Search of human proteins with 197116359

Search of human proteins with 197116359

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|197116359 inositol polyphosphate-4-phosphatase, type 1
isoform d [Homo sapiens]
         (977 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|197116359 inositol polyphosphate-4-phosphatase, type 1 isofor...  1966   0.0  
gi|197116361 inositol polyphosphate-4-phosphatase, type 1 isofor...  1947   0.0  
gi|4755140 inositol polyphosphate-4-phosphatase, type 1 isoform ...  1853   0.0  
gi|4504705 inositol polyphosphate-4-phosphatase, type 1 isoform ...  1769   0.0  
gi|156104897 inositol polyphosphate-4-phosphatase, type II, 105k...   734   0.0  
gi|156104895 inositol polyphosphate-4-phosphatase, type II, 105k...   734   0.0  
gi|47578115 DEP domain containing 2 isoform a [Homo sapiens]          123   1e-27
gi|34452732 phosphatidylinositol-3,4,5-trisphosphate-dependent R...   120   8e-27
gi|88703066 copine-like protein [Homo sapiens]                         36   0.15 
gi|25141328 copine 7 isoform a [Homo sapiens]                          35   0.26 
gi|7656993 copine 7 isoform b [Homo sapiens]                           35   0.26 
gi|25141323 copine V [Homo sapiens]                                    35   0.34 
gi|45269137 mitofusin 1 [Homo sapiens]                                 34   0.59 
gi|226498192 atonal homolog 8 [Homo sapiens]                           34   0.76 
gi|126090909 engrailed homeobox 1 [Homo sapiens]                       34   0.76 
gi|25121972 copine VIII [Homo sapiens]                                 34   0.76 
gi|169201827 PREDICTED: similar to hCG1798126 [Homo sapiens]           33   1.00 
gi|169201475 PREDICTED: similar to hCG1798126, partial [Homo sap...    33   1.00 
gi|169190743 PREDICTED: similar to hCG1798126 [Homo sapiens]           33   1.00 
gi|29789058 WW and C2 domain containing 1 isoform 3 [Homo sapiens]     33   1.3  
gi|242247257 WW and C2 domain containing 1 isoform 2 [Homo sapiens]    33   1.3  
gi|242247251 WW and C2 domain containing 1 isoform 1 [Homo sapiens]    33   1.3  
gi|126116565 MYC binding protein 2 [Homo sapiens]                      33   1.3  
gi|34304360 nephrocystin 3 [Homo sapiens]                              33   1.7  
gi|116268109 nucleotide-binding oligomerization domains 27 [Homo...    33   1.7  
gi|28875784 armadillo repeat containing 5 isoform b [Homo sapiens]     32   2.2  
gi|189083768 mitofusin 2 [Homo sapiens]                                32   2.9  
gi|7662004 mitofusin 2 [Homo sapiens]                                  32   2.9  
gi|23510377 KN motif and ankyrin repeat domains 1 isoform b [Hom...    32   3.8  
gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Hom...    32   3.8  

>gi|197116359 inositol polyphosphate-4-phosphatase, type 1 isoform d
           [Homo sapiens]
          Length = 977

 Score = 1966 bits (5094), Expect = 0.0
 Identities = 977/977 (100%), Positives = 977/977 (100%)

Query: 1   MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60
           MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL
Sbjct: 1   MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60

Query: 61  DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120
           DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY
Sbjct: 61  DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120

Query: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180
           DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR
Sbjct: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180

Query: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240
           PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG
Sbjct: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240

Query: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300
           NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT
Sbjct: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300

Query: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360
           IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI
Sbjct: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360

Query: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT 420
           GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT
Sbjct: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT 420

Query: 421 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 480
           LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD
Sbjct: 421 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 480

Query: 481 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 540
           YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC
Sbjct: 481 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 540

Query: 541 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPST 600
           IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPST
Sbjct: 541 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPST 600

Query: 601 MPSTACHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS 660
           MPSTACHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS
Sbjct: 601 MPSTACHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS 660

Query: 661 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS 720
           APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS
Sbjct: 661 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS 720

Query: 721 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD 780
           TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD
Sbjct: 721 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD 780

Query: 781 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV 840
           ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV
Sbjct: 781 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV 840

Query: 841 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD 900
           LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD
Sbjct: 841 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD 900

Query: 901 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKA 960
           RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKA
Sbjct: 901 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKA 960

Query: 961 FPKHYRPPEGTYGKVET 977
           FPKHYRPPEGTYGKVET
Sbjct: 961 FPKHYRPPEGTYGKVET 977


>gi|197116361 inositol polyphosphate-4-phosphatase, type 1 isoform c
           [Homo sapiens]
          Length = 972

 Score = 1947 bits (5044), Expect = 0.0
 Identities = 972/977 (99%), Positives = 972/977 (99%), Gaps = 5/977 (0%)

Query: 1   MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60
           MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL
Sbjct: 1   MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60

Query: 61  DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120
           DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY
Sbjct: 61  DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120

Query: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180
           DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR
Sbjct: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180

Query: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240
           PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG
Sbjct: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240

Query: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300
           NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT
Sbjct: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300

Query: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360
           IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI
Sbjct: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360

Query: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT 420
           GAPAAHCQGFKSGGLRKKLHKFEETKKH     TSSGCQSIIYIPQDVVRAKEIIAQINT
Sbjct: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKH-----TSSGCQSIIYIPQDVVRAKEIIAQINT 415

Query: 421 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 480
           LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD
Sbjct: 416 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 475

Query: 481 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 540
           YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC
Sbjct: 476 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 535

Query: 541 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPST 600
           IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPST
Sbjct: 536 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPST 595

Query: 601 MPSTACHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS 660
           MPSTACHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS
Sbjct: 596 MPSTACHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS 655

Query: 661 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS 720
           APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS
Sbjct: 656 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS 715

Query: 721 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD 780
           TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD
Sbjct: 716 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD 775

Query: 781 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV 840
           ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV
Sbjct: 776 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV 835

Query: 841 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD 900
           LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD
Sbjct: 836 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD 895

