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Search of human proteins with 196114967
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|196114967 protein tyrosine phosphatase, non-receptor type 12
isoform 2 [Homo sapiens]
(661 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|196114967 protein tyrosine phosphatase, non-receptor type 12 ... 1365 0.0
gi|196114951 protein tyrosine phosphatase, non-receptor type 12 ... 1365 0.0
gi|196114970 protein tyrosine phosphatase, non-receptor type 12 ... 1343 0.0
gi|224586931 protein tyrosine phosphatase, non-receptor type 22 ... 275 7e-74
gi|224586929 protein tyrosine phosphatase, non-receptor type 22 ... 275 7e-74
gi|18375655 protein tyrosine phosphatase, non-receptor type 18 i... 176 8e-44
gi|215277017 protein tyrosine phosphatase, non-receptor type 18 ... 146 5e-35
gi|18104993 protein tyrosine phosphatase, non-receptor type 6 is... 127 4e-29
gi|148539860 protein tyrosine phosphatase, receptor type, T isof... 122 1e-27
gi|148539858 protein tyrosine phosphatase, receptor type, T isof... 122 1e-27
gi|208431815 protein tyrosine phosphatase, receptor type, K isof... 121 2e-27
gi|18860902 protein tyrosine phosphatase, receptor type, K isofo... 121 2e-27
gi|18104989 protein tyrosine phosphatase, non-receptor type 6 is... 121 2e-27
gi|18104991 protein tyrosine phosphatase, non-receptor type 6 is... 121 2e-27
gi|4506301 protein tyrosine phosphatase, non-receptor type 9 [Ho... 117 3e-26
gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Ho... 116 6e-26
gi|13677222 receptor-type protein tyrosine phosphatase O isoform... 115 1e-25
gi|13677220 receptor-type protein tyrosine phosphatase O isoform... 115 1e-25
gi|13677218 receptor-type protein tyrosine phosphatase O isoform... 115 1e-25
gi|13677216 receptor-type protein tyrosine phosphatase O isoform... 115 1e-25
gi|13677214 receptor-type protein tyrosine phosphatase O isoform... 115 1e-25
gi|4506323 receptor-type protein tyrosine phosphatase O isoform ... 115 1e-25
gi|157419150 protein tyrosine phosphatase, receptor type, M isof... 115 2e-25
gi|157419152 protein tyrosine phosphatase, receptor type, M isof... 115 2e-25
gi|18450371 protein tyrosine phosphatase, receptor type, A isofo... 114 2e-25
gi|4506303 protein tyrosine phosphatase, receptor type, A isofor... 114 2e-25
gi|18450369 protein tyrosine phosphatase, receptor type, A isofo... 114 2e-25
gi|241896926 protein tyrosine phosphatase, receptor type, H isof... 114 3e-25
gi|241896924 protein tyrosine phosphatase, receptor type, H isof... 114 3e-25
gi|148728162 protein tyrosine phosphatase, receptor type, J isof... 110 5e-24
>gi|196114967 protein tyrosine phosphatase, non-receptor type 12
isoform 2 [Homo sapiens]
Length = 661
Score = 1365 bits (3533), Expect = 0.0
Identities = 661/661 (100%), Positives = 661/661 (100%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL
Sbjct: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
Query: 61 LEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTG 120
LEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTG
Sbjct: 61 LEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTG 120
Query: 121 AICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQ 180
AICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQ
Sbjct: 121 AICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQ 180
Query: 181 LYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEP 240
LYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEP
Sbjct: 181 LYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEP 240
Query: 241 HPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKN 300
HPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKN
Sbjct: 241 HPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKN 300
Query: 301 ESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQ 360
ESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQ
Sbjct: 301 ESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQ 360
Query: 361 ELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFH 420
ELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFH
Sbjct: 361 ELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFH 420
Query: 421 GPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTN 480
GPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTN
Sbjct: 421 GPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTN 480
Query: 481 PLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTT 540
PLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTT
Sbjct: 481 PLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTT 540
Query: 541 HSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITS 600
HSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITS
Sbjct: 541 HSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITS 600
Query: 601 ENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEW 660
ENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEW
Sbjct: 601 ENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEW 660
Query: 661 T 661
T
Sbjct: 661 T 661
>gi|196114951 protein tyrosine phosphatase, non-receptor type 12
isoform 1 [Homo sapiens]
Length = 780
Score = 1365 bits (3533), Expect = 0.0
Identities = 661/661 (100%), Positives = 661/661 (100%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL
Sbjct: 120 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 179
Query: 61 LEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTG 120
LEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTG
