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Search of human proteins with 197085610
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
(397 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] 803 0.0
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] 717 0.0
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] 209 5e-54
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] 209 5e-54
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] 209 5e-54
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] 209 5e-54
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] 209 5e-54
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens] 209 5e-54
gi|4503383 dopamine receptor D1 [Homo sapiens] 207 1e-53
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] 205 7e-53
gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens] 204 1e-52
gi|4557265 beta-1-adrenergic receptor [Homo sapiens] 202 3e-52
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 201 1e-51
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] 201 1e-51
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] 201 1e-51
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] 201 1e-51
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] 201 1e-51
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] 199 5e-51
gi|4503391 dopamine receptor D5 [Homo sapiens] 197 1e-50
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens] 192 3e-49
gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] 184 2e-46
gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] 184 2e-46
gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] 184 2e-46
gi|21264324 trace amine associated receptor 1 [Homo sapiens] 180 2e-45
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi... 178 9e-45
gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo sa... 176 3e-44
gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo sap... 175 6e-44
gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap... 160 1e-39
gi|4504537 5-hydroxytryptamine (serotonin) receptor 1E [Homo sap... 157 2e-38
gi|223633986 trace amine associated receptor 5 [Homo sapiens] 155 5e-38
>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
Length = 397
Score = 803 bits (2075), Expect = 0.0
Identities = 397/397 (100%), Positives = 397/397 (100%)
Query: 1 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSL 60
MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSL
Sbjct: 1 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSL 60
Query: 61 AITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV 120
AITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
Sbjct: 61 AITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV 120
Query: 121 MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNE 180
MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNE
Sbjct: 121 MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNE 180
Query: 181 VYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVM 240
VYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVM
Sbjct: 181 VYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVM 240
Query: 241 GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQ 300
GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQ
Sbjct: 241 GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQ 300
Query: 301 QLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDRP 360
QLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDRP
Sbjct: 301 QLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDRP 360
Query: 361 WLCLPECWSVELTHSFIHLFIHSFANIHPIPTTCQEL 397
WLCLPECWSVELTHSFIHLFIHSFANIHPIPTTCQEL
Sbjct: 361 WLCLPECWSVELTHSFIHLFIHSFANIHPIPTTCQEL 397
>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
Length = 359
Score = 717 bits (1851), Expect = 0.0
Identities = 359/359 (100%), Positives = 359/359 (100%)
Query: 1 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSL 60
MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSL
Sbjct: 1 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSL 60
Query: 61 AITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV 120
AITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
Sbjct: 61 AITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV 120
Query: 121 MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNE 180
MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNE
Sbjct: 121 MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNE 180
Query: 181 VYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVM 240
VYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVM
Sbjct: 181 VYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVM 240
Query: 241 GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQ 300
GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQ
Sbjct: 241 GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQ 300
Query: 301 QLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR 359
QLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR
Sbjct: 301 QLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR 359
>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
Length = 359
Score = 209 bits (531), Expect = 5e-54
Identities = 124/312 (39%), Positives = 176/312 (56%), Gaps = 25/312 (8%)
Query: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVSLAITDLLLGLLVLPFSA 76
K+ + L+ +IL+ + GN++V +AV +R+LR + TN FIVSLA DLL+ +LV+PF A
