +LL+ILS DP V HL K F+++
Sbjct: 1550 EALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSL 1609
Query: 1361 ARLLFQED-----LEI-THMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIE 1414
+L F+ D L++ MYS E E + S VE WL V M +++ I
Sbjct: 1610 CKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIP 1669
Query: 1415 KAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEA---LEAG--NLRSQLFPQLCQQ 1469
+A+ Y PR QW+L++P Q+ +WT EV A LE G N + Q
Sbjct: 1670 EAVVTYEEKPREQWILDYPAQI-------WWTTEVGLAFARLEEGYENAIKDYNKKQISQ 1722
Query: 1470 LSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTN 1529
L+ L+ L+ G L+ R + + I+VHA+DVV+K+I E S F W +QLR+ W
Sbjct: 1723 LNVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMIVE---SSQAFTWQAQLRHRWDE 1779
Query: 1530 NDLYIRA--VNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGK 1587
+ A +A+ Y YEYLGN+ RLVITPLTDRCY+TLT +LHL GGAPAGPAGTGK
Sbjct: 1780 EKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGK 1839
Query: 1588 TETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVA 1647
TETTKDLG+AL VFNCS+Q+D+ + G +KGLA GAW CFDEFNRI +EVLSV+A
Sbjct: 1840 TETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIA 1899
Query: 1648 QQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMM 1707
Q+ +Q A + + + F F G I L+P+ +FITMNPGYAGR ELP+NLKALFRP AM+
Sbjct: 1900 VQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMV 1959
Query: 1708 VPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGN 1767
VPD+ +I EI L + GF EA +LA+K T + L E LS QDHYD+G+RA+K+V+ AG+
Sbjct: 1960 VPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGS 2019
Query: 1768 LKRENPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTI---KEEDTDYGILDE 1824
LKR +PS E+ + +RA+RD N+PK + +DL +F G++ DLFP + ++ D ++ ++
Sbjct: 2020 LKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNF---EK 2076
Query: 1825 AIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKG 1884
I+++ L+ + F+ K +QL E VRH + +VG GSGKS + L +LK
Sbjct: 2077 IIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKR 2136
Query: 1885 QPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKW 1944
+P AV+ L+PK++T +L+G + +T EW DG+FS+ +R A + KW
Sbjct: 2137 KPV-------AVD---LDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKW 2186
Query: 1945 YMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCG 2004
+ DG +D +WIE++NTV+DDNK L L+S E I L M ++FE+ L A+PATVSR G
Sbjct: 2187 IILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAG 2246
Query: 2005 MVYLEPSILGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEESISFVRSSVKEVIASTN 2064
++Y+ P+ LG P + W+ + ++ + + LF +L + +R K++
Sbjct: 2247 ILYINPADLGWNPVVSSWIERRK--VQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPE 2304
Query: 2065 CNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSG- 2123
+ ++L LL+C K +P + + EL +F+F+ W+ G
Sbjct: 2305 ITVIQTILYLLECLLTE-------KTVPPDSPRELYEL---YFVFTCFWAFGGAMFQDQL 2354
Query: 2124 ---RTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVK 2180
R FS W NE T+ FP +G +FDY ++ D ++ ++
Sbjct: 2355 VDYRVEFSKW----WINEFKTIKFPSQGTIFDYYIDP----------DTKK------FLP 2394
Query: 2181 WMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDK 2240
W D F + PD +V T +T+++ + +D+L+ PV+ +G GTGK++ + DK
Sbjct: 2395 WTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDK 2454
Query: 2241 LLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPA 2300
L +Y+ + F+ T++ Q ++ L+K+ +GPP + ++FIDD+NMP
Sbjct: 2455 LESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPE 2514
Query: 2301 LETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRH 2360
++ YG P L+RQ MDH WYDR + K++ + +V M P G T+ RL RH
Sbjct: 2515 VDKYGTVAPHTLIRQHMDHRHWYDRHKL-TLKDIHNCQYVACMNPTSGSF-TIDSRLQRH 2572
Query: 2361 FNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMVY 2420
F + + + + I++TIL L ++R + I + LV A + ++
Sbjct: 2573 FCVFAVSFPGQEALTTIYNTILTQHL-------AFRSV---SMAIQRISSQLVAAALALH 2622
Query: 2421 ATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDRL 2480
IT+ LPT K HY FNLRDLS +FQG+L + ++ + L+RLW HE RV+ D++
Sbjct: 2623 QKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKM 2682
Query: 2481 VNEEDRSWFDQLLKRCMEQWEVTFNKVCPF-QPILYGDFMSPGSDVKSYELITSESKMMQ 2539
V+E+D+ ++ +++ F +P ++ F D K Y +T + + +
Sbjct: 2683 VDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPK-YVPVTDMAPLNK 2741
Query: 2540 VIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLA 2599
++ + ++ YN++N A + LVLF DA++HICRI+R L GNALL+GVGGSG+ SL+RLA
Sbjct: 2742 LLVDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLA 2800
Query: 2600 SHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINN 2659
++++ + FQI L K YG+ + + D+ +KA ++N+P FL +D+Q+ E FL IN+
Sbjct: 2801 AYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLIND 2860
Query: 2660 VLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCMSPI 2719
+L SG+IP L+ DE + I+S+MRP ++ G+ T+ + +VR + ++LC SP+
Sbjct: 2861 LLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPV 2920
Query: 2720 GEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQVCV 2779
G V R R R+FP++VNC IDWF+EWP +AL SV+ FL E E E++ I +
Sbjct: 2921 GSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEET---EGIPWEVKASISFFM 2977
Query: 2780 -YIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDK 2838
Y+H +V++ YLA R+NY TPK++LE + ++ L+ +K+ EL R+++GL K
Sbjct: 2978 SYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMK 3037
Query: 2839 LLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEK 2898
L T+ V ++ L L++ + ++ + ++ + + EE+K
Sbjct: 3038 LQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVI 3097
Query: 2899 AKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIM 2958
K + DL +A PAL AA +L LNKN++TE+++ PP V V AV I+
Sbjct: 3098 NKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMIL 3157
Query: 2959 KGIKPKKVPGEKPGTKV--DDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQPYI 3016
PG K+ D W+ K ++ FL+SL KFDK++I + +KA +PY
Sbjct: 3158 TA----------PGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQ 3207
Query: 3017 DNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDE 3076
N F P I S A +C W + +++ V V PKRQAL EA +L Q L
Sbjct: 3208 GNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSR 3267
Query: 3077 AKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQET 3136
K ++ E+ ++ + + + + +K + + + + + + A +L+ GL+ E +RW E+
Sbjct: 3268 IKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAES 3327
Query: 3137 VENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDS-WVKQLRSHNVPH--TSEPTL 3193
VEN + + GDVL+ + FV+Y+G FT +YR L + W+ + + VP T+
Sbjct: 3328 VENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDP 3387
Query: 3194 IGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGL 3253
+ L + + +W GLP+D +S EN I ++RW +D Q Q KWIKN + L
Sbjct: 3388 LSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSE-L 3446
Query: 3254 DVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTV 3313
+L + +L +E AI G L+EN+GE +DP L+P+L + T K+ +K+GD
Sbjct: 3447 KAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKK--GKYIKIGDKE 3504
Query: 3314 IPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAK 3373
+ YH FR+ + TK NPHY PE+ + TLINF ++ GLEDQLL VVA+ERPDLE+ K
Sbjct: 3505 VEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLK 3564
Query: 3374 NQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAE 3433
L S + + LK++ED +L RLS++ GN + D L++ LE +K A+EI+ KV A+
Sbjct: 3565 ANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAK 3624
Query: 3434 QTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADN 3493
TE I+ R Y P A R +L+F ++DL ++P+YQ+SL+ F +F I + A+
Sbjct: 3625 ITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANE 3684
Query: 3494 LKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLL---- 3549
+K+R+ N+ +TYS+Y R LFE+ KL+F + +++ + ++N E +LL
Sbjct: 3685 VKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPF 3744
Query: 3550 SGGSISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHRE 3609
G +S + D+L + W I ALS + F + SD ++ + +S P +E
Sbjct: 3745 KAGVVSPV------DFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKE 3798
Query: 3610 PLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNS 3669
P W QKL ++RCLR D++T A+++FV + +F+E ++ S +++S+
Sbjct: 3799 IFPKEWKNKT-ALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSP 3857
Query: 3670 TTPLIFVLSPGTDPAADLYKFAEEMKFS---KKLSAISLGQGQGPRAEAMMRSSIERGKW 3726
+T + F+LSPG DP D+ +++ F+ KL +SLGQGQ AE + + E+G W
Sbjct: 3858 STSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHW 3917
Query: 3727 VFFQ--------NCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNK-----FPVS 3773
V Q N HL W+ L++ +E + H D+R+++++ P+ P
Sbjct: 3918 VILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGS-HEDYRVFISAEPAPSPETHIIPQG 3976
Query: 3774 ILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRK 3833
IL+N K+T EPP G+ ANL K+ +D L C K MEFK +L +LC FH ERRK
Sbjct: 3977 ILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRK 4036
Query: 3834 FGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRC 3893
FG G+N Y F +GDL I I+ L +L+ +P+ L+Y GEI YGG +TDDWDRR
Sbjct: 4037 FGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRL 4096
Query: 3894 IMNILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNA 3953
L ++ ++L + + QIPP D GY YI + P ++GLH NA
Sbjct: 4097 CRTYLAEYIRTEMLEGDVLLAPG---FQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNA 4153
Query: 3954 NITFAQNETFALLGTIIQLQPKSSSAGSQ---GREEI----------------------- 3987
I F + L T++++QPK + +G+ REE
Sbjct: 4154 EIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGC 4213
Query: 3988 ------VEDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQT 4041
V+ V +IL K+PE N+ +MAK + V QE R N L + ++
Sbjct: 4214 PGTGFQVKAVLDDILEKIPETFNMAEIMAK--AAEKTPYVVVAFQECERMNILTNEMRRS 4271
Query: 4042 LQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQ 4101
L++L LKG + +++ +E ++ +L+ +TVP+ W A+AYPS+ L++W DLL R+ L+
Sbjct: 4272 LKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELE 4331
Query: 4102 AWIQD-GIPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRP 4160
AW D +P W++GFF PQ+FLT +Q+ ARK +D + +V + ++T P
Sbjct: 4332 AWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPP 4391
Query: 4161 QVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYK 4220
+ G Y++GLF+EGARWD + +AE++ KEL M VI++ P + + ++ Y CP+YK
Sbjct: 4392 REGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYK 4451
Query: 4221 TLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALI 4260
T R T YV + T + WI VAL+
Sbjct: 4452 TRIRGPT---------YVWTFNLKTKEKAAKWILAAVALL 4482
>gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]
Length = 3092
Score = 1497 bits (3876), Expect = 0.0
Identities = 915/2330 (39%), Positives = 1304/2330 (55%), Gaps = 207/2330 (8%)
Query: 424 MRKGPSVLEHLSSLAREVSLDYERSMNKINFDHVVSSKPETFSYVTLPKKEEEQVPERGL 483
+++G E L SL EVS D+E SM + V+ P V + E +PE +
Sbjct: 127 LKEGKEREELLESLINEVSSDFENSMKRYLVQSVLVKPP-----VKSLEDEGGPLPESPV 181
Query: 484 ---VSVPKYHFWEQKEDFTFVSLLTRPEVITALSKVRAECNKVTAMSLFHSSLSKYSHLE 540
S P + + Q + F +L +I K+ + T L
Sbjct: 182 GLDYSNPWHSSYVQARNQIFSNL----HIIHPTMKMLLDLGYTTFADTV---------LL 228
Query: 541 EFEQIQSQTFSQVQMFLKDSWISSLKVAMRSSLRDMSKGWY----NLYETN--WEVYLMS 594
+F I+++ + D L + R++ + WY NL+ E
Sbjct: 229 DFTGIRAKGPIDCESLKTD-----LSIQTRNAEEKIMNTWYPKVINLFTKKEALEGVKPE 283
Query: 595 KLRKLMELVKYMLQDTLRFLVQDSLASFSQFISDTCCSVLNCTDDMVWGDDLINSPYRPR 654
KL V ++ + L+ L++ ++ F + P +
Sbjct: 284 KLDAFYSCVSTLMSNQLKDLLRRTVEGFVKLFD----------------------PKDQQ 321
Query: 655 KNPLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATHAVPQLEKLVMEDIFISGD- 713
+ P+F ++L D + + + E ++L+L ++ A V + ++SG
Sbjct: 322 RLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPS------WLSGTS 375
Query: 714 -PLLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNN----NDIASFLKT 768
P+ L E ++ T+ +AV + L+ K Y Y+E N ++T
Sbjct: 376 TPVNLDTELPEHVLHWAVDTLKAAVHRN---LEGARKHYETYVEKYNWLLDGTAVENIET 432
Query: 769 YQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYIN-------TDNVKQSLSKKR 821
+QT+ E E + L SL S I++ P +I+ +++K L+ K
Sbjct: 433 FQTEDHTFDEYTEFIEKFL--------SLASEIMLLPQWIHYTMVRLDCEDLKTGLTNKA 484
Query: 822 KALATSVLDILAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLVGL 881
KA A +L+ +A KE + IC EF +I + P + EE+ +L +++ R VG+
Sbjct: 485 KAFANILLNDIASKYRKENECICSEFEAIKEHALKVPETTEEMMDLISYVE--KARTVGI 542
Query: 882 EERIVKVMDDYQVMDEFL--YNLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFR 939
EE I+++ + + M FL + +D WP KI + E++E
Sbjct: 543 EELILRIQESKRQMSYFLDVFLFPQEDLALNATVLMWPRKINPIFD-------ENDELIE 595
Query: 940 KIQIMDQNNFQEKLEGLQLVVAG-------FSIHVEISRAHEIANEVRRVKKQLKDCQQL 992
+ +N K E L L + F+ E+ R + +VR+++K++++ ++
Sbjct: 596 NAKHKKENELMAKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEA 655
Query: 993 AMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQ 1052
N E +F +T Y +L ++ +PY + W R + WM+ ++ E
Sbjct: 656 VQFINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGES 715
Query: 1053 LEKNVVEAFKTMHKCVKQF--KDMPACQEVALDIRAR------IEEFKPYIPLIQGLRNP 1104
+E +V E + + K +K F K QE R R IEE I R
Sbjct: 716 MEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEEPKDNATITMCR-- 773
Query: 1105 GMRIRHWETLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDK 1164
MR RHW+ +S + ++ P + T + L++NL ++E ++ A KE+++E+A++
Sbjct: 774 -MRARHWKQISEIVGYDLTPDSGTTLRKVLKLNLTPYLEQFEVISAGASKEFSLEKAMNT 832
Query: 1165 MEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWE 1224
M W I F++ Y+ T IL S DE +LDD I+ TQ M SP+ KPFE I +WE
Sbjct: 833 MIGTWEDIAFHISLYRDTGVCILSSVDEIQAILDDQIIKTQTMRGSPFIKPFEHEIKAWE 892
Query: 1225 NKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYEN 1284
++L QE ++EWL Q WLYLEPIF SEDI QQ+P E +++QT++R W+ IMK ++
Sbjct: 893 DRLIRIQETIDEWLKVQAQWLYLEPIFCSEDIMQQMPEEGRQFQTVDRHWRDIMKFCAKD 952
Query: 1285 REVINVCSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTK 1344
+V+ S +L+ L++CN++L+ + KGL+ YLE KR FPRF+FLS+DE+LEILS+TK
Sbjct: 953 PKVLAATSLTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSETK 1012
Query: 1345 DPTAVQPHLRKCFENIARLLFQEDLEITHMYSAEGEEVQLCFSIYPSSN---VEDWLREV 1401
DP VQPHL+KCFE IA+L F +L+I MYS+EGE V+L I S+ VE WL +V
Sbjct: 1013 DPLRVQPHLKKCFEGIAKLEFLPNLDIKAMYSSEGERVELIALISTSAARGAVEKWLIQV 1072
Query: 1402 ERSMKASVHDIIEKAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLR-S 1460
E M SVHD+I A AYP R WV WPGQV + Q +WT E E + G
Sbjct: 1073 EDLMLRSVHDVIAAARLAYPESARRDWVREWPGQVVLCISQMFWTSETQEVISGGTEGLK 1132
Query: 1461 QLFPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWI 1520
+ + +L QL+++V LVRGKLS+ R L AL+ I+VHA+DVV +I+ V DF W+
Sbjct: 1133 KYYKELQNQLNEIVELVRGKLSKQTRTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWL 1192
Query: 1521 SQLRYYWTNNDLYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPA 1580
+QLRYYW N + +R +N Y YEYLGNS RLVITPLTDRCY TL GA +L GGAP
Sbjct: 1193 AQLRYYWENENARVRIINCNVKYAYEYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPE 1252
Query: 1581 GPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDI 1640
GPAGTGKTETTKDL KALA+Q VVFNCSD LD++AMGKFFKGLAS+GAWACFDEFNRI++
Sbjct: 1253 GPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIEL 1312
Query: 1641 EVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKAL 1700
EVLSVVAQQI IQ+A QQ++ F+FEG E+ L P+C V ITMNPGYAGR+ELPDNLK L
Sbjct: 1313 EVLSVVAQQILCIQRAIQQKLVVFVFEGTELKLNPNCFVAITMNPGYAGRSELPDNLKVL 1372
Query: 1701 FRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKT 1760
FR VAMMVP+YA+I EISLYS+GF A L+ KI T++L SEQLSSQ HYD+GMRAVK
Sbjct: 1373 FRTVAMMVPNYALIAEISLYSYGFLNARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKA 1432
Query: 1761 VISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYG 1820
V+ AAGNLK + P+ NE+++ LR+I+DVN PKFL D+ LF+GI SDLFP IK + DY
Sbjct: 1433 VLVAAGNLKLKYPNENEDILLLRSIKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYH 1492
Query: 1821 ILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMT 1880
E EAC NL+ V+ FL K IQ YE +VRHG MLVG + K+ VLA +T
Sbjct: 1493 EFLECAHEACNVHNLQPVKFFLEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLT 1552
Query: 1881 SLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDT 1940
+ G E V Y +NPKSITMGQL+G+FD ++HEWTDGI ++ R A++
Sbjct: 1553 LMNEH---GYGEEEKVIYRTVNPKSITMGQLFGQFDPVSHEWTDGIVANTFREFALSETP 1609
Query: 1941 NKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATV 2000
++KW +FDGP+D +WIE+MNTVLDDNKKLCL SGEII+++ M+++FE DL+ ASPATV
Sbjct: 1610 DRKWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATV 1669
Query: 2001 SRCGMVYLEPSILGLMPFIECWLRKLP-PLLKP-YEEHFKALFVSFLEESISFVRSSVKE 2058
SRCGM+YLEPS LG P + WL L PL +P Y+ + LF + S+ + +
Sbjct: 1670 SRCGMIYLEPSQLGWEPLVSSWLNSLKGPLCEPEYQALLRGLFAWLIPPSL-----NQRV 1724
Query: 2059 VIASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIVELI---EPWFIFSLIWSV 2115
+ N T + K+L F K +P + ++ + FIFSLIWS+
Sbjct: 1725 ELFQLNYLYTTIVSKILKILI-TFRISNYFKYVPLKTQCTFIKFFLHQQACFIFSLIWSI 1783
Query: 2116 GATGDSSGRTSFSHWLRLKM-----ENE------QLTLLFPEEGLVFDYRLEDAGISGTN 2164
G + D+ GR F ++RL + EN + F E+GLV+DY
Sbjct: 1784 GGSCDTDGRRVFDTFIRLIILGKDDENPVPDSVGKWECPFDEKGLVYDYMY--------- 1834
Query: 2165 DSEDEEEEYKQVAWVKWMDSSAPFTMVPDTN-------YCNIIVPTMDTVQMSHLLDMLL 2217
E + WV W + ++ +TN +IIVPTMDT++ + L+D+ +
Sbjct: 1835 ------ELKNKGRWVHWNE------LIKNTNLGDKQIKIQDIIVPTMDTIRYTFLMDLSI 1882
Query: 2218 TNKKPVLCIGPTGTGKTLTISDKLLKNLALD-YISHFLTFSARTSANQTQDFIDSKLDKR 2276
T KP+L +GPTGTGK++ + DKL+ +L D Y ++ SARTSANQ Q+ I ++LDKR
Sbjct: 1883 TYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLSARTSANQVQNIIMARLDKR 1942
Query: 2277 RKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVD 2336
RKGVFGPP+G+ I FIDD+NMPALE YGAQPPIELLRQ+ D G WYD K LVD
Sbjct: 1943 RKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFFDCGHWYDLKDTSKI-TLVD 2001
Query: 2337 INFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYR 2396
I + AMGPPGGGRN VTPR +RHFN S + + RIFS+I+ +L
Sbjct: 2002 IELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVRIFSSIVAFYL--------RT 2053
Query: 2397 ERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPA 2456
P P +V T+ +Y LLPTP KSHYTFNLRD S+V +G L+ +
Sbjct: 2054 HEFP--PEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRVIRGCLLIERD 2111
Query: 2457 KVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCM-EQWEVTFNKVC------- 2508
V ++ ++RL+ HE RVF DRL+N++DR W QL K + + ++ +F+ +
Sbjct: 2112 AVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKESFHSIFSHLRKQN 2171
Query: 2509 ------PFQPILYGDFMSPG--SDVKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVL 2560
+ +++GD+M+P D + Y I + V+++ +++YNQ + ++ LV+
Sbjct: 2172 APVTEEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQCLDEYNQTHKTRMNLVI 2231
Query: 2561 FMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSE 2620
F + H+ RI R L+Q+ GNALL+G+GGSGR SLTRLA+ MA+ FQ E+SK+YGM+E
Sbjct: 2232 FRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAKMHIFQPEISKSYGMNE 2291
Query: 2621 WRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLY 2670
WR+D+K + +P+T D + K LE LN NLY
Sbjct: 2292 WREDMKSFIA------VPVTNRIVDNKSK---ILEKRLRYLNDHFTYNLY 2332
Score = 780 bits (2014), Expect = 0.0
Identities = 388/780 (49%), Positives = 525/780 (67%), Gaps = 13/780 (1%)
Query: 3494 LKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLLSGG- 3552
L+KR+ +N + TY+LY N+CRSLFEK KL+F+FLLC +++ +I E +LL+GG
Sbjct: 2316 LEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLLTGGV 2375
Query: 3553 SISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHREPLP 3612
S+ +NP P WL D++W +I S P F F +H+ E+R I+DS EPH P
Sbjct: 2376 SLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIYDSKEPHNAKFP 2435
Query: 3613 GIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTP 3672
D+ L++ QK+++LRCLR DK+T A+ ++V L +F+EP +L+ + DSN T P
Sbjct: 2436 APMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDSNCTIP 2495
Query: 3673 LIFVLSPGTDPAADLYKFAEEMKFS-KKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQN 3731
LIFVLSPG DP A L KFA + S K AISLGQGQGP A M++++IE G WV QN
Sbjct: 2496 LIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTWVCLQN 2555
Query: 3732 CHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVRA 3791
CHLA SWMP LE++ E + + FRLWLTS PS+KFPV+ILQNG KMT EPP G+R
Sbjct: 2556 CHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSKFPVTILQNGVKMTNEPPTGLRL 2615
Query: 3792 NLLKSYSS---LGEDFLNSCH-KVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTD 3847
NLL+SY + +F C K + ++ LL +C FH ER+KFGPLG+NIPY F +
Sbjct: 2616 NLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWNIPYGFNE 2675
Query: 3848 GDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVL 3907
DLRI I QL++F++EYD IP++ + Y GE NYGGRVTDDWDRR ++ +L DFYN ++
Sbjct: 2676 SDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDDWDRRLLLTMLADFYNLYIV 2735
Query: 3908 -SPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALL 3966
+P + +S SG Y PP Y+ +IK LP PEIFGLH+N +I+ +T L
Sbjct: 2736 ENPHYKFSPSGNYFA-PPKGTYEDYIEFIKKLPFTQHPEIFGLHENVDISKDLQQTKTLF 2794
Query: 3967 GTIIQLQPKSSSAGSQGR-EEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLV 4025
+++ Q S G+ G ++I+ ++T++IL K+P +++ + KYPV YEESMNTVLV
Sbjct: 2795 ESLLLTQGGSKQTGASGSTDQILLEITKDILNKLPSDFDIEMALRKYPVRYEESMNTVLV 2854
Query: 4026 QEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKP 4085
QE+ R+N L+ I TL+DL KA+KG+VVM S LE ++ SL VPE+W+ ++YPSLKP
Sbjct: 2855 QEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIWAKRSYPSLKP 2914
Query: 4086 LSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFD 4145
L S++ D L RL+FLQ W G P VFW+SGFFF QAFLTG +QN+ARK+ ID + ++
Sbjct: 2915 LGSYITDFLARLNFLQDWYNSGKPCVFWLSGFFFTQAFLTGAMQNYARKYTTPIDLLGYE 2974
Query: 4146 FKVMFEAPSELTQ-RPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTP 4204
F+V+ PS+ + P+ G YIHGL+L+GARWD E+ LAE PK L+ M +IW+ PT
Sbjct: 2975 FEVI---PSDTSDTSPEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPIIWIKPTQ 3031
Query: 4205 NRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALICALD 4264
+ D Y+CP+YKT R GTLSTTGHSTN+VIA+ + T QP RHWIKRGVAL+C LD
Sbjct: 3032 KSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALLCQLD 3091
>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
Length = 4646
Score = 1384 bits (3581), Expect = 0.0
Identities = 972/3454 (28%), Positives = 1692/3454 (48%), Gaps = 329/3454 (9%)
Query: 1011 DKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQ 1070
+++ ++E Q +W+ S + P ++ +L +N + + Q
Sbjct: 1317 ERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQN-------LDALLNQ 1369
Query: 1071 FKDMPAC--QEVALDIRARIEEFKPYIP---LIQGLRNPGMRIRHWETLSNQININVRPK 1125
K PA Q + + R+ K Y+ L+ L++ ++ RHW+ L ++++N
Sbjct: 1370 LKSFPARLRQYASYEFVQRL--LKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNW-VV 1426
Query: 1126 ANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKATDTY 1185
+ LT + +++LQ + + V VA E A+E+ L ++ + W+T +++ Y+
Sbjct: 1427 SELTLGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQ-NKCR 1485
Query: 1186 ILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWL 1245
+++ D+ + +HI M SPY K FE+ SWE+KL + + W++ QR W+
Sbjct: 1486 LIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWV 1545
Query: 1246 YLEPIFS-SEDINQQLPVESKRYQTMERIWKKIMKNAYEN---REVINVCSDLRMLDSLR 1301
YLE IF+ S DI LPVE++R+Q++ + +MK ++ +V+N+ R L+ L
Sbjct: 1546 YLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLA 1605
Query: 1302 DCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIA 1361
D +L +QK L EYLE +RS+FPRFYF+ D++LLEI+ +K+ +Q H +K F ++
Sbjct: 1606 D---LLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVS 1662
Query: 1362 RLLFQEDLEIT-HMYSAEGEEVQLC--FSIYPSSNVEDWLREVERSMKASVHDIIEKAI- 1417
++ ED + + S EGEEV SI + +WL VE+ M+ ++ ++ +++
Sbjct: 1663 SIILNEDNSVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVT 1722
Query: 1418 ------RAYPTMPRTQ--WVLNWPGQVTIAGCQTYWTMEVAEAL-------EAGNLRSQL 1462
+A P T W+ + Q+ + Q W+ V AL +A L S L
Sbjct: 1723 EVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVL 1782
Query: 1463 FPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQ 1522
+ L+ L V + ++R L LI VH +DV LI+ + + F+W+SQ
Sbjct: 1783 -SNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQ 1841
Query: 1523 LRYYWTNND------LYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFG 1576
+R+Y+ L I+ NA+F YG+EYLG +LV TPLTDRCYLT+T AL + G
Sbjct: 1842 MRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLG 1901
Query: 1577 GAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFN 1636
G+P GPAGTGKTE+ K LG L +VFNC + DF AMG+ F GL GAW CFDEFN
Sbjct: 1902 GSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFN 1961
Query: 1637 RIDIEVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLV-----------PSCAVFITMNP 1685
R++ +LS V+QQ+ IQ+A ++ ++ P+ P A+FITMNP
Sbjct: 1962 RLEERMLSAVSQQVQCIQEALREHSNP-NYDKTSAPITCELLNKQVKVSPDMAIFITMNP 2020
Query: 1686 GYAGRTELPDNLKALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQL 1745
GYAGR+ LPDNLK LFR +AM PD +I ++ LYS GF A VLA KI FKL EQL
Sbjct: 2021 GYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQL 2080
Query: 1746 SSQDHYDFGMRAVKTVISAAGNLKREN---------------------PSMNEELICLRA 1784
SSQ HYDFG+RA+K+V+ +AGN+KRE ++ E+ I +++
Sbjct: 2081 SSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQS 2140
Query: 1785 IRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEG---- 1840
+ + VPK + ED+ L ++SD+FP ++ + L E +++ C+ L +G
Sbjct: 2141 VCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVG 2200
Query: 1841 --FLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNY 1898
++ K +QLY+ T + HGLM+VGP+GSGKS +RVL A+ L+G ++
Sbjct: 2201 GMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVA--------- 2251
Query: 1899 YVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRA--GAITSDTNKK-WYMFDGPVDAIW 1955
++++PK+I+ LYG D T EWTDG+F+ +R ++ + K+ W +FDG VD W
Sbjct: 2252 HIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEW 2311
Query: 1956 IENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGL 2015
+EN+N+VLDDNK L L +GE + L + +MFEVQDL A+ ATVSRCGMV+ +L
Sbjct: 2312 VENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLST 2371
Query: 2016 MPFIECWLRKLPPL------------LKPYEEHFKALFVSFLEESISFVRSSVKEVIAST 2063
+L +L + K E+ + L+ I +++ + ++
Sbjct: 2372 DMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPMLQ--IQRDAATIMQPYFTS 2429
Query: 2064 NCNLTMSL-----------LKLLDCFFKPF-LPREGLKKIPSE---------KLSRIVEL 2102
N +T +L L L C F + + + + ++ ++
Sbjct: 2430 NGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERY 2489
Query: 2103 IEPWFIFSLIWSVGATGDSSGRTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISG 2162
I+ + +++++WS+ R ++R + L + DY + +G
Sbjct: 2490 IQRYLVYAILWSLSGDSRLKMRAELGEYIR---RITTVPLPTAPNIPIIDYEVSISG--- 2543
Query: 2163 TNDSEDEEEEYKQVAWVKWMDSSAPFTMVPDTNYC--NIIVPTMDTVQMSHLLDMLLTNK 2220
W W + P V +++VPT+DTV+ LL L
Sbjct: 2544 --------------EWSPWQ-AKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEH 2588
Query: 2221 KPVLCIGPTGTGKTLTISDKLLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKRR--K 2278
KP++ GP G+GKT+T+ L ++ + L FS+ T+ D + RR
Sbjct: 2589 KPLVLCGPPGSGKTMTLFSALRALPDMEVVG--LNFSSATTPELLLKTFDHYCEYRRTPN 2646
Query: 2279 GVFGPP--LGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVD 2336
GV P LG+ + F D++N+P ++ YG Q I +RQ ++HGG+Y R + L
Sbjct: 2647 GVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFY-RTSDQTWVKLER 2705
Query: 2337 INFVCAMGPPGG-GRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSY 2395
I FV A PP GR ++ R +RH + S +I+ T
Sbjct: 2706 IQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTF-------------N 2752
Query: 2396 RERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMA-D 2454
R + P + + EPL A + Y T++ + + HY ++ R++++ +G+ A
Sbjct: 2753 RAMLRLIPSLRTYAEPLTAAMVEFY-TMSQERFTQDTQPHYIYSPREMTRWVRGIFEALR 2811
Query: 2455 PAKVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKR-CMEQWEVTFNKVCPFQPI 2513
P + L+R+W HE R+F+DRLV +E+R W D+ + ++ + + +PI
Sbjct: 2812 PLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPI 2871
Query: 2514 LYGDFMSPGSDVKSYELITSESKMMQVIEEYIEDYNQI---NTAKLKLVLFMDAMSHICR 2570
LY +++S K Y + E + +Y++ ++ + LVLF + + H+ R
Sbjct: 2872 LYSNWLS-----KDYIPVDQEE-----LRDYVKARLKVFYEEELDVPLVLFNEVLDHVLR 2921
Query: 2571 ISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLL 2630
I R RQ G+ LL+GV G+G+++L+R + M +QI++ + Y ++ +D++ VL
Sbjct: 2922 IDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLR 2981
Query: 2631 KAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQG 2690
++G +N I F+ ++ + + FLE +N +L +G++P L+ DE +++ + Q++G
