Guide to the Human Genome
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Search of human proteins with 195947391

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|195947391 RAD51 associated protein 1 isoform a [Homo
sapiens]
         (352 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|195947391 RAD51 associated protein 1 isoform a [Homo sapiens]      690   0.0  
gi|5453904 RAD51 associated protein 1 isoform b [Homo sapiens]        644   0.0  
gi|56118310 nuclear casein kinase and cyclin-dependent kinase su...    69   6e-12
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     51   1e-06
gi|104526627 triadin [Homo sapiens]                                    51   2e-06
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo...    50   4e-06
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo...    50   4e-06
gi|5453567 craniofacial development protein 1 [Homo sapiens]           50   4e-06
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           44   2e-04
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]           44   2e-04
gi|156104891 general transcription factor IIF, polypeptide 1, 74...    43   4e-04
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo...    43   4e-04
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    43   5e-04
gi|4507241 structure specific recognition protein 1 [Homo sapiens]     42   6e-04
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]             42   0.001
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]             42   0.001
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    41   0.001
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor...    41   0.001
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          41   0.001
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H...    40   0.002
gi|217330641 IWS1 homolog [Homo sapiens]                               40   0.002
gi|48255931 hepatoma-derived growth factor-related protein 2 iso...    40   0.002
gi|14249158 hepatoma-derived growth factor-related protein 2 iso...    40   0.002
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              40   0.002
gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]    40   0.003
gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens]    40   0.003
gi|157266334 tubby like protein 1 [Homo sapiens]                       40   0.003
gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens]    40   0.004
gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens]     40   0.004
gi|55956788 nucleolin [Homo sapiens]                                   39   0.005

>gi|195947391 RAD51 associated protein 1 isoform a [Homo sapiens]
          Length = 352

 Score =  690 bits (1780), Expect = 0.0
 Identities = 352/352 (100%), Positives = 352/352 (100%)

Query: 1   MVRPVRHKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEI 60
           MVRPVRHKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEI
Sbjct: 1   MVRPVRHKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEI 60

Query: 61  PVQEKTPKKRLPEGTFSIPASAVPCTKMALDDKLYQRDLEVALALSVKELPTVTTNVQNS 120
           PVQEKTPKKRLPEGTFSIPASAVPCTKMALDDKLYQRDLEVALALSVKELPTVTTNVQNS
Sbjct: 61  PVQEKTPKKRLPEGTFSIPASAVPCTKMALDDKLYQRDLEVALALSVKELPTVTTNVQNS 120

Query: 121 QDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQ 180
           QDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQ
Sbjct: 121 QDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQ 180

Query: 181 RKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVK 240
           RKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVK
Sbjct: 181 RKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVK 240

Query: 241 SPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESK 300
           SPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESK
Sbjct: 241 SPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESK 300

Query: 301 KPKWVPPAASGGSRSSSSPLVVVSVKSPNQSLRLGLSRLARVKPLHPNATST 352
           KPKWVPPAASGGSRSSSSPLVVVSVKSPNQSLRLGLSRLARVKPLHPNATST
Sbjct: 301 KPKWVPPAASGGSRSSSSPLVVVSVKSPNQSLRLGLSRLARVKPLHPNATST 352


>gi|5453904 RAD51 associated protein 1 isoform b [Homo sapiens]
          Length = 335

 Score =  644 bits (1662), Expect = 0.0
 Identities = 335/352 (95%), Positives = 335/352 (95%), Gaps = 17/352 (4%)

Query: 1   MVRPVRHKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEI 60
           MVRPVRHKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEI
Sbjct: 1   MVRPVRHKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEI 60

Query: 61  PVQEKTPKKRLPEGTFSIPASAVPCTKMALDDKLYQRDLEVALALSVKELPTVTTNVQNS 120
           PVQEKTPKKR                 MALDDKLYQRDLEVALALSVKELPTVTTNVQNS
Sbjct: 61  PVQEKTPKKR-----------------MALDDKLYQRDLEVALALSVKELPTVTTNVQNS 103

Query: 121 QDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQ 180
           QDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQ
Sbjct: 104 QDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQ 163

Query: 181 RKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVK 240
           RKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVK
Sbjct: 164 RKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVK 223

Query: 241 SPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESK 300
           SPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESK
Sbjct: 224 SPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESK 283

Query: 301 KPKWVPPAASGGSRSSSSPLVVVSVKSPNQSLRLGLSRLARVKPLHPNATST 352
           KPKWVPPAASGGSRSSSSPLVVVSVKSPNQSLRLGLSRLARVKPLHPNATST
Sbjct: 284 KPKWVPPAASGGSRSSSSPLVVVSVKSPNQSLRLGLSRLARVKPLHPNATST 335


>gi|56118310 nuclear casein kinase and cyclin-dependent kinase
           substrate 1 [Homo sapiens]
          Length = 243

 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 63/216 (29%), Positives = 94/216 (43%), Gaps = 26/216 (12%)

Query: 106 SVKELPTVTTNVQNSQDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGG 165
           S +E      + +NSQ+ S E      ++T     H +           D    ++D   
Sbjct: 40  SPREAKNKRRSGKNSQEDS-EDSEDKDVKTKKDDSHSAE----------DSEDEKEDHKN 88

Query: 166 VQGKRKAASKAAAQQRKILLE--GSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFS 223
           V+ +R+AASKAA++QR++L+E  GS+ +   + E  F   +DS  D DF   +D+D D+ 
Sbjct: 89  VRQQRQAASKAASKQREMLMEDVGSEEEQEEEDEAPFQE-KDSGSDEDFLMEDDDDSDYG 147

Query: 224 MRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQ-SLPKKVSLS 282
             K K     KK VK   P  K++K  K +  A VT     P+ VK + +   P     S
Sbjct: 148 SSKKK----NKKMVKKSKPERKEKKMPKPRLKATVT-----PSPVKGKGKVGRPTASKAS 198

Query: 283 SDTTRKPLE--IRSPSAESKKPKWVPPAASGGSRSS 316
            + T  P E      S   KK    PP    G   S
Sbjct: 199 KEKTPSPKEEDEEPESPPEKKTSTSPPPEKSGDEGS 234


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 62/261 (23%), Positives = 114/261 (43%), Gaps = 50/261 (19%)

Query: 87  KMALDDKL--YQRDLE------------VALALSVKELPTVTTNVQNSQDKSIEKHGSSK 132
           KMALD ++  Y++ LE             +L   + ++P+V+T+++   ++ I+    S+
Sbjct: 392 KMALDIEIAAYRKLLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSE 451

Query: 133 IETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDS 192
            ET+          V       +++T E++            K A ++     EG + + 
Sbjct: 452 KETVIVEEQTEETQVT------EEVTEEEE------------KEAKEE-----EGKEEEG 488

Query: 193 ANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKS 252
             + E      E  E+++    +E+        KS VKE  K   + KSP EK+E KS +
Sbjct: 489 GEEEE-----AEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSP-EKEEAKSPA 542

