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Search of human proteins with 19115954
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
(4624 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] 9206 0.0
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens] 5675 0.0
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 2199 0.0
gi|75677365 dynein heavy chain domain 3 [Homo sapiens] 2141 0.0
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens] 2020 0.0
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 1950 0.0
gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 1921 0.0
gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 1921 0.0
gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap... 1920 0.0
gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 1918 0.0
gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens] 1892 0.0
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] 1868 0.0
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens] 1831 0.0
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] 1355 0.0
gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens] 1184 0.0
gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens] 916 0.0
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H... 776 0.0
gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sap... 445 e-124
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] 179 6e-44
gi|4758648 kinesin family member 5B [Homo sapiens] 48 2e-04
gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 47 3e-04
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 47 3e-04
gi|55770834 centromere protein F [Homo sapiens] 47 4e-04
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 47 6e-04
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 46 8e-04
gi|122937396 coiled-coil domain containing 150 [Homo sapiens] 46 8e-04
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 46 0.001
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 45 0.001
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 45 0.001
gi|93102364 SWAP-70 protein [Homo sapiens] 45 0.002
>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
Length = 4624
Score = 9206 bits (23889), Expect = 0.0
Identities = 4624/4624 (100%), Positives = 4624/4624 (100%)
Query: 1 MFRIGRRQLWKHSVTRVLTQRLKGEKEAKRALLDARHNYLFAIVASCLDLNKTEVEDAIL 60
MFRIGRRQLWKHSVTRVLTQRLKGEKEAKRALLDARHNYLFAIVASCLDLNKTEVEDAIL
Sbjct: 1 MFRIGRRQLWKHSVTRVLTQRLKGEKEAKRALLDARHNYLFAIVASCLDLNKTEVEDAIL 60
Query: 61 EGNQIERIDQLFAVGGLRHLMFYYQDVEEAETGQLGSLGGVNLVSGKIKKPKVFVTEGND 120
EGNQIERIDQLFAVGGLRHLMFYYQDVEEAETGQLGSLGGVNLVSGKIKKPKVFVTEGND
Sbjct: 61 EGNQIERIDQLFAVGGLRHLMFYYQDVEEAETGQLGSLGGVNLVSGKIKKPKVFVTEGND 120
Query: 121 VALTGVCVFFIRTDPSKAITPDNIHQEVSFNMLDAADGGLLNSVRRLLSDIFIPALRATS 180
VALTGVCVFFIRTDPSKAITPDNIHQEVSFNMLDAADGGLLNSVRRLLSDIFIPALRATS
Sbjct: 121 VALTGVCVFFIRTDPSKAITPDNIHQEVSFNMLDAADGGLLNSVRRLLSDIFIPALRATS 180
Query: 181 HGWGELEGLQDAANIRQEFLSSLEGFVNVLSGAQESLKEKVNLRKCDILELKTLKEPTDY 240
HGWGELEGLQDAANIRQEFLSSLEGFVNVLSGAQESLKEKVNLRKCDILELKTLKEPTDY
Sbjct: 181 HGWGELEGLQDAANIRQEFLSSLEGFVNVLSGAQESLKEKVNLRKCDILELKTLKEPTDY 240
Query: 241 LTLANNPETLGKIEDCMKVWIKQTEQVLAENNQLLKEADDVGPRAELEHWKKRLSKFNYL 300
LTLANNPETLGKIEDCMKVWIKQTEQVLAENNQLLKEADDVGPRAELEHWKKRLSKFNYL
Sbjct: 241 LTLANNPETLGKIEDCMKVWIKQTEQVLAENNQLLKEADDVGPRAELEHWKKRLSKFNYL 300
Query: 301 LEQLKSPDVKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLEKCCDPLYS 360
LEQLKSPDVKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLEKCCDPLYS
Sbjct: 301 LEQLKSPDVKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLEKCCDPLYS 360
Query: 361 SDPLSMMDAIPTLINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAYITNNGTASI 420
SDPLSMMDAIPTLINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAYITNNGTASI
Sbjct: 361 SDPLSMMDAIPTLINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAYITNNGTASI 420
Query: 421 WNQPQDVVEEKILSAIKLKQEYQLCFHKTKQKLKQNPNAKQFDFSEMYIFGKFETFHRRL 480
WNQPQDVVEEKILSAIKLKQEYQLCFHKTKQKLKQNPNAKQFDFSEMYIFGKFETFHRRL
Sbjct: 421 WNQPQDVVEEKILSAIKLKQEYQLCFHKTKQKLKQNPNAKQFDFSEMYIFGKFETFHRRL 480
Query: 481 AKIIDIFTTLKTYSVLQDSTIEGLEDMATKYQGIVATIKKKEYNFLDQRKMDFDQDYEEF 540
AKIIDIFTTLKTYSVLQDSTIEGLEDMATKYQGIVATIKKKEYNFLDQRKMDFDQDYEEF
Sbjct: 481 AKIIDIFTTLKTYSVLQDSTIEGLEDMATKYQGIVATIKKKEYNFLDQRKMDFDQDYEEF 540
Query: 541 CKQTNDLHNELRKFMDVTFAKIQNTNQALRMLKKFERLNIPNLGIDDKYQLILENYGADI 600
CKQTNDLHNELRKFMDVTFAKIQNTNQALRMLKKFERLNIPNLGIDDKYQLILENYGADI
Sbjct: 541 CKQTNDLHNELRKFMDVTFAKIQNTNQALRMLKKFERLNIPNLGIDDKYQLILENYGADI 600
Query: 601 DMISKLYTKQKYDPPLARNQPPIAGKILWARQLFHRIQQPMQLFQQHPAVLSTAEAKPII 660
DMISKLYTKQKYDPPLARNQPPIAGKILWARQLFHRIQQPMQLFQQHPAVLSTAEAKPII
Sbjct: 601 DMISKLYTKQKYDPPLARNQPPIAGKILWARQLFHRIQQPMQLFQQHPAVLSTAEAKPII 660
Query: 661 RSYNRMAKVLLEFEVLFHRAWLRQIEEIHVGLEASLLVKAPGTGELFVNFDPQILILFRE 720
RSYNRMAKVLLEFEVLFHRAWLRQIEEIHVGLEASLLVKAPGTGELFVNFDPQILILFRE
Sbjct: 661 RSYNRMAKVLLEFEVLFHRAWLRQIEEIHVGLEASLLVKAPGTGELFVNFDPQILILFRE 720
Query: 721 TECMAQMGLEVSPLATSLFQKRDRYKRNFSNMKMMLAEYQRVKSKIPAAIEQLIVPHLAK 780
TECMAQMGLEVSPLATSLFQKRDRYKRNFSNMKMMLAEYQRVKSKIPAAIEQLIVPHLAK
Sbjct: 721 TECMAQMGLEVSPLATSLFQKRDRYKRNFSNMKMMLAEYQRVKSKIPAAIEQLIVPHLAK 780
Query: 781 VDEALQPGLAALTWTSLNIEAYLENTFAKIKDLELLLDRVNDLIEFRIDAILEEMSSTPL 840
VDEALQPGLAALTWTSLNIEAYLENTFAKIKDLELLLDRVNDLIEFRIDAILEEMSSTPL
Sbjct: 781 VDEALQPGLAALTWTSLNIEAYLENTFAKIKDLELLLDRVNDLIEFRIDAILEEMSSTPL 840
Query: 841 CQLPQEEPLTCEEFLQMTKDLCVNGAQILHFKSSLVEEAVNELVNMLLDVEVLSEEESEK 900
CQLPQEEPLTCEEFLQMTKDLCVNGAQILHFKSSLVEEAVNELVNMLLDVEVLSEEESEK
Sbjct: 841 CQLPQEEPLTCEEFLQMTKDLCVNGAQILHFKSSLVEEAVNELVNMLLDVEVLSEEESEK 900
Query: 901 ISNENSVNYKNESSAKREEGNFDTLTSSINARANALLLTTVTRKKKETEMLGEEARELLS 960
ISNENSVNYKNESSAKREEGNFDTLTSSINARANALLLTTVTRKKKETEMLGEEARELLS
Sbjct: 901 ISNENSVNYKNESSAKREEGNFDTLTSSINARANALLLTTVTRKKKETEMLGEEARELLS 960
Query: 961 HFNHQNMDALLKVTRNTLEAIRKRIHSSHTINFRDSNSASNMKQNSLPIFRASVTLAIPN 1020
HFNHQNMDALLKVTRNTLEAIRKRIHSSHTINFRDSNSASNMKQNSLPIFRASVTLAIPN
Sbjct: 961 HFNHQNMDALLKVTRNTLEAIRKRIHSSHTINFRDSNSASNMKQNSLPIFRASVTLAIPN 1020
Query: 1021 IVMAPALEDVQQTLNKAVECIISVPKGVRQWSSELLSKKKIQERKMAALQSNEDSDSDVE 1080
IVMAPALEDVQQTLNKAVECIISVPKGVRQWSSELLSKKKIQERKMAALQSNEDSDSDVE
Sbjct: 1021 IVMAPALEDVQQTLNKAVECIISVPKGVRQWSSELLSKKKIQERKMAALQSNEDSDSDVE 1080
Query: 1081 MGENELQDTLEIASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTIINSTKKEVITSMDC 1140
MGENELQDTLEIASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTIINSTKKEVITSMDC
Sbjct: 1081 MGENELQDTLEIASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTIINSTKKEVITSMDC 1140
Query: 1141 FKRYNHIWQKGKEEAIKTFITQSPLLSEFESQILYFQNLEQEINAEPEYVCVGSIALYTA 1200
FKRYNHIWQKGKEEAIKTFITQSPLLSEFESQILYFQNLEQEINAEPEYVCVGSIALYTA
Sbjct: 1141 FKRYNHIWQKGKEEAIKTFITQSPLLSEFESQILYFQNLEQEINAEPEYVCVGSIALYTA 1200
Query: 1201 DLKFALTAETKAWMVVIGRHCNKKYRSEMENIFMLIEEFNKKLNRPIKDLDDIRIAMAAL 1260
DLKFALTAETKAWMVVIGRHCNKKYRSEMENIFMLIEEFNKKLNRPIKDLDDIRIAMAAL
Sbjct: 1201 DLKFALTAETKAWMVVIGRHCNKKYRSEMENIFMLIEEFNKKLNRPIKDLDDIRIAMAAL 1260
Query: 1261 KEIREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKVDTLHYAWEKLLARAGEVQNKL 1320
KEIREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKVDTLHYAWEKLLARAGEVQNKL
Sbjct: 1261 KEIREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKVDTLHYAWEKLLARAGEVQNKL 1320
Query: 1321 VSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMASGLKPQEASDRLIMFQNQFDNIYR 1380
VSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMASGLKPQEASDRLIMFQNQFDNIYR
Sbjct: 1321 VSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMASGLKPQEASDRLIMFQNQFDNIYR 1380
Query: 1381 KYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIYTLYNSVIETVNSYYDILWSEVNIE 1440
KYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIYTLYNSVIETVNSYYDILWSEVNIE
Sbjct: 1381 KYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIYTLYNSVIETVNSYYDILWSEVNIE 1440
Query: 1441 KINNELLEFQNRCRKLPRALKDWQAFLDLKKIIDDFSECCPLLEYMASKAMMERHWERIT 1500
KINNELLEFQNRCRKLPRALKDWQAFLDLKKIIDDFSECCPLLEYMASKAMMERHWERIT
Sbjct: 1441 KINNELLEFQNRCRKLPRALKDWQAFLDLKKIIDDFSECCPLLEYMASKAMMERHWERIT 1500
Query: 1501 TLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTF 1560
TLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTF
Sbjct: 1501 TLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTF 1560
Query: 1561 TFGSFKTRGELLLRGDSTSEIIANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTD 1620
TFGSFKTRGELLLRGDSTSEIIANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTD
Sbjct: 1561 TFGSFKTRGELLLRGDSTSEIIANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTD 1620
Query: 1621 IIESWMTVQNLWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCV 1680
IIESWMTVQNLWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCV
Sbjct: 1621 IIESWMTVQNLWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCV 1680
Query: 1681 GDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQA 1740
GDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQA
Sbjct: 1681 GDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQA 1740
Query: 1741 HLLNVFDNIKSVKFHEKIYDRILSISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSSL 1800
HLLNVFDNIKSVKFHEKIYDRILSISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSSL
Sbjct: 1741 HLLNVFDNIKSVKFHEKIYDRILSISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSSL 1800
Query: 1801 HLVIRQAAANIQETGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEALRNAKFDKKIMQKTN 1860
HLVIRQAAANIQETGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEALRNAKFDKKIMQKTN
Sbjct: 1801 HLVIRQAAANIQETGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEALRNAKFDKKIMQKTN 1860
Query: 1861 QAFLELLNTLIDVTTRDLSSTERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQC 1920
QAFLELLNTLIDVTTRDLSSTERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQC
Sbjct: 1861 QAFLELLNTLIDVTTRDLSSTERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQC 1920
Query: 1921 RFYFNEDSDKMMIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAG 1980
RFYFNEDSDKMMIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAG
Sbjct: 1921 RFYFNEDSDKMMIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAG 1980
Query: 1981 PAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLP 2040
PAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLP
Sbjct: 1981 PAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLP 2040
Query: 2041 VLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKIN 2100
VLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKIN
Sbjct: 2041 VLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKIN 2100
Query: 2101 FRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILS 2160
FRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILS
Sbjct: 2101 FRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILS 2160
Query: 2161 VLRTLGAAKRANPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYP 2220
VLRTLGAAKRANPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYP
Sbjct: 2161 VLRTLGAAKRANPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYP 2220
Query: 2221 ELEAAISRQVEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMT 2280
ELEAAISRQVEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMT
Sbjct: 2221 ELEAAISRQVEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMT 2280
Query: 2281 DCGKPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGP 2340
DCGKPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGP
Sbjct: 2281 DCGKPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGP 2340
Query: 2341 VDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSS 2400
VDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSS
Sbjct: 2341 VDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSS 2400
Query: 2401 SILDWSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQNLEYKMEVLEAFVITQSIN 2460
SILDWSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQNLEYKMEVLEAFVITQSIN
Sbjct: 2401 SILDWSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQNLEYKMEVLEAFVITQSIN 2460
Query: 2461 MLQGLIPLKEQGGEVSQAHLGRLFVFALLWSAGAALELDGRRRLELWLRSRPTGTLELPP 2520
MLQGLIPLKEQGGEVSQAHLGRLFVFALLWSAGAALELDGRRRLELWLRSRPTGTLELPP
Sbjct: 2461 MLQGLIPLKEQGGEVSQAHLGRLFVFALLWSAGAALELDGRRRLELWLRSRPTGTLELPP 2520
Query: 2521 PAGPGDTAFDYYVAPDGTWTHWNTRTQEYLYPSDTTPEYGSILVPNVDNVRTDFLIQTIA 2580
PAGPGDTAFDYYVAPDGTWTHWNTRTQEYLYPSDTTPEYGSILVPNVDNVRTDFLIQTIA
Sbjct: 2521 PAGPGDTAFDYYVAPDGTWTHWNTRTQEYLYPSDTTPEYGSILVPNVDNVRTDFLIQTIA 2580
Query: 2581 KQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRM 2640
KQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRM
Sbjct: 2581 KQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRM 2640
Query: 2641 GTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDI 2700
GTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDI
Sbjct: 2641 GTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDI 2700
Query: 2701 QFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVR 2760
QFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVR
Sbjct: 2701 QFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVR 2760
Query: 2761 DSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLK 2820
DSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLK
Sbjct: 2761 DSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLK 2820
Query: 2821 LWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGEEKKLLVDCGIDTYFVDFLRDAPE 2880
LWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGEEKKLLVDCGIDTYFVDFLRDAPE
Sbjct: 2821 LWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGEEKKLLVDCGIDTYFVDFLRDAPE 2880
Query: 2881 AAGETSEEADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVK 2940
AAGETSEEADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVK
Sbjct: 2881 AAGETSEEADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVK 2940
Query: 2941 ISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYR 3000
ISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYR
Sbjct: 2941 ISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYR 3000
Query: 3001 TAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEF 3060
TAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEF
Sbjct: 3001 TAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEF 3060
Query: 3061 PRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKD 3120
PRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKD
Sbjct: 3061 PRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKD 3120
Query: 3121 ALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLS 3180
ALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLS
Sbjct: 3121 ALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLS 3180
Query: 3181 FIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADM 3240
FIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADM
Sbjct: 3181 FIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADM 3240
Query: 3241 VLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQT 3300
VLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQT
Sbjct: 3241 VLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQT 3300
Query: 3301 IRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLMTAG 3360
IRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLMTAG
Sbjct: 3301 IRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLMTAG 3360
Query: 3361 NFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSIN 3420
NFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSIN
Sbjct: 3361 NFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSIN 3420
Query: 3421 KEVLPLKANLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAE 3480
KEVLPLKANLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAE
Sbjct: 3421 KEVLPLKANLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAE 3480
Query: 3481 RCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRD 3540
RCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRD
Sbjct: 3481 RCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRD 3540
Query: 3541 LLLNDWRKEMKARKIPFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRY 3600
LLLNDWRKEMKARKIPFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRY
Sbjct: 3541 LLLNDWRKEMKARKIPFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRY 3600
Query: 3601 PLLIDPQTQGKIWIKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPAL 3660
PLLIDPQTQGKIWIKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPAL
Sbjct: 3601 PLLIDPQTQGKIWIKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPAL 3660
Query: 3661 DNVLERNFIKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTM 3720
DNVLERNFIKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTM
Sbjct: 3661 DNVLERNFIKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTM 3720
Query: 3721 KGLEDQLLGRVILTEKQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDES 3780
KGLEDQLLGRVILTEKQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDES
Sbjct: 3721 KGLEDQLLGRVILTEKQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDES 3780
Query: 3781 LIVVLSNTKRTAEEVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMY 3840
LIVVLSNTKRTAEEVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMY
Sbjct: 3781 LIVVLSNTKRTAEEVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMY 3840
Query: 3841 QTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLT 3900
QTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLT
Sbjct: 3841 QTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLT 3900
Query: 3901 LKIDIQRNRVKHEEFLTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLD 3960
LKIDIQRNRVKHEEFLTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLD
Sbjct: 3901 LKIDIQRNRVKHEEFLTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLD 3960
Query: 3961 QISRNEKMWKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSM 4020
QISRNEKMWKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSM
Sbjct: 3961 QISRNEKMWKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSM 4020
Query: 4021 GEKYAEGVILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKIETRYVSMGQGQE 4080
GEKYAEGVILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKIETRYVSMGQGQE
Sbjct: 4021 GEKYAEGVILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKIETRYVSMGQGQE 4080
Query: 4081 VHARKLLQQTMANGGWALLQNCHLGLDFMDELMDIIIETELVHDAFRLWMTTEAHKQFPI 4140
VHARKLLQQTMANGGWALLQNCHLGLDFMDELMDIIIETELVHDAFRLWMTTEAHKQFPI
Sbjct: 4081 VHARKLLQQTMANGGWALLQNCHLGLDFMDELMDIIIETELVHDAFRLWMTTEAHKQFPI 4140
Query: 4141 TLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSGSQWKPMLYAVAFLHSTVQERRK 4200
TLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSGSQWKPMLYAVAFLHSTVQERRK
Sbjct: 4141 TLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSGSQWKPMLYAVAFLHSTVQERRK 4200
Query: 4201 FGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDDYD 4260
FGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDDYD
Sbjct: 4201 FGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDDYD 4260
Query: 4261 KRLLNTFAKVWFSENMFGPDFSFYQGYNIPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNA 4320
KRLLNTFAKVWFSENMFGPDFSFYQGYNIPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNA
Sbjct: 4261 KRLLNTFAKVWFSENMFGPDFSFYQGYNIPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNA 4320
Query: 4321 DITYQSKLAKDVLDTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDYVPFEVKERL 4380
DITYQSKLAKDVLDTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDYVPFEVKERL
Sbjct: 4321 DITYQSKLAKDVLDTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDYVPFEVKERL 4380
Query: 4381 QKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDARI 4440
QKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDARI
Sbjct: 4381 QKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDARI 4440
Query: 4441 PAWWKKASWISSTLGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQGFLTAMRQEIT 4500
PAWWKKASWISSTLGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQGFLTAMRQEIT
Sbjct: 4441 PAWWKKASWISSTLGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQGFLTAMRQEIT 4500
Query: 4501 RANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVL 4560
RANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVL
Sbjct: 4501 RANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVL 4560
Query: 4561 FELMPVIRIYAENNTLRDPRFYSCPIYKKPVRTDLNYIAAVDLRTAQTPEHWVLRGVALL 4620
FELMPVIRIYAENNTLRDPRFYSCPIYKKPVRTDLNYIAAVDLRTAQTPEHWVLRGVALL
Sbjct: 4561 FELMPVIRIYAENNTLRDPRFYSCPIYKKPVRTDLNYIAAVDLRTAQTPEHWVLRGVALL 4620
Query: 4621 CDVK 4624
CDVK
Sbjct: 4621 CDVK 4624
>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
Length = 4490
Score = 5675 bits (14723), Expect = 0.0
Identities = 2804/4521 (62%), Positives = 3492/4521 (77%), Gaps = 41/4521 (0%)
Query: 112 KVFVTEGNDVALTGVCVFFIRTDPSKAITPDNIHQEVSFNMLDAADGGLLNSVRRLLSDI 171
K+++ L G+C+FF+R AI I +E F +LDA+ G LLN +R +L++I
Sbjct: 3 KLYIDNAAPDKLKGLCIFFVRCRNDVAINVKTIQEEALFTVLDASKG-LLNGIRDMLANI 61
Query: 172 FIPALRATSHGWGELEGLQDAANIRQEFLSSLEGFVNVLSGAQESLKEKVNLRKCDILEL 231
F+PA+ AT++ WG L + + + F ++ +++ L GA+ S++ V L+ D +
Sbjct: 62 FLPAVLATNN-WGALNQSKQGESEKHIFTETINRYLSFLDGARISIEGTVKLKTIDNVNF 120
Query: 232 KTLKEPTDYLTLANNPETLGKIEDCMKVWIKQTEQVLAENNQLLKEADDVGPRAELEHWK 291
L + A+N ET+ ++E+ + VW KQ EQVL E+ Q+ KEA D GP ELEHWK
Sbjct: 121 SKLHTFEEVTAAASNSETVHQLEEVLMVWYKQIEQVLIESEQMRKEAGDSGPLTELEHWK 180
Query: 292 KRLSKFNYLLEQLKSPDVKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTL 351
+ +KFNY++EQ+K P KAV+ VL A SKLLK WR++D RITD NE+KDNV+YLYTL
Sbjct: 181 RMSAKFNYIIEQIKGPSCKAVINVLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTL 240
Query: 352 EKCCDPLYSSDPLSMMDAIPTLINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAY 411
EK C PLY+ D +SM I LINAI+MI+ +S YYNTSE++TSLF+KVTNQ+++ACKAY
Sbjct: 241 EKVCQPLYNHDLVSMAHGIQNLINAIRMIHGVSRYYNTSERMTSLFIKVTNQMVTACKAY 300
Query: 412 ITNNGTASIWNQPQDVVEEKILSAIKLKQEYQLCFHKTKQKLKQNPNAKQFDFSEMYIFG 471
IT+ G +W+Q VV +KI I L +EYQ FHKT++ + ++ K F+ SEMYIFG
Sbjct: 301 ITDGGLNHVWDQETPVVLKKIQDCIFLFKEYQASFHKTRKLISESSGEKSFEVSEMYIFG 360
Query: 472 KFETFHRRLAKIIDIFTTLKTYSVLQDSTIEGLEDMATKYQGIVATIKKKEYNFLDQRKM 531
KFE F +RL KI ++ T ++TYS L +STIEG++ MA K++ I +KKK+Y+ LD R+
Sbjct: 361 KFEAFCKRLEKITEMITVVQTYSTLSNSTIEGIDIMAIKFRNIYQGVKKKQYDILDPRRT 420
Query: 532 DFDQDYEEFCKQTNDLHNELRKFMDVTFAKIQNTNQALRMLKKFERLNIPNLGIDDKYQL 591
+FD D+ +F + N L +++ FM+ +F KI ++ QAL++L++F++LNIP LG++ + +
Sbjct: 421 EFDTDFLDFMTKINGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLNIPCLGLEINHTI 480
Query: 592 --ILENYGADIDMISKLYTKQKYDPPLARNQPPIAGKILWARQLFHRIQQPMQLFQQHPA 649
IL+ Y A++D KLY QK DPPLARN PPIAGKILW RQL+ RI +P+ F ++
Sbjct: 481 ERILQYYVAELDATKKLYHSQKDDPPLARNMPPIAGKILWVRQLYRRISEPINYFFKNSD 540
Query: 650 VLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWLRQIEEIHVGLEASLLVKAPGTGELFVN 709
+LS+ + K +IR YN+++ VL+EFEV++H AW+R+I ++H L+A+L V+ P TG+L VN
Sbjct: 541 ILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWIREISQLHYALQATLFVRHPETGKLLVN 600
Query: 710 FDPQILILFRETECMAQMGLEVSPLATSLFQKRDRYKRNFSNMKMMLAEYQRVKSKIPAA 769
FDP+IL + RET+CM +M L+V A L + + K + ++ +L Y + ++P+
Sbjct: 601 FDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPSV 660
Query: 770 IEQLIVPHLAKVDEALQPGLAALTWTSLNIEAYLENTFAKIKDLELLLDRVNDLIEFRID 829
L+ P + KV+ L+ GL LTW+SL +E++ + + LL +++DL E ID
Sbjct: 661 FVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQEVELVLDMFNQLLKKISDLCEMHID 720
Query: 830 AILEEMSSTPLCQLPQEEPLTCEEFLQMTKDLCVNGAQILHFKSSLVEEAVNELVNMLLD 889
+L+E++ T L LP+ E+ L + + A IL+ KS VEEAV EL+++
Sbjct: 721 TVLKEIAKTVLISLPESGATKVEDMLTLNETYTKEWADILNHKSKHVEEAVRELISIF-- 778
Query: 890 VEVLSEEESEKISNENSVNYKNESSAKREEGNFDTLTSS-INARANALLLTTVTRKKKET 948
E+I + S +R+ F + T N A ++ KE
Sbjct: 779 ---------EQIYEVKYTGKVGKQSEQRKHVVFGSETGEGENNDYEANIVNEFDTHDKED 829
Query: 949 EMLGEEARELLSHFNHQNMDALLKVTRNTLEAIRKRIHSSHTINFRDSNSASNMKQNSLP 1008
E +E +E+ + F+HQ +D+L K TR +L+ +++RI F S ++ +
Sbjct: 830 EFK-KECKEVFAFFSHQLLDSLQKATRLSLDTMKRRI-------FVASLYGRKQSEDIIS 881
Query: 1009 IFRASVTLAIPNIVMAPALEDVQQTLNKAVECIISVPKGVRQWSSELLSK-KKIQERKMA 1067
++ V LAIPN+VM P+L+D+QQ +N+ ++ + V +GV W + + K +
Sbjct: 882 FIKSEVHLAIPNVVMIPSLDDIQQAINRMIQLTLEVSRGVAHWGQQQIRPIKSVIPSPTT 941
Query: 1068 ALQSNEDSDSDVEMGENELQDTLEIASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTII 1127
+++++ ++ E ++ + + KN+Y V+E+K+I KLV +LS+ +
Sbjct: 942 TDVTHQNTGKLLKKEERSFEEAIPARKL--------KNFYPGVAEHKDISKLVLLLSSSV 993
Query: 1128 NSTKKEVITSMDCFKRYNHIWQKGKEEAIKTFITQSPLLSEFESQILYFQNLEQEINAEP 1187
NS +K ++ F++Y +W + ++ +K F+ +P L+E S+IL++ EQEI+
Sbjct: 994 NSLRKAAHEALQDFQKYKTLWTEDRDVKVKEFLANNPSLTEIRSEILHYATFEQEIDELK 1053
Query: 1188 EYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIFMLIEEFNKKLNRPI 1247
+ VG++ L+T +K AL+ E KAW +++ R+ N++Y+ +M + I E+ KKL+RPI
Sbjct: 1054 PIIVVGALELHTEPMKLALSIEAKAWKMLLCRYLNEEYKKKMSYMIAFINEYLKKLSRPI 1113
Query: 1248 KDLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKVDTLHYAWE 1307
+DLDD+R AM AL IR+ +I +D +GPIEE+YA+LNR+ + + +EE + VDTL Y++
Sbjct: 1114 RDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSFN 1173
Query: 1308 KLLARAGEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMASGLKPQEASDR 1367
KL ++A VQ LV +QP FK L+ +VEVF +D F Y+L GPM + PQEAS+R
Sbjct: 1174 KLQSKAVSVQEDLVQVQPKFKSNLLESVEVFREDVINFAEAYELEGPMVPNIPPQEASNR 1233
Query: 1368 LIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIYTLYNSVIETVN 1427
L +FQ FD+++RK++TY+ GE+LFGLP T Y L + +K+LNLLQK+Y LY++V+ +++
Sbjct: 1234 LQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSIS 1293
Query: 1428 SYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKKIIDDFSECCPLLEYMA 1487
YY+ILW +V+IEKIN ELLEFQNRCRKLP+ LKDWQAFLDLKK IDDFSE CPLLE M
Sbjct: 1294 GYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMT 1353
Query: 1488 SKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQK 1547
+KAM +RHW+RI+ LTG DV ++SF LRNIMEAPLLK+K++IEDICISA+KE+DIE K
Sbjct: 1354 NKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAK 1413
Query: 1548 LKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEIIANMEDSLMLLGSLLSNRYNMPFKAQ 1607
L QVI W N+ +F +FK +GELLL+G + EII MEDSLM+LGSLLSNRYN PFK
Sbjct: 1414 LTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKN 1473
Query: 1608 IQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMT 1667
IQ WV LS S+DIIE W+ VQNLW+YLEAVFVGGDIAKQLP+EAKRF NIDKSW+KIM
Sbjct: 1474 IQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQ 1533
Query: 1668 RAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLE 1727
RAHE P+V+ CCVGDET+GQLLPHL +QLE+CQKSLTGYLEKKRL FPRFFFVSDP LLE
Sbjct: 1534 RAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLE 1593
Query: 1728 ILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDRILSISSQEGETIELDKPVMAEGNVEV 1787
ILGQASDSHTIQ HL V DNI V FH K YDRI+++ S+EGE I LD VMA+G VE+
Sbjct: 1594 ILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRIMAVISREGEKIVLDNSVMAKGPVEI 1653
Query: 1788 WLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEALR 1847
WL LL+ SSLH +IR A I ++GFQL FLS FPAQVGLLGIQM+WT DSEEALR
Sbjct: 1654 WLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGIQMLWTHDSEEALR 1713
Query: 1848 NAKFDKKIMQKTNQAFLELLNTLIDVTTRDLSSTERVKYETLITIHVHQRDIFDDLCHMH 1907
NAK D+KIMQ TNQ FL++LNTLI TT DLS +RVK+ETLITIHVHQRDIFDDL MH
Sbjct: 1714 NAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIHVHQRDIFDDLVKMH 1773
Query: 1908 IKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLA 1967
IKSP DFEWLKQ RFYF ED D+ ++ ITDV FIYQNEFLGCTDRLVITPLTDRCYITLA
Sbjct: 1774 IKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFLGCTDRLVITPLTDRCYITLA 1833
Query: 1968 QALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGS 2027
QALGM+MGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGS
Sbjct: 1834 QALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGS 1893
Query: 2028 WGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGY 2087
WGCFDEFNRI+LPVLSVAAQQI I+LT +KE KK FIF+DGD V +NPEFG+FLTMNPGY
Sbjct: 1894 WGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSDGDCVDLNPEFGIFLTMNPGY 1953
Query: 2088 AGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSK 2147
AGRQELPENLKI FR+VAMMVPDRQII+RVKLASCGF++NV+LA+KF+ LYKLCEEQL+K
Sbjct: 1954 AGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLENVILAQKFYVLYKLCEEQLTK 2013
Query: 2148 QVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIED 2207
QVHYDFGLRNILSVLRTLG+ KRA P D+E +IVMR LRDMNLSKL+DEDEPLFLSLI D
Sbjct: 2014 QVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRDMNLSKLVDEDEPLFLSLIND 2073
Query: 2208 LFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAG 2267
LFP + LD Y EL+ A++ QV+ GLINHPPW LK++QL+ET VRHG+MTLGPSG+G
Sbjct: 2074 LFPGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQLYETSLVRHGLMTLGPSGSG 2133
Query: 2268 KTTCIHTLMRAMTDCGKPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLRA 2327
KTT I LM+A T+CG+PHREMRMNPKAITAPQMFGRLD ATNDWTDGIFSTLWRKTL+A
Sbjct: 2134 KTTVITILMKAQTECGRPHREMRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKA 2193
Query: 2328 KKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASP 2387
KKGE+I++ILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAP+CK++FE HNI+NASP
Sbjct: 2194 KKGENIFLILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASP 2253
Query: 2388 ATVSRNGMVFMSSSILDWSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQNLEYKM 2447
ATVSR GMV++SSS L W PIL+ +LKKR+ QEA + LY + F D Y + NL KM
Sbjct: 2254 ATVSRMGMVYISSSALSWRPILQAWLKKRTAQEAAVFLTLYEKVFEDTYTYMKLNLNPKM 2313
Query: 2448 EVLEAFVITQSINMLQGLIPLKEQGGEVSQAHLGRLFVFALLWSAGAALELDGRRRLELW 2507
++LE I QS+N+L+GLIP KE+GG HL +LFVF L+WS GA LEL+ R +LE +
Sbjct: 2314 QLLECNYIVQSLNLLEGLIPSKEEGGVSCVEHLHKLFVFGLMWSLGALLELESREKLEAF 2373
Query: 2508 LRSRPTGTLELPP-PAGPGDTAFDYYVAPDGTWTHWNTRTQEYLYPSDTTPEYGSILVPN 2566
LR + L+LP P G T +++YV G W HWN + Q Y YP+D+ PEY SILVPN
Sbjct: 2374 LRQHES-KLDLPEIPKGSNQTMYEFYVTDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPN 2432
Query: 2567 VDNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPL 2626
VDN+RT+FLI TIAKQ KAVLL GEQGTAKTV++K ++ KYDPE + KSLNFSSAT P+
Sbjct: 2433 VDNIRTNFLIDTIAKQHKAVLLTGEQGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEPM 2492
Query: 2627 MFQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFY 2686
MFQRTIESYVDKR+G+TYGPP G+KMTVFIDD+NMP+INEWGDQ+TNEIVRQ+ME G Y
Sbjct: 2493 MFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMY 2552
Query: 2687 NLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGV 2746
+L+KPG+FT+IVD+Q +AAMIHPGGGRNDIPQRLKRQF++FNCTLPS AS+DKIFG+IG
Sbjct: 2553 SLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGC 2612
Query: 2747 GHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLN 2806
G++ R F ++ + + LV + R LWQ TK+KMLPTP+KFHY+FNLRDLSR+WQGML
Sbjct: 2613 GYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLT 2672
Query: 2807 TTSEVIKEPNDLLKLWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGEEKKLLVDCG 2866
+E LL L+KHEC RVIADRF D WF+ L VEE G + C
Sbjct: 2673 IKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSD---AASCI 2729
Query: 2867 I-DTYFVDFLRDAPEAAGETSEEADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAG 2925
+ + YFVDFLR+ PE G+ E++ E PKIYE + SF L E+L + + +NE IRG
Sbjct: 2730 LPEPYFVDFLREMPEPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTS 2789
Query: 2926 MDMVFFADAMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRS 2985
+D+VFF DAM HL+KISR+IRT GNALLVGVGGSGKQSL+RLASFIAGY FQITLTRS
Sbjct: 2790 LDLVFFKDAMTHLIKISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRS 2849
Query: 2986 YNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEI 3045
YN +NL +DLK LY+ AG GKGITFIFTD+EIKDE+FLEY+NN+LSSGE+SNLFARDE+
Sbjct: 2850 YNVTNLTDDLKALYKVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEM 2909
Query: 3046 DEINSDLASVMKKEFPRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPAL 3105
DEI L SVMK+E PR PT +NL++YF+SR R+NLH+VLCFSPVGEKFR R+LKFP L
Sbjct: 2910 DEITQGLISVMKRELPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGL 2969
Query: 3106 ISGCTIDWFSRWPKDALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQ 3165
ISGCT+DWFSRWP++AL+AV+ +FL+ Y+I CS EIK++VV+ MG F D V+E C YFQ
Sbjct: 2970 ISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQ 3029
Query: 3166 RFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELE 3225
R+RR HVTPKSYLSFI GYK IY EK + A RMN GL+KL EASESVA LS++L
Sbjct: 3030 RYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQDLA 3089
Query: 3226 AKEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLE 3285
KEKEL VA+ KAD VL EVT+ AQA+ K+K EVQ+VKD+AQ IVD I +K AE KLE
Sbjct: 3090 VKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLE 3149
Query: 3286 AAKPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSC 3345
AAKPALEEAEAAL TI+P+DIATVR L +PPHLIMRIMDCVLLLFQ+K+ V +D EKSC
Sbjct: 3150 AAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSC 3209
Query: 3346 TMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAG 3405
PSW ESLKLM+A FL +LQQFPKDTINEE +E L PYF M DY E+AK+VCGNVAG
Sbjct: 3210 CKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVCGNVAG 3269
Query: 3406 LCSWTKAMASFFSINKEVLPLKANLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEY 3465
L SWT AMA F+ IN+EVLPLKANL QE R +A +L KAQA LD+KQAELD VQA++
Sbjct: 3270 LLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKF 3329
Query: 3466 EQAMTEKQTLLEDAERCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLAT 3525
+ AM EK LL DA+ CR KMQ ASTLI GL+GEK RWT+QS+EF AQ RLVGD+LL T
Sbjct: 3330 DAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCT 3389
Query: 3526 AFLSYSGPFNQEFRDLLLND-WRKEMKARKIPFGKNLNLSEMLIDAPTISEWNLQGLPND 3584
FLSY GPFNQ FR+ LL D W E++ARKIPF +NLNL ML+D PTI EW LQGLP D
Sbjct: 3390 GFLSYLGPFNQIFRNYLLKDQWEMELRARKIPFTENLNLISMLVDPPTIGEWGLQGLPGD 3449
Query: 3585 DLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESRNELQITSLNHKYFRNHLEDSLSLG 3644
DLSIQNGIIVTKA+RYPLLIDPQTQGK WIK+KE N+LQ+TSLNHKYFR HLEDSLSLG
Sbjct: 3450 DLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLG 3509
Query: 3645 RPLLIEDVGEELDPALDNVLERNFIKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPAYT 3704
RPLLIED+ EELDPALDNVLE+NFIK+G+TFKVKVGDKE D++D F+LYITTKLPNPA+T
Sbjct: 3510 RPLLIEDIHEELDPALDNVLEKNFIKSGTTFKVKVGDKECDIMDTFKLYITTKLPNPAFT 3569
Query: 3705 PEISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEKERTHLMEDVTANKRRMKELEDNL 3764
PEI+A+TS+IDFTVTMKGLE+QLL RVILTEKQELE ER L+EDVT NKR+MKELEDNL
Sbjct: 3570 PEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNKRKMKELEDNL 3629
Query: 3765 LYRLTSTQGSLVEDESLIVVLSNTKRTAEEVTQKLEISAETEVQINSAREEYRPVATRGS 3824
LY+L++T+GSLV+DESLI VL TK+TA EV++KL ++AETE++IN+A+EE+RP ATRGS
Sbjct: 3630 LYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQEEFRPAATRGS 3689
Query: 3825 ILYFLITEMRLVNEMYQTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVYKYAA 3884
ILYFLITEM +VN MYQTSL QFL LFD S+ARS KSP+ KRI NIIE++TYEV+ Y+
Sbjct: 3690 ILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSV 3749
Query: 3885 RGLYEEHKFLFTLLLTLKIDIQRNRVKHEEFLTLIKGGASLDLKACPPKPSKWILDITWL 3944
RGLYE HKFLF LL+TLKID+QR VKH EF LIKGGA+LDLKACPPKP +WILD+TWL
Sbjct: 3750 RGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKPYRWILDMTWL 3809
Query: 3945 NLVELSKLRQFSDVLDQISRNEKMWKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWC 4004
NLVELSKL QF+++++QISRNEK WK WFDK+ PEEE +P+ Y+ SLD +LLLIRSWC
Sbjct: 3810 NLVELSKLPQFAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLLLIRSWC 3869
Query: 4005 PDRTIAQARKYIVDSMGEKYAEGVILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGK 4064
PDRT+ QARKYI DS+ EKY E VIL+LEKTWEESD RTPLIC LSMGSDPT+ I AL K
Sbjct: 3870 PDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMGSDPTNQIDALAK 3929
Query: 4065 RLKIETRYVSMGQGQEVHARKLLQQTMANGGWALLQNCHLGLDFMDELMDIIIETELVHD 4124
+LK+E R +SMGQGQEVHARKL+Q +M GGW LLQNCHLGL+FM+EL++ +I TE D
Sbjct: 3930 KLKLECRTISMGQGQEVHARKLIQMSMQQGGWVLLQNCHLGLEFMEELLETLITTEASDD 3989
Query: 4125 AFRLWMTTEAHKQFPITLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSGSQWKPM 4184
+FR+W+TTE H +FPITLLQ S+KF N+PPQG+RAGLKRT++G++QDLLD+S+ WKPM
Sbjct: 3990 SFRVWITTEPHDRFPITLLQTSLKFTNEPPQGVRAGLKRTFAGINQDLLDISNLPMWKPM 4049
Query: 4185 LYAVAFLHSTVQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRY 4244
LY VAFLHSTVQERRKFG LGWNIPYEFN ADF+A+VQFIQNHLD+ D+KKGVSW T+RY
Sbjct: 4050 LYTVAFLHSTVQERRKFGPLGWNIPYEFNSADFSASVQFIQNHLDECDIKKGVSWNTVRY 4109
Query: 4245 MIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFGPDFSFYQGYNIPKCSTVDNYLQYIQS 4304
MIGE+QYGGRVTDD+DKRLLN FA+VWFSE MF P F FY GY IP C T+D Y +YIQS
Sbjct: 4110 MIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEPSFCFYTGYKIPLCKTLDQYFEYIQS 4169
Query: 4305 LPAYDSPEVFGLHPNADITYQSKLAKDVLDTILGIQPKDTSGGGDETREAVVARLADDML 4364
LP+ D+PEVFGLHPNADITYQS A VL+TI IQPK++ GG ETREA+V RL++DML
Sbjct: 4170 LPSLDNPEVFGLHPNADITYQSNTASAVLETITNIQPKESGGGVGETREAIVYRLSEDML 4229
Query: 4365 EKLPPDYVPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIM 4424
KLPPDY+P EVK RL KMG MNIFLRQEIDRMQRV+S++RS+L++LKLAI+GTIIM
Sbjct: 4230 SKLPPDYIPHEVKSRLIKMGHLNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIM 4289
Query: 4425 SENLRDALDCMFDARIPAWWKKASWISSTLGFWFTELIERNSQFTSWVFNGRPHCFWMTG 4484
SENLRDALD M+DARIP WK+ SW SSTLGFWFTEL+ERN+QF++W+F GRP+ FWMTG
Sbjct: 4290 SENLRDALDNMYDARIPQLWKRVSWDSSTLGFWFTELLERNAQFSTWIFEGRPNVFWMTG 4349
Query: 4485 FFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAG 4544
FFNPQGFLTAMRQE+TRA+KGWALD + + NEV + K++I++PP EGVY+YGLY++GA
Sbjct: 4350 FFNPQGFLTAMRQEVTRAHKGWALDTVTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAA 4409
Query: 4545 WDKRNMKLIESKPKVLFELMPVIRIYAENNTL-RDPRFYSCPIYKKPVRTDLNYIAAVDL 4603
WD+RN KL+ES PKVLF +PV+ I+A N+T +DP+ Y CPIYKKP RTDL +I V L
Sbjct: 4410 WDRRNGKLMESTPKVLFTQLPVLHIFAINSTAPKDPKLYVCPIYKKPRRTDLTFITVVYL 4469
Query: 4604 RTAQTPEHWVLRGVALLCDVK 4624
RT +P+HW+LRGVALLCD+K
Sbjct: 4470 RTVLSPDHWILRGVALLCDIK 4490
>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
Length = 4471
Score = 2199 bits (5699), Expect = 0.0
Identities = 1268/3674 (34%), Positives = 2036/3674 (55%), Gaps = 133/3674 (3%)
Query: 994 RDSNSASNMKQNSLPIFRASVTLAIPNIVMAPALEDVQQTLNKAVECIISVPKGVRQWSS 1053
++ S +++ ++P+F L P I++ P ++ + V + + K +W
Sbjct: 878 KNLQSFNSLILGNVPLFHTETILTAPEIILHPNTNEIDKMCFHCVRNCVEITKHFVRW-- 935
Query: 1054 ELLSKKKIQERKMAALQSNEDSDSDVEMGENELQDTLEIASVNLPIPVQTKNYYKNVSEN 1113
+ + + GE E E+ +N +Y ++S N
Sbjct: 936 ----------------MNGSCIECPPQKGEEE-----EVVIIN---------FYNDISLN 965
Query: 1114 KEIVKLVSVLSTIINSTKKEVITSMDCFKRYNHIWQKGKEEAIKTFITQSPLLSEFESQI 1173
+I++ ++ ++ ++ + +KRY +W+ K ++ F + P ++ ++
Sbjct: 966 PQIIEQAVMIPQNVHRILINLMKYLQKWKRYRPLWKLDKAIVMEKFAAKKPPCVAYDEKL 1025
Query: 1174 LYFQNLEQEINAEPEYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIF 1233
++ + E+ P I L L + K+W++ +G+ N+ + E+ N+
Sbjct: 1026 QFYSKIAYEVMRHPLIKDEHCIRLQLRHLANTVQENAKSWVISLGKLLNESAKEELYNLH 1085
Query: 1234 MLIEEFNKKLNRPIKDLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAR 1293
+E K L + L+D++ +A + EIR + + ++ + ++E Y + Y L
Sbjct: 1086 EEMEHLAKNLRKIPNTLEDLKFVLATIAEIRSKSLVMELRYRDVQERYRTMAMYNLFPPD 1145
Query: 1294 EEIDKVDTLHYAWEKLLARAGEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNG 1353
E + VD + W L + V++ L ++ +F + + + +F + G
Sbjct: 1146 AEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAKRFYSEG 1205
Query: 1354 PMASGLKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQ 1413
P + G + + L +++ + + E+LF LP T YP+LL+++K+++ L+
Sbjct: 1206 PGSVGDDLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKEMSGLR 1265
Query: 1414 KIYTLYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKKII 1473
IY LY + + LW +N++ + + F RKLPR ++ L+ +
Sbjct: 1266 MIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSVTYYLEAKM 1325
Query: 1474 DDFSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIED 1533
F + PLL + ++A+ +RHW+ + T ++ E+F L N+ L K+ + + +
Sbjct: 1326 KAFKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEM-TETFTLENMFAMELHKHTDVLNE 1384
Query: 1534 ICISAVKERDIEQKLKQVINEWDNKTFTFGSF----KTRGELLLRGDSTSEIIANMEDSL 1589
I +A+KE IE+ +K++++ W+N FT + + RG +L S EII +++D+
Sbjct: 1385 IVTAAIKEVAIEKAVKEILDTWENMKFTVVKYCKGTQERGYIL---GSVDEIIQSLDDNT 1441
Query: 1590 MLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGGDIAKQLP 1649
L S+ +R+ PF + KW + LS ++IE WM VQ W+YLE++F+GGDI QLP
Sbjct: 1442 FNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGGDIRSQLP 1501
Query: 1650 KEAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLEK 1709
+EAK+F NIDK + +IM + P + +CC L L ++ + LE CQKSL YL+
Sbjct: 1502 EEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDL-QNVSEGLEKCQKSLNDYLDS 1560
Query: 1710 KRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFH-----EKIYDRILS 1764
KR FPRFFF+SD LL ILG +SD +Q H++ ++DNI S++F+ EK+ ++S
Sbjct: 1561 KRNAFPRFFFISDDELLSILG-SSDPLCVQEHMIKMYDNIASLRFNDGDSGEKLVSAMIS 1619
Query: 1765 ISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLSS 1824
EGE +E K + AEG VE W+ ++L E + + L+ ++A E ++ +++
Sbjct: 1620 A---EGEVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRV-DWMLL 1675
Query: 1825 FPAQVGLLGIQMIWTRDSEEALRNA-KFDKKIMQKTNQAFLELLNTLIDVTTRDLSSTER 1883
+ V L Q+ WT + E+ A K +K+ M+ + ++ L+ T LS +R
Sbjct: 1676 YQGMVVLAASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDR 1735
Query: 1884 VKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQ 1943
KY T++ I VH RDI D I +F+W Q RFY++ + D++ I F Y
Sbjct: 1736 KKYNTVLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYG 1795
Query: 1944 NEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVV 2003
E++G RLVITPLTDR Y+TL QAL M +GGAPAGPAGTGKTETTKD+ + LG VV
Sbjct: 1796 YEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVV 1855
Query: 2004 FNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSF 2063
NC + MD+R +G+IF GLAQ G+WGCFDEFNRID VLSV + QI I +F
Sbjct: 1856 TNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTF 1915
Query: 2064 IFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCG 2123
F +G ++++ G+F+TMNPGYAGR ELPE++K FR V ++VPD Q I + L S G
Sbjct: 1916 QF-EGQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEG 1974
Query: 2124 FIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMR 2183
F++ LA+K LYKL EQLSKQ HYDFGLR + SVL G KR + E ++MR
Sbjct: 1975 FLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMR 2034
Query: 2184 VLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKL 2243
LRDMNL K + ED PLFL LI DLFP + + YP+ A+ + +EE G P
Sbjct: 2035 ALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVD 2094
Query: 2244 KVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKPHREMRMNPKAITAPQMFG 2303
KV+Q+FET RH M +GP+ GK+ I+TL +A T G + +NPKA++ +++G
Sbjct: 2095 KVVQMFETMLTRHTTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLYILNPKAVSVIELYG 2154
Query: 2304 RLDVATNDWTDGIFSTLWRKTLR-AKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLA 2362
LD T DWTDG+ S ++R+ + K E +I+ DG VDA+W+EN+NSV+DDN+ LTLA
Sbjct: 2155 ILDPTTRDWTDGVLSNIFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLA 2214
Query: 2363 NGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFLKKRSPQEAE 2422
NG+RI + +C ++FE ++ ASPATVSR GMV++ L + P + ++ + P + E
Sbjct: 2215 NGERIRLQAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQ-IPNKVE 2273
Query: 2423 I--LRQLYTESFPDLYRFCIQNLE--YKMEVLEAFVITQSINMLQGLIPLKEQ--GGEVS 2476
L L+ + P L ++ + + E L+ V +NM+ L + + GE+
Sbjct: 2274 QYNLNSLFEKYVPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLEGEIE 2333
Query: 2477 QAHLGRL-FVFALLWSAGAALELDGRRRLELWL-RSRPTGTLELPPP-AGPGD------T 2527
L F+ AL S GA+L DGR + + ++ R T++ A PG+ T
Sbjct: 2334 DLDLLECYFLEALYCSLGASLLEDGRMKFDEYIKRLASLSTVDTEGVWANPGELPGQLPT 2393
Query: 2528 AFDYYVAPD-GTWTHWNTRTQEYLYPSDTTPEYGSILVPNVDNVRTDFLIQTIAKQGKAV 2586
+D++ W W+ EY++ + ++ +ILV VD RT ++++ + K + V
Sbjct: 2394 LYDFHFDNKRNQWVPWSKLVPEYIHAPER--KFINILVHTVDTTRTTWILEQMVKIKQPV 2451
Query: 2587 LLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGP 2646
+ +GE GT+KT + F+ E +++ +NFSS TT + QR +E+ V+KR TYGP
Sbjct: 2452 IFVGESGTSKTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGP 2511
Query: 2647 PAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAM 2706
P GK++ VF+DD+NMP ++E+G Q +++ L+E+ Y+ K SI D+ F+AAM
Sbjct: 2512 PMGKRLLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAM 2571
Query: 2707 IHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKL 2766
GGGRN++ R FS+FN PSE S+ I+ I GH T F E + KL
Sbjct: 2572 GKAGGGRNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKGHTST---FHESIVAVSGKL 2628
Query: 2767 VPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHEC 2826
T L++ + PTP+KFHY+FNLRDLSRV+ G++ T E + ++++W++EC
Sbjct: 2629 TFCTLALYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNEC 2688
Query: 2827 KRVIADRFTVSSDVTWFDKALVSLVEEEFGEEKKLLVDCGIDTYFVDFLRDAPEAAGETS 2886
RV DR +D + + SLV E F ++ +++ +RD P G+
Sbjct: 2689 LRVFHDRLISETDKQLVQQHIGSLVVEHFKDDVEVV------------MRD-PILFGDFQ 2735
Query: 2887 EEADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIR 2946
P+IYE I+ + K L+ YNES M++V F DA+ HL ++ R+IR
Sbjct: 2736 MALHEGEPRIYEDIQDYEAAKALFQEILEEYNES--NTKMNLVLFDDALEHLTRVHRIIR 2793
Query: 2947 TPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQG 3006
+G+ALLVGVGGSGKQSL+RLA+F A F+I L+R Y+ ++ EDLK LY G +
Sbjct: 2794 MDRGHALLVGVGGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIEN 2853
Query: 3007 KGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPT 3066
K + F+FTD + +E FLE +NN+L+SG V LF+ +E + I S + K+ P
Sbjct: 2854 KAMIFLFTDAHVAEEGFLELINNMLTSGIVPALFSEEEKESILSQIGQEALKQGMG--PA 2911
Query: 3067 NENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVS 3126
E++ YF+++ NLHIVL SPVG+ R FP +++ IDWF WP AL AV+
Sbjct: 2912 KESVWQYFVNKSANNLHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVA 2971
Query: 3127 EHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYK 3186
+ FL Y+ E + VV+ + V + Q+ RRS +VTPK+YL FI Y
Sbjct: 2972 KSFL-GYNPMIPAENIENVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYS 3030
Query: 3187 FIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVT 3246
+ EK R++ GL+KLKEA+ + L+++L ++ L + + +L+E+
Sbjct: 3031 KLLDEKTQCNIAQCKRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIA 3090
Query: 3247 MKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDI 3306
+ AE+ K ++ + I+ +KA AE L P LE A+ LQ + SD+
Sbjct: 3091 VNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDV 3150
Query: 3307 ATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLMTAGNFLQNL 3366
+R+ +PP + + +C+L++ K +W+ + +M+ NFL++L
Sbjct: 3151 TEIRSFAKPPKQVQTVCECILIM-------------KGYKELNWKTAKGVMSDPNFLRSL 3197
Query: 3367 QQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPL 3426
+ D+I + ++ + + + E + V G+ + +A+ + + +E+ P
Sbjct: 3198 MEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPK 3257
Query: 3427 KANLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKM 3486
+ + E L ++L++ Q EL Q EL+ + A+YE A+ EKQ L E+AE ++
Sbjct: 3258 REKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRL 3317
Query: 3487 QTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLND- 3545
A LISGL E RW E + +L+GD LL AFLSY G F EFRD ++N
Sbjct: 3318 IAADKLISGLGSENIRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRI 3377
Query: 3546 WRKEMKARKIPFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLID 3605
W+ ++ R+IP + L +L D IS W QGLP D+LS+QNGI+ T+ASR+PL ID
Sbjct: 3378 WQNDILEREIPLSQPFRLESLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCID 3437
Query: 3606 PQTQGKIWIKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLE 3665
PQ Q WIK KE +N L++ S N F LE S+ G P L DV E +DP +DNVLE
Sbjct: 3438 PQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLE 3497
Query: 3666 RNF-IKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLE 3724
+N + G F + +GDKEVD FRLY+ TKL NP Y+P + + +I++TVT+KGLE
Sbjct: 3498 KNIKVSQGRQFII-LGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLE 3556
Query: 3725 DQLLGRVILTEKQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVV 3784
DQLL ++ E++ELE++R HL+++ + NK +K+LED+LL L ++ G+++++ L+
Sbjct: 3557 DQLLSVLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHT 3616
Query: 3785 LSNTKRTAEEVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSL 3844
L TK A EV++KL+++ +T + I+ R+ YRP A RG+IL+F+++EM LVN MYQ SL
Sbjct: 3617 LEETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSL 3676
Query: 3845 RQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKID 3904
FL +F LSL +S+ I KR+ NI++ +T+ +Y + GL+E HK LF+ +T+KI+
Sbjct: 3677 IAFLEVFRLSLKKSLPDSILMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIE 3736
Query: 3905 IQRNRVKHEEFLTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKL--RQFSDVLDQI 3962
RV EE +KG SL+ K+ KP W+ D W +++ LS++ F + D +
Sbjct: 3737 QAEGRVPQEELDFFLKGNISLE-KSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDV 3795
Query: 3963 SRNEKMWKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGE 4022
N+ +W+ W+D ++ E+ P+P YD ++ F++LL++R + DR Y+ +MGE
Sbjct: 3796 ENNQTVWQEWYDLDSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGE 3855
Query: 4023 KYAEGVILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKI---ETRYVSMGQGQ 4079
KY + ++ E +E+S P +P++ +LS GSDP ++ L +R ++++MGQGQ
Sbjct: 3856 KYVQPPMISFEAIFEQSTPHSPIVFILSPGSDPATDLMKLAERSGFGGNRLKFLAMGQGQ 3915
Query: 4080 EVHARKLLQQTMANGGWALLQNCHLGLDFMDELMDIIIETELVHDAFRLWMTTEAHKQFP 4139
E A +LL+ +A G W +LQNCHL + ++ +L + H FRLW+TT+ K FP
Sbjct: 3916 EKVALQLLETAVARGQWLMLQNCHLLVKWLKDLEKSLERITKPHPDFRLWLTTDPTKGFP 3975
Query: 4140 ITLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSGSQWKPMLYAVAFLHSTVQERR 4199
I +LQ S+K +PP GL+ ++ TY +S ++LD +KP++Y +AF H+ VQERR
Sbjct: 3976 IGILQKSLKVVTEPPNGLKLNMRATYFKISHEMLDQCPHPAFKPLVYVLAFFHAVVQERR 4035
Query: 4200 KFGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKG--VSWTTIRYMIGEIQYGGRVTD 4257
KFG +GWN+ Y+FN++DF ++ + +L ++ + W +++Y+IGE+ YGGR D
Sbjct: 4036 KFGKIGWNVYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAID 4095
Query: 4258 DYDKRLLNTFAKVWFSENMFG--PDFSFYQG----YNIPKCSTVDNYLQYIQSLPAYDSP 4311
+D+R+L + + + +F F F++ Y IP + +++ I++LP ++P
Sbjct: 4096 SFDRRILTIYMDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTP 4155
Query: 4312 EVFGLHPNADITYQSKLAKDVLDTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDY 4371
EVFGLHPNA+I Y ++ A+D+ +L +QP+ +R+ + ++A ++ K+P +
Sbjct: 4156 EVFGLHPNAEIGYYTQAARDMWAHLLELQPQTGESSSGISRDDYIGQVAKEIENKMPKVF 4215
Query: 4372 VPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDA 4431
+V++RL P ++ L QE++R +++ + +L EL+ A+ G + MS L D
Sbjct: 4216 DLDQVRKRLGT--GLSPTSVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDV 4273
Query: 4432 LDCMFDARIPAWWKK-ASWISSTLGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQG 4490
+F IP W++ A +LG W + R SQ+ WV P W++G P+
Sbjct: 4274 ARSLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPSVMWLSGLHIPES 4333
Query: 4491 FLTAMRQEITRANKGWALDNMVLCNEVTKWM-KDDISAPPTEGVYVYGLYLEGAGWDKRN 4549
+LTA+ Q R N GW LD L +VTK+ D+++ +G +V GLYLEGA WD
Sbjct: 4334 YLTALVQATCRKN-GWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEK 4392
Query: 4550 MKLIESKPKVLFELMPVIRIY-AENNTLRDPRFYSCPIYKKPVRTD---LNYIAAVDLRT 4605
LI+SKPKVL +P+++I E + L+ + P+Y +R + + + DL T
Sbjct: 4393 GCLIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAMGVGLVFEADLFT 4452
Query: 4606 AQTPEHWVLRGVAL 4619