Query: 901 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKA 960
           RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKA
Sbjct: 896 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKA 955

Query: 961 FPKHYRPPEGTYGKVET 977
           FPKHYRPPEGTYGKVET
Sbjct: 956 FPKHYRPPEGTYGKVET 972


>gi|4755140 inositol polyphosphate-4-phosphatase, type 1 isoform a
           [Homo sapiens]
          Length = 938

 Score = 1853 bits (4799), Expect = 0.0
 Identities = 937/977 (95%), Positives = 937/977 (95%), Gaps = 39/977 (3%)

Query: 1   MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60
           MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL
Sbjct: 1   MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60

Query: 61  DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120
           DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY
Sbjct: 61  DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120

Query: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180
           DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR
Sbjct: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180

Query: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240
           PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG
Sbjct: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240

Query: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300
           NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT
Sbjct: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300

Query: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360
           IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI
Sbjct: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360

Query: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT 420
           GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT
Sbjct: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT 420

Query: 421 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 480
           LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD
Sbjct: 421 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 480

Query: 481 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 540
           YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC
Sbjct: 481 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 540

Query: 541 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPST 600
           IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKK                           
Sbjct: 541 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKK--------------------------- 573

Query: 601 MPSTACHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS 660
                        CSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS
Sbjct: 574 ------------DCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS 621

Query: 661 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS 720
           APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS
Sbjct: 622 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS 681

Query: 721 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD 780
           TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD
Sbjct: 682 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD 741

Query: 781 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV 840
           ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV
Sbjct: 742 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV 801

Query: 841 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD 900
           LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD
Sbjct: 802 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD 861

Query: 901 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKA 960
           RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKA
Sbjct: 862 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKA 921

Query: 961 FPKHYRPPEGTYGKVET 977
           FPKHYRPPEGTYGKVET
Sbjct: 922 FPKHYRPPEGTYGKVET 938


>gi|4504705 inositol polyphosphate-4-phosphatase, type 1 isoform b
           [Homo sapiens]
          Length = 954

 Score = 1769 bits (4583), Expect = 0.0
 Identities = 899/946 (95%), Positives = 900/946 (95%), Gaps = 39/946 (4%)

Query: 1   MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60
           MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL
Sbjct: 1   MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60

Query: 61  DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120
           DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY
Sbjct: 61  DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120

Query: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180
           DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR
Sbjct: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180

Query: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240
           PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG
Sbjct: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240

Query: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300
           NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT
Sbjct: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300

Query: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360
           IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI
Sbjct: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360

Query: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT 420
           GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT
Sbjct: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT 420

Query: 421 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 480
           LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD
Sbjct: 421 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 480

Query: 481 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 540
           YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC
Sbjct: 481 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 540

Query: 541 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPST 600
           IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKK                           
Sbjct: 541 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKK--------------------------- 573

Query: 601 MPSTACHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS 660
                        CSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS
Sbjct: 574 ------------DCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS 621

Query: 661 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS 720
           APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS
Sbjct: 622 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS 681

Query: 721 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD 780
           TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD
Sbjct: 682 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD 741

Query: 781 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV 840
           ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV
Sbjct: 742 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV 801

Query: 841 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD 900
           LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD
Sbjct: 802 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD 861

Query: 901 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNV 946
           RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRS G R   T KN+
Sbjct: 862 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSIGTREVVTQKNL 907


>gi|156104897 inositol polyphosphate-4-phosphatase, type II, 105kD
           [Homo sapiens]
          Length = 924

 Score =  734 bits (1894), Expect = 0.0
 Identities = 416/958 (43%), Positives = 584/958 (60%), Gaps = 90/958 (9%)

Query: 41  PDEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSS 100
           P+EP LEF LAC +L  P  DRK N+ V +SV  P +   T+++ TEI+EGT +P+FL+ 
Sbjct: 36  PNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTG 95

Query: 101 IAFFQDSLINQMTQVKLSVYDVKDRSQGTMY-----------------LLGSGTFIVKDL 143
           + F  +  I + T++KL+VYDVKD+S  T+                   LG  +F V +L
Sbjct: 96  VTFPSEYPIYEETKIKLTVYDVKDKSHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGEL 155

Query: 144 LQDRHHRLHLTLRSAESDRV-GNITVIGWQMEEKSDQRPPVTRSVDTVNGRMVLPVDESL 202
           L+ +   L L+LR+++  +V G I V   +M E  D       + D    +  L  + + 
Sbjct: 156 LKSKEQLLVLSLRTSDGGKVVGTIEVSVVKMGEIEDGEADHI-TTDVQGQKCALVCECTA 214

Query: 203 TEALGIRSKYASLRKDTL--LKSVFGGAICRMYRFPTTDGNHLRILEQMAESVLSLHVPR 260
            E++          KD L  L SV    +C++YRFPT+D   +RI EQM+ES+LS H+P+
Sbjct: 215 PESVS--------GKDNLPFLNSVLKNPVCKLYRFPTSDNKWMRIREQMSESILSFHIPK 266

Query: 261 QFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYRGPSF 320
           + + L ++ED  R  E++ELGELSP W++LR+ ++T    ++  YQ+ LT+L +  G SF
Sbjct: 267 ELISLHIKEDLCRNQEIKELGELSPHWDNLRKNVLTHCDQMVNMYQDILTELSKETGSSF 326

Query: 321 KASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTIGAPAAHCQGFKSGGLRKKLH 380
           K+SS K +K LEFVP NLH+QRM+V      D  YD++T+GAPAAH QGFK+GGLRK LH
Sbjct: 327 KSSSSKGEKTLEFVPINLHLQRMQVHSPHLKDALYDVITVGAPAAHFQGFKNGGLRKLLH 386

Query: 381 KFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINTLKTQVSYYAERLSRAAKDRS 440
           +FE  +++       +G Q I Y P++  +AKE+++ IN L+  ++ +A+ L  +A   S
Sbjct: 387 RFETERRN-------TGYQFIYYSPENTAKAKEVLSNINQLQPLIATHADLLLNSASQHS 439