Query: 253 KCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSP--SAESKKPKWVPPAAS 310
           +    V S + A +  K E++S P+  S   +  + P E++SP  +    K +   PA +
Sbjct: 543 E----VKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEA 598

Query: 311 GGSRSSSSPLVVVSVKSPNQS 331
                + SP V    KSP ++
Sbjct: 599 KSPEKAKSP-VKEEAKSPAEA 618



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 36/109 (33%), Positives = 55/109 (50%), Gaps = 7/109 (6%)

Query: 226 KSKVKEIKKKEVKVKSPVEKKEK---KSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLS 282
           KS VKE  K   K KSPV+++ K   K+KS       + + A + VK E++S P+K    
Sbjct: 695 KSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKS-PEKA--K 751

Query: 283 SDTTRKPLEIRSPSAESKKPKWVPPAASGGSRSSSSPLVVVSVKSPNQS 331
           S    K L+++SP A++   +     A      + SP V   VKSP ++
Sbjct: 752 SPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSP-VKEEVKSPEKA 799



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 5/134 (3%)

Query: 173 ASKAAAQQRKILLEGSDGDSANDTEPDFA--PGEDSEDDSDFCESEDNDEDFSMRKSKVK 230
           A   A ++ K   E    + A     + A  P E      +  +S    +     KS  K
Sbjct: 584 AKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTK 643

Query: 231 EIKKKEVKVKSPVEKKEK---KSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTR 287
           E  K   K KSP +++ K   K+KS   A   S + A + VK+E++S  K  S   +  +
Sbjct: 644 EEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK 703

Query: 288 KPLEIRSPSAESKK 301
            P + +SP  E  K
Sbjct: 704 SPEKAKSPVKEEAK 717



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 16/149 (10%)

Query: 198 PDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVK---EIKKKEVKVKSPVEKKEK------ 248
           P  A   + E+     E +  ++  S  K + K   E K  E K KSPV+++ K      
Sbjct: 561 PPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPE-KAKSPVKEEAKSPAEAK 619

Query: 249 ---KSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSP-SAESKKPKW 304
              K ++K  A V S + A +  K E++S  K  S   +  + P + +SP  AE+K P+ 
Sbjct: 620 SPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEK 679

Query: 305 V--PPAASGGSRSSSSPLVVVSVKSPNQS 331
              P  A   S   +   V    KSP ++
Sbjct: 680 AKSPVKAEAKSPEKAKSPVKEEAKSPEKA 708



 Score = 35.8 bits (81), Expect = 0.059
 Identities = 56/249 (22%), Positives = 93/249 (37%), Gaps = 52/249 (20%)

Query: 34  KKSRTAPKELKQDKPKPNLNNLRKEEI--PVQEKTPKKRL-----PEGTFSIPASAVPCT 86
           K    A   LK+D   P     +KEE+  PV+E+   + +     P+      A A P T
Sbjct: 794 KSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKT 853

Query: 87  KMALDDKLYQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETMNKSPHISNCS 146
           +   D K  +           KE P     V+  ++ ++EK   SK+E   +        
Sbjct: 854 EEKKDSKKEEAPK--------KEAPK--PKVEEKKEPAVEKPKESKVEAKKEEAEDKKKV 903

Query: 147 VASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDS 206
              +     K+ V++D      K K  ++ A +                 EPD A  ++ 
Sbjct: 904 PTPEKEAPAKVEVKEDA-----KPKEKTEVAKK-----------------EPDDAKAKEP 941

Query: 207 EDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVD-SAP 265
              ++  E+    +D             KE K K P EK + ++K+K +    S + S P
Sbjct: 942 SKPAEKKEAAPEKKD------------TKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKP 989

Query: 266 AAVKSESQS 274
            A K+E  S
Sbjct: 990 KAEKAEKSS 998



 Score = 35.8 bits (81), Expect = 0.059
 Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 5/80 (6%)

Query: 226 KSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDS--APAAVKSESQSLPKKVSLSS 283
           K+  KEI KKE +VKSPV+++EK  + K        +   APA  K+E +   KK     
Sbjct: 808 KAPEKEIPKKE-EVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPK 866

Query: 284 DTTRKPL--EIRSPSAESKK 301
               KP   E + P+ E  K
Sbjct: 867 KEAPKPKVEEKKEPAVEKPK 886



 Score = 33.1 bits (74), Expect = 0.38
 Identities = 64/322 (19%), Positives = 117/322 (36%), Gaps = 25/322 (7%)

Query: 4   PVRHKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEIPVQ 63
           P + K PV  ++    +     V A     +K+++  KE  +   K       + + P +
Sbjct: 663 PEKAKSPVK-AEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEK 721

Query: 64  EKTPKKRLPEGTFSIPASAVPCTKMALDDKLYQRDLEVALALSVKELPTVTTNVQNSQ-- 121
            K+P K   +     P  A    K         +  E A  L VK     T   + ++  
Sbjct: 722 AKSPVKEEAK----TPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSP 777

Query: 122 -DKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQ 180
            DK  EK   S ++   KSP  +   +  D    +K          +  +K   K+  ++
Sbjct: 778 ADKFPEK-AKSPVKEEVKSPEKAKSPLKEDAKAPEK----------EIPKKEEVKSPVKE 826

Query: 181 RKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVK 240
            +   E    +     E + AP     ++    + E+  +     K KV+E  KKE  V+
Sbjct: 827 EEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKK-EAPKPKVEE--KKEPAVE 883

Query: 241 SPVEKKEKKSKSKCN---ALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSA 297
            P E K +  K +      + T    APA V+ +  + PK+ +  +       + + PS 
Sbjct: 884 KPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK 943

Query: 298 ESKKPKWVPPAASGGSRSSSSP 319
            ++K +  P         +  P
Sbjct: 944 PAEKKEAAPEKKDTKEEKAKKP 965


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 76/343 (22%), Positives = 120/343 (34%), Gaps = 37/343 (10%)

Query: 4   PVRHKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEIPVQ 63
           P   KK ++  + +  +  +  +   V   +K +   KE  ++K KP      KE+I  +
Sbjct: 136 PPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKG--KEKVREKEKPEKKATHKEKIEKK 193

Query: 64  EKTPKKRLPEGTFSIPASAVPCTKMALDDKLYQRDLEVALALSVKELPTVTTNVQNSQDK 123
           EK   K L +       +     K   + K  +++     A  VKE+    +  +  +DK
Sbjct: 194 EKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDK 253

Query: 124 SIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKI 183
             EK   SK E   +    + C    D               V G  K     A      
Sbjct: 254 --EKAAVSKHE---QKDQYAFCRYMIDIF-------------VHGDLKPGQSPA------ 289

Query: 184 LLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPV 243
           +      + A+   P     E+ E +    E +   E     K  +K  KK E +    V
Sbjct: 290 IPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIK--KKSEKETAIDV 347

Query: 244 EKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSA--ESKK 301
           EKKE    S+       + +  AA K E +   KK       T+KP E+  P    + KK
Sbjct: 348 EKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKK-------TKKPAEVEQPKGKKQEKK 400

