Guide to the Human Genome
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Search of human proteins with 197927446

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|197927446 sarcosine dehydrogenase precursor [Homo sapiens]
         (918 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|197927446 sarcosine dehydrogenase precursor [Homo sapiens]        1895   0.0  
gi|21361378 sarcosine dehydrogenase precursor [Homo sapiens]         1895   0.0  
gi|24797151 dimethylglycine dehydrogenase precursor [Homo sapiens]    431   e-120
gi|194306651 pyruvate dehydrogenase phosphatase regulatory subun...   429   e-120
gi|44662838 aminomethyltransferase [Homo sapiens]                      70   7e-12
gi|8923708 FAD-dependent oxidoreductase domain containing 1 [Hom...    60   7e-09
gi|13376331 L-2-hydroxyglutarate dehydrogenase precursor [Homo s...    47   8e-05
gi|60499001 pipecolic acid oxidase [Homo sapiens]                      39   0.022
gi|239753433 PREDICTED: hypothetical protein XP_002345652 [Homo ...    32   2.1  
gi|112382257 InaD-like [Homo sapiens]                                  32   2.7  
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    32   2.7  
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    32   2.7  
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    32   2.7  
gi|8923900 cytidine monophospho-N-acetylneuraminic acid syntheta...    31   4.6  
gi|146134388 YLP motif containing 1 [Homo sapiens]                     31   4.6  
gi|53988380 mesothelin isoform 2 preproprotein [Homo sapiens]          31   6.1  

>gi|197927446 sarcosine dehydrogenase precursor [Homo sapiens]
          Length = 918

 Score = 1895 bits (4908), Expect = 0.0
 Identities = 918/918 (100%), Positives = 918/918 (100%)

Query: 1   MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPS 60
           MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPS
Sbjct: 1   MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPS 60

Query: 61  RPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSD 120
           RPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSD
Sbjct: 61  RPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSD 120

Query: 121 VEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESH 180
           VEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESH
Sbjct: 121 VEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESH 180

Query: 181 VLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGI 240
           VLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGI
Sbjct: 181 VLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGI 240

Query: 241 RVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTER 300
           RVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTER
Sbjct: 241 RVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTER 300

Query: 301 IEGIQNMPNVRDHDASVYLRLQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWEVFTQH 360
           IEGIQNMPNVRDHDASVYLRLQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWEVFTQH
Sbjct: 301 IEGIQNMPNVRDHDASVYLRLQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWEVFTQH 360

Query: 361 IEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGC 420
           IEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGC
Sbjct: 361 IEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGC 420

Query: 421 GQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHDEPLAG 480
           GQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHDEPLAG
Sbjct: 421 GQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHDEPLAG 480

Query: 481 RNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGPAPVLEYDYYGAYGSRAHEDYAYRR 540
           RNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGPAPVLEYDYYGAYGSRAHEDYAYRR
Sbjct: 481 RNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGPAPVLEYDYYGAYGSRAHEDYAYRR 540

Query: 541 LLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFSADVSR 600
           LLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFSADVSR
Sbjct: 541 LLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFSADVSR 600

Query: 601 PPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHI 660
           PPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHI
Sbjct: 601 PPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHI 660

Query: 661 TTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLLRAAGH 720
           TTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLLRAAGH
Sbjct: 661 TTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLLRAAGH 720

Query: 721 LVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHW 780
           LVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHW
Sbjct: 721 LVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHW 780

Query: 781 HADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTMEDKVPMFGLE 840
           HADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTMEDKVPMFGLE
Sbjct: 781 HADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTMEDKVPMFGLE 840

Query: 841 AIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMGVTYGAQ 900
           AIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMGVTYGAQ
Sbjct: 841 AIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMGVTYGAQ 900

Query: 901 AHLKSPFDPNNKRVKGIY 918
           AHLKSPFDPNNKRVKGIY
Sbjct: 901 AHLKSPFDPNNKRVKGIY 918


>gi|21361378 sarcosine dehydrogenase precursor [Homo sapiens]
          Length = 918