Query: 441 ATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPDYIASKA-SPTSTEEEQVMLR 499
              L+ +L +L++KT   V     +L+ +++  L  ARP  I  K  SP S+ EE     
Sbjct: 440 PDSLKNSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGGILKKPPSPKSSTEESSP-- 497

Query: 500 NDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECIIQRVDKLLQKERLHGEGC 559
            DQ  +M    G++S      D+ EEEW++VW NV KSL CII  VDKL++++       
Sbjct: 498 QDQPPVMR---GQDSIPH-HSDYDEEEWDRVWANVGKSLNCIIAMVDKLIERD------- 546

Query: 560 EDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPSTMPSTACHPHLTTHCSPPPE 619
                  G      GN D                              P LT      P 
Sbjct: 547 -------GGSEGSGGNNDGEK--------------------------EPSLTDAIPSHPR 573

Query: 620 ESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIATYLSLQYRRDVVFC 679
           E    +W E LYPL+ TL DC+  + ++AK+++ F+L+Q+ A ++   L L  RRD+VF 
Sbjct: 574 E----DWYEQLYPLILTLKDCMGEVVNRAKQSLTFVLLQELAYSLPQCLMLTLRRDIVFS 629

Query: 680 QTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDL 739
           Q L  L+CGFIIKL+  L+D GFL+QL+T+GL+ Q+E LLSTY +E+ MLEDM++GI DL
Sbjct: 630 QALAGLVCGFIIKLQTSLYDPGFLQQLHTVGLIVQYEGLLSTYSDEIGMLEDMAVGISDL 689

Query: 740 RNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFDALPREIQSGMLLRVQPVLF 799
           + V FK+ +A S+   D+LPVITG R+ + V V LP  +F++LP +I+ G LL V PVLF
Sbjct: 690 KKVAFKIIEAKSN---DVLPVITGRREHYVVEVKLPARMFESLPLQIKEGQLLHVYPVLF 746

Query: 800 NVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELL 859
           NVGINEQQTLAERFGD SLQE IN E+   L  Y++ F E +P D +   + Q  L  LL
Sbjct: 747 NVGINEQQTLAERFGDVSLQESINQENFELLQEYYKIFMEKMPPDYISHFQEQNDLKALL 806

Query: 860 RFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHG 919
             L QN+ ++K KNV+I+W AA ICR+LNG+RFT CKSAKDRT+MSVTLEQC IL+ EH 
Sbjct: 807 ENLLQNIQSKKRKNVEIMWLAATICRKLNGIRFTCCKSAKDRTSMSVTLEQCSILRDEHQ 866

Query: 920 MAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKAFPKHYRPPEGTYGKVET 977
           +    F +AL+CMR EGCR EN +KN+  RKYAFN LQL AFPK+YRPPEGTYGK +T
Sbjct: 867 LHKDFFIRALDCMRREGCRIENVLKNIKCRKYAFNMLQLMAFPKYYRPPEGTYGKADT 924


>gi|156104895 inositol polyphosphate-4-phosphatase, type II, 105kD
           [Homo sapiens]
          Length = 924

 Score =  734 bits (1894), Expect = 0.0
 Identities = 416/958 (43%), Positives = 584/958 (60%), Gaps = 90/958 (9%)

Query: 41  PDEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSS 100
           P+EP LEF LAC +L  P  DRK N+ V +SV  P +   T+++ TEI+EGT +P+FL+ 
Sbjct: 36  PNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTG 95

Query: 101 IAFFQDSLINQMTQVKLSVYDVKDRSQGTMY-----------------LLGSGTFIVKDL 143
           + F  +  I + T++KL+VYDVKD+S  T+                   LG  +F V +L
Sbjct: 96  VTFPSEYPIYEETKIKLTVYDVKDKSHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGEL 155

Query: 144 LQDRHHRLHLTLRSAESDRV-GNITVIGWQMEEKSDQRPPVTRSVDTVNGRMVLPVDESL 202
           L+ +   L L+LR+++  +V G I V   +M E  D       + D    +  L  + + 
Sbjct: 156 LKSKEQLLVLSLRTSDGGKVVGTIEVSVVKMGEIEDGEADHI-TTDVQGQKCALVCECTA 214

Query: 203 TEALGIRSKYASLRKDTL--LKSVFGGAICRMYRFPTTDGNHLRILEQMAESVLSLHVPR 260
            E++          KD L  L SV    +C++YRFPT+D   +RI EQM+ES+LS H+P+
Sbjct: 215 PESVS--------GKDNLPFLNSVLKNPVCKLYRFPTSDNKWMRIREQMSESILSFHIPK 266

Query: 261 QFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYRGPSF 320
           + + L ++ED  R  E++ELGELSP W++LR+ ++T    ++  YQ+ LT+L +  G SF
Sbjct: 267 ELISLHIKEDLCRNQEIKELGELSPHWDNLRKNVLTHCDQMVNMYQDILTELSKETGSSF 326

Query: 321 KASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTIGAPAAHCQGFKSGGLRKKLH 380
           K+SS K +K LEFVP NLH+QRM+V      D  YD++T+GAPAAH QGFK+GGLRK LH
Sbjct: 327 KSSSSKGEKTLEFVPINLHLQRMQVHSPHLKDALYDVITVGAPAAHFQGFKNGGLRKLLH 386

Query: 381 KFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINTLKTQVSYYAERLSRAAKDRS 440
           +FE  +++       +G Q I Y P++  +AKE+++ IN L+  ++ +A+ L  +A   S
Sbjct: 387 RFETERRN-------TGYQFIYYSPENTAKAKEVLSNINQLQPLIATHADLLLNSASQHS 439

Query: 441 ATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPDYIASKA-SPTSTEEEQVMLR 499
              L+ +L +L++KT   V     +L+ +++  L  ARP  I  K  SP S+ EE     
Sbjct: 440 PDSLKNSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGGILKKPPSPKSSTEESSP-- 497

Query: 500 NDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECIIQRVDKLLQKERLHGEGC 559
            DQ  +M    G++S      D+ EEEW++VW NV KSL CII  VDKL++++       
Sbjct: 498 QDQPPVMR---GQDSIPH-HSDYDEEEWDRVWANVGKSLNCIIAMVDKLIERD------- 546