Query: 302 PKWVPPAASGGSRSSSSPLVVVSVKSPNQSLRLGLSRLARVKP 344
            K V PA S     S      V  K+      +G   + +  P
Sbjct: 401 EKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVP 443



 Score = 37.0 bits (84), Expect = 0.027
 Identities = 45/173 (26%), Positives = 67/173 (38%), Gaps = 17/173 (9%)

Query: 143 SNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDT-EPDFA 201
           S   + SD L L +  +E+    + G     S   + + +   E  DGD   D  E D  
Sbjct: 80  SIAKIGSDPLKLVRDAMEETTDWIYGFFSLLSDIISSEDE---EDDDGDEDTDKGEIDEP 136

Query: 202 PGEDSEDDSDFCESEDNDEDFSMRK--SKVKEIKKKEVKVKSPVEKK-------EKKSKS 252
           P    E   D  E ++  E     K   K KE  K++V+ K   EKK       EKK K 
Sbjct: 137 PLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKP 196

Query: 253 KCNALVTSVDSAPAAVKSESQSLPK----KVSLSSDTTRKPLEIRSPSAESKK 301
           +   L      A  A KSE ++  +    K      T  K  E++   ++ K+
Sbjct: 197 ETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKE 249



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 11/107 (10%)

Query: 199 DFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALV 258
           D    ED EDD       D DED    +     ++KKE+  K   EK+EK  + K    V
Sbjct: 112 DIISSEDEEDD-------DGDEDTDKGEIDEPPLRKKEIH-KDKTEKQEKPER-KIQTKV 162

Query: 259 TSVDSAPAAVKSESQSLPKKVSLSSDTTRK--PLEIRSPSAESKKPK 303
           T  +      K   +  P+K +   +   K    E ++ + E KK K
Sbjct: 163 THKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAK 209


>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b
            [Homo sapiens]
          Length = 1524

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 48/169 (28%), Positives = 77/169 (45%), Gaps = 12/169 (7%)

Query: 170  RKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESE-DNDEDFSMRKSK 228
            ++ + + +++QR  L    D + +   E D   G++ E  S+  E E + DED S  + +
Sbjct: 1166 KQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEE 1225

Query: 229  VKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRK 288
            V   K+   +V+ PV+ + K S S  +         P    S SQ    K ++SS T R 
Sbjct: 1226 VSLPKRGRPQVRLPVKTRGKLSSSFSS---RGQQQEPGRYPSRSQQSTPKTTVSSKTGRS 1282

Query: 289  PLEIRS-PSAESKKPKWVPPAASGGSRSSSSPL---VVVSVKSPNQSLR 333
              +I S P  E+K  +     AS  +R S  PL   V V + SP +  R
Sbjct: 1283 LRKINSAPPTETKSLR----IASRSTRHSHGPLQADVFVELLSPRRKRR 1327



 Score = 29.6 bits (65), Expect = 4.3
 Identities = 26/102 (25%), Positives = 49/102 (48%), Gaps = 13/102 (12%)

Query: 157 ITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESE 216
           I+ ED+V   Q      SKA  ++ K+L +      A      F   +   + +D  E++
Sbjct: 285 ISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLA------FEKAKLKREKADALEAK 338

Query: 217 DND-EDFSMRKSKVKEI------KKKEVKVKSPVEKKEKKSK 251
             + ED   ++ ++K+I      KKKE K +  VE+++++ K
Sbjct: 339 KKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREK 380


>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform a
            [Homo sapiens]
          Length = 1556

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 48/169 (28%), Positives = 77/169 (45%), Gaps = 12/169 (7%)

Query: 170  RKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESE-DNDEDFSMRKSK 228
            ++ + + +++QR  L    D + +   E D   G++ E  S+  E E + DED S  + +
Sbjct: 1198 KQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEE 1257

Query: 229  VKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRK 288
            V   K+   +V+ PV+ + K S S  +         P    S SQ    K ++SS T R 
Sbjct: 1258 VSLPKRGRPQVRLPVKTRGKLSSSFSS---RGQQQEPGRYPSRSQQSTPKTTVSSKTGRS 1314

Query: 289  PLEIRS-PSAESKKPKWVPPAASGGSRSSSSPL---VVVSVKSPNQSLR 333
              +I S P  E+K  +     AS  +R S  PL   V V + SP +  R
Sbjct: 1315 LRKINSAPPTETKSLR----IASRSTRHSHGPLQADVFVELLSPRRKRR 1359



 Score = 29.6 bits (65), Expect = 4.3
 Identities = 26/102 (25%), Positives = 49/102 (48%), Gaps = 13/102 (12%)

Query: 157 ITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESE 216
           I+ ED+V   Q      SKA  ++ K+L +      A      F   +   + +D  E++
Sbjct: 285 ISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLA------FEKAKLKREKADALEAK 338

Query: 217 DND-EDFSMRKSKVKEI------KKKEVKVKSPVEKKEKKSK 251
             + ED   ++ ++K+I      KKKE K +  VE+++++ K
Sbjct: 339 KKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREK 380


>gi|5453567 craniofacial development protein 1 [Homo sapiens]
          Length = 299

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 48/214 (22%), Positives = 88/214 (41%), Gaps = 38/214 (17%)

Query: 153 DLDKITVEDDVGG------VQGKRKAASKAAAQQRK---ILLEGSDGDSANDTEPDFAPG 203
           D++++  ED+V G       QGK++ A    A++R+   + LE  + + AN      + G
Sbjct: 29  DVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSE----SEG 84

Query: 204 EDSEDDSDFCESEDNDEDFSMRKSKVKEI---------KKKEVKVKSPVEKKEKKSKSKC 254
             SE++ D  E E        RK K  E+          K +V   + V+K E+  ++  
Sbjct: 85  SSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETSS 144

Query: 255 NALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKK------------- 301
           + L+   +      ++E   + K    + +  R   E+ + S E+K              
Sbjct: 145 SKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQAN 204

Query: 302 -PKWVP--PAASGGSRSSSSPLVVVSVKSPNQSL 332
            P  +P  PA SG  RSS    ++  + +  Q +
Sbjct: 205 VPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQKM 238


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 48/176 (27%), Positives = 81/176 (46%), Gaps = 25/176 (14%)

Query: 150 DYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDD 209
           +Y++ ++   E D  G + K+K   KA      IL E  D +S  + E      ++ ED 
Sbjct: 113 EYIEREESDGEYDEFG-RKKKKYRGKAVGPA-SILKEVEDKESEGEEE------DEDEDL 164

Query: 210 SDFCESEDNDED------FSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDS 263
           S +   ED DED      +++  S+ ++  KK+   +S  + +   S+S      +S  S
Sbjct: 165 SKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRS------SSRSS 218

Query: 264 APAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPKWVPPAASGGSRSSSSP 319
           +P++ +S S+S  +  S S   +R     RS S  SK       ++S   R SSSP
Sbjct: 219 SPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKS-----RSSSRSHRGSSSP 269


>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
          Length = 320

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 48/176 (27%), Positives = 81/176 (46%), Gaps = 25/176 (14%)