+ HWVL+GV L
Sbjct: 4453 TRHISHWVLQGVCL 4466
Score = 180 bits (456), Expect = 3e-44
Identities = 164/741 (22%), Positives = 323/741 (43%), Gaps = 110/741 (14%)
Query: 128 VFFIRTDPSKAITPDNIHQEVSFNMLDAADGGLLNS-----VRRLLSDIFIPALRATSHG 182
VFF+R + +AI+ +E M + + G++N+ ++ ++ +F+PAL H
Sbjct: 100 VFFLR-NTKEAISEATDMKEAMEIMPETLEYGIINANVLHFLKNIICQVFLPALSFNQHR 158
Query: 183 WGELEGLQ--DAAN-----------------------IRQEFLSSLEGFVNVLSGAQESL 217
G+ + +N IR EFL +++ F + + + L
Sbjct: 159 TSTTVGVTSGEVSNSSEHESDLPPMPGEAVEYHSIQLIRDEFLMNVQKFASNIQRTMQQL 218
Query: 218 KEKVNLRKCDILELKTLKEPTDYLTLANNPETLGKIEDCMKVWIKQTEQVLAENNQLLKE 277
+ ++ L E+ + + LA +PET+ +E C+ W+ Q A QL K
Sbjct: 219 EGEIKL------EMPIISVEGEVSDLAADPETVDILEQCVINWLNQIST--AVEAQLKKT 270
Query: 278 ADDVGPRAELEHWKKRLSKFNYLLEQLKSPDVKAVLAVLAAAKSKLLKTWREMDIRITDA 337
GP AE+E W++R + + L EQ K P V+ VL V+ + S L+ + + +
Sbjct: 271 PQGKGPLAEIEFWRERNATLSALHEQTKLPIVRKVLDVIKESDSMLVANLQPVFTELFKF 330
Query: 338 TNEAKDNVKYLYTLEKCCDPL-YSSDPLSMMDAIPTLINAIKMIYSISHYYNTSEKITSL 396
EA DNV++L T+E+ + + S ++D IP +++A++M++ IS +YN E++ L
Sbjct: 331 HTEASDNVRFLSTVERYFKNITHGSGFHVVLDTIPAMMSALRMVWIISRHYNKDERMIPL 390
Query: 397 FVKVTNQIIS-ACKAYITNNGTASIWNQPQDVVEEKILSAIKLKQEYQLCFHKTKQKLKQ 455
++ +I C+ +++ + + + K L A + ++ + T+ K++
Sbjct: 391 MERIAWEIAERVCRVV----NLRTLFKENRASAQSKTLEARNTLRLWKKAYFDTRAKIEA 446
Query: 456 NPNAKQFDFSEMYIFGKFETFHRRLAKIIDIFTTLKTYSVLQDSTIEGLEDMATKYQGIV 515
+ +++F +RL + D T+ + L D V
Sbjct: 447 SGREDRWEFDR-----------KRLFERTDYMATI----------CQDLSD--------V 477
Query: 516 ATIKKKEYNFLDQRKMDFDQDYEEFCKQTNDLHNELRKFMDVTFAKIQNTNQALRMLKKF 575
I ++ YN E T D K +D ++ ++
Sbjct: 478 LQILEEFYNIFGP----------ELKAVTGD-----PKRIDDVLCRVDG------LVTPM 516
Query: 576 ERLNIPNLGIDDK--YQLILENYGAD--IDMISKLYTKQKYDPPLARNQPPIAGKILWAR 631
E L I ++ +++ + + ID+I+K++ + +PPL +N PP+AG I W R
Sbjct: 517 ENLTFDPFSIKSSQFWKYVMDEFKIEVLIDIINKIFVQNLENPPLYKNHPPVAGAIYWER 576
Query: 632 QLFHRIQQPMQLFQQHPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWLRQIEEIHVG 691
LF RI+ + FQ+ +L + + + + Y + + + E+E + W+ E++
Sbjct: 577 SLFFRIKHTILRFQEVQEILDSDRGQEVKQKYLEVGRTMKEYEDRKYEQWMEVTEQVLPA 636
Query: 692 L-------EASLLVKAPGT---GELF-VNFDPQILILFRETECMAQMGLEVSPLATSLFQ 740
L ++S+ + P T G +F +NF P + + ET+ + Q+G V LA ++
Sbjct: 637 LMKKSLLTKSSIATEEPSTLERGAVFAINFSPALREIINETKYLEQLGFTVPELARNVAL 696
Query: 741 KRDRYKRNFSNMKMMLAEYQRVKSKIPAAIEQLIVPHLAKVDEALQPGLAALTWTSLNIE 800
+ D++ R + ++ ML Y + + A L+ H ++ + G L W SL I
Sbjct: 697 QEDKFLRYTAGIQRMLDHYHMLIGTLNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIG 756
Query: 801 AYLENTFAKIKDLELLLDRVN 821
Y+ I E L+ +++
Sbjct: 757 DYITGCKQAIGKFESLVHQIH 777
>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
Length = 4427
Score = 2141 bits (5548), Expect = 0.0
Identities = 1249/3580 (34%), Positives = 1978/3580 (55%), Gaps = 139/3580 (3%)
Query: 1100 PVQTKNYYKNVSENKEIVKLVSVLSTIINSTKKEVITSMDCFKRYNHIWQKGKEEAIKTF 1159
P+QT V ++++I K+ + +S+ + + + + + Y IW+ K+ I +
Sbjct: 923 PIQTV-----VEQDEDIKKIQTQISSGMTNNASLLQNYLKTWDMYREIWEINKDSFIHRY 977
Query: 1160 ITQSPLLSEFESQILYFQNLEQEINAEPEYVCVGSIALYTADLKFALTAETKAWMVVIGR 1219
+P +S F + I + + + E + + L + LKF+L W
Sbjct: 978 QRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFAT 1037
Query: 1220 HCNKKYRSEMENIFMLIEEFNKKLNRPIKDLDDIRIAMAALKEIREEQISIDFQVGPIEE 1279
+ + + ++E +K++RP + L+++ +++ + ++ + +++ Q+ PI E
Sbjct: 1038 LLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDALKHDLANVETQIPPIHE 1097
Query: 1280 SYALLNRYGLLIAREEIDKVDTLHYAWEKLLARAGEVQNKLVSLQPSFKKELISAVEVFL 1339
+A+L +Y + + ++ +D+L+ W + + L + FK LI + + F
Sbjct: 1098 QFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHSADDFK 1157
Query: 1340 QDCHQFYLDYDLNGPMASGLKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQY 1399
+ H D++ G S + A D++ + + + + +F +
Sbjct: 1158 KKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLRANLGIFKIEQPPS 1217
Query: 1400 PQLLEIKKQLNLLQKIYTLYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRA 1459
L ++K+L+ LQ+I+ + E N + + + E + R KL +
Sbjct: 1218 KDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLFRRLTKLAKE 1277
Query: 1460 LKD--WQAFLDLKKIIDDFSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLR 1517
KD W+ + I+ F PL+ + + A+ ERHW+++ D +ESF L
Sbjct: 1278 YKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTLE 1337
Query: 1518 NIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDS 1577
I+E + ++ E+I +I SA KE IE L+ + WD +K +G LRG
Sbjct: 1338 QIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLRG-- 1395
Query: 1578 TSEIIANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEA 1637
T E+ +ED+ + L ++ ++R+ F+ + W + LS ++IE +TVQ W+YLE
Sbjct: 1396 TEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLEN 1455
Query: 1638 VFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLE 1697
+F+G DI KQLP E+ F ++ +W IM R ++ + ++ L L+ + LE
Sbjct: 1456 IFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLI-EMNTILE 1514
Query: 1698 ICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHE- 1756
QKSL YLE KR FPRF+F+S+ LLEILGQ+ + +Q HL FDNIK ++ +
Sbjct: 1515 DIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKV 1574
Query: 1757 ---KIYDRILSISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQE 1813
+ + S +GE I+ V EG VE WL + + + +L ++R +++
Sbjct: 1575 GGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRK 1634
Query: 1814 TGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEALRNAK--FDKKIMQKTNQAFLELLNTLI 1871
+ +++ + QV + Q+ WT D + L AK DKKI++ + + +LN
Sbjct: 1635 FLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYS 1694
Query: 1872 DVTTRDLSSTERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKM 1931
+ +L+ R+K L+TI +H RD+ + L + F+WL Q RFY+ +D D
Sbjct: 1695 EAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDC 1754
Query: 1932 MIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTK 1991
+I T+ F Y E+LG + RLVITPLTDRCY+TL AL + GG+P GPAGTGKTET K
Sbjct: 1755 VIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVK 1814
Query: 1992 DMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISI 2051
D+G+ LG YV+V NCS+ +D++ +GR++ GLAQ+G+WGCFDEFNRI++ VLSV A QI
Sbjct: 1815 DLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILC 1874
Query: 2052 ILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDR 2111
IL+ F F DG + + G+F+TMNPGYAGR ELPENLK FR +AM+VPD
Sbjct: 1875 ILSALAAGLTHFHF-DGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDS 1933
Query: 2112 QIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRA 2171
+I + L GF + +LA+K +TLY L +QLS+Q HYDFGLR + S+LR G +R
Sbjct: 1934 TLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRL 1993
Query: 2172 NPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVE 2231
P T+ +++ +RDMN++KL D PLF ++++DLFPNI L Y +L + +++
Sbjct: 1994 QPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIR 2053
Query: 2232 EAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMTD---CGKPH-- 2286
+ GL + P KV QL+ET+ RH M +G +G+GKT L +++ G P+
Sbjct: 2054 DMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFN 2113
Query: 2287 --REMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAI 2344
RE +NPKA++ +++G D++TN+WTDGI S++ R +K + WI+ DGPVD +
Sbjct: 2114 IVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVDTL 2173
Query: 2345 WIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILD 2404
WIEN+NSV+DDNK LTL NG+RI M ++FE ++ ASPATVSR GMV+ + L
Sbjct: 2174 WIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLG 2233
Query: 2405 WSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQNLEYKMEVLEAFVITQSINMLQG 2464
W P ++ +L+KR E E L++++ + + F N + + + E IT S+ L
Sbjct: 2234 WKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGIT-SLCKLYS 2292
Query: 2465 LIPLKEQG-----GEVSQAHLGRLFVFALLWSAGAALELDGRRRLELWLRSRPTGTLELP 2519
+ E G GE + FVF+++WS A+++ +GR+R++ +LR E+
Sbjct: 2293 ALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLR-------EIE 2345
Query: 2520 PPAGPGDTAFDYYVAPD-GTWTHWNTRT-QEYLYPSDTTPEYGSILVPNVDNVRTDFLIQ 2577
DT ++Y+V P +WT + + + + YP + P Y I+VP VD VR ++L+
Sbjct: 2346 GSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNA-PFY-KIMVPTVDTVRYNYLVS 2403
Query: 2578 TIAKQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVD 2637
++ +LL+G GT KT I + + + +N S+ TT Q IES V+
Sbjct: 2404 SLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVE 2463
Query: 2638 KRMGTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSI 2697
KR Y P GK M F+DD+NMP + +G Q E++R ++ +Y+ K I
Sbjct: 2464 KRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQ-TIKYI 2522
Query: 2698 VDIQFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQR--GF 2755
++ +AAM PGGGR I RL+ +F+I N T P+++ + +IFG + Q+ F
Sbjct: 2523 REMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTM-----INQKLQDF 2577
Query: 2756 SEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEP 2815
EEV+ + T ++ + LPTP K HY+FNLRD+S+V+QGML +
Sbjct: 2578 EEEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTK 2637
Query: 2816 NDLLKLWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGEEKKL----LVDCGIDTYF 2871
+ + +LW HEC RV +DR ++D +A + ++ ++ G L L F
Sbjct: 2638 SSITRLWIHECFRVFSDRLVDAADT----EAFMGIISDKLGSFFDLTFHHLCPSKRPPIF 2693
Query: 2872 VDFLRDAPEAAGETSEEADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFF 2931
DFL++ PK+YE + + LK + L YN S M +V F
Sbjct: 2694 GDFLKE----------------PKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLF 2737
Query: 2932 ADAMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNL 2991
+A+ H+ +I RVI P+GN LLVG+GGSG+QSL RLAS I Y +FQI +T+ Y
Sbjct: 2738 REAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEF 2797
Query: 2992 MEDLKVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSD 3051
+D+K LYR AG + K +FIF D +I DESFLE +NN+LSSGEV NL+ DE +EI S
Sbjct: 2798 RDDIKRLYRQAGVELKTTSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSH 2857
Query: 3052 LASVMKKEFPRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTI 3111
+ + E + ++++L Y + RV+ NLHIVLC SP+G+ FRN ++PAL++ TI
Sbjct: 2858 IIDQARVE--QVPESSDSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTI 2915
Query: 3112 DWFSRWPKDALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRST 3171
+WFS WP++AL+ V+E L D+ I ++V Q + VA+ RR
Sbjct: 2916 NWFSEWPQEALLEVAEKCLIGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHN 2975
Query: 3172 HVTPKSYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELE-AKEKE 3230
+VTP YL + GYK + GEK E+ AN++ TGL K+ E E V +S ELE AK+K
Sbjct: 2976 YVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKV 3035
Query: 3231 LQVANDKADMVLKEVTMKAQAAEKVKA--------EVQKVKDRAQAIVDSISKDKAIAEE 3282
+ + ++ V K +A E+ KA V+++K QA+ D+ KD
Sbjct: 3036 AEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIK--CQALADNAQKD------ 3087
Query: 3283 KLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLE 3342
LE A PALEEA AL+++ DI +++ GRPP + +M V++L +
Sbjct: 3088 -LEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGNE--------- 3137
Query: 3343 KSCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGN 3402
P+W E+ + + NF+++L F KD I+++V++ + Y PD+ + RV
Sbjct: 3138 -----PTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDIIGRVSLA 3192
Query: 3403 VAGLCSWTKAMASFFSINKEVLPLKANLVVQENRHLLAMQDLQKAQAELDDKQAE----L 3458
LC W +AM + + + V P + ++ N L +++ Q A AE +K E L
Sbjct: 3193 AKSLCMWVRAMELYGRLYRVVEPKR----IRMNAALAQLREKQAALAEAQEKLREVAEKL 3248
Query: 3459 DVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLV 3518
++++ +Y++ + +K+ L + +E K++ A L+SGLAGEK RW E Q LV
Sbjct: 3249 EMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLV 3308
Query: 3519 GDVLLATAFLSYSGPFNQEFRDLLLND-WRKEMKARKIPFGKNLNLSEMLIDAPTISEWN 3577
GD LLA AFLSY GPF +RD ++N W ++ ++P + + L + + +WN
Sbjct: 3309 GDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWN 3368
Query: 3578 LQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESRNELQITSLNHKYFRNHL 3637
+QGLP+D S +NGIIVT+ +R+ L+IDPQ Q WIKN E L+I L + L
Sbjct: 3369 IQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRIL 3428
Query: 3638 EDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTGSTFKVKVGDKEVDVLDGFRLYITTK 3697
E ++ G P+L+++V E LDP L+ +L ++ + G +++GDKEV+ FR YITTK
Sbjct: 3429 EHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITTK 3488
Query: 3698 LPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEKERTHLMEDVTANKRRM 3757
L NP Y+PE SA+T+I++F V +GLE QLLG V+ E+ ELE+++ L+ ++ A KR++
Sbjct: 3489 LSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKL 3548
Query: 3758 KELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEVTQKLEISAETEVQINSAREEYR 3817
KELED +L L GSL++D L+ L +K TA EVT++LE S TE+ + ARE YR
Sbjct: 3549 KELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAREAYR 3608
Query: 3818 PVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTY 3877
P A R SIL+F++ +M ++ MYQ SL ++ LF LS+ +S +S RI + ++ TY
Sbjct: 3609 PCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTY 3668
Query: 3878 EVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEFLTLIKGGASLDLKACPPKP-SK 3936
VY+Y R L+E HK LF+ + KI ++ +E+ ++GG LD + P S
Sbjct: 3669 AVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSS 3728
Query: 3937 WILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIWFDKENPEEEPLPNAYDKSLDCFRR 3996
W+ D W N+ EL KL F +++ + + W +W+ PE+ LP ++ + + +R
Sbjct: 3729 WLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNEMQR 3788
Query: 3997 LLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLEKTWEESDPRTPLICLLSMGSDPT 4056
+L++RS DR +I+ ++G ++ E +L+++ E+S PR+PL+ +LS G DPT
Sbjct: 3789 MLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPT 3848
Query: 4057 DSIIALGKRLKIETRY--VSMGQGQEVHARKLLQQTMANGGWALLQNCHLGLDFMDELMD 4114
+++ L + + + R+ +S+GQGQ A +LL++ + G W L NCHL L +M L
Sbjct: 3849 SALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDK 3908
Query: 4115 II--IETELVHDAFRLWMTTEAHKQFPITLLQMSIKFANDPPQGLRAGLKRTYSGVSQDL 4172
++ ++ E H +FRLW+++ H FPI++LQ+SIK +PP+GL+A + R Y +S+
Sbjct: 3909 LVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLMSEPQ 3968
Query: 4173 LD-VSSGSQWKPMLYAVAFLHSTVQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDDM 4231
S +++K +L+++ F HS + ER+KF LGWNI Y FN +DF + + +LD+
Sbjct: 3969 FSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEY 4028
Query: 4232 DVKKGVSWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFGPDF---SFYQGYN 4288
+ W ++Y+I I YGG VTDD+D+RLL T+ +F + F S + Y
Sbjct: 4029 E---ETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYF 4085
Query: 4289 IPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVLDTILGIQPKDT-SGG 4347
IPK ++ +Y +YI LP D PE FG HPNAD+ Q A+ + DT+L +QP+ T +
Sbjct: 4086 IPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRA 4145
Query: 4348 GDETREAVVARLADDMLEKLPPDYVPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLV 4407
G +TRE V LA D+ +K+ P+ + +E ++L + P P+N+ L QEI R ++ +
Sbjct: 4146 GGQTREEKVLELAADVKQKI-PEMIDYEGTQKLLALDP-SPLNVVLLQEIQRYNTLMQTI 4203
Query: 4408 RSTLTELKLAIDGTIIMSENLRDALDCMFDARIPAWWKKASWISSTLGFWFTELIERNSQ 4467
+LT+L+ I G I+MS +L + +C+FDA +P W KA L W +L R Q
Sbjct: 4204 LFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMRVEQ 4263
Query: 4468 FTSWVFNGRPH-CFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKWMKDDIS 4526
F W RP FW++GF P GFLTA+ Q R N ++D++ V+ ++
Sbjct: 4264 FELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQN-NVSVDSLSWEFIVSTVDDSNLV 4322
Query: 4527 APPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIY-AENNTLRDPRFYSCP 4585
PP +GV+V GLYLEGAGWD++N L+E++P L LMP I AE+ YSCP
Sbjct: 4323 YPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCP 4382
Query: 4586 IYKKPVRTD----LNYIAAVDLRT-AQTPEHWVLRGVALL 4620
Y P R +++ +DLR+ A TP+HW+ RG ALL
Sbjct: 4383 CYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALL 4422
Score = 97.8 bits (242), Expect = 2e-19
Identities = 78/284 (27%), Positives = 138/284 (48%), Gaps = 22/284 (7%)
Query: 118 GNDVALTGVCVFFIRTDPSKAITPDNIHQEVSFNMLDAADGGLLNSVRRLLSDIFIPALR 177
G V V+FIR P IT +N V F + G + ++ RLL +F P +
Sbjct: 129 GMPVQTQNQLVYFIRQAPVP-ITWENFEATVQFGTVR---GPYIPALLRLLGGVFAPQIF 184
Query: 178 ATSHGWGELEGLQDAANIRQEFLSSLEGFVNVLSGAQESLKEKVNLR-KCDILELKTLKE 236
A + GW E +IR F S L F+ L+ + L+ L + + +K
Sbjct: 185 ANT-GWPE--------SIRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEM- 234
Query: 237 PTDYLTLANNPETLGKIEDCMKVWIKQTEQVLAENNQLLKEADDVGPRAELEHWKKRLSK 296
+ + E + ++E M W +Q +++L+ + ++ +++GP E+E W+ R
Sbjct: 235 ------VIKDKELVQRLETSMIHWTRQIKEMLSAQ-ETVETGENLGPLEEIEFWRNRCMD 287
Query: 297 FNYLLEQLKSPDVKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLEKCCD 356
+ + +QL VK V ++L AKS L + ++ +I D + +A+ N+ +L L++
Sbjct: 288 LSGISKQLVKKGVKHVESILHLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQ 347
Query: 357 PLYSSDPLSMMDAIPTLINAIKMIYSISHYYNTSEKITSLFVKV 400
L P + +P LI+ I++I+ S +YNT E++TSLF KV
Sbjct: 348 ELAFMKPKDISSKLPKLISLIRIIWVNSPHYNTRERLTSLFRKV 391
Score = 62.4 bits (150), Expect = 1e-08
Identities = 56/291 (19%), Positives = 117/291 (40%), Gaps = 7/291 (2%)
Query: 517 TIKKKEYNFLDQRKMDFDQDYEEFCKQTNDLHNELRKFMDVTFAKIQNTNQALRMLKKFE 576
T++ LD + + +DY +F DL + + F +++ + +L F
Sbjct: 437 TLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAFELVRDVPHGVLLLDTFH 496
Query: 577 RL---NIPNLGIDDKYQLILENYGADIDMISKLYTKQKYDPPLARNQPPIAGKILWARQL 633
RL D K + + +++ ++++ + K P L +GK W L
Sbjct: 497 RLASREAIKRTYDKKAVDLYMLFNSELALVNR--ERNKKWPDLEPYVAQYSGKARWVHIL 554
Query: 634 FHRIQQPMQLFQQHPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWLRQIEEIHVG-L 692
RI + M + K + +Y +M + + E + W +++ + L
Sbjct: 555 RRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQEWTSSLDKDCIRRL 614
Query: 693 EASLL-VKAPGTGELFVNFDPQILILFRETECMAQMGLEVSPLATSLFQKRDRYKRNFSN 751
+ LL + G L VNFD +LILF E + ++ E ++ ++ + + N
Sbjct: 615 DTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVNVAERAEDLRILREN 674
Query: 752 MKMMLAEYQRVKSKIPAAIEQLIVPHLAKVDEALQPGLAALTWTSLNIEAY 802
+ ++ +Y R+ + + + L + +D+ + PGL L W A+
Sbjct: 675 LLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAF 725
>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
Length = 4265
Score = 2020 bits (5234), Expect = 0.0
Identities = 1214/3597 (33%), Positives = 1919/3597 (53%), Gaps = 165/3597 (4%)
Query: 1124 STIINSTKKEVITSMDCFKRYNHIWQKGKEEA---IKTFITQSPLLSEFESQILYFQNLE 1180
+TI ++ K +I K Y + + +KT+ TQ L E +L +
Sbjct: 731 ATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLAQEVREVVLTHLREK 790
Query: 1181 QEINAE-PEYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIFMLIEEF 1239
+ +++ P + +G + T ++K +L+ + KA + K E+++I
Sbjct: 791 EILDSSLPSSIIIGPFYINTDNVKQSLSKKRKALATSVLDILAKNLHKEVDSICEEFRSI 850
Query: 1240 NKKLNRPIKDLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKV 1299
++K+ ++++ +K I E + ++ ++ + + Y +++ + ++ ++ +
Sbjct: 851 SRKIYEKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDK 910
Query: 1300 DTLHYAWEKLLARAGEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMASGL 1359
K+L + VQ + V + F+K I F + L
Sbjct: 911 WIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEIS 970
Query: 1360 KPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIYTLY 1419
+ E ++ + + Q + + + Y E +F LP T Y +L + K+ ++T
Sbjct: 971 RAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTA 1030
Query: 1420 NSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAF----LDLKKIIDD 1475
+ + S+ + S ++ E++ ++E K + KD A LD++ I++
Sbjct: 1031 SDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEE 1090
Query: 1476 FSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDIC 1535
F PL++ + + M RHWE ++ ++ + +E L + E I +
Sbjct: 1091 FKPYIPLIQGLRNPGMRIRHWETLSNQININVRP-KANLTFARCLEMNLQDHIESISKVA 1149
Query: 1536 ISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRG-DSTSEIIANMEDSLMLLGS 1594
A KE IEQ L ++ EW F +K +L+ D S+++ +D +++ +
Sbjct: 1150 EVAGKEYAIEQALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLL---DDHIVMTQN 1206
Query: 1595 LLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGGDIAKQLPKEAKR 1654
+ + Y PF+ +I W L + +++E W+ Q W+YLE +F DI +QLP E+KR
Sbjct: 1207 MSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQLPVESKR 1266
Query: 1655 FSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCF 1714
+ +++ W KIM A+E V+ C D + L L++ QK L+ YLE KR F
Sbjct: 1267 YQTMERIWKKIMKNAYENREVINVC-SDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAF 1325
Query: 1715 PRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDRILSISSQEGETIE 1774
PRF+F+SD LLEIL Q D +Q HL F+NI + F E + I + S EGE ++
Sbjct: 1326 PRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQEDL--EITHMYSAEGEEVQ 1383
Query: 1775 LDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLSSFPAQVGLLGI 1834
L + NVE WL + ++S+H +I +A T+++ ++P QV + G
Sbjct: 1384 LCFSIYPSSNVEDWLREVERSMKASVHDIIEKAIRAYPT--MPRTQWVLNWPGQVTIAGC 1441
Query: 1835 QMIWTRDSEEALRNAKFDKKIMQKTNQAFLELLNTLIDVTTRDLSSTERVKYETLITIHV 1894
Q WT + EAL ++ + Q L+ L+ + LS +R LI I V
Sbjct: 1442 QTYWTMEVAEALEAGNLRSQLFPQLCQQ----LSDLVALVRGKLSRMQRAVLSALIVIEV 1497
Query: 1895 HQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQNEFLGCTDRLV 1954
H +D+ L ++ S DF+W+ Q R+Y+ + + I + FIY E+LG + RLV
Sbjct: 1498 HAKDVVSKLIQENVVSVNDFQWISQLRYYWTNND--LYIRAVNAEFIYGYEYLGNSGRLV 1555
Query: 1955 ITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRG 2014
ITPLTDRCY+TL AL + GGAPAGPAGTGKTETTKD+G+ L VVFNCSDQ+DF
Sbjct: 1556 ITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMA 1615
Query: 2015 LGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMN 2074
+G+ FKGLA +G+W CFDEFNRID+ VLSV AQQI+ I +++ + F+F +G + +
Sbjct: 1616 MGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQRVERFMF-EGVEIPLV 1674
Query: 2075 PEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKF 2134
P +F+TMNPGYAGR ELP+NLK FR VAMMVPD +I + L S GF + VLA+K
Sbjct: 1675 PSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKI 1734
Query: 2135 FTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNLSKLI 2194
T +KL EQLS Q HYDFG+R + +V+ G KR NP E I +R +RD+N+ K +
Sbjct: 1735 TTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFL 1794
Query: 2195 DEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFETQRV 2254
ED LF ++ DLFP I + Y L+ AI + L + + K IQL+ET V
Sbjct: 1795 QEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVV 1854
Query: 2255 RHGMMTLGPSGAGKTTCIHTLMRAMTDC-GKPHREMRM---------NPKAITAPQMFGR 2304
RHG+M +GP+G+GK+TC L AMT G+P M NPK+IT Q++G
Sbjct: 1855 RHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGE 1914
Query: 2305 LDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANG 2364
D+ T++WTDGIFS+ R W + DGPVDAIWIEN+N+VLDDNK L L++G
Sbjct: 1915 FDLLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSG 1974
Query: 2365 DRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFLKKRSPQEAEIL 2424
+ I + ++FE ++ ASPATVSR GMV++ SIL P +E +L+K P L
Sbjct: 1975 EIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIECWLRKLPP-----L 2029
Query: 2425 RQLYTESFPDLY-RFCIQNLEYKMEVLEAFVITQSINMLQGLIPL----------KEQGG 2473
+ Y E F L+ F +++ + ++ + + + N+ L+ L +E
Sbjct: 2030 LKPYEEHFKALFVSFLEESISFVRSSVKEVIASTNCNLTMSLLKLLDCFFKPFLPREGLK 2089
Query: 2474 EVSQAHLGRL-------FVFALLWSAGAALELDGRRRLELWLRSRPTG---TLELPPPAG 2523
++ L R+ F+F+L+WS GA + GR WLR + TL P
Sbjct: 2090 KIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSGRTSFSHWLRLKMENEQLTLLFPEEG- 2148
Query: 2524 PGDTAFDYYVAPDG-----------------TWTHWNTRTQEYLYPSDTTPEYGSILVPN 2566
FDY + G W W + + DT Y +I+VP
Sbjct: 2149 ---LVFDYRLEDAGISGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVPDTN--YCNIIVPT 2203
Query: 2567 VDNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPL 2626
+D V+ L+ + K VL IG GT KT+ I + K ++ L FS+ T+
Sbjct: 2204 MDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDKLLKNLALDYISHFLTFSARTSAN 2263
Query: 2627 MFQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFY 2686
Q I+S +DKR +GPP G+ FIDD+NMP + +G Q E++RQ M+ G+Y
Sbjct: 2264 QTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWY 2323
Query: 2687 NLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIF----- 2741
+ + G F ++VDI F+ AM PGGGRN + RL R F+ + E S +IF
Sbjct: 2324 DRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILG 2383
Query: 2742 ----GVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDL 2797
G++G Y + + + LV T ++ ++LPTPAK HY FNLRDL
Sbjct: 2384 NWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDL 2443
Query: 2798 SRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGE 2857
S+V+QGML +++ LL+LW HE RV DR D +WFD+ L +E+
Sbjct: 2444 SKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCMEQWEVT 2503
Query: 2858 EKKLLVDCGIDTYFVDFLRDAPEAAGETSEEADAETPKIYEPIESFSHLKERLNMFLQLY 2917
K+ I + DF+ + K YE I S S + + + +++ Y
Sbjct: 2504 FNKVCPFQPI--LYGDFMSPGSDV-------------KSYELITSESKMMQVIEEYIEDY 2548
Query: 2918 NESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVS 2977
N+ I A + +V F DAM H+ +ISR +R GNALL+GVGGSG+ SLTRLAS +A Y
Sbjct: 2549 NQ-INTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYEC 2607
Query: 2978 FQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVS 3037
FQI L+++Y S +D+K + AG Q ITF+F+D +IK+ESFLE +NNVL+SG++
Sbjct: 2608 FQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIP 2667
Query: 3038 NLFARDEIDEINSDLASVMKKEFPRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRN 3097
NL+ DE D+I S + ++++ + PT NL + RVR N+H+VLC SP+GE FR
Sbjct: 2668 NLYTADEQDQIVSTMRPYIQEQGLQ--PTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRA 2725
Query: 3098 RALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSY-DIDCSLEIKKEVVQCMGSFQDGV 3156
R +FP+L++ CTIDWF+ WP +AL +V+ FL +++ S E + ++Q V
Sbjct: 2726 RLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQVCVYIHQSV 2785