Query: 560 EDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPSTMPSTACHPHLTTHCSPPPE 619
                  G      GN D                              P LT      P 
Sbjct: 547 -------GGSEGSGGNNDGEK--------------------------EPSLTDAIPSHPR 573

Query: 620 ESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIATYLSLQYRRDVVFC 679
           E    +W E LYPL+ TL DC+  + ++AK+++ F+L+Q+ A ++   L L  RRD+VF 
Sbjct: 574 E----DWYEQLYPLILTLKDCMGEVVNRAKQSLTFVLLQELAYSLPQCLMLTLRRDIVFS 629

Query: 680 QTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDL 739
           Q L  L+CGFIIKL+  L+D GFL+QL+T+GL+ Q+E LLSTY +E+ MLEDM++GI DL
Sbjct: 630 QALAGLVCGFIIKLQTSLYDPGFLQQLHTVGLIVQYEGLLSTYSDEIGMLEDMAVGISDL 689

Query: 740 RNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFDALPREIQSGMLLRVQPVLF 799
           + V FK+ +A S+   D+LPVITG R+ + V V LP  +F++LP +I+ G LL V PVLF
Sbjct: 690 KKVAFKIIEAKSN---DVLPVITGRREHYVVEVKLPARMFESLPLQIKEGQLLHVYPVLF 746

Query: 800 NVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELL 859
           NVGINEQQTLAERFGD SLQE IN E+   L  Y++ F E +P D +   + Q  L  LL
Sbjct: 747 NVGINEQQTLAERFGDVSLQESINQENFELLQEYYKIFMEKMPPDYISHFQEQNDLKALL 806

Query: 860 RFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHG 919
             L QN+ ++K KNV+I+W AA ICR+LNG+RFT CKSAKDRT+MSVTLEQC IL+ EH 
Sbjct: 807 ENLLQNIQSKKRKNVEIMWLAATICRKLNGIRFTCCKSAKDRTSMSVTLEQCSILRDEHQ 866

Query: 920 MAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKAFPKHYRPPEGTYGKVET 977
           +    F +AL+CMR EGCR EN +KN+  RKYAFN LQL AFPK+YRPPEGTYGK +T
Sbjct: 867 LHKDFFIRALDCMRREGCRIENVLKNIKCRKYAFNMLQLMAFPKYYRPPEGTYGKADT 924


>gi|47578115 DEP domain containing 2 isoform a [Homo sapiens]
          Length = 1606

 Score =  123 bits (308), Expect = 1e-27
 Identities = 106/394 (26%), Positives = 171/394 (43%), Gaps = 62/394 (15%)

Query: 602  PSTACHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDSA 661
            P  +C   L  H    P       W+  L   + TL   +    ++ K  ++  L++ S 
Sbjct: 1206 PKLSCPKRLRLHIKQDP-------WN--LPSSVRTLAQNIRKFVEEVKCRLLLALLEYSD 1256

Query: 662  PTIATYLSLQYRRDVVFCQTLTALICGFIIKLR---NCLHDDG-------------FLRQ 705
                     Q RRD+VFCQTL A +C F  +L    N + D+              +L Q
Sbjct: 1257 S------ETQLRRDMVFCQTLVATVCAFSEQLMAALNQMFDNSKENEMETWEASRRWLDQ 1310

Query: 706  LYTIGLLAQFESLLS-TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVI--- 761
            +   G+L  F+SLLS    +E AMLED  + + DL  V+F    +        +P+    
Sbjct: 1311 IANAGVLFHFQSLLSPNLTDEQAMLEDTLVALFDLEKVSFYFKPSEEEPLVANVPLTYQA 1370

Query: 762  TGNRDGFNVRVPLPGPLFDALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEV 821
             G+R    V   +    F+ LP+ +++G   ++ PVLF   +   +    R  + S++E 
Sbjct: 1371 EGSRQALKVYFYIDSYHFEQLPQRLKNGGGFKIHPVLFAQALESMEGYYYR-DNVSVEEF 1429

Query: 822  ---INVESLVRLNSYFEQFKEVLPE--DCLPRSRSQTC-----------LPELLRFLGQN 865
               IN  SL ++  Y ++ +    +  +  P S S+             L EL R +   
Sbjct: 1430 QAQINAASLEKVKQYNQKLRAFYLDKSNSPPNSTSKAAYVDKLMRPLNALDELYRLVASF 1489

Query: 866  VHARKN----------KNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQ 915
            + +++             V +L  ++E+C RL       C S   R  +SVTLEQ +IL 
Sbjct: 1490 IRSKRTAACANTACSASGVGLLSVSSELCNRLGACHIIMCSSGVHRCTLSVTLEQAIILA 1549

Query: 916  HEHGMAPQVFTQALECMRSEGCRRENTMKNVGSR 949
              HG+ P+   QA + MR +G R +NT KN+G R
Sbjct: 1550 RSHGLPPRYIMQATDVMRKQGARVQNTAKNLGVR 1583



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 40/182 (21%), Positives = 76/182 (41%), Gaps = 16/182 (8%)

Query: 175 EKSDQRPPVTRSVDTVNGRMVLPVDESLTEAL-GIRSKYASLRKDTLLKSVFGGAICRMY 233
           +KS  +PP   + D  + ++   +D+  T A+   + ++ SL  D +      G +   Y
Sbjct: 769 QKSHSKPPGDEAGDAFDCKVEEVIDKFNTMAIIDGKKEHVSLTVDNVHLEY--GVV---Y 823

Query: 234 RFPTTDGNHLRILEQMAESVLSLHVPRQFVKLLLEEDAARV---CELEELGELSPC---- 286
            + +T G    ++E+M E      +  + ++ L + D   V     L  L E+ P     
Sbjct: 824 EYDSTAGIKCNVVEKMIEPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNEVIPTDLQS 883