Query: 150 DYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDD 209
           +Y++ ++   E D  G + K+K   KA      IL E  D +S  + E      ++ ED 
Sbjct: 113 EYIEREESDGEYDEFG-RKKKKYRGKAVGPA-SILKEVEDKESEGEEE------DEDEDL 164

Query: 210 SDFCESEDNDED------FSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDS 263
           S +   ED DED      +++  S+ ++  KK+   +S  + +   S+S      +S  S
Sbjct: 165 SKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRS------SSRSS 218

Query: 264 APAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPKWVPPAASGGSRSSSSP 319
           +P++ +S S+S  +  S S   +R     RS S  SK       ++S   R SSSP
Sbjct: 219 SPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKS-----RSSSRSHRGSSSP 269


>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
           [Homo sapiens]
          Length = 517

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 52/241 (21%), Positives = 97/241 (40%), Gaps = 22/241 (9%)

Query: 95  YQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETMNKSPHISNCSVASDYLDL 154
           ++R  +V    S+ +   +    Q+  ++  EK G  K   +       +  ++SD  D 
Sbjct: 164 WERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDA 223

Query: 155 DKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCE 214
                 ++ G V   +K A  A   ++K   +GSD ++  D++     G++ +  SD   
Sbjct: 224 SG----EEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSS 279

Query: 215 SEDNDEDFSMRKSKVKEIKK----------KEVKVKSPVEKKEKKSKSKC---NALVTSV 261
           S   + +   +  + +E  K          +  + K P E KE++ + K           
Sbjct: 280 SSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRK 339

Query: 262 DSAPAAVKSESQSLPKKVSLSSDTTRK---PLEIRSPSAESKKPKWVP--PAASGGSRSS 316
           DS+  +  SE   +  + S +    +K   P   R PS  S +    P  P+A GGS SS
Sbjct: 340 DSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNSRPGTPSAEGGSTSS 399

Query: 317 S 317
           +
Sbjct: 400 T 400


>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
           sapiens]
          Length = 2168

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 8/98 (8%)

Query: 188 SDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKE 247
           SD +S +DTE     G + EDD D  + +++D D    K+ +K + K    VKSP     
Sbjct: 635 SDSNSESDTE-----GSEEEDDDDK-DQDESDSDTEGEKTSMK-LNKTTSSVKSPSMSLT 687

Query: 248 KKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDT 285
             S  +   +  +  SAPAA+ SESQS P  +  SS T
Sbjct: 688 GHSTPRNLHIAKAPGSAPAALCSESQS-PAFLGTSSST 724



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 27/129 (20%), Positives = 58/129 (44%), Gaps = 20/129 (15%)

Query: 180 QRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKV 239
           ++K +   S+ DS + T  D +    S  DSD  E ++ +ED S+ +S+  +        
Sbjct: 235 RKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSD------ 288

Query: 240 KSPVEKKEKKSKSKCNALVTSV-----DSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRS 294
                + E + KS    L+  +     D   A  K++ + + + + L+S++     +  S
Sbjct: 289 ----SESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIHQPLPLASES-----QTHS 339

Query: 295 PSAESKKPK 303
             ++ K+P+
Sbjct: 340 FQSQQKQPQ 348



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 47/191 (24%), Positives = 73/191 (38%), Gaps = 28/191 (14%)

Query: 167 QGKRKAASKAA--------AQQRKILLEGSDGDSANDTEPDFAPGEDSED------DSDF 212
           QGK KA S           +   K L+E   G     T+ D    +DSED      + D 
Sbjct: 562 QGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRG-----TDSDIPSSKDSEDSNEDEEEDDE 616

Query: 213 CESEDNDEDFSMRKSKVKEIKKKEVKVK-SPVEKKEKKSKSKCNALVTSVDSAPAAVKSE 271
            E E++DED     S+ +     E   + S  E  + K + + ++      ++    K+ 
Sbjct: 617 EEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTT 676

Query: 272 SQSLPKKVSLSSDTTRKPLEIRSPSAESKKPKWVPPAASGGSRSSSSPLVVVSVKSPNQS 331
           S      +SL+  +T + L I      +K P   P A    S S S   +  S  +   S
Sbjct: 677 SSVKSPSMSLTGHSTPRNLHI------AKAPGSAPAALC--SESQSPAFLGTSSSTLTSS 728

Query: 332 LRLGLSRLARV 342
              G S+  RV
Sbjct: 729 PHSGTSKRRRV 739



 Score = 28.5 bits (62), Expect = 9.5
 Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 10/57 (17%)

Query: 188  SDGDSANDTEPDFAPGEDSEDD----------SDFCESEDNDEDFSMRKSKVKEIKK 234
            SD D  +D + D    ED ED+          +D CE ED  +  +  +   K+I+K
Sbjct: 1297 SDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEKQIEK 1353


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
            sapiens]
          Length = 3969

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 13/110 (11%)

Query: 226  KSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDT 285
            + + K +KKKE K K+  +K  K+S    N + +S    P+A +  +   PKK S S   
Sbjct: 1207 QKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPA---PKKSS-SEPP 1262

Query: 286  TRKPLEIRS-------PSAESKKPKWVPPAASGGSRSSSSPLVVVSVKSP 328
             RKP+E +S       P  ESK+     PA+   S+  S P +V+  + P
Sbjct: 1263 PRKPVEEKSEEGNVSAPGPESKQA--TTPASRKSSKQVSQPALVIPPQPP 1310



 Score = 32.7 bits (73), Expect = 0.50
 Identities = 32/137 (23%), Positives = 56/137 (40%), Gaps = 7/137 (5%)

Query: 168 GKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSE-----DDSDFCESEDNDEDF 222
           G+    ++   +Q     E     S     P F PG  +E     D +    S+D D D 
Sbjct: 807 GESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADK 866

Query: 223 SMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLS 282
           S+ K K +E  ++  K      +KEK+ K   + + +S    P    S+ + + + V+ S
Sbjct: 867 SVEKDKSRERDREREKENKRESRKEKRKKG--SEIQSSSALYPVGRVSKEKVVGEDVATS 924

Query: 283 SDTTRKPLEIRSPSAES 299
           S   +     +S S +S
Sbjct: 925 SSAKKATGRKKSSSHDS 941



 Score = 28.9 bits (63), Expect = 7.3
 Identities = 52/238 (21%), Positives = 89/238 (37%), Gaps = 9/238 (3%)

Query: 86   TKMALDDKLYQRDLEVA--LALSVKELPTVTTNVQNSQDKSIEKHGSSKIETMNKSPHI- 142
            + M  DDK      E A  LA  +K +  VT N +  Q+  ++K   S+         + 
Sbjct: 1106 SSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRN-KAPQEPPVKKGRRSRRCGQCPGCQVP 1164

Query: 143  SNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAP 202
             +C V ++ LD  K    +        RK  +      +  L + +      + +   + 
Sbjct: 1165 EDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSE 1224

Query: 203  GEDSEDDSDFCESEDNDEDF--SMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTS 260
             +DS++ S      D+ +    S R+    +    E   + PVE+K ++         + 
Sbjct: 1225 KKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESK 1284