Sbjct: 180 LEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTG 239
Query: 121 AICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQ 180
AICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQ
Sbjct: 240 AICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQ 299
Query: 181 LYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEP 240
LYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEP
Sbjct: 300 LYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEP 359
Query: 241 HPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKN 300
HPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKN
Sbjct: 360 HPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKN 419
Query: 301 ESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQ 360
ESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQ
Sbjct: 420 ESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQ 479
Query: 361 ELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFH 420
ELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFH
Sbjct: 480 ELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFH 539
Query: 421 GPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTN 480
GPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTN
Sbjct: 540 GPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTN 599
Query: 481 PLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTT 540
PLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTT
Sbjct: 600 PLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTT 659
Query: 541 HSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITS 600
HSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITS
Sbjct: 660 HSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITS 719
Query: 601 ENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEW 660
ENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEW
Sbjct: 720 ENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEW 779
Query: 661 T 661
T
Sbjct: 780 T 780
>gi|196114970 protein tyrosine phosphatase, non-receptor type 12
isoform 3 [Homo sapiens]
Length = 650
Score = 1343 bits (3475), Expect = 0.0
Identities = 650/650 (100%), Positives = 650/650 (100%)
Query: 12 MACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLLEFQNESRRLY 71
MACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLLEFQNESRRLY
Sbjct: 1 MACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLLEFQNESRRLY 60
Query: 72 QFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNL 131
QFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNL
Sbjct: 61 QFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNL 120
Query: 132 LKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIA 191
LKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIA
Sbjct: 121 LKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIA 180
Query: 192 DGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSP 251
DGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSP
Sbjct: 181 DGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSP 240
Query: 252 PSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNESTIEQIDKKL 311
PSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNESTIEQIDKKL
Sbjct: 241 PSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNESTIEQIDKKL 300
Query: 312 ERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQELSSDLNVGDT 371
ERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQELSSDLNVGDT
Sbjct: 301 ERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQELSSDLNVGDT 360
Query: 372 SQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDL 431
SQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDL
Sbjct: 361 SQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDL 420
Query: 432 SEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDE 491
SEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDE
Sbjct: 421 SEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDE 480
Query: 492 RNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTTHSGAEKDVDVS 551
RNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTTHSGAEKDVDVS
Sbjct: 481 RNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTTHSGAEKDVDVS 540
Query: 552 EDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSENEKCDHPAGG 611
EDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSENEKCDHPAGG
Sbjct: 541 EDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSENEKCDHPAGG 600
Query: 612 IHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT 661
IHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT
Sbjct: 601 IHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT 650
>gi|224586931 protein tyrosine phosphatase, non-receptor type 22
(lymphoid) isoform 2 [Homo sapiens]
Length = 691
Score = 275 bits (704), Expect = 7e-74
Identities = 206/599 (34%), Positives = 289/599 (48%), Gaps = 112/599 (18%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
MIWEY+V+IIVMAC E+EMG+KKCERYW GE + F PF +SCE E+ ++DY IRTL
Sbjct: 116 MIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLK 175
Query: 61 LEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTG 120
++F +E+R +YQFHY NWPDHDVPSS D IL++I +R YQE + VPICIHCSAGCGRTG
Sbjct: 176 VKFNSETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTG 235
Query: 121 AICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQ 180
ICAIDYTW LLK G IPE F+VF+LI+EMRTQR S VQT+EQYELV+ A+ +LF++Q+
Sbjct: 236 VICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMD 295
Query: 181 LYEIHGAQKIADGVNEINTENMVSSIEPEKQ-----DSPPPKPPRTRS----CLVEGDAK 231