Query: 3157 AEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASES 3216
++KC++Y R +VTPKSYL + + + G+K +E++T NRM +GL+KL SE
Sbjct: 2786 SKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSED 2845
Query: 3217 VAALSKELE---------AKEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQ 3267
VA + ++LE AK+ L + K D + E T + E++KA +K K +AQ
Sbjct: 2846 VAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKAN-EKAK-KAQ 2903
Query: 3268 AIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVL 3327
AI D KD L+ A PAL+ A A+L+ + +D+ VR + RPP + +++ V
Sbjct: 2904 AIADDAQKD-------LDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVC 2956
Query: 3328 LLFQRKVSAVKIDLEKSCTMPS--WQESLKLMT-AGNFLQNLQQFPKDTINEEVIEFLSP 3384
++ + + K+ EK T W+ L+ G+FL++L +F KD I + VI+ + P
Sbjct: 2957 IM--KGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQP 3014
Query: 3385 YFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQENRHLLAMQDL 3444
Y + ++ T +V +C W +AM + + K V P + L+ ++ + + L
Sbjct: 3015 YIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRIL 3074
Query: 3445 QKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLAGEKERWT 3504
+A+ L + + + +QA+Y + +T+K+ L E+C ++ A LI+GL+ EK RW
Sbjct: 3075 DEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQ 3134
Query: 3505 EQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLNDWRKEMKARKIPFGKNLNLS 3564
E + + GDVL+A F++Y GPF ++R +L + W K++++ +P L
Sbjct: 3135 ETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQLRSHNVPHTSEPTLI 3194
Query: 3565 EMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESRNELQ 3624
L + I W + GLPND LS++NG+I + R+ IDPQ+Q WIKN E N L
Sbjct: 3195 GTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGLD 3254
Query: 3625 ITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTGSTFKVKVGDKEV 3684
+ L+ + F +E+++ G+P L+E+VGEELDPAL+ VL + K +K+GD +
Sbjct: 3255 VFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVI 3314
Query: 3685 DVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEKERT 3744
+ FR+YITTKLPNP YTPEIS + ++I+FT++ GLEDQLLG+V+ E+ +LE+ +
Sbjct: 3315 PYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKN 3374
Query: 3745 HLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEVTQKLEISAE 3804
L+ ++ +K++ED +LYRL+S++G+ V+D LI VL +K A E+ K+ I+ +
Sbjct: 3375 QLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQ 3434
Query: 3805 TEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSLARSVKSPIT 3864
TE I+ R EY PVA R IL+F ++++ V+ MYQ SL FL +F +A S ++
Sbjct: 3435 TEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNL 3494
Query: 3865 SKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEFLTLIKGGAS 3924
KRI+NI ++TY +Y R L+E+HK +F LL ++I + ++ E+ L+ GG S
Sbjct: 3495 KKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLLSGG-S 3553
Query: 3925 LDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIWFDKENPEEEPLP 3984
+ + P P W+ D W +++ LS L FS ++ +++ FD P EPLP
Sbjct: 3554 ISIMTENPAPD-WLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHREPLP 3612
Query: 3985 NAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLEKTWEESDPRTP 4044
+D+ LD F++LL++R D+ + ++ ++ ++ E +L +++S+ TP
Sbjct: 3613 GIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTP 3672
Query: 4045 LICLLSMGSDPTDSIIALGKRLKIETRY--VSMGQGQEVHARKLLQQTMANGGWALLQNC 4102
LI +LS G+DP + + +K + +S+GQGQ A +++ ++ G W QNC
Sbjct: 3673 LIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNC 3732
Query: 4103 HLGLDFMDELMDII--IETELVHDAFRLWMTTEAHKQFPITLLQMSIKFANDPPQGLRAG 4160
HL +M L +I I + VH FRLW+T+ +FP+++LQ K +PP+G+RA
Sbjct: 3733 HLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVRAN 3792
Query: 4161 LKRTYSGVSQDLLD-VSSGSQWKPMLYAVAFLHSTVQERRKFGALGWNIPYEFNQADFNA 4219
L ++YS + +D L+ ++K +L ++ H ERRKFG LG+NIPYEF D
Sbjct: 3793 LLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRI 3852
Query: 4220 TVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFGP 4279
+ ++ LD+ D + + ++Y GEI YGGRVTDD+D+R + + +++ ++ P
Sbjct: 3853 CISQLKMFLDEYD---DIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSP 3909
Query: 4280 DFSFYQG---YNIPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVLDTI 4336
+ S+ + IP + YL YI+SLP D PE+FGLH NA+IT+ +L TI
Sbjct: 3910 EHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTI 3969
Query: 4337 LGIQPKDTSGGGDETREAVVARLADDMLEKLPPDYVPFEVKERLQKMGPF--QPMNIFLR 4394
+ +QPK +S G + RE +V + ++L K+P P ++ + K + MN L
Sbjct: 3970 IQLQPK-SSSAGSQGREEIVEDVTQNILLKVPE---PINLQWVMAKYPVLYEESMNTVLV 4025
Query: 4395 QEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDARIPAWWKKASWIS-ST 4453
QE+ R R+L ++ TL +L A+ G ++MS L +++ +P W ++ S
Sbjct: 4026 QEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKP 4085
Query: 4454 LGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVL 4513
L W +L++R +W+ +G P FW++GFF PQ FLT Q R ++D +
Sbjct: 4086 LSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFAR-KFVISIDTISF 4144
Query: 4514 CNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIY-AE 4572
+V +++ P G Y++GL+LEGA WD +L ES+PK L+ M VI +
Sbjct: 4145 DFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTP 4204
Query: 4573 NNTLRDPRFYSCPIYKKPVRT--------DLNYIAAVDLRTAQTPEHWVLRGVALLC 4621
N +D FY CPIYK R NY+ AV++ T Q HW+ RGVAL+C
Sbjct: 4205 NRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALIC 4261
>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4470
Score = 1950 bits (5051), Expect = 0.0
Identities = 1193/3613 (33%), Positives = 1935/3613 (53%), Gaps = 152/3613 (4%)
Query: 1083 ENELQDTLEIASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTIINSTKKEVITSMDCFK 1142
E + D +A + + NY ++ +N +++++ +S+++ + KE D F+
Sbjct: 938 EGLVNDIYNVARLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFE 997
Query: 1143 RYNHIWQKGKEEAIKTFITQS--------------------PLLSEFESQILYFQNLEQE 1182
RY+++W +E +K F+ P L++F+ QI ++ L +E
Sbjct: 998 RYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEE 1057
Query: 1183 IN-AEPEYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIFMLIEEFNK 1241
++ E V G + K AL + + W + RH + + + ++ ++
Sbjct: 1058 VSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARM 1117
Query: 1242 KLNRPIK--DLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKV 1299
L +P+K D D + M L +++E Q + D P++++ LL YG + E K+
Sbjct: 1118 GLTKPLKEGDYDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKL 1177
Query: 1300 DTLHYAWEKLLARAGEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMA-SG 1358
L W A +V+ + LQ + L + F H+F + P + S
Sbjct: 1178 QELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSD 1237
Query: 1359 LKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIYTL 1418
P ++ ++ + + I ++ +GG LF +P Y QL +++ LL++++ +
Sbjct: 1238 PNPYKSLNKQQKSISAMEGIMEA-LSKSGG--LFEVPVPDYKQLKACHREVRLLKELWDM 1294
Query: 1419 YNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKKIIDDFSE 1478
V ++ + W ++N+E+++ + +F R L + +K W AF+ L + +
Sbjct: 1295 VVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVIT 1354
Query: 1479 CCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDICISA 1538
+ + + A+ ERHW+++ T + E+ L ++++ L Y++E+ +I A
Sbjct: 1355 SLRAVSELQNPAIRERHWQQLMQATQVKFKMSEET-TLADLLQLNLHSYEDEVRNIVDKA 1413
Query: 1539 VKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEIIANMEDSLMLLGSLLSN 1598
VKE +E+ LK + + W F G ++L+ S+ ++ +ED+ + L +L+ +
Sbjct: 1414 VKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLK--SSEVLVETLEDNQVQLQNLMMS 1471
Query: 1599 RYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGG-DIAKQLPKEAKRFSN 1657
+Y F ++ W Q LS + +I W VQ W +LE++F+G DI QLP +++RF +
Sbjct: 1472 KYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDD 1531
Query: 1658 IDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRF 1717
I++ + +M A + P+VV+ L L L L IC+K+L YLE KRL FPRF
Sbjct: 1532 INQEFKALMEDAVKTPNVVEA-TSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRF 1590
Query: 1718 FFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDRILSIS----SQEGETI 1773
+FVS LL+IL +D + HL +FD++ +KF D+ L + S+E E +
Sbjct: 1591 YFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYM 1650
Query: 1774 ELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLSSFPAQVGLLG 1833
D+ G VEVWLN +L+ S+L I +A +E + +++ +PAQV L
Sbjct: 1651 VFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPRE--QWILDYPAQVALTC 1708
Query: 1834 IQMIWTRDSEEALRNAKFDK---KIMQKTNQAFLELLNTLIDVTTRDLSSTERVKYETLI 1890
Q+ WT +E L A+ ++ ++ N+ + LN LI + +L++ +R+K T+
Sbjct: 1709 TQIWWT--TEVGLAFARLEEGYENAIRDYNKKQISQLNVLITLLMGNLNAGDRMKIMTIC 1766
Query: 1891 TIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQNEFLGCT 1950
TI VH RD+ + ++S F W Q R ++E+ +I D Y E+LG T
Sbjct: 1767 TIDVHARDVVAKMIVAKVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNT 1826
Query: 1951 DRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQM 2010
RLVITPLTDRCYITL Q+L + MGGAPAGPAGTGKTETTKD+GR LG V VFNCS+QM
Sbjct: 1827 PRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQM 1886
Query: 2011 DFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDN 2070
D++ G I+KGLAQ+G+WGCFDEFNRI + VLSV A Q+ + + KK+F F G+
Sbjct: 1887 DYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFL-GEI 1945
Query: 2071 VTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVL 2130
+ + P G+F+TMNPGYAGR ELPENLK FR AM+VPD ++I + L + GF++ +L
Sbjct: 1946 IGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLL 2005
Query: 2131 ARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNL 2190
ARKF TLY LC+E LSKQ HYD+GLR I SVL G+ KR +P E ++MR LRD N+
Sbjct: 2006 ARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNI 2065
Query: 2191 SKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFE 2250
K++ +D P+F+ LI DLFP + + + E I + + E L + LKV+QL E
Sbjct: 2066 PKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEE 2125
Query: 2251 TQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKPHREMRMNPKAITAPQMFGRLDVATN 2310
+VRH + +G +G+GK+ + +L + + + + ++PKA+T ++FG ++ T
Sbjct: 2126 LLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPVTR 2185
Query: 2311 DWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMA 2370
+W DG+FST+ R WIILDG +D +WIE+LN+V+DDNK LTLA+ +RIP+
Sbjct: 2186 EWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLN 2245
Query: 2371 PNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFLKKRSPQEAE----ILRQ 2426
+++FE ++ A+PATVSR G+++++ + L W+P++ ++++R Q + IL
Sbjct: 2246 RTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFD 2305
Query: 2427 LYTESFPDLYRFCIQNLEYKMEVLEAFVITQSINMLQGLIPLKEQGGEVSQAHLGRLFVF 2486
Y + D RF + + V E VI + +L+ L+ K + + FVF
Sbjct: 2306 KYLPTCLDKLRFGFKKI---TPVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVF 2362
Query: 2487 ALLWSAGAAL----ELDGRRRLELWLRSRPTGTLELPPPAGPGDTAFDYYVAPDGTWTHW 2542
W+ G A+ +D R W + T++ P T FDYY+ PD
Sbjct: 2363 TCFWAFGGAMFQDQLVDYRVEFSKWWINE-FKTIKFPSQG----TIFDYYIDPD------ 2411
Query: 2543 NTRTQEYLYPSDTTPEY--------GSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQGT 2594
T+++L +D P + + LV + +R + + + ++ V+L+G GT
Sbjct: 2412 ---TKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGT 2468
Query: 2595 AKTVIIKGFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKMTV 2654
K+V++ + + + ++++++ F+ TT M Q +E ++K+ G YGPP KK+
Sbjct: 2469 GKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVY 2528
Query: 2655 FIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRN 2714
FIDD+NMP ++++G + ++RQ M+ +Y+ K I + Q++A M +P G
Sbjct: 2529 FIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKL-TLKDIHNCQYVACM-NPTSGSF 2586
Query: 2715 DIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLW 2774
I RL+R F +F + P + ++ I+ I H R S ++ ++LV L
Sbjct: 2587 TIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAF-RSVSMAIQRISSQLVAAALALH 2645
Query: 2775 QMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIADRF 2834
Q LPT KFHYVFNLRDLS ++QG+L +T+EV+K P DL++LW HE +RV D+
Sbjct: 2646 QKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKM 2705
Query: 2835 TVSSDVTWFDKALVSLVEEEFGE--EKKLLVDCGIDTYFVDFLRDAPEAAGETSEEADAE 2892
D + ++ ++ F + ++ L I +F + D
Sbjct: 2706 VDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGD--------------- 2750
Query: 2893 TPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNA 2952
PK Y P+ + L + L L YNE A M++V F DA+ H+ +I+R++ +P+GNA
Sbjct: 2751 -PK-YVPVTDMAPLNKLLVDVLDSYNEV--NAVMNLVLFEDAVAHICRINRILESPRGNA 2806
Query: 2953 LLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFI 3012
LLVGVGGSGKQSL+RLA++I+G FQITL + Y +L DL Y A + F+
Sbjct: 2807 LLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFL 2866
Query: 3013 FTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNENLHD 3072
TD+++ +E FL +N++L+SGE+ LF DE++ I S + +K T E
Sbjct: 2867 MTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMN--DTRETCWK 2924
Query: 3073 YFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTS 3132
+F+ +VR+ L ++LCFSPVG R RA KFPA+++ IDWF WP+DALV+VS FL
Sbjct: 2925 FFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLE- 2983
Query: 3133 YDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEK 3192
+ + IK + M V E Y RR + TPK++L I+ Y+ + +K
Sbjct: 2984 -ETEGIPVIKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKK 3042
Query: 3193 HVEVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAA 3252
E+ R+ GL KL+ + V L +L +E EL+ N+ AD +++ V ++A+
Sbjct: 3043 RTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKV 3102
Query: 3253 EKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTL 3312
K KA + + + + I ++++ + E L A+PAL A+ AL T+ +++ +++
Sbjct: 3103 SKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSF 3162
Query: 3313 GRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLM-TAGNFLQNLQQFPK 3371
G PP ++ + V++L KI +K SW+ + +M FL +L++F K
Sbjct: 3163 GSPPDAVVNVTAAVMIL---TAPGGKIPKDK-----SWKAAKIMMGKVDTFLDSLKKFDK 3214
Query: 3372 DTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLV 3431
+ I E ++ PY P ++ E + AGLCSW + F+ + +V P + L
Sbjct: 3215 EHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALE 3274
Query: 3432 VQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTAST 3491
A + L + + ++ + A L + + +E+A EK ++A+ + A+
Sbjct: 3275 EANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANR 3334
Query: 3492 LISGLAGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLND-WRKEM 3550
L+ GLA E RW E + F +Q L GDVLL +AF+SY G F +++R+ L+ W +
Sbjct: 3335 LVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYI 3394
Query: 3551 KARK--IPFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQT 3608
K IP L+ +L D ++ WN QGLP+D +S +N I+ R+PL++D Q
Sbjct: 3395 HNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQL 3454
Query: 3609 QGKIWIKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNF 3668
QG WIKNK R+EL+ L K + + +E ++S G LLIE++GE +DP LD +L RN
Sbjct: 3455 QGIKWIKNK-YRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNT 3513
Query: 3669 IKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLL 3728
IK G +K+GDKEV+ FRL + TK NP Y PE+ A+ ++I+F VT GLEDQLL
Sbjct: 3514 IKKGK--YIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLL 3571
Query: 3729 GRVILTEKQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNT 3788
V+ E+ +LE+ + +L + K +KELED+LL RL++ G+ + D +L+ L T
Sbjct: 3572 AAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETT 3631
Query: 3789 KRTAEEVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFL 3848
K TA E+ +K+ + TEV+IN ARE YRP A R S+LYF++ ++ +N +YQ SL+ F
Sbjct: 3632 KHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFN 3691
Query: 3849 GLFDLSLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRN 3908
+F+ ++ R+ + +R+ N+ + +TY VY Y ARGL+E K +F +T ++ +
Sbjct: 3692 VVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKK 3751
Query: 3909 RVKHEEFLTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKM 3968
+ E L++ KA P ++ W + LS++ +F ++ I + K
Sbjct: 3752 ELNPVELDFLLR----FPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKR 3807
Query: 3969 WKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGV 4028
WK + E PE+E P + K+ ++L ++R PDR + ++ + MG K+ EG
Sbjct: 3808 WKKLVESEAPEKEIFPKEW-KNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGR 3866
Query: 4029 ILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKI-----ETRYVSMGQGQEVHA 4083
++ K++EES P T + +LS G DP + ALGK+L + VS+GQGQEV A
Sbjct: 3867 SVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVA 3926
Query: 4084 RKLLQQTMANGGWALLQNCHLGLDFMDELMDIIIETELV--HDAFRLWMTTEAHKQ---- 4137
L G W +LQN HL ++ L D +E H+ +R++++ E
Sbjct: 3927 ENALDVAAEKGHWVILQNIHLVARWLGTL-DKKLERYSTGSHEDYRVFISAEPAPSPETH 3985
Query: 4138 -FPITLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDV-SSGSQWKPMLYAVAFLHSTV 4195
P +L+ +IK N+PP G+ A L + +QD L++ + ++K ML+A+ + H+ V
Sbjct: 3986 IIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVV 4045
Query: 4196 QERRKFGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRV 4255
ERRKFGA GWN Y FN D ++ + N+L + V W +RY+ GEI YGG +
Sbjct: 4046 AERRKFGAQGWNRSYPFNNGDLTISINVLYNYL---EANPKVPWDDLRYLFGEIMYGGHI 4102
Query: 4256 TDDYDKRLLNTFAKVWFSENMFGPDFSFYQGYNIPKCSTVDNYLQYIQSLPAYDSPEVFG 4315
TDD+D+RL T+ + M D G+ IP Y +YI +SP ++G
Sbjct: 4103 TDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYG 4162
Query: 4316 LHPNADITYQSKLAKDVLDTILGIQPKDTSGGGDE--TREAVVARLADDMLEKLPPDYVP 4373
LHPNA+I + + ++ + T+L +QPK+T G +RE V + DD+LEK+P
Sbjct: 4163 LHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKIPE---T 4219
Query: 4374 FEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALD 4433
F + E + K P + QE +RM + + +R +L EL L + G + ++ ++ D
Sbjct: 4220 FNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLST 4279
Query: 4434 CMFDARIPAWWKKASWISST-LGFWFTELIERNSQFTSWVFN-GRPHCFWMTGFFNPQGF 4491
+F +P W ++ S L W+ +L+ R + +W + P W+ GFFNPQ F
Sbjct: 4280 ALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSF 4339
Query: 4492 LTAMRQEITRANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMK 4551
LTA+ Q + R N+ W LD M L EVTK ++D++APP EG YVYGL++EGA WD +
Sbjct: 4340 LTAIMQSMARKNE-WPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGV 4398
Query: 4552 LIESKPKVLFELMPVIRIYA-ENNTLRDPRFYSCPIYKKPVRTDLNYIAAVDLRTAQTPE 4610
+ E++ K L MPVI I A + + Y CP+YK +R Y+ +L+T +
Sbjct: 4399 IAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGP-TYVWTFNLKTKEKAA 4457
Query: 4611 HWVLRGVALLCDV 4623
W+L VALL V
Sbjct: 4458 KWILAAVALLLQV 4470
Score = 155 bits (391), Expect = 1e-36
Identities = 148/641 (23%), Positives = 283/641 (44%), Gaps = 67/641 (10%)
Query: 250 LGKIEDCMKVWIKQTEQVLAENN-QLLKEADDVGPRAELEHWKKRLSKFNYLLEQLKSPD 308
L IE + W Q VL++++ Q L + P+ E E W RL + EQL P
Sbjct: 190 LHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQLNRPK 249
Query: 309 VKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLEKCCDPLYSSDPLSMMD 368
V ++ +L AKS + + +T+ EA D V YL L + + +D +
Sbjct: 250 VNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQADFTMLPT 309
Query: 369 AIPTLINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAYITNNGTASIWNQPQDVV 428
I +++ I I++ S YYNT +I + + NQII + +++ P++V+
Sbjct: 310 FIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLS----------PEEVL 359
Query: 429 E------EKILSAI--------KLKQEYQLCFHKTKQKLKQNPNAKQFDFSEMYIFGKFE 474
+ E++LS I +L Q Y C K K + ++F F +
Sbjct: 360 KGLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFK-DKEPVPWEFPSSLAFSRIN 418
Query: 475 TFHRRLAKIIDIFTTLKTYSVLQDSTIEG-----LEDMATK-YQGIVATIK---KKEYN- 524
+F +R+ I +++ T + L+ + G L + T+ Y + +K +Y+
Sbjct: 419 SFFQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDP 478
Query: 525 -----------FLDQRKMDFDQDYEEFCKQTNDLHNELRKFMDVTF---AKIQNTNQALR 570
LD+ +FD+DY +F + DL L F + I+++ + L
Sbjct: 479 LDPGDSVGPRAGLDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLY 538
Query: 571 MLKKFERLNIPNLGIDDKYQLILENYGADIDMISKLYTKQKYD------PPLARNQPPIA 624
M + + +Y ++LE + A++D LY Q P + +N PP+A
Sbjct: 539 MCGGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVA 598
Query: 625 GKILWARQLFHRIQQPMQLFQ--QHPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWL 682
G++ W+ +L R++ M+ + +HP V+S AEAK + Y+ M ++L ++ W+
Sbjct: 599 GQLKWSLELQERLEVSMKHLKHVEHP-VMSGAEAKLTYQKYDEMMELLRCHREKIYQQWV 657
Query: 683 RQI-EEIHVGLEASLLVKAPGTGELFVNFDPQILILFRETECM-AQMGLEVSPLATSLFQ 740
+ ++ H L L+++ + + VNF ++ + RE + + Q E+ A SLF
Sbjct: 658 AGVDQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFS 717
Query: 741 KRDRYKRNFSNMKMMLAEYQRVKSKIPAAIEQLIV-PHLAKVDEALQPGLAALTWTSLNI 799
+ + +++ N+++++ Y V A+E L++ L +D L L W +
Sbjct: 718 ENETFRKFVGNLELIVGWYNEVMK----AVEFLLIKSELEAIDVKLLSAETTLFWNGEGV 773
Query: 800 EAYLENTFAKIKDLELLLDRVNDLIEFRIDAILEEMSSTPL 840
Y++ + +L+ + + IE I +++ S+ PL
Sbjct: 774 FQYIQEVREILHNLQNRMQKAKQNIE-GISQAMKDWSANPL 813
>gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 1921 bits (4977), Expect = 0.0
Identities = 1188/3643 (32%), Positives = 1930/3643 (52%), Gaps = 188/3643 (5%)
Query: 1083 ENELQDTLEIASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTIINSTKKEVITSMDCFK 1142
E + D +A + + NY ++ +N +++++ +S+++ + KE D F+
Sbjct: 929 EGLVNDIYNVARLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFE 988
Query: 1143 RYNHIWQKGKEEAIKTFITQS--------------------PLLSEFESQILYFQNLEQE 1182
RY+++W +E +K F+ P L++F+ QI ++ L +E
Sbjct: 989 RYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEE 1048
Query: 1183 IN-AEPEYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIFMLIEEFNK 1241
++ E V G + K AL + + W + RH + + + ++ ++
Sbjct: 1049 VSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARM 1108
Query: 1242 KLNRPIK--DLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKV 1299
L +P+K D D + M L +++E Q + D P++++ LL YG + E K+
Sbjct: 1109 GLTKPLKEGDYDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKL 1168
Query: 1300 DTLHYAWEKLLARAGEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMA-SG 1358
L W A +V+ + LQ + L + F H+F + P + S
Sbjct: 1169 QELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSD 1228
Query: 1359 LKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIYTL 1418
P ++ +++ + + + + + +GG LF +P Y QL +++ LL++++ +
Sbjct: 1229 PNPYKSLNKVFLLKGIMEALSK-----SGG--LFEVPVPDYKQLKACHREVRLLKELWDM 1281
Query: 1419 YNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKKIIDDFSE 1478
V ++ + W ++N+E+++ + +F R L + +K W AF+ L + +
Sbjct: 1282 VVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVIT 1341
Query: 1479 CCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDICISA 1538
+ + + A+ ERHW+++ T + E+ L ++++ L Y++E+ +I A
Sbjct: 1342 SLRAVSELQNPAIRERHWQQLMQATQVKFKMSEET-TLADLLQLNLHSYEDEVRNIVDKA 1400
Query: 1539 VKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEIIANMEDSLMLLGSLLSN 1598
VKE +E+ LK + + W F G ++L+ S+ ++ +ED+ + L +L+ +
Sbjct: 1401 VKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLK--SSEVLVETLEDNQVQLQNLMMS 1458
Query: 1599 RYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGG-DIAKQLPKEAKRFSN 1657
+Y F ++ W Q LS + +I W VQ W +LE++F+G DI QLP +++RF +
Sbjct: 1459 KYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDD 1518
Query: 1658 IDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRF 1717
I++ + +M A + P+VV+ L L L L IC+K+L YLE KRL FPRF
Sbjct: 1519 INQEFKALMEDAVKTPNVVEA-TSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRF 1577
Query: 1718 FFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDRILSIS----SQEGETI 1773
+FVS LL+IL +D + HL +FD++ +KF D+ L + S+E E +
Sbjct: 1578 YFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYM 1637
Query: 1774 ELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLSSFPAQVGLLG 1833
D+ G VEVWLN +L+ S+L I +A +E + +++ +PAQ+
Sbjct: 1638 VFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPRE--QWILDYPAQIW--- 1692
Query: 1834 IQMIWTRDSEEALRNAKFDK---KIMQKTNQAFLELLNTLIDVTTRDLSSTERVKYETLI 1890
WT +E L A+ ++ ++ N+ + LN LI + +L++ +R+K T+
Sbjct: 1693 ----WT--TEVGLAFARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNAGDRMKIMTIC 1746
Query: 1891 TIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQNEFLGCT 1950
TI VH RD+ + M ++S F W Q R ++E+ +I D Y E+LG T
Sbjct: 1747 TIDVHARDV---VAKMIVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNT 1803
Query: 1951 DRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQM 2010
RLVITPLTDRCYITL Q+L + MGGAPAGPAGTGKTETTKD+GR LG V VFNCS+QM
Sbjct: 1804 PRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQM 1863
Query: 2011 DFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDN 2070
D++ G I+KGLAQ+G+WGCFDEFNRI + VLSV A Q+ + + KK+F F G+
Sbjct: 1864 DYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFL-GEI 1922
Query: 2071 VTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVL 2130
+ + P G+F+TMNPGYAGR ELPENLK FR AM+VPD ++I + L + GF++ +L
Sbjct: 1923 IGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLL 1982
Query: 2131 ARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNL 2190
ARKF TLY LC+E LSKQ HYD+GLR I SVL G+ KR +P E ++MR LRD N+
Sbjct: 1983 ARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNI 2042
Query: 2191 SKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFE 2250
K++ +D P+F+ LI DLFP + + + E I + + E L + LKV+QL E
Sbjct: 2043 PKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEE 2102
Query: 2251 TQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKPHREMRMNPKAITAPQMFGRLDVATN 2310
+VRH + +G +G+GK+ + +L + + + + ++PKA+T ++FG ++ T
Sbjct: 2103 LLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPVTR 2162
Query: 2311 DWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMA 2370
+W DG+FST+ R WIILDG +D +WIE+LN+V+DDNK LTLA+ +RIP+
Sbjct: 2163 EWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLN 2222
Query: 2371 PNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFLKKRSPQEAE----ILRQ 2426
