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Search of human proteins with 197209857
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|197209857 adaptor-related protein complex 3, mu 2 subunit
[Homo sapiens]
(418 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|197209857 adaptor-related protein complex 3, mu 2 subunit [Ho... 840 0.0
gi|5803000 adaptor-related protein complex 3, mu 2 subunit [Homo... 840 0.0
gi|6912240 adaptor-related protein complex 3, mu 1 subunit [Homo... 741 0.0
gi|46370095 adaptor-related protein complex 3, mu 1 subunit [Hom... 741 0.0
gi|9506797 adaptor-related protein complex 1, mu 2 subunit [Homo... 191 1e-48
gi|14210504 adaptor-related protein complex 1, mu 1 subunit isof... 175 6e-44
gi|194473724 adaptor-related protein complex 1, mu 1 subunit iso... 166 3e-41
gi|14917109 adaptor-related protein complex 2, mu 1 subunit isof... 157 1e-38
gi|68799814 adaptor-related protein complex 2, mu 1 subunit isof... 156 3e-38
gi|14917111 adaptor-related protein complex 4, mu 1 subunit [Hom... 104 1e-22
gi|88703051 adaptor-related protein complex 1, sigma 3 subunit [... 38 0.015
gi|22027655 adaptor-related protein complex 1 sigma 2 subunit [H... 36 0.057
gi|189409104 adaptor-related protein complex 4, sigma 1 subunit ... 36 0.057
gi|4557471 adaptor-related protein complex 1, sigma 1 subunit [H... 35 0.13
gi|4757768 Rho GDP dissociation inhibitor (GDI) alpha [Homo sapi... 32 1.4
gi|26787993 stonin 1 [Homo sapiens] 31 2.4
gi|29553944 STON1-GTF2A1L protein [Homo sapiens] 31 2.4
gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens] 30 3.1
gi|5174729 TSC22 domain family, member 1 isoform 2 [Homo sapiens] 30 3.1
gi|4502861 adaptor-related protein complex 3, sigma 1 subunit [H... 30 4.1
gi|70906430 adaptor-related protein complex 2, sigma 1 subunit i... 30 5.3
gi|116235472 SH3-domain GRB2-like (endophilin) interacting prote... 29 9.1
>gi|197209857 adaptor-related protein complex 3, mu 2 subunit [Homo
sapiens]
Length = 418
Score = 840 bits (2170), Expect = 0.0
Identities = 418/418 (100%), Positives = 418/418 (100%)
Query: 1 MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVY 60
MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVY
Sbjct: 1 MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVY 60
Query: 61 RHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNG 120
RHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNG
Sbjct: 61 RHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNG 120
Query: 121 FPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAY 180
FPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAY
Sbjct: 121 FPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAY 180
Query: 181 FDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFK 240
FDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFK
Sbjct: 181 FDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFK 240
Query: 241 RWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNISFRDSSSLGRFEITVGPKQT 300
RWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNISFRDSSSLGRFEITVGPKQT
Sbjct: 241 RWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNISFRDSSSLGRFEITVGPKQT 300
Query: 301 MGKTIEGVTVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMSL 360
MGKTIEGVTVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMSL
Sbjct: 301 MGKTIEGVTVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMSL 360
Query: 361 QAGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQVRT 418
QAGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQVRT
Sbjct: 361 QAGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQVRT 418