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 77 IYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV-MDPLRYPVLVTPVRV 135
I + W +G+VFC + TSLDV+L TASI +L ISLDRY A+ PL Y +TP+R+
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 136 AISLVLIWVISITLSFLSIHLGWNS-------RNETSKGNHTTSKCKVQVNEVYGLVDGL 188
A+ L WVI +SFL I GWN+ N ++ C VN+ Y + +
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198
Query: 189 VTFYLPLLIMCITYYRIFKVARDQAKRINHI------------SSWKAATIR---EHKAT 233
V FY+P L+M + YYRI+ A++ A +I + S+ + +T R E KA
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAA 258
Query: 234 VTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNR 293
TL +MG F +CW P+F + +V A LWLGY NS LNP LYA LN+
Sbjct: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYINSGLNPFLYAFLNK 317
Query: 294 DFRTGYQQLFCC 305
FR + + CC
Sbjct: 318 SFRRAFLIILCC 329
>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
Length = 428
Score = 209 bits (531), Expect = 5e-54
Identities = 124/312 (39%), Positives = 176/312 (56%), Gaps = 25/312 (8%)
Query: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVSLAITDLLLGLLVLPFSA 76
K+ + L+ +IL+ + GN++V +AV +R+LR + TN FIVSLA DLL+ +LV+PF A
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 77 IYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV-MDPLRYPVLVTPVRV 135
I + W +G+VFC + TSLDV+L TASI +L ISLDRY A+ PL Y +TP+R+
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 136 AISLVLIWVISITLSFLSIHLGWNS-------RNETSKGNHTTSKCKVQVNEVYGLVDGL 188
A+ L WVI +SFL I GWN+ N ++ C VN+ Y + +
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198
Query: 189 VTFYLPLLIMCITYYRIFKVARDQAKRINHI------------SSWKAATIR---EHKAT 233
V FY+P L+M + YYRI+ A++ A +I + S+ + +T R E KA
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAA 258
Query: 234 VTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNR 293
TL +MG F +CW P+F + +V A LWLGY NS LNP LYA LN+
Sbjct: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYINSGLNPFLYAFLNK 317
Query: 294 DFRTGYQQLFCC 305
FR + + CC
Sbjct: 318 SFRRAFLIILCC 329
>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
Length = 360
Score = 209 bits (531), Expect = 5e-54
Identities = 124/312 (39%), Positives = 176/312 (56%), Gaps = 25/312 (8%)
Query: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVSLAITDLLLGLLVLPFSA 76
K+ + L+ +IL+ + GN++V +AV +R+LR + TN FIVSLA DLL+ +LV+PF A
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 77 IYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV-MDPLRYPVLVTPVRV 135
I + W +G+VFC + TSLDV+L TASI +L ISLDRY A+ PL Y +TP+R+
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 136 AISLVLIWVISITLSFLSIHLGWNS-------RNETSKGNHTTSKCKVQVNEVYGLVDGL 188
A+ L WVI +SFL I GWN+ N ++ C VN+ Y + +
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198
Query: 189 VTFYLPLLIMCITYYRIFKVARDQAKRINHI------------SSWKAATIR---EHKAT 233
V FY+P L+M + YYRI+ A++ A +I + S+ + +T R E KA
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAA 258
Query: 234 VTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNR 293
TL +MG F +CW P+F + +V A LWLGY NS LNP LYA LN+
Sbjct: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYINSGLNPFLYAFLNK 317
Query: 294 DFRTGYQQLFCC 305
FR + + CC
Sbjct: 318 SFRRAFLIILCC 329
>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
Length = 387
Score = 209 bits (531), Expect = 5e-54
Identities = 124/312 (39%), Positives = 176/312 (56%), Gaps = 25/312 (8%)
Query: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVSLAITDLLLGLLVLPFSA 76
K+ + L+ +IL+ + GN++V +AV +R+LR + TN FIVSLA DLL+ +LV+PF A
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 77 IYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV-MDPLRYPVLVTPVRV 135
I + W +G+VFC + TSLDV+L TASI +L ISLDRY A+ PL Y +TP+R+
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 136 AISLVLIWVISITLSFLSIHLGWNS-------RNETSKGNHTTSKCKVQVNEVYGLVDGL 188
A+ L WVI +SFL I GWN+ N ++ C VN+ Y + +
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198
Query: 189 VTFYLPLLIMCITYYRIFKVARDQAKRINHI------------SSWKAATIR---EHKAT 233
V FY+P L+M + YYRI+ A++ A +I + S+ + +T R E KA
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAA 258
Query: 234 VTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNR 293
TL +MG F +CW P+F + +V A LWLGY NS LNP LYA LN+
Sbjct: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYINSGLNPFLYAFLNK 317
Query: 294 DFRTGYQQLFCC 305
FR + + CC
Sbjct: 318 SFRRAFLIILCC 329
>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
Length = 378
Score = 209 bits (531), Expect = 5e-54
Identities = 124/312 (39%), Positives = 176/312 (56%), Gaps = 25/312 (8%)
Query: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVSLAITDLLLGLLVLPFSA 76
K+ + L+ +IL+ + GN++V +AV +R+LR + TN FIVSLA DLL+ +LV+PF A
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 77 IYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV-MDPLRYPVLVTPVRV 135
I + W +G+VFC + TSLDV+L TASI +L ISLDRY A+ PL Y +TP+R+
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 136 AISLVLIWVISITLSFLSIHLGWNS-------RNETSKGNHTTSKCKVQVNEVYGLVDGL 188
A+ L WVI +SFL I GWN+ N ++ C VN+ Y + +
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198
Query: 189 VTFYLPLLIMCITYYRIFKVARDQAKRINHI------------SSWKAATIR---EHKAT 233
V FY+P L+M + YYRI+ A++ A +I + S+ + +T R E KA
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAA 258