+ I D TE+ PEK DS P P++ + + + K
Sbjct: 296 V--------IRD--KHSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTK 345
Query: 232 EEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYS 291
EI + S+F T+ + VLH S L NYS
Sbjct: 346 MEIKE---------------SSSFDFRTSEISAKEEL----VLHPAKSSTSFDFLELNYS 386
Query: 292 KSTELPGKNESTIEQIDKKLERNLSFEIKKVPLQEGP----KSFDGNTLLNRGHAIKIKS 347
DK + + ++ K P+ P +S D +LL G
Sbjct: 387 ---------------FDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSLLFEG------- 424
Query: 348 ASPCIADKISKPQELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRL 407
C SKP +N NS V + T+S TP E Q +T
Sbjct: 425 ---C---SNSKP------VNAAGRYFNSKVPITRTKS-----TPFELIQQRETK------ 461
Query: 408 PLDEKGHVTWSFHGPENA----IPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLV 463
+D K + ++ P ++ + + +S+++NY SL Q+ V
Sbjct: 462 EVDSKENFSYLESQPHDSCFVEMQAQKVMHVSSAELNY------SLPYDSKHQIRNASNV 515
Query: 464 DHDNTS--------PLFRTPLSFTNPLHSDDSDSD---ERNSDGAVTQNKTNISTASATV 512
H ++S PL P + P S DG V + +++++
Sbjct: 516 KHHDSSALGVYSYIPLVENPYFSSWPPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLF 575
Query: 513 SAATSTESISTRKVLPMSIARHNIAGTTHSGAEKDVDVSEDSPPPLPERTPESFVLASE 571
S S +S+S +S + + + + ++ PPPLP RTPESF++ E
Sbjct: 576 SYYNSHDSLSLNSPTNISSLLNQESAVLATAPR----IDDEIPPPLPVRTPESFIVVEE 630
>gi|224586929 protein tyrosine phosphatase, non-receptor type 22
(lymphoid) isoform 1 [Homo sapiens]
Length = 807
Score = 275 bits (704), Expect = 7e-74
Identities = 206/599 (34%), Positives = 289/599 (48%), Gaps = 112/599 (18%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
MIWEY+V+IIVMAC E+EMG+KKCERYW GE + F PF +SCE E+ ++DY IRTL
Sbjct: 116 MIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLK 175
Query: 61 LEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTG 120
++F +E+R +YQFHY NWPDHDVPSS D IL++I +R YQE + VPICIHCSAGCGRTG
Sbjct: 176 VKFNSETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTG 235
Query: 121 AICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQ 180
ICAIDYTW LLK G IPE F+VF+LI+EMRTQR S VQT+EQYELV+ A+ +LF++Q+
Sbjct: 236 VICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMD 295
Query: 181 LYEIHGAQKIADGVNEINTENMVSSIEPEKQ-----DSPPPKPPRTRS----CLVEGDAK 231
+ I D TE+ PEK DS P P++ + + + K
Sbjct: 296 V--------IRD--KHSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTK 345
Query: 232 EEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYS 291
EI + S+F T+ + VLH S L NYS
Sbjct: 346 MEIKE---------------SSSFDFRTSEISAKEEL----VLHPAKSSTSFDFLELNYS 386
Query: 292 KSTELPGKNESTIEQIDKKLERNLSFEIKKVPLQEGP----KSFDGNTLLNRGHAIKIKS 347
DK + + ++ K P+ P +S D +LL G
Sbjct: 387 ---------------FDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSLLFEG------- 424
Query: 348 ASPCIADKISKPQELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRL 407
C SKP +N NS V + T+S TP E Q +T
Sbjct: 425 ---C---SNSKP------VNAAGRYFNSKVPITRTKS-----TPFELIQQRETK------ 461
Query: 408 PLDEKGHVTWSFHGPENA----IPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLV 463
+D K + ++ P ++ + + +S+++NY SL Q+ V
Sbjct: 462 EVDSKENFSYLESQPHDSCFVEMQAQKVMHVSSAELNY------SLPYDSKHQIRNASNV 515
Query: 464 DHDNTS--------PLFRTPLSFTNPLHSDDSDSD---ERNSDGAVTQNKTNISTASATV 512
H ++S PL P + P S DG V + +++++
Sbjct: 516 KHHDSSALGVYSYIPLVENPYFSSWPPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLF 575
Query: 513 SAATSTESISTRKVLPMSIARHNIAGTTHSGAEKDVDVSEDSPPPLPERTPESFVLASE 571
S S +S+S +S + + + + ++ PPPLP RTPESF++ E
Sbjct: 576 SYYNSHDSLSLNSPTNISSLLNQESAVLATAPR----IDDEIPPPLPVRTPESFIVVEE 630
Score = 59.3 bits (142), Expect = 1e-08
Identities = 38/116 (32%), Positives = 53/116 (45%), Gaps = 14/116 (12%)
Query: 555 PPPLPERTPESFVLASE----------HNTPVRSEWSELQSQERSEQKKSEGLITSENEK 604
PPPLPERT ESF LA E ++T S +++ + + S++ K
Sbjct: 694 PPPLPERTLESFFLADEDCMQAQSIETYSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLK 753
Query: 605 CDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEW 660
+ +C CPP + Q S N + + GF NR KPKGPR+PP W
Sbjct: 754 I---LRNMKKSICNSCPPNKPAESVQ-SNNSSSFLNFGFANRFSKPKGPRNPPPTW 805
>gi|18375655 protein tyrosine phosphatase, non-receptor type 18
isoform 1 [Homo sapiens]
Length = 460
Score = 176 bits (445), Expect = 8e-44
Identities = 83/181 (45%), Positives = 119/181 (65%), Gaps = 2/181 (1%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQ-ARTDYFIRTL 59
++WE+ V +I+MACRE E GRK+CERYW ++P+ F I+ E+ D +RTL
Sbjct: 118 LVWEFGVKVILMACREIENGRKRCERYWA-QEQEPLQTGLFCITLIKEKWLNEDIMLRTL 176
Query: 60 LLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRT 119
+ FQ ESR +YQ Y++WPD VPSS D +L M+ R+ Q P+C+HCSAGCGRT
Sbjct: 177 KVTFQKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRT 236
Query: 120 GAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQL 179
G +C +DY LL IP +F++F+++ +MR QR +AVQT+EQY ++ +AQ+F L
Sbjct: 237 GVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMFCSTL 296
Query: 180 Q 180
Q
Sbjct: 297 Q 297
Score = 41.2 bits (95), Expect = 0.003
Identities = 15/21 (71%), Positives = 18/21 (85%)
Query: 641 IGFGNRCGKPKGPRDPPSEWT 661
+GF R G+PKGPRDPP+EWT
Sbjct: 438 LGFNLRIGRPKGPRDPPAEWT 458
>gi|215277017 protein tyrosine phosphatase, non-receptor type 18
isoform 2 [Homo sapiens]
Length = 353
Score = 146 bits (369), Expect = 5e-35
Identities = 71/160 (44%), Positives = 102/160 (63%), Gaps = 2/160 (1%)
Query: 22 KKCERYWPLYGEDPITFAPFKISCEDEQ-ARTDYFIRTLLLEFQNESRRLYQFHYVNWPD 80
K+CERYW ++P+ F I+ E+ D +RTL + FQ ESR +YQ Y++WPD
Sbjct: 32 KRCERYWA-QEQEPLQTGLFCITLIKEKWLNEDIMLRTLKVTFQKESRSVYQLQYMSWPD 90