>gi|5803000 adaptor-related protein complex 3, mu 2 subunit [Homo
sapiens]
Length = 418
Score = 840 bits (2170), Expect = 0.0
Identities = 418/418 (100%), Positives = 418/418 (100%)
Query: 1 MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVY 60
MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVY
Sbjct: 1 MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVY 60
Query: 61 RHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNG 120
RHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNG
Sbjct: 61 RHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNG 120
Query: 121 FPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAY 180
FPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAY
Sbjct: 121 FPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAY 180
Query: 181 FDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFK 240
FDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFK
Sbjct: 181 FDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFK 240
Query: 241 RWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNISFRDSSSLGRFEITVGPKQT 300
RWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNISFRDSSSLGRFEITVGPKQT
Sbjct: 241 RWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNISFRDSSSLGRFEITVGPKQT 300
Query: 301 MGKTIEGVTVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMSL 360
MGKTIEGVTVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMSL
Sbjct: 301 MGKTIEGVTVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMSL 360
Query: 361 QAGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQVRT 418
QAGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQVRT
Sbjct: 361 QAGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQVRT 418
>gi|6912240 adaptor-related protein complex 3, mu 1 subunit [Homo
sapiens]
Length = 418
Score = 741 bits (1914), Expect = 0.0
Identities = 352/418 (84%), Positives = 396/418 (94%)
Query: 1 MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVY 60
MIHSLFLIN SGDIFLEKHWKSVVS+SVCDYFFEAQE+A + ENVPPVI TPHHYL+S+Y
Sbjct: 1 MIHSLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIY 60
Query: 61 RHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNG 120
R K+FFV+VIQTEVPPLFVIEFLHRV DTFQDYFG CSE IKDNVV+VYE+LEEMLDNG
Sbjct: 61 RDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNG 120
Query: 121 FPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAY 180
FPLATESNILKELIKPPTILR+VVN+ITGS+NVGD LPTGQLS +PWRR GVKYTNNEAY
Sbjct: 121 FPLATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLSNIPWRRAGVKYTNNEAY 180
Query: 181 FDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFK 240
FDV+EEIDAIIDKSGST+ AEIQGVIDAC+KL+GMPDL+LSFMNPRLLDDVSFHPC+RFK
Sbjct: 181 FDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDLSLSFMNPRLLDDVSFHPCIRFK 240
Query: 241 RWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNISFRDSSSLGRFEITVGPKQT 300
RWESER+LSFIPPDGNFRL+SY VS+QNLVAIPVYVKH+ISF+++SS GRF+IT+GPKQ
Sbjct: 241 RWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHSISFKENSSCGRFDITIGPKQN 300
Query: 301 MGKTIEGVTVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMSL 360
MGKTIEG+TVT MPK VLNM+LTP+QG++TFDPVTK+L+WDVGKI PQKLPSLKG ++L
Sbjct: 301 MGKTIEGITVTVHMPKVVLNMNLTPTQGSYTFDPVTKVLTWDVGKITPQKLPSLKGLVNL 360
Query: 361 QAGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQVRT 418
Q+GA KP+ENP++N+QFKIQQLAISGLKVNRLDMYGEKYKPFKG+KY+TKAGKFQVRT
Sbjct: 361 QSGAPKPEENPSLNIQFKIQQLAISGLKVNRLDMYGEKYKPFKGVKYVTKAGKFQVRT 418
>gi|46370095 adaptor-related protein complex 3, mu 1 subunit [Homo
sapiens]
Length = 418
Score = 741 bits (1914), Expect = 0.0
Identities = 352/418 (84%), Positives = 396/418 (94%)