Sbjct: 2982 RSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEG 3041
Query: 2691 LQ-PTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEA 2749
L + L +T +V N+H+V M+P E + R P+L N C ++WF +W EA
Sbjct: 3042 LMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEA 3101
Query: 2750 LKSVATVFLNEIP-----------------ELESSQEEIQGLIQVCVYIHQSVSKKCIEY 2792
L V F +++ +L + ++ CV++HQ++ +
Sbjct: 3102 LYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARL 3161
Query: 2793 LAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQED 2852
R +TP+ YL+ ++ ++ L +K+ EL+ + + GL K+ T + V +++ D
Sbjct: 3162 AKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRD 3221
Query: 2853 LESMHPLLE---EAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDA 2909
L LE AA D + M + + E + V ++EI+ E+ K Q + D
Sbjct: 3222 LRIKSQELEVKNAAANDKLKKMVKDQ-----QEAEKKKVMSQEIQ--EQLHKQQEVIADK 3274
Query: 2910 Q----KDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKK 2965
Q +DLD+ PA+ A +++++ K + EVR+M PP VKL +E++C++ G
Sbjct: 3275 QMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTD 3334
Query: 2966 VPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQP-YIDNEEFQPA 3024
W+ + ++ +F+ ++ F + I D + + ++ Y+ N +
Sbjct: 3335 -------------WKQIRSIIMRE-NFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYE 3380
Query: 3025 TIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREV 3084
+ + S AC + +W A Y + K VEP R L + +DD Q+ +E +Q +R++
Sbjct: 3381 IVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDL 3440
Query: 3085 EDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQETVENLQYML 3144
E IA + +Y I++ + ++ E ++ R+ L+ LS E+ RW++T E + +
Sbjct: 3441 EASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQM 3500
Query: 3145 NNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQLRSHNVPHTSEPTLIGTLGNPVKIR 3204
+ I+GD L++A F+AY G F Q R L+ +W L+ N+ ++ L N +
Sbjct: 3501 STIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERL 3560
Query: 3205 SWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGLDVFKLSDRDFL 3264
WQ + LP D L EN ++ + R+ IDP QA ++I N KD + D F
Sbjct: 3561 RWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFR 3620
Query: 3265 RSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYI 3324
+++E+A+RFG P L+++V E DP L PVL ++ + G ++ LGD I F +++
Sbjct: 3621 KNLESALRFGNPLLVQDV-ESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFL 3679
Query: 3325 TTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLIISNAKMR 3384
+T+ P + P++ +++T +NFT++ S L+ Q L +V+ ERPD++E ++ L+ + +
Sbjct: 3680 STRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQ 3739
Query: 3385 QELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTRM 3444
L+ +E +L L+ +G +DD +I LE K +AAE+ KV + ++++
Sbjct: 3740 LRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQ 3799
Query: 3445 EYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIF---LSGIANSERADNLKKRISNI 3501
+Y+P++ ++F + L + +YQYSL++FL+I+ L N + + +R+S I
Sbjct: 3800 QYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSII 3859
Query: 3502 NRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQ----SEWRYLLSGGSISIM 3557
+ L ++ V R + + + FA LL RI + +G + + +E+++ L G I +
Sbjct: 3860 TKDLFQVAFNRVARGMLHQDHITFAMLL-ARIKL-KGTVGEPTYDAEFQHFLRGNEIVLS 3917
Query: 3558 T-ENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHREPLPGIWD 3616
P L+ ++ LS LP F + V+ +F + DS P + +P +W
Sbjct: 3918 AGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAK-VQADEQFGIWLDSSSP-EQTVPYLWS 3975
Query: 3617 QYL------DQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRF--IEPQTANLS-VVFKDS 3667
+ +LL+++ R D++ FV+TNL F I Q +L+ +V +
Sbjct: 3976 EETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEV 4035
Query: 3668 NSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQG-PRAEAMMRSSIERGKW 3726
TP++ PG D + + A E + ++++I++G +G +A+ + ++++ G+W
Sbjct: 4036 KPNTPVLMCSVPGYDASGHVEDLAAEQ--NTQITSIAIGSAEGFNQADKAINTAVKSGRW 4093
Query: 3727 VFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPP 3786
V +N HLAP W+ LE+ + + P H FRL+LT + K PV++L+ G EPP
Sbjct: 4094 VMLKNVHLAPGWLMQLEKKLHSLQP---HACFRLFLTMEINPKVPVNLLRAGRIFVFEPP 4150
Query: 3787 RGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFT 3846
GV+AN+L+++SS+ + C E L L FH ER ++ PLG++ YEF
Sbjct: 4151 PGVKANMLRTFSSIPVSRI--CKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFG 4208
Query: 3847 DGDLRICISQLKMFLDEY---------DDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNI 3897
+ DLR + +LD+ D IP+ LK + YGGRV +++D+R +
Sbjct: 4209 ESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTF 4268
Query: 3898 LEDFYNPDVLSPEHSYSASGIYH---QIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNAN 3954
LE + E + H Q+P ++ +++ LP P GL +NA
Sbjct: 4269 LERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAE 4328
Query: 3955 ITFAQNETFALLGTIIQLQ------------------PKSSSAGSQGREEIVEDVTQNIL 3996
+ ++ ++++Q S+S G + N L
Sbjct: 4329 RVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASNWL 4388
Query: 3997 LKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMS 4056
+P+ ++ + + ++ + +EV +LLQ + Q L D+++ +G +
Sbjct: 4389 HLIPQTLS---HLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQT 4445
Query: 4057 SQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQ----AWIQDGIPAV- 4111
+ L + L +P WS P+ + WV D +R+ LQ A G +
Sbjct: 4446 NYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELK 4505
Query: 4112 ---FWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQVGCYIHG 4168
+ G F P+A++T T Q A+ S++ + + V S+ + G
Sbjct: 4506 NIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNV---TTSQGATLDACSFGVTG 4562
Query: 4169 LFLEGARWDPEAFQLAESQPKEL-YTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGT 4227
L L+GA + L+ + L T++ W+ T K P+Y TRA
Sbjct: 4563 LKLQGATCNNNKLSLSNAISTALPLTQLR--WVKQTNTEK--KASVVTLPVYLNFTRADL 4618
Query: 4228 LSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALIC 4261
+ + + EI T + R + +RGVA++C
Sbjct: 4619 I--------FTVDFEIATKEDPRSFYERGVAVLC 4644
>gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]
Length = 4314
Score = 1233 bits (3189), Expect = 0.0
Identities = 970/3731 (25%), Positives = 1729/3731 (46%), Gaps = 322/3731 (8%)
Query: 657 PLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATHAVPQLEKLVMEDIFISGDPLL 716
P +DL + + P E+ A + I +P K V E +GD +
Sbjct: 773 PEINIDLTYKQGRLQFRPPFEEIRAKYYREMKRFI----GIPNQFKGVGE----AGDESI 824
Query: 717 ESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLA 776
S+ + L TI S L A ++++++ + D+ + ++ + L
Sbjct: 825 FSIMIDRNASGFL--TIFSKAEDLFRRLSAVLHQHKEWIVIGQVDMEALVEKH----LFT 878
Query: 777 QEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKKRKALATSVLDILAKNL 836
E L+ K LPS++ + IN + VK + L + D+L +L
Sbjct: 879 VHDWEKNFKALKIKGKEVERLPSAVKVDCLNINCNPVKTVIDD----LIQKLFDLLVLSL 934
Query: 837 HKEVDSICEEFRSISRKIYE----KPNSIEELAELREWMKGIPERLVGLEERIVKVMDDY 892
K + + E + + E P S+EE+ + + ER + I+ + +
Sbjct: 935 KKSIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSKLQER----KPEILPLFQEA 990
Query: 893 QVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQH---VEDEEKFRKIQIMDQNN- 948
+ + L ++ SN +K + EL+ + H ++D+ + K + +
Sbjct: 991 EDKNRLLRTVAGGGLET---ISNLKAK-WDKFELMMESHQLMIKDQIEVMKGNVKSRLQI 1046
Query: 949 FQEKLEGLQL----VVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQLAMLYNNRERI-- 1002
+ ++LE + + G + +E + + + + +K++ + L + R+++
Sbjct: 1047 YYQELEKFKARWDQLKPGDDV-IETGQHNTLDKSAKLIKEKKIEFDDLEV---TRKKLVD 1102
Query: 1003 ----FSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVV 1058
F L N+ S + K+ + +W ++ + + N+ + + +
Sbjct: 1103 DCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGFQEMANEDWITF---RTKTYLF 1159
Query: 1059 EAF-KTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQ 1117
E F H +++ ++ + + +++ ++++K IP+++ +R + HW L
Sbjct: 1160 EEFLMNWHDRLRKVEEHSV---MTVKLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFRL 1216
Query: 1118 ININVRPKAN----LTFARCLEMNLQDHIESISKVAEV------AGKEYAIEQALDKMEK 1167
+ + P+ L F L + D I ++K A++ A E I +AL +++
Sbjct: 1217 LGL---PRGTSLEKLLFGDLLRV--ADTI--VAKAADLKDLNSRAQGEVTIREALRELDL 1269
Query: 1168 EWSTILFNVLPYKATDTYILKSPDEASQLLD---DHIVMTQNMSFSPYKKPFEQRINSWE 1224
+F ++ Y+ + + +K + +++ D+ + Q++ SPY K FE +++ WE
Sbjct: 1270 WGVGAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWE 1329
Query: 1225 NKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYEN 1284
KL E L+ + QR W+YLEPIF LP E R+ ++ ++ IM + ++
Sbjct: 1330 RKLAELDEYLQNLNHIQRKWVYLEPIFG----RGALPKEQTRFNRVDEDFRSIMTDIKKD 1385
Query: 1285 REVINVCSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTK 1344
V + + + +SL L QK L+E+LE KRSAFPRFYF+ DD+LLEIL Q+
Sbjct: 1386 NRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQST 1445
Query: 1345 DPTAVQPHLRKCFENIARLLFQEDLE-ITHMYSAEGEEVQLCFSIYPSSNVEDWLREVER 1403
+P+ +Q HL+K F I + F E + IT M S EGE V + S+NVE WL ++
Sbjct: 1446 NPSVIQSHLKKLFAGINSVCFDEKSKHITAMKSLEGEVVPFKNKVPLSNNVETWLNDLAL 1505
Query: 1404 SMKASVHDIIEKAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLRSQLF 1463
MK ++ ++++ + + +P Q+ Q +T +V A++ +L Q+
Sbjct: 1506 EMKKTLEQLLKECVTTGRSSQGAVDPSLFPSQILCLAEQIKFTEDVENAIKDHSLH-QIE 1564
Query: 1464 PQLCQQLSDLVALVRGKL------SRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDF 1517
QL +L + S + L ALI+ +H DVV +L Q V + D+
Sbjct: 1565 TQLVNKLEQYTNIDTSSEDPGNTESGILELKLKALILDIIHNIDVVKQLNQIQVHTTEDW 1624
Query: 1518 QWISQLRYYW-TNNDLYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFG 1576
W QLR+Y +++ ++ V++EF Y YEY GN+ +LV TPLTD+CYLTLT A+ + G
Sbjct: 1625 AWKKQLRFYMKSDHTCCVQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLG 1684
Query: 1577 GAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFN 1636
G P GPAGTGKTE+ K LG L Q +VFNC + +D +MG+ F GL GAW CFDEFN
Sbjct: 1685 GNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFN 1744
Query: 1637 RIDIEVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNP---GYAGRTEL 1693
R++ VLS V+ QI TIQ A + G E+ + + +FITMNP GY GR +L
Sbjct: 1745 RLEESVLSAVSMQIQTIQDALKNHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKL 1804
Query: 1694 PDNLKALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDF 1753
PDNLK LFRPVAM PD +I E+ LYS GF +A VL++K+ F LS E L+ Q HYD+
Sbjct: 1805 PDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDW 1864
Query: 1754 GMRAVKTVISAAGNLKRE------NPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSD 1807
G+RA+KTV+ +GNL R+ + NE I ++A+R + KF D F ++ D
Sbjct: 1865 GLRALKTVLRGSGNLLRQLNKSGTTQNANESHIVVQALRLNTMSKFTFTDCTRFDALIKD 1924
Query: 1808 LFPTIKEEDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSG 1867
+FP I+ ++ +Y L A+++ +N + + + K ++LYE R G+++VGP+G+G
Sbjct: 1925 VFPGIELKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGAG 1984
Query: 1868 KSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIF 1927
KST +R+L AA+ + V Y +NPK++ QL G D+ T EW+DG+
Sbjct: 1985 KSTLWRMLRAALCKTG----------KVVKQYTMNPKAMPRYQLLGHIDMDTREWSDGVL 2034
Query: 1928 SSFIRAGAITSDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMF 1987
++ R W + DG +D WIE++N+VLDDN+ L + SGE I+ + +F
Sbjct: 2035 TNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVF 2094
Query: 1988 EVQDLAVASPATVSRCGMVYLEPSILGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEE 2047
E DL+ ASPAT+SR GM++L L I+ WLR P Y + + + E+
Sbjct: 2095 ETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQPA---EYRNNLENWIGDYFEK 2151
Query: 2048 SISFVRSSVKEVIASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWF 2107
++ +V V+ ++ M+ L L G + F
Sbjct: 2152 ALQWVLKQNDYVVETSLVGTVMNGLSHL----------HGCRDHDE-------------F 2188
Query: 2108 IFSLIWSVGATGDSSGRTSFS----HWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISGT 2163
I +LI +G + R F+ HW R + +
Sbjct: 2189 IINLIRGLGGNLNMKSRLEFTKEVFHWARESPPDFHKPM--------------------- 2227
Query: 2164 NDSEDEEEEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLD-----MLLT 2218
D+ + + +V P + D + +P + T M LD +
Sbjct: 2228 -DTYYDSTRGRLATYVL----KKPEDLTADDFSNGLTLPVIQTPDMQRGLDYFKPWLSSD 2282
Query: 2219 NKKPVLCIGPTGTGKTLTISDKLLKNLALDYISHFLTFSARTSANQTQDFIDSKLDK--- 2275
K+P + +GP G GK + L A + + SA T + KL +
Sbjct: 2283 TKQPFILVGPEGCGKGM------LLRYAFSQLRSTQIATVHCSAQTTSRHLLQKLSQTCM 2336
Query: 2276 ----RRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAF 2331
V+ P + ++ D+N+P L+ +G + L+Q + + G+YD + +
Sbjct: 2337 VISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDENL--EW 2394
Query: 2332 KNLVDINFVCAMGPPGG-GRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLL 2390
L +I V +M G GR+ +T R + + +D ++++ TI G +L+ +L
Sbjct: 2395 VGLENIQIVASMSAGGRLGRHKLTTRFT---SIVRLCSIDYPEREQL-QTIYGAYLEPVL 2450
Query: 2391 GEKSYRERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGM 2450
+ + G+ + L + + VY + ++ SHY F L++ G+
Sbjct: 2451 HKNLKNHSIWGSSSKIYL---LAGSMVQVYEQVRAKFT-VDDYSHYFFTPCILTQWVLGL 2506
Query: 2451 LMADPAKVEDQVQL---LRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCME-QW--EVTF 2504
D L L + +E R+FRD++V ++ FD +L + W ++
Sbjct: 2507 FRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWGSDILD 2566
Query: 2505 NKVCPFQPILYGDFMSPGSDVKSYELITSESK---------MMQVIEEYIEDYNQINTAK 2555
N F + +G + G+ + + K + VI++ + Y + N
Sbjct: 2567 NMSDSFY-VTWGARHNSGARAAPGQPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQ-N 2624
Query: 2556 LKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKN 2615
L ++LF + + ++ RI R L G+ LL G G GR ++T L SHM F ++S+
Sbjct: 2625 LDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRG 2684
Query: 2616 YGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQ 2675
Y + ++++D+K VL AG++ + L D Q + +FLE IN++L+SG++P LYT +E
Sbjct: 2685 YELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEEL 2744
Query: 2676 DQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVN 2735
+ ++ ++ + G N +T R++ N+H+VL M F P+L
Sbjct: 2745 EPLLLPLKDQASQDGFFGPVFNY---FTYRIQQNLHIVLIMDSANSNFMINCESNPALHK 2801
Query: 2736 CCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQ-----------GLIQVCVYIHQS 2784
C + W W ++K + + +E E ++ + ++ + IH+S
Sbjct: 2802 KCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHES 2861
Query: 2785 VSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSE 2844
C Y A TP Y+ LH++S + KK EL ++ +++G+ KL
Sbjct: 2862 ----CKAYGA--------TPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKA 2909