Query: 81 HDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEE 140
VPSS D +L M+ R+ Q P+C+HCSAGCGRTG +C +DY LL IP +
Sbjct: 91 RGVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPD 150
Query: 141 FNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQ 180
F++F+++ +MR QR +AVQT+EQY ++ +AQ+F LQ
Sbjct: 151 FSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMFCSTLQ 190
Score = 41.2 bits (95), Expect = 0.003
Identities = 15/21 (71%), Positives = 18/21 (85%)
Query: 641 IGFGNRCGKPKGPRDPPSEWT 661
+GF R G+PKGPRDPP+EWT
Sbjct: 331 LGFNLRIGRPKGPRDPPAEWT 351
>gi|18104993 protein tyrosine phosphatase, non-receptor type 6
isoform 3 [Homo sapiens]
Length = 624
Score = 127 bits (318), Expect = 4e-29
Identities = 85/262 (32%), Positives = 124/262 (47%), Gaps = 22/262 (8%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
M W+ N +IVM RE E GR KC YWP G + P+ ++ E T+Y +RTL
Sbjct: 338 MAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQR-AYGPYSVTNCGEHDTTEYKLRTLQ 396
Query: 61 ---LEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEH--EDVPICIHCSAG 115
L+ + R ++ + Y++WPDH VPS +L + + + QE PI +HCSAG
Sbjct: 397 VSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAG 456
Query: 116 CGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLF 175
GRTG I ID + + + ++ IQ +R QR VQT+ QY+ ++ AIAQ
Sbjct: 457 IGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFI 516
Query: 176 EKQLQLYEIHGAQKIADGVNEINTENMVSSIE-PEKQDSPPPKPPRTRSCLVEGDAKEEI 234
E + E+ +QK E+ +I P + K RT S +E A
Sbjct: 517 ETTKKKLEVLQSQK--------GQESEYGNITYPPAMKNAHAKASRTSSKSLESSAGTVA 568
Query: 235 LQPPE-------PHPVPPILTP 249
P P P PP+L+P
Sbjct: 569 ASPVRRGGQRGLPVPGPPVLSP 590
>gi|148539860 protein tyrosine phosphatase, receptor type, T isoform 2
precursor [Homo sapiens]
Length = 1441
Score = 122 bits (305), Expect = 1e-27
Identities = 66/175 (37%), Positives = 96/175 (54%), Gaps = 8/175 (4%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
MIW+ N IVM E+GR KC RYWP +D + K++ + + +Y IRT
Sbjct: 974 MIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYGDIKVTLIETEPLAEYVIRTFT 1030
Query: 61 LEFQ--NESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGR 118
++ + +E R L FH+ +WPDH VP +L + ++ E PI +HCSAG GR
Sbjct: 1031 VQKKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGR 1090
Query: 119 TGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQ 173
TG AID +L + ++FN ++E+R QR + VQT+EQY VH AI +
Sbjct: 1091 TGCFIAID---TMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILE 1142
Score = 66.2 bits (160), Expect = 9e-11
Identities = 49/177 (27%), Positives = 84/177 (47%), Gaps = 17/177 (9%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWP-----LYGEDPITFAPFKISCEDEQARTDYF 55
++++YN +VM E + + C +YWP YG + F I DE F
Sbjct: 1263 LVFDYNCSSVVML-NEMDTAQF-CMQYWPEKTSGCYGPIQVEFVSADI---DEDIIHRIF 1317
Query: 56 IRTLLLEFQNESRRLYQFHYVNWPDH-DVPSSFDSILDMISLMRKYQEHEDVP---ICIH 111
+ Q+ R + Y+ WP + D P S S+L ++ + K+QE D +H
Sbjct: 1318 RICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVH 1377
Query: 112 CSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVH 168
C G GR+G CAI +++ I +VF++++ +R + + V+T EQY+ V+
Sbjct: 1378 CLNGGGRSGTFCAICSVCEMIQQQNI---IDVFHIVKTLRNNKSNMVETLEQYKFVY 1431
>gi|148539858 protein tyrosine phosphatase, receptor type, T isoform 1
precursor [Homo sapiens]
Length = 1460
Score = 122 bits (305), Expect = 1e-27
Identities = 66/175 (37%), Positives = 96/175 (54%), Gaps = 8/175 (4%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
MIW+ N IVM E+GR KC RYWP +D + K++ + + +Y IRT
Sbjct: 993 MIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYGDIKVTLIETEPLAEYVIRTFT 1049
Query: 61 LEFQ--NESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGR 118
++ + +E R L FH+ +WPDH VP +L + ++ E PI +HCSAG GR
Sbjct: 1050 VQKKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGR 1109
Query: 119 TGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQ 173
TG AID +L + ++FN ++E+R QR + VQT+EQY VH AI +
Sbjct: 1110 TGCFIAID---TMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILE 1161
Score = 66.2 bits (160), Expect = 9e-11
Identities = 49/177 (27%), Positives = 84/177 (47%), Gaps = 17/177 (9%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWP-----LYGEDPITFAPFKISCEDEQARTDYF 55
++++YN +VM E + + C +YWP YG + F I DE F
Sbjct: 1282 LVFDYNCSSVVML-NEMDTAQF-CMQYWPEKTSGCYGPIQVEFVSADI---DEDIIHRIF 1336
Query: 56 IRTLLLEFQNESRRLYQFHYVNWPDH-DVPSSFDSILDMISLMRKYQEHEDVP---ICIH 111
+ Q+ R + Y+ WP + D P S S+L ++ + K+QE D +H
Sbjct: 1337 RICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVH 1396
Query: 112 CSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVH 168
C G GR+G CAI +++ I +VF++++ +R + + V+T EQY+ V+
Sbjct: 1397 CLNGGGRSGTFCAICSVCEMIQQQNI---IDVFHIVKTLRNNKSNMVETLEQYKFVY 1450
>gi|208431815 protein tyrosine phosphatase, receptor type, K isoform a
[Homo sapiens]
Length = 1446
Score = 121 bits (304), Expect = 2e-27
Identities = 62/175 (35%), Positives = 96/175 (54%), Gaps = 8/175 (4%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
MIW+ IVM E+GR KC +YWP +D + FK++C + + +Y +RT
Sbjct: 979 MIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYGDFKVTCVEMEPLAEYVVRTFT 1035
Query: 61 LEFQ--NESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGR 118
LE + NE R + QFH+ WPDH VP +L I ++ PI +HCSAG GR
Sbjct: 1036 LERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPSAGPIVVHCSAGAGR 1095
Query: 119 TGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQ 173