Query: 1 MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVY 60
MIHSLFLIN SGDIFLEKHWKSVVS+SVCDYFFEAQE+A + ENVPPVI TPHHYL+S+Y
Sbjct: 1 MIHSLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIY 60
Query: 61 RHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNG 120
R K+FFV+VIQTEVPPLFVIEFLHRV DTFQDYFG CSE IKDNVV+VYE+LEEMLDNG
Sbjct: 61 RDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNG 120
Query: 121 FPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAY 180
FPLATESNILKELIKPPTILR+VVN+ITGS+NVGD LPTGQLS +PWRR GVKYTNNEAY
Sbjct: 121 FPLATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLSNIPWRRAGVKYTNNEAY 180
Query: 181 FDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFK 240
FDV+EEIDAIIDKSGST+ AEIQGVIDAC+KL+GMPDL+LSFMNPRLLDDVSFHPC+RFK
Sbjct: 181 FDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDLSLSFMNPRLLDDVSFHPCIRFK 240
Query: 241 RWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNISFRDSSSLGRFEITVGPKQT 300
RWESER+LSFIPPDGNFRL+SY VS+QNLVAIPVYVKH+ISF+++SS GRF+IT+GPKQ
Sbjct: 241 RWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHSISFKENSSCGRFDITIGPKQN 300
Query: 301 MGKTIEGVTVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMSL 360
MGKTIEG+TVT MPK VLNM+LTP+QG++TFDPVTK+L+WDVGKI PQKLPSLKG ++L
Sbjct: 301 MGKTIEGITVTVHMPKVVLNMNLTPTQGSYTFDPVTKVLTWDVGKITPQKLPSLKGLVNL 360
Query: 361 QAGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQVRT 418
Q+GA KP+ENP++N+QFKIQQLAISGLKVNRLDMYGEKYKPFKG+KY+TKAGKFQVRT
Sbjct: 361 QSGAPKPEENPSLNIQFKIQQLAISGLKVNRLDMYGEKYKPFKGVKYVTKAGKFQVRT 418
>gi|9506797 adaptor-related protein complex 1, mu 2 subunit [Homo
sapiens]
Length = 423
Score = 191 bits (484), Expect = 1e-48
Identities = 125/434 (28%), Positives = 220/434 (50%), Gaps = 35/434 (8%)
Query: 4 SLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVYRHK 63
++F+++ G + +++K V+ S ++F + E + P++ + L +
Sbjct: 5 AVFILDVKGKPLISRNYKGDVAMSKIEHFMPLLVQREEEGALAPLLSHGQVHFLWIKHSN 64
Query: 64 IFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPL 123
++ VA V FL++ ++ F +YF E I+DN V+VYE+L+E++D GFP
Sbjct: 65 LYLVATTSKNANASLVYSFLYKTIEVFCEYFKELEEESIRDNFVIVYELLDELMDFGFPQ 124
Query: 124 ATESNILKELIKPPTILRTVVNTI-TGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAYFD 182
T+S IL+E I + N + TG + V P + V WR G+KY NE + D
Sbjct: 125 TTDSKILQEYITQQS------NKLETGKSRV----PPTVTNAVSWRSEGIKYKKNEVFID 174
Query: 183 VIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRL--------------L 228
VIE ++ +++ +GS + +EI G I V L+GMP+L L +N R+ L
Sbjct: 175 VIESVNLLVNANGSVLLSEIVGTIKLKVFLSGMPELRLG-LNDRVLFELTGRSKNKSVEL 233
Query: 229 DDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNISFRDSSSL 288
+DV FH CVR R++++R +SFIPPDG+F L+SY +S Q V ++++ S + S
Sbjct: 234 EDVKFHQCVRLSRFDNDRTISFIPPDGDFELMSYRLSTQ--VKPLIWIE---SVIEKFSH 288
Query: 289 GRFEITVGPKQTMGK--TIEGVTVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDVGKI 346
R EI V K K GV ++ +P + S G+ + P ++ W +
Sbjct: 289 SRVEIMVKAKGQFKKQSVANGVEISVPVPSDADSPRFKTSVGSAKYVPERNVVIWSIKSF 348
Query: 347 NPQKLPSLKGTMSLQAGASKPDE-NPTINLQFKIQQLAISGLKVNRLDMYGEK-YKPFKG 404
K ++ L + + E P I ++F+I +SG++V + + + Y+
Sbjct: 349 PGGKEYLMRAHFGLPSVEKEEVEGRPPIGVKFEIPYFTVSGIQVRYMKIIEKSGYQALPW 408
Query: 405 IKYMTKAGKFQVRT 418
++Y+T++G +Q+RT
Sbjct: 409 VRYITQSGDYQLRT 422
>gi|14210504 adaptor-related protein complex 1, mu 1 subunit isoform
2 [Homo sapiens]
Length = 423
Score = 175 bits (444), Expect = 6e-44
Identities = 115/437 (26%), Positives = 207/437 (47%), Gaps = 41/437 (9%)
Query: 4 SLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVYRHK 63
++++++ G + + ++++ V S ++F E + P++ + + +