 Score = 1895 bits (4908), Expect = 0.0
 Identities = 918/918 (100%), Positives = 918/918 (100%)

Query: 1   MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPS 60
           MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPS
Sbjct: 1   MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPS 60

Query: 61  RPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSD 120
           RPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSD
Sbjct: 61  RPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSD 120

Query: 121 VEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESH 180
           VEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESH
Sbjct: 121 VEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESH 180

Query: 181 VLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGI 240
           VLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGI
Sbjct: 181 VLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGI 240

Query: 241 RVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTER 300
           RVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTER
Sbjct: 241 RVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTER 300

Query: 301 IEGIQNMPNVRDHDASVYLRLQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWEVFTQH 360
           IEGIQNMPNVRDHDASVYLRLQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWEVFTQH
Sbjct: 301 IEGIQNMPNVRDHDASVYLRLQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWEVFTQH 360

Query: 361 IEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGC 420
           IEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGC
Sbjct: 361 IEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGC 420

Query: 421 GQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHDEPLAG 480
           GQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHDEPLAG
Sbjct: 421 GQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHDEPLAG 480

Query: 481 RNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGPAPVLEYDYYGAYGSRAHEDYAYRR 540
           RNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGPAPVLEYDYYGAYGSRAHEDYAYRR
Sbjct: 481 RNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGPAPVLEYDYYGAYGSRAHEDYAYRR 540

Query: 541 LLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFSADVSR 600
           LLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFSADVSR
Sbjct: 541 LLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFSADVSR 600

Query: 601 PPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHI 660
           PPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHI
Sbjct: 601 PPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHI 660

Query: 661 TTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLLRAAGH 720
           TTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLLRAAGH
Sbjct: 661 TTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLLRAAGH 720

Query: 721 LVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHW 780
           LVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHW
Sbjct: 721 LVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHW 780

Query: 781 HADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTMEDKVPMFGLE 840
           HADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTMEDKVPMFGLE
Sbjct: 781 HADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTMEDKVPMFGLE 840

Query: 841 AIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMGVTYGAQ 900
           AIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMGVTYGAQ
Sbjct: 841 AIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMGVTYGAQ 900

Query: 901 AHLKSPFDPNNKRVKGIY 918
           AHLKSPFDPNNKRVKGIY
Sbjct: 901 AHLKSPFDPNNKRVKGIY 918


>gi|24797151 dimethylglycine dehydrogenase precursor [Homo sapiens]
          Length = 866

 Score =  431 bits (1108), Expect = e-120
 Identities = 279/845 (33%), Positives = 433/845 (51%), Gaps = 66/845 (7%)

Query: 67  ANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELL 126
           A  V+IGGG +G    YHLAK GM   VLLE+  LT+G+TWH AGL     P  + ++ +
Sbjct: 50  AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPG-INLKKI 108

Query: 127 AHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAE 186
            +    +  +LEEETG   G+ Q G + +A+   R+DE+K  M+    +  E +++ P +
Sbjct: 109 HYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEK 168

Query: 187 TKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTDD 246
            + ++PL+N++ +   LY P DG +DP      LA  A   GA +    PVT ++  +D 
Sbjct: 169 IQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDG 228

Query: 247 FGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTERIEGIQ- 305
                   VET  GS++   +VN AG WA  VG+M G++ PL+ + H YVVT  I  ++ 
Sbjct: 229 -----TWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKA 283

Query: 306 ---NMPNVRDHDASVYLRLQGDALSVGGYEANPIF-----W--EEVSDKFAFGLFDLDWE 355
               +P +RD + S YLR + D L  G YE+         W    V   F   LF+ D +
Sbjct: 284 LKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLD 343

Query: 356 VFTQHIEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMM 415
              +HI+ A+  VPVL+K  I + V GP +++PD  P++G    +R +++  GF   G++
Sbjct: 344 RIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGFGY-GII 402