Query: 287 -WESLRRQIVTQYQTIILTYQENLTDLHQYRGPSFKASSLKADK--KLEFVPTNLHIQRM 343
            + +L  + +      I +Y++    L     P+FK +  K       +F PTN H+  M
Sbjct: 884 KFSALCSERIEHLCQRISSYKKFSRVLKNRAWPTFKQAKSKISPLHSSDFCPTNCHVNVM 943

Query: 344 RV 345
            V
Sbjct: 944 EV 945


>gi|34452732 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac
            exchange factor 1 [Homo sapiens]
          Length = 1659

 Score =  120 bits (300), Expect = 8e-27
 Identities = 101/352 (28%), Positives = 157/352 (44%), Gaps = 45/352 (12%)

Query: 634  LTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIATYLSLQYRRDVVFCQTLTALICGFIIKL 693
            + TL D +    +  K  ++  L++       T   LQ RRD +FCQ L A +C F  +L
Sbjct: 1289 IKTLVDNIQRYVEDGKNQLLLALLK------CTDTELQLRRDAIFCQALVAAVCTFSEQL 1342

Query: 694  RNCL----HDDG------------FLRQLYTIGLLAQFESLLS--TYGEELAMLEDMSLG 735
               L    +++G            +L Q+   G+L   +SLLS  T  EE  MLED+ + 
Sbjct: 1343 LAALGYRYNNNGEYEESSRDASRKWLEQVAATGVLLHCQSLLSPATVKEERTMLEDIWVT 1402

Query: 736  IMDLRNVTFKVTQATSS--ASADMLPVITGNRDGFNVRVPLPGPLFDALPREIQSGMLLR 793
            + +L NVTF   Q   +  A+ ++   I G+R    V   L    F  LP  ++ G  LR
Sbjct: 1403 LSELDNVTFSFKQLDENYVANTNVFYHIEGSRQALKVIFYLDSYHFSKLPSRLEGGASLR 1462

Query: 794  VQPVLFNVGINEQQTLAERFGDTS--LQEVINVESLVRLNSYFEQFKEV-LPEDCLPRSR 850
            +   LF   +   + L       +  LQ+ IN +SL ++  Y+ + +   L    LP   
Sbjct: 1463 LHTALFTKVLENVEGLPSPGSQAAEDLQQDINAQSLEKVQQYYRKLRAFYLERSNLPTDA 1522

Query: 851  SQTC------------LPELLRFLGQNVH----ARKNKNVDILWQAAEICRRLNGVRFTS 894
            S T             L EL R +   VH    A  +    ++  ++E+C RL   +   
Sbjct: 1523 STTAVKIDQLIRPINALDELCRLMKSFVHPKPGAAGSVGAGLIPISSELCYRLGACQMVM 1582

Query: 895  CKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNV 946
            C +   R+ +SV+LEQ  IL   HG+ P+   QA + MR +G R E   KN+
Sbjct: 1583 CGTGMQRSTLSVSLEQAAILARSHGLLPKCIMQATDIMRKQGPRVEILAKNL 1634



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 32/124 (25%), Positives = 51/124 (41%), Gaps = 10/124 (8%)

Query: 232 MYRFPTTDGNHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESL- 290
           +Y + +T G    +LE++ E      +  + ++     D+  V     L  LS    ++ 
Sbjct: 856 VYEYVSTAGVRCHVLEKIVEPRGCFGLTAKILEAFAANDSVFVENCRRLMALSSAIVTMP 915

Query: 291 ----RRQIVTQYQTI---ILTYQENLTDLHQYRGPSFKASSLKADKK--LEFVPTNLHIQ 341
               R    T+ ++I   I  YQE    L     P FK + L+      L+F PTN HI 
Sbjct: 916 HFEFRNICDTKLESIGQRIACYQEFAAQLKSRVSPPFKQAPLEPHPLCGLDFCPTNCHIN 975

Query: 342 RMRV 345
            M V
Sbjct: 976 LMEV 979


>gi|88703066 copine-like protein [Homo sapiens]
          Length = 553

 Score = 36.2 bits (82), Expect = 0.15
 Identities = 27/135 (20%), Positives = 53/135 (39%), Gaps = 4/135 (2%)

Query: 46  LEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQ 105
           +E +++C  L       K +  V +   +     W +  +TE+I+ T NP F+    F  
Sbjct: 16  IEITVSCRNLLDLDTFSKSDPMVVLYTQSRASQEWREFGRTEVIDNTLNPDFVRK--FVL 73

Query: 106 DSLINQMTQVKLSVYDV--KDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRV 163
           D    +   ++  VY+V  K         LG     + +++  +  R+  TL      + 
Sbjct: 74  DYFFEEKQNLRFDVYNVDSKTNISKPKDFLGQAFLALGEVIGGQGSRVERTLTGVPGKKC 133

Query: 164 GNITVIGWQMEEKSD 178
           G I +   ++    D
Sbjct: 134 GTILLTAEELSNCRD 148


>gi|25141328 copine 7 isoform a [Homo sapiens]
          Length = 558

 Score = 35.4 bits (80), Expect = 0.26
 Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 8/88 (9%)

Query: 36  GNIQDPDEPILEFSLACSELHTPSLDRKP--NSFVAVSVTTPPQAFWTKHAQTEIIEGTN 93
           G +  P    +E  L+C  L    LDR P   S  +V++    Q  W +  +TE++  + 
Sbjct: 14  GGLPAPCASKVELRLSCRHL----LDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSL 69

Query: 94  NPIFLSSIAFFQDSLINQMTQVKLSVYD 121
           +P+F  S  F  D    ++ +++  VYD
Sbjct: 70  HPVF--SKVFTVDYYFEEVQRLRFEVYD 95


>gi|7656993 copine 7 isoform b [Homo sapiens]
          Length = 633

 Score = 35.4 bits (80), Expect = 0.26
 Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 8/88 (9%)

Query: 36  GNIQDPDEPILEFSLACSELHTPSLDRKP--NSFVAVSVTTPPQAFWTKHAQTEIIEGTN 93
           G +  P    +E  L+C  L    LDR P   S  +V++    Q  W +  +TE++  + 
Sbjct: 14  GGLPAPCASKVELRLSCRHL----LDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSL 69