Query: 234 VTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNR 293
TL +MG F +CW P+F + +V A LWLGY NS LNP LYA LN+
Sbjct: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYINSGLNPFLYAFLNK 317
Query: 294 DFRTGYQQLFCC 305
FR + + CC
Sbjct: 318 SFRRAFLIILCC 329
>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
Length = 388
Score = 209 bits (531), Expect = 5e-54
Identities = 124/312 (39%), Positives = 176/312 (56%), Gaps = 25/312 (8%)
Query: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVSLAITDLLLGLLVLPFSA 76
K+ + L+ +IL+ + GN++V +AV +R+LR + TN FIVSLA DLL+ +LV+PF A
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 77 IYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV-MDPLRYPVLVTPVRV 135
I + W +G+VFC + TSLDV+L TASI +L ISLDRY A+ PL Y +TP+R+
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 136 AISLVLIWVISITLSFLSIHLGWNS-------RNETSKGNHTTSKCKVQVNEVYGLVDGL 188
A+ L WVI +SFL I GWN+ N ++ C VN+ Y + +
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198
Query: 189 VTFYLPLLIMCITYYRIFKVARDQAKRINHI------------SSWKAATIR---EHKAT 233
V FY+P L+M + YYRI+ A++ A +I + S+ + +T R E KA
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAA 258
Query: 234 VTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNR 293
TL +MG F +CW P+F + +V A LWLGY NS LNP LYA LN+
Sbjct: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYINSGLNPFLYAFLNK 317
Query: 294 DFRTGYQQLFCC 305
FR + + CC
Sbjct: 318 SFRRAFLIILCC 329
>gi|4503383 dopamine receptor D1 [Homo sapiens]
Length = 446
Score = 207 bits (528), Expect = 1e-53
Identities = 126/367 (34%), Positives = 193/367 (52%), Gaps = 44/367 (11%)
Query: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRN-LTNCFIVSLAITDLLLGLLVLPFSA 76
+I L++LIL T+ GN +VC AV R LR+ +TN F++SLA++DLL+ +LV+P+ A
Sbjct: 23 RILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKA 82
Query: 77 IYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVA 136
+ +++ W FG FCNI+ + D+M TASILNL +IS+DRY A+ P RY +TP
Sbjct: 83 VAEIAGFWPFGS-FCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAF 141
Query: 137 ISLVLIWVISITLSFLSIHLGWNSRNETSKGN-------HTTSKCKVQVNEVYGLVDGLV 189
I + + W +S+ +SF+ + L W+ TS + T C ++ Y + ++
Sbjct: 142 ILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVI 201
Query: 190 TFYLPLLIMCITYYRIFKVARDQAKRINHI--------------------------SSWK 223
+FY+P+ IM +TY RI+++A+ Q +RI + SS+K
Sbjct: 202 SFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFK 261
Query: 224 AATIREHKATVTLAAVMGAFIICWFPYF-----TAFVYRGLRGDDAINEVLEAIVLWLGY 278
+ RE K TL+ +MG F+ CW P+F F G I+ + +W G+
Sbjct: 262 MSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGW 321
Query: 279 ANSALNPILYAALNRDFRTGYQQLF-CCRL--ANRNSHKTSLRSNASQLSRTQSREPRQQ 335
ANS+LNPI+Y A N DFR + L C RL A N+ +T +N + EPR
Sbjct: 322 ANSSLNPIIY-AFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGS 380
Query: 336 EEKPLKL 342
K L
Sbjct: 381 ISKECNL 387
>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
Length = 413
Score = 205 bits (521), Expect = 7e-53
Identities = 111/351 (31%), Positives = 188/351 (53%), Gaps = 27/351 (7%)
Query: 23 VVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSC 82
+V+++++L V GNV+V A+ RL+ +TN FI SLA DL++GL V+PF A + L
Sbjct: 38 IVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMK 97
Query: 83 KWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLI 142
W+FG +C +TS+DV+ TASI L +I++DRY A+ P +Y L+T + + ++++
Sbjct: 98 MWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMV 157
Query: 143 WVISITLSFLSIHLGWNSRNETSKGNHTTSK--CKVQVNEVYGLVDGLVTFYLPLLIMCI 200
W++S SFL I + W N ++ C N+ Y + +V+FY+PL+IM
Sbjct: 158 WIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVF 217
Query: 201 TYYRIFKVARDQAKRIN------HISSWKAA----------------TIREHKATVTLAA 238
Y R+F+ A+ Q ++I+ H+ + ++EHKA TL
Sbjct: 218 VYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGI 277
Query: 239 VMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTG 298
+MG F +CW P+F + ++ D+ I + + ++ W+GY NS NP++Y + DFR
Sbjct: 278 IMGTFTLCWLPFFIVNIVHVIQ-DNLIRKEVYILLNWIGYVNSGFNPLIYCR-SPDFRIA 335
Query: 299 YQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTE 349
+Q+L C R ++ ++ SN + Q++E L + GTE
Sbjct: 336 FQELLCLRRSSLKAYGNGYSSNGN-TGEQSGYHVEQEKENKLLCEDLPGTE 385
>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
Length = 402
Score = 204 bits (518), Expect = 1e-52
Identities = 125/326 (38%), Positives = 179/326 (54%), Gaps = 39/326 (11%)
Query: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVSLAITDLLLGLLVLPFSA 76
K+ + L+ +IL+ + GN++V +AV +R+LR + TN FIVSLA DLL+ +LV+PF A
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 77 IYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV-MDPLRYPVLVTPVRV 135
I + W +G+VFC + TSLDV+L TASI +L ISLDRY A+ PL Y +TP+R+
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 136 AISLVLIWVISITLSFLSIHLGWNS------RNETSKG---------------NHTTSKC 174
A+ L WVI +SFL I GWN+ ++G N ++ C
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYC 198
Query: 175 KVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHI------------SSW 222
VN+ Y + +V FY+P L+M + YYRI+ A++ A +I + S+
Sbjct: 199 VFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSAD 258
Query: 223 KAATIR---EHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYA 279
+ +T R E KA TL +MG F +CW P+F + +V A LWLGY
Sbjct: 259 QHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYI 317
Query: 280 NSALNPILYAALNRDFRTGYQQLFCC 305