Query: 261  VDSAPAAVKSESQ-SLPKKVSLSSDTTRKP--LEIRSPSAESKKPKWVPPAASGGSRS 315
              + PA+ KS  Q S P  V      T  P   E+   +    K K  PP  SG  +S
Sbjct: 1285 QATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQS 1342


>gi|4507241 structure specific recognition protein 1 [Homo sapiens]
          Length = 709

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 34/132 (25%), Positives = 61/132 (46%), Gaps = 20/132 (15%)

Query: 188 SDGDSANDTEPDFAPGEDSEDDSD------FCESEDNDEDFSMRKSKVKEIKKKEV---- 237
           S  DS  +T+  F PGE+ ED ++         S  N+ D    + K K++KK ++    
Sbjct: 470 SSDDSGEETDESFNPGEEEEDVAEEFDSNASASSSSNEGDSDRDEKKRKQLKKAKMAKDR 529

Query: 238 -KVKSPVEKKEKKS----KSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEI 292
              K PVE K+ K     K   +A +  ++++   +KS+   +       +D ++K  EI
Sbjct: 530 KSRKKPVEVKKGKDPNAPKRPMSAYMLWLNASREKIKSDHPGIS-----ITDLSKKAGEI 584

Query: 293 RSPSAESKKPKW 304
               ++ KK +W
Sbjct: 585 WKGMSKEKKEEW 596


>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
          Length = 888

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 62/258 (24%), Positives = 106/258 (41%), Gaps = 32/258 (12%)

Query: 19  SDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEIPVQEKTPKKRLPEGTFS- 77
           + ++++ +S+   L K  +   +E  +   K       KE+   +EK  +K   + T S 
Sbjct: 83  NSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEKEKEKEREKEKEKATVSE 142

Query: 78  -IPASAVPCTKMALDDKLYQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETM 136
            + ASA   T                   +V   P+V T    ++++  E     K    
Sbjct: 143 NVAASAAATTPATSPP-------------AVNTSPSVPTTTTATEEQVSEP---KKWNLR 186

Query: 137 NKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDT 196
              P +   S+  +  D+D    EDD        K   ++A+Q+     EGSDGD  N+ 
Sbjct: 187 RNRPLLDFVSM-EELNDMDDYDSEDDNDWRPTVVKRKGRSASQK-----EGSDGD--NED 238

Query: 197 EPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNA 256
           + D   G D ED++D    E NDED S   S+    KKK+ KV S     +++  +    
Sbjct: 239 DEDEGSGSD-EDEND----EGNDEDHSSPASE-GGCKKKKSKVLSRNSADDEELTNDSLT 292

Query: 257 LVTSVDSAPAAVKSESQS 274
           L  S  +  + +  +SQ+
Sbjct: 293 LSQSKSNEDSLILEKSQN 310



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 15/135 (11%)

Query: 169 KRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSK 228
           KR+     AA     LLE  D DS++D+  DF  G+ S+ +     SED  +D       
Sbjct: 6   KRRQVKPLAAS----LLEALDYDSSDDS--DFKVGDASDSEGSGNGSEDASKDSGEGSCS 59

Query: 229 VKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRK 288
             E    E ++   ++ KE++ K+     V S         SE Q +  +     +   +
Sbjct: 60  DSEENILEEELNEDIKVKEEQLKNSAEEEVLS---------SEKQLIKMEKKEEEENGER 110

Query: 289 PLEIRSPSAESKKPK 303
           P + +    E +K K
Sbjct: 111 PRKKKEKEKEKEKEK 125



 Score = 30.0 bits (66), Expect = 3.3
 Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 10/105 (9%)

Query: 194 NDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSK 253
           N  E +    E      +  E E+N E    +K K KE +K++       EK++++ K K
Sbjct: 83  NSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEK-------EKEKEREKEK 135

Query: 254 CNALVTSVDSAPAAVKSESQSLP---KKVSLSSDTTRKPLEIRSP 295
             A V+   +A AA  + + S P      S+ + TT    ++  P
Sbjct: 136 EKATVSENVAASAAATTPATSPPAVNTSPSVPTTTTATEEQVSEP 180


>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
          Length = 948

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 62/258 (24%), Positives = 106/258 (41%), Gaps = 32/258 (12%)

Query: 19  SDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEIPVQEKTPKKRLPEGTFS- 77
           + ++++ +S+   L K  +   +E  +   K       KE+   +EK  +K   + T S 
Sbjct: 83  NSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEKEKEKEREKEKEKATVSE 142

Query: 78  -IPASAVPCTKMALDDKLYQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETM 136
            + ASA   T                   +V   P+V T    ++++  E     K    
Sbjct: 143 NVAASAAATTPATSPP-------------AVNTSPSVPTTTTATEEQVSEP---KKWNLR 186

Query: 137 NKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDT 196
              P +   S+  +  D+D    EDD        K   ++A+Q+     EGSDGD  N+ 
Sbjct: 187 RNRPLLDFVSM-EELNDMDDYDSEDDNDWRPTVVKRKGRSASQK-----EGSDGD--NED 238

Query: 197 EPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNA 256
           + D   G D ED++D    E NDED S   S+    KKK+ KV S     +++  +    
Sbjct: 239 DEDEGSGSD-EDEND----EGNDEDHSSPASE-GGCKKKKSKVLSRNSADDEELTNDSLT 292

Query: 257 LVTSVDSAPAAVKSESQS 274
           L  S  +  + +  +SQ+
Sbjct: 293 LSQSKSNEDSLILEKSQN 310



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 15/135 (11%)

Query: 169 KRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSK 228
           KR+     AA     LLE  D DS++D+  DF  G+ S+ +     SED  +D       
Sbjct: 6   KRRQVKPLAAS----LLEALDYDSSDDS--DFKVGDASDSEGSGNGSEDASKDSGEGSCS 59

Query: 229 VKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRK 288
             E    E ++   ++ KE++ K+     V S         SE Q +  +     +   +
Sbjct: 60  DSEENILEEELNEDIKVKEEQLKNSAEEEVLS---------SEKQLIKMEKKEEEENGER 110

Query: 289 PLEIRSPSAESKKPK 303
           P + +    E +K K
Sbjct: 111 PRKKKEKEKEKEKEK 125



 Score = 30.0 bits (66), Expect = 3.3
 Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 10/105 (9%)

Query: 194 NDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSK 253
           N  E +    E      +  E E+N E    +K K KE +K++       EK++++ K K
Sbjct: 83  NSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEK-------EKEKEREKEK 135

Query: 254 CNALVTSVDSAPAAVKSESQSLP---KKVSLSSDTTRKPLEIRSP 295
             A V+   +A AA  + + S P      S+ + TT    ++  P
Sbjct: 136 EKATVSENVAASAAATTPATSPPAVNTSPSVPTTTTATEEQVSEP 180


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 63/297 (21%), Positives = 111/297 (37%), Gaps = 31/297 (10%)

Query: 8   KKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLR-KEEIPVQEKT 66
           K P+  S  +         S T P ++ S+T  K   Q   K + N+ +   E    +  
Sbjct: 160 KTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNN 219