Query: 2845 DVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQA 2904
V ++ LL+ + ++ I V A E + ++ + + E+ K +
Sbjct: 2910 LVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEE 2969
Query: 2905 IADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPK 2964
+ +L E P ++ A ++ N+ ++E+R+++ PP ++ ++E V + GI
Sbjct: 2970 RKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGI--- 3026
Query: 2965 KVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQPYI--DNEEFQ 3022
D W K L G E + FD NI + ++++ + + F
Sbjct: 3027 ----------FDTSWVSMKSFLAKRG-VREDIATFDARNISKEIRESVEELLFKNKGSFD 3075
Query: 3023 PATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLR 3082
P + S A + WV+A +Y V + + P + +L T+ + ++ L
Sbjct: 3076 PKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLN 3135
Query: 3083 EVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQETVENLQY 3142
V ++ ++ K++ ++ +LE + + ++ + A LIN L E RW V +
Sbjct: 3136 SVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITE 3195
Query: 3143 MLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQLRSHNVPHTSEPTLIGTLGNPVK 3202
L + +AA F+ YL R + W K L L +
Sbjct: 3196 ELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWTKSAGLEKFD------LRRFLCTESE 3249
Query: 3203 IRSWQIAGLPNDTLSVENGVI-------NQFSQRWTHFIDPQSQANKWIKNMEKDNGLDV 3255
W+ GLP+D LS+EN ++ +S+ IDP SQA +W+K KD+ L+V
Sbjct: 3250 QLIWKSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRLEV 3309
Query: 3256 FKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIP 3315
D +F+ ++E A+RFGK +++ + + ++P L P+L + Q V+++GD +I
Sbjct: 3310 INQQDSNFITALELAVRFGKTLIIQEM-DGVEPVLYPLLRRDLVAQGPRYVVQIGDKIID 3368
Query: 3316 YHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQ 3375
Y+E+FR++++T+ PNP P+ ++ +T +NFT + SGL QLL + E+PDLEE K +
Sbjct: 3369 YNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTK 3428
Query: 3376 LIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQT 3435
L+ + +L +E+ +L L++S+GN +++ +LI+ L +K +A IQ ++ + +
Sbjct: 3429 LLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKL 3488
Query: 3436 EKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLK 3495
+ +D R Y+P+A ++F +SDL+ ++ MY++SL FL +F + N + ++N +
Sbjct: 3489 QISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTE 3548
Query: 3496 KRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRY-------- 3547
+RI ++ L + +Y +CR LF+ +LMFA L VR M E ++EW
Sbjct: 3549 QRIQSLISSLQHMVYEYICRCLFKADQLMFA-LHFVRGMHPE-LFQENEWDTFTGVVVGD 3606
Query: 3548 LLSGGSISIMTENPAPDWL-SDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEP 3606
+L + P W+ +R+W LP S + + + + +R +++
Sbjct: 3607 MLRKADSQQKIRDQLPSWIDQERSWAVATLKIALP--SLYQTLCFEDAALWRTYYNNSMC 3664
Query: 3607 HREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKD 3666
+E P I + + FQ++LV++ LR D++ +AM F L + + P NL ++K+
Sbjct: 3665 EQE-FPSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKE 3723
Query: 3667 SNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSSIERGKW 3726
+ P++ ++SPG DP+ +L + A + + +++GQGQ A M++ G W
Sbjct: 3724 TLEIEPILIIISPGADPSQELQELANAERSGECYHQVAMGQGQADLAIQMLKECARNGDW 3783
Query: 3727 VFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPP 3786
+ +N HL SW+P LE+ + + P FRLWLT+ F +LQ+ K+T E P
Sbjct: 3784 LCLKNLHLVVSWLPVLEKELNTLQPKDT---FRLWLTAEVHPNFTPILLQSSLKITYESP 3840
Query: 3787 RGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFT 3846
G++ NL+++Y S + ++ + L SL FH ERR + P G+ YEF+
Sbjct: 3841 PGLKKNLMRTYESWTPEQISKKDNTHRAHA-LFSLAWFHAACQERRNYIPQGWTKFYEFS 3899
Query: 3847 DGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDV 3906
DLR + + D D+ ++ + YGGR+ + +D R + + L+ F+N V
Sbjct: 3900 LSDLRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSV 3959
Query: 3907 LSPEHSYSASGIYH---QIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETF 3963
+ + + I+ +P + + Y + I+ +P +D P FGL N +Q
Sbjct: 3960 IDVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPANI-ARSSQRMIS 4018
Query: 3964 ALLGTIIQLQPKSSSAGSQGREEIVEDVTQ---NILLKVPEPINLQWVMAKYPVLYEESM 4020
+ + + +++ +S +AGS+ EI + N+ K+ + NL + K P +
Sbjct: 4019 SQVISQLRILGRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNL--IHQKVPPPNDRQG 4076
Query: 4021 NTVL---VQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSA 4077
+ +L + E RL+Q + Q+L L K ++G ++SS+++ +A++L N P W +
Sbjct: 4077 SPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQS 4136
Query: 4078 KAYPSLKPLSSWVMDLLQRLDFLQAWI-----QDGIPAVFWISGFFFPQAFLTGTLQNFA 4132
K PL ++ L+ R +Q W+ Q + +S F P FL Q A
Sbjct: 4137 KWEGPEDPL-QYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETA 4195
Query: 4133 RKFVISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELY 4192
R S+D++ F + Q ++ I GL LEG +D QL+E+Q
Sbjct: 4196 RAVGRSVDSLKF-----VASWKGRLQEAKLQIKISGLLLEGCSFDGN--QLSENQLDSPS 4248
Query: 4193 TEMAVI----WLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQP 4248
+ W+ + P+Y T+ V +++P
Sbjct: 4249 VSSVLPCFMGWIPQDACGPYSPDECISLPVY----------TSAERDRVVTNIDVPCGGN 4298
Query: 4249 QRHWIKRGVAL 4259
Q WI+ G AL
Sbjct: 4299 QDQWIQCGAAL 4309
>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
sapiens]
Length = 4515
Score = 975 bits (2520), Expect = 0.0
Identities = 587/1884 (31%), Positives = 976/1884 (51%), Gaps = 221/1884 (11%)
Query: 2573 RTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKA 2632
R L + L N +G+ G G+ + LA ++ + + +++ +S E+++ KKV + A
Sbjct: 2653 RLLSRELENCFQIGIDGCGKKTCATLACYLTDNKLYRVPISHKCAYIEFKEVFKKVFIHA 2712
Query: 2633 GLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQ 2692
GL+ P + + I+ +SFLED+N +++SG IP+L+ E D I +R ++ G
Sbjct: 2713 GLKGKPTVLMVPNLNIEQDSFLEDLNYIISSGRIPDLFENVELDSIAMKIRYLTEQSGHM 2772
Query: 2693 PTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKS 2752
+ +L++ + R+ N+H+ + MSP G FR R +PS+++ CTIDW+ WP EAL
Sbjct: 2773 DNRQSLLSFFQKRIYKNLHIFVIMSPEGPSFRQNCRVYPSMISSCTIDWYERWPEEALLI 2832
Query: 2753 VATVFLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLH 2812
VA FL E E+ + + L CV IH+S+ +Y E R Y TP SYL+ +
Sbjct: 2833 VANSFLKEKVNFENRENLKEKLAPTCVQIHKSMKDLNRKYFEETGRFYYTTPNSYLQFME 2892
Query: 2813 IFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTME 2872
F+ ++ ++ E++T ++R GL +L + V +MQE+L + P +E+ K+T ME
Sbjct: 2893 TFAHILRAREEEMQTKRDRFHMGLSTILEATTLVTEMQEELLILGPQVEQKTKETETLME 2952
Query: 2873 QIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNK 2932
+++ D+ + E+ + V+ +E E+ + + A +L LPA D A+ +L L+K
Sbjct: 2953 KLRKDSQVVEKVQMLVKQDEEIVAEEVRIVEDYAQKTANELKSVLPAFDKAIVALNALDK 3012
Query: 2933 NDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHF 2992
DV E+R RPP V V+ AVCI+ KP W K LL + G F
Sbjct: 3013 ADVAELRVYTRPPFLVLTVMNAVCILLQKKPN--------------WATAKLLLSETG-F 3057
Query: 2993 LESLFKFDKDNIGDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKA 3052
L+ L DKD+I D V ++ + +F P I+ VS AC S+CQWV A++ YH V K
Sbjct: 3058 LKKLINLDKDSIPDKVFVKLKKIVTLPDFNPHKISLVSVACCSLCQWVIALNNYHEVQKV 3117
Query: 3053 VEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQC 3112
V PK+ + EAQ+ L + ++ L E ++ L+ VE+ + +QA Y++ + +K+ L +
Sbjct: 3118 VGPKQIQVAEAQNVLKIARQRLAEKQRGLQLVEEHLLFLQAAYKDTVAEKQLLANRKTMA 3177
Query: 3113 EQRLGRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVL 3172
+R A L+ L DEK RWQET+ + L I GD+L++A + Y G T ++R ++
Sbjct: 3178 SRRFQCASVLLTVLEDEKTRWQETINQIDNKLEGILGDILLSAACIVYSGILTPEFRQLI 3237
Query: 3173 YDSWVKQLRSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTH 3232
+ W + + +S+ +LI + +I W GLP+ SVEN ++ + Q+W
Sbjct: 3238 VNKWETFCIENGISLSSKFSLIKVMAQKYEISRWHNQGLPHGQYSVENAILIKNGQQWPL 3297
Query: 3233 FIDPQSQANKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEP 3292
IDP QA+KWI+ ME + L + D ++ + +ENA++ G LL+N+ E L P L+
Sbjct: 3298 LIDPHRQAHKWIRQME-GSRLQKLSIEDSNYTKKIENAMKTGGSVLLQNLLETLAPGLKA 3356
Query: 3293 VLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSG 3352
+L K Y+++G+ +++GD Y+ +FR+Y++T++ NPH+ P + +T+INFT++ G
Sbjct: 3357 ILKKDIYQKKGHYFIRVGDAEFEYNSNFRLYLSTEIDNPHFLPSVYNFVTMINFTVTFQG 3416
Query: 3353 LEDQLLGQVVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELI 3412
L+DQLL VV E P LE+ +++L+ S + L+++E++ L L + G+ +DD +++
Sbjct: 3417 LQDQLLSTVVTHEVPHLEDQRSKLLESISLDAITLEELEEKTLNLLQKALGSILDDDKIV 3476
Query: 3413 KVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQY 3472
L SKM + EI ++ ++ E +I R Y+P+A R +L+F V+DL ++ MYQ+
Sbjct: 3477 DTLRKSKMTSNEISKRIEATKKAESEIQAIRKNYLPIATRGALLYFLVADLTQINYMYQF 3536
Query: 3473 SLEWFLNIFLSGIANSERADN-------------------------------LKKRISNI 3501
SL+WF +F+S + + + L K I +
Sbjct: 3537 SLDWFHQVFVSSVVSKSKEQEHSFKREKVSPKEVHEFISISKEPNLENEKNLLDKHIKSA 3596
Query: 3502 NRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNE----------GKINQSEWR-YLLS 3550
LT S++ V +LF + KL F+F LC IM N G + + EW +L S
Sbjct: 3597 IDMLTKSIFKVVSSALFNEDKLCFSFRLCTVIMQNNANGNLIQDDIGFLPEEEWNIFLYS 3656
Query: 3551 GGSISIMT--------------ENPAPDWLSDRAWRDILALS-NLPTFSSFSSDFVKHLS 3595
G I+I + E+ WLSD WR +S +L FS + ++S
Sbjct: 3657 GILINIKSALSQSRLTSTFEIGESQHLQWLSDSRWRQCQYVSTHLEPFSLLCKSLLSNVS 3716
Query: 3596 EFRVIFDS------------------------------LEPHRE---PLPGIWDQYLDQF 3622
++ +S L ++E P+ W++ L F
Sbjct: 3717 QWDTFKNSKAVYSLISTPFSSENASLEENTKPPEETELLNENKETCNPINFPWEK-LTSF 3775
Query: 3623 QKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTPLIFVLSPGTD 3682
Q+L++++ LR + + N+++ F+ + ++++ NL +K SN+ TPLI + + G D
Sbjct: 3776 QRLILVKVLRPESLNNSVRKFITEKMGNKYLQRTGVNLKDAYKGSNARTPLILIQTHGID 3835
Query: 3683 PAADLYKFAEEMK-FSKKLSAISLGQGQGPRAEAMMRSSIER-GKWVFFQNCHLAPSWMP 3740
L +FA+E+K + ++ ISLG+ Q +AE ++ ++ + +WVF QNCHLA S+MP
Sbjct: 3836 LTNILLRFAQELKGTTHHVTIISLGRDQAAKAEDLILKALTKTQQWVFLQNCHLATSFMP 3895
Query: 3741 ALERLIEHINPDKVHRD--FRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVRANLLKSYS 3798
L ++E N V D FRLWL+S + FP+ +L+ G K+ +E P+G+++NLL+++
Sbjct: 3896 RLCTIVESFNSPNVTIDPEFRLWLSSKSYSSFPIPVLKKGLKIAVESPQGLKSNLLQTFG 3955
Query: 3799 SLG-----EDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRIC 3853
G E+ + +K LL SLC F+ ER+ +G LG+NI Y+F DL +
Sbjct: 3956 CTGSGEVTEEIFENPDCGQWWKKLLFSLCFFNAVINERKNYGILGWNIAYKFNSSDLGVA 4015
Query: 3854 ISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSPEHSY 3913
I L+ L I ++ L+Y GE+ YGGRV D+WD+RC+ +L F NP+VL + S+
Sbjct: 4016 IKVLENSLRGQPSISWQALRYLIGEVIYGGRVIDNWDKRCLKTLLYKFCNPEVLKDDFSF 4075
Query: 3914 SASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQ 3973
S S + Y+ I+SLP +D+PE+ G+H A + + + + +I +Q
Sbjct: 4076 SRSA---------SIKDYIHIIQSLPDDDLPEVLGIHPEAIRSCWETQGEKFIENLIAMQ 4126
Query: 3974 PKSSSAG-----SQGREEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEESMN------- 4021
PK+++A Q ++E+V ++ ++L ++P + + + P + M+
Sbjct: 4127 PKTTTANLMIRPEQSKDELVMEILSDLLKRLPLTVEKEEIAVGTPSTLKSMMSSSIWESL 4186
Query: 4022 ----------------TVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAAS 4065
T L QE+ R+++LL VI ++L+DL A+KG ++++ +LE + S
Sbjct: 4187 SKNLKDHDPLIHCVLLTFLKQEIKRFDKLLFVIHKSLKDLQLAIKGEIILTQELEEIFNS 4246
Query: 4066 LYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQ-------------------- 4105
N VP LW AY S KPLSSW+ DL+QRL+F W +
Sbjct: 4247 FLNMRVPTLWQKHAYRSCKPLSSWIDDLIQRLNFFNTWAKVAYTAIQRRYMRFVTVWKQS 4306
Query: 4106 -------------------DGIPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISF-- 4144
+G P+ +W+ FFFPQAFL LQ++ R I++D ++F
Sbjct: 4307 IPSTSQKCKHPEDSENNFFEGFPSRYWLPAFFFPQAFLAAVLQDYGRSRGIAVDALTFTH 4366
Query: 4145 ---------DFKVMFEAPSEL---------TQRPQVGCYIHGLFLEGARWDPEAFQLAES 4186
D K P +L + G YI GLF+EGARW+ E L +S
Sbjct: 4367 HVISNTTDKDEKFSVFMPKKLNIVRRAFKGSASSHTGVYIFGLFIEGARWNREQKILEDS 4426
Query: 4187 QPKELYTEMAVIWLLP------TPNRKAQ-DQDFYL--CPIYKTLTRAGTLSTTGHSTNY 4237
P E+ + I+ LP TPN Q D + Y CP+Y+T R+ L+TTG TN+
Sbjct: 4427 LPLEMCCDFPDIYFLPTKISTKTPNASNQTDSELYAFECPVYQTPERSRILATTGLPTNF 4486
Query: 4238 VIAVEIPTHQPQRHWIKRGVALIC 4261
+ +V + T +P HWI VAL+C
Sbjct: 4487 LTSVYLSTKKPPSHWITMRVALLC 4510
Score = 762 bits (1968), Expect = 0.0
Identities = 491/1464 (33%), Positives = 763/1464 (52%), Gaps = 129/1464 (8%)
Query: 723 EPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLAQEVREV 782
+P + + + + + +M + AY+ ++ KY + +K + G L + E
Sbjct: 687 DPAYQNIIVNLLTIIGNSMGLVNAYSHKFIKYCTMTEKAKIMSMKI-SSMGELTSKEFEA 745
Query: 783 VLTHLRE--KEILDSSLPSSIII---------GPFYINTDNVKQSLSKKRKALATSVLDI 831
+L R + I++ ++ I I + DNV L SV++
Sbjct: 746 ILNRFRNYFRHIVNMAIEKRIGIFNVVSLDYQSECLLYIDNVIHM----SHTLIQSVIEK 801
Query: 832 LAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLVGLEERIVKVMDD 891
KNL + V+S ++ P IEE E ++ I ++ LE+ + +
Sbjct: 802 KNKNLLEVVESSLQQLEC-------DPTEIEEFLEHFIFLNAISSKISKLEKEFLTMSQL 854
Query: 892 YQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFR-KIQI------M 944
Y V ++S + + S++ ++L + KFR ++ +
Sbjct: 855 YSVAKHHQIHISEEQIAIFQVLLLKFSQLKSSMKLSKINKDTAITKFRDNLEACISGLHV 914
Query: 945 DQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLK------DCQQLAMLYNN 998
D N + K+ L+ AG + + ++ E + + K DC + + +
Sbjct: 915 DVGNLKAKIRTPLLLCAGTQVSTAMEMIQTLSGEAASLTNKAKAYSHYQDCFSDSQSHMH 974
Query: 999 RERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVV 1058
+ + ++S + + LW +W R S W N L +ID E +++NV
Sbjct: 975 SVNVEEITQIVLSEISDIEGDLTLRKKLWEAQEEWKRASWEWRNSSLQSIDVESVQRNVS 1034
Query: 1059 EAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQI 1118
K MH K +P ++ ++ + EFK +P+I L NP ++ RHWE L I
Sbjct: 1035 ---KLMHIISVLEKGLPK-SDMVTHLKQVVTEFKQELPIIIALGNPCLKPRHWEALQEII 1090
Query: 1119 NINVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLP 1178
+V N L + + + I+ ++ A E A+E+ L K+ W+T ++
Sbjct: 1091 GKSVPLDKNCKVENLLALKMFQYENEINDMSTSATNEAALEKMLFKIIDFWNTTPLPLIL 1150
Query: 1179 YKAT--DTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEE 1236
+ +I+ S D+ S L++ V+ + SP+ P + +N W+ L L LEE
Sbjct: 1151 HHTEIYSIFIIPSIDDISAQLEESQVILATIKGSPHIGPIKDLVNEWDQNLTLFSYTLEE 1210
Query: 1237 WLNCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRM 1296
W+NCQR+WLYLEP+F S +I +QLP E++ + + +WKKIM + + + + +
Sbjct: 1211 WMNCQRNWLYLEPVFHSSEIRRQLPAETELFSQVISMWKKIMSKIQNKQNALQITTSAGV 1270
Query: 1297 LDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKC 1356
L+ L++CN L+ ++K L +YLE KR FPRFYFLS+ ELL+IL+ +++P +VQPHL KC
Sbjct: 1271 LEILQNCNIHLEHIKKSLEDYLEVKRLIFPRFYFLSNAELLDILADSRNPESVQPHLVKC 1330
Query: 1357 FENIARLL-FQEDL---EITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDI 1412
FENI +LL +++D+ + + SAEGE + L I S VE WL VE+SM D+