NS LNP LYA LN+ FR + + CC
Sbjct: 318 NSGLNPFLYAFLNKSFRRAFLIILCC 343
>gi|4557265 beta-1-adrenergic receptor [Homo sapiens]
Length = 477
Score = 202 bits (515), Expect = 3e-52
Identities = 122/344 (35%), Positives = 176/344 (51%), Gaps = 53/344 (15%)
Query: 23 VVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSC 82
+++A+++L+ VAGNV+V +A+ RL+ LTN FI+SLA DL++GLLV+PF A +
Sbjct: 63 LLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWG 122
Query: 83 KWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLI 142
+W +G FC ++TS+DV+ TASI L +I+LDRY A+ P RY L+T R + +
Sbjct: 123 RWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVCTV 182
Query: 143 WVISITLSFLSIHLGW--NSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCI 200
W IS +SFL I + W +E + + C N Y + +V+FY+PL IM
Sbjct: 183 WAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAF 242
Query: 201 TYYRIFKVARDQAKRINHIS------------------------------SWKAAT---- 226
Y R+F+ A+ Q K+I+ + AAT
Sbjct: 243 VYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAPLA 302
Query: 227 --------------IREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAI 272
+RE KA TL +MG F +CW P+F A V + + + + L
Sbjct: 303 NGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFH-RELVPDRLFVF 361
Query: 273 VLWLGYANSALNPILYAALNRDFRTGYQQLFCC-RLANRNSHKT 315
WLGYANSA NPI+Y + DFR +Q L CC R A R H T
Sbjct: 362 FNWLGYANSAFNPIIYCR-SPDFRKAFQGLLCCARRAARRRHAT 404
>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
Length = 520
Score = 201 bits (511), Expect = 1e-51
Identities = 134/419 (31%), Positives = 205/419 (48%), Gaps = 74/419 (17%)
Query: 3 PNGTASSFCL---DSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVS 59
PN T+S+ L D T I++ +VL IL + GN++V L+V NR LR TN FIV+
Sbjct: 28 PNQTSSNSTLPQLDITRA-ISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVN 86
Query: 60 LAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCA 119
LA+ DLLL VLPFSA ++ W G++FC+I+ ++DV+ CTASIL+L IS+DRY
Sbjct: 87 LAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIG 146
Query: 120 VMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVN 179
V L+YP LVT + ++L+ +WV+S +S + LGW + +C V
Sbjct: 147 VRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPL-LGWK-----EPAPNDDKECGVTEE 200
Query: 180 EVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRI-----NHISSWKAATIREH---- 230
Y L L +FY+PL ++ + Y R++ VA+ K + +S+ K T+R H
Sbjct: 201 PFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNF 260
Query: 231 ------------------------------KATVTLAAVMGAFIICWFPYFTAF----VY 256
KA TL V+G FI+CW P+F A ++
Sbjct: 261 HEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLF 320
Query: 257 RGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTS 316
L+ DA+ +V V WLGY NS LNPI+Y +++F+ + ++ C+ R +
Sbjct: 321 STLKPPDAVFKV----VFWLGYFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRGRRRRR 376
Query: 317 LR-------------SNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDRPWL 362
R + L R+QSR+ + SG++ T P + +L
Sbjct: 377 RRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSG----SCLSGSQRTLPSASPSPGYL 431
>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
Length = 455
Score = 201 bits (510), Expect = 1e-51
Identities = 122/359 (33%), Positives = 185/359 (51%), Gaps = 48/359 (13%)
Query: 1 MAPNGTASSFCLDSTAC-----KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNC 55
++ N + SS C A I + V+L LIL V GN++V L+V +R L ++T+
Sbjct: 4 LSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHY 63
Query: 56 FIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLD 115
+IV+LA+ DLLL VLPFSAI+++ W+FG+VFCNI+ ++DV+ CTASI+ L +IS+D
Sbjct: 64 YIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISID 123
Query: 116 RYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCK 175
RY V PLRYP +VT R ++L+ +W +S+ +S + GW + C+
Sbjct: 124 RYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPL-FGWR-----QPAPEDETICQ 177
Query: 176 VQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQ----------------------- 212
+ Y L L +FYLPL I+ + Y R++ VA+ +
Sbjct: 178 INEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIH 237
Query: 213 -------------AKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGL 259
AK H S RE KA TL V+G F++CW P+F
Sbjct: 238 RKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSF 297
Query: 260 RGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCR-LANRNSHKTSL 317
D +E + IV WLGY NS +NPI+Y +++F+ +Q + + L + S K +L
Sbjct: 298 FPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHAL 356
>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
Length = 466
Score = 201 bits (510), Expect = 1e-51
Identities = 122/359 (33%), Positives = 185/359 (51%), Gaps = 48/359 (13%)
Query: 1 MAPNGTASSFCLDSTAC-----KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNC 55
++ N + SS C A I + V+L LIL V GN++V L+V +R L ++T+
Sbjct: 4 LSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHY 63
Query: 56 FIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLD 115
+IV+LA+ DLLL VLPFSAI+++ W+FG+VFCNI+ ++DV+ CTASI+ L +IS+D
Sbjct: 64 YIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISID 123
Query: 116 RYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCK 175
RY V PLRYP +VT R ++L+ +W +S+ +S + GW + C+
Sbjct: 124 RYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPL-FGWR-----QPAPEDETICQ 177
Query: 176 VQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQ----------------------- 212