Query: 67  PKKRLPEGTFSIPASAVPCTKMALDDKLYQRDLEVALALSVKELPTVTTNVQNSQDKSIE 126
           PKK L     S    +  C++ +L+                         V  S D+SI 
Sbjct: 220 PKKDLKRSKTSNDPISEICSENSLNVDFLML-------------------VGQSDDESIN 260

Query: 127 KHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLE 186
                +  + N S + S        L   K T +D     +    A S+ +   +K   +
Sbjct: 261 FDAWLRNYSQNNSKNYS--------LKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKK 312

Query: 187 GSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKK 246
                  +D + D     +S  D++  +S+D  +D    K K+K+  KK+   K P E  
Sbjct: 313 VKKNVKKDDKKKDVKKDTES-TDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYP-EST 370

Query: 247 EKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPK 303
           + +S    +A   S +   A+   + +   KK++ S+D +   LE +    + KK K
Sbjct: 371 DTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTD-SESELESKESQKDEKKDK 426


>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 3 [Homo sapiens]
          Length = 568

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 68/330 (20%), Positives = 123/330 (37%), Gaps = 69/330 (20%)

Query: 7   HKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEIPVQEKT 66
           HK+  +    +H  +   F   +   NK S+ + K+ K++KP      + K      +  
Sbjct: 203 HKEKPSKDSREHKSA---FKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPM 259

Query: 67  PKKRLPEGTFSIPASA----VPCTKMALDD------KLYQRDLEVALALSVKELP----T 112
            K+  P+       S      P  +  + D      K  ++    AL  S    P    T
Sbjct: 260 SKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILT 319

Query: 113 VTTNVQNSQDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKA 172
            + + +  +DKS  K G  KIE+       S      D +D +   VE+++         
Sbjct: 320 CSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENI--------- 370

Query: 173 ASKAAAQQRKILLEGSDGDSANDTEPDFAPGE-----------------DSEDDSDFCES 215
           +SK+ ++Q       S   S++ +   F P +                 D+E++SD  E 
Sbjct: 371 SSKSDSEQP------SPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVED 424

Query: 216 EDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSL 275
            DND +                 ++ PV +    S+S+  +L    DS  ++  S     
Sbjct: 425 NDNDSE-----------------MERPVNR--GGSRSRRVSLSDGSDSESSSASSPLHHE 465

Query: 276 PKKVSLSSDTTRKPLEIRSPSAESKKPKWV 305
           P    L ++   + LE++SP  +SK  K +
Sbjct: 466 PPPPLLKTN-NNQILEVKSPIKQSKSDKQI 494


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 58/257 (22%), Positives = 105/257 (40%), Gaps = 37/257 (14%)

Query: 61  PVQEKTPKKRLPEGTFSIPASAVPCTKMALDDKLYQRDLEVALALSVKELPTVTTNVQNS 120
           PV ++T  K+  +   S+  +A P    ++  +  +   EV     V++ P     V++ 
Sbjct: 528 PVVKQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPP----KVESK 583

Query: 121 QDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQG---KRKAASKAA 177
           +   ++K    K ET    P ++   V S     +   V+ +V   Q    K KAA +  
Sbjct: 584 EKVMVKKDKPIKTET---KPSVTEKEVPSKE---EPSPVKAEVAEKQATDVKPKAAKEKT 637

Query: 178 AQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKK--- 234
            ++   +      +     + + A  ED        + E+  +   ++K   KEIKK   
Sbjct: 638 VKKETKVKPEDKKEEKEKPKKEVAKKEDKTP----IKKEEKPKKEEVKKEVKKEIKKEEK 693

Query: 235 ----KEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPL 290
               KEVK ++P ++ +K+ K +    V   +  P   K E + LPK    SS       
Sbjct: 694 KEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEP---KKEIKKLPKDAKKSS------- 743

Query: 291 EIRSPSAESKKPKWVPP 307
              +P +E+KKP  + P
Sbjct: 744 ---TPLSEAKKPAALKP 757



 Score = 28.9 bits (63), Expect = 7.3
 Identities = 16/53 (30%), Positives = 27/53 (50%), Gaps = 5/53 (9%)

Query: 35  KSRTAPKELKQDKPKPNLNNLRKEEIPVQEKTPKKRLPEGTFSIPASAVPCTK 87
           K  T PKE+K++  K       K+E+  +EK PKK + +       S+ P ++
Sbjct: 701 KKETPPKEVKKEVKKE-----EKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSE 748


>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
           sapiens]
          Length = 1082

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 27/116 (23%), Positives = 52/116 (44%)

Query: 186 EGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEK 245
           E +D D  +++E D     +S       ES++ D+D    K +  E ++ E   K   +K
Sbjct: 689 ESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKK 748

Query: 246 KEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKK 301
           K  + K + ++     DS+ ++ +SE  S  ++  L   +  +     S SA + K
Sbjct: 749 KVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSKSAPATK 804



 Score = 28.9 bits (63), Expect = 7.3
 Identities = 32/138 (23%), Positives = 55/138 (39%), Gaps = 13/138 (9%)

Query: 188 SDGDSANDTEP---DFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVE 244
           S+ DS + +E    + +   D+ED     + ED ++       + +E  K++ K K P  
Sbjct: 699 SESDSKSSSESGSGESSSESDNED-----QDEDEEKGRGSESEQSEEDGKRKTKKKVPER 753

Query: 245 KKEKKSKSKCNALVTSVDSAPAAVKSESQSL-----PKKVSLSSDTTRKPLEIRSPSAES 299
           K E  S  + +   +S   +    +SE + L      +K   SS +     EI     E 
Sbjct: 754 KGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSKSAPATKEISLLDLED 813

Query: 300 KKPKWVPPAASGGSRSSS 317
             P  V P +     S+S
Sbjct: 814 FTPPSVQPVSPPAIVSTS 831


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 49/252 (19%), Positives = 99/252 (39%), Gaps = 17/252 (6%)

Query: 35  KSRTAPKELKQDKPKPNLNNLRKEEIPVQEKTPKKR--LPEGTFSIPASAVPCTKMALDD 92
           K R +  E  ++ PKP +++   EE P  + +  +   LP+   S   S  P    A D 
Sbjct: 205 KPRMSDSE-SEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDS 263

Query: 93  KLYQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETMNKSPHISNCSVASDYL 152
           +              +ELP    +   S+D    +   S+ E + K P +S+        
Sbjct: 264 EN-------------EELPKPRISDSESEDPPRNQASDSENEELPK-PRVSDSESEGPQK 309

Query: 153 DLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDF 212
                +  +D    + K ++   +  + +    E  +    +D+  D      S+ + + 
Sbjct: 310 GPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEE 369

Query: 213 CESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSES 272
            + +  D D   ++ + +++ K++  V S  E +EK S  K   +  + DS   AV  +S
Sbjct: 370 HKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKS 429

Query: 273 QSLPKKVSLSSD 284
               K ++  S+
Sbjct: 430 GKREKTIASDSE 441



 Score = 32.3 bits (72), Expect = 0.66
 Identities = 46/206 (22%), Positives = 82/206 (39%), Gaps = 23/206 (11%)