Sbjct: 1331 FENIKQLLIWKQDIGPPAVKMLISAEGEGLVLPKKIRVRSAVEQWLVNVEKSM----FDV 1386
Query: 1413 IEKAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLRSQLFPQLCQQLSD 1472
++K Y + Q + + + +Y + E E + AG L L ++++D
Sbjct: 1387 LKKERYIYNIILLFQSQIMFYNDCVKSFVSSY-SREKLEKVHAG-LMCHL-----EEVAD 1439
Query: 1473 LVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNND- 1531
LV L + +A+L AL+++ VH +D+V L+ +N+ + DF+W L+Y W
Sbjct: 1440 LVVLDTS--NSRTKAILGALLILYVHCRDIVINLLLKNIFNAEDFEWTRHLQYKWNEKQK 1497
Query: 1532 -LYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTET 1590
Y+ NA F YGYEYLG + RLVITPLTDRC+LTL ALHL GG PAGPAGTGKTET
Sbjct: 1498 LCYVSQGNASFTYGYEYLGCTSRLVITPLTDRCWLTLMEALHLNLGGCPAGPAGTGKTET 1557
Query: 1591 TKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQI 1650
KDL K+L VVFNC + LD+ + KFF GL +GAW+CFDEFN ID+EVLSV+A QI
Sbjct: 1558 VKDLAKSLGKHCVVFNCFEDLDYKIVRKFFFGLVQSGAWSCFDEFNLIDLEVLSVIASQI 1617
Query: 1651 TTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPD 1710
TI+ A+ RF+ EG EI + SCAVFITMNP Y G ELPDNLK+LFRPVAMMVP
Sbjct: 1618 LTIKAAKDNYSARFVLEGKEIRINMSCAVFITMNPRYGGGVELPDNLKSLFRPVAMMVPH 1677
Query: 1711 YAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKR 1770
Y MI EI L+SFGF A+ L+ K+T ++L+ +QLS QDHY+FG+R++K V+ AG KR
Sbjct: 1678 YQMIAEIILFSFGFKSANSLSGKLTNLYELARKQLSQQDHYNFGLRSLKIVLIMAGTKKR 1737
Query: 1771 ENPSM---NEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIR 1827
E + +E LI + AIR+ ++PK ED+ LF I+ D+FP + + L++ I
Sbjct: 1738 EFKCLSEADETLIVIEAIREASLPKCPPEDVPLFENIIGDIFPEVTVLKVNQLALEKVIY 1797
Query: 1828 EACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPS 1887
A + L++ K IQ Y V G+MLVGPTG GK+T R+L A+T L
Sbjct: 1798 TATQQLGLQNWSSQKEKIIQFYNQLQVCVGVMLVGPTGGGKTTVRRILEKALTLLPIADF 1857
Query: 1888 ISGGMYEA----------VNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAI- 1936
+S ++ V+ VLNPK +T+ +LYG+ D T EWTDG+ S+ IR+
Sbjct: 1858 LSVAERKSASKISERKGKVDICVLNPKCVTLSELYGQLDPNTMEWTDGLLSATIRSYVYF 1917
Query: 1937 ----------------------------TSDTNK-----------------------KWY 1945
+SDT + +W
Sbjct: 1918 NTPKNTKKDIDLRLKSRISDLSNVFKLDSSDTTETDDNIFEEIEKVVKIPENHNFDWQWI 1977
Query: 1946 MFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGM 2005
+ DGPVD W+EN+N+VLDD + LCL++ E I LT + ++FEV +L+ ASPATVSRC M
Sbjct: 1978 ILDGPVDTFWVENLNSVLDDTRTLCLANSERIALTNKIRVIFEVDNLSQASPATVSRCAM 2037
Query: 2006 VYLEPSILGLMPFIECWLRKLPPLL-KPYEEHFKALFVSFLEESISFVRSSVK-EVIAST 2063
VY++P LG P+++ WL K ++ + + + + + + + + F+R+ K +
Sbjct: 2038 VYMDPVDLGWEPYVKSWLLKTSKIISQSGVDCLEFMIKNSVTDGLQFIRNRQKFQPYPME 2097
Query: 2064 NCNLTMSLLKLLDCFFKPFLPREG 2087
+ + ++L ++LD FF F+ + G
Sbjct: 2098 DITVVITLCRILDAFF-DFMGKNG 2120
Score = 152 bits (383), Expect = 9e-36
Identities = 92/260 (35%), Positives = 135/260 (51%), Gaps = 15/260 (5%)
Query: 2240 KLLKNLA-LDYISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNM 2298
KLLKN + + FS +A +T++ I KL +R K G P + FIDD+NM
Sbjct: 2415 KLLKNNDHKGVVVSTINFSTNVTAAKTKEMILKKLIRRTKDTLGAPKNNRILIFIDDMNM 2474
Query: 2299 PALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLM 2358
P + YGAQPP+EL+RQ +D GG YD + +KN+ D++ V A P N ++PRL+
Sbjct: 2475 PVSDMYGAQPPLELIRQLLDLGGVYDTE-KNTWKNIQDLSIVAACVPV---VNDISPRLL 2530
Query: 2359 RHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIM 2418
+HF+ L + IF LG Y P + + ++ ++
Sbjct: 2531 KHFSMLVLPHPSQDILCTIFQAHLG----------IYFSINNFTPEVQKSKDQIISCSLA 2580
Query: 2419 VYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRD 2478
+Y + +LPTP K HY FNLRD+ K+ G+L AD V + L+ HE RVF D
Sbjct: 2581 IYHQVRQNMLPTPTKCHYMFNLRDMFKLLLGLLQADRTVVNSKEMAALLFVHEATRVFHD 2640
Query: 2479 RLVNEEDRSWFDQLLKRCME 2498
RL++ D+S F +LL R +E
Sbjct: 2641 RLIDFTDKSLFYRLLSRELE 2660
Score = 40.4 bits (93), Expect = 0.038
Identities = 22/60 (36%), Positives = 29/60 (48%)
Query: 2184 SSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDKLLK 2243
S F + + C T DT +S L+ +LL N PVL G +G GKT I+ L K
Sbjct: 2293 SGGNFLKITECGECINYTATRDTTCLSFLMSLLLKNSCPVLLTGESGVGKTAAINQMLEK 2352
>gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sapiens]
Length = 798
Score = 481 bits (1238), Expect = e-135
Identities = 282/816 (34%), Positives = 446/816 (54%), Gaps = 36/816 (4%)
Query: 3460 VSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFE 3519
++DL+ + PMYQ+SL+ F +F + + ++L++R++N+ +T+S+Y R LFE
Sbjct: 1 MNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFE 60
Query: 3520 KHKLMFAFLLCVRIMMNEGKINQSEWRYLLSGGSISIMTENPAP-DWLSDRAWRDILALS 3578
KL + L +I++ ++N E +LL + T +P ++LS +AW + LS
Sbjct: 61 CDKLTYLAQLTFQILLMNREVNAVELDFLLRS---PVQTGTASPVEFLSHQAWGAVKVLS 117
Query: 3579 NLPTFSSFSSDFVKHLSEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTN 3638
++ FS+ D ++ +S P +E LP W Q+L +LR +R D++T
Sbjct: 118 SMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKT-ALQRLCMLRAMRPDRMTY 176
Query: 3639 AMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKFS- 3697
A++DFV L +++ + + + F++S TP+ F+LSPG DP D+ ++ ++
Sbjct: 177 ALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTF 236
Query: 3698 --KKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVH 3755
+ +SLGQGQ AEA + + ++G WV QN HL W+ LE+ +E + + H
Sbjct: 237 NNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEE-HSENSH 295
Query: 3756 RDFRLWLTSLPSNK-----FPVSILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHK 3810
+FR+++++ P+ P IL+N K+T EPP G+ ANL K+ + +D L C +
Sbjct: 296 PEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSR 355
Query: 3811 VMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYK 3870
EFKS+L +LC FH ERRKFGP G+N Y F GDL I ++ L FL+ +PY
Sbjct: 356 ETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYD 415
Query: 3871 VLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHG 3930
L+Y GEI YGG +TDDWDRR L +F P++L E S + +P D +G
Sbjct: 416 DLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPG---FPLPGNMDYNG 472
Query: 3931 YLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSA---GSQGREEI 3987
Y YI + + P ++GLH NA I F + L T+++LQP+ S A REE
Sbjct: 473 YHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEK 532
Query: 3988 VEDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLV--QEVIRYNRLLQVITQTLQDL 4045
V+ + + IL +V + N+ +MAK EE ++V QE R N L + I ++L++L
Sbjct: 533 VKALLEEILERVTDEFNIPELMAK----VEERTPYIVVAFQECGRMNILTREIQRSLREL 588
Query: 4046 LKALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQ 4105
LKG + M+S +E + +LY + VPE W+ +AYPS L++W DLL R+ L+AW
Sbjct: 589 ELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTG 648
Query: 4106 D-GIPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQVGC 4164
D +P+ W++GFF PQ+FLT +Q+ ARK +D ++ + + E P+ G
Sbjct: 649 DFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGA 708
Query: 4165 YIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTR 4224
YIHGLF+EGA WD +A + E++ K+L M V+++ P K + Y CP+YKT R
Sbjct: 709 YIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQR 768
Query: 4225 AGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALI 4260
T YV + T + W+ GVAL+
Sbjct: 769 GPT---------YVWTFNLKTKENPSKWVLAGVALL 795
>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
Length = 4753
Score = 214 bits (545), Expect = 1e-54
Identities = 254/1199 (21%), Positives = 475/1199 (39%), Gaps = 182/1199 (15%)
Query: 970 SRAHEIANEVRRVKKQLKDCQQLAMLY---NNRERIFSLPITNYDKLSRMVKEFQPYLDL 1026
S H++ + R+ + + D +L Y E LPI + + + + Y +
Sbjct: 969 STEHQLVSLERQFQNTVSDLSELHHAYAIFTEDETPVPLPICGTRPIVQQQRIWHLYRVI 1028
Query: 1027 WTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRA 1086
S+W + + + A+ E+ E + EA + + C +
Sbjct: 1029 SENISEWKCMAFAKFSP---AMAQEKTEGWLTEAARMSTTLELHSPVLQHCMRI------ 1079
Query: 1087 RIEEFKPYIPLIQGLRNPGMRIRHWETLSNQINI-NVRPKANLTFARCLEMNLQDHIESI 1145
+ EF+ Y+PL+ L + + + + L + + +++ LT + L L + + I
Sbjct: 1080 -LGEFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRI 1138
Query: 1146 SKVAEVAGKEYAIEQALDKMEKEWSTILFNVL------PYKA-----TDTYILKSP---- 1190
++V + + ++ + ++++ W +L PY+ + +L+SP
Sbjct: 1139 NQVWQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEV 1198
Query: 1191 ---DEASQLLDDHIVMTQNM--SFSPYKKPFEQRINSWENKLKLTQ--------EVLEEW 1237
D + +L D+ + ++ S K + NK+ L +LE W
Sbjct: 1199 VDKDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVW 1258
Query: 1238 LNCQRSWLYLEPI-------FSSEDINQQLPVESKRYQTMERIW---KKIMKNAYENREV 1287
L Q+ W++L + F + D+N + V +Y+T+ RI ++ + E
Sbjct: 1259 LTFQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAER 1318
Query: 1288 INVCSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPT 1347
++ L+ + L+ + L L + FPR +FLSD EL+ +L+ +
Sbjct: 1319 SPYFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESC 1378
Query: 1348 AVQPHLRKCFENIARLLF-------------------QEDLEITHMYSAEGEEVQLCFSI 1388
Q +R+CF ++ + F Q +E + A GEEV+L +
Sbjct: 1379 EAQLWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPL 1438
Query: 1389 YPSSNVEDWLREVERSMKASVHDIIEKAI-----------RAYPTMPRTQ------WVLN 1431
++ WL +E+ ++ ++ +++ + A +P+ +V +
Sbjct: 1439 PLHPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQH 1498
Query: 1432 W-------PGQVTIAGCQTYWTMEVAEAL-EAGNLRSQLFPQLCQQLSDLVALVRGKLSR 1483
W P Q + + W E+ EAL E G L + ++L LV +R + +
Sbjct: 1499 WIDLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLA--MVSMHMRKLEVLVNFMRAQRAS 1556
Query: 1484 M---------QRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNNDL-- 1532
Q ++LSAL+V+ V +D+ L Q V + DF W+ QL+Y+ + +
Sbjct: 1557 QGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIP 1616
Query: 1533 ----------------------YIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGA 1570
+I + F+Y YEYLG + + L +R L L A
Sbjct: 1617 KSPLQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLGPRLGPLPSLLPERPALVLLLA 1676
Query: 1571 LHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWA 1630
L G GP G GK L +AL Q V+ CS Q++ + + G GAW
Sbjct: 1677 LEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWL 1736
Query: 1631 CFDEFNRIDIEVLSVVAQQI------------------TTIQKAQQQRVERFMFE--GVE 1670
++ +++ +LS + Q++ +TI Q Q + FE V
Sbjct: 1737 LLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVS 1796
Query: 1671 IPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLYSFGFNEASVL 1730
+ L C + + A + +P NL L RPVA+ +PD + E++L G +A +
Sbjct: 1797 VRLGYGCLLVLR-----ALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQM 1851
Query: 1731 AKKITTTFKLSSEQLSSQDHYDFGMRAVKTVIS---AAGNLKRENPSMNE--ELICLRAI 1785
A +++ F L E +S + +K ++ N+ +E P + L +
Sbjct: 1852 ATRLSKFFSLERELVSGP--LPCRLPLLKQILEDTIRTLNVTKEEPKCQKPRSLAAIEEA 1909
Query: 1786 RDVNVPKF-LQEDLKLFS--GIVSDLFPTIKE---EDTDYGILDEAIREACRNSNLKDVE 1839
+ P F + L L + G++ LFP+ + E Y ++ + E + L
Sbjct: 1910 ALLRSPLFSILNGLHLHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSP 1969
Query: 1840 GFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYY 1899
L QL + G++L+GP GSGK+TC+ L L S + V
Sbjct: 1970 DILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEIT 2029
Query: 1900 VLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKK-----------WYMFD 1948
L P ++ + G + W GIF +RA ++ +K W + D
Sbjct: 2030 HLYPSGLSPQEFLGWLE--GSCWHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICD 2087
Query: 1949 GPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVY 2007
G + W++++ +L + +L L SG+ I ++ EV D SP V C +V+
Sbjct: 2088 GASNGAWLDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVW 2146
Score = 154 bits (388), Expect = 2e-36
Identities = 240/1124 (21%), Positives = 422/1124 (37%), Gaps = 161/1124 (14%)
Query: 3253 LDVFKLSDRDFLRSMENAIRFGKPCLLENVG-----EELDPALEPVLLKQTYKQQGNTVL 3307
L V +D + ++ A G P LL NV EEL L+ L Q G
Sbjct: 3664 LSVLSGADPELGSQLQEAAACGLPVLLTNVELGLGCEELQWLLQREQLSPPQVQPG---- 3719
Query: 3308 KLGDTVIPYHEDFRMYITTKLP----NPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVA 3363
F +Y++T L E+ L +++ L+ LE+Q+L +++
Sbjct: 3720 ------------FCLYLSTTLSLCAMEKVLGCELLKGLNVLDLGLNMEILEEQMLHEILC 3767
Query: 3364 EERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAA 3423
E P+LE L I + ++ E+++L L + ++ + ++ K
Sbjct: 3768 REYPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQNPKRQKPAKFLRNIVRAQGKLC 3827
Query: 3424 EIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLS 3483
+++A E + + Y PV + +S L N+ P++ S E +L +
Sbjct: 3828 QLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVTKQ 3887
Query: 3484 GIANSE-----RADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEG 3538
+ + + ++L + + +LT L + +L + L + ++ G
Sbjct: 3888 ALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQATG 3947
Query: 3539 KINQSEWRYLLSG--GSISIMTENPAPD-----WLSDRAWRDILALSNLPTFSSFSSDFV 3591
K ++ E L G S S + P D WL +AW + L LP F +
Sbjct: 3948 KASELERLALWPGLAASPSTVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLCASLA 4007
Query: 3592 KHLSEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPR 3651
H S ++ P PG + L QKL++ R LR + + A+ DF T+L R
Sbjct: 4008 GHSSAWQAYLSLSSTVLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADF-TTSLLGR 4066
Query: 3652 FIEPQTANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKF-------AEEMKFSKKLSAIS 3704
++ T ++ FK S +T P++ +L P P+A L+ A+ + K+L I+
Sbjct: 4067 PLDENTYAPTMPFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQLQVIA 4126
Query: 3705 LGQGQGPRAEAM---MRSSIERGKWVFFQNCHLAPSWMPALERLI--------------- 3746
LG + + ++ G W+ NCHL P W L +L+
Sbjct: 4127 LGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADLES 4186
Query: 3747 -------EHINPDKVHRDFRLWL--TSLPSNKFPVSILQNGSKMTIEPPRGVRANLLKSY 3797
E N VHRDFRLWL + S P + Q+ + + L+ S
Sbjct: 4187 EQLLDQPESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLELGHVLIDSV 4246
Query: 3798 SSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQL 3857
L + L M+ + L L L HG L R+ +G R L
Sbjct: 4247 -ELAQQVL-----YMQPPTQALPLLLLHGLLLHRQLYGT-------RLQAHRGRWSQVTL 4293
Query: 3858 KMFLDEYDDI------PYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSPEH 3911
L D + P ++ A + YGG + D DR ++++ + +P S
Sbjct: 4294 TQVLQTQDQLWASLSNPRAAMQELAASVFYGGPLGDTEDREALISLTQACLSPSSGSWVQ 4353
Query: 3912 SYSASGIYHQIPPTYDLHGY------LSYIKSLPLNDMPEIFGLHDNANITFAQNETFAL 3965
++ + + P +L + + LP P + GL + + ++ AL
Sbjct: 4354 PHTPQSLLATLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRAL 4413
Query: 3966 LGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEES------ 4019