+ Y L L +FYLPL I+ + Y R++ VA+ +
Sbjct: 178 INEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIH 237
Query: 213 -------------AKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGL 259
AK H S RE KA TL V+G F++CW P+F
Sbjct: 238 RKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSF 297
Query: 260 RGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCR-LANRNSHKTSL 317
D +E + IV WLGY NS +NPI+Y +++F+ +Q + + L + S K +L
Sbjct: 298 FPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHAL 356
>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
Length = 475
Score = 201 bits (510), Expect = 1e-51
Identities = 122/359 (33%), Positives = 185/359 (51%), Gaps = 48/359 (13%)
Query: 1 MAPNGTASSFCLDSTAC-----KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNC 55
++ N + SS C A I + V+L LIL V GN++V L+V +R L ++T+
Sbjct: 4 LSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHY 63
Query: 56 FIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLD 115
+IV+LA+ DLLL VLPFSAI+++ W+FG+VFCNI+ ++DV+ CTASI+ L +IS+D
Sbjct: 64 YIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISID 123
Query: 116 RYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCK 175
RY V PLRYP +VT R ++L+ +W +S+ +S + GW + C+
Sbjct: 124 RYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPL-FGWR-----QPAPEDETICQ 177
Query: 176 VQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQ----------------------- 212
+ Y L L +FYLPL I+ + Y R++ VA+ +
Sbjct: 178 INEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIH 237
Query: 213 -------------AKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGL 259
AK H S RE KA TL V+G F++CW P+F
Sbjct: 238 RKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSF 297
Query: 260 RGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCR-LANRNSHKTSL 317
D +E + IV WLGY NS +NPI+Y +++F+ +Q + + L + S K +L
Sbjct: 298 FPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHAL 356
>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
Length = 429
Score = 201 bits (510), Expect = 1e-51
Identities = 122/359 (33%), Positives = 185/359 (51%), Gaps = 48/359 (13%)
Query: 1 MAPNGTASSFCLDSTAC-----KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNC 55
++ N + SS C A I + V+L LIL V GN++V L+V +R L ++T+
Sbjct: 4 LSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHY 63
Query: 56 FIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLD 115
+IV+LA+ DLLL VLPFSAI+++ W+FG+VFCNI+ ++DV+ CTASI+ L +IS+D
Sbjct: 64 YIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISID 123
Query: 116 RYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCK 175
RY V PLRYP +VT R ++L+ +W +S+ +S + GW + C+
Sbjct: 124 RYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPL-FGWR-----QPAPEDETICQ 177
Query: 176 VQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQ----------------------- 212
+ Y L L +FYLPL I+ + Y R++ VA+ +
Sbjct: 178 INEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIH 237
Query: 213 -------------AKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGL 259
AK H S RE KA TL V+G F++CW P+F
Sbjct: 238 RKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSF 297
Query: 260 RGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCR-LANRNSHKTSL 317
D +E + IV WLGY NS +NPI+Y +++F+ +Q + + L + S K +L
Sbjct: 298 FPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHAL 356
>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
Length = 572
Score = 199 bits (505), Expect = 5e-51
Identities = 117/353 (33%), Positives = 182/353 (51%), Gaps = 48/353 (13%)
Query: 4 NGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAIT 63
NGTA+ L +A + + V LA IL+ VAGN++V L+V NR L+ +TN FIV+LA+
Sbjct: 82 NGTAAVGGLVVSAQGVGVGVFLAAFILMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVA 141
Query: 64 DLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDP 123
DLLL VLPFSA ++ W+FG+ FC+++ ++DV+ CTASIL+L IS+DRY V
Sbjct: 142 DLLLSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHS 201
Query: 124 LRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYG 183
L+YP ++T + A L L+WV+++ +S + LGW + C + Y
Sbjct: 202 LKYPAIMTERKAAAILALLWVVALVVSVGPL-LGWKEPVPPDE-----RFCGITEEAGYA 255
Query: 184 LVDGLVTFYLPLLIMCITYYRIFKVARDQAKRIN---------------HISSWKAAT-- 226
+ + +FYLP+ ++ + Y R++ VAR + + I AAT
Sbjct: 256 VFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGA 315
Query: 227 -------------------------IREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRG 261
RE KA TLA V+G F++CWFP+F L
Sbjct: 316 DGAHGMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFP 375
Query: 262 DDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHK 314
+E + ++ WLGY NS +NP++Y +R+F+ + +L C+ R +
Sbjct: 376 QLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRRR 428
>gi|4503391 dopamine receptor D5 [Homo sapiens]
Length = 477
Score = 197 bits (501), Expect = 1e-50
Identities = 113/338 (33%), Positives = 181/338 (53%), Gaps = 52/338 (15%)
Query: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLR-NLTNCFIVSLAITDLLLGLLVLPFSA 76
++ +L +LI+ T+ GNV+VC A+ +R LR N+TN FIVSLA++DL + LLV+P+ A
Sbjct: 40 QVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKA 99
Query: 77 IYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVA 136
+ +++ W FG FC+++ + D+M TASILNL +IS+DRY A+ P RY +T
Sbjct: 100 VAEVAGYWPFG-AFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMAL 158