Sbjct: 5 AVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNN 64
Query: 64 IFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPL 123
++ VA + V FL++VV F +YF E I+DN V++YE+L+E++D G+P
Sbjct: 65 LYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQ 124
Query: 124 ATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQ-------LSVVPWRRTGVKYTN 176
T+S IL+E I T G +L TG + V WR G+KY
Sbjct: 125 TTDSKILQEYI----------------TQEGHKLETGAPRPPATVTNAVSWRSEGIKYRK 168
Query: 177 NEAYFDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRL--------- 227
NE + DVIE ++ ++ +G+ + +EI G I V L+GMP+L L + L
Sbjct: 169 NEVFLDVIESVNLLVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGKS 228
Query: 228 ----LDDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNISFR 283
L+DV FH CVR R+E++R +SFIPPDG F L+SY + N P+ ++ +
Sbjct: 229 KSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRL---NTHVKPLIWIESVIEK 285
Query: 284 DSSSLGRFEITVGPKQTMGKTIEGVTVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDV 343
S S + I + T V + +P + + G+ + P + W +
Sbjct: 286 HSHSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSI 345
Query: 344 GKINPQKLPSLKGTMSLQAGASKPDE-NPTINLQFKIQQLAISGLKVNRLDMYGEK-YKP 401
K ++ L + ++ E P I+++F+I SG++V L + + Y+
Sbjct: 346 KSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQA 405
Query: 402 FKGIKYMTKAGKFQVRT 418
++Y+T+ G +Q+RT
Sbjct: 406 LPWVRYITQNGDYQLRT 422
>gi|194473724 adaptor-related protein complex 1, mu 1 subunit
isoform 1 [Homo sapiens]
Length = 435
Score = 166 bits (421), Expect = 3e-41
Identities = 115/449 (25%), Positives = 207/449 (46%), Gaps = 53/449 (11%)
Query: 4 SLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVYRHK 63
++++++ G + + ++++ V S ++F E + P++ + + +
Sbjct: 5 AVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNN 64
Query: 64 IFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPL 123
++ VA + V FL++VV F +YF E I+DN V++YE+L+E++D G+P
Sbjct: 65 LYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQ 124
Query: 124 ATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQ-------LSVVPWRRTGVKYTN 176
T+S IL+E I T G +L TG + V WR G+KY
Sbjct: 125 TTDSKILQEYI----------------TQEGHKLETGAPRPPATVTNAVSWRSEGIKYRK 168
Query: 177 NEAYFDVIEEIDAI------------IDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMN 224
NE + DVIE ++ + + +G+ + +EI G I V L+GMP+L L +
Sbjct: 169 NEVFLDVIESVNLLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLND 228
Query: 225 PRL-------------LDDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVA 271
L L+DV FH CVR R+E++R +SFIPPDG F L+SY + N
Sbjct: 229 KVLFDNTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRL---NTHV 285
Query: 272 IPVYVKHNISFRDSSSLGRFEITVGPKQTMGKTIEGVTVTSQMPKGVLNMSLTPSQGTHT 331
P+ ++ + S S + I + T V + +P + + G+
Sbjct: 286 KPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVK 345
Query: 332 FDPVTKMLSWDVGKINPQKLPSLKGTMSLQAGASKPDE-NPTINLQFKIQQLAISGLKVN 390
+ P + W + K ++ L + ++ E P I+++F+I SG++V
Sbjct: 346 WVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVR 405
Query: 391 RLDMYGEK-YKPFKGIKYMTKAGKFQVRT 418
L + + Y+ ++Y+T+ G +Q+RT
Sbjct: 406 YLKIIEKSGYQALPWVRYITQNGDYQLRT 434
>gi|14917109 adaptor-related protein complex 2, mu 1 subunit isoform
a [Homo sapiens]
Length = 435
Score = 157 bits (398), Expect = 1e-38
Identities = 117/447 (26%), Positives = 202/447 (45%), Gaps = 43/447 (9%)
Query: 1 MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVY 60
MI LF+ N G++ + + ++ + R+ D F A + PV V
Sbjct: 1 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVR-SPVTNIARTSFFHVK 59
Query: 61 RHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNG 120
R I+ AV + V V EFL+++ D YFG SE IK+N V++YE+L+E+LD G