Query: 120 SQDKSIEKHG----SSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASK 175
           S   S+E+H     S + + + K  H+++ S   + L+L+    E +    Q    + S+
Sbjct: 40  SDTGSVERHSENETSDREDGLPKGHHVTD-SENDEPLNLNASDSESEELHRQKDSDSESE 98

Query: 176 AAAQQRKILLEGSD----GDSANDTEPDFAPGEDSEDDS--DFCESEDNDEDFSMRK--- 226
             A+      E  D    G  +   E    PG DSE++   +   S+  +ED        
Sbjct: 99  ERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDSENEDVGKHPASD 158

Query: 227 SKVKEIKKK-------EVKVKSPVEKKEKKSKSKCNALVTSVDSAPAA--VKSESQSLPK 277
           S+++E++K        E  +K  +   E +   +  A  +  +  P      SES+ LPK
Sbjct: 159 SEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPK 218

Query: 278 KVSLSSDTTRKPLEIRSPSAESKKPK 303
                S++   P    S S   + PK
Sbjct: 219 PQVSDSESEEPPRHQASDSENEELPK 244


>gi|48255931 hepatoma-derived growth factor-related protein 2
           isoform 1 [Homo sapiens]
          Length = 671

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 48/193 (24%), Positives = 80/193 (41%), Gaps = 26/193 (13%)

Query: 146 SVASDYLDLDKITVED-DVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGE 204
           + ASD ++ D  + +  D  G+  KRK  +   +  ++     SD D A+      +P E
Sbjct: 134 TAASDRMESDSDSDKSSDNSGL--KRKTPALKMSVSKRARKASSDLDQAS-----VSPSE 186

Query: 205 DSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPV---EKKEKKSKSKCNALVTSV 261
           +   +S     + +D+DF+  K       ++      P+   +KK+  S S  ++   S 
Sbjct: 187 EENSESSSESEKTSDQDFTPEKKAAVRAPRR-----GPLGGRKKKKAPSASDSDSKADSD 241

Query: 262 DSAP---AAVKSESQSLPKKVSLSSDTT-------RKPLEIRSPSAESKKPKWVPPAASG 311
            + P   A  +S S S     S  SD +       RKP E   P    +KPK   P +S 
Sbjct: 242 GAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSS 301

Query: 312 GSRSSSSPLVVVS 324
            S S S  +  +S
Sbjct: 302 SSDSDSDEVDRIS 314



 Score = 35.8 bits (81), Expect = 0.059
 Identities = 52/206 (25%), Positives = 77/206 (37%), Gaps = 55/206 (26%)

Query: 188 SDGDSANDTEPD-----------FAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKE 236
           +DG  A++ + D            A  +  E DSD  +S DN             +K+K 
Sbjct: 111 ADGSDADEDDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNSG-----------LKRKT 159

Query: 237 VKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSP- 295
             +K  V K+ +K+ S  +    S         SES S  +K S    T  K   +R+P 
Sbjct: 160 PALKMSVSKRARKASSDLDQASVSPSEEE---NSESSSESEKTSDQDFTPEKKAAVRAPR 216

Query: 296 ----------------------SAESKKPKWVPPA--ASGGSRSSSSPLVVVSVKSPNQS 331
                                  ++  KP+ V  A  AS  S SSSS    VSVK P + 
Sbjct: 217 RGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRG 276

Query: 332 LR-----LGLSRLARVKPLHPNATST 352
            +     L   R  + KP  P ++S+
Sbjct: 277 RKPAEKPLPKPRGRKPKPERPPSSSS 302


>gi|14249158 hepatoma-derived growth factor-related protein 2
           isoform 2 [Homo sapiens]
          Length = 670

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 48/193 (24%), Positives = 80/193 (41%), Gaps = 26/193 (13%)

Query: 146 SVASDYLDLDKITVED-DVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGE 204
           + ASD ++ D  + +  D  G+  KRK  +   +  ++     SD D A+      +P E
Sbjct: 134 TAASDRMESDSDSDKSSDNSGL--KRKTPALKMSVSKRARKASSDLDQAS-----VSPSE 186

Query: 205 DSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPV---EKKEKKSKSKCNALVTSV 261
           +   +S     + +D+DF+  K       ++      P+   +KK+  S S  ++   S 
Sbjct: 187 EENSESSSESEKTSDQDFTPEKKAAVRAPRR-----GPLGGRKKKKAPSASDSDSKADSD 241

Query: 262 DSAP---AAVKSESQSLPKKVSLSSDTT-------RKPLEIRSPSAESKKPKWVPPAASG 311
            + P   A  +S S S     S  SD +       RKP E   P    +KPK   P +S 
Sbjct: 242 GAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSS 301

Query: 312 GSRSSSSPLVVVS 324
            S S S  +  +S
Sbjct: 302 SSDSDSDEVDRIS 314



 Score = 35.8 bits (81), Expect = 0.059
 Identities = 52/206 (25%), Positives = 77/206 (37%), Gaps = 55/206 (26%)

Query: 188 SDGDSANDTEPD-----------FAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKE 236
           +DG  A++ + D            A  +  E DSD  +S DN             +K+K 
Sbjct: 111 ADGSDADEDDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNSG-----------LKRKT 159

Query: 237 VKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSP- 295
             +K  V K+ +K+ S  +    S         SES S  +K S    T  K   +R+P 
Sbjct: 160 PALKMSVSKRARKASSDLDQASVSPSEEE---NSESSSESEKTSDQDFTPEKKAAVRAPR 216

Query: 296 ----------------------SAESKKPKWVPPA--ASGGSRSSSSPLVVVSVKSPNQS 331
                                  ++  KP+ V  A  AS  S SSSS    VSVK P + 
Sbjct: 217 RGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRG 276

Query: 332 LR-----LGLSRLARVKPLHPNATST 352
            +     L   R  + KP  P ++S+
Sbjct: 277 RKPAEKPLPKPRGRKPKPERPPSSSS 302


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 42/168 (25%), Positives = 67/168 (39%), Gaps = 3/168 (1%)

Query: 150 DYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDD 209
           DYL+  + T E+    ++ K K  SKA A+  + + E    +     E   +  E S   
Sbjct: 32  DYLNRPRPTWEEVKKQLENK-KTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKK 90

Query: 210 SDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVK 269
            +  +        S   S   +        +   +K+ K+ K K N    S  S+    +
Sbjct: 91  RERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESE 150

Query: 270 SESQSLPKKVSLSSDTTRKPLEIRSPSAESKK--PKWVPPAASGGSRS 315
           SES+   KK   S D T K  ++RS S + KK  P   P ++   S S
Sbjct: 151 SESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSES 198



 Score = 29.6 bits (65), Expect = 4.3
 Identities = 38/139 (27%), Positives = 56/139 (40%), Gaps = 23/139 (16%)

Query: 118 QNSQDKSIEKHGSSKIETMNKSPHISNC----SVASDYLDLDKITVEDDVGGVQGKRKAA 173
           +  Q K  +K  +   ++   S H S      SV       D+   E DV  +  KRK  
Sbjct: 124 EKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRK-- 181