TG ID ++ + + +++N ++ +R++R + VQT+EQY +H AI +
Sbjct: 1096 TGCYIVIDIMLDMAEREGV---VDIYNCVKALRSRRINMVQTEEQYIFIHDAILE 1147
Score = 67.0 bits (162), Expect = 5e-11
Identities = 49/184 (26%), Positives = 82/184 (44%), Gaps = 15/184 (8%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTL- 59
++++Y IVM E ++ + C +YWP E + + P ++ C D R
Sbjct: 1268 LVYDYGCTSIVML-NEVDLSQG-CPQYWP--EEGMLRYGPIQVECMSCSMDCDVINRIFR 1323
Query: 60 ---LLEFQNESRRLYQFHYVNWPDH-DVPSSFDSILDMISLMRKYQEH---EDVPICIHC 112
L Q + QF Y+ W H +VP S S L +I + K+QE + IHC
Sbjct: 1324 ICNLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHC 1383
Query: 113 SAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIA 172
G GR+G CAI ++K + +VF+ ++ +R + + V+ EQY +
Sbjct: 1384 LNGGGRSGMFCAIGIVVEMVKRQNV---VDVFHAVKTLRNSKPNMVEAPEQYRFCYDVAL 1440
Query: 173 QLFE 176
+ E
Sbjct: 1441 EYLE 1444
>gi|18860902 protein tyrosine phosphatase, receptor type, K isoform b
[Homo sapiens]
Length = 1440
Score = 121 bits (304), Expect = 2e-27
Identities = 62/175 (35%), Positives = 96/175 (54%), Gaps = 8/175 (4%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
MIW+ IVM E+GR KC +YWP +D + FK++C + + +Y +RT
Sbjct: 973 MIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYGDFKVTCVEMEPLAEYVVRTFT 1029
Query: 61 LEFQ--NESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGR 118
LE + NE R + QFH+ WPDH VP +L I ++ PI +HCSAG GR
Sbjct: 1030 LERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPSAGPIVVHCSAGAGR 1089
Query: 119 TGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQ 173
TG ID ++ + + +++N ++ +R++R + VQT+EQY +H AI +
Sbjct: 1090 TGCYIVIDIMLDMAEREGV---VDIYNCVKALRSRRINMVQTEEQYIFIHDAILE 1141
Score = 67.0 bits (162), Expect = 5e-11
Identities = 49/184 (26%), Positives = 82/184 (44%), Gaps = 15/184 (8%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTL- 59
++++Y IVM E ++ + C +YWP E + + P ++ C D R
Sbjct: 1262 LVYDYGCTSIVML-NEVDLSQG-CPQYWP--EEGMLRYGPIQVECMSCSMDCDVINRIFR 1317
Query: 60 ---LLEFQNESRRLYQFHYVNWPDH-DVPSSFDSILDMISLMRKYQEH---EDVPICIHC 112
L Q + QF Y+ W H +VP S S L +I + K+QE + IHC
Sbjct: 1318 ICNLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHC 1377
Query: 113 SAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIA 172
G GR+G CAI ++K + +VF+ ++ +R + + V+ EQY +
Sbjct: 1378 LNGGGRSGMFCAIGIVVEMVKRQNV---VDVFHAVKTLRNSKPNMVEAPEQYRFCYDVAL 1434
Query: 173 QLFE 176
+ E
Sbjct: 1435 EYLE 1438
>gi|18104989 protein tyrosine phosphatase, non-receptor type 6
isoform 1 [Homo sapiens]
Length = 595
Score = 121 bits (304), Expect = 2e-27
Identities = 69/194 (35%), Positives = 102/194 (52%), Gaps = 6/194 (3%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
M W+ N +IVM RE E GR KC YWP G + P+ ++ E T+Y +RTL
Sbjct: 338 MAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQR-AYGPYSVTNCGEHDTTEYKLRTLQ 396
Query: 61 ---LEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEH--EDVPICIHCSAG 115
L+ + R ++ + Y++WPDH VPS +L + + + QE PI +HCSAG
Sbjct: 397 VSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAG 456
Query: 116 CGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLF 175
GRTG I ID + + + ++ IQ +R QR VQT+ QY+ ++ AIAQ
Sbjct: 457 IGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFI 516
Query: 176 EKQLQLYEIHGAQK 189
E + E+ +QK
Sbjct: 517 ETTKKKLEVLQSQK 530
>gi|18104991 protein tyrosine phosphatase, non-receptor type 6
isoform 2 [Homo sapiens]
Length = 597
Score = 121 bits (304), Expect = 2e-27
Identities = 69/194 (35%), Positives = 102/194 (52%), Gaps = 6/194 (3%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
M W+ N +IVM RE E GR KC YWP G + P+ ++ E T+Y +RTL
Sbjct: 340 MAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQR-AYGPYSVTNCGEHDTTEYKLRTLQ 398
Query: 61 ---LEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEH--EDVPICIHCSAG 115
L+ + R ++ + Y++WPDH VPS +L + + + QE PI +HCSAG
Sbjct: 399 VSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAG 458
Query: 116 CGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLF 175
GRTG I ID + + + ++ IQ +R QR VQT+ QY+ ++ AIAQ
Sbjct: 459 IGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFI 518
Query: 176 EKQLQLYEIHGAQK 189
E + E+ +QK
Sbjct: 519 ETTKKKLEVLQSQK 532
>gi|4506301 protein tyrosine phosphatase, non-receptor type 9 [Homo
sapiens]
Length = 593
Score = 117 bits (293), Expect = 3e-26
Identities = 67/194 (34%), Positives = 104/194 (53%), Gaps = 20/194 (10%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
M+WE V++IVM R E GR+KC +YWPL + I F ++ + Y TL
Sbjct: 389 MVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLE 448
Query: 61 LE--FQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQ-------------EHED 105
+ + + R++ F +++WPD+ VPSS S++D + ++R Q + +
Sbjct: 449 IHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSLAVSNMGARSKGQCPE 508
Query: 106 VPICIHCSAGCGRTGAICAIDYTW-NLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQY 164
PI +HCSAG GRTG C++D L + G + NVF + MRTQR ++QT EQY
Sbjct: 509 PPIVVHCSAGIGRTGTFCSLDICLAQLEELGTL----NVFQTVSRMRTQRAFSIQTPEQY 564
Query: 165 ELVHRAIAQLFEKQ 178
++AI + EK+
Sbjct: 565 YFCYKAILEFAEKE 578
>gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Homo
sapiens]
Length = 926
Score = 116 bits (291), Expect = 6e-26
Identities = 60/182 (32%), Positives = 97/182 (53%), Gaps = 12/182 (6%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPI---TFAPFKISCEDEQARTDYFIR 57
M WE ++VM + E GR KC +YWP +P ++ ++++C E+ T Y R
Sbjct: 740 MTWEQGSSMVVMLTTQVERGRVKCHQYWP----EPTGSSSYGCYQVTCHSEEGNTAYIFR 795