+++FE ++ A+PATVSR G+++++ + L W+P++ ++++R Q + IL
Sbjct: 2223 RTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFD 2282
Query: 2427 LYTESFPDLYRFCIQNLEYKMEVLEAFVITQSINMLQGLIPLKEQGGEVSQAHLGRLFVF 2486
Y + D RF + + V E VI + +L+ L+ K + + FVF
Sbjct: 2283 KYLPTCLDKLRFGFKKIT---PVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVF 2339
Query: 2487 ALLWSAGAALE----LDGRRRLELWLRSRPTGTLELPPPAGPGDTAFDYYVAPDGT-WTH 2541
W+ G A+ +D R W + T++ P T FDYY+ PD +
Sbjct: 2340 TCFWAFGGAMFQDQLVDYRVEFSKWWINE-FKTIKFPSQG----TIFDYYIDPDTKKFLP 2394
Query: 2542 WNTRTQEYLYPSDTTPEYGSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIK 2601
W + + D + + LV + +R + + + ++ V+L+G GT K+V++
Sbjct: 2395 WTDKVPSFELDPDVPLQ--ASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMG 2452
Query: 2602 GFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNM 2661
+ + + ++++++ F+ TT M Q +E ++K+ G YGPP KK+ FIDD+NM
Sbjct: 2453 DKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNM 2512
Query: 2662 PIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLK 2721
P ++++G + ++RQ M+ +Y+ K I + Q++A M +P G I RL+
Sbjct: 2513 PEVDKYGTVAPHTLIRQHMDHRHWYDRHKL-TLKDIHNCQYVACM-NPTSGSFTIDSRLQ 2570
Query: 2722 RQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKM 2781
R F +F + P + ++ I+ I H R S ++ ++LV L Q
Sbjct: 2571 RHFCVFAVSFPGQEALTTIYNTILTQHLAF-RSVSMAIQRISSQLVAAALALHQKITATF 2629
Query: 2782 LPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIADRFTVSSDVT 2841
LPT KFHYVFNLRDLS ++QG+L +T+EV+K P DL++LW HE +RV D+ D
Sbjct: 2630 LPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQE 2689
Query: 2842 WFDKALVSLVEEEFGE--EKKLLVDCGIDTYFVDFLRDAPEAAGETSEEADAETPKIYEP 2899
+ ++ ++ F + ++ L I +F + D PK Y P
Sbjct: 2690 TLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGD----------------PK-YVP 2732
Query: 2900 IESFSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVGVGG 2959
+ + L + L L YNE A M++V F DA+ H+ +I+R++ +P+GNALLVGVGG
Sbjct: 2733 VTDMAPLNKLLVDVLDSYNEV--NAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGG 2790
Query: 2960 SGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIK 3019
SGKQSL+RLA++I+G FQITL + Y +L DL Y A + F+ TD+++
Sbjct: 2791 SGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVA 2850
Query: 3020 DESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNENLHDYFMSRVR 3079
+E FL +N++L+SGE+ LF DE++ I S + +K T E +F+ +VR
Sbjct: 2851 EEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMN--DTRETCWKFFIEKVR 2908
Query: 3080 QNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSYDIDCSL 3139
+ L ++LCFSPVG R RA KFPA+++ IDWF WP+DALV+VS FL +
Sbjct: 2909 RQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETE-GIPW 2967
Query: 3140 EIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTL 3199
E+K + M V E Y RR + TPK++L I+ Y+ + +K E+
Sbjct: 2968 EVKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAK 3027
Query: 3200 ANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEV 3259
R+ GL KL+ + V L +L +E EL+ N+ AD +++ V ++A+ K KA
Sbjct: 3028 IERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIA 3087
Query: 3260 QKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLI 3319
+ + + + I ++++ + E L A+PAL A+ AL T+ +++ +++ G PP +
Sbjct: 3088 DQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAV 3147
Query: 3320 MRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLM-TAGNFLQNLQQFPKDTINEEV 3378
+ + V++L KI +KS W+ + +M FL +L++F K+ I E
Sbjct: 3148 VNVTAAVMIL---TAPGGKIPKDKS-----WKAAKIMMGKVDTFLDSLKKFDKEHIPEAC 3199
Query: 3379 IEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQENRHL 3438
++ PY P ++ E + AGLCSW + F+ + +V P + L
Sbjct: 3200 LKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELA 3259
Query: 3439 LAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLAG 3498
A + L + + ++ + A L + + +E+A EK ++A+ + A+ L+ GLA
Sbjct: 3260 EAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLAS 3319
Query: 3499 EKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLND-WRKEMKARK--I 3555
E RW E + F +Q L GDVLL +AF+SY G F +++R+ L+ W + K I
Sbjct: 3320 ENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPI 3379
Query: 3556 PFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIK 3615
P L+ +L D ++ WN QGLP+D +S +N I+ R+PL++D Q QG WIK
Sbjct: 3380 PITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIK 3439
Query: 3616 NKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTGSTF 3675
NK R+EL+ L K + + +E ++S G LLIE++GE +DP LD +L RN IK G
Sbjct: 3440 NKY-RSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKY- 3497
Query: 3676 KVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTE 3735
+K+GDKEV+ FRL + TK NP Y PE+ A+ ++I+F VT GLEDQLL V+ E
Sbjct: 3498 -IKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKE 3556
Query: 3736 KQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEV 3795
+ +LE+ + +L + K +KELED+LL RL++ G+ + D +L+ L TK TA E+
Sbjct: 3557 RPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEI 3616
Query: 3796 TQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSL 3855
+K+ + TEV+IN ARE YRP A R S+LYF++ ++ +N +YQ SL+ F +F+ ++
Sbjct: 3617 EEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAI 3676
Query: 3856 ARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEF 3915
R+ + +R+ N+ + +TY VY Y ARGL+E K +F +T ++ + + E
Sbjct: 3677 QRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVEL 3736
Query: 3916 LTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIWFDK 3975
L++ KA P ++ W + LS++ +F ++ I + K WK +
Sbjct: 3737 DFLLR----FPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVES 3792
Query: 3976 ENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLEKT 4035
E PE+E P + K+ ++L ++R PDR + ++ + MG K+ EG ++ K+
Sbjct: 3793 EAPEKEIFPKEW-KNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKS 3851
Query: 4036 WEESDPRTPLICLLSMGSDPTDSIIALGKRLKI-----ETRYVSMGQGQEVHARKLLQQT 4090
+EES P T + +LS G DP + ALGK+L + VS+GQGQEV A L
Sbjct: 3852 YEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVA 3911
Query: 4091 MANGGWALLQ--------NCHLGLDFMDELMDIIIETELV--HDAFRLWMTTEAHKQ--- 4137
G W +LQ N HL ++ L D +E H+ +R++++ E
Sbjct: 3912 AEKGHWVILQVRGGQHCRNIHLVARWLGTL-DKKLERYSTGSHEDYRVFISAEPAPSPET 3970
Query: 4138 --FPITLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSGS-QWKPMLYAVAFLHST 4194
P +L+ +IK N+PP G+ A L + +QD L++ + ++K ML+A+ + H+
Sbjct: 3971 HIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAV 4030
Query: 4195 VQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGR 4254
V ERRKFGA GWN Y FN D ++ + N+L+ V W +RY+ GEI YGG
Sbjct: 4031 VAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLE---ANPKVPWDDLRYLFGEIMYGGH 4087
Query: 4255 VTDDYDKRLLNTFAKVWFSENMFGPDFSFYQGYNIPKCSTVDNYLQYIQSLPAYDSPEVF 4314
+TDD+D+RL T+ + M D G+ IP Y +YI +SP ++
Sbjct: 4088 ITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLY 4147
Query: 4315 GLHPNADITYQSKLAKDVLDTILGIQPKDTSGGGDE--TREAVVARLA------------ 4360
GLHPNA+I + + ++ + T+L +QPK+T G +RE L
Sbjct: 4148 GLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLE 4207
Query: 4361 -----------------DDMLEKLPPDYVPFEVKERLQKMGPFQPMNIFLRQEIDRMQRV 4403
DD+LEK+P F + E + K P + QE +RM +
Sbjct: 4208 LRRGGCPGTGFQVKAVLDDILEKIPET---FNMAEIMAKAAEKTPYVVVAFQECERMNIL 4264
Query: 4404 LSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDARIPAWWKKASWISST-LGFWFTELI 4462
+ +R +L EL L + G + ++ ++ D +F +P W ++ S L W+ +L+
Sbjct: 4265 TNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLL 4324
Query: 4463 ERNSQFTSWVFN-GRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKWM 4521
R + +W + P W+ GFFNPQ FLTA+ Q + R N+ W LD M L EVTK
Sbjct: 4325 LRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNE-WPLDKMCLSVEVTKKN 4383
Query: 4522 KDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIYA-ENNTLRDPR 4580
++D++APP EG YVYGL++EGA WD + + E++ K L MPVI I A + +
Sbjct: 4384 REDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKN 4443
Query: 4581 FYSCPIYKKPVRTDLNYIAAVDLRTAQTPEHWVLRGVALLCDV 4623
Y CP+YK +R Y+ +L+T + W+L VALL V
Sbjct: 4444 IYECPVYKTRIRGP-TYVWTFNLKTKEKAAKWILAAVALLLQV 4485
Score = 168 bits (426), Expect = 1e-40
Identities = 148/628 (23%), Positives = 282/628 (44%), Gaps = 50/628 (7%)
Query: 250 LGKIEDCMKVWIKQTEQVLAENN-QLLKEADDVGPRAELEHWKKRLSKFNYLLEQLKSPD 308
L IE + W Q VL++++ Q L + P+ E E W RL + EQL P
Sbjct: 190 LHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQLNRPK 249
Query: 309 VKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLEKCCDPLYSSDPLSMMD 368
V ++ +L AKS + + +T+ EA D V YL L + + +D +
Sbjct: 250 VNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQADFTMLPT 309
Query: 369 AIPTLINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAYITNNGTASIWNQPQDVV 428
I +++ I I++ S YYNT +I + + NQII + +++ P++V+
Sbjct: 310 FIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLS----------PEEVL 359
Query: 429 E------EKILSAI--------KLKQEYQLCFHKTKQKLKQNPNAKQFDFSEMYIFGKFE 474
+ E++LS I +L Q Y C K K + ++F F +
Sbjct: 360 KGLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFK-DKEPVPWEFPSSLAFSRIN 418
Query: 475 TFHRRLAKIIDIFTTLKTYSVLQDSTIEG-----LEDMATK-YQGIVATIK---KKEYNF 525
+F +R+ I +++ T + L+ + G L + T+ Y + +K +Y+
Sbjct: 419 SFFQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDP 478
Query: 526 LDQRKMDFDQDYEEFCKQTNDLHNELRKFMDVTF---AKIQNTNQALRMLKKFERLNIPN 582
LD +FD+DY +F + DL L F + I+++ + L M +
Sbjct: 479 LDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLIL 538
Query: 583 LGIDDKYQLILENYGADIDMISKLYTKQKYD------PPLARNQPPIAGKILWARQLFHR 636
+ +Y ++LE + A++D LY Q P + +N PP+AG++ W+ +L R
Sbjct: 539 AEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQER 598
Query: 637 IQQPMQLFQ--QHPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWLRQI-EEIHVGLE 693
++ M+ + +HP V+S AEAK + Y+ M ++L ++ W+ + ++ H L
Sbjct: 599 LEVSMKHLKHVEHP-VMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLG 657
Query: 694 ASLLVKAPGTGELFVNFDPQILILFRETECM-AQMGLEVSPLATSLFQKRDRYKRNFSNM 752
L+++ + + VNF ++ + RE + + Q E+ A SLF + + +++ N+
Sbjct: 658 QPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNL 717
Query: 753 KMMLAEYQRVKSKIPAAIEQLIVPHLAKVDEALQPGLAALTWTSLNIEAYLENTFAKIKD 812
++++ Y +K+ + A LI L +D L L W + Y++ + +
Sbjct: 718 ELIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHN 777
Query: 813 LELLLDRVNDLIEFRIDAILEEMSSTPL 840
L+ + + IE I +++ S+ PL
Sbjct: 778 LQNRMQKAKQNIE-GISQAMKDWSANPL 804
>gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 1921 bits (4976), Expect = 0.0
Identities = 1188/3643 (32%), Positives = 1930/3643 (52%), Gaps = 188/3643 (5%)
Query: 1083 ENELQDTLEIASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTIINSTKKEVITSMDCFK 1142
E + D +A + + NY ++ +N +++++ +S+++ + KE D F+
Sbjct: 929 EGLVNDIYNVARLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFE 988
Query: 1143 RYNHIWQKGKEEAIKTFITQS--------------------PLLSEFESQILYFQNLEQE 1182
RY+++W +E +K F+ P L++F+ QI ++ L +E
Sbjct: 989 RYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEE 1048
Query: 1183 IN-AEPEYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIFMLIEEFNK 1241
++ E V G + K AL + + W + RH + + + ++ ++
Sbjct: 1049 VSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARM 1108
Query: 1242 KLNRPIK--DLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKV 1299
L +P+K D D + M L +++E Q + D P++++ LL YG + E K+
Sbjct: 1109 GLTKPLKEGDYDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKL 1168
Query: 1300 DTLHYAWEKLLARAGEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMA-SG 1358
L W A +V+ + LQ + L + F H+F + P + S
Sbjct: 1169 QELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSD 1228
Query: 1359 LKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIYTL 1418
P ++ +++ + + + + + +GG LF +P Y QL +++ LL++++ +
Sbjct: 1229 PNPYKSLNKVFLLKGIMEALSK-----SGG--LFEVPVPDYKQLKACHREVRLLKELWDM 1281
Query: 1419 YNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKKIIDDFSE 1478
V ++ + W ++N+E+++ + +F R L + +K W AF+ L + +
Sbjct: 1282 VVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVIT 1341
Query: 1479 CCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDICISA 1538
+ + + A+ ERHW+++ T + E+ L ++++ L Y++E+ +I A
Sbjct: 1342 SLRAVSELQNPAIRERHWQQLMQATQVKFKMSEET-TLADLLQLNLHSYEDEVRNIVDKA 1400
Query: 1539 VKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEIIANMEDSLMLLGSLLSN 1598
VKE +E+ LK + + W F G ++L+ S+ ++ +ED+ + L +L+ +
Sbjct: 1401 VKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLK--SSEVLVETLEDNQVQLQNLMMS 1458
Query: 1599 RYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGG-DIAKQLPKEAKRFSN 1657
+Y F ++ W Q LS + +I W VQ W +LE++F+G DI QLP +++RF +
Sbjct: 1459 KYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDD 1518
Query: 1658 IDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRF 1717
I++ + +M A + P+VV+ L L L L IC+K+L YLE KRL FPRF
Sbjct: 1519 INQEFKALMEDAVKTPNVVEA-TSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRF 1577
Query: 1718 FFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDRILSIS----SQEGETI 1773
+FVS LL+IL +D + HL +FD++ +KF D+ L + S+E E +
Sbjct: 1578 YFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYM 1637
Query: 1774 ELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLSSFPAQVGLLG 1833
D+ G VEVWLN +L+ S+L I +A +E + +++ +PAQ+
Sbjct: 1638 VFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPRE--QWILDYPAQIW--- 1692
Query: 1834 IQMIWTRDSEEALRNAKFDK---KIMQKTNQAFLELLNTLIDVTTRDLSSTERVKYETLI 1890
WT +E L A+ ++ ++ N+ + LN LI + +L++ +R+K T+
Sbjct: 1693 ----WT--TEVGLAFARLEEGYENAIRDYNKKQISQLNVLITLLMGNLNAGDRMKIMTIC 1746
Query: 1891 TIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQNEFLGCT 1950
TI VH RD+ + M ++S F W Q R ++E+ +I D Y E+LG T
Sbjct: 1747 TIDVHARDV---VAKMIVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNT 1803
Query: 1951 DRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQM 2010
RLVITPLTDRCYITL Q+L + MGGAPAGPAGTGKTETTKD+GR LG V VFNCS+QM
Sbjct: 1804 PRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQM 1863
Query: 2011 DFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDN 2070
D++ G I+KGLAQ+G+WGCFDEFNRI + VLSV A Q+ + + KK+F F G+
Sbjct: 1864 DYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFL-GEI 1922
Query: 2071 VTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVL 2130
+ + P G+F+TMNPGYAGR ELPENLK FR AM+VPD ++I + L + GF++ +L
Sbjct: 1923 IGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLL 1982
Query: 2131 ARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNL 2190
ARKF TLY LC+E LSKQ HYD+GLR I SVL G+ KR +P E ++MR LRD N+
Sbjct: 1983 ARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNI 2042
Query: 2191 SKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFE 2250
K++ +D P+F+ LI DLFP + + + E I + + E L + LKV+QL E
Sbjct: 2043 PKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEE 2102
Query: 2251 TQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKPHREMRMNPKAITAPQMFGRLDVATN 2310
+VRH + +G +G+GK+ + +L + + + + ++PKA+T ++FG ++ T
Sbjct: 2103 LLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPVTR 2162
Query: 2311 DWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMA 2370
+W DG+FST+ R WIILDG +D +WIE+LN+V+DDNK LTLA+ +RIP+
Sbjct: 2163 EWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLN 2222
Query: 2371 PNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFLKKRSPQEAE----ILRQ 2426
+++FE ++ A+PATVSR G+++++ + L W+P++ ++++R Q + IL
Sbjct: 2223 RTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFD 2282
Query: 2427 LYTESFPDLYRFCIQNLEYKMEVLEAFVITQSINMLQGLIPLKEQGGEVSQAHLGRLFVF 2486
Y + D RF + + V E VI + +L+ L+ K + + FVF
Sbjct: 2283 KYLPTCLDKLRFGFKKIT---PVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVF 2339
Query: 2487 ALLWSAGAALE----LDGRRRLELWLRSRPTGTLELPPPAGPGDTAFDYYVAPDGT-WTH 2541
W+ G A+ +D R W + T++ P T FDYY+ PD +
Sbjct: 2340 TCFWAFGGAMFQDQLVDYRVEFSKWWINE-FKTIKFPSQG----TIFDYYIDPDTKKFLP 2394
Query: 2542 WNTRTQEYLYPSDTTPEYGSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIK 2601
W + + D + + LV + +R + + + ++ V+L+G GT K+V++
Sbjct: 2395 WTDKVPSFELDPDVPLQ--ASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMG 2452
Query: 2602 GFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNM 2661
+ + + ++++++ F+ TT M Q +E ++K+ G YGPP KK+ FIDD+NM
Sbjct: 2453 DKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNM 2512
Query: 2662 PIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLK 2721
P ++++G + ++RQ M+ +Y+ K I + Q++A M +P G I RL+
Sbjct: 2513 PEVDKYGTVAPHTLIRQHMDHRHWYDRHKL-TLKDIHNCQYVACM-NPTSGSFTIDSRLQ 2570
Query: 2722 RQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKM 2781
R F +F + P + ++ I+ I H R S ++ ++LV L Q
Sbjct: 2571 RHFCVFAVSFPGQEALTTIYNTILTQHLAF-RSVSMAIQRISSQLVAAALALHQKITATF 2629
Query: 2782 LPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIADRFTVSSDVT 2841
LPT KFHYVFNLRDLS ++QG+L +T+EV+K P DL++LW HE +RV D+ D
Sbjct: 2630 LPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQE 2689
Query: 2842 WFDKALVSLVEEEFGE--EKKLLVDCGIDTYFVDFLRDAPEAAGETSEEADAETPKIYEP 2899
+ ++ ++ F + ++ L I +F + D PK Y P
Sbjct: 2690 TLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGD----------------PK-YVP 2732
Query: 2900 IESFSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVGVGG 2959
+ + L + L L YNE A M++V F DA+ H+ +I+R++ +P+GNALLVGVGG
Sbjct: 2733 VTDMAPLNKLLVDVLDSYNEV--NAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGG 2790
Query: 2960 SGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIK 3019
SGKQSL+RLA++I+G FQITL + Y +L DL Y A + F+ TD+++
Sbjct: 2791 SGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVA 2850
Query: 3020 DESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNENLHDYFMSRVR 3079
+E FL +N++L+SGE+ LF DE++ I S + +K T E +F+ +VR
Sbjct: 2851 EEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMN--DTRETCWKFFIEKVR 2908
Query: 3080 QNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSYDIDCSL 3139
+ L ++LCFSPVG R RA KFPA+++ IDWF WP+DALV+VS FL +
Sbjct: 2909 RQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETE-GIPW 2967
Query: 3140 EIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTL 3199
E+K + M V E Y RR + TPK++L I+ Y+ + +K E+
Sbjct: 2968 EVKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAK 3027
Query: 3200 ANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEV 3259
R+ GL KL+ + V L +L +E EL+ N+ AD +++ V ++A+ K KA
Sbjct: 3028 IERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIA 3087
Query: 3260 QKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLI 3319
+ + + + I ++++ + E L A+PAL A+ AL T+ +++ +++ G PP +
Sbjct: 3088 DQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAV 3147
Query: 3320 MRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLM-TAGNFLQNLQQFPKDTINEEV 3378
+ + V++L KI +KS W+ + +M FL +L++F K+ I E
Sbjct: 3148 VNVTAAVMIL---TAPGGKIPKDKS-----WKAAKIMMGKVDTFLDSLKKFDKEHIPEAC 3199
Query: 3379 IEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQENRHL 3438
++ PY P ++ E + AGLCSW + F+ + +V P + L
Sbjct: 3200 LKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELA 3259
Query: 3439 LAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLAG 3498
A + L + + ++ + A L + + +E+A EK ++A+ + A+ L+ GLA
Sbjct: 3260 EAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLAS 3319
Query: 3499 EKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLND-WRKEMKARK--I 3555
E RW E + F +Q L GDVLL +AF+SY G F +++R+ L+ W + K I
Sbjct: 3320 ENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPI 3379
Query: 3556 PFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIK 3615
P L+ +L D ++ WN QGLP+D +S +N I+ R+PL++D Q QG WIK
Sbjct: 3380 PITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIK 3439
Query: 3616 NKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTGSTF 3675
NK R+EL+ L K + + +E ++S G LLIE++GE +DP LD +L RN IK G
Sbjct: 3440 NKY-RSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKY- 3497
Query: 3676 KVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTE 3735
+K+GDKEV+ FRL + TK NP Y PE+ A+ ++I+F VT GLEDQLL V+ E
Sbjct: 3498 -IKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKE 3556
Query: 3736 KQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEV 3795
+ +LE+ + +L + K +KELED+LL RL++ G+ + D +L+ L TK TA E+
Sbjct: 3557 RPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEI 3616
Query: 3796 TQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSL 3855
+K+ + TEV+IN ARE YRP A R S+LYF++ ++ +N +YQ SL+ F +F+ ++
Sbjct: 3617 EEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAI 3676
Query: 3856 ARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEF 3915
R+ + +R+ N+ + +TY VY Y ARGL+E K +F +T ++ + + E
Sbjct: 3677 QRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVEL 3736
Query: 3916 LTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIWFDK 3975
L++ KA P ++ W + LS++ +F ++ I + K WK +
Sbjct: 3737 DFLLR----FPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVES 3792
Query: 3976 ENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLEKT 4035
E PE+E P + K+ ++L ++R PDR + ++ + MG K+ EG ++ K+
Sbjct: 3793 EAPEKEIFPKEW-KNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKS 3851
Query: 4036 WEESDPRTPLICLLSMGSDPTDSIIALGKRLKI-----ETRYVSMGQGQEVHARKLLQQT 4090
+EES P T + +LS G DP + ALGK+L + VS+GQGQEV A L
Sbjct: 3852 YEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVA 3911
Query: 4091 MANGGWALLQ--------NCHLGLDFMDELMDIIIETELV--HDAFRLWMTTEAHKQ--- 4137
G W +LQ N HL ++ L D +E H+ +R++++ E
Sbjct: 3912 AEKGHWVILQVRGGQHCRNIHLVARWLGTL-DKKLEHYSTGSHEDYRVFISAEPAPSPET 3970
Query: 4138 --FPITLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSGS-QWKPMLYAVAFLHST 4194
P +L+ +IK N+PP G+ A L + +QD L++ + ++K ML+A+ + H+
Sbjct: 3971 HIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAV 4030
Query: 4195 VQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGR 4254
V ERRKFGA GWN Y FN D ++ + N+L+ V W +RY+ GEI YGG
Sbjct: 4031 VAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLE---ANPKVPWDDLRYLFGEIMYGGH 4087
Query: 4255 VTDDYDKRLLNTFAKVWFSENMFGPDFSFYQGYNIPKCSTVDNYLQYIQSLPAYDSPEVF 4314
+TDD+D+RL T+ + M D G+ IP Y +YI +SP ++
Sbjct: 4088 ITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLY 4147
Query: 4315 GLHPNADITYQSKLAKDVLDTILGIQPKDTSGGGDE--TREAVVARLA------------ 4360
GLHPNA+I + + ++ + T+L +QPK+T G +RE L
Sbjct: 4148 GLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLE 4207
Query: 4361 -----------------DDMLEKLPPDYVPFEVKERLQKMGPFQPMNIFLRQEIDRMQRV 4403
DD+LEK+P F + E + K P + QE +RM +
Sbjct: 4208 LRRGGCPGTGFQVKAVLDDILEKIPET---FNMAEIMAKAAEKTPYVVVAFQECERMNIL 4264
Query: 4404 LSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDARIPAWWKKASWISST-LGFWFTELI 4462
+ +R +L EL L + G + ++ ++ D +F +P W ++ S L W+ +L+
Sbjct: 4265 TNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLL 4324
Query: 4463 ERNSQFTSWVFN-GRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKWM 4521
R + +W + P W+ GFFNPQ FLTA+ Q + R N+ W LD M L EVTK
Sbjct: 4325 LRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNE-WPLDKMCLSVEVTKKN 4383
Query: 4522 KDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIYA-ENNTLRDPR 4580
++D++APP EG YVYGL++EGA WD + + E++ K L MPVI I A + +
Sbjct: 4384 REDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKN 4443
Query: 4581 FYSCPIYKKPVRTDLNYIAAVDLRTAQTPEHWVLRGVALLCDV 4623
Y CP+YK +R Y+ +L+T + W+L VALL V
Sbjct: 4444 IYECPVYKTRIRGP-TYVWTFNLKTKEKAAKWILAAVALLLQV 4485
Score = 168 bits (426), Expect = 1e-40
Identities = 148/628 (23%), Positives = 282/628 (44%), Gaps = 50/628 (7%)
Query: 250 LGKIEDCMKVWIKQTEQVLAENN-QLLKEADDVGPRAELEHWKKRLSKFNYLLEQLKSPD 308
L IE + W Q VL++++ Q L + P+ E E W RL + EQL P
Sbjct: 190 LHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDTRLLNLKCIHEQLNRPK 249
Query: 309 VKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLEKCCDPLYSSDPLSMMD 368
V ++ +L AKS + + +T+ EA D V YL L + + +D +
Sbjct: 250 VNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQADFTMLPT 309
Query: 369 AIPTLINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAYITNNGTASIWNQPQDVV 428
I +++ I I++ S YYNT +I + + NQII + +++ P++V+
Sbjct: 310 FIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLS----------PEEVL 359
Query: 429 E------EKILSAI--------KLKQEYQLCFHKTKQKLKQNPNAKQFDFSEMYIFGKFE 474
+ E++LS I +L Q Y C K K + ++F F +
Sbjct: 360 KGLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFK-DKEPVPWEFPSSLAFSRIN 418
Query: 475 TFHRRLAKIIDIFTTLKTYSVLQDSTIEG-----LEDMATK-YQGIVATIK---KKEYNF 525
+F +R+ I +++ T + L+ + G L + T+ Y + +K +Y+
Sbjct: 419 SFFQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDP 478
Query: 526 LDQRKMDFDQDYEEFCKQTNDLHNELRKFMDVTF---AKIQNTNQALRMLKKFERLNIPN 582
LD +FD+DY +F + DL L F + I+++ + L M +
Sbjct: 479 LDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLIL 538
Query: 583 LGIDDKYQLILENYGADIDMISKLYTKQKYD------PPLARNQPPIAGKILWARQLFHR 636
+ +Y ++LE + A++D LY Q P + +N PP+AG++ W+ +L R
Sbjct: 539 AEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQER 598
Query: 637 IQQPMQLFQ--QHPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWLRQI-EEIHVGLE 693
++ M+ + +HP V+S AEAK + Y+ M ++L ++ W+ + ++ H L
Sbjct: 599 LEVSMKHLKHVEHP-VMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLG 657
Query: 694 ASLLVKAPGTGELFVNFDPQILILFRETECM-AQMGLEVSPLATSLFQKRDRYKRNFSNM 752
L+++ + + VNF ++ + RE + + Q E+ A SLF + + +++ N+
Sbjct: 658 QPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNL 717
Query: 753 KMMLAEYQRVKSKIPAAIEQLIVPHLAKVDEALQPGLAALTWTSLNIEAYLENTFAKIKD 812
++++ Y +K+ + A LI L +D L L W + Y++ + +
Sbjct: 718 ELIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHN 777