Query: 416 LGGGCGQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHD 475
             GG G+ L+ WI+HG P  D+   D  R+    T   ++   ++ ESY  N  V +P +
Sbjct: 403 HAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTT--QYTEAKARESYGFNNIVGYPKE 460

Query: 476 EPLAGRNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGPAPVLEYDYYGAYGSRAHED 535
           E  AGR  +R     + L   C      GWE+P WF+  G                  +D
Sbjct: 461 ERFAGRPTQRVSGLYQRLESKCSMGFHAGWEQPHWFYKPG------------------QD 502

Query: 536 YAYRRLLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFS 595
             YR       +F      + +  E        AV D+S FGKF + G D+ +  D LF 
Sbjct: 503 TQYRP------SFRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLF- 555

Query: 596 ADVSRPPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQH 655
           A+V    G T  + ML  +G   ++LTVS  +P               + L  G     H
Sbjct: 556 ANVIPKVGFTNISHMLTPKGRVYAELTVSHQSPGE-------------FLLITGSGSELH 602

Query: 656 NWSHITTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLL 715
           +   I           ++ + +++LG++ + GP +R +LQ++   DLS++ F F   K L
Sbjct: 603 DLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSEDLSDDVFKFLQTKSL 662

Query: 716 RAAGHLVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEK 775
           + +   V A+R+S+ GELGWEL+  +   V +Y A+M AG + G+ N G  A+++L +EK
Sbjct: 663 KVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEK 722

Query: 776 GYRHWHADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTM-EDKV 834
            +R W  ++  D +PLEAGL +  KL  P  F+G++AL+Q +A GL+RRLVC T+  D V
Sbjct: 723 AFRAWGLEMNCDTNPLEAGLEYFVKLNKPADFIGKQALKQIKAKGLKRRLVCLTLATDDV 782

Query: 835 PMFGLEAIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMG 894
              G E+IW NG+VVG+     + ++I K++A+ Y+      PV L  V      +E +G
Sbjct: 783 DPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAYV------PVQLSEV-GQQVEVELLG 835

Query: 895 VTYGA 899
             Y A
Sbjct: 836 KNYPA 840


>gi|194306651 pyruvate dehydrogenase phosphatase regulatory subunit
           [Homo sapiens]
          Length = 879

 Score =  429 bits (1102), Expect = e-120
 Identities = 284/889 (31%), Positives = 451/889 (50%), Gaps = 68/889 (7%)

Query: 37  EKSVPYQRTLKEGQGTSVVAQGPSRPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLL 96
           +++ P  +     + ++  A+  S  LP+ A VV+ GGG  G    YHL+K+G    VLL
Sbjct: 13  QRASPGWQNWSSARNSTSAAEARSMALPTQAQVVICGGGITGTSVAYHLSKMGWKDIVLL 72

Query: 97  ERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIA 156
           E+ RL +G+T   AG+L   R   +E ++  ++ ++   +LE+ETG+ TG+ + G +F+A
Sbjct: 73  EQGRLAAGSTRFCAGILSTARHLTIEQKMADYSNKLYY-QLEQETGIQTGYTRTGSIFLA 131

Query: 157 SNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGT 216
             + RL   KR+ +     G+ S ++SP +   L+ L+NV DL G ++VP D  +  A  
Sbjct: 132 QTQDRLISLKRINAGLNVIGIPSEIISPKKVAELHHLLNVHDLVGAMHVPEDAVVSSADV 191

Query: 217 CTTLARAASARGAQVIENCPVTGIRVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWAS 276
              LA AAS  G Q+ +   V  + V        +V GVET  G I+    VNCAG WA 
Sbjct: 192 ALALASAASQNGVQIYDRTSVLHVMVKKG-----QVTGVETDKGQIECQYFVNCAGQWAY 246

Query: 277 AVG--RMAGVKVPLVAMHHAYVVTERIEGI--QNMPNVRDHDASVYLR-LQGDALSVGGY 331
            +G      V +PL A  H Y++T  +E     + P + D D  +Y+R  QG  LS GG+
Sbjct: 247 ELGLSNEEPVSIPLHACEHFYLLTRPLETPLQSSTPTIVDADGRIYIRNWQGGILS-GGF 305