Query: 94  NPIFLSSIAFFQDSLINQMTQVKLSVYD 121
           +P+F  S  F  D    ++ +++  VYD
Sbjct: 70  HPVF--SKVFTVDYYFEEVQRLRFEVYD 95


>gi|25141323 copine V [Homo sapiens]
          Length = 593

 Score = 35.0 bits (79), Expect = 0.34
 Identities = 23/94 (24%), Positives = 41/94 (43%), Gaps = 5/94 (5%)

Query: 33  SLAGNIQDPDEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGT 92
           SLAG+I       +E +++C  L    +  K +    +         W +  +TE+I+ T
Sbjct: 15  SLAGSIPATK---VEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNT 71

Query: 93  NNPIFLSSIAFFQDSLINQMTQVKLSVYDVKDRS 126
            NP F+    F  D    +   ++  +YDV  +S
Sbjct: 72  LNPDFVRK--FIVDYFFEEKQNLRFDLYDVDSKS 103


>gi|45269137 mitofusin 1 [Homo sapiens]
          Length = 741

 Score = 34.3 bits (77), Expect = 0.59
 Identities = 17/57 (29%), Positives = 31/57 (54%), Gaps = 2/57 (3%)

Query: 374 GLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINTLKTQVSYYAE 430
           G   +L +F+  ++ FEEC + S  ++     Q  +RAK+I+A +  +   V+  AE
Sbjct: 309 GFHARLQEFQNFEQIFEECISQSAVKT--KFEQHTIRAKQILATVKNIMDSVNLAAE 363


>gi|226498192 atonal homolog 8 [Homo sapiens]
          Length = 321

 Score = 33.9 bits (76), Expect = 0.76
 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 5/63 (7%)

Query: 574 GNPDSHAY---WIRPEDPFCDVPSSPCPSTMPSTACHPHLTTHCSPP--PEESSPGEWSE 628
           G P++  +    +RP    C  P+ P PS  P+    P  T   +PP  P ESS    S 
Sbjct: 138 GGPEAQPFREPGLRPRILLCAPPARPAPSAPPAPPAPPESTVRPAPPTRPGESSYSSISH 197

Query: 629 ALY 631
            +Y
Sbjct: 198 VIY 200


>gi|126090909 engrailed homeobox 1 [Homo sapiens]
          Length = 392

 Score = 33.9 bits (76), Expect = 0.76
 Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 3/54 (5%)

Query: 567 GSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPSTMPSTACHPHLTTHCSPPPEE 620
           G+  S     D  +  + P+      P++PC   +P  A HPHL  H  PPP +
Sbjct: 34  GASGSSGSGSDGDSVPVSPQPAPPSPPAAPC---LPPLAHHPHLPPHPPPPPPQ 84


>gi|25121972 copine VIII [Homo sapiens]
          Length = 564

 Score = 33.9 bits (76), Expect = 0.76
 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 2/81 (2%)

Query: 46  LEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQ 105
           +E S++C  L       K +    + V       W +  +TE+I+ T NP F+    F  
Sbjct: 26  VEVSVSCRNLLDRDTFSKSDPICVLYVQGVGNKEWREFGRTEVIDNTLNPDFVRK--FIL 83

Query: 106 DSLINQMTQVKLSVYDVKDRS 126
           D    +   ++  +YDV  +S
Sbjct: 84  DYFFEERENLRFDLYDVDSKS 104


>gi|169201827 PREDICTED: similar to hCG1798126 [Homo sapiens]
          Length = 269

 Score = 33.5 bits (75), Expect = 1.00
 Identities = 25/57 (43%), Positives = 27/57 (47%), Gaps = 8/57 (14%)

Query: 588 PF-CDVPSS-PCPSTMPSTACHPHLTT--HCSPPPEESSPGEWSEALYPLLTTLTDC 640
           PF C +P   P P T PS A +P L T  HC P P  S     S A YP L T   C
Sbjct: 113 PFLCTLPHCFPLPGTSPSCARYPFLCTSPHCFPLPATSP----SCARYPFLCTSPHC 165



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 21/47 (44%), Positives = 23/47 (48%), Gaps = 6/47 (12%)

Query: 596 PCPSTMPSTACHPHLTT--HCSPPPEESSPGEWSEALYPLLTTLTDC 640
           P P+T PS A +P L T  HC P P  S     S A YP L T   C
Sbjct: 145 PLPATSPSCARYPFLCTSPHCFPLPATSP----SCARYPFLCTSPHC 187



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 21/44 (47%), Positives = 22/44 (50%), Gaps = 6/44 (13%)

Query: 596 PCPSTMPSTACHPHLTT--HCSPPPEESSPGEWSEALYPLLTTL 637
           P P T PS A +P L T  HC P P  S     S A YP L TL
Sbjct: 189 PLPGTSPSCARYPFLCTSPHCFPLPGTSP----SCARYPFLCTL 228


>gi|169201475 PREDICTED: similar to hCG1798126, partial [Homo
           sapiens]
          Length = 190

 Score = 33.5 bits (75), Expect = 1.00
 Identities = 25/57 (43%), Positives = 27/57 (47%), Gaps = 8/57 (14%)

Query: 588 PF-CDVPSS-PCPSTMPSTACHPHLTT--HCSPPPEESSPGEWSEALYPLLTTLTDC 640
           PF C +P   P P T PS A +P L T  HC P P  S     S A YP L T   C
Sbjct: 34  PFLCTLPHCFPLPGTSPSCARYPFLCTSPHCFPLPATSP----SCARYPFLCTSPHC 86



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 21/47 (44%), Positives = 23/47 (48%), Gaps = 6/47 (12%)

Query: 596 PCPSTMPSTACHPHLTT--HCSPPPEESSPGEWSEALYPLLTTLTDC 640
           P P+T PS A +P L T  HC P P  S     S A YP L T   C
Sbjct: 66  PLPATSPSCARYPFLCTSPHCFPLPATSP----SCARYPFLCTSPHC 108



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 21/44 (47%), Positives = 22/44 (50%), Gaps = 6/44 (13%)