Query: 813 LELLLDRVNDLIEFRIDAILEEMSSTPL 840
L+ + + IE I +++ S+ PL
Sbjct: 778 LQNRMQKAKQNIE-GISQAMKDWSANPL 804
>gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens]
Length = 4486
Score = 1920 bits (4974), Expect = 0.0
Identities = 1191/3668 (32%), Positives = 1940/3668 (52%), Gaps = 141/3668 (3%)
Query: 1003 KQNSLPIFRASVTLAIPNIVMAPALED-VQQTLNKAVECIIS----VPKGVRQWSSELLS 1057
K PIF A ++LAIP +V P+LE V+ VE +I+ +P V + S + S
Sbjct: 913 KAGLTPIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIPSLVPRLSPQNGS 972
Query: 1058 KKKIQERKMAALQSNEDSDSDVEMGENELQDTLEIASVNLPIPVQTKNYYKNVSENKEIV 1117
Q + D D+ L + ++ + L Q+
Sbjct: 973 PH---------YQVDLDGIPDLANMRRTLMERVQ-RMMGLCCGYQST------------- 1009
Query: 1118 KLVSVLSTIINSTKKEVITSMDCFKRYNHIWQKGK-EEAIKTFITQSP-LLSEFESQILY 1175
S S + +KEV+ F Y HI + E+ ++ I ++P LLS+F+ QI
Sbjct: 1010 --FSQYSYLYVEDRKEVLGQ---FLLYGHILTPEEIEDHVEDGIPENPPLLSQFKVQIDS 1064
Query: 1176 FQNLEQEI-NAEPEYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIFM 1234
++ L +E+ EP V G + + K +L K W ++ +H + N+
Sbjct: 1065 YETLYEEVCRLEPIKVFDGWMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDA 1124
Query: 1235 LIEEFNKKLNRPIK--DLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIA 1292
I++ L + ++ D + M L ++E Q + D P++++ LL Y +
Sbjct: 1125 FIKKSESGLLKKVEKGDFQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELP 1184
Query: 1293 REEIDKVDTLHYAWEKLLARAGEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLN 1352
+++ L W + A V+ ++ LQ + L F + QF+ +
Sbjct: 1185 ETVFKQLEELPEKWNNIKKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKE 1244
Query: 1353 GPMA-SGLKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNL 1411
P + P + D + Q ++ + + LF + Y QL + +K++
Sbjct: 1245 APFRFDSIHPHQMLDARHIEIQQMESTMA---SISESASLFEVNVPDYKQLRQCRKEVCQ 1301
Query: 1412 LQKIYTLYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKK 1471
L++++ V +++++ W +N+E + E +F R L + ++ W AF L+
Sbjct: 1302 LKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFTGLES 1361
Query: 1472 IIDDFSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEI 1531
+ + + + + A+ ERHW ++ TG S + ++ L ++++ L Y++E+
Sbjct: 1362 TVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVSFTMDQDT-TLAHLLQLQLHHYEDEV 1420
Query: 1532 EDICISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEIIANMEDSLML 1591
I A KE +E+ LK++ W F + LL D ++I +ED+ +
Sbjct: 1421 RGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPRTNVPLLCSDE--DLIEVLEDNQVQ 1478
Query: 1592 LGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGG-DIAKQLPK 1650
L +L+ ++Y F ++ W + LS +I W VQ W +LE++F G DI QLP+
Sbjct: 1479 LQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQ 1538
Query: 1651 EAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLEKK 1710
++KRF ID + ++ A ++P+VVQ L + L + +L +C+K+L YL+ K
Sbjct: 1539 DSKRFEGIDIDFKELAYDAQKIPNVVQT-TNKPGLYEKLEDIQGRLCLCEKALAEYLDTK 1597
Query: 1711 RLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDR----ILSIS 1766
RL FPRF+F+S LL+IL + +Q HL +FDN+ ++F L +
Sbjct: 1598 RLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMY 1657
Query: 1767 SQEGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLSSFP 1826
S+E E + +P G VE+WLN +L ++++ + + +E + ++L P
Sbjct: 1658 SKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEKPRE--QWLFDHP 1715
Query: 1827 AQVGLLGIQMIWTRDSEEAL-RNAKFDKKIMQKTNQAFLELLNTLIDVTTRDLSSTERVK 1885
AQV L Q+ WT + A R + + M+ + + L TLI + LS +R K
Sbjct: 1716 AQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQK 1775
Query: 1886 YETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQNE 1945
T+ TI VH RD+ + + + F WL Q R ++++ +I D F+Y E
Sbjct: 1776 IMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYE 1835
Query: 1946 FLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFN 2005
+LG T RLVITPLTDRCYITL Q+L ++M GAPAGPAGTGKTETTKD+GR LG V VFN
Sbjct: 1836 YLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFN 1895
Query: 2006 CSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIF 2065
CS+QMD++ G I+KGLAQ+G+WGCFDEFNRI + VLSV A Q+ I ++ K+ F F
Sbjct: 1896 CSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSF 1955
Query: 2066 TDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFI 2125
G+ +++NP G+F+TMNPGYAGR ELPENLK FR AM+VPD ++I + L + GFI
Sbjct: 1956 L-GEEISLNPSVGIFITMNPGYAGRTELPENLKSLFRPCAMVVPDFELICEIMLVAEGFI 2014
Query: 2126 DNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVL 2185
+ LARKF TLY+LC+E LSKQ HYD+GLR I SVL G+ KR +P E ++MR L
Sbjct: 2015 EAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSL 2074
Query: 2186 RDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKV 2245
RD N+ K++ +D P+F+ LI DLFP + + + P EA + + + + L + LKV
Sbjct: 2075 RDFNIPKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKV 2134
Query: 2246 IQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKPHREMRMNPKAITAPQMFGRL 2305
+QL E VRH + +G +G GK+ + +L + + +NPKA+T ++FG +
Sbjct: 2135 VQLEELLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKRRPVWTDLNPKAVTNDELFGII 2194
Query: 2306 DVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANGD 2365
+ AT +W DG+FS++ R+ WI+LDG +D +WIE+LN+V+DDNK LTLA+ +
Sbjct: 2195 NPATGEWKDGLFSSIMRELANITHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNE 2254
Query: 2366 RIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFLKKRSPQEAEILR 2425
RIP+ P K++FE ++ A+PATVSR G+++++ + L W+P + +++KR E + R
Sbjct: 2255 RIPLNPTMKLLFEISHLRTATPATVSRAGILYINPADLGWNPPVSSWIEKR---EIQTER 2311
Query: 2426 QLYTESFPDLYRFCIQNLEYKME----VLEAFVITQSINMLQGLIPLKEQGGEVSQAHLG 2481
T F C+ L + + + E ++ ++L+ L+ ++ + +
Sbjct: 2312 ANLTILFDKYLPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLECLLTTEDIPADCPKEIYE 2371
Query: 2482 RLFVFALLWSAGAALE----LDGRRRLELWLRSRPTGTLELPPPAGPGDTAFDYYVAPD- 2536
FVFA +W+ G A+ +D R W + T++ P T FDYY+ P+
Sbjct: 2372 HYFVFAAIWAFGGAMVQDQLVDYRAEFSKWWLTE-FKTVKFPSQG----TIFDYYIDPET 2426
Query: 2537 GTWTHWNTRTQEYLYPSDTTPEYGSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQGTAK 2596
+ W+ ++ + D + LV + +R + ++ + + + V+L+G GT K
Sbjct: 2427 KKFEPWSKLVPQFEF--DPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGK 2484
Query: 2597 TVIIKGFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKMTVFI 2656
+V++ ++ DPE +++K++ F+ TT M Q +E ++K+ G YGPP KK+ FI
Sbjct: 2485 SVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFI 2544
Query: 2657 DDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDI 2716
DD+NMP ++ +G + I+RQ ++ +Y+ K I ++Q+++ M +P G I
Sbjct: 2545 DDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKL-SLKEITNVQYVSCM-NPTAGSFTI 2602
Query: 2717 PQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQM 2776
RL+R FS+F + P ++ I+ +I H F ++ S+ L+ L Q
Sbjct: 2603 NPRLQRHFSVFVLSFPGADALSSIYSIILTQH-LKLGNFPASLQKSIPPLIDLALAFHQK 2661
Query: 2777 TKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIADRFTV 2836
LPT KFHY+FNLRD + ++QG+L ++ E +K DL++L+ HE RV D+
Sbjct: 2662 IATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRDKMVE 2721
Query: 2837 SSDVTWFDKALVSLVEEEFGEEKKLLVDCGIDTYFVDFLRDAPEAAGETSEEADAETPKI 2896
D FDK ++++ F + + + + F E PK
Sbjct: 2722 EKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYCHFANGIGE-------------PK- 2767
Query: 2897 YEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVG 2956
Y P++S+ L + L L+ +NE MD+V F DAM H+ I+R++ +P+GNALLVG
Sbjct: 2768 YMPVQSWELLTQTLVEALENHNEV--NTVMDLVLFEDAMRHVCHINRILESPRGNALLVG 2825
Query: 2957 VGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDN 3016
VGGSGKQSLTRLA+FI+ FQITL + Y + DL L AG + F+ TD
Sbjct: 2826 VGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDA 2885
Query: 3017 EIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNENLHDYFMS 3076
++ DE FL +N++L+SGE+ +L++ DE++ I S++ + +K + + EN +F+
Sbjct: 2886 QVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQ--GLVDNRENCWKFFID 2943
Query: 3077 RVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSYDID 3136
R+R+ L + LCFSPVG K R R+ KFPA+++ I WF WP+ AL +VS FL + +
Sbjct: 2944 RIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTE-G 3002
Query: 3137 CSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEV 3196
+K+ + + M V + Y +R + TPKS+L FI+ Y+ + E+
Sbjct: 3003 IEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKEL 3062
Query: 3197 RTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVK 3256
+ R+ GL KL S V L +L A+E EL+ N+ AD +++ V ++ + K
Sbjct: 3063 KCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREK 3122
Query: 3257 AEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPP 3316
A + + + I+ + + + EE L A+PAL A+AAL T+ +++ +++ G PP
Sbjct: 3123 AMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPP 3182
Query: 3317 HLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQES-LKLMTAGNFLQNLQQFPKDTIN 3375
+ + V++L + K SW+ + + + FL +L F K+ I+
Sbjct: 3183 LAVSNVSAAVMVLMAPRGRVPK--------DRSWKAAKVTMAKVDGFLDSLINFNKENIH 3234
Query: 3376 EEVIEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQEN 3435
E ++ + PY + P++N E AGLCSW + F+ + +V P + L
Sbjct: 3235 ENCLKAIRPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATA 3294
Query: 3436 RHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISG 3495
A + L +A++ L + A +E+A +K ++AE + A+ L+ G
Sbjct: 3295 DLTAAQEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGG 3354
Query: 3496 LAGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLN-DWRKEMKARK 3554
LA E RW + Q F Q + L GD+LL TAF+SY G F +++R LL+ WR + K
Sbjct: 3355 LASENVRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLK 3414
Query: 3555 --IPFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKI 3612
IP L+ ML+D ++ W +GLP D +S++N I+ R+PL++DPQ QG
Sbjct: 3415 TPIPVTPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIK 3474
Query: 3613 WIKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTG 3672
WIKNK +L++T + K + +E +L G +LIE++ E +DP L +L R IK G
Sbjct: 3475 WIKNKYG-EDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKG 3533
Query: 3673 STFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVI 3732
+K+GDKE + FRL + TKL NP Y PE+ A+ ++I+FTVT GLEDQLL V+
Sbjct: 3534 RF--IKIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVV 3591
Query: 3733 LTEKQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTA 3792
E+ +LE+ ++ L + K +K LED+LL RL+S G+ + + L+ L TK+TA
Sbjct: 3592 SMERPDLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTA 3651
Query: 3793 EEVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFD 3852
EV +K++ + TEV+IN ARE YRP A R S+LYF++ ++ ++ MYQ SL+ F +F
Sbjct: 3652 AEVEKKVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQ 3711
Query: 3853 LSLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKH 3912
++ R+ +R+AN+I+ +T+ VY+Y RGL+E K + LT +I + V
Sbjct: 3712 KAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNA 3771
Query: 3913 EEFLTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIW 3972
E L++ ++ P +++ W + LS + +FS++ I + K WK +
Sbjct: 3772 VELDFLLRS----PVQTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKF 3827
Query: 3973 FDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDL 4032
+ E PE+E LP + K+ +RL ++R+ PDR R ++ + +G KY G LD
Sbjct: 3828 VESECPEKEKLPQEW-KNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDF 3886
Query: 4033 EKTWEESDPRTPLICLLSMGSDPTDSIIALGKRL-----KIETRYVSMGQGQEVHARKLL 4087
++EES P TP+ +LS G DP + + G++L VS+GQGQEV A L
Sbjct: 3887 ATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAAL 3946
Query: 4088 QQTMANGGWALLQNCHLGLDFMDELMDIIIE-TELVHDAFRLWMTTEAHKQ-----FPIT 4141
G W +LQN HL ++ L + E +E H FR++M+ E P
Sbjct: 3947 DLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQG 4006
Query: 4142 LLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDV-SSGSQWKPMLYAVAFLHSTVQERRK 4200
+L+ SIK N+PP G+ A L + +QD L++ S +++K +L+A+ + H+ V ERRK
Sbjct: 4007 ILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRK 4066
Query: 4201 FGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDDYD 4260
FG GWN Y FN D +V + N L + V + +RY+ GEI YGG +TDD+D
Sbjct: 4067 FGPQGWNRSYPFNTGDLTISVNVLYNFL---EANAKVPYDDLRYLFGEIMYGGHITDDWD 4123
Query: 4261 KRLLNTFAKVWFSENMFGPDFSFYQGYNIPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNA 4320
+RL T+ + M + S G+ +P + Y QYI + +SP ++GLHPNA
Sbjct: 4124 RRLCRTYLGEFIRPEMLEGELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNA 4183
Query: 4321 DITYQSKLAKDVLDTILGIQPKDTSG--GGDETREAVVARLADDMLEKLPPDYVPFEVKE 4378
+I + ++ ++ + T+L +QP+D+ G TRE V L +++LE++ + F + E
Sbjct: 4184 EIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEILERVTDE---FNIPE 4240
Query: 4379 RLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDA 4438
+ K+ P + QE RM + ++ +L EL+L + G + M+ ++ + + ++
Sbjct: 4241 LMAKVEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFD 4300
Query: 4439 RIPAWWKKASWISST-LGFWFTELIERNSQFTSWVFN-GRPHCFWMTGFFNPQGFLTAMR 4496
+P W + ++ S+ L WF +L+ R + +W + P W+TGFFNPQ FLTA+
Sbjct: 4301 MVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIM 4360
Query: 4497 QEITRANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESK 4556
Q R N+ W LD M L ++TK +++ +PP EG Y++GL++EGA WD + + E+K
Sbjct: 4361 QSTARKNE-WPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAK 4419
Query: 4557 PKVLFELMPVIRIYAENNTLRDPR-FYSCPIYKKPVRTDLNYIAAVDLRTAQTPEHWVLR 4615
K L MPV+ I A +D R YSCP+YK R Y+ +L+T + P WVL
Sbjct: 4420 LKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRGP-TYVWTFNLKTKENPSKWVLA 4478
Query: 4616 GVALLCDV 4623
GVALL +
Sbjct: 4479 GVALLLQI 4486
Score = 183 bits (465), Expect = 3e-45
Identities = 169/746 (22%), Positives = 318/746 (42%), Gaps = 61/746 (8%)
Query: 118 GNDVALTGV-CVFFIRTDPSKAITPDNIHQEVSFNMLDAADGGLLNSVRRLLSDIFIPAL 176
G + L G +FF+RT P PD+ V L AA L + L S++ +P L
Sbjct: 90 GPESGLAGAKALFFLRTGPEPP-GPDSFRGAVVCGDLPAAP---LEHLAALFSEVVLPVL 145
Query: 177 RATSHGWGELEGLQDAANIRQEFLSSLEGFVNVLSGAQESLKEKVNL---RKCDILELKT 233
E L I ++ LS E +K K L + +E
Sbjct: 146 A------NEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQVKGKTLLPLPAGSEKMEFAD 199
Query: 234 LKEPTDYLTLANNPETLGKIEDCMKVWIKQTEQVLA-ENNQLLKEADDVGPRAELEHWKK 292
K T ++ + + IE + W Q + VL E++Q L + ++ P+ ELE WK
Sbjct: 200 SKSETVLDSI--DKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQGENPTPKVELEFWKS 257
Query: 293 RLSKFNYLLEQLKSPDVKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLE 352
R Y+ QL++ V+ + +L +S ++ M + A EA+D +L L+
Sbjct: 258 RYEDLKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVVAALAEAQDIHVHLIPLQ 317
Query: 353 KCCDPLYSSDPLSMMDAIPTLINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAYI 412
+ + L +++ + + L++ + +I++ Y + ++T L ++ N +I Y+
Sbjct: 318 RHLEALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTVLLQEICNLLIQQASNYL 377
Query: 413 TNNGTASIWNQPQDVVEEKILSAIK-----------LKQEYQLCFHKTKQKLKQNPNAKQ 461
+ P+D++ ++ + + KQE+Q K+N K+
Sbjct: 378 S----------PEDLLRSEVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFKENQEVKE 427
Query: 462 FDFSEMYIFGKFETFHRRLAKIIDIFTTLKTYSVLQDSTIEG---------LEDMATKYQ 512
+DF +F + + F +L + + T + L G ++ M ++Q
Sbjct: 428 WDFQSSLVFVRLDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQQMHEEFQ 487
Query: 513 GIVATIKKKEYNFLDQRKMDFDQDYEEFCKQTNDLHNELRKFMDVTFAKIQNTNQALRML 572
+ + + L + DF+ D EF ++ DL L F A ++L
Sbjct: 488 EMYRLLSGSSSDCLYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGLEHAFKLL 547
Query: 573 K-KFERLNIPNLGID--DKYQLILENYGADIDMISKLYTKQKYD------PPLARNQPPI 623
L P + D DKY ++++ + D+D + +Y++ + P+ +N P +
Sbjct: 548 DIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPVHKNMPTV 607
Query: 624 AGKILWARQLFHRIQQPMQLFQQ--HPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAW 681
AG + WA++L RIQ P F + HP + +AE K + + Y M +L ++E + W
Sbjct: 608 AGGLRWAQELRQRIQGPFSNFGRITHPC-MESAEGKRMQQKYEDMLSLLEKYETRLYEDW 666
Query: 682 LRQI-EEIHVGLEASLLVKAPGTGELFVNFDPQILILFRETECMAQMGLEVSP-LATSLF 739
R + E+ L LL + P T E+ +NF+PQ++ + +E + ++ P A ++F
Sbjct: 667 CRTVSEKSQYNLSQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKHMPETAAAMF 726
Query: 740 QKRDRYKRNFSNMKMMLAEYQRVKSKIPAAIEQLIVPHLAKVDEALQPGLAALTWTSLNI 799
RD Y++ +N+++M Y +V + L+ L +D L+ L W + I
Sbjct: 727 SSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLNWKTEGI 786
Query: 800 EAYLENTFAKIKDLELLLDRVNDLIE 825
Y+ + I DLE + + D +E
Sbjct: 787 CDYVTEITSSIHDLEQRIQKTKDNVE 812
>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
Length = 4024
Score = 1918 bits (4968), Expect = 0.0
Identities = 1213/3682 (32%), Positives = 1907/3682 (51%), Gaps = 202/3682 (5%)
Query: 1076 DSDVEMGENELQDTLEI---------ASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTI 1126
D+D E EL D ++I +V+ V+TK Y K S++K +L+ I
Sbjct: 409 DNDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLKPIILNEI 468
Query: 1127 INSTK---KEVITS--------MDCFKRYNHIWQKGKEEAIKTFITQSPLLSEFESQILY 1175
+++ K KEVI + + +Y+ + + E + F+ ++ + +I
Sbjct: 469 VDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITRKAERDVDNFLAENHSYEKIIDEICK 528
Query: 1176 FQNLEQEINAEPEYVCVGSIAL--YTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIF 1233
+Q L +EI +Y + +I L + + + A K ++ G+ K +R E
Sbjct: 529 YQKLIEEI----QYTSIKTIRLGMFEMHCEELIRALVKRADIICGKLLAKMFRDHQEVNT 584
Query: 1234 MLIEEFN----KKLNRPIKDLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGL 1289
L +EF K L+ P + + + K + I ++ ++ + A L Y
Sbjct: 585 RLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVN 644
Query: 1290 LIAREEIDKVDTLHYAWEKLLARAGE-----VQNKLVSLQPSFK---KELISAVEVFLQD 1341
+ +++ + W + E ++ K+ Q K + + +E + +
Sbjct: 645 FSPADM--RLNNSVFQWYGRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQ 702
Query: 1342 CHQFYLDYDLNGPMASGLKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQ 1401
+FY DL K Q + +L + ++ + + EE FG + YPQ
Sbjct: 703 SEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQ-------FNAEEEAFGWLPSVYPQ 755
Query: 1402 LLEIKKQLNLLQKIYTLYNSVIETVNSYYDILWSEVNIEKINNELLE-----FQNRCRKL 1456
+I+ LN + LY + +E ++Y W+E K+N + +E + KL
Sbjct: 756 RKKIQDGLNPYLR---LYETAVEFSSNYR--AWTEGPYHKVNPDQVEADIGNYWRGLYKL 810
Query: 1457 PRALKDWQAFLDL-KKI---IDDFSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNE 1512
+ D L + KK+ ++DF + PL++ + + + RHWE ++ + G+ L ++
Sbjct: 811 EKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDD 870
Query: 1513 SFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELL 1572
S + + ++ L Y + E I +A KE +E+ ++++I EWD F S++ G +
Sbjct: 871 S-TVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRETGTFI 929
Query: 1573 LRGDSTSEIIANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLW 1632
L S EI ++D ++ ++ + + P++ Q+++W L +I++ W+ VQ W
Sbjct: 930 LA--SVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATW 987
Query: 1633 IYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHL 1692
+YLE +F DI Q+P+E +RF+ +DK+W IM + V+ D L + L
Sbjct: 988 LYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRML-ERLKKS 1046
Query: 1693 LDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSV 1752
+ LE+ K L YLEKKRL FPRFFF+S+ LLEIL + D +Q HL F+ I V
Sbjct: 1047 NELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKV 1106
Query: 1753 KFHEKIYDRILSISSQEGETIELDKPVM---AEGNVEVWLNSLLEESQSSLHLVIRQAAA 1809
+F E + I + S EGE +EL + + A G VE WL L +S+H V A
Sbjct: 1107 EFTETL--DITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDAT- 1163
Query: 1810 NIQETGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEALRNAKFDKKIMQKTNQAFLELLNT 1869
T ++ ++ +P Q L Q+ WT++ + A+ K +++ + ++
Sbjct: 1164 -FAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAI---PMGIKALEQYLKTCNRQIDD 1219
Query: 1870 LIDVTTRDLSSTERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSD 1929
++ + LS RV L+ + VH RD+ L +I DFEWL Q R+Y+ E+
Sbjct: 1220 IVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENH- 1278
Query: 1930 KMMIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTET 1989
+ + + Y E+LG + RLVITPLTDRCY TL AL + +GGAP GPAGTGKTET
Sbjct: 1279 -LETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTET 1337
Query: 1990 TKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQI 2049
TKD+ + + K VVFNCSD +D+ LG+ FKGL G+W CFDEFNRIDL VLSV AQQI
Sbjct: 1338 TKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQI 1397
Query: 2050 SIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVP 2109
I +F +G + ++P +F+TMNPGYAGR ELP+NLK FR+VAMMVP
Sbjct: 1398 LTIQRGINAGADILMF-EGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVP 1456
Query: 2110 DRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAK 2169
D +I + L SCGF+ L+ K Y+LC EQLS Q HYD+G+R + SVL G K
Sbjct: 1457 DYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLK 1516
Query: 2170 RANPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQ 2229
P + E +++R + D+NL K + D PLF + DLFP + L K Y +L AAI
Sbjct: 1517 LKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDN 1576
Query: 2230 VEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMTD-CGKPHRE 2288
L + K++Q++E VRHG M +G GKT+ L A+ D C K E
Sbjct: 1577 CASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLME 1636
Query: 2289 MR------MNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVD 2342
+NPK++T Q++G+ D +++W+DG+ + +R + + W+I DGPVD
Sbjct: 1637 ENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPVD 1696
Query: 2343 AIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSI 2402
A+WIEN+N+VLDDNK L L +G+ I M+P +IFEP +++ ASPATVSR GM++M +
Sbjct: 1697 AVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHM 1756
Query: 2403 LDWSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQNLEYKMEVLEAFVITQSINML 2462
L W P++ ++ + I ++ F + ++ + + L T + L
Sbjct: 1757 LGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSL 1816
Query: 2463 QGLIP-----------LKEQGGEVSQAHLGRLFVFALLWSAGAALELDGRRRLELWLR-- 2509
LI LKE+ + + L +F+F+L+WS GA+ D R + LR
Sbjct: 1817 MNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNKILREL 1876
Query: 2510 ------------------SRPTGTLELPPPAGPGDTAFDYYVAPDGT--WTHWNTRTQEY 2549
+ T + L P T +DY +G W W + +E
Sbjct: 1877 MESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIKKLKE- 1935
Query: 2550 LYPSDTTPEYGSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIKGFM-SKYD 2608
P + I+VP +D +R L++ + K + +G GT K+V I F+ ++ +
Sbjct: 1936 APPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLN 1995
Query: 2609 PECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNMPIINEWG 2668
E + +NFS+ TT Q + S +DKR +GPP GK+M VF+DDVNMP +G
Sbjct: 1996 KEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPAREVYG 2055
Query: 2669 DQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFN 2728
Q E++RQ ++ +Y+L K +VDIQ + AM PGGGRN + R R F+I
Sbjct: 2056 AQPPIELLRQWLDHWNWYDL-KDCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHFNIIT 2114
Query: 2729 CTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKF 2788
S+ S+ IF I H F +E D T++V T L++ +LPTPAK
Sbjct: 2115 INEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKS 2174
Query: 2789 HYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIADRFTVSSDVTWFDKALV 2848
HY+FNLRD SRV QG+ + E + + +LW HE RV DR ++D +W +
Sbjct: 2175 HYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLINYIQ 2234
Query: 2849 SLVEEEFGEEKKLLVDCGIDTYFVDFLRDAPEAAGETSEE--ADAETPKI----YEPIES 2902
++ E+ L +DF D A + D PK Y I
Sbjct: 2235 EILRNYMYEDFHELFQR------LDFDNDGMVEADDLRSLMFCDFHDPKREDTNYREIAD 2288
Query: 2903 FSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVGVGGSGK 2962
+L+ + + L+ YN +I M++V F A+ H+ +ISR+++ P+ +ALLVGVGGSG+
Sbjct: 2289 VDNLRMIVEIHLEEYN-NISKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGR 2347
Query: 2963 QSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDES 3022
QS+TRLA+ +A Y FQ+ +++ Y+T+ EDLKV+ R + F+FTD +IK+ES
Sbjct: 2348 QSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEES 2407
Query: 3023 FLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNEN---LHDYFMSRVR 3079
FLE ++N+L++GE+ NLFA DE EI D + ++ + T+ + L + F+ R
Sbjct: 2408 FLEDVSNLLNAGEIPNLFALDEKQEI-CDKMRQLDRQRDKTKQTDGSPIALFNMFIDHCR 2466
Query: 3080 QNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSYDIDCSL 3139
LH+VL SP+G+ FRNR KFPAL++ CTIDWF WP+DAL AV+ FL +I+ S
Sbjct: 2467 SQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLE--EIEMSE 2524
Query: 3140 EIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTL 3199
EI+ + SF + +F +R +VTP SYL I +K + +K EV +
Sbjct: 2525 EIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSEVMKM 2584
Query: 3200 ANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKAD----MVLKEVTMKAQAAEKV 3255
R GLEKL AS VA + ELEA +L+VA+ + D M+ KE A+ + V
Sbjct: 2585 KKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKTEKIV 2644
Query: 3256 KAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRP 3315
KA+ + QA+ KD+ A+ L A P LE A AAL T+ DI V+++ P
Sbjct: 2645 KADETIANE--QAMASKAIKDECDAD--LAGALPILESALAALDTLTAQDITVVKSMKSP 2700
Query: 3316 PHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPS-WQESLKLMTAGNFLQNLQQFPKDTI 3374
P + +M+ + +L K + + W + +L+ FLQ+L ++ KD I
Sbjct: 2701 PAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNI 2760
Query: 3375 NEEVIEFLSP-YFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQ 3433
+ + Y PD+ E + GLC W AM S+ + K V P K L
Sbjct: 2761 PPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAA 2820
Query: 3434 ENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLI 3493
E +AM L+K QA L + Q +L +Q E +K L + C K++ A LI
Sbjct: 2821 EGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLI 2880
Query: 3494 SGLAGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLNDWRKEMKAR 3553
GL GEK RW+ + E L GD+L+++ ++Y G F +R +W K R
Sbjct: 2881 GGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGR 2940
Query: 3554 KIPFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIW 3613