L + + P +G ++ E + L++V + + + + +ES
Sbjct: 4414 LSALQRSSPVWVPESRRG-AQLAERRLRQRLVQVNRRLESLQDLLTHVIRQDESDAPWSV 4472
Query: 4020 --------MNTVLVQEVIRYNRLLQVITQTLQDLLKALKGL-VVMSSQLELMAASLYNNT 4070
+ VL E + ++L+ + + L LL+ LKG S + +A +L+
Sbjct: 4473 LGPNARRPLEGVLETEALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWTGR 4532
Query: 4071 VPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPA-------VFWISGFFFPQAF 4123
+P W A +P W+ L +R L ++ G A VF +S F P+
Sbjct: 4533 LPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPRRL 4592
Query: 4124 L---------------------TGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQV 4162
L G++ + + + +++ F+V P+ P+
Sbjct: 4593 LLALRGEAALDQNVPSSNFPGSRGSVSSQLQYKRLEMNSNPLHFRVE-NGPNPTV--PER 4649
Query: 4163 GCYIHGLFLEGARWDPEAFQLAES--------QPKELYTEMAVIWLLPTPNRKAQDQDFY 4214
G + GL + A WDP A L +S P + T+ LP P D Y
Sbjct: 4650 GLLLIGLQVLHAEWDPIAGALQDSPSSQPSPLPPVSISTQAPGTSDLPAP----ADLTVY 4705
Query: 4215 LCPIYKTLTRAGTLSTTG-HSTNYVIAVEIPTHQPQRHWIKRGV 4257
CP+Y G L T S N V+ + +PT ++R V
Sbjct: 4706 SCPVY----MGGPLGTAKLQSRNIVMHLPLPTKLTPNTCVQRRV 4745
Score = 94.4 bits (233), Expect = 2e-18
Identities = 140/670 (20%), Positives = 252/670 (37%), Gaps = 72/670 (10%)
Query: 2543 EYIEDYNQINTAKLKLVLFM----DAMSHICRISRTLRQALGNALLL-GVGGSGRSSLTR 2597
E +E+ + A+LKL + H+ R+ R L + + LLL G G+GR +
Sbjct: 2843 EKLEEQLATSAAQLKLSPHLARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAIT 2902
Query: 2598 LASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDI 2657
LAS + + F + + + D AG+ + P+ L + + L +
Sbjct: 2903 LASSICQAHFFHLPSGSEEAILQCLRDAS---WHAGMLSQPVALLVPSGV--DLTTLHRL 2957
Query: 2658 NNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCMS 2717
+ SG P YT + D+I + K ++ + +V S++H+
Sbjct: 2958 LALATSGSFPGQYTEADLDRIGEHLPRENLGVKQNIKKEMVLQRFHQQVCSHLHLFFL-- 3015
Query: 2718 PIGEVFRARLRQFPSLV-------NCCTIDWFNEWPAEALKSVATVFLN----------- 2759
IG+ + +Q PS + +ID + W AL VA L
Sbjct: 3016 -IGD--KQAHKQLPSTLFLRLLQLATASIDRYEPWDQAALAKVAQHHLEGAQSVPLDDGS 3072
Query: 2760 -EIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILI 2818
+ P+L++S I + + IH S + L VTPK++L+ L F +L
Sbjct: 3073 WKYPDLQAS---IPSVAKAMALIHLSATHYHEHLCPALP---LVTPKTFLDFLDTFLMLQ 3126
Query: 2819 GQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDT 2878
Q L++K R+++ L+ L ++ + + L+++ K + +Q++
Sbjct: 3127 QQTILKIKNKAQRVQNALENLRMLIKEHGTHANLIFDLEQQLKDSGKSLSMFQQQLEQSK 3186
Query: 2879 AIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEV 2938
+ ++ + +E A++ A+ + L++ A L L L D E+
Sbjct: 3187 LLYKQQLEECRHQENLIENLARQRDALQAQREAFLEQMSKAF---LEPLSQLQVADFEEI 3243
Query: 2939 RAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFK 2998
R+ + PP V V +A+C + + W K LL + E +F
Sbjct: 3244 RSYRAPPESVVRVTDAMCDL--------------FHHETGWASAKQLLCTEDFYQELVF- 3288
Query: 2999 FDKDNIGDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVA-------K 3051
F K+ I D + + + A + VS+ S+ W+ A+ Y
Sbjct: 3289 FPKEKITDSELIKLHLILKAPGMDDAALRAVSRPAASLAAWLWAVLHYGLAHCRGLPTDL 3348
Query: 3052 AVEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQ 3111
++ L Q LG Q E + + + QA + C+ K L Q
Sbjct: 3349 LLQQVEATLTREQARLGYYQFQAQETLEHNLALAKMVEDAQASHN-CVAKT----LSQAQ 3403
Query: 3112 CEQRLGRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTV 3171
C Q + L W ++ L+ + GD L+ + + YLGPF R
Sbjct: 3404 CGQY--HKWPMKAALLTPMRAWTTQLQKLKGRCMTVFGDTLLCSAAIIYLGPFPPLRRQE 3461
Query: 3172 LYDSWVKQLR 3181
L D W+ R
Sbjct: 3462 LLDEWLALCR 3471
Score = 77.4 bits (189), Expect = 3e-13
Identities = 96/427 (22%), Positives = 163/427 (38%), Gaps = 81/427 (18%)
Query: 2107 FIFSLIWSVGATGDSSGRTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDS 2166
F+F+LIW GA S F ++R + P LVFD +
Sbjct: 2287 FLFALIWGFGAHLPSRFWPIFDTFIRDSISRLSNYPEPPPSALVFDLHVSP--------- 2337
Query: 2167 EDEEEEYKQVAWV-KWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLC 2225
E+ V + +++ S T+ P++ T ++ +++D+LL+ +PVL
Sbjct: 2338 ----EDGTLVPFTGQYLSSHIKGTL-------GTFHPSIQTERLLYVVDLLLSGGQPVLL 2386
Query: 2226 IGPTGTGKTLTISDKLLKNLALDYI----------SHFLTFSARTSANQTQDFIDSKLDK 2275
G TGK+ + ++L YI SH +R QTQ +
Sbjct: 2387 AGEAATGKSAFV--EVLVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQ 2444
Query: 2276 RRKGVFGPPLGRNFIFFIDDLNMPALETY-GAQPPIELLRQWMDHGGWYDRKIIGAFKNL 2334
K + +F ++DL++ + QP +E LRQ MD G Y +
Sbjct: 2445 DSKP--------SLLFLLEDLHLATSDPEKSCQPVLETLRQAMD-GTVYAHSTLELQTLQ 2495
Query: 2335 VDINFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKS 2394
+NF+ + PG + PRL R F L+ M + + I+ WL
Sbjct: 2496 PTVNFLATVTVPGYCERPLCPRLFRLFTVLALESMTQATLLERHVPIIQAWL-------- 2547
Query: 2395 YRERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLM-- 2452
ER P LV A++ + + + +P+P HY F+L +S + + +
Sbjct: 2548 --ERFPSVERERALARGLVRASVEAWEAVCNCFMPSPLHPHYHFSLHSVSHLLSSLQLLP 2605
Query: 2453 --------ADPAKVEDQVQ------------------LLRLWYHENCRVFRDRLVNEEDR 2486
D ++ ++ ++RLW HE R F DRL + +R
Sbjct: 2606 NRTGSRGFVDYPNHQEHLRRVSGLRGTCLTVMMATRNVVRLWLHEAQRTFCDRLDSPRER 2665
Query: 2487 SWFDQLL 2493
S+ +LL
Sbjct: 2666 SYCAKLL 2672
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 46.6 bits (109), Expect = 5e-04
Identities = 62/315 (19%), Positives = 140/315 (44%), Gaps = 26/315 (8%)
Query: 2820 QKKLELKTAKNRMKSGLDKLLRT--SEDVAKMQEDLESMHPLLEEA-------AKDTMLT 2870
+KKL+ + + K LR +E +K+Q +L+++ LLEEA AKD
Sbjct: 1254 RKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASL 1313
Query: 2871 MEQIK-VDTAIAEETRNSVQ-TEEIKANEKAKKA----QAIADDAQKDLDEALPALDAAL 2924
Q++ + EETR + + I+ E+ K + Q ++A+K+L++ + AL + L
Sbjct: 1314 ESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQL 1373
Query: 2925 ASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKG 2984
A + +D+ + +++ KL+ +A + + ++ K + +K + +
Sbjct: 1374 ADTKKKVDDDLGTIESLEEAKK--KLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDD 1431
Query: 2985 LLQDPGHFLESLFKFDKDNIGDVVIKAIQPYI------DNEEFQPATIAKVSKACT---S 3035
L D H + +K + A + I + + + K +KA + +
Sbjct: 1432 LTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARA 1491
Query: 3036 ICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKY 3095
+ + + A ++ K + + L+ ++DD+G L+++K+ L + + + T +
Sbjct: 1492 LEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEEL 1551
Query: 3096 RECITKKEELELKCE 3110
+ + E+ +L+ E
Sbjct: 1552 EDELQATEDAKLRLE 1566
Score = 34.7 bits (78), Expect = 2.1
Identities = 54/270 (20%), Positives = 114/270 (42%), Gaps = 30/270 (11%)
Query: 2823 LELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAE 2882
L++ + +++ ++LL+ E K++ +LE M ++ ++ + EQ++ +T +
Sbjct: 845 LQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFA 904
Query: 2883 ETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQ 2942
E EE++A AKK ++L+E L L++ + N+ E + MQ
Sbjct: 905 E------AEEMRARLAAKK---------QELEEILHDLESRVEEEEERNQILQNEKKKMQ 949
Query: 2943 RPPPGVKLVI-EAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDK 3001
++ + E + ++ +KV E K+++ LL+D K +
Sbjct: 950 AHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEIL----LLEDQNSKFIKEKKLME 1005
Query: 3002 DNIGDVVIKAIQPYIDNEEFQPATIAKV-SKACTSICQWVRAMHKYHFVAKAVEPKRQAL 3060
D I + + EE + +AK+ +K I + K + +E ++ L
Sbjct: 1006 DRIAE-----CSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKL 1060
Query: 3061 ----LEAQDDLGVTQRILDEAKQRLREVED 3086
+ QD + Q +DE K +L + E+
Sbjct: 1061 DGETTDLQDQIAELQAQIDELKLQLAKKEE 1090
Score = 33.1 bits (74), Expect = 6.1
Identities = 19/93 (20%), Positives = 45/93 (48%), Gaps = 5/93 (5%)
Query: 2820 QKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTA 2879
+ K E + ++++ ++ L+ + +DV K +LE LE+ ++ +E+++ +
Sbjct: 1497 EAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQ 1556
Query: 2880 IAEETRNSVQTEEIKANEKAKKAQAIADDAQKD 2912
E+ + ++ N +A KAQ D +D
Sbjct: 1557 ATEDAK-----LRLEVNMQAMKAQFERDLQTRD 1584
>gi|7706353 vacuolar protein sorting 24 isoform 1 [Homo sapiens]
Length = 222
Score = 46.2 bits (108), Expect = 7e-04
Identities = 49/210 (23%), Positives = 96/210 (45%), Gaps = 27/210 (12%)
Query: 2743 NEWPAEALKSVATVFLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYV 2802
NEW + K + V +I +++ +E+++ ++ Q CI E+ R
Sbjct: 17 NEWSLKIRKEMRVVD-RQIRDIQREEEKVKRSVKDAAKKGQK--DVCIVLAKEMIRSRKA 73
Query: 2803 TPKSYLELLHIFSILIGQKK--LELKTAKNRMKS-----GLDKLLRTSEDVAKMQEDLES 2855
K Y H+ S+L+G K L+ A + KS + L++ E A M+E +
Sbjct: 74 VSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKE 133
Query: 2856 MHP--LLEEAAKDTMLTME---------QIKVDTAIAEETRNSVQTEEIKANEKAKK--- 2901
M ++EE +DT +M+ ++++D + E T ++ K + +
Sbjct: 134 MMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGKAPSKVTDALPEPEP 193
Query: 2902 --AQAIADDAQKDLDEALPALDAALASLRN 2929
A A ++D +++ +EAL A+ + LA+LR+
Sbjct: 194 PGAMAASEDEEEE-EEALEAMQSRLATLRS 222
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 43.9 bits (102), Expect = 0.003
Identities = 96/470 (20%), Positives = 193/470 (41%), Gaps = 75/470 (15%)
Query: 750 EYRKYLELNNNDIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYIN 809
E ++ L N+++A + Y+T + E E L ++ L + + +
Sbjct: 1359 ELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR--LQEAEEHVEAVNAKCAS 1416
Query: 810 TDNVKQSLSKK---------RKALATSVLDILAKNLHK--------------EVDSICEE 846
+ KQ L + R A + LD +N K E+++ +E
Sbjct: 1417 LEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKE 1476
Query: 847 FRSISRKIYEKPN----SIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLYNL 902
RS+S ++++ N S+++L LR K + + + L E+I + +++ +
Sbjct: 1477 SRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQV 1536
Query: 903 SSDDFN-----DKWIAS--NWPSKILG-QIELVQQQHVEDEEKFRKIQIMDQ--NNFQEK 952
+ ++ AS + KIL Q+EL Q + D + K + +DQ N
Sbjct: 1537 EQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRV 1596
Query: 953 LEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLK-DCQQLAMLYNNRERIFSLPITNYD 1011
+E +Q ++ EI N+ RVKK+++ D ++ + N+ R+ + + NY
Sbjct: 1597 VETMQS-----TLDAEIRSR----NDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYR 1647
Query: 1012 KLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAID--AEQLEKNVVEAFKTMHKCVK 1069
++KE Q +LD D LR E + + L+ ++ A L+ + E + T+ + +
Sbjct: 1648 NTQGILKETQLHLD------DALRGQED-LKEQLAIVERRANLLQAEIEELWATLEQTER 1700
Query: 1070 QFKDMPACQEVALDIRARIE----EFKPYIPLIQGLRNPGMRIRH--WETLSNQININVR 1123
K ++ LD R++ + I + L N +++ E + N +
Sbjct: 1701 SRK---IAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEK 1757
Query: 1124 PKANLTFARCL------EMNLQDHIESISKVAEVAGKEYAIEQALDKMEK 1167
K +T A + E + H+E + K E K+ ++ LD+ E+
Sbjct: 1758 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKD--LQHRLDEAEQ 1805
>gi|112734867 retinitis pigmentosa GTPase regulator interacting
protein 1 [Homo sapiens]
Length = 1286
Score = 41.6 bits (96), Expect = 0.017
Identities = 54/266 (20%), Positives = 113/266 (42%), Gaps = 9/266 (3%)
Query: 759 NNDIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLS 818
N + S L+ Q L ++E V +R K++L S ++ ++L
Sbjct: 250 NFEQRSSLECAQKAAELRASIKEKVEL-IRLKKLLHERNASLVMTKAQLTEVQEAYETLL 308
Query: 819 KKRKALATSVLDILAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMKGIPERL 878
+K + + ++ + L K +V+ + E + S+K + +E+++ L+ +K ER+
Sbjct: 309 QKNQGILSAAHEALLK----QVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERV 364
Query: 879 VGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKF 938
LE+ + D+Y + E + + S W ++ Q+ +Q Q + E
Sbjct: 365 EDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDK 424
Query: 939 RKIQIMDQNNFQEKLEGLQLVVAGF--SIHVEISRAHEIANEVRRVKKQLKDCQQLAMLY 996
RK+ +++ + + + E L+L V E+ A + +Q + A+L
Sbjct: 425 RKV-LLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQ 483
Query: 997 NNRERIFSLPITNYD-KLSRMVKEFQ 1021
N + S P + KLS+++ E Q
Sbjct: 484 ENTQIEPSEPKNQEEKKLSQVLNELQ 509
>gi|210147558 hypothetical protein LOC202051 [Homo sapiens]
Length = 205
Score = 41.6 bits (96), Expect = 0.017
Identities = 31/151 (20%), Positives = 66/151 (43%), Gaps = 7/151 (4%)
Query: 3041 RAMHKYHFVAKAVEPKRQALLEAQDD-----LGVTQRILDEAKQRLREVEDGIATMQAKY 3095
+A+ K KA K + LL +++ LG + + + ++ E ++++++K
Sbjct: 54 QAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKV 113
Query: 3096 RECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVLVAA 3155
+ +KK++L KC + E + + ++NG +E Q+ + + + N D +
Sbjct: 114 LQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQK 173
Query: 3156 GFVAYLGPFTGQYRTVLYDSWVKQLRSHNVP 3186
+Y+ Q S +Q RSH P
Sbjct: 174 QQESYMAQVLDQKHKKA--SGTRQARSHQHP 202
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 41.6 bits (96), Expect = 0.017
Identities = 136/734 (18%), Positives = 286/734 (38%), Gaps = 112/734 (15%)
Query: 2758 LNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLA-ELTRHNYVTPKSYLELLH---I 2813
L + EL+ +E+Q LI S ++ + YL+ +L+ K E++ +
Sbjct: 1384 LEHLRELQPKLDELQKLI--------SKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDL 1435
Query: 2814 FSILIGQKKLELKTAKNRMKS---GLDKLLRTSEDVAK-------MQEDLESMHPLLEEA 2863
L Q +++ K R+K L ++ + E++ + +Q L++ +EA
Sbjct: 1436 IKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEA 1495
Query: 2864 AKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDA---QKDLDEALPAL 2920
K+ E++ + E S+ E + + + K+ + Q++ D+ + +
Sbjct: 1496 LKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEM 1555
Query: 2921 DAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWE 2980
D +L ++L+ + + A++ + +++ + + +K K+ + ++ E
Sbjct: 1556 DRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEI---ESLKSSKI------AESTEWQE 1606
Query: 2981 PGKGLLQDPGHFLESLFKFDKD-----NIGDVVIKAIQPYIDNEEFQPATIAKVSKACTS 3035
K L ++ L+S + ++ + V + Q A + K
Sbjct: 1607 KHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQE 1666
Query: 3036 ICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLR-EVEDGIATMQAK 3094
Q + M + + K + K+Q +LE L+E RLR EV T +
Sbjct: 1667 AEQEMEEMKEK--MRKFAKSKQQKILE-----------LEEENDRLRAEVHPAGDTAKEC 1713
Query: 3095 YRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVLVA 3154
++ ++ + E+ + K L EK E V++L++ I G+V
Sbjct: 1714 METLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQ---IEGNVSKQ 1770
Query: 3155 AGFVAYLGPFTGQYRTVLYDSW--VKQLRSHNVP-HTSEPTLIGTLGNPVKIRSWQIAGL 3211
A A T +D+ V + + ++P T E + P S A
Sbjct: 1771 ANLEA----------TEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKS 1820
Query: 3212 PNDTLSVE---NGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGLDVFKLSDRDFLRSME 3268
N +S + + IN + Q+ ID E+ GL+ K +++F +++E
Sbjct: 1821 ANPAVSKDFSSHDEINNYLQQ----IDQLK---------ERIAGLEEEKQKNKEFSQTLE 1867
Query: 3269 NAIRFGKPCLLENVGE---ELDPALEPV----LLKQTYKQQGNTVLKLGDTVIPYHEDFR 3321
N K LL + EL E V LL Q +++ + V KL +T +D
Sbjct: 1868 NE----KNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLE 1923
Query: 3322 MYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERP---DLEEAKNQLII 3378
+ +L E++ + ++ + ++++LL + + +LEE K QL+
Sbjct: 1924 ERLMNQLA------ELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVK 1977
Query: 3379 SNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEI-------QAKVRI 3431
K+ E++ + + GN EL ++L+ + + ++ Q K+
Sbjct: 1978 EKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISA 2037
Query: 3432 AEQTEKDIDLTRME 3445
E+T K ++ + E
Sbjct: 2038 LERTVKALEFVQTE 2051
Score = 40.0 bits (92), Expect = 0.050
Identities = 70/351 (19%), Positives = 151/351 (43%), Gaps = 53/351 (15%)
Query: 2820 QKKLEL-KTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDT 2878
QK E +T +N + L ++ ++ +QE++ M+ LL + ++ + + ++K
Sbjct: 1857 QKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMN-LLNQQIQEELSRVTKLK--- 1912
Query: 2879 AIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALP--ALDAALASLRNLNKNDVT 2936
AEE ++ + EE N+ A+ +I + Q D + L++ + +L+
Sbjct: 1913 ETAEEEKDDL--EERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEE 1970
Query: 2937 EVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTK-----VDDYWEPGKGLLQDPGH 2991
E + + + V+ I + K +K PG K K + + + K L +D
Sbjct: 1971 EKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIR 2030
Query: 2992 FLESLFKFDKDNIGDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAK 3051
+ E + ++ +KA++ ++ E + I K + +A+
Sbjct: 2031 YQEKISALER------TVKALE-FVQTESQKDLEITKEN------------------LAQ 2065
Query: 3052 AVEPKRQALLEA-------QDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEE 3104
AVE +++A E D R+L + + +E++ +++++ ++ K E+
Sbjct: 2066 AVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQ---KDED 2122
Query: 3105 LELKCEQCEQRLGRAGK----LINGLSDEKVRWQETVENLQYMLNNISGDV 3151
LE + EQ E++ + K ++ L EKV +ET+ +Q LN +V
Sbjct: 2123 LERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEV 2173
Score = 38.5 bits (88), Expect = 0.14
Identities = 71/401 (17%), Positives = 159/401 (39%), Gaps = 66/401 (16%)
Query: 2767 SQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELK 2826
+Q E+Q +VC + Q +K+ + L E TRH Y + ++ EL
Sbjct: 2268 AQTEVQLQQKVCDTL-QGENKELLSQLEE-TRHLYHSSQN-----------------ELA 2308
Query: 2827 TAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKD---TMLTMEQIKVDTAIAEE 2883
++ +KS D+L S + K +E ++ ++ + D + + EQ++ D + E
Sbjct: 2309 KLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRE 2368
Query: 2884 TRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPAL----DAALASLRNLNKNDVTEVR 2939
+ + E N K +K ++ ++ + A+ L D + L NL + E
Sbjct: 2369 LTSRLHEE---INMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENI 2425
Query: 2940 AMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKF 2999
++ K V + +M+ +K K + ++D + + L D + +
Sbjct: 2426 VLEEE--NKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQL 2483
Query: 3000 DKDNIGDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQA 3059
++ ++ ++ K I + + + + +R + + + K A
Sbjct: 2484 EERHLSIILEK------------DQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDA 2531
Query: 3060 -LLEAQDDLGVTQRILDEAKQRL--------REVEDGIATMQAKYRECITKKEELELKCE 3110
L++ ++DL I D +++L +E+E+ A ++ K +E E+L
Sbjct: 2532 ELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLR---- 2587
Query: 3111 QCEQRLGRAGKLINGLSDEKVRWQETVENLQYMLNNISGDV 3151
+ N L +EK + +E+L+ ++ ++ V
Sbjct: 2588 ----------RSFNALQEEKQDLSKEIESLKVSISQLTRQV 2618
Score = 34.3 bits (77), Expect = 2.7
Identities = 72/363 (19%), Positives = 150/363 (41%), Gaps = 34/363 (9%)
Query: 643 GDDLINSPYRPRKNPLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATHAVPQLEK 702
G D++ + + + L ++ L + + + Q + D +L + Q+E
Sbjct: 544 GQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEG 603
Query: 703 LVMEDIFISGDPLLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNNDI 762
+ I + LE G PL+ +++ AV K + + R E++ ND
Sbjct: 604 EGIAPIKMK--VFLEDTGQDFPLMPNEESSLP-AVEKEQASTE---HQSRTSEEISLNDA 657
Query: 763 ASFLKTYQTQGLLA-QEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKKR 821
LK+ + G + V ++ H E E L S + + F+ + +++L +K
Sbjct: 658 GVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELEL--NFHKAQEIYEKNLDEKA 715
Query: 822 KALATSVLDILAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLVGL 881
K ++ L+ L + K D+ F ++S + + + ++EL+ + E + + + L
Sbjct: 716 KEISN--LNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNL 773
Query: 882 EERIVKVMDDYQ-------VMDEFLYNLSSDDFNDKWIASNWPSKI---LGQIELVQQQH 931
E + DY+ ++ E +++LS + A + KI +++ VQ Q
Sbjct: 774 AEAERQRRLDYESQTAHDNLLTEQIHSLSIE-------AKSKDVKIEVLQNELDDVQLQF 826
Query: 932 VEDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQ 991
E R +Q QN E LEG + V H+ S+ E++ + + + ++ Q
Sbjct: 827 SEQSTLIRSLQSQLQNKESEVLEGAERV-----RHIS-SKVEELSQALSQKELEITKMDQ 880
Query: 992 LAM 994
L +
Sbjct: 881 LLL 883
Score = 33.9 bits (76), Expect = 3.6
Identities = 78/371 (21%), Positives = 149/371 (40%), Gaps = 55/371 (14%)
Query: 815 QSLSKKRKALATSVLDILAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMKGI 874
+S ++ L V D L + +KE+ S EE +R +Y +S ELA+L +K +
Sbjct: 2265 ESKAQTEVQLQQKVCDTL-QGENKELLSQLEE----TRHLYH--SSQNELAKLESELKSL 2317
Query: 875 PERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHVED 934
++L L + K + ++ + +D N K+ + + EL + H E
Sbjct: 2318 KDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEI 2377
Query: 935 EEKFRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQLAM 994
K +KI + K E +Q+ +A E+ + H+ K++K+ + L
Sbjct: 2378 NMKEQKIISL----LSGKEEAIQVAIA------ELRQQHD---------KEIKELENL-- 2416
Query: 995 LYNNRERIFSLPITN---YDKLSRMVKEFQPY----LDLWTTASDWLRWSESWMNDPLSA 1047
L E L N DK +++++ + + +++ S ND
Sbjct: 2417 LSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRI 2476
Query: 1048 I-DAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGM 1106
+ D +QLE+ H + KD QE A + EE + + L +
Sbjct: 2477 VGDYQQLEER--------HLSIILEKDQ-LIQEAAAENNKLKEEIRGLRSHMDDLNSENA 2527
Query: 1107 R-----IRHWETLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQA 1161
+ I++ E L+ I I + L LE+ LQ + E +K A++ K E+A
Sbjct: 2528 KLDAELIQYREDLNQVITIKDSQQKQL-----LEVQLQQNKELENKYAKLEEKLKESEEA 2582
Query: 1162 LDKMEKEWSTI 1172
+ + + ++ +
Sbjct: 2583 NEDLRRSFNAL 2593
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 40.8 bits (94), Expect = 0.029
Identities = 80/375 (21%), Positives = 145/375 (38%), Gaps = 64/375 (17%)
Query: 2818 IGQKKLELKTAKNRMKS-------GLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLT 2870
+ +K+ EL+ A R++ L K+ ++++QEDLES +A K
Sbjct: 1078 LAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDL 1137
Query: 2871 MEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNL 2930
E+++ E+T +S ++ E K + + +K L+E +A + +R
Sbjct: 1138 GEELEALKTELEDTLDSTAAQQ----ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQK 1193
Query: 2931 NKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPG 2990
+ V E+ VK +E K K+ + G ++ K LLQ G
Sbjct: 1194 HSQAVEELAEQLEQTKRVKANLE--------KAKQTLENERGELANEV----KVLLQGKG 1241
Query: 2991 -----------HFLESLFKFD-----KDNIGDVVIKAIQPYIDN-------EEFQPATIA 3027
E KF+ + + D V K +Q +DN + + + +
Sbjct: 1242 DSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTK-LQVELDNVTGLLSQSDSKSSKLT 1300
Query: 3028 KVSKACTSICQWVRAMHKYHFVAKAVEPKRQ------ALLEAQDDLGVTQRILDEAKQRL 3081
K A S Q + + + E RQ L + +D+ + L+E ++
Sbjct: 1301 KDFSALESQLQDTQELLQ--------EENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAK 1352
Query: 3082 REVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLS---DEKVRWQETVE 3138
+E IAT+ A+ + K E+ E E+ + K + GLS +EKV + +E
Sbjct: 1353 HNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLE 1412
Query: 3139 NLQYMLNNISGDVLV 3153
+ L D+LV
Sbjct: 1413 KTKTRLQQELDDLLV 1427
Score = 39.3 bits (90), Expect = 0.085
Identities = 52/297 (17%), Positives = 130/297 (43%), Gaps = 33/297 (11%)
Query: 749 KEYRKYLELNNNDIASFLKTYQTQGLLAQEVREVV--LTHLRE--------KEILDSSLP 798
K+ + + +A++ K +T+ L QE+ +++ L H R+ ++ D L
Sbjct: 1392 KDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLA 1451
Query: 799 SSIIIGPFYINTDNVKQSLSKKRKALATSVLDILAKNLHK--EVDSICEEFRSISRKIYE 856
I Y + ++ +++++ A S+ L + + + E++ + ++FR+ +
Sbjct: 1452 EEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMS 1511
Query: 857 KPNSI-EELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLYNLSSD---------- 905
+ + + + EL + + + +++ ++ ++ ++ D+ Q ++ L +
Sbjct: 1512 SKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFER 1571
Query: 906 DFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSI 965
D + S K L + + +EDE K R + + + + L+ L+
Sbjct: 1572 DLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEA------- 1624
Query: 966 HVEISRAH--EIANEVRRVKKQLKDC-QQLAMLYNNRERIFSLPITNYDKLSRMVKE 1019
H++ + + E ++R+++ Q+KDC ++L +RE I + N KL M E
Sbjct: 1625 HIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAE 1681
Score = 35.4 bits (80), Expect = 1.2
Identities = 56/312 (17%), Positives = 126/312 (40%), Gaps = 42/312 (13%)
Query: 2837 DKLLRTSEDVAKMQE-DLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKA 2895
++++ E++ K++E L + + L E + L E++++ + ET + EE++A
Sbjct: 845 EEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRA 904
Query: 2896 NEKAKK--AQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIE 2953
AKK + I D + ++E A + + +N + E+ + ++
Sbjct: 905 RLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQN-IQELEEQLEEEESARQKLQ 963
Query: 2954 AVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQ 3013
+ K KK+ E+ +L+D L K +D I +
Sbjct: 964 LEKVTTEAKLKKLEEEQI-------------ILEDQNCKLAKEKKLLEDRIAEFTTN--- 1007
Query: 3014 PYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRI 3073
+ EE + ++AK+ +K+ + +E + + + + +L T+R
Sbjct: 1008 --LTEEEEKSKSLAKLK-------------NKHEAMITDLEERLRREEKQRQELEKTRRK 1052
Query: 3074 LDEAKQRLREVEDGIATMQAKYRE----CITKKEELELKCEQCEQRLGRAGKLINGLSDE 3129
L+ ++ D IA +QA+ E K+EEL+ + E+ + + + +
Sbjct: 1053 LEGDS---TDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIREL 1109
Query: 3130 KVRWQETVENLQ 3141
+ + E E+L+
Sbjct: 1110 ESQISELQEDLE 1121
Score = 34.7 bits (78), Expect = 2.1
Identities = 20/93 (21%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Query: 2820 QKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTA 2879
++K EL+ + ++ ++ L+ + +DV K +LE LE+ ++ +E+++ +
Sbjct: 1490 EQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQ 1549
Query: 2880 IAEETRNSVQTEEIKANEKAKKAQAIADDAQKD 2912
E+ + ++ N +A KAQ D +D
Sbjct: 1550 ATEDAK-----LRLEVNLQAMKAQFERDLQGRD 1577
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 39.7 bits (91), Expect = 0.065
Identities = 124/664 (18%), Positives = 267/664 (40%), Gaps = 112/664 (16%)
Query: 749 KEYRKYLELNNNDIASFLKTYQTQGLLAQEVREVVLTHLRE-KEILDSSLPSSIIIGPFY 807
KE +K E + + +++ + GL +E ++ HL+E +E +D S
Sbjct: 1206 KELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQI 1265
Query: 808 INTDNVKQSLSKKRKALATSVLDILAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAEL 867
INT ++++S +K ++ + LH+E +E +++ E ++ EL L
Sbjct: 1266 INTQDLEKSHTKLQEEIPV---------LHEE-----QELLPNVKEVSETQETMNELELL 1311
Query: 868 REWMKGIPER-LVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIEL 926
E L +E +++ + +Q E + +L+ + N K I E
Sbjct: 1312 TEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIK-----------EA 1360
Query: 927 VQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQL 986
++ +H + +E R+ Q + ++ + L + + + +I +E+ + K
Sbjct: 1361 LEVKHDQLKEHIRETLAKIQESQSKQEQSLNM-------KEKDNETTKIVSEMEQFKP-- 1411
Query: 987 KDCQQLAMLYNNRERIFSLPIT-----NYDKLSRMVKE---FQPYLDLWTTASDWLRWSE 1038
KD L R I L ++ ++D++ + KE Q ++ + SD L+
Sbjct: 1412 KDSALL------RIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLK--- 1462
Query: 1039 SWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLI 1098
+ + I A+ LE E K H C+K+ +E ++R + E + I I
Sbjct: 1463 ----ENIKEIVAKHLETE--EELKVAHCCLKEQ------EETINELRVNLSEKETEISTI 1510
Query: 1099 QGLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAG----- 1153
Q + E +++++ ++ E Q +I+ IS+V E
Sbjct: 1511 Q---------KQLEAINDKLQNKIQ--------EIYEKEEQFNIKQISEVQEKVNELKQF 1553
Query: 1154 KEY--AIEQALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSP 1211
KE+ A + AL +E + + + + ++K +E ++ + +
Sbjct: 1554 KEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQE---------ALQI 1604
Query: 1212 YKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQLPVESKRYQTME 1271
+ ++ K+K +QE ++L E + E + +Q + + +E
Sbjct: 1605 ERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIE 1664
Query: 1272 ----RIWKKIMKNAYENREVINVCSDLRMLDSLR--DCNKILDLVQKGLSEYLETKRSAF 1325
R+ + + +N E R V DLR ++ + +++ + +++ ++ LE +
Sbjct: 1665 TENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELK 1724
Query: 1326 PRFYFLSD-----DELLEILSQ-TKDPTAVQPHLRKCFENIAR--LLFQEDLEITHMYSA 1377
L + D+L I+S+ T + + +Q L + + L QE+L I HM+
Sbjct: 1725 IVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLK 1784
Query: 1378 EGEE 1381
E +E
Sbjct: 1785 EQQE 1788
Score = 37.0 bits (84), Expect = 0.42
Identities = 110/607 (18%), Positives = 236/607 (38%), Gaps = 85/607 (14%)
Query: 834 KNLHKEVDSICEEFRSISRKIY----EKPNSIEELAELREWMKGIPERLVGLEERIVKVM 889
K+L EV+ + +E + S +++ EK E+ ++G+ E + ++ +
Sbjct: 750 KSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQ 809
Query: 890 DDYQVMDEFLYNLSS--DDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQN 947
+Y+ D+ N + DF K+ +L + E + Q+ V ++ +K
Sbjct: 810 SNYKSTDQEFQNFKTLHMDFEQKY------KMVLEENERMNQEIVNLSKEAQK------- 856
Query: 948 NFQEKLEGLQLVVAGFSIHVEIS-RAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLP 1006
F L L+ E+S + E+ + R V+++L + +QL NR+
Sbjct: 857 -FDSSLGALK---------TELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTV 906
Query: 1007 ITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEA----FK 1062
++ +++ + T D L+ + + I+ +QL+ ++ +
Sbjct: 907 EREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQ-----IERDQLKSDIHDTVNMNID 961