Query: 332 EANPI-FWEEVSDKFAFGLFDLDWEVFTQHIEGAINRVPVLEKTGIKSTVCGPESFTPDH 390
           E NP   + E  ++        DW+ F   +   + R+P LE   I   V  PE+FTPD 
Sbjct: 306 EKNPKPIFTEGKNQLEIQNLQEDWDHFEPLLSSLLRRMPELETLEIMKLVNCPETFTPDM 365

Query: 391 KPLMGEAPELRGFFLGCGFNSAGMMLGGGCGQELAHWIIHGRPEKDMHGYDIRRFHHSLT 450
           + +MGE+P ++G+F+  G NSAG+  GGG G+ LA W++HG P +++   D++RF  +L 
Sbjct: 366 RCIMGESPAVQGYFVLAGMNSAGLSFGGGAGKYLAEWMVHGYPSENVWELDLKRF-GALQ 424

Query: 451 DHPRWIRERSHESYAKNYSVVFPHDEPLAGRNMRRDPLHEELLGQGCVFQERHGWERPGW 510
               ++R R  E     Y +  P  +   GR +R  PL++ L  QG  + E+HG+ERP +
Sbjct: 425 SSRTFLRHRVMEVMPLMYDLKVPRWDFQTGRQLRTSPLYDRLDAQGARWMEKHGFERPKY 484

Query: 511 FHPRGPAPVLEYDYYGAYGSRAHEDYAYRRLLADEY--TFAFPPHHDTIKKECLACRGAA 568
           F P                         + LLA E   TF  P   D ++ E   C+ A 
Sbjct: 485 FVPPD-----------------------KDLLALEQSKTFYKPDWFDIVESEVKCCKEAV 521

Query: 569 AVFDMSYFGKFYL--VGLDARKAADWLFSADVSRPPGSTVYTCMLNHRGGTESDLTVSRL 626
            V DMS F KF +   G  A +   +LFS D+  P G  V+T MLN  GG E+D +++RL
Sbjct: 522 CVIDMSSFTKFEITSTGDQALEVLQYLFSNDLDVPVGHIVHTGMLNEGGGYENDCSIARL 581

Query: 627 APSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHITTVLQDQKSQCQLIDSSEDLGMISIQ 686
                            +++        H W+ +   +  + S   L D +     +++ 
Sbjct: 582 -------------NKRSFFMISPTDQQVHCWAWLKKHM-PKDSNLLLEDVTWKYTALNLI 627

Query: 687 GPASRAILQEVLDADLSNEAFPFSTHKLLRAA-GHLVRAMRLSFVGELGWELHIPKASCV 745
           GP +  +L E+  A ++ + FP    K +     + +R M ++  GE G+ L+IP    +
Sbjct: 628 GPRAVDVLSELSYAPMTPDHFPSLFCKEMSVGYANGIRVMSMTHTGEPGFMLYIPIEYAL 687

Query: 746 PVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHWHADLRPDDSPLEAGLAFTCKLKSPV 805
            VY  VM+ G K+G+ NAGY A+ SL IEK +  W  D+    +PLE G     KL+  +
Sbjct: 688 HVYNEVMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDINNLTTPLECGRESRVKLEKGM 747

Query: 806 PFLGREALEQQRAAGLRRRLVCFTMEDK------VPMFGLEAIWRNGQVVGHVRRADFGF 859
            F+GR+AL QQ+  G+ +RL  F ++D        P +G E I+RNGQ VG    + + +
Sbjct: 748 DFIGRDALLQQKQNGVYKRLTMFILDDHDSDLDLWPWWG-EPIYRNGQYVGKTTSSAYSY 806

Query: 860 AIDKTIAYGYIHDPSGGP-----VSLDFVKSGDYALERMGVTYGAQAHL 903
           ++++ +  G++H+ S        V+ DF+  G+Y ++  G  + A+A L
Sbjct: 807 SLERHVCLGFVHNFSEDTGEEQVVTADFINRGEYEIDIAGYRFQAKAKL 855