Query: 174 SKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIK 233
            K+    + +    S+  S +D E D    +        CE  +        K KVK+ K
Sbjct: 182 -KSYPDDKPL---SSESSSESDYEEDVQAKKKRR-----CEEREQ------AKEKVKKKK 226

Query: 234 KKEVKVKSPVEKKEKKSKS 252
           KK+ K  S  +KK+KKS S
Sbjct: 227 KKQHKKHS--KKKKKKSGS 243


>gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]
          Length = 871

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 6/135 (4%)

Query: 186 EGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEK 245
           EG  G    D E      ++ ++D    E++ +++D    K+K  E    + + K   EK
Sbjct: 288 EGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDD----KTKKSEGDGDKEEKKEDSEK 343

Query: 246 KEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPKWV 305
           + KKS  K N   +  DS      SES+S  +  S  ++  ++  E      + K+ +W 
Sbjct: 344 EAKKSSKKRNRKHSGDDSFDEGSVSESES--ESESGQAEEEKEEAEALKEKEKPKEEEWE 401

Query: 306 PPAASGGSRSSSSPL 320
            P  + G      PL
Sbjct: 402 KPKDAAGLECKPRPL 416


>gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens]
          Length = 875

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 6/135 (4%)

Query: 186 EGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEK 245
           EG  G    D E      ++ ++D    E++ +++D    K+K  E    + + K   EK
Sbjct: 288 EGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDD----KTKKSEGDGDKEEKKEDSEK 343

Query: 246 KEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPKWV 305
           + KKS  K N   +  DS      SES+S  +  S  ++  ++  E      + K+ +W 
Sbjct: 344 EAKKSSKKRNRKHSGDDSFDEGSVSESES--ESESGQAEEEKEEAEALKEKEKPKEEEWE 401

Query: 306 PPAASGGSRSSSSPL 320
            P  + G      PL
Sbjct: 402 KPKDAAGLECKPRPL 416


>gi|157266334 tubby like protein 1 [Homo sapiens]
          Length = 542

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 30/131 (22%), Positives = 61/131 (46%), Gaps = 9/131 (6%)

Query: 201 APGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSK-CNALVT 259
           AP  + E++ +  + ED +E+   +K K+    KK ++ KS  + KE+++K++     + 
Sbjct: 111 APDAEDEEEEEEEDEEDEEEEAEEKKEKILLPPKKPLREKSSADLKERRAKAQGPRGDLG 170

Query: 260 SVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPKWVPPAASGGSRSSSSP 319
           S D  P  ++  ++  P         T+K       S E+ K    P  +   +R S + 
Sbjct: 171 SPDPPPKPLRVRNKEAPAGEGTKMRKTKK-----KGSGEADKD---PSGSPASARKSPAA 222

Query: 320 LVVVSVKSPNQ 330
           + +V   SP++
Sbjct: 223 MFLVGEGSPDK 233


>gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens]
          Length = 872

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 37/138 (26%), Positives = 55/138 (39%), Gaps = 11/138 (7%)

Query: 186 EGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEK 245
           EG  G    D E      ++ ++D    E++ +++D    K+K  E    + + K   EK
Sbjct: 288 EGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDD----KTKKSEGDGDKEEKKEDSEK 343

Query: 246 KEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPK-- 303
           + KKS  K N   +  DS      SES+S     S S     +  E      E +KPK  
Sbjct: 344 EAKKSSKKRNRKHSGDDSFDEGSVSESES----ESESGQAEEEKEEAEEALKEKEKPKEE 399

Query: 304 -WVPPAASGGSRSSSSPL 320
            W  P  + G      PL
Sbjct: 400 EWEKPKDAAGLECKPRPL 417


>gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens]
          Length = 876

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 37/138 (26%), Positives = 55/138 (39%), Gaps = 11/138 (7%)

Query: 186 EGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEK 245
           EG  G    D E      ++ ++D    E++ +++D    K+K  E    + + K   EK
Sbjct: 288 EGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDD----KTKKSEGDGDKEEKKEDSEK 343

Query: 246 KEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPK-- 303
           + KKS  K N   +  DS      SES+S     S S     +  E      E +KPK  
Sbjct: 344 EAKKSSKKRNRKHSGDDSFDEGSVSESES----ESESGQAEEEKEEAEEALKEKEKPKEE 399

Query: 304 -WVPPAASGGSRSSSSPL 320
            W  P  + G      PL
Sbjct: 400 EWEKPKDAAGLECKPRPL 417


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 8/94 (8%)

Query: 160 EDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDND 219
           E+ +     K K A+K    + K + E  D +  ++ E D    +D EDD D  + +D +
Sbjct: 208 EEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDD----DDDEDDEDDDDEDDEE 263

Query: 220 EDFSMRKSKVKEI----KKKEVKVKSPVEKKEKK 249
           E+    +  VKE     KK+  K K+  E K++K
Sbjct: 264 EEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQK 297



 Score = 33.1 bits (74), Expect = 0.38
 Identities = 28/113 (24%), Positives = 52/113 (46%), Gaps = 9/113 (7%)

Query: 168 GKRKAA--SKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMR 225
           GK+ AA  +K A   +    E SD +  +D+E      ED EDD D  E ED  E  +M+
Sbjct: 123 GKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSE------EDEEDDEDEDEDEDEIEPAAMK 176

Query: 226 KSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKK 278
            +      + E   +   + ++     + ++   ++++ PA  K  ++ +P K
Sbjct: 177 AAAAAPASEDE-DDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVK 228



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 6/68 (8%)

Query: 157 ITVEDDVGGVQGKRKAAS---KAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFC 213
           +T     G   GK   A+   K AA   K      +G +A   + D    +DSE+D +  
Sbjct: 104 VTTPGKKGATPGKALVATPGKKGAAIPAK---GAKNGKNAKKEDSDEEEDDDSEEDEEDD 160

Query: 214 ESEDNDED 221
           E ED DED
Sbjct: 161 EDEDEDED 168



 Score = 28.5 bits (62), Expect = 9.5
 Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 1/93 (1%)

Query: 190 GDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKK 249
           G +  D +    P ++ E+DS+  E  +++ED S  +  V   +KK  K  +   KK   
Sbjct: 8   GKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIP-QKKGKKAAATSAKKVVV 66

Query: 250 SKSKCNALVTSVDSAPAAVKSESQSLPKKVSLS 282
           S +K  A+ T    A      ++ + P K +++
Sbjct: 67  SPTKKVAVATPAKKAAVTPGKKAAATPAKKTVT 99


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.305    0.122    0.331 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,830,286
Number of Sequences: 37866
Number of extensions: 664715
Number of successful extensions: 5267
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 112
Number of HSP's successfully gapped in prelim test: 377
Number of HSP's that attempted gapping in prelim test: 3626
Number of HSP's gapped (non-prelim): 1493
length of query: 352
length of database: 18,247,518
effective HSP length: 103
effective length of query: 249
effective length of database: 14,347,320
effective search space: 3572482680
effective search space used: 3572482680
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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