IP + +L L +A TI WN+ GLP+D SI NGII+ A R+PL+IDPQ+Q W
Sbjct: 2941 DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKW 3000
Query: 3614 IKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTGS 3673
IKN E N L + L+ + LE+ + G P+L+E+VGEELDP L+ +L + K G
Sbjct: 3001 IKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGG 3060
Query: 3674 TFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVIL 3733
+ +++GD ++ FR YITTKL NP Y PE S + ++++F +T +G++DQLLG V+
Sbjct: 3061 STCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVA 3120
Query: 3734 TEKQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAE 3793
E+ +LE+E+ L+ NKR++KE+ED +L L+S++G+++EDE+ I +LS++K A
Sbjct: 3121 QERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALAN 3180
Query: 3794 EVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDL 3853
E++QK E++ ETE +I++ R YRP+A SIL+F + ++ + MYQ SL F+ LF L
Sbjct: 3181 EISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFINLFIL 3240
Query: 3854 SLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHE 3913
S+ S KS I +KR+ + +H TY +Y R L+E+ K LF+ LT+ + + +
Sbjct: 3241 SIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKA 3300
Query: 3914 EFLTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIWF 3973
E+ L+ GG LD W+ +W + L L F + + R + WK +
Sbjct: 3301 EWRFLLTGGIGLDNPYA--NLCTWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVY 3358
Query: 3974 DKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLE 4033
D P E P ++ + F+R+L+IR PD+ I +++I++ +G + E DL
Sbjct: 3359 DSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLA 3418
Query: 4034 KTWEESDPRTPLICLLSMGSDPTDSIIAL-------GKRLKIETRYVSMGQGQEVHARKL 4086
K + +S+ PLI +LS G+DP +++ G +L +S+GQGQ A K+
Sbjct: 3419 KAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLS----SLSLGQGQGPIAMKM 3474
Query: 4087 LQQTMANGGWALLQNCHLGLDFMDELMDII--IETELVHDAFRLWMTTEAHKQFPITLLQ 4144
L++ + G W +LQNCHL +M L + + E H FR+W+T+ FP+++LQ
Sbjct: 3475 LEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVLQ 3534
Query: 4145 MSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSG----------SQWKPMLYAVAFLHST 4194
+K N+ P+GLRA + R+Y L+D S ++K +LY + F H+
Sbjct: 3535 NGVKMTNEAPKGLRANIIRSY------LMDPISDPEFFGSCKKPEEFKKLLYGLCFFHAL 3588
Query: 4195 VQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGR 4254
VQERRKFG LGWNIPYEFN+ D +VQ + L+ + + + +RYM GE YGGR
Sbjct: 3589 VQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYE---ELPYEALRYMTGECNYGGR 3645
Query: 4255 VTDDYDKRLLNTFAKVWFS-ENMFGPDFSFYQG--YNIPKCSTVDNYLQYIQSLPAYDSP 4311
VTDD+D+R L + +F+ E + D+ F Y +P +Y++Y ++LP +P
Sbjct: 3646 VTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAP 3705
Query: 4312 EVFGLHPNADITYQSKLAKDVLDTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDY 4371
E+FG++ NADIT + + D IL Q + ++G G ++ + VV +A D+L KLP ++
Sbjct: 3706 EIFGMNANADITKDQSETQLLFDNILLTQSR-SAGAGAKSSDEVVNEVASDILGKLPNNF 3764
Query: 4372 VPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDA 4431
E R Q MN L QE+ R ++L +R + ++ AI G +MS +L +
Sbjct: 3765 -DIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEV 3823
Query: 4432 LDCMFDARIPAWWKKASWIS-STLGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQG 4490
+ + + +IP W S+ S LG + + + R W G P FW++GFF Q
Sbjct: 3824 VSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQA 3883
Query: 4491 FLTAMRQEITRANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNM 4550
FLT +Q R + + +L + + PP +GV+++GL+L+GA W+++
Sbjct: 3884 FLTGAQQNYARK---YTIPIDLLGFDYEVMEDKEYKHPPEDGVFIHGLFLDGASWNRKIK 3940
Query: 4551 KLIESKPKVLFELMPVIRIY-AENNTLRDPRFYSCPIYKKPVRTDL--------NYIAAV 4601
KL ES PK+L++ +PV+ + + + Y P+YK R + N++ A+
Sbjct: 3941 KLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAM 4000
Query: 4602 DLRTAQTPEHWVLRGVALLCDV 4623
L + Q EHW+ RGVALLC +
Sbjct: 4001 TLPSDQPKEHWIGRGVALLCQL 4022
>gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]
Length = 4158
Score = 1892 bits (4902), Expect = 0.0
Identities = 1167/3742 (31%), Positives = 1938/3742 (51%), Gaps = 214/3742 (5%)
Query: 1004 QNSLPIFRASVTLAIPNIVMAPALED----VQQTLNKAVECIISVPKGVRQWSSELLSKK 1059
++ +P+F + L + +++ P+LED + +N ++SVP V + +
Sbjct: 507 ESLIPMFLTELMLTVQSLLFEPSLEDFLDGILGAVNHCQNTVLSVPNLVPDSYFDAFTSP 566
Query: 1060 KIQERKMAALQSNEDSDSDVEMGENELQDTLEIASVNLPIPVQTKNYYKNVSENKEIVKL 1119
I + S + V + KN++ +S+ KE ++
Sbjct: 567 YINNKLEGKTCGTGPSLAAVFEDD--------------------KNFHTIISQIKETIQA 606
Query: 1120 VSVLSTIINSTKKEVITSMDCFKRYNHIWQKGKEEAIKTFITQSPLLSEFESQILYFQNL 1179
+ I +T F+++ +++ + ++ Q P ++ F Q+ +
Sbjct: 607 AFESARIYAAT----------FEKFQIFFKENESLDLQALKLQEPDINFFSEQLEKYHKQ 656
Query: 1180 EQEINAEPEYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIFMLIEEF 1239
++ A VG + + T L+ L + V+ ++ + +++ I ++
Sbjct: 657 HKDAVALRPTRNVGLLLIDTRLLREKLIPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDA 716
Query: 1240 NKKLNRPIKDLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKV 1299
KL + ++ L EI+E S++ + + + Y L+ +Y + E+
Sbjct: 717 EYKLEFVPTTTTEYVHSLLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAVF 776
Query: 1300 DTLHYAWEKLLARAGEVQNKLVSLQPSFKK---ELISAVEVFLQDCHQFYLDYDLNGPMA 1356
T+ ++A + + + S K+ L S +E + ++ L P
Sbjct: 777 ATMK---PSIVAVRNAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVKLQ--AQDPQI 831
Query: 1357 SGLKPQEASDRLIM--FQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQK 1414
+ + RLI+ Q+ ++ ++ Y ++ F + +++ L E+ +L L Q
Sbjct: 832 LDISADQDKIRLILNNLQSVLADLQKRAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQL 891
Query: 1415 IYTLYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKKIID 1474
++ ++ + + + ++ E +N ++ ++ +L + L LK ++
Sbjct: 892 LWDSFSEWDKLQQEWLKSKFDCLDPEVLNGQVSKYAKFVTQLEKGLPPNSVVPQLKYKVE 951
Query: 1475 DFSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDI 1534
E P++ + + + RHW I +L L + + + + +EI+DI
Sbjct: 952 KMKEKLPVIIDLRNPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDFGQEIQDI 1011
Query: 1535 CISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEIIANMEDSLMLLGS 1594
A E +E LK+V + W F + ++ + G T +I ++DS + + +
Sbjct: 1012 SGQASGEAALEAILKKVEDSWKTTEFVILPHRDSKDVFILG-GTDDIQVLLDDSTINVAT 1070
Query: 1595 LLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGGDIAKQLPKEAKR 1654
L S+RY P K ++ +W + L+ +E W+T Q W+YLE++F DI +QLP EAK
Sbjct: 1071 LASSRYLGPLKTRVDEWQKQLALFNQTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKM 1130
Query: 1655 FSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPH--LLDQLEICQKSLTGYLEKKRL 1712
F +DKSW +IM + + +P+ ++ L + LLDQ+ QK L YLE KR+
Sbjct: 1131 FLQVDKSWKEIMRKVNRLPNALRAATQPGLLETFQNNNALLDQI---QKCLEAYLESKRV 1187
Query: 1713 CFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFH----------------E 1756
FPRF+F+S+ LLEIL Q + +Q HL FD+I ++F E
Sbjct: 1188 IFPRFYFLSNDELLEILAQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPE 1247
Query: 1757 KIYDR-ILSISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETG 1815
K+Y IL++ S EGE + L K + A GNVE WL + E +SL + + A A+ Q G
Sbjct: 1248 KVYTNDILAMLSPEGERVSLGKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIADYQ--G 1305
Query: 1816 FQLTEFL-SSFPAQVGLLGIQMIWTRDSEEALRNAKFDK-KIMQKTNQAFLELLNTLIDV 1873
T+++ + P+QV L Q++W RD E L + + ++ + E LN L +
Sbjct: 1306 KLRTDWVVAGHPSQVILTVSQIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNALAAI 1365
Query: 1874 TTRDLSSTERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMI 1933
L R LITI VH RDI +L +++ F+W +Q R+Y++ D D +
Sbjct: 1366 VQGSLPKLHRNILTALITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLDNCVA 1425
Query: 1934 HITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDM 1993
+ + Y E+LG RLVITPLTDRCY+ L AL + +GGAPAGPAGTGKTETTKD+
Sbjct: 1426 RMALSQYTYGYEYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDL 1485
Query: 1994 GRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIIL 2053
+ L VVFNCSD +D++ +GR F GLAQSG+W CFDEFNRID+ VLSV AQQ+ I
Sbjct: 1486 AKALAIQCVVFNCSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIR 1545
Query: 2054 TCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQI 2113
K F+F +G + + F+TMNPGYAGR ELP+NLK FR AMMVP+ +
Sbjct: 1546 NAKAAKLSRFMF-EGREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYAL 1604
Query: 2114 IIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANP 2173
I V L S GF + +LARK +YKLC EQLS+Q HYDFG+R + SVL G+ KR NP
Sbjct: 1605 IAEVILYSEGFESSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENP 1664
Query: 2174 MDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEA 2233
E +++R L+D NL K + +D LF +I DLFP + + + Y L++ I +
Sbjct: 1665 DLNEDVVLIRALQDSNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQ 1724
Query: 2234 GLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKPHREMR--- 2290
L KVIQ +ET VRHG+M +GP+G GKTT L + + K E
Sbjct: 1725 NLQPEMCMVRKVIQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGIENSFYQ 1784
Query: 2291 ------MNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAI 2344
+NPK+IT +++G ++ T +W DG+ + R + +H WII DGPVDA+
Sbjct: 1785 AVKTYVLNPKSITMGELYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDAL 1844
Query: 2345 WIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILD 2404
WIEN+N+VLDDNK L LAN +RI + P ++FE ++ ASPATVSR GMVF+ L
Sbjct: 1845 WIENMNTVLDDNKMLCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELK 1904
Query: 2405 WSPI----LEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQNLEYKMEVLEAFVITQSIN 2460
W P ++G KK + + E + L+ + F + + ++ +T
Sbjct: 1905 WMPYVKTWMKGISKKLTEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTTLCC 1964
Query: 2461 MLQGLIPLKEQGGEVSQAH------LGRLFVFALLWSAGAALELDGRRRLELWLRSRPTG 2514
+L+ LI L + G ++ L + FVF LWS G L + + ++R++
Sbjct: 1965 LLESLI-LGKDGVNLAMEQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFDD 2023
Query: 2515 TLELPPPAGPGDTAFDYYVAPDGTWTHWNTRTQEYLYPSDTTPEYGSILVPNVDNVRTDF 2574
+ P GD + W + Y D + +LVP D VR +
Sbjct: 2024 NPDARLP-NSGDLWSIHMDFDTKRLDPWERIIPTFKYNRDVP--FFEMLVPTTDTVRYGY 2080
Query: 2575 LIQTIAKQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKS-LNFSSATTPLMFQRTIE 2633
L++ + +VL G G K+VI KG ++K + LNFS+ T+ Q IE
Sbjct: 2081 LMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIE 2140
Query: 2634 SYVDKRMGTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGE 2693
S ++++ G P K++ +F+DD+NMP ++ +G Q E++RQ + GFY+ K
Sbjct: 2141 SKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLF- 2199
Query: 2694 FTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQR 2753
+ I D+ ++A PGGGRN + R R FS+ +PSE S+ +IF I G
Sbjct: 2200 WKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSD-- 2257
Query: 2754 GFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIK 2813
F V+ + + +V + ++ + +LPTPAK HYVFNLRDLS+ QG+L I+
Sbjct: 2258 -FPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIR 2316
Query: 2814 EPNDLLKLWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGEEKKLLVDCGIDTYFVD 2873
E + +L+ HEC+RV DR + D +F L + + FG + +D ++
Sbjct: 2317 EEIQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMANKHFG----IAID-------LE 2365
Query: 2874 FLRDAPEAAGETSEEADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFAD 2933
+ + P G+ + + +IY+ + L +L YN + + +VFF D
Sbjct: 2366 YFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLT-NPKEVKLVFFQD 2424
Query: 2934 AMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLME 2993
A+ H+ +I+R+IR +GNALLVGVGG+GKQSLTRLA+ I GY QI L+R YN + E
Sbjct: 2425 AIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHE 2484
Query: 2994 DLKVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLA 3053
DL+ LY+ AG + K + F+FTD +I E FLE +NN+L+SGEV NLF +DE++++ +
Sbjct: 2485 DLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLA-AT 2543
Query: 3054 SVMKKEFPRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTIDW 3113
KE + + YF+S+VRQ LHIVLC SPVGE FR+R FP+L++ CTIDW
Sbjct: 2544 RPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPSLVNCCTIDW 2603
Query: 3114 FSRWPKDALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHV 3173
F +WP++AL++VS+ F + D + E+K+++ + V+ Y+ RR +
Sbjct: 2604 FVQWPREALLSVSKTFFSQVDAG-NEELKEKLPLMCVNVHLSVSSMAERYYNELRRRYYT 2662
Query: 3174 TPKSYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQV 3233
TP SYL I Y + EK ++ + +R+ GL KL E + V + +L A E L
Sbjct: 2663 TPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLA 2722
Query: 3234 ANDKADMVLKEVTMKAQAAEKVKAEVQ------KVK-DRAQAIVDSISKDKAIAEEKLEA 3286
++ + +++++ + ++A++V+ VQ KVK + QAI D +D L+
Sbjct: 2723 KSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRD-------LDE 2775
Query: 3287 AKPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCT 3346
A PAL+ A AL ++ +DI+ +R +PP L+M +M+ + +L K
Sbjct: 2776 ALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAK------------- 2822
Query: 3347 MPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAGL 3406
P W + +L+ NFL+ L ++ K+ I +++ L Y PD+ E ++V +
Sbjct: 2823 -PDWPSAKQLLGDSNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSM 2881
Query: 3407 CSWTKAMASFFSINKEVLPLKANLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYE 3466
C W +AM + + K V P + L + + M L++ QA L + ++ +Q EY+
Sbjct: 2882 CMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYD 2941
Query: 3467 QAMTEKQTLLEDAERCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLATA 3526
+ + EK++L + + ++ A L + L E+ RW E Q+F + + G+V +A A
Sbjct: 2942 KGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAA 3001
Query: 3527 FLSYSGPFNQEFRDLLLNDWRKEMKARKIPFGKNLNLSEMLIDAPTISEWNLQGLPNDDL 3586
++Y G F ++R L+ W ++ ++ +IP + +L +L D I +WN GLP D +
Sbjct: 3002 CVAYYGAFTAQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDLI 3061
Query: 3587 SIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESRNELQITSLNHKYFRNHLEDSLSLGRP 3646
S +NGI+VT+ R+PL+IDPQ Q WI+NKES++ L+I L F LE+S+ LG P
Sbjct: 3062 STENGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLP 3121
Query: 3647 LLIEDVGEELDPALDNVLERNFIKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPE 3706
+L+E++ E LDPAL+ +L + +G +++GD ++D FR Y+TTK+PNP Y PE
Sbjct: 3122 VLLEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPE 3181
Query: 3707 ISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEKERTHLMEDVTANKRRMKELEDNLLY 3766
+ + +II+FTVT GLEDQLL V+ EK LE++R L+ + +K ++K +E+ +L
Sbjct: 3182 VCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILR 3241
Query: 3767 RLTSTQGSLVEDESLIVVLSNTKRTAEEVTQKLEISAETEVQINSAREEYRPVATRGSIL 3826
L +++G+++++E LI L ++K T+ + +LE + TE IN ARE+YRPVAT+GS++
Sbjct: 3242 MLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVM 3301
Query: 3827 YFLITEMRLVNEMYQTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVYKYAARG 3886
YF+I + ++ MYQ SL+ F LF+ ++ SVK+ +R+ ++E Y +RG
Sbjct: 3302 YFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRG 3361
Query: 3887 LYEEHKFLFTLLLTLKIDIQRNRVKHEEFLTLIKGGASLDLKACPPKP-SKWILDITWLN 3945
L+E+HK +++ +L +++ Q+ + E+ ++G A L+ K PPKP + W+ TW
Sbjct: 3362 LFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLE-KERPPKPEAPWLPTATWFA 3420
Query: 3946 LVELSK-LRQFSDVLDQISR--------------NEKMWKIWF-----DKENPEEEPL-- 3983
+L + F + I N + W+ + DK +E+
Sbjct: 3421 CCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAH 3480
Query: 3984 PNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLEKTWEESDPRT 4043
+ + L F +L+LI+ ++ + ++++++G+++ E +DL +++ T
Sbjct: 3481 QDPWSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNT 3540
Query: 4044 PLICLLSMGSDPTDSIIALGKRLKIETRY--VSMGQGQEVHARKLLQQTMANGGWALLQN 4101
PL+ +LS GSDP + + R +S+GQGQ A K+++ M +G W LQN
Sbjct: 3541 PLVFILSTGSDPMGAFQRFARESGYSERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQN 3600
Query: 4102 CHLGLDF---MDELMDIIIETE-LVHDAFRLWMTTEAHKQFPITLLQMSIKFANDPPQGL 4157
CHL + + M+EL+ + + + D FRL++++ FP+T+LQ S+K N+PP+GL
Sbjct: 3601 CHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGL 3660
Query: 4158 RAGLKRTYSGVSQDLLDVS-SGSQWKPMLYAVAFLHSTVQERRKFGALGWNIPYEFNQAD 4216
RA ++R ++ ++ + + G +W+ +++ + F H+ +QER+KFG LGWNI YEFN +D
Sbjct: 3661 RANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSD 3720
Query: 4217 FNATVQFIQNHLDDMDVKKG-VSWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSEN 4275
+ ++ + K+G + W + Y+ GEI YGGRVTD +D+R L T K +FS
Sbjct: 3721 RECALLNLK-----LYCKEGKIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPE 3775
Query: 4276 MFGPDFSFYQG--YNIPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVL 4333
D+ + + Y P ++ + YI++LP D PE+FG+H NA++ +Q K ++
Sbjct: 3776 TLEEDYKYSESGIYFAPMADSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLI 3835
Query: 4334 DTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDYVPFEVKERL---QKMGPFQPMN 4390
+TIL +QP+ ++GG ++ + +V L + ++P E L G +
Sbjct: 3836 NTILEVQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLT 3895
Query: 4391 IFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDARIPAWWKKASWI 4450
L QE+DR +L L+ ++L L AI G ++MSE + + + ++PA W ++
Sbjct: 3896 TVLGQEVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYP 3955
Query: 4451 S-STLGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALD 4509
S LG W +LI R S W+ G+P +W++GFF PQGFLT Q R +D
Sbjct: 3956 SLKPLGSWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTGTLQNHAR-KYNLPID 4014
Query: 4510 NMVLCNEVTKWMKD-------------------DISAP-PTEGVYVYGLYLEGAGWDKRN 4549
+ V +D D+ P P +GV V+G++++ + WD +
Sbjct: 4015 ELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKE 4074
Query: 4550 MKLIESKPKVLFELMPVIRIYAENNTLRDPRFYSCPIYKKPVRT--------DLNYIAAV 4601
M + ++ P + ++PV+ + N P Y CP+YK R N++ V
Sbjct: 4075 MVIEDALPGQMNPVLPVVHFEPQQNYKPSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTV 4134
Query: 4602 DLRTAQTPEHWVLRGVALLCDV 4623
L + ++ ++W+ +G ALLC +
Sbjct: 4135 LLPSKRSKDYWIAKGSALLCQL 4156
>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
Length = 4116
Score = 1868 bits (4838), Expect = 0.0
Identities = 1131/3317 (34%), Positives = 1794/3317 (54%), Gaps = 130/3317 (3%)
Query: 1389 EELFGLPATQYPQLLEIKKQLNLLQKIY-TLYNSVIETVNSYYDILWSEVNIEKINNELL 1447
EEL + YP L + K ++++ T Y I++ L+ +N E+I E+
Sbjct: 846 EELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFL-LNAEQIAEEIG 904
Query: 1448 EFQNRCRKLPRALKDWQA----FLDLKKIIDDFSECCPLLEYMASKAMMERHWERITTLT 1503
KL + L D A ++K ID F + P+L + M +RHW++I+ +
Sbjct: 905 NMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQISEIV 964
Query: 1504 GHSLDVGNESFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTFTFG 1563
G+ + E+ L N++E K+ E++E I +A KE +E+ L ++ +W N TF+F
Sbjct: 965 GYEIKP-TETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTFSFV 1023
Query: 1564 SFKTRGELLLRGDSTSEIIANMEDSLMLLG-------SLLSNRYNMPFKAQIQKWVQYLS 1616
++ D+ + I+ ++D MLL ++ + + P +A+ +KW + L
Sbjct: 1024 KYR---------DTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLI 1074
Query: 1617 NSTDIIESWMTVQNLWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVV 1676
D +++W+ Q W+YLE +F DI Q+P+E ++F +D W +M++A + ++
Sbjct: 1075 RIQDNLDAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRIL 1134
Query: 1677 QCCVGDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSH 1736
+ + L LE QK L YLEKKRL FPRFFF+S+ LLEIL + D
Sbjct: 1135 -VAADQPRMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPL 1193
Query: 1737 TIQAHLLNVFDNIKSVKFHEKIYDRILSISSQEGETIELDK---PVMAEGNVEVWLNSLL 1793
+Q HL F+ I ++F + + I+ + S E ET+ + P A+G VE WL +
Sbjct: 1194 RVQPHLKKCFEGIAKLEFTDNL--EIVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVE 1251
Query: 1794 EESQSSLHLVIR---QAAANIQETGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEAL-RNA 1849
+ +S+ VI +A + + L +P QV + + WT++ +AL N
Sbjct: 1252 QMMLASMREVIGLGIEAYVKVPRNHWVL-----QWPGQVVICVSSIFWTQEVSQALAENT 1306
Query: 1850 KFDKKIMQKTNQAFLELLNTLIDVTTRDLSSTERVKYETLITIHVHQRDIFDDLCHMHIK 1909
D ++K+N ++ + + LSS R+ L I VH RD+ L +
Sbjct: 1307 LLD--FLKKSNDQIAQI----VQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVS 1360
Query: 1910 SPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQA 1969
DF+W+ Q R+Y+ ++ I T+ + Y E+LG + RLVITPLTDRCY TL A
Sbjct: 1361 DLNDFQWISQLRYYWVAKDVQVQIITTEALYGY--EYLGNSPRLVITPLTDRCYRTLMGA 1418
Query: 1970 LGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWG 2029
L +++GGAP GPAGTGKTETTKD+ + L K VVFNCSD +D++ +G+ FKGLAQ+G+W
Sbjct: 1419 LKLNLGGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWA 1478
Query: 2030 CFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAG 2089
CFDEFNRI++ VLSV AQQI I K+FIF +G +++NP +F+TMNPGYAG
Sbjct: 1479 CFDEFNRIEVEVLSVVAQQILSIQQAIIRKLKTFIF-EGTELSLNPTCAVFITMNPGYAG 1537
Query: 2090 RQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQV 2149
R ELP+NLK FR+VAMMVPD +I + L S GF+D+ LA+K Y+LC EQLS Q
Sbjct: 1538 RAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQH 1597
Query: 2150 HYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLF 2209
HYD+G+R + SVL G K P + ES +++R L D+NL+K + +D PLF +I DLF
Sbjct: 1598 HYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLF 1657
Query: 2210 PNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKT 2269
P ++L K Y ++ +++ L P + K+IQ++E VRHG M +G GKT
Sbjct: 1658 PGVVLPKPDYEVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKT 1717
Query: 2270 TCIHTLMRAMTDCGKPHREMR-------MNPKAITAPQMFGRLDVATNDWTDGIFSTLWR 2322
+ L A+ D ++ +NPKAIT Q++G D +++W DG+ + +R
Sbjct: 1718 SAYKVLAAALGDLHAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFR 1777
Query: 2323 KTLRAKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNI 2382
+ + + WII DGPVDAIWIEN+N+VLDDNK L L +G+ I M +IFEP ++
Sbjct: 1778 EQASSLSDDRKWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADL 1837
Query: 2383 DNASPATVSRNGMVFMSSSILDWSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQ- 2441
+ ASPATVSR GM++M L W P+ + ++ + ++L + F L + C++
Sbjct: 1838 EQASPATVSRCGMIYMEPHQLGWKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEF 1897
Query: 2442 -NLEYKMEV------LEAFVITQSINMLQGLIPLKEQGGEVSQA--------HLGRLFVF 2486
L K V L ++ ++L + ++E+ E+ + L LF+F
Sbjct: 1898 GRLHCKFVVQTSPIHLAFSMMRLYSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLF 1957
Query: 2487 ALLWSAGAALELDGRRRLELWLRSRPTGTLELPPPAGP-----------GDTAFDYYVAP 2535
+L+W+ + D R++ +++ R+ G + P + +D+Y
Sbjct: 1958 SLVWTVAGTINADSRKKFDVFFRNLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIK 2017
Query: 2536 DGTWTHWNTRTQEYLYPSDTTP---EYGSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQ 2592
+ HW T TQ + P + +++P ++ R F ++T +L +G
Sbjct: 2018 QASG-HWETWTQYITKEEEKVPAGAKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPT 2076
Query: 2593 GTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKM 2652
GT K+ I F+ ++ +NFS+ T+ Q I S +D+R +GPP GKK
Sbjct: 2077 GTGKSAITNNFLLHLPKNTYLPNCINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKA 2136
Query: 2653 TVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGG 2712
VF+DD+NMP +G Q E++RQ ++ +G++ +K IVD+ + AM PGGG
Sbjct: 2137 VVFVDDLNMPAKEVYGAQPPIELLRQWID-HGYWFDKKDTTRLDIVDMLLVTAMGPPGGG 2195
Query: 2713 RNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRR 2772
RNDI R R +I + + + KIF I H+ +GF LV T+
Sbjct: 2196 RNDITGRFTRHLNIISINAFEDDILTKIFSSIVDWHF--GKGFDVMFLRYGKMLVQATKT 2253
Query: 2773 LWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIAD 2832
+++ LPTP+K HYVFNLRD SRV QG+L +++ ++LW HE RV D
Sbjct: 2254 IYRDAVENFLPTPSKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYD 2313
Query: 2833 RFTVSSDVTWFDKALVSLVEEEFGEE-KKLLVDCGIDTYFVDFLRDAPEAAGETSEEADA 2891
R D F + F + +K+L+ VD + E+D
Sbjct: 2314 RLIDKEDRQVFFNMVKETTSNCFKQTIEKVLIHLSPTGKIVDDNIRSLFFGDYFKPESDQ 2373
Query: 2892 ETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGN 2951
KIY+ I L + +L+ +N +I A M +V F A+ H+ +I RV++ +G+
Sbjct: 2374 ---KIYDEITDLKQLTVVMEHYLEEFN-NISKAPMSLVMFRFAIEHISRICRVLKQDKGH 2429
Query: 2952 ALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITF 3011
LLVG+GGSG+QS +L++F+ Y +QI +T++Y ++ EDLK + G K F
Sbjct: 2430 LLLVGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVF 2489
Query: 3012 IFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNENLH 3071
+F DN+IKDESF+E +N +L++G+V N+F DE +I + + + + + T +++
Sbjct: 2490 LFADNQIKDESFVEDINMLLNTGDVPNIFPADEKADIVEKMQTAARTQGEKVEVTPLSMY 2549
Query: 3072 DYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLT 3131
++F+ RV + L SP+G+ FRNR FP+LI+ CTIDWF WP DAL V+ FL
Sbjct: 2550 NFFIERVINKISFSLAMSPIGDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLE 2609
Query: 3132 SYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGE 3191
++D ++ + EVV FQ+ V + +DY+ + RR +VTP SYL I +K +
Sbjct: 2610 DVELDDNIRV--EVVSMCKYFQESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNS 2667
Query: 3192 KHVEVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQA 3251
K EV + NR TGL+KL A+ VA + +EL A + +L + +++ ++ ++ + +
Sbjct: 2668 KRQEVAMMRNRYLTGLQKLDFAASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETRE 2727
Query: 3252 AEKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRT 3311
A+ K VQ + A K E L A PALE A AAL T+ P+DI+ V++
Sbjct: 2728 ADGKKLLVQADEKEANVAAAIAQGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKS 2787
Query: 3312 LGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPS--WQESLKLMTAGNFLQNLQQF 3369
+ PP + +M+ + ++ K K D S M W S K++ FL++L+ +
Sbjct: 2788 MQNPPGPVKLVMESICIMKGMKPER-KPDPSGSGKMIEDYWGVSKKILGDLKFLESLKTY 2846
Query: 3370 PKDTINEEVIEFLSPYF-EMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKA 3428
KD I ++ + F P++ K V GLC W +AM + + K V P +
Sbjct: 2847 DKDNIPPLTMKRIRERFINHPEFQPAVIKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRE 2906
Query: 3429 NLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQT 3488
L E + MQ L + +AEL L + ++E+ T+K+ L E+ E C K+
Sbjct: 2907 RLREAEGKLAAQMQKLNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVR 2966