Query: 137 ISLVLIWVISITLSFLSIHLGWNSRNETSKG---------------------NHTTSKCK 175
+ + L W +SI +SF+ + L W+ S G + C
Sbjct: 159 VMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCD 218
Query: 176 VQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHI---------------- 219
+N Y + L++FY+P+ IM +TY RI+++A+ Q +RI+ +
Sbjct: 219 SSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAAC 278
Query: 220 ---SSWKAATIREHKATVTLAAVMGAFIICWFPYF-----TAFVYRGLRGDDA----INE 267
+S +A+ +E K TL+ +MG F+ CW P+F F G A ++E
Sbjct: 279 APDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSE 338
Query: 268 VLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCC 305
+ +W G+ANS+LNP++Y A N DF+ + QL C
Sbjct: 339 TTFDVFVWFGWANSSLNPVIY-AFNADFQKVFAQLLGC 375
>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
Length = 408
Score = 192 bits (489), Expect = 3e-49
Identities = 119/344 (34%), Positives = 177/344 (51%), Gaps = 42/344 (12%)
Query: 1 MAPNGTASSFCLDSTACKITIT-VVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVS 59
+APN TA++ L + + +LA+ +L TV GN++V +A+ RL+ +TN F+ S
Sbjct: 20 LAPN-TANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIVAIAWTPRLQTMTNVFVTS 78
Query: 60 LAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCA 119
LA DL++GLLV+P +A L+ W G C ++TS+DV+ TASI L +++DRY A
Sbjct: 79 LAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLA 138
Query: 120 VMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGW---NSRNETSKGNHTTSKCKV 176
V +PLRY LVT ++VL+WV+S +SF I W + E + + C
Sbjct: 139 VTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRVGADAEAQRCHSNPRCCAF 198
Query: 177 QVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRI-----------------NHI 219
N Y L+ V+FYLPLL+M Y R+F VA Q + + +
Sbjct: 199 ASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRGELGRFPPEESPPAPSRSL 258
Query: 220 SSWKAAT-------------------IREHKATVTLAAVMGAFIICWFPYFTAFVYRGLR 260
+ T +REH+A TL +MG F +CW P+F A V R L
Sbjct: 259 APAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGTFTLCWLPFFLANVLRALG 318
Query: 261 GDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFC 304
G + + WLGYANSA NP++Y + DFR+ +++L C
Sbjct: 319 GPSLVPGPAFLALNWLGYANSAFNPLIYCR-SPDFRSAFRRLLC 361
>gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]
Length = 432
Score = 184 bits (466), Expect = 2e-46
Identities = 110/334 (32%), Positives = 167/334 (50%), Gaps = 47/334 (14%)
Query: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAI 77
K+ I +L ++ L+T+AGN +V ++V ++LR +N IVSLA+ DL + + V+PF ++
Sbjct: 81 KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSV 140
Query: 78 YQL-SCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVA 136
L KW FG FCN++ ++DVM CTASI+ L +IS+DRY + PL YPV +A
Sbjct: 141 TDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMA 200
Query: 137 ISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLL 196
++ +W++S +++ + GW K C + + Y + V FY+P+
Sbjct: 201 KMILSVWLLSASITLPPL-FGWAQNVNDDK------VCLISQDFGYTIYSTAVAFYIPMS 253
Query: 197 IMCITYYRIFKVARDQAKR------------------------------------INHIS 220
+M YY+I+K AR A + + H
Sbjct: 254 VMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHER 313
Query: 221 SWKAATIREHKATVTLAAVMGAFIICWFPYF---TAFVYRGLRGDDAINEVLEAIVLWLG 277
+ RE KA TL ++GAF +CW P+F TA + I +E LWLG
Sbjct: 314 KNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLG 373
Query: 278 YANSALNPILYAALNRDFRTGYQQLFCCRLANRN 311
YANS +NP +YA NRD RT Y+ L C+ N N
Sbjct: 374 YANSLINPFIYAFFNRDLRTTYRSLLQCQYRNIN 407
>gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]
Length = 479
Score = 184 bits (466), Expect = 2e-46
Identities = 110/334 (32%), Positives = 167/334 (50%), Gaps = 47/334 (14%)
Query: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAI 77
K+ I +L ++ L+T+AGN +V ++V ++LR +N IVSLA+ DL + + V+PF ++
Sbjct: 81 KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSV 140
Query: 78 YQL-SCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVA 136
L KW FG FCN++ ++DVM CTASI+ L +IS+DRY + PL YPV +A
Sbjct: 141 TDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMA 200
Query: 137 ISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLL 196
++ +W++S +++ + GW K C + + Y + V FY+P+
Sbjct: 201 KMILSVWLLSASITLPPL-FGWAQNVNDDK------VCLISQDFGYTIYSTAVAFYIPMS 253
Query: 197 IMCITYYRIFKVARDQAKR------------------------------------INHIS 220
+M YY+I+K AR A + + H
Sbjct: 254 VMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHER 313
Query: 221 SWKAATIREHKATVTLAAVMGAFIICWFPYF---TAFVYRGLRGDDAINEVLEAIVLWLG 277
+ RE KA TL ++GAF +CW P+F TA + I +E LWLG
Sbjct: 314 KNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLG 373
Query: 278 YANSALNPILYAALNRDFRTGYQQLFCCRLANRN 311
YANS +NP +YA NRD RT Y+ L C+ N N
Sbjct: 374 YANSLINPFIYAFFNRDLRTTYRSLLQCQYRNIN 407
>gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]
Length = 445
Score = 184 bits (466), Expect = 2e-46
Identities = 110/334 (32%), Positives = 167/334 (50%), Gaps = 47/334 (14%)
Query: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAI 77
K+ I +L ++ L+T+AGN +V ++V ++LR +N IVSLA+ DL + + V+PF ++
Sbjct: 81 KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSV 140
Query: 78 YQL-SCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVA 136
L KW FG FCN++ ++DVM CTASI+ L +IS+DRY + PL YPV +A
Sbjct: 141 TDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMA 200
Query: 137 ISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLL 196