Query: 596 PCPSTMPSTACHPHLTT--HCSPPPEESSPGEWSEALYPLLTTL 637
           P P T PS A +P L T  HC P P  S     S A YP L TL
Sbjct: 110 PLPGTSPSCARYPFLCTSPHCFPLPGTSP----SCARYPFLCTL 149


>gi|169190743 PREDICTED: similar to hCG1798126 [Homo sapiens]
          Length = 269

 Score = 33.5 bits (75), Expect = 1.00
 Identities = 25/57 (43%), Positives = 27/57 (47%), Gaps = 8/57 (14%)

Query: 588 PF-CDVPSS-PCPSTMPSTACHPHLTT--HCSPPPEESSPGEWSEALYPLLTTLTDC 640
           PF C +P   P P T PS A +P L T  HC P P  S     S A YP L T   C
Sbjct: 113 PFLCTLPHCFPLPGTSPSCARYPFLCTSPHCFPLPATSP----SCARYPFLCTSPHC 165



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 21/47 (44%), Positives = 23/47 (48%), Gaps = 6/47 (12%)

Query: 596 PCPSTMPSTACHPHLTT--HCSPPPEESSPGEWSEALYPLLTTLTDC 640
           P P+T PS A +P L T  HC P P  S     S A YP L T   C
Sbjct: 145 PLPATSPSCARYPFLCTSPHCFPLPATSP----SCARYPFLCTSPHC 187



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 21/44 (47%), Positives = 22/44 (50%), Gaps = 6/44 (13%)

Query: 596 PCPSTMPSTACHPHLTT--HCSPPPEESSPGEWSEALYPLLTTL 637
           P P T PS A +P L T  HC P P  S     S A YP L TL
Sbjct: 189 PLPGTSPSCARYPFLCTSPHCFPLPGTSP----SCARYPFLCTL 228


>gi|29789058 WW and C2 domain containing 1 isoform 3 [Homo sapiens]
          Length = 1113

 Score = 33.1 bits (74), Expect = 1.3
 Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 19/100 (19%)

Query: 482 IASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECI 541
           +A  + P ST+    +L      L  R  GR+S  +L+  W  EE            E +
Sbjct: 802 MAPASGPASTDAVSALLEQTAVELEKRQEGRSSTQTLEDSWRYEE--------TSENEAV 853

Query: 542 IQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAY 581
            +  ++ +++E    EG EDVF       ++K +PD   Y
Sbjct: 854 AEEEEEEVEEE----EGEEDVF-------TEKASPDMDGY 882


>gi|242247257 WW and C2 domain containing 1 isoform 2 [Homo sapiens]
          Length = 1118

 Score = 33.1 bits (74), Expect = 1.3
 Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 19/100 (19%)

Query: 482 IASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECI 541
           +A  + P ST+    +L      L  R  GR+S  +L+  W  EE            E +
Sbjct: 802 MAPASGPASTDAVSALLEQTAVELEKRQEGRSSTQTLEDSWRYEE--------TSENEAV 853

Query: 542 IQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAY 581
            +  ++ +++E    EG EDVF       ++K +PD   Y
Sbjct: 854 AEEEEEEVEEE----EGEEDVF-------TEKASPDMDGY 882


>gi|242247251 WW and C2 domain containing 1 isoform 1 [Homo sapiens]
          Length = 1119

 Score = 33.1 bits (74), Expect = 1.3
 Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 19/100 (19%)

Query: 482 IASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECI 541
           +A  + P ST+    +L      L  R  GR+S  +L+  W  EE            E +
Sbjct: 802 MAPASGPASTDAVSALLEQTAVELEKRQEGRSSTQTLEDSWRYEE--------TSENEAV 853

Query: 542 IQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAY 581
            +  ++ +++E    EG EDVF       ++K +PD   Y
Sbjct: 854 AEEEEEEVEEE----EGEEDVF-------TEKASPDMDGY 882


>gi|126116565 MYC binding protein 2 [Homo sapiens]
          Length = 4640

 Score = 33.1 bits (74), Expect = 1.3
 Identities = 38/137 (27%), Positives = 63/137 (45%), Gaps = 24/137 (17%)

Query: 201  SLTEALGIRSKYASLRKDTLLKSVFGGAICRM-YRFPTTDGNHLRILEQMAESVLSLHVP 259
            S+T   G+  ++ S +K      V  G I ++ YR PT+DG+  +  +Q +E V   H+ 
Sbjct: 1313 SITTDDGVVFQFKSSKKSNNGTDVNAGQIPQLLYRLPTSDGSASKGKQQTSEPV---HI- 1368

Query: 260  RQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYRGPS 319
                   L+   AR   +E       C+ESL   +   + T++L  +E    L   +G  
Sbjct: 1369 -------LKRSFARTVSVE-------CFESLLSILHWSWTTLVLGVEE----LRGLKGFQ 1410

Query: 320  FKASSLKADKKLEFVPT 336
            F A+ L  + +L FV T
Sbjct: 1411 FTATLLDLE-RLRFVGT 1426


>gi|34304360 nephrocystin 3 [Homo sapiens]
          Length = 1330

 Score = 32.7 bits (73), Expect = 1.7
 Identities = 26/116 (22%), Positives = 53/116 (45%), Gaps = 13/116 (11%)

Query: 260 RQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYRGPS 319
           + + K+L E+++A   + + + E +  +E  R ++  Q++    T +  + DL       
Sbjct: 135 KTYQKILREKESALEAKYQAM-ERAATFEHDRDKVKRQFKIFRETKENEIQDL------- 186

Query: 320 FKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTIGAPAAHCQGFKSGGL 375
                L+A ++LE     L  Q ++V D G SD + +   + A    C+ +  G L
Sbjct: 187 -----LRAKRELESKLQRLQAQGIQVFDPGESDSDDNCTDVTAAGTQCEYWTGGAL 237


>gi|116268109 nucleotide-binding oligomerization domains 27 [Homo
           sapiens]
          Length = 1866