Query: 58 --TLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAG 115
TL + +NESR L Q Y+ WPDH VP LD + +R + ++ P+ +HCSAG
Sbjct: 796 KMTLFNQEKNESRPLTQIQYIAWPDHGVPDDSSDFLDFVCHVRNKRAGKEEPVVVHCSAG 855
Query: 116 CGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLF 175
GRTG + ++ L++ + ++++ MR QR +QT QY V AI +++
Sbjct: 856 IGRTGVLITMETAMCLIECN---QPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVY 912
Query: 176 EK 177
E+
Sbjct: 913 EE 914
>gi|13677222 receptor-type protein tyrosine phosphatase O isoform c
precursor [Homo sapiens]
Length = 405
Score = 115 bits (288), Expect = 1e-25
Identities = 62/184 (33%), Positives = 102/184 (55%), Gaps = 6/184 (3%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
M+ + IIVM + E R KC+ YWP + E+PI + + E+ + D+ R
Sbjct: 213 MVLQQKSQIIVMLTQCNEKRRVKCDHYWP-FTEEPIAYGDITVEMISEEEQDDWACRHFR 271
Query: 61 LEFQNESRRLYQFHYVNWPDHDVP--SSFDSILDMISLMRKYQEHEDVPICIHCSAGCGR 118
+ + +E + + F+Y WPDH VP ++ +SIL + ++R+ P+ IHCSAG GR
Sbjct: 272 INYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGR 331
Query: 119 TGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQ 178
TG A+D LL+ + E ++ L+ EMR+ R S VQT+EQY +H+ + ++ K+
Sbjct: 332 TGTFIALD---RLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKK 388
Query: 179 LQLY 182
Q +
Sbjct: 389 KQQF 392
>gi|13677220 receptor-type protein tyrosine phosphatase O isoform d
precursor [Homo sapiens]
Length = 377
Score = 115 bits (288), Expect = 1e-25
Identities = 62/184 (33%), Positives = 102/184 (55%), Gaps = 6/184 (3%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
M+ + IIVM + E R KC+ YWP + E+PI + + E+ + D+ R
Sbjct: 185 MVLQQKSQIIVMLTQCNEKRRVKCDHYWP-FTEEPIAYGDITVEMISEEEQDDWACRHFR 243
Query: 61 LEFQNESRRLYQFHYVNWPDHDVP--SSFDSILDMISLMRKYQEHEDVPICIHCSAGCGR 118
+ + +E + + F+Y WPDH VP ++ +SIL + ++R+ P+ IHCSAG GR
Sbjct: 244 INYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGR 303
Query: 119 TGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQ 178
TG A+D LL+ + E ++ L+ EMR+ R S VQT+EQY +H+ + ++ K+
Sbjct: 304 TGTFIALD---RLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKK 360
Query: 179 LQLY 182
Q +
Sbjct: 361 KQQF 364
>gi|13677218 receptor-type protein tyrosine phosphatase O isoform c
precursor [Homo sapiens]
Length = 405
Score = 115 bits (288), Expect = 1e-25
Identities = 62/184 (33%), Positives = 102/184 (55%), Gaps = 6/184 (3%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
M+ + IIVM + E R KC+ YWP + E+PI + + E+ + D+ R
Sbjct: 213 MVLQQKSQIIVMLTQCNEKRRVKCDHYWP-FTEEPIAYGDITVEMISEEEQDDWACRHFR 271
Query: 61 LEFQNESRRLYQFHYVNWPDHDVP--SSFDSILDMISLMRKYQEHEDVPICIHCSAGCGR 118
+ + +E + + F+Y WPDH VP ++ +SIL + ++R+ P+ IHCSAG GR
Sbjct: 272 INYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGR 331
Query: 119 TGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQ 178
TG A+D LL+ + E ++ L+ EMR+ R S VQT+EQY +H+ + ++ K+
Sbjct: 332 TGTFIALD---RLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKK 388
Query: 179 LQLY 182
Q +
Sbjct: 389 KQQF 392
>gi|13677216 receptor-type protein tyrosine phosphatase O isoform d
precursor [Homo sapiens]
Length = 377
Score = 115 bits (288), Expect = 1e-25
Identities = 62/184 (33%), Positives = 102/184 (55%), Gaps = 6/184 (3%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
M+ + IIVM + E R KC+ YWP + E+PI + + E+ + D+ R
Sbjct: 185 MVLQQKSQIIVMLTQCNEKRRVKCDHYWP-FTEEPIAYGDITVEMISEEEQDDWACRHFR 243
Query: 61 LEFQNESRRLYQFHYVNWPDHDVP--SSFDSILDMISLMRKYQEHEDVPICIHCSAGCGR 118
+ + +E + + F+Y WPDH VP ++ +SIL + ++R+ P+ IHCSAG GR
Sbjct: 244 INYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGR 303
Query: 119 TGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQ 178
TG A+D LL+ + E ++ L+ EMR+ R S VQT+EQY +H+ + ++ K+
Sbjct: 304 TGTFIALD---RLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKK 360
Query: 179 LQLY 182
Q +
Sbjct: 361 KQQF 364
>gi|13677214 receptor-type protein tyrosine phosphatase O isoform a
precursor [Homo sapiens]
Length = 1216
Score = 115 bits (288), Expect = 1e-25
Identities = 62/184 (33%), Positives = 102/184 (55%), Gaps = 6/184 (3%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
M+ + IIVM + E R KC+ YWP + E+PI + + E+ + D+ R
Sbjct: 1024 MVLQQKSQIIVMLTQCNEKRRVKCDHYWP-FTEEPIAYGDITVEMISEEEQDDWACRHFR 1082
Query: 61 LEFQNESRRLYQFHYVNWPDHDVP--SSFDSILDMISLMRKYQEHEDVPICIHCSAGCGR 118
+ + +E + + F+Y WPDH VP ++ +SIL + ++R+ P+ IHCSAG GR
Sbjct: 1083 INYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGR 1142
Query: 119 TGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQ 178
TG A+D LL+ + E ++ L+ EMR+ R S VQT+EQY +H+ + ++ K+
Sbjct: 1143 TGTFIALD---RLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKK 1199
Query: 179 LQLY 182
Q +
Sbjct: 1200 KQQF 1203
>gi|4506323 receptor-type protein tyrosine phosphatase O isoform b
precursor [Homo sapiens]
Length = 1188
Score = 115 bits (288), Expect = 1e-25
Identities = 62/184 (33%), Positives = 102/184 (55%), Gaps = 6/184 (3%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
M+ + IIVM + E R KC+ YWP + E+PI + + E+ + D+ R
Sbjct: 996 MVLQQKSQIIVMLTQCNEKRRVKCDHYWP-FTEEPIAYGDITVEMISEEEQDDWACRHFR 1054
Query: 61 LEFQNESRRLYQFHYVNWPDHDVP--SSFDSILDMISLMRKYQEHEDVPICIHCSAGCGR 118
+ + +E + + F+Y WPDH VP ++ +SIL + ++R+ P+ IHCSAG GR
Sbjct: 1055 INYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGR 1114
Query: 119 TGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQ 178
TG A+D LL+ + E ++ L+ EMR+ R S VQT+EQY +H+ + ++ K+
Sbjct: 1115 TGTFIALD---RLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKK 1171