Sbjct: 60 RSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFG 119
Query: 121 FPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAY 180
+P +E+ LK I I ++ T + + Q+ TGQ+ WRR G+KY NE +
Sbjct: 120 YPQNSETGALKTFITQQGI-KSQHQTKEEQSQITSQV-TGQIG---WRREGIKYRRNELF 174
Query: 181 FDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRL------------- 227
DV+E ++ ++ G ++A + G + L+GMP+ MN ++
Sbjct: 175 LDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFG-MNDKIVIEKQGKGTADET 233
Query: 228 ---------LDDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKH 278
+DD +FH CVR +++SER +SFIPPDG F L+ Y + ++ V
Sbjct: 234 SKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRV---- 289
Query: 279 NISFRDSSSLGRFEITVGPKQTMGKTI--EGVTVTSQMPKGVLNMSLTPSQGTHTFDPVT 336
I + E+ V K ++ + + V P + + +G +
Sbjct: 290 -IPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASE 348
Query: 337 KMLSWDVGKINPQKLPSLKGTMS-LQAGASKPDENPTINLQFKIQQLAISGLKVNRLDMY 395
+ W + ++ K + + L K P I++ F++ A SGLKV L ++
Sbjct: 349 NAIVWKIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEV-PFAPSGLKVRYLKVF 407
Query: 396 GEK-----YKPFKGIKYMTKAGKFQVR 417
K + K ++Y+ ++G ++ R
Sbjct: 408 EPKLNYSDHDVIKWVRYIGRSGIYETR 434
>gi|68799814 adaptor-related protein complex 2, mu 1 subunit isoform
b [Homo sapiens]
Length = 433
Score = 156 bits (395), Expect = 3e-38
Identities = 117/447 (26%), Positives = 200/447 (44%), Gaps = 45/447 (10%)
Query: 1 MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVY 60
MI LF+ N G++ + + ++ + R+ D F A + PV V
Sbjct: 1 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVR-SPVTNIARTSFFHVK 59
Query: 61 RHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNG 120
R I+ AV + V V EFL+++ D YFG SE IK+N V++YE+L+E+LD G
Sbjct: 60 RSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFG 119
Query: 121 FPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAY 180
+P +E+ LK I I T + + Q+ TGQ+ WRR G+KY NE +
Sbjct: 120 YPQNSETGALKTFITQQGIKS---QTKEEQSQITSQV-TGQIG---WRREGIKYRRNELF 172
Query: 181 FDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRL------------- 227
DV+E ++ ++ G ++A + G + L+GMP+ MN ++
Sbjct: 173 LDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFG-MNDKIVIEKQGKGTADET 231
Query: 228 ---------LDDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKH 278
+DD +FH CVR +++SER +SFIPPDG F L+ Y + ++ V
Sbjct: 232 SKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRV---- 287
Query: 279 NISFRDSSSLGRFEITVGPKQTMGKTI--EGVTVTSQMPKGVLNMSLTPSQGTHTFDPVT 336
I + E+ V K ++ + + V P + + +G +
Sbjct: 288 -IPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASE 346
Query: 337 KMLSWDVGKINPQKLPSLKGTMS-LQAGASKPDENPTINLQFKIQQLAISGLKVNRLDMY 395
+ W + ++ K + + L K P I++ F++ A SGLKV L ++
Sbjct: 347 NAIVWKIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEV-PFAPSGLKVRYLKVF 405
Query: 396 GEK-----YKPFKGIKYMTKAGKFQVR 417
K + K ++Y+ ++G ++ R
Sbjct: 406 EPKLNYSDHDVIKWVRYIGRSGIYETR 432
>gi|14917111 adaptor-related protein complex 4, mu 1 subunit [Homo
sapiens]
Length = 453
Score = 104 bits (260), Expect = 1e-22
Identities = 104/457 (22%), Positives = 188/457 (41%), Gaps = 45/457 (9%)
Query: 1 MIHSLFLINSSGDIFLEKHWKSVVS-RSVCDYFFEAQERATEAENVPPVIPTPHHYLLSV 59
MI F+++S GD + K ++ R V + F+ E+ PV+ H
Sbjct: 1 MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDES--PVVMHHHGRHFIH 58
Query: 60 YRHKIFFVAVIQTE-VPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLD 118
RH ++ V +E V P ++E L R+ DY G E I NV +VYE+L+E+LD
Sbjct: 59 IRHSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLD 118
Query: 119 NGFPLATESNILKELIKPPTILR--------TVVNTITGSTNVGDQLPTGQLSVVPWRRT 170