>gi|44662838 aminomethyltransferase [Homo sapiens]
          Length = 403

 Score = 70.5 bits (171), Expect = 7e-12
 Identities = 85/371 (22%), Positives = 149/371 (40%), Gaps = 45/371 (12%)

Query: 553 HHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFSADVSR-PPGSTVYTCML 611
           + D+     L  R   ++FD+S+  +  ++G D  K  + L   D++   P     +   
Sbjct: 61  YRDSHTDSHLHTRQHCSLFDVSHMLQTKILGSDRVKLMESLVVGDIAELRPNQGTLSLFT 120

Query: 612 NHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHITTVLQDQKSQC 671
           N  GG   DL V+  +            EG  Y ++  G      W     ++QD+  + 
Sbjct: 121 NEAGGILDDLIVTNTS------------EGHLYVVSNAGC-----WEKDLALMQDKVREL 163

Query: 672 QLIDSSEDLGM-------ISIQGPASRAILQEVLDADLSNEAFPFSTHKLLRAAGHL-VR 723
           Q  +   D+G+       +++QGP +  +LQ  +  DL     PF T  ++   G    R
Sbjct: 164 Q--NQGRDVGLEVLDNALLALQGPTAAQVLQAGVADDLRK--LPFMTSAVMEVFGVSGCR 219

Query: 724 AMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLIN-AGYRAIDSLSIEKGYRHWHA 782
             R  + GE G E+ +P A  V +  A++    K+  +  AG  A DSL +E G   +  
Sbjct: 220 VTRCGYTGEDGVEISVPVAGAVHLATAIL----KNPEVKLAGLAARDSLRLEAGLCLYGN 275

Query: 783 DLRPDDSPLEAGLAFTC--KLKSPVPFLGREALEQQRAAGLRRRLVCFTMEDKVPMFGLE 840
           D+    +P+E  L++T   + ++ + F G + +  Q    ++RR V    E         
Sbjct: 276 DIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEGAPMRAHSP 335

Query: 841 AIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMGVTYGAQ 900
            +   G  +G V       ++ K +A GY        V  ++ + G   L  +       
Sbjct: 336 ILNMEGTKIGTVTSGCPSPSLKKNVAMGY--------VPCEYSRPGTMLLVEVRRKQQMA 387

Query: 901 AHLKSPFDPNN 911
              K PF P N
Sbjct: 388 VVSKMPFVPTN 398


>gi|8923708 FAD-dependent oxidoreductase domain containing 1 [Homo
           sapiens]
          Length = 486

 Score = 60.5 bits (145), Expect = 7e-09
 Identities = 95/429 (22%), Positives = 173/429 (40%), Gaps = 46/429 (10%)

Query: 57  QGPSRPLPSTANVVVIGGGSLGCQTLYHLAKL----GMSGAVLLERERLTS--GTTWHTA 110
           Q  S   P  ++VV++GGG LG    Y L KL    G    +++ER+   S   T     
Sbjct: 54  QDTSHLPPEHSDVVIVGGGVLGLSVAYWLKKLESRRGAIRVLVVERDHTYSQASTGLSVG 113

Query: 111 GLLWQLR-PSDVEVELL-AHTRRVVSRELE--EETGLHTGWIQNGGLFIASNRQRLDEYK 166
           G+  Q   P ++++ L  A   R ++  L   +   L   +  +G L +AS +      +
Sbjct: 114 GICQQFSLPENIQLSLFSASFLRNINEYLAVVDAPPLDLRFNPSGYLLLASEKDAA-AME 172

Query: 167 RLMSLGKAYGVESHVLSPAETKTLYPLMNVDDLYGTLYVPHD-GTMDPAGTCTTLARAAS 225
             + + +  G +  ++SP + +  +P +N + +    Y   D G  DP      L R   
Sbjct: 173 SNVKVQRQEGAKVSLMSPDQLRNKFPWINTEGVALASYGMEDEGWFDPWCLLQGLRRKVQ 232