Query: 179 LQLY 182
Q +
Sbjct: 1172 KQQF 1175
>gi|157419150 protein tyrosine phosphatase, receptor type, M isoform 2
precursor [Homo sapiens]
Length = 1452
Score = 115 bits (287), Expect = 2e-25
Identities = 57/175 (32%), Positives = 95/175 (54%), Gaps = 8/175 (4%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
M+W N I+M E+GR KC +YWP +D + K++ + + +Y IRT
Sbjct: 985 MVWHENTASIIMVTNLVEVGRVKCCKYWP---DDTEIYKDIKVTLIETELLAEYVIRTFA 1041
Query: 61 LEFQ--NESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGR 118
+E + +E R + QFH+ WPDH VP +L + ++ P+ +HCSAG GR
Sbjct: 1042 VEKRGVHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPSAGPLVVHCSAGAGR 1101
Query: 119 TGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQ 173
TG ID ++ + + +++N ++E+R++R + VQT+EQY +H AI +
Sbjct: 1102 TGCFIVIDIMLDMAEREGV---VDIYNCVRELRSRRVNMVQTEEQYVFIHDAILE 1153
Score = 54.3 bits (129), Expect = 4e-07
Identities = 39/153 (25%), Positives = 67/153 (43%), Gaps = 13/153 (8%)
Query: 24 CERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL----EFQNESRRLYQFHYVNWP 79
C +YWP G P ++ D R + Q+ R + QF ++ WP
Sbjct: 1295 CPQYWPENGVH--RHGPIQVEFVSADLEEDIISRIFRIYNAARPQDGYRMVQQFQFLGWP 1352
Query: 80 DH-DVPSSFDSILDMISLMRKYQEHE---DVPICIHCSAGCGRTGAICAIDYTWNLLKAG 135
+ D P S S L +I + K+QE + +HC G GR+G CAI +L+
Sbjct: 1353 MYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRTVVHCLNGGGRSGTFCAISIVCEMLRHQ 1412
Query: 136 KIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVH 168
+ +VF+ ++ +R + + V +QY+ +
Sbjct: 1413 R---TVDVFHAVKTLRNNKPNMVDLLDQYKFCY 1442
>gi|157419152 protein tyrosine phosphatase, receptor type, M isoform 1
precursor [Homo sapiens]
Length = 1465
Score = 115 bits (287), Expect = 2e-25
Identities = 57/175 (32%), Positives = 95/175 (54%), Gaps = 8/175 (4%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
M+W N I+M E+GR KC +YWP +D + K++ + + +Y IRT
Sbjct: 998 MVWHENTASIIMVTNLVEVGRVKCCKYWP---DDTEIYKDIKVTLIETELLAEYVIRTFA 1054
Query: 61 LEFQ--NESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGR 118
+E + +E R + QFH+ WPDH VP +L + ++ P+ +HCSAG GR
Sbjct: 1055 VEKRGVHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPSAGPLVVHCSAGAGR 1114
Query: 119 TGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQ 173
TG ID ++ + + +++N ++E+R++R + VQT+EQY +H AI +
Sbjct: 1115 TGCFIVIDIMLDMAEREGV---VDIYNCVRELRSRRVNMVQTEEQYVFIHDAILE 1166
Score = 54.3 bits (129), Expect = 4e-07
Identities = 39/153 (25%), Positives = 67/153 (43%), Gaps = 13/153 (8%)
Query: 24 CERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL----EFQNESRRLYQFHYVNWP 79
C +YWP G P ++ D R + Q+ R + QF ++ WP
Sbjct: 1308 CPQYWPENGVH--RHGPIQVEFVSADLEEDIISRIFRIYNAARPQDGYRMVQQFQFLGWP 1365
Query: 80 DH-DVPSSFDSILDMISLMRKYQEHE---DVPICIHCSAGCGRTGAICAIDYTWNLLKAG 135
+ D P S S L +I + K+QE + +HC G GR+G CAI +L+
Sbjct: 1366 MYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRTVVHCLNGGGRSGTFCAISIVCEMLRHQ 1425
Query: 136 KIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVH 168
+ +VF+ ++ +R + + V +QY+ +
Sbjct: 1426 R---TVDVFHAVKTLRNNKPNMVDLLDQYKFCY 1455
>gi|18450371 protein tyrosine phosphatase, receptor type, A isoform
2 precursor [Homo sapiens]
Length = 793
Score = 114 bits (286), Expect = 2e-25
Identities = 61/179 (34%), Positives = 100/179 (55%), Gaps = 8/179 (4%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
MIWE+ IVM E G++KC +YWP G +++ + + E+ Y +R LL
Sbjct: 611 MIWEWKSCSIVMLTELEERGQEKCAQYWPSDGL--VSYGDITVELKKEEECESYTVRDLL 668
Query: 61 LEF--QNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHE-DVPICIHCSAGCG 117
+ +N+SR++ QFH+ WP+ +PS ++ +I+ ++K Q+ + PI +HCSAG G
Sbjct: 669 VTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAG 728
Query: 118 RTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFE 176
RTG CA+ +KA I +VF ++ +R QR VQT EQYE ++ + + +
Sbjct: 729 RTGTFCALSTVLERVKAEGI---LDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID 784
Score = 93.6 bits (231), Expect = 5e-19
Identities = 54/179 (30%), Positives = 85/179 (47%), Gaps = 11/179 (6%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
MIWE N IVM E KC +YWP G T+ ++S ED DY +R
Sbjct: 318 MIWEQNTATIVMVTNLKERKECKCAQYWPDQG--CWTYGNIRVSVEDVTVLVDYTVRKFC 375
Query: 61 LEFQNE------SRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSA 114
++ + R + QFH+ +WPD VP + +L + ++ I +HCSA
Sbjct: 376 IQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSA 435
Query: 115 GCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQ 173
G GRTG ID +++ + + +V+ + +R QR VQT QY +++A+ +
Sbjct: 436 GVGRTGTFVVIDAMLDMMHTER---KVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE 491
>gi|4506303 protein tyrosine phosphatase, receptor type, A isoform 1
precursor [Homo sapiens]
Length = 802
Score = 114 bits (286), Expect = 2e-25
Identities = 61/179 (34%), Positives = 100/179 (55%), Gaps = 8/179 (4%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
MIWE+ IVM E G++KC +YWP G +++ + + E+ Y +R LL
Sbjct: 620 MIWEWKSCSIVMLTELEERGQEKCAQYWPSDGL--VSYGDITVELKKEEECESYTVRDLL 677
Query: 61 LEF--QNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHE-DVPICIHCSAGCG 117
+ +N+SR++ QFH+ WP+ +PS ++ +I+ ++K Q+ + PI +HCSAG G
Sbjct: 678 VTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAG 737
Query: 118 RTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFE 176
RTG CA+ +KA I +VF ++ +R QR VQT EQYE ++ + + +
Sbjct: 738 RTGTFCALSTVLERVKAEGI---LDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID 793
Score = 93.6 bits (231), Expect = 5e-19