++ +W++S +++ + GW K C + + Y + V FY+P+
Sbjct: 201 KMILSVWLLSASITLPPL-FGWAQNVNDDK------VCLISQDFGYTIYSTAVAFYIPMS 253
Query: 197 IMCITYYRIFKVARDQAKR------------------------------------INHIS 220
+M YY+I+K AR A + + H
Sbjct: 254 VMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHER 313
Query: 221 SWKAATIREHKATVTLAAVMGAFIICWFPYF---TAFVYRGLRGDDAINEVLEAIVLWLG 277
+ RE KA TL ++GAF +CW P+F TA + I +E LWLG
Sbjct: 314 KNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLG 373
Query: 278 YANSALNPILYAALNRDFRTGYQQLFCCRLANRN 311
YANS +NP +YA NRD RT Y+ L C+ N N
Sbjct: 374 YANSLINPFIYAFFNRDLRTTYRSLLQCQYRNIN 407
>gi|21264324 trace amine associated receptor 1 [Homo sapiens]
Length = 339
Score = 180 bits (456), Expect = 2e-45
Identities = 102/316 (32%), Positives = 167/316 (52%), Gaps = 13/316 (4%)
Query: 14 STACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLP 73
S + ++ ++ ++IL T+ GN++V +++ ++L TN I S+A D LLG LV+P
Sbjct: 19 SNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMP 78
Query: 74 FSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPV 133
+S + W FG+VFC I+TS D+ML +ASI +L IS+DRY AV DPLRY + +
Sbjct: 79 YSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNIL 138
Query: 134 RVAISLVLIWVISITLSFLSIHLGWNSRNETS---KGNHTTSKCKVQVNEVYGLVDGLVT 190
+ + + + W + +F I L N + K H C V +++ G++ + +
Sbjct: 139 VICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTS 198
Query: 191 FYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATI---------REHKATVTLAAVMG 241
FY+P IM YYRI+ +A++QA+ I+ + + +E KA TL VMG
Sbjct: 199 FYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMG 258
Query: 242 AFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQ 301
F+ICW P+F V I L +++W GY NS NP++YA FR +
Sbjct: 259 VFLICWCPFFICTVMDPFL-HYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKM 317
Query: 302 LFCCRLANRNSHKTSL 317
+ ++ ++S + L
Sbjct: 318 MLFGKIFQKDSSRCKL 333
>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
sapiens]
Length = 440
Score = 178 bits (451), Expect = 9e-45
Identities = 118/370 (31%), Positives = 185/370 (50%), Gaps = 42/370 (11%)
Query: 21 ITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQL 80
+ L V+I +T A N ++ + LRN +N F+VSL +DL++GL+V+P + + L
Sbjct: 29 VAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNAL 88
Query: 81 SCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLV 140
+W + C ++T+ DVM C+ASILNL +ISLDRY ++ PLRY + +TP+R A++LV
Sbjct: 89 YGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLR-ALALV 147
Query: 141 L-IWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMC 199
L W ++ SFL + LGW+ +C++ + + LV +TF+LP +C
Sbjct: 148 LGAWSLAALASFLPLLLGWHELGHARP--PVPGQCRLLASLPFVLVASGLTFFLPSGAIC 205
Query: 200 ITYYRIFKVARDQAKRINHISSWKAATIREH----------------------------K 231
TY RI AR QA ++ +++ A+ E K
Sbjct: 206 FTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSRKALK 265
Query: 232 ATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAAL 291
A++TL ++G F + W P+F A + + + D I+ L ++ WLGY NS +NPI+Y
Sbjct: 266 ASLTLGILLGMFFVTWLPFFVANIVQAV--CDCISPGLFDVLTWLGYCNSTMNPIIYPLF 323
Query: 292 NRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQ----QEEKPLKLQVWSG 347
RDF+ + C R S AS RT PR Q+ PL L S
Sbjct: 324 MRDFKRALGRFLPCPRCPRERQ----ASLASPSLRTSHSGPRPGLSLQQVLPLPLPPDSD 379
Query: 348 TEVTAPQGAT 357
++ A G +
Sbjct: 380 SDSDAGSGGS 389
>gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo
sapiens]
Length = 366
Score = 176 bits (447), Expect = 3e-44
Identities = 110/355 (30%), Positives = 170/355 (47%), Gaps = 66/355 (18%)
Query: 12 LDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLV 71
L+ KI +++ L+ L L+T N +V A+ + R+L + N I SLA+TD L+ +LV
Sbjct: 17 LNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLV 76
Query: 72 LPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVT 131
+PFS +Y + W G+V C+I+ S+D+ CT SIL+L I+LDRY A+ D + Y T
Sbjct: 77 MPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRT 136
Query: 132 PVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTF 191
P I + ++W+IS+ +S L W + TS+ + K V+ +Y F
Sbjct: 137 PKHAGIMITIVWIISVFISMPP--LFWRHQG-TSRDDECIIKHDHIVSTIYSTFG---AF 190
Query: 192 YLPLLIMCITYYRIFKVARD-----QAKRI------------------------------ 216
Y+PL ++ I YY+I++ A+ QA RI
Sbjct: 191 YIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKSVSTSYVLEKS 250
Query: 217 ----------------------NHISSWKAATI---REHKATVTLAAVMGAFIICWFPYF 251
H SW+ I RE KA TL ++GAF+ICW P+F
Sbjct: 251 LSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFF 310
Query: 252 TAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCR 306
+ + I+E + + WLGY NS +NP++Y N DF+ +Q+L CR
Sbjct: 311 VKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCR 365
>gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo
sapiens]
Length = 377
Score = 175 bits (444), Expect = 6e-44
Identities = 113/348 (32%), Positives = 167/348 (47%), Gaps = 60/348 (17%)
Query: 16 ACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFS 75
A KI++ VVL+V+ L TV N V + L R+L N I SLA TDLL+ +LV+P S
Sbjct: 36 ALKISLAVVLSVITLATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPIS 95
Query: 76 AIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRV 135
Y ++ W+FG++ C+I+ S D+ CTASIL+L +I+LDRY A+ D L Y T
Sbjct: 96 IAYTITHTWNFGQILCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHA 155
Query: 136 AISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEV-YGLVDGLVTFYLP 194