G+ T + +L+ I+ ++ + V T P+ S
Sbjct: 119 YGYVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSR 178
Query: 171 GVKYTNNEAYFDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSF-------- 222
+ NE + DV+E + +I +GS + ++QG I L ++ +
Sbjct: 179 SDQSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCVGK 238
Query: 223 -----MNPRL-LDDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYV 276
P + +D+VSFH V +ES RIL PP G ++ Y +S +P +
Sbjct: 239 SELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQLSDDLPSPLPFRL 298
Query: 277 KHNISFRDSSSLGRFEITVGPKQTMGKTIEGVTVTSQ--MPKGVLNMSLTPSQGTHTFDP 334
++ + S GR ++ + + + + + V +P+GV+++S S +
Sbjct: 299 FPSVQWDRGS--GRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQELSSPEQKAEL 356
Query: 335 VTKMLSWDVGKIN---------PQKLPSLKGTMS--LQAGASKPDENPTINLQFKIQQLA 383
L WD+ ++ +P G S L AS P +L F++ +
Sbjct: 357 AEGALRWDLPRVQGGSQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPA-SLSFELPRHT 415
Query: 384 ISGLKVNRLDMYGE---KYKPFKGIKYMTKAGKFQVR 417
SGL+V L + P K +++++ + + +R
Sbjct: 416 CSGLQVRFLRLAFRPCGNANPHKWVRHLSHSDAYVIR 452
>gi|88703051 adaptor-related protein complex 1, sigma 3 subunit
[Homo sapiens]
Length = 154
Score = 38.1 bits (87), Expect = 0.015
Identities = 35/152 (23%), Positives = 61/152 (40%), Gaps = 21/152 (13%)
Query: 1 MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLS-- 58
MIH + L + G + L+K + ++ + ER + +I + H S
Sbjct: 1 MIHFILLFSRQGKLRLQKWYITLPDK----------ERKKITREIVQIILSRGHRTSSFV 50
Query: 59 -------VYRH--KIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVV 109
VY+ ++F I+ + L +E +HR V+ YFG E I N
Sbjct: 51 DWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKA 110
Query: 110 YEVLEEMLDNGFPLATESNILKELIKPPTILR 141
Y +L+E + G T I + I+ +L+
Sbjct: 111 YFILDEFIIGGEIQETSKKIAVKAIEDSDMLQ 142
>gi|22027655 adaptor-related protein complex 1 sigma 2 subunit [Homo
sapiens]
Length = 157
Score = 36.2 bits (82), Expect = 0.057
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
Query: 64 IFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPL 123
++F I+ + L +E +HR V+ YFG E I N Y +L+E L G
Sbjct: 64 LYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQ 123
Query: 124 AT-ESNILKEL 133
T + N+LK +
Sbjct: 124 ETSKKNVLKAI 134
>gi|189409104 adaptor-related protein complex 4, sigma 1 subunit
isoform 2 [Homo sapiens]
Length = 144
Score = 36.2 bits (82), Expect = 0.057
Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Query: 59 VYRH--KIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEM 116
+YR +F V + + + EF+H V+ +YF SE I N+ V+ +L+EM
Sbjct: 58 IYRQYAALFIVVGVNDTENEMAIYEFIHNFVEVLDEYFSRVSELDIMFNLDKVHIILDEM 117
Query: 117 LDNGFPLAT-ESNILKELI 134
+ NG + T + IL L+
Sbjct: 118 VLNGCIVETNRARILAPLL 136
>gi|4557471 adaptor-related protein complex 1, sigma 1 subunit [Homo
sapiens]
Length = 158
Score = 35.0 bits (79), Expect = 0.13
Identities = 21/78 (26%), Positives = 35/78 (44%)
Query: 64 IFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPL 123
++F I+ + L +E +HR V+ YFG E I N Y +L+E L G
Sbjct: 65 LYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQ 124
Query: 124 ATESNILKELIKPPTILR 141
T + + I+ +L+
Sbjct: 125 DTSKKSVLKAIEQADLLQ 142
>gi|4757768 Rho GDP dissociation inhibitor (GDI) alpha [Homo
sapiens]
Length = 204
Score = 31.6 bits (70), Expect = 1.4
Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 243 ESERILSFIPPDG-NFRL-LSYHVSAQNLVAIPVYVKHNISFRDSSSLGRFEITVGPKQT 300
ES + SF+ +G +R+ +S+ V+ + +V+ Y++H ++R + + + VG
Sbjct: 95 ESFKKQSFVLKEGVEYRIKISFRVNRE-IVSGMKYIQH--TYRKGVKIDKTDYMVGSYGP 151
Query: 301 MGKTIEGVTVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWD 342
+ E +T + PKG+L + T D T LSW+