Query: 226 ARGA-----QVIENCPVTGIRVWTDDFGV--RRVAGVET------QHGSIQTPCVVNCAG 272
           + G      +V      +   + TDD  V  +R+  V        ++  ++   V+N AG
Sbjct: 233 SLGVLFCQGEVTRFVSSSQRMLTTDDKAVVLKRIHEVHVKMDRSLEYQPVECAIVINAAG 292

Query: 273 VWASAVGRMAGV-----------KVPLVAMHHAYVVTERIEGIQ-NMPNVRDHDASVYLR 320
            W++ +  +AGV           K+P+        V    +G     P V D   + + R
Sbjct: 293 AWSAQIAALAGVGEGPPGTLQGTKLPVEPRKRYVYVWHCPQGPGLETPLVADTSGAYFRR 352

Query: 321 LQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWEVFTQHIEGAIN-RVPVLEKTGIKST 379
               +  +GG   +P   EE          ++D + F   +   +  RVP  E   ++S 
Sbjct: 353 EGLGSNYLGG--RSPTEQEEPDP----ANLEVDHDFFQDKVWPHLALRVPAFETLKVQSA 406

Query: 380 VCGPESF-TPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGCGQELAHWIIHGRPEK-DM 437
             G   + T D   ++G  P +   +   GF+  G+    G G+ +A  ++ GR +  D+
Sbjct: 407 WAGYYDYNTFDQNGVVGPHPLVVNMYFATGFSGHGLQQAPGIGRAVAEMVLKGRFQTIDL 466

Query: 438 HGYDIRRFH 446
             +   RF+
Sbjct: 467 SPFLFTRFY 475


>gi|13376331 L-2-hydroxyglutarate dehydrogenase precursor [Homo
           sapiens]
          Length = 463

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 59/258 (22%), Positives = 110/258 (42%), Gaps = 36/258 (13%)

Query: 51  GTSVVAQGPSRPL--------PSTANVVVIGGGSLGCQTLYHLAKLGMSGAV-LLERER- 100
           G    A G  RPL         S+ ++V++GGG +G  +   L     S ++ +LE+E+ 
Sbjct: 25  GACGFASGRPRPLCGGSRSASTSSFDIVIVGGGIVGLASARALILRHPSLSIGVLEKEKD 84

Query: 101 LTSGTTWHTAGLLWQ---LRPSDVEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIAS 157
           L    T H +G++      +P  ++ +L      ++  E  ++ G+   + Q G L +A 
Sbjct: 85  LAVHQTGHNSGVIHSGIYYKPESLKAKLCVQGAALLY-EYCQQKGI--SYKQCGKLIVAV 141

Query: 158 NRQRLDEYKRLMSLGKAYGVES-HVLSPAETKTLYP----LMNVDDLYGTLYVPHDGTMD 212
            ++ +   + L   G   GV    ++   + K   P    LM +D        PH G +D
Sbjct: 142 EQEEIPRLQALYEKGLQNGVPGLRLIQQEDIKKKEPYCRGLMAID-------CPHTGIVD 194

Query: 213 PAGTCTTLARAASARGAQVIENCPVTGIRVWTDDFGVRRVAGVE-------TQHGSIQTP 265
                 + A+     G  V+ N  V GI +   +   R + G++       T+   I+  
Sbjct: 195 YRQVALSFAQDFQEAGGSVLTNFEVKGIEM-AKESPSRSIDGMQYPIVIKNTKGEEIRCQ 253

Query: 266 CVVNCAGVWASAVGRMAG 283
            VV CAG+++  +  ++G
Sbjct: 254 YVVTCAGLYSDRISELSG 271


>gi|60499001 pipecolic acid oxidase [Homo sapiens]
          Length = 390

 Score = 38.9 bits (89), Expect = 0.022
 Identities = 54/223 (24%), Positives = 93/223 (41%), Gaps = 14/223 (6%)