A + ++W ISI +S L W +K S C V +++ Y + FY+P
Sbjct: 156 ATMIAIVWAISICISIPP--LFWRQ----AKAQEEMSDCLVNTSQISYTIYSTCGAFYIP 209
Query: 195 LLIMCITYYRIFKVARDQ--------AKR------------------------------- 215
+++ I Y RI++ AR++ KR
Sbjct: 210 SVLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNSSLHEGHSHSAG 269
Query: 216 ----INHI---------SSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGD 262
NH+ + + RE KAT L ++GAFIICW P+F + + D
Sbjct: 270 SPLFFNHVKIKLADSALERKRISAARERKATKILGIILGAFIICWLPFFVVSLVLPICRD 329
Query: 263 DA-INEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLAN 309
I+ L WLGY NS +NPI+Y N +FR +Q++ R A+
Sbjct: 330 SCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKIVPFRKAS 377
>gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo
sapiens]
Length = 390
Score = 160 bits (406), Expect = 1e-39
Identities = 100/341 (29%), Positives = 158/341 (46%), Gaps = 62/341 (18%)
Query: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAI 77
K+ + ++LA++ L T N V V R+L N I SLA+TDLL+ +LV+P S +
Sbjct: 49 KVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTM 108
Query: 78 YQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAI 137
Y ++ +W+ G+V C+ + S D+ CTASIL+L +I+LDRY A+ D + Y TP R A+
Sbjct: 109 YTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAV 168
Query: 138 SLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEV-YGLVDGLVTFYLPLL 196
+ L+WV SI++S W +K S+C V + + Y + + FY P L
Sbjct: 169 MIALVWVFSISISLPPFF--WRQ----AKAEEEVSECVVNTDHILYTVYSTVGAFYFPTL 222
Query: 197 IMCITYYRIFKVARDQAKR----------------------------------------- 215
++ Y RI+ AR + +
Sbjct: 223 LLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESG 282
Query: 216 ----INHISSWKAATIREHK---------ATVTLAAVMGAFIICWFPYFTAFVYRGLRGD 262
+N + + + E K AT TL ++GAFI+CW P+F + + D
Sbjct: 283 SPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKD 342
Query: 263 DA-INEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQL 302
+ + WLGY NS +NPI+Y N DF+ + +L
Sbjct: 343 ACWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKL 383
>gi|4504537 5-hydroxytryptamine (serotonin) receptor 1E [Homo
sapiens]
Length = 365
Score = 157 bits (396), Expect = 2e-38
Identities = 104/347 (29%), Positives = 164/347 (47%), Gaps = 64/347 (18%)
Query: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAI 77
K+ I + L V+ +T N+ V +A+G ++L N I SLA+TDLL+ +LV+P S I
Sbjct: 22 KMLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQPANYLICSLAVTDLLVAVLVMPLSII 81
Query: 78 YQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAI 137
Y + +W G C ++ S+D+ CT SIL+L +I+LDRY A+ + + Y T R A+
Sbjct: 82 YIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAKRAAL 141
Query: 138 SLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEV-YGLVDGLVTFYLPLL 196
++ +W ISI +S L W S S S+C +Q + V Y + L FY+PL
Sbjct: 142 MILTVWTISIFISMPP--LFWRSHRRLSP---PPSQCTIQHDHVIYTIYSTLGAFYIPLT 196
Query: 197 IMCITYYRIFKVA------RDQAKRINHISSWKAATIREHKATVTL-------------- 236
++ I YYRI+ A R ++ +++ S+ + K T T
Sbjct: 197 LILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQNSFASCKLTQTFCVSDFSTSDPTTEF 256
Query: 237 ---------------------------------AAVMG----AFIICWFPYFTAFVYRGL 259
A ++G AFI+ W P+F + GL
Sbjct: 257 EKFHASIRIPPFDNDLDHPGERQQISSTRERKAARILGLILGAFILSWLPFFIKELIVGL 316
Query: 260 RGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCR 306
+EV + + WLGY NS +NP+LY + N DF+ +++L CR
Sbjct: 317 SIYTVSSEVAD-FLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIRCR 362
>gi|223633986 trace amine associated receptor 5 [Homo sapiens]
Length = 337
Score = 155 bits (393), Expect = 5e-38
Identities = 101/283 (35%), Positives = 149/283 (52%), Gaps = 7/283 (2%)
Query: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAI 77
++ I + A +LI V GNV V AV + L TN ++SLA+ D+ LGLLVLP S I
Sbjct: 34 QLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLSLALADMFLGLLVLPLSTI 93
Query: 78 YQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAI 137
+ W FG C ++T LD + C SI +L IS+DR+CA+ DPL YP T VRVA+
Sbjct: 94 RSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFT-VRVAL 152
Query: 138 SLVLI-WVI--SITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLP 194
+L W + + T FL + ++ + C++ +N+ +G ++ F++P
Sbjct: 153 RYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGSCQLLLNKFWGWLN-FPLFFVP 211
Query: 195 LLIMCITYYRIFKVARDQAKRINHIS-SWKAATIREHKATVTLAAVMGAFIICWFPYFTA 253
LIM Y +IF VA QA++I +S S A E KA TL +G +++CW P+
Sbjct: 212 CLIMISLYVKIFVVATRQAQQITTLSKSLAGAAKHERKAAKTLGIAVGIYLLCWLPFTID 271
Query: 254 FVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFR 296
+ L V + I +W Y NSA NPI+Y + FR
Sbjct: 272 TMVDSLLHFITPPLVFD-IFIWFAYFNSACNPIIYVFSYQWFR 313
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.138 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,837,426
Number of Sequences: 37866
Number of extensions: 545495
Number of successful extensions: 3737
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 503
Number of HSP's successfully gapped in prelim test: 244
Number of HSP's that attempted gapping in prelim test: 2017
Number of HSP's gapped (non-prelim): 995
length of query: 397
length of database: 18,247,518
effective HSP length: 104
effective length of query: 293
effective length of database: 14,309,454
effective search space: 4192670022
effective search space used: 4192670022
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.