Query: 1063 TMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWET----LSNQI 1118
T + + + QE ++++I E + RN M ET +
Sbjct: 962 TQEQLRNALESLKQHQETINTLKSKISE--------EVSRNLHMEENTGETKDEFQQKMV 1013
Query: 1119 NINVRPKANLTFARCLEMNLQDH--IESISKVAEVAGKEYAIEQALDKMEKEWSTILFNV 1176
I+ + + L +++D+ IE K+ + ++ ++Q L+ + E + ++
Sbjct: 1014 GIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDL 1073
Query: 1177 LPYKATDTYILKSPDEASQLLDDHIVMTQNM----SFSPYKKPFE-----QRINSWENKL 1227
K +++ +E +LL D + Q + KK E R+ E KL
Sbjct: 1074 ---KENIEMTIENQEEL-RLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKL 1129
Query: 1228 K----LTQEVLEEWLNCQRSWLYLE-PIFSSEDINQQLPVESKRYQTMERIWKKIMKNAY 1282
K QE ++ LN Q ++ I E++ +L + + ME ++ +
Sbjct: 1130 KEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLN 1189
Query: 1283 ENREVINVCSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEI--L 1340
EN E + + R + L++ K + + L Y+ + L E L+I +
Sbjct: 1190 ENYEEVKSITKERKV--LKELQKSFETERDHLRGYIREIEAT-----GLQTKEELKIAHI 1242
Query: 1341 SQTKDPTAVQPHLRKCFENIARLLFQEDLEITHMYSAE-----GEEVQLCFSIYPSSNVE 1395
+ + R E A+++ +DLE +H E EE +L ++ S +
Sbjct: 1243 HLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQ 1302
Query: 1396 DWLREVE 1402
+ + E+E
Sbjct: 1303 ETMNELE 1309
Score = 34.3 bits (77), Expect = 2.7
Identities = 54/321 (16%), Positives = 132/321 (41%), Gaps = 35/321 (10%)
Query: 761 DIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKK 820
+I + ++TQ L + + ++R +IL +L + + +V+++L +
Sbjct: 1645 EIEHLKEQFETQKL---NLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVE 1701
Query: 821 RKALATSVLDILAKNLHKEVDSICEEFRSISRKIYEKPNSIEELA--------ELREWMK 872
R L ++ + + ++L K+ EE + + + E +I++L E+ K
Sbjct: 1702 RDQLKENLRETITRDLEKQ-----EELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQK 1756
Query: 873 GIPERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHV 932
+ L+ + +K+ ++ ++ L + I S K+ + ++ +
Sbjct: 1757 DLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNA 1816
Query: 933 EDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQL 992
+ +EK ++++ + QL+ ++ +++ + +E+ ++KKQ+KD Q L
Sbjct: 1817 KLQEKIQELKANEH----------QLI----TLKKDVNETQKKVSEMEQLKKQIKD-QSL 1861
Query: 993 AMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQ 1052
+ E + +L ++ L M K D + L+ + + L A
Sbjct: 1862 TLSKLEIENL-NLAQKLHENLEEM-KSVMKERDNLRRVEETLKLERDQLKESLQETKARD 1919
Query: 1053 LEKNVVEAFKTMHKCVKQFKD 1073
LE + + KT K+ K+
Sbjct: 1920 LE--IQQELKTARMLSKEHKE 1938
Score = 33.5 bits (75), Expect = 4.6
Identities = 59/265 (22%), Positives = 103/265 (38%), Gaps = 44/265 (16%)
Query: 2666 IPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRA 2725
+PN+ E + ++ + + EQ L R+R N E F+
Sbjct: 1292 LPNVKEVSETQETMNELE-LLTEQSTTKDSTTLARIEMERLRLN-----------EKFQE 1339
Query: 2726 RLRQFPSLV----NCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQVCVYI 2781
+ SL N TI E + LK L +I E +S QE+
Sbjct: 1340 SQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQ----------- 1388
Query: 2782 HQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLR 2841
++ +K E ++ PK LL I ++G K L+ + + MKS + +
Sbjct: 1389 SLNMKEKDNETTKIVSEMEQFKPKDSA-LLRIEIEMLGLSK-RLQESHDEMKS----VAK 1442
Query: 2842 TSEDVAKMQEDLESMHPLLEEAAKDTML----TMEQIKVDTAIAEETRNSVQTEEIKANE 2897
+D+ ++QE L+S L+E K+ + T E++KV +E ++ + +E
Sbjct: 1443 EKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSE 1502
Query: 2898 K-------AKKAQAIADDAQKDLDE 2915
K K+ +AI D Q + E
Sbjct: 1503 KETEISTIQKQLEAINDKLQNKIQE 1527
Score = 33.1 bits (74), Expect = 6.1
Identities = 43/170 (25%), Positives = 80/170 (47%), Gaps = 15/170 (8%)
Query: 2760 EIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIG 2819
+I EL++++ ++ L + + VS+ +E L + + +T L L I ++ +
Sbjct: 1821 KIQELKANEHQLITLKKDVNETQKKVSE--MEQLKKQIKDQSLT----LSKLEIENLNLA 1874
Query: 2820 QKKLE-LKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDT 2878
QK E L+ K+ MK + LR E+ K++ D + L E A+D + E +K
Sbjct: 1875 QKLHENLEEMKSVMKERDN--LRRVEETLKLERD-QLKESLQETKARDLEIQQE-LKTAR 1930
Query: 2879 AIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLR 2928
+++E + +V K EK + D QKDLD++ L + L+
Sbjct: 1931 MLSKEHKETVD----KLREKISEKTIQISDIQKDLDKSKDELQKKIQELQ 1976
>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
[Homo sapiens]
Length = 8749
Score = 38.9 bits (89), Expect = 0.11
Identities = 122/609 (20%), Positives = 242/609 (39%), Gaps = 92/609 (15%)
Query: 912 IASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEK---LEGLQLVVAGFSIHVE 968
+ S W + + +L Q D++ +Q Q +EK L+ LQ +++ H
Sbjct: 2738 VISQWNDYVERKNQLEQWMESVDQKIEHPLQ--PQPGLKEKFVLLDHLQSILSEAEDHTR 2795
Query: 969 ISRAHEIANEVRRVKKQLKD-------CQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQ 1021
H + + R + ++ +D ++L +N+ I ++ K+ +VK+
Sbjct: 2796 A--LHRLIAKSRELYEKTEDESFKDTAQEELKTQFND---IMTVAKEKMRKVEEIVKDHL 2850
Query: 1022 PYLDLWTTASDWL--------RWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKD 1073
YLD +DWL RWS+ M+ SA K + + K+
Sbjct: 2851 MYLDAVHEFTDWLHSAKEELHRWSD--MSGDSSA----------------TQKKLSKIKE 2892
Query: 1074 MPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARC 1133
+ +E+ +R+E P + Q G + H E + + + + C
Sbjct: 2893 LIDSREIGASRLSRVESLAPEVK--QNTTASGCELMHTEMQALRADWKQWEDSVFQTQSC 2950
Query: 1134 LEMNLQDHIESISKVAEVAGKEYAIEQALDKME---KEWSTILFNVLPYKATDTYILKSP 1190
LE NL + ++S+ E +G+ +EQAL++ K W+ L +L K TD I++
Sbjct: 2951 LE-NLVSQM-ALSE-QEFSGQVAQLEQALEQFSALLKTWAQQL-TLLEGKNTDEEIVECW 3006
Query: 1191 DEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPI 1250
+ ++LD +P + + S N+L L + +
Sbjct: 3007 HKGQEILD----------ALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSGLI----- 3051
Query: 1251 FSSEDINQQLPVESKRYQTMERIWKKIMKNAYENRE--VINV-CSDLRMLDSLRDCNKIL 1307
++ N SK Q E+I ++ + A+ + + ++N + + D ++ +++
Sbjct: 3052 ---KEYNCLCLQASKGCQNKEQILQQRFRKAFRDFQQWLVNAKITTAKCFDIPQNISEVS 3108
Query: 1308 DLVQKGLSEYL-ETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHL---RKCFENIARL 1363
+QK + E+L E++ LS ELL L + +Q + ++ ++N
Sbjct: 3109 TSLQK-IQEFLSESENGQHKLNMMLSKGELLSTLLTKEKAKGIQAKVTAAKEDWKNFHSN 3167
Query: 1364 LFQEDLEITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIEKAIRAYPTM 1423
L Q++ + E ++Q+ + ++DWL + E+ + S + + + +
Sbjct: 3168 LHQKESAL------ENLKIQMKDFEVSAEPIQDWLSKTEKMVHESSNRLYDLPAKR-REQ 3220
Query: 1424 PRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLRSQLFPQLCQQLSD----LVALVRG 1479
+ Q VL ++ Q E A+ L G S+ F QLS L L +
Sbjct: 3221 QKLQSVLE---EIHCYEPQLNRLKEKAQQLWEGQAASKSFRHRVSQLSSQYLALSNLTKE 3277
Query: 1480 KLSRMQRAV 1488
K+SR+ R V
Sbjct: 3278 KVSRLDRIV 3286
Score = 38.1 bits (87), Expect = 0.19
Identities = 102/547 (18%), Positives = 216/547 (39%), Gaps = 76/547 (13%)
Query: 760 NDIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTD--NVKQSL 817
ND+ L T + E+ E + K+ +D+S S+I ++ ++Q+L
Sbjct: 7216 NDLLKGLGTVKDSLFFLHELGEQL------KQQVDASAASAIQSDQLSLSQHLCALEQAL 7269
Query: 818 SKKRKALATSVLDI--LAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMKGIP 875
K++ +L VLD AK+L I E + + P+ +L+ ++E M
Sbjct: 7270 CKQQTSLQAGVLDYETFAKSLEALEAWIVEAEEILQG---QDPSHSSDLSTIQERM---- 7322
Query: 876 ERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIAS---NWPSKILGQIELVQQQHV 932
E L G + + D ++E Y L +D K + + +W L+ Q
Sbjct: 7323 EELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHW--------SLISSQTT 7374
Query: 933 EDEEKFRKIQ--IMDQNNFQEKLEGLQ--LVVAGFSIHVEISRAHEIANEVRRVKKQLKD 988
E +F K+Q ++ F EK E LV + VEIS ++ E +R + +
Sbjct: 7375 E---RFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAHELFQ- 7430
Query: 989 CQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAI 1048
A +++ ++ + S+ I L + + + +L T S W I
Sbjct: 7431 ----AEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLL-----SNQWQG----VI 7477
Query: 1049 DAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRI 1108
Q + ++++ Q + +E+A +R + E Y+P+ GL + + +
Sbjct: 7478 RRAQQRRGIIDS---------QIRQWQRYREMAEKLRKWLVEVS-YLPM-SGLGSVPIPL 7526
Query: 1109 RHWETLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKE 1168
+ TL +++ + + L + + ++ +G E A++ L +++++
Sbjct: 7527 QQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQL----LLSADSGAEAALQAELAEIQEK 7582
Query: 1169 WSTILFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLK 1228
W + + K ++LK ++ + + D + + +KK Q + +L
Sbjct: 7583 WKSASMRLEEQKKKLAFLLKDWEKCEKGIADSLEKLRT-----FKKKLSQSLPDHHEELH 7637
Query: 1229 LTQEVLEEWLNCQRSWL-------YLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNA 1281
Q +E N SW L+ S+ + + ++R + ++R W+++
Sbjct: 7638 AEQMRCKELENAVGSWTDDLTQLSLLKDTLSAYISADDISILNERVELLQRQWEELCHQL 7697
Query: 1282 YENREVI 1288
R+ I
Sbjct: 7698 SLRRQQI 7704
>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
[Homo sapiens]
Length = 8797
Score = 38.9 bits (89), Expect = 0.11
Identities = 122/609 (20%), Positives = 242/609 (39%), Gaps = 92/609 (15%)
Query: 912 IASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEK---LEGLQLVVAGFSIHVE 968
+ S W + + +L Q D++ +Q Q +EK L+ LQ +++ H
Sbjct: 2731 VISQWNDYVERKNQLEQWMESVDQKIEHPLQ--PQPGLKEKFVLLDHLQSILSEAEDHTR 2788
Query: 969 ISRAHEIANEVRRVKKQLKD-------CQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQ 1021
H + + R + ++ +D ++L +N+ I ++ K+ +VK+
Sbjct: 2789 A--LHRLIAKSRELYEKTEDESFKDTAQEELKTQFND---IMTVAKEKMRKVEEIVKDHL 2843
Query: 1022 PYLDLWTTASDWL--------RWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKD 1073
YLD +DWL RWS+ M+ SA K + + K+
Sbjct: 2844 MYLDAVHEFTDWLHSAKEELHRWSD--MSGDSSA----------------TQKKLSKIKE 2885
Query: 1074 MPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARC 1133
+ +E+ +R+E P + Q G + H E + + + + C
Sbjct: 2886 LIDSREIGASRLSRVESLAPEVK--QNTTASGCELMHTEMQALRADWKQWEDSVFQTQSC 2943
Query: 1134 LEMNLQDHIESISKVAEVAGKEYAIEQALDKME---KEWSTILFNVLPYKATDTYILKSP 1190
LE NL + ++S+ E +G+ +EQAL++ K W+ L +L K TD I++
Sbjct: 2944 LE-NLVSQM-ALSE-QEFSGQVAQLEQALEQFSALLKTWAQQL-TLLEGKNTDEEIVECW 2999
Query: 1191 DEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPI 1250
+ ++LD +P + + S N+L L + +
Sbjct: 3000 HKGQEILD----------ALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSGLI----- 3044
Query: 1251 FSSEDINQQLPVESKRYQTMERIWKKIMKNAYENRE--VINV-CSDLRMLDSLRDCNKIL 1307
++ N SK Q E+I ++ + A+ + + ++N + + D ++ +++
Sbjct: 3045 ---KEYNCLCLQASKGCQNKEQILQQRFRKAFRDFQQWLVNAKITTAKCFDIPQNISEVS 3101
Query: 1308 DLVQKGLSEYL-ETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHL---RKCFENIARL 1363
+QK + E+L E++ LS ELL L + +Q + ++ ++N
Sbjct: 3102 TSLQK-IQEFLSESENGQHKLNMMLSKGELLSTLLTKEKAKGIQAKVTAAKEDWKNFHSN 3160
Query: 1364 LFQEDLEITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIEKAIRAYPTM 1423
L Q++ + E ++Q+ + ++DWL + E+ + S + + + +
Sbjct: 3161 LHQKESAL------ENLKIQMKDFEVSAEPIQDWLSKTEKMVHESSNRLYDLPAKR-REQ 3213
Query: 1424 PRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLRSQLFPQLCQQLSD----LVALVRG 1479
+ Q VL ++ Q E A+ L G S+ F QLS L L +
Sbjct: 3214 QKLQSVLE---EIHCYEPQLNRLKEKAQQLWEGQAASKSFRHRVSQLSSQYLALSNLTKE 3270
Query: 1480 KLSRMQRAV 1488
K+SR+ R V
Sbjct: 3271 KVSRLDRIV 3279
Score = 38.1 bits (87), Expect = 0.19
Identities = 102/547 (18%), Positives = 216/547 (39%), Gaps = 76/547 (13%)
Query: 760 NDIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTD--NVKQSL 817
ND+ L T + E+ E + K+ +D+S S+I ++ ++Q+L
Sbjct: 7287 NDLLKGLGTVKDSLFFLHELGEQL------KQQVDASAASAIQSDQLSLSQHLCALEQAL 7340
Query: 818 SKKRKALATSVLDI--LAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMKGIP 875
K++ +L VLD AK+L I E + + P+ +L+ ++E M
Sbjct: 7341 CKQQTSLQAGVLDYETFAKSLEALEAWIVEAEEILQG---QDPSHSSDLSTIQERM---- 7393
Query: 876 ERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIAS---NWPSKILGQIELVQQQHV 932
E L G + + D ++E Y L +D K + + +W L+ Q
Sbjct: 7394 EELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHW--------SLISSQTT 7445
Query: 933 EDEEKFRKIQ--IMDQNNFQEKLEGLQ--LVVAGFSIHVEISRAHEIANEVRRVKKQLKD 988
E +F K+Q ++ F EK E LV + VEIS ++ E +R + +
Sbjct: 7446 E---RFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAHELFQ- 7501
Query: 989 CQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAI 1048
A +++ ++ + S+ I L + + + +L T S W I
Sbjct: 7502 ----AEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLL-----SNQWQG----VI 7548
Query: 1049 DAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRI 1108
Q + ++++ Q + +E+A +R + E Y+P+ GL + + +
Sbjct: 7549 RRAQQRRGIIDS---------QIRQWQRYREMAEKLRKWLVEVS-YLPM-SGLGSVPIPL 7597
Query: 1109 RHWETLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKE 1168
+ TL +++ + + L + + ++ +G E A++ L +++++
Sbjct: 7598 QQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQL----LLSADSGAEAALQAELAEIQEK 7653
Query: 1169 WSTILFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLK 1228
W + + K ++LK ++ + + D + + +KK Q + +L
Sbjct: 7654 WKSASMRLEEQKKKLAFLLKDWEKCEKGIADSLEKLRT-----FKKKLSQSLPDHHEELH 7708
Query: 1229 LTQEVLEEWLNCQRSWL-------YLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNA 1281
Q +E N SW L+ S+ + + ++R + ++R W+++
Sbjct: 7709 AEQMRCKELENAVGSWTDDLTQLSLLKDTLSAYISADDISILNERVELLQRQWEELCHQL 7768
Query: 1282 YENREVI 1288
R+ I
Sbjct: 7769 SLRRQQI 7775
>gi|195539368 coiled-coil domain containing 149 isoform 2 [Homo
sapiens]
Length = 529
Score = 38.9 bits (89), Expect = 0.11
Identities = 25/112 (22%), Positives = 49/112 (43%), Gaps = 4/112 (3%)
Query: 3039 WVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYREC 3098
W + +Y + +E K++ALL +L Q+ D+ K ++ + +++ KYRE
Sbjct: 15 WQGLVSEYLVCKRKLESKKEALLILSKELDTCQQERDQYKLMANQLRERHQSLKKKYREL 74
Query: 3099 ITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQETVENLQYMLNNISGD 3150
I L + +++ +L+ D E ++ LQ L + GD
Sbjct: 75 IDGDPSLPPE----KRKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGD 122
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 161,004,933
Number of Sequences: 37866
Number of extensions: 7380288
Number of successful extensions: 24272
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 116
Number of HSP's that attempted gapping in prelim test: 22859
Number of HSP's gapped (non-prelim): 1113
length of query: 4265
length of database: 18,247,518
effective HSP length: 123
effective length of query: 4142
effective length of database: 13,590,000
effective search space: 56289780000
effective search space used: 56289780000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.