Sbjct: 152 RAEEYEFLTPVEEAPKGMLARGSYSIKSRFTDDDKTDHLSWE 193
>gi|26787993 stonin 1 [Homo sapiens]
Length = 735
Score = 30.8 bits (68), Expect = 2.4
Identities = 13/34 (38%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
Query: 230 DVSFHPCVRFKRWESERILSFIPPDG-NFRLLSY 262
D FH CV + +E RI+ F+P D F L+ +
Sbjct: 484 DYHFHKCVNVQEFEQSRIIKFVPLDACRFELMRF 517
>gi|29553944 STON1-GTF2A1L protein [Homo sapiens]
Length = 1182
Score = 30.8 bits (68), Expect = 2.4
Identities = 13/34 (38%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
Query: 230 DVSFHPCVRFKRWESERILSFIPPDG-NFRLLSY 262
D FH CV + +E RI+ F+P D F L+ +
Sbjct: 484 DYHFHKCVNVQEFEQSRIIKFVPLDACRFELMRF 517
>gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]
Length = 1073
Score = 30.4 bits (67), Expect = 3.1
Identities = 14/49 (28%), Positives = 27/49 (55%)
Query: 102 IKDNVVVVYEVLEEMLDNGFPLATESNILKELIKPPTILRTVVNTITGS 150
+++ V V+ E ++E+++ L E+N+LK L P + + TGS
Sbjct: 999 VREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQTGS 1047
>gi|5174729 TSC22 domain family, member 1 isoform 2 [Homo sapiens]
Length = 144
Score = 30.4 bits (67), Expect = 3.1
Identities = 14/49 (28%), Positives = 27/49 (55%)
Query: 102 IKDNVVVVYEVLEEMLDNGFPLATESNILKELIKPPTILRTVVNTITGS 150
+++ V V+ E ++E+++ L E+N+LK L P + + TGS
Sbjct: 70 VREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQTGS 118
>gi|4502861 adaptor-related protein complex 3, sigma 1 subunit [Homo
sapiens]
Length = 193
Score = 30.0 bits (66), Expect = 4.1
Identities = 19/72 (26%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Query: 59 VYRH--KIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEM 116
+YRH ++FV + + L +++ + V+T F E + +V V+ +L EM
Sbjct: 64 IYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVHNILAEM 123
Query: 117 LDNGFPLATESN 128
+ G L T N
Sbjct: 124 VMGGMVLETNMN 135
>gi|70906430 adaptor-related protein complex 2, sigma 1 subunit
isoform AP17 [Homo sapiens]
Length = 142
Score = 29.6 bits (65), Expect = 5.3
Identities = 18/72 (25%), Positives = 34/72 (47%), Gaps = 1/72 (1%)
Query: 64 IFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEM-LDNGFP 122
++F + L +E +H V+ +YF E + N VY V++EM L
Sbjct: 65 LYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIR 124
Query: 123 LATESNILKELI 134
+++ +LK+L+
Sbjct: 125 ETSQTKVLKQLL 136
>gi|116235472 SH3-domain GRB2-like (endophilin) interacting protein
1 [Homo sapiens]
Length = 828
Score = 28.9 bits (63), Expect = 9.1
Identities = 41/166 (24%), Positives = 69/166 (41%), Gaps = 18/166 (10%)
Query: 256 NFRLLSYHVSAQNLVAIPVYVKHNISFRDSSSLGRFEITVG-PKQTMGKTIEGVTVTSQM 314
N +L Y VSAQ + + P+ + N SS+ R + T + V +
Sbjct: 670 NVDMLKYQVSAQGIQSTPLNLAVNWRCEPSSTDLRIDYKYNTDAMTTAVALNNVQFLVPI 729
Query: 315 PKGV--LNMSLTPSQGTHTFDPVTKMLSWDVGKINPQK----LPSLKGTMSLQAGASKPD 368
GV L L P+ ++ + + W + I+ + + SL L G SKP
Sbjct: 730 DGGVTKLQAVLPPA----VWNAEQQRILWKIPDISQKSENGGVGSLLARFQLSEGPSKP- 784
Query: 369 ENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKF 414
+P + +QF + +SG + ++ G Y+ F IK AGK+
Sbjct: 785 -SPLV-VQFTSEGSTLSGCDI---ELVGAGYR-FSLIKKRFAAGKY 824
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,394,050
Number of Sequences: 37866
Number of extensions: 662675
Number of successful extensions: 1345
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1306
Number of HSP's gapped (non-prelim): 22
length of query: 418
length of database: 18,247,518
effective HSP length: 105
effective length of query: 313
effective length of database: 14,271,588
effective search space: 4467007044
effective search space used: 4467007044
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.