Query: 68  NVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERL--TSGTTWHTAGLLWQLRPSDVEVEL 125
           + +VIG G  GC T YHLAK      +LLE+  L  + G++   + ++ +    D    +
Sbjct: 9   DAIVIGAGIQGCFTAYHLAK-HRKRILLLEQFFLPHSRGSSHGQSRIIRKAYLEDFYTRM 67

Query: 126 LAHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPA 185
           + H    +  +LE E G  T   +  GL +   ++   E K + +      VE   LS  
Sbjct: 68  M-HECYQIWAQLEHEAG--TQLHRQTGLLLLGMKEN-QELKTIQANLSRQRVEHQCLSSE 123

Query: 186 ETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTD 245
           E K  +P  N+    G +     G +D +G      +A  A    + +   +        
Sbjct: 124 ELKQRFP--NIRLPRGEV-----GLLDNSGGVIYAYKALRALQDAIRQLGGIVRDGEKVV 176

Query: 246 DFGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPL 288
           +     +  V+T   S Q   +V  AG W + + R  G+++PL
Sbjct: 177 EINPGLLVTVKTTSRSYQAKSLVITAGPWTNQLLRPLGIEMPL 219


>gi|239753433 PREDICTED: hypothetical protein XP_002345652 [Homo
           sapiens]
          Length = 302

 Score = 32.3 bits (72), Expect = 2.1
 Identities = 33/98 (33%), Positives = 45/98 (45%), Gaps = 5/98 (5%)

Query: 56  AQGP-SRPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLW 114
           A GP + P+P+ A   +IGG       L  L  LG+   V+L RERL+      T G L 
Sbjct: 47  ATGPLAVPIPAPAPAALIGGSQKVLVILVGLLLLGID-IVILSRERLSKAPP--TPGALS 103

Query: 115 QLRPSDVEVELLAHTRRVVSRELEEETG-LHTGWIQNG 151
              P  +  E    T    ++ L E+TG + T W Q G
Sbjct: 104 SPLPQLLLAEQEPGTPSSTAQGLWEKTGHVITSWPQAG 141


>gi|112382257 InaD-like [Homo sapiens]
          Length = 1801

 Score = 32.0 bits (71), Expect = 2.7
 Identities = 42/174 (24%), Positives = 77/174 (44%), Gaps = 14/174 (8%)

Query: 615 GGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSH-ITTVLQDQKSQCQL 673
           GG  S + V  + P   A        GD + L +GG   Q   S  +  VL++  +  ++
Sbjct: 264 GGKTSGVVVRTIVPGGLADRDGRLQTGD-HILKIGGTNVQGMTSEQVAQVLRNCGNSVRM 322

Query: 674 IDSSEDLGMISIQGPASRAI---LQEVLDADLSNEAFPFSTH--KLLRAAGHLVRAMRLS 728
           + + +  G IS+  PA  A+   L  V      +++  F T+  +L+R  G   +++ + 
Sbjct: 323 LVARDPAGDISVTPPAPAALPVALPTVASKGPGSDSSLFETYNVELVRKDG---QSLGIR 379

Query: 729 FVGELGWELHIPKASCVPVYRAVMAAGAKHG---LINAGYRAIDSLSIEKGYRH 779
            VG +G   H  +AS + V   +  + A H     +N    A+D ++I+    H
Sbjct: 380 IVGYVGTS-HTGEASGIYVKSIIPGSAAYHNGHIQVNDKIVAVDGVNIQGFANH 432


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
           [Homo sapiens]
          Length = 2004

 Score = 32.0 bits (71), Expect = 2.7
 Identities = 27/67 (40%), Positives = 32/67 (47%), Gaps = 10/67 (14%)

Query: 81  TLYHLAKLGMSGA--VLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHT-----RRVV 133
           TL+HL  L       V++ RE+L      H A L   LRP DV+ E L  T       VV
Sbjct: 730 TLHHLRMLDFRSDQFVIIRREKLIQD---HMAKLQLNLRPVDVDPECLRWTPVIVSNSVV 786