 Score = 32.7 bits (73), Expect = 1.7
 Identities = 29/111 (26%), Positives = 55/111 (49%), Gaps = 11/111 (9%)

Query: 249 MAESVLSLHVPRQFVKLLLEEDAARVCELE-ELGELSPCWESLRRQIVTQYQTIILTYQE 307
           MAE+   LH+ R   KL L ++   V  +   L  +S CW      I  Q++T+I  + +
Sbjct: 890 MAEAASQLHIAR---KLDLSDNGLSVAGVHCVLRAVSACWTLAELHISLQHKTVIFMFAQ 946

Query: 308 NLTDLHQYRGPSFKASSLKADKKLEFVPTNLHI--QRMRVQDDGGSDQNYD 356
              +  + +GP  +A+ L  D  +  +P+ L +  +RMR+   G  +++ +
Sbjct: 947 ---EPEEQKGPQERAAFL--DSLMLQMPSELPLSSRRMRLTHCGLQEKHLE 992


>gi|28875784 armadillo repeat containing 5 isoform b [Homo sapiens]
          Length = 725

 Score = 32.3 bits (72), Expect = 2.2
 Identities = 20/42 (47%), Positives = 22/42 (52%), Gaps = 8/42 (19%)

Query: 588 PFCDVPSSPCPSTMPSTACHPHLTTHCSP---PPEESSPGEW 626
           P C+ PSSP  S  P     PHL TH S    PP+  SP EW
Sbjct: 632 PPCESPSSPMASMGP----EPHLPTHLSSPARPPDNLSP-EW 668


>gi|189083768 mitofusin 2 [Homo sapiens]
          Length = 757

 Score = 32.0 bits (71), Expect = 2.9
 Identities = 36/165 (21%), Positives = 64/165 (38%), Gaps = 38/165 (23%)

Query: 305 YQENLTDLHQYRGPSFKASSL------KADKKLEFVPT----NLHIQRMRVQDDGGSDQN 354
           Y E +   H  R  SF    L      +A  ++ FV      N  IQ+ +   +GG    
Sbjct: 269 YMEEVRRQHMERCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQGMPEGG---- 324

Query: 355 YDIVTIGAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEI 414
                         G  + G + ++ +F+  ++ FEEC + S  ++     Q  VRAK+I
Sbjct: 325 --------------GALAEGFQVRMFEFQNFERRFEECISQSAVKT--KFEQHTVRAKQI 368

Query: 415 IAQINTLKTQV-------SYYAERLSRAAKDRSATGLERTLAILA 452
              +  +   +         Y E +    +DR    +++ L +LA
Sbjct: 369 AEAVRLIMDSLHMAAREQQVYCEEMREERQDR-LKFIDKQLELLA 412


>gi|7662004 mitofusin 2 [Homo sapiens]
          Length = 757

 Score = 32.0 bits (71), Expect = 2.9
 Identities = 36/165 (21%), Positives = 64/165 (38%), Gaps = 38/165 (23%)

Query: 305 YQENLTDLHQYRGPSFKASSL------KADKKLEFVPT----NLHIQRMRVQDDGGSDQN 354
           Y E +   H  R  SF    L      +A  ++ FV      N  IQ+ +   +GG    
Sbjct: 269 YMEEVRRQHMERCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQGMPEGG---- 324

Query: 355 YDIVTIGAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEI 414
                         G  + G + ++ +F+  ++ FEEC + S  ++     Q  VRAK+I
Sbjct: 325 --------------GALAEGFQVRMFEFQNFERRFEECISQSAVKT--KFEQHTVRAKQI 368

Query: 415 IAQINTLKTQV-------SYYAERLSRAAKDRSATGLERTLAILA 452
              +  +   +         Y E +    +DR    +++ L +LA
Sbjct: 369 AEAVRLIMDSLHMAAREQQVYCEEMREERQDR-LKFIDKQLELLA 412


>gi|23510377 KN motif and ankyrin repeat domains 1 isoform b [Homo
           sapiens]
          Length = 1194

 Score = 31.6 bits (70), Expect = 3.8
 Identities = 31/141 (21%), Positives = 59/141 (41%), Gaps = 17/141 (12%)

Query: 421 LKTQVSYYAERLSRAAKD-RSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARP 479
           ++ Q++   +RL    +  R+   L+  +++L ++ RQLV+    +  A+ I+     + 
Sbjct: 105 IREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQLVSQLKNQRAASQINVCGVRKR 164

Query: 480 DYIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLE 539
            Y A  AS    + EQ+               R S   L +D+ EEE E V  +  +  E
Sbjct: 165 SYSAGNAS----QLEQLS------------RARRSGGELYIDYEEEEMETVEQSTQRIKE 208

Query: 540 CIIQRVDKLLQKERLHGEGCE 560
                 D    ++++    CE
Sbjct: 209 FRQLTADMQALEQKIQDSSCE 229


>gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Homo
           sapiens]
          Length = 1352

 Score = 31.6 bits (70), Expect = 3.8
 Identities = 31/141 (21%), Positives = 59/141 (41%), Gaps = 17/141 (12%)

Query: 421 LKTQVSYYAERLSRAAKD-RSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARP 479
           ++ Q++   +RL    +  R+   L+  +++L ++ RQLV+    +  A+ I+     + 
Sbjct: 263 IREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQLVSQLKNQRAASQINVCGVRKR 322

Query: 480 DYIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLE 539
            Y A  AS    + EQ+               R S   L +D+ EEE E V  +  +  E
Sbjct: 323 SYSAGNAS----QLEQLS------------RARRSGGELYIDYEEEEMETVEQSTQRIKE 366

Query: 540 CIIQRVDKLLQKERLHGEGCE 560
                 D    ++++    CE
Sbjct: 367 FRQLTADMQALEQKIQDSSCE 387


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,002,833
Number of Sequences: 37866
Number of extensions: 1689172
Number of successful extensions: 5171
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 5120
Number of HSP's gapped (non-prelim): 58
length of query: 977
length of database: 18,247,518
effective HSP length: 112
effective length of query: 865
effective length of database: 14,006,526
effective search space: 12115644990
effective search space used: 12115644990
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.