Identities = 54/179 (30%), Positives = 85/179 (47%), Gaps = 11/179 (6%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
MIWE N IVM E KC +YWP G T+ ++S ED DY +R
Sbjct: 327 MIWEQNTATIVMVTNLKERKECKCAQYWPDQG--CWTYGNIRVSVEDVTVLVDYTVRKFC 384
Query: 61 LEFQNE------SRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSA 114
++ + R + QFH+ +WPD VP + +L + ++ I +HCSA
Sbjct: 385 IQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSA 444
Query: 115 GCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQ 173
G GRTG ID +++ + + +V+ + +R QR VQT QY +++A+ +
Sbjct: 445 GVGRTGTFVVIDAMLDMMHTER---KVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE 500
>gi|18450369 protein tyrosine phosphatase, receptor type, A isoform
2 precursor [Homo sapiens]
Length = 793
Score = 114 bits (286), Expect = 2e-25
Identities = 61/179 (34%), Positives = 100/179 (55%), Gaps = 8/179 (4%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
MIWE+ IVM E G++KC +YWP G +++ + + E+ Y +R LL
Sbjct: 611 MIWEWKSCSIVMLTELEERGQEKCAQYWPSDGL--VSYGDITVELKKEEECESYTVRDLL 668
Query: 61 LEF--QNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHE-DVPICIHCSAGCG 117
+ +N+SR++ QFH+ WP+ +PS ++ +I+ ++K Q+ + PI +HCSAG G
Sbjct: 669 VTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAG 728
Query: 118 RTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFE 176
RTG CA+ +KA I +VF ++ +R QR VQT EQYE ++ + + +
Sbjct: 729 RTGTFCALSTVLERVKAEGI---LDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID 784
Score = 93.6 bits (231), Expect = 5e-19
Identities = 54/179 (30%), Positives = 85/179 (47%), Gaps = 11/179 (6%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
MIWE N IVM E KC +YWP G T+ ++S ED DY +R
Sbjct: 318 MIWEQNTATIVMVTNLKERKECKCAQYWPDQG--CWTYGNIRVSVEDVTVLVDYTVRKFC 375
Query: 61 LEFQNE------SRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSA 114
++ + R + QFH+ +WPD VP + +L + ++ I +HCSA
Sbjct: 376 IQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSA 435
Query: 115 GCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQ 173
G GRTG ID +++ + + +V+ + +R QR VQT QY +++A+ +
Sbjct: 436 GVGRTGTFVVIDAMLDMMHTER---KVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE 491
>gi|241896926 protein tyrosine phosphatase, receptor type, H isoform
2 precursor [Homo sapiens]
Length = 937
Score = 114 bits (285), Expect = 3e-25
Identities = 65/184 (35%), Positives = 99/184 (53%), Gaps = 8/184 (4%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
++WE +VM E GR KCE YWPL + P T +++ E+ ++ +R LL
Sbjct: 728 LVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDSQ-PCTHGHLRVTLVGEEVMENWTVRELL 786
Query: 61 LEFQNESRRLY--QFHYVNWPDHDVPSSFDSILDMISLMRKY--QEHEDVPICIHCSAGC 116
L E + L QFHY WPDH VPSS D++L ++R++ Q E P +HCSAG
Sbjct: 787 LLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTMEGGPPIVHCSAGV 846
Query: 117 GRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFE 176
GRTG + A+D L++ + F+ +++MR R VQT+ QY +H+ I + +
Sbjct: 847 GRTGTLIALDVLLRQLQSEGL---LGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFLQ 903
Query: 177 KQLQ 180
+ Q
Sbjct: 904 QSAQ 907
>gi|241896924 protein tyrosine phosphatase, receptor type, H isoform 1
precursor [Homo sapiens]
Length = 1115
Score = 114 bits (285), Expect = 3e-25
Identities = 65/184 (35%), Positives = 99/184 (53%), Gaps = 8/184 (4%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
++WE +VM E GR KCE YWPL + P T +++ E+ ++ +R LL
Sbjct: 906 LVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDSQ-PCTHGHLRVTLVGEEVMENWTVRELL 964
Query: 61 LEFQNESRRLY--QFHYVNWPDHDVPSSFDSILDMISLMRKY--QEHEDVPICIHCSAGC 116
L E + L QFHY WPDH VPSS D++L ++R++ Q E P +HCSAG
Sbjct: 965 LLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTMEGGPPIVHCSAGV 1024
Query: 117 GRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFE 176
GRTG + A+D L++ + F+ +++MR R VQT+ QY +H+ I + +
Sbjct: 1025 GRTGTLIALDVLLRQLQSEGL---LGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFLQ 1081
Query: 177 KQLQ 180
+ Q
Sbjct: 1082 QSAQ 1085
>gi|148728162 protein tyrosine phosphatase, receptor type, J isoform 1
precursor [Homo sapiens]
Length = 1337
Score = 110 bits (274), Expect = 5e-24
Identities = 60/182 (32%), Positives = 96/182 (52%), Gaps = 9/182 (4%)
Query: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
M+WE NV I+M + E GR KCE YWP + + ++ E ++ IR
Sbjct: 1126 MVWEKNVYAIIMLTKCVEQGRTKCEEYWP--SKQAQDYGDITVAMTSEIVLPEWTIRDFT 1183
Query: 61 LE--FQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKY--QEHEDVPICIHCSAGC 116
++ +ES L QFH+ +WPDH VP + D +++ L+R Y Q + PI +HCSAG
Sbjct: 1184 VKNIQTSESHPLRQFHFTSWPDHGVPDTTDLLINFRYLVRDYMKQSPPESPILVHCSAGV 1243
Query: 117 GRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFE 176
GRTG AID L+ + +V+ ++ ++R R VQT++QY +++ + +
Sbjct: 1244 GRTGTFIAID---RLIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIVR 1300
Query: 177 KQ 178
Q
Sbjct: 1301 SQ 1302
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,708,851
Number of Sequences: 37866
Number of extensions: 1673846
Number of successful extensions: 9162
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 131
Number of HSP's successfully gapped in prelim test: 333
Number of HSP's that attempted gapping in prelim test: 7385
Number of HSP's gapped (non-prelim): 1596
length of query: 661
length of database: 18,247,518
effective HSP length: 109
effective length of query: 552
effective length of database: 14,120,124
effective search space: 7794308448
effective search space used: 7794308448
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.