Query: 134 SRELEEE 140
           S E EEE
Sbjct: 787 SEEEEEE 793


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
           [Homo sapiens]
          Length = 2004

 Score = 32.0 bits (71), Expect = 2.7
 Identities = 27/67 (40%), Positives = 32/67 (47%), Gaps = 10/67 (14%)

Query: 81  TLYHLAKLGMSGA--VLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHT-----RRVV 133
           TL+HL  L       V++ RE+L      H A L   LRP DV+ E L  T       VV
Sbjct: 730 TLHHLRMLDFRSDQFVIIRREKLIQD---HMAKLQLNLRPVDVDPECLRWTPVIVSNSVV 786

Query: 134 SRELEEE 140
           S E EEE
Sbjct: 787 SEEEEEE 793


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
           [Homo sapiens]
          Length = 2004

 Score = 32.0 bits (71), Expect = 2.7
 Identities = 27/67 (40%), Positives = 32/67 (47%), Gaps = 10/67 (14%)

Query: 81  TLYHLAKLGMSGA--VLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHT-----RRVV 133
           TL+HL  L       V++ RE+L      H A L   LRP DV+ E L  T       VV
Sbjct: 730 TLHHLRMLDFRSDQFVIIRREKLIQD---HMAKLQLNLRPVDVDPECLRWTPVIVSNSVV 786

Query: 134 SRELEEE 140
           S E EEE
Sbjct: 787 SEEEEEE 793


>gi|8923900 cytidine monophospho-N-acetylneuraminic acid synthetase
           [Homo sapiens]
          Length = 434

 Score = 31.2 bits (69), Expect = 4.6
 Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 25/106 (23%)

Query: 1   MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPS 60
           M S+ +    + ++PR  P+RG  P                 QR  + GQG     +G  
Sbjct: 1   MDSVEKGAATSVSNPRGRPSRGRPP---------------KLQRNSRGGQG-----RGVE 40

Query: 61  RPLPSTANVVVIGGGSLG--CQTLYHLAKLGMSGAVLLERERLTSG 104
           +P P  A +++  GGS G   + + HLA + + G VL  R  L SG
Sbjct: 41  KP-PHLAALILARGGSKGIPLKNIKHLAGVPLIGWVL--RAALDSG 83


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 31.2 bits (69), Expect = 4.6
 Identities = 17/64 (26%), Positives = 31/64 (48%), Gaps = 4/64 (6%)

Query: 14  HPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPSRPLPSTANVVVIG 73
           HP   P +  GP    ++  P ++ ++PY  +    QG    +  PS+P+ +  ++ V  
Sbjct: 686 HP---PLQSAGPSEQVNSKAPLSKSALPYS-SFSSDQGLGESSAAPSQPITAVKDMPVRS 741

Query: 74  GGSL 77
           GG L
Sbjct: 742 GGLL 745


>gi|53988380 mesothelin isoform 2 preproprotein [Homo sapiens]
          Length = 630

 Score = 30.8 bits (68), Expect = 6.1
 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 7/80 (8%)

Query: 46  LKEGQGTSVVAQGPSRPLPSTANVV---VIGGGSLGCQTLYHLAKLGMSGAVLLERERLT 102
           L+  +G  +  Q P RPLP  A ++   V G G L   TL  L          L  E L+
Sbjct: 399 LEVNKGHEMSPQAPRRPLPQVATLIDRFVKGRGQLDKDTLDTLTAFYPGYLCSLSPEELS 458

Query: 103 SGTTWHTAGLLWQLRPSDVE 122
           S         +W +RP D++
Sbjct: 459 S----VPPSSIWAVRPQDLD 474


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,568,574
Number of Sequences: 37866
Number of extensions: 1797608
Number of successful extensions: 3565
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 3528
Number of HSP's gapped (non-prelim): 21
length of query: 918
length of database: 18,247,518
effective HSP length: 111
effective length of query: 807
effective length of database: 14,044,392
effective search space: 11333824344
effective search space used: 11333824344
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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