Query: 3489 ASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLNDWRK 3548
A LISGL GEK+RWTE +++ + L GDVLL++ ++Y G F ++R N W
Sbjct: 2967 AEKLISGLGGEKDRWTEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQWLA 3026
Query: 3549 EMKARKIPFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQT 3608
E K + IP + +LS L D I W + GLP D SI NGIIV+ + R+ L+IDP
Sbjct: 3027 ECKDKVIPGFSDFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSRRWALMIDPHG 3086
Query: 3609 QGKIWIKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNF 3668
Q WIKN E N+L + + + LE++L LG P+LIE++GEELD +++ +L +
Sbjct: 3087 QANKWIKNMEKANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKAT 3146
Query: 3669 IKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLL 3728
K +++G+ ++ F+LYITT+L NP Y PE++ + +++F +T GL+DQLL
Sbjct: 3147 FKQQGVEYMRLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLL 3206
Query: 3729 GRVILTEKQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNT 3788
G V EK ELE+++ L+ + NK+ +KE+ED +L L+ ++G+++EDE+ I VLS++
Sbjct: 3207 GIVAAKEKPELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSS 3266
Query: 3789 KRTAEEVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFL 3848
K +EE+++K ++++ TE QI+ R Y+PVA + ++F I+++ + MYQ SL F+
Sbjct: 3267 KVLSEEISEKQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFI 3326
Query: 3849 GLFDLSLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRN 3908
L+ SL S KS + RI II+H T +Y R L+E+ K LF+LLLT+ I Q+
Sbjct: 3327 NLYMHSLTHSTKSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKK 3386
Query: 3909 RVKHEEFLTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKM 3968
+ E + L+ GG +LD P P +W+ + W +V S L + +++ + +N
Sbjct: 3387 EITEEVWYFLLTGGIALDNPYPNPAP-QWLSEKAWAEIVRASALPKLHGLMEHLEQNLGE 3445
Query: 3969 WKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGV 4028
WK+ +D P EE LP ++ K +++++R PD+ + R++I + MG+ Y E
Sbjct: 3446 WKLIYDSAWPHEEQLPGSW-KFSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAP 3504
Query: 4029 ILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKI---ETRYVSMGQGQEVHARK 4085
DL+ ++ +S PLI +LS +DP ++ L + T+ +S+GQGQ A K
Sbjct: 3505 TFDLQGSYNDSSCCAPLIFVLSPSADPMAGLLKFADDLGMGGTRTQTISLGQGQGPIAAK 3564
Query: 4086 LLQQTMANGGWALLQNCHLGLDFM---DELMDIIIETELVHDAFRLWMTTEAHKQFPITL 4142
++ + +G W +LQNCHL +M +++ + +I E + FRLW+T+ ++FP+++
Sbjct: 3565 MINNAIKDGTWVVLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEKFPVSI 3624
Query: 4143 LQMSIKFANDPPQGLRAGLKRTY--SGVSQDLL--DVSSGSQWKPMLYAVAFLHSTVQER 4198
LQ IK N+PP+GLRA L R+Y +S + + W+ ML+ + F H+ VQER
Sbjct: 3625 LQNGIKMTNEPPKGLRANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQER 3684
Query: 4199 RKFGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDD 4258
R FG LGWNIPYEFN++D ++ IQ L+D K V + + Y+ GE YGGRVTDD
Sbjct: 3685 RNFGPLGWNIPYEFNESDLRISMWQIQMFLNDY---KEVPFDALTYLTGECNYGGRVTDD 3741
Query: 4259 YDKRLLNTFAKVWFSENMFGPDFSFYQG--YNIPKCSTVDNYLQYIQSLPAYDSPEVFGL 4316
D+RLL + +++ + + +S G Y IP + +Y+ Y+++LP PEVFGL
Sbjct: 3742 KDRRLLLSLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSYQSYIDYLRNLPITAHPEVFGL 3801
Query: 4317 HPNADITYQSKLAKDVLDTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDYVPFEV 4376
H NADIT ++ + + +L P+ + G G +E VV LA D+L KLP D+ EV
Sbjct: 3802 HENADITKDNQETNQLFEGVLLTLPRQSGGSGKSPQE-VVEELAQDILSKLPRDFDLEEV 3860
Query: 4377 KERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDCMF 4436
+L + + MN LRQE+ R R+ +VR +L L AI G ++MS L + + M
Sbjct: 3861 M-KLYPVVYEESMNTVLRQELIRFNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSML 3919
Query: 4437 DARIPAWWKKASWIS-STLGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQGFLTAM 4495
++PA W S+ S LG + +L+ R + F W+ G P FW++GF+ Q FLT +
Sbjct: 3920 VGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWIDKGPPVVFWISGFYFTQSFLTGV 3979
Query: 4496 RQEITRANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIES 4555
Q R +D++ EVT + + P +G Y+ GL+LEGA WD++ M++ ES
Sbjct: 3980 SQNYAR-KYTIPIDHIGFEFEVTP-QETVMENNPEDGAYIKGLFLEGARWDRKTMQIGES 4037
Query: 4556 KPKVLFELMPVIRIY-AENNTLRDPRFYSCPIYKKPVRT--------DLNYIAAVDLRTA 4606
PK+L++ +P+I + E+ Y CP+YK R NY+ +++L T
Sbjct: 4038 LPKILYDPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTD 4097
Query: 4607 QTPEHWVLRGVALLCDV 4623
+HW+ RGVA LC +
Sbjct: 4098 MPQKHWINRGVASLCQL 4114
>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
Length = 4523
Score = 1831 bits (4743), Expect = 0.0
Identities = 1179/3697 (31%), Positives = 1920/3697 (51%), Gaps = 162/3697 (4%)
Query: 989 HTINFRDSNSASNMKQNSLPIFRASVTLAIPNIVMAPALEDVQQTLNKAVECIISVPKGV 1048
H ++F N+ +K P F+A + L P IV P+L+ +
Sbjct: 925 HDLDFFLKNTEKQLKP--APFFQAQMILLPPEIVFKPSLD-----------------REA 965
Query: 1049 RQWSSELLSKKKIQERKMAALQSNEDSDSDVEMGENELQDTLEIASVNLPIPVQTKNYYK 1108
+L+ + +M+A + + +++ +N++ + L +A V I + N
Sbjct: 966 GDGFYDLVEEMLCNSFRMSAQMNRIATHLEIKNYQNDMDNMLGLAEVRQEIMNRVVNVIN 1025
Query: 1109 NVSENKEIVKLVSVLSTIINSTKKEVITSMDCFKRYNHIWQKGKEEAI--KTFITQSPLL 1166
V + + ++ + L + M F Y H + +A + Q P L
Sbjct: 1026 KVLDFRNTLETHTYLWV------DDRAEFMKHFLLYGHAVSSDEMDAHANEEIPEQPPTL 1079
Query: 1167 SEFESQILYFQNLEQEINAEPEYVCVGS-IALYTADLKFALTAETKAWMVVIGRHCNKKY 1225
+F+ QI ++ L +++ ++ S + K +L K W + H +
Sbjct: 1080 EQFKEQIDIYEALYVQMSKFEDFRVFDSWFKVDMKPFKVSLLTIIKKWSWMFQEHLLRFV 1139
Query: 1226 RSEMENIFMLIEEFNKKLNRPIK--DLDDIRIAMAALKEIREEQISIDFQVGPIEESYAL 1283
+ + I+E + L R + D D + M L +R Q + D P++E+ L
Sbjct: 1140 IDSLNELQEFIKETDSGLQRELNEGDHDGLVDIMVHLLAVRSRQRATDELFEPLKETITL 1199
Query: 1284 LNRYGLLIAREEIDKVDTLHYAWEKLLARAGEVQNKLVSLQPS----FKKE--LISAVEV 1337
L YG + + +++ L WE A V++++ L + +K+ L A +
Sbjct: 1200 LESYGQKMPEQVYIQLEELPERWETTKKIAATVRHEVSPLHNAEVTLIRKKCILFDAKQA 1259
Query: 1338 FLQDCHQFYLDYDLNGPMASGLKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPAT 1397
++ + Y N P A D+ + + + + + LF +
Sbjct: 1260 EFRERFRHYAPLGFNAE-----NPYTALDKA---NEELEALEEEMLQMQESTRLFEVALP 1311
Query: 1398 QYPQLLEIKKQLNLLQKIYTLYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCR--- 1454
+Y Q+ + +K++ LL+ ++ + V +++++ W ++++E+++ EL F
Sbjct: 1312 EYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVELRRFAKASSITE 1371
Query: 1455 --KLPRALKDWQAFLDLKKIIDDFSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNE 1512
L + ++ W A+ L+ + D + + + S A+ +RHW ++ G + NE
Sbjct: 1372 IWSLNKEVRVWDAYTGLEGTVKDMTASLRAITELQSPALRDRHWHQLMKAIGVKFLI-NE 1430
Query: 1513 SFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELL 1572
+ L +++ L + ++++ I AVKE E+ + ++ W F++ G L
Sbjct: 1431 ATTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVITEISQTWATMKFSYEVHYRTGIPL 1490
Query: 1573 LRGDSTSEIIANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLW 1632
L+ D ++ +E + + L +LL ++Y F Q+ W L+ + +I +WM VQ W
Sbjct: 1491 LKSDE--QLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTWMEVQRTW 1548
Query: 1633 IYLEAVFV-GGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPH 1691
+LE++FV DI QL K+A+RF +D + ++M + +V +V++ L + L
Sbjct: 1549 SHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTAKVENVLEATCRPN-LYEKLKD 1607
Query: 1692 LLDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKS 1751
L +L +C+K+L YLE KR+ FPRF+FVS LL+IL + + + HL +FD+I
Sbjct: 1608 LQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLDILSKGAQPKQVTCHLAKLFDSIAD 1667
Query: 1752 VKFHEK---IYDRILSISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAA 1808
++F + R + + S+E E + G+VE WL L + Q ++ I +A
Sbjct: 1668 LQFEDNQDVSAHRAVGMYSKEKEYVPFQAECECVGHVETWLLQLEQTMQETVRHSITEAI 1727
Query: 1809 ANIQETGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEAL-RNAKFDKKIMQKTNQAFLELL 1867
+E +L F FPAQV L Q+ WT D A R + + ++ ++ + L
Sbjct: 1728 VAYEEKPRELWIF--DFPAQVALTSSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQL 1785
Query: 1868 NTLIDVTTRDLSSTERVKYETLITIHVHQRDIFDDLCHMH--IKSPMDFEWLKQCRFYFN 1925
NTLI + +L +R K T+ TI VH RD+ L + SP F WL Q R +
Sbjct: 1786 NTLITLLLGELPPGDRQKIMTICTIDVHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWE 1845
Query: 1926 EDSDKMMIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTG 1985
+ ++I D F Y E+LG + RLVITPLTDRCYITL Q+L ++M GAPAGPAGTG
Sbjct: 1846 DTQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTG 1905
Query: 1986 KTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVA 2045
KTETTKD+GR LG V VFNCS+QMD++ +G I+KGL Q+G+WGCFDEFNRI + VLSV
Sbjct: 1906 KTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVV 1965
Query: 2046 AQQISIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVA 2105
A Q+ +I + KK F+F G+ +T+ P G+F+TMNPGYAGR ELPENLK FR A
Sbjct: 1966 AVQVKMIHDAIRNRKKRFVFL-GEAITLKPSVGIFITMNPGYAGRTELPENLKALFRPCA 2024
Query: 2106 MMVPDRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTL 2165
M+ PD ++I + L + GF+D LARKF TLY LC+E LSKQ HYD+GLR I SVL
Sbjct: 2025 MVAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVA 2084
Query: 2166 GAAKRANPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAA 2225
G+ KR + E ++MR LRD N+ K++ +D P+FL L+ DLFP + + + E
Sbjct: 2085 GSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHFEQM 2144
Query: 2226 ISRQVEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKP 2285
+ + E L + LKV+QL E VRH + +G +G GK+ + TL R + +
Sbjct: 2145 VRQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNMKQK 2204
Query: 2286 HREMRMNPKAITAPQMFGRLDVATNDWTD---------GIFSTLWRKTLRAKKGEHIWII 2336
+NPKA+T ++FG + AT +W D G+FS++ R+ K WI+
Sbjct: 2205 PVWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIV 2264
Query: 2337 LDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMV 2396
LDG +D +WIE+LN+V+DDNK LTLA+ +RI + P +++FE H++ +A+PATVSR G++
Sbjct: 2265 LDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGIL 2324
Query: 2397 FMSSSILDWSPILEGFLKKRSPQEAE----ILRQLYTESFPDLYRFCIQNLEYKMEVLEA 2452
+++ L W+P + ++ +R Q + IL Y + D R + + + E+
Sbjct: 2325 YVNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYVPACLDKLRTSFKTI---TSIPES 2381
Query: 2453 FVITQSINMLQGLIPLKEQGGEVSQAHLGRLFVFALLWSAGAALELDG----RRRLELWL 2508
++ +L+ L+ + + + FVFA +W+ G L D + W
Sbjct: 2382 SLVQTLCVLLECLLTPENVPSDSPKEVYEVYFVFACIWAFGGTLLQDQISDYQADFSRWW 2441
Query: 2509 RSRPTGTLELPPPAGPGDTAFDYYV-APDGTWTHWNTRTQEYLYPSDTTPEYGSILVPNV 2567
+ + ++ P T FDYYV W + ++ D + ++LV
Sbjct: 2442 Q-KEMKAVKFPSQG----TIFDYYVDHKTKKLLPWADKIAQFTMDPDVPLQ--TVLVHTT 2494
Query: 2568 DNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPLM 2627
+ R + ++ + ++GK ++L+G G KTV + ++ E +++ + F+ TT
Sbjct: 2495 ETARLRYFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASLS-EDYIVSRVPFNYYTTSTA 2553
Query: 2628 FQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYN 2687
Q+ +E ++K+ G YGP KK+ FIDD+NMP ++ +G + ++RQ ++ +Y+
Sbjct: 2554 LQKILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYD 2613
Query: 2688 LEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVG 2747
+K I + Q++A M +P G I RL+R F++F PS +++ I+G I
Sbjct: 2614 RQKV-MLKEIHNCQYVACM-NPMVGSFTINPRLQRHFTVFAFNFPSLDALNTIYGQIFSF 2671
Query: 2748 HYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNT 2807
H+ Q+ F+ + S L+ T Q LPT KFHY+FNLRDLS V+QG+L
Sbjct: 2672 HF-QQQAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFA 2730
Query: 2808 TSEVIKEPNDLLKLWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGEEKKLLVDCGI 2867
+ E +K P DL+ LW HE RV D+ D F + ++ + F GI
Sbjct: 2731 SPECLKGPLDLIHLWLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFE---------GI 2781
Query: 2868 DTYFVDFLRDAPEAAGETSEEADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMD 2927
D++ L P AD Y P++ + LK L L YNE A M
Sbjct: 2782 DSH---MLLQQPLI---YCHFADRGKDPHYMPVKDWEVLKTILTETLDNYNE--LNAAMH 2833
Query: 2928 MVFFADAMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYN 2987
+V F DAM H+ +ISR++RTPQG ALLVGVGGSGKQSL+RLA+++ G FQITLT Y
Sbjct: 2834 LVLFEDAMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYG 2893
Query: 2988 TSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDE 3047
L DL LY G + F+ TD ++ DESFL +N++L+SGE+ +LF+ +++D+
Sbjct: 2894 IQELRVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDK 2953
Query: 3048 INSDLASVMKKEFPRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALIS 3107
I S + + + + + EN +FM+RVR L I+LCFSPVG R RA KFPA+++
Sbjct: 2954 IISGIHN--EVHALGMVDSRENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVN 3011
Query: 3108 GCTIDWFSRWPKDALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRF 3167
IDWF WP++ALV+VS F+ K + M V E Y+Q
Sbjct: 3012 CTAIDWFHAWPQEALVSVSRRFIEETK-GIEPVHKDSISLFMAHVHTTVNEMSTRYYQNE 3070
Query: 3168 RRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELEAK 3227
RR + TPKS+L I +K + +K EV R+ G++KLK + V L L ++
Sbjct: 3071 RRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQ 3130
Query: 3228 EKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAA 3287
E ELQ+ N A+ ++ ++ ++ + + K + + AI + + + E L A
Sbjct: 3131 EAELQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKA 3190
Query: 3288 KPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTM 3347
+PAL A AAL T+ +++ ++ PP + + V++L + K
Sbjct: 3191 EPALVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVPK--------D 3242
Query: 3348 PSWQESLKLM-TAGNFLQNLQQFPKDTINEEVIEFLSP-YFEMPDYNIETAKRVCGNVAG 3405
SW+ + M +FLQ L + K+ I E ++ ++ Y + P++N + AG
Sbjct: 3243 RSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAAAG 3302
Query: 3406 LCSWTKAMASFFSINKEVLPLKANLVVQENRHL-LAMQDLQKAQAELDDKQAELDVVQAE 3464
LC+W + F+ + +V P K + Q N L A + L+ + +L D L + A
Sbjct: 3303 LCAWVINIIKFYEVYCDVEP-KRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTAS 3361
Query: 3465 YEQAMTEKQTLLEDAERCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLA 3524
+E+A EK E+ + ++ A+ L+ L +K RW + + F AQ K L GDVLL
Sbjct: 3362 FEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLT 3421
Query: 3525 TAFLSYSGPFNQEFRDLLLN-DWRKEMKAR-KIPFGKNLNLSEMLIDAPTISEWNLQGLP 3582
AF+SY GPF +++R L++ W ++ + IP + L+L ML D TI+ WN +GLP
Sbjct: 3422 AAFVSYVGPFTRQYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLP 3481
Query: 3583 NDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESRNELQITSLNHKYFRNHLEDSLS 3642
+D +S +N I+T R+PL+IDPQ QG WIKNK +L++T L K F N +E +L+
Sbjct: 3482 SDRMSTENAAILTHCERWPLVIDPQQQGIKWIKNKYGM-DLKVTHLGQKGFLNAIETALA 3540
Query: 3643 LGRPLLIEDVGEELDPALDNVLERNFIKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPA 3702
G +LIE++ E +DP LD +L RN IK G +++GDKE + FRL + TKL NP
Sbjct: 3541 FGDVILIENLEETIDPVLDPLLGRNTIKKGK--YIRIGDKECEFNKNFRLILHTKLANPH 3598
Query: 3703 YTPEISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEKERTHLMEDVTANKRRMKELED 3762
Y PE+ A+T++++FTVT GLE QLL V+ E+ +LEK + L + K +K LED
Sbjct: 3599 YKPELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLED 3658
Query: 3763 NLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEVTQKLEISAETEVQINSAREEYRPVATR 3822
+LL RL++ +GS ++D L+ L TK T E+ K+ + E E +IN ARE YRPVA R
Sbjct: 3659 DLLLRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAAR 3718
Query: 3823 GSILYFLITEMRLVNEMYQTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVYKY 3882
S+LYF+I +++ +N +YQ SL+ F LF ++ ++ K RI+ ++E +T+ V+ Y
Sbjct: 3719 ASLLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLY 3778
Query: 3883 AARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEFLTLIKGGASLDLKACPPKPSKWILDIT 3942
++ L+E+ K F + +I +++ + E L++ ++ P ++ +
Sbjct: 3779 TSQALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLLR----FTVEHTHLSPVDFLTSQS 3834
Query: 3943 WLNLVELSKLRQFSDVLDQISRNEKMWKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRS 4002
W + ++ + +F + + + K W+ W + E PE+E LP + K ++L+L+R+
Sbjct: 3835 WSAIKAIAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKK-SLIQKLILLRA 3893
Query: 4003 WCPDRTIAQARKYIVDSMGEKYAEGVILDLEKTWEESDPRTPLICLLSMGSDPTDSIIAL 4062
PDR R ++ + +G KY E LDL K +EES P TP+ +LS G D + L
Sbjct: 3894 MRPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEIL 3953
Query: 4063 GKRLKI-----ETRYVSMGQGQEVHARKLLQQTMANGGWALLQNCHLGLDFMDELMDIII 4117
GKRL + VS+GQGQE A L++ G W +LQN HL ++ L ++
Sbjct: 3954 GKRLGFTIDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLE 4013
Query: 4118 E-TELVHDAFRLWMTTEA-----HKQFPITLLQMSIKFANDPPQGLRAGLKRTYSGVSQD 4171
++ H +R++M+ E+ P LL+ SIK N+PP G+ A L QD
Sbjct: 4014 RFSQGSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQD 4073
Query: 4172 LLDVSSGSQ-WKPMLYAVAFLHSTVQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDD 4230
L++ S Q +K +L+++ + H+ V R +FG GW+ Y FN D + N+L
Sbjct: 4074 TLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYL-- 4131
Query: 4231 MDVKKGVSWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFGPDFSFYQGYNIP 4290
+ V W +RY+ GEI YGG +TDD+D++L + + + + ++ + G+ P
Sbjct: 4132 -EANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTEDELMLAPGFAAP 4190
Query: 4291 KCSTVDNYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVLDTILGIQPKDTSGGGD- 4349
Y QYI+ + +SP ++GLHPNA+I + + + + T+L +QP++ G +
Sbjct: 4191 PYLDYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDEL 4250
Query: 4350 -ETREAVVARLADDMLEKLPPDYVPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVR 4408
++ E V + DD+LEKLP + F + E +QK P + QE +RM ++ +R
Sbjct: 4251 GQSTEEKVKNVLDDILEKLPEE---FNMAEIMQKNSNRSPYVLVCFQECERMNILIREIR 4307
Query: 4409 STLTELKLAIDGTIIMSENLRDALDCMFDARIPAWWKKASWISS-TLGFWFTELIERNSQ 4467
+L +L L++ G + +S + + +P W K ++ S+ L WF +L+ R +
Sbjct: 4308 ISLEQLDLSLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRE 4367
Query: 4468 FTSWVFN-GRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKWMKDDIS 4526
+W + P W++GFFNPQ FLTA+ Q + R N+ W LD L +VTK K+D
Sbjct: 4368 LDTWTQDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNE-WPLDKTRLTADVTKKTKEDYG 4426
Query: 4527 APPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIYAENNTLRDPR-FYSCP 4585
PP EG Y++GL++EGA WD + ++E++ K L MPVI A ++ + Y CP
Sbjct: 4427 HPPREGAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECP 4486
Query: 4586 IYKKPVRTDLNYIAAVDLRTAQTPEHWVLRGVALLCD 4622
+Y+ +R +YI L++ + WVL GVALL +
Sbjct: 4487 VYRTKLRGP-SYIWTFRLKSEEKTAKWVLAGVALLLE 4522
Score = 167 bits (424), Expect = 2e-40
Identities = 168/753 (22%), Positives = 311/753 (41%), Gaps = 68/753 (9%)
Query: 130 FIRTDPSKAITPDNIHQEVSFNMLDAADGGLLNSVRRLLSDIFIPAL-RATSHGWGELEG 188
FI +++I ++ Q V F L A L V L +I +P L +H
Sbjct: 128 FISKKITESIGVNDFSQVVLFGELPALS---LGHVSAFLDEILVPVLSNKNNHKSWSCFT 184
Query: 189 LQDAANIRQEFLSSLEGFVNVLSGAQESLKEKVNLRKCDILELKTLKEPTDYLTLANNPE 248
QD +E + V+ + K++ R + K D N P
Sbjct: 185 SQD-----------MEYHIEVMKKKMYIFRGKMSRRTLLPIPTVAGKMDLDQNCSENKPP 233
Query: 249 T-----LGKIEDCMKVWIKQTEQVLAENN-QLLKEADDVGPRAELEHWKKRLSKFNYLLE 302
+ L IE + W Q ++++ ++ Q L + P+AEL+ W R + + +
Sbjct: 234 SNERIILHAIESVVIEWSHQIQEIIERDSVQRLLNGLHLSPQAELDFWMMRRENLSCIYD 293
Query: 303 QLKSPDVKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLEKCCDPLYSSD 362
QL++P V ++ +L +S T +++ + + +A EA+D YL L + L ++
Sbjct: 294 QLQAPVVLKMVKILTTKQSSYFPTLKDIFLAVENALLEAQDVELYLRPLRRHIQCLQETE 353
Query: 363 PLSMMDAIPTLINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAYITNNGTASIWN 422
I L + I +I+S S +YNT ++ L + N I+ AY++
Sbjct: 354 FPQTRILIAPLFHTICLIWSHSKFYNTPARVIVLLQEFCNLFINQATAYLS--------- 404
Query: 423 QPQDVVE-------EKILSAIKLKQEYQLCFHKTKQKLK---QNPNAKQFDFSEMYIFGK 472
P+D++ EK+ A+ + + ++ F ++KL + +DF +F +
Sbjct: 405 -PEDLLRGEIEESLEKVQVAVNILKTFKNSFFNYRKKLASYFMGRKLRPWDFQSHLVFCR 463
Query: 473 FETFHRRLAKIIDIFTTLKTYSVLQDSTIEG---------LEDMATKYQGIVATIKKKEY 523
F+ F RL KI DIF T + L+ G + +M+ + + K+ Y
Sbjct: 464 FDKFLDRLIKIEDIFATTLEFEKLERLEFGGTKGAILNGQVHEMSEELMELCKLFKQSTY 523
Query: 524 NFLDQRKMDFDQDYEEFCKQTNDLHNELRKFMDVTFAKIQNTNQALRMLKKF----ERLN 579
+ D M+F+ DY F +T + L + F A ++L F E+
Sbjct: 524 DPSDCTNMEFESDYVAFKSKTLEFDRRLGTIICEAFFNCNGLEAAFKLLTIFGNFLEKPV 583
Query: 580 IPNLGIDDKYQLILENYGADIDMISKLYTKQKYD-----PPLARNQPPIAGKILWARQLF 634
+ + Y ++ + ++D+ +LY + L +N P +G + WA+Q+
Sbjct: 584 VMEI-FSLHYSTLVHMFNTELDVCKQLYNEHMKQIECGHVVLNKNMPFTSGNMKWAQQVL 642
Query: 635 HRIQQPMQLFQQ-HPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWLRQIEEI-HVGL 692
R+Q F L + + + Y M +L +FE + W ++EI L
Sbjct: 643 QRLQMFWSNFASLRYLFLGNPDHALVYQKYVEMTTLLDQFESRIYNEWKSNVDEICEFNL 702
Query: 693 EASLLVKAPGTGELFVNFDPQILILFRETECMAQMGLEVSP-LATSLFQKRDRYKRNFSN 751
L+ + G L VNFDP+++ + RE + + + + P A ++F+KR+ + N
Sbjct: 703 NQPLVKFSAINGLLCVNFDPKLVAVLREVKYLLMLKKQDIPDSALAIFKKRNTILKYIGN 762
Query: 752 MKMMLAEYQRVKSKIPAAIEQLIVPHLAKVDEALQPGLAALTWTSLNIEAYLENTFAKIK 811
+ +++ Y ++K + LI L +DE L LTW + Y+E A
Sbjct: 763 LDLLVQGYNKLKQTLLEVEYPLIEDELRAIDEQLTAATTWLTWQD-DCWGYIERVRAATS 821
Query: 812 DLELLLDRVNDLIEFRIDAILEEMSSTPLCQLP 844
+LE ++R + + I + M C LP
Sbjct: 822 ELEHRVERT----QKNVKVIQQTMRGWARCVLP 850
>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
Length = 4646
Score = 1355 bits (3508), Expect = 0.0
Identities = 964/3524 (27%), Positives = 1693/3524 (48%), Gaps = 288/3524 (8%)
Query: 1296 IDKVDTLHYAWEKLLARAGE-VQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGP 1354
ID ++ A+ ++ R +Q ++ +LQ +E AVE D D++ P
Sbjct: 1211 IDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQE-DRAVESRTTD---LLTDWEKTKP 1266
Query: 1355 MASGLKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNL--- 1411
+ L+P+EA L +++ +F + +E L T E + Q+ L
Sbjct: 1267 VTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEEL 1326
Query: 1412 --LQKIYTLYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDL 1469
L+ +++ + V E ++ + W V K+ L N+ + P L+ + ++ +
Sbjct: 1327 QDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEFV 1386
Query: 1470 KKIIDDFSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKE 1529
++++ + + L+ + S+A+ +RHW+++ + V L I + L K +
Sbjct: 1387 QRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSE--LTLGQIWDVDLQKNEA 1444
Query: 1530 EIEDICISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEIIANMEDSL 1589
++D+ + A E +E+ LKQ+ W+ +++ + L+ D ++ +++ +
Sbjct: 1445 IVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWD---DLFNKVKEHI 1501
Query: 1590 MLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGG-DIAKQL 1648
+ ++ + Y F+ W L+ + + W+ VQ W+YLE +F G DI L
Sbjct: 1502 NSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLL 1561
Query: 1649 PKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLE 1708
P E +RF +I ++ +M + + P V+ + + + + L L D L QK+L YLE
Sbjct: 1562 PVETQRFQSISTEFLALMKKVSKSPLVMDV-LNIQGVQRSLERLADLLGKIQKALGEYLE 1620
Query: 1709 KKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDRILSISSQ 1768
++R FPRF+FV D LLEI+G + + +Q H +F + S+ +E +L ISS+
Sbjct: 1621 RERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNED-NSVVLGISSR 1679
Query: 1769 EGETIELDKPVMAEGNVEV--WLNSLLEESQSSLHLVIRQAAANIQETGFQLT------- 1819
EGE + PV + ++ WL + +E + +L ++ ++ ++ G +
Sbjct: 1680 EGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYI 1739
Query: 1820 EFLSSFPAQVGLLGIQMIWTRDSEEALRN--AKFDKKIMQKTNQAFLELLNTLIDVTTRD 1877
++ + AQ+ +L Q+ W+ + E AL + D + LN L D +
Sbjct: 1740 TWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLME 1799
Query: 1878 LSSTERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDS----DKMMI 1933
R K E LIT VHQRD+ L I + FEWL Q RFYF+ ++ I
Sbjct: 1800 QPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSI 1859
Query: 1934 HITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDM 1993
+ + F Y E+LG D+LV TPLTDRCY+T+ QAL +GG+P GPAGTGKTE+ K +
Sbjct: 1860 QMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKAL 1919
Query: 1994 GRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIIL 2053
G LG++V+VFNC + DF+ +GRIF GL Q G+WGCFDEFNR++ +LS +QQ+ I
Sbjct: 1920 GHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQ 1979
Query: 2054 TCKKEH------KKSFIFTD---GDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSV 2104
+EH K S T V ++P+ +F+TMNPGYAGR LP+NLK FRS+
Sbjct: 1980 EALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSL 2039
Query: 2105 AMMVPDRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRT 2164
AM PDRQ+I +V L S GF VLA K +KLC+EQLS Q HYDFGLR + SVL +
Sbjct: 2040 AMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVS 2099
Query: 2165 LGAAKR----------------------ANPMDTESTIVMRVLRDMNLSKLIDEDEPLFL 2202
G KR A + + ++ V M + KL+ ED PL
Sbjct: 2100 AGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETM-VPKLVAEDIPLLF 2158
Query: 2203 SLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPP------WKLKVIQLFETQRVRH 2256
SL+ D+FP + + L + + +E L W KV+QL++ ++ H
Sbjct: 2159 SLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINH 2218
Query: 2257 GMMTLGPSGAGKTTCIHTLMRAMTDC-GKPHREMRMNPKAITAPQMFGRLDVATNDWTDG 2315
G+M +GPSG+GK+ L++A+ G ++PKAI+ ++G LD T +WTDG
Sbjct: 2219 GLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDG 2278
Query: 2316 IFSTLWRKTLRAKKGE---HIWIILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPN 2372
+F+ + RK + + +GE WI+ DG VD W+ENLNSVLDDNK LTL NG+R+ + PN
Sbjct: 2279 LFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPN 2338
Query: 2373 CKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFL----------------KKR 2416
+I+FE ++ A+ ATVSR GMV+ S +L I FL ++R
Sbjct: 2339 VRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRR 2398
Query: 2417 SPQE------AEILRQLYTESFPDLYRFCIQN------LEYKMEVLEAFVITQSINMLQG 2464
+E A + Q+ ++ + + N LE+ ++ +T+ + L
Sbjct: 2399 KGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTR-LRCLGS 2457
Query: 2465 LIPLKEQGG-----------------EVSQAHLGRLFVFALLWSAGAALELDGRRRLELW 2507
L + Q E + ++ R V+A+LWS L R L +
Sbjct: 2458 LFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEY 2517
Query: 2508 LRSRPTGTLELPPPAGPGDTAFDYYVAPDGTWTHWNTRTQEYLYPSDTTPEYGSILVPNV 2567
+R T +P P P DY V+ G W+ W + + + ++VP +
Sbjct: 2518 IRRITT----VPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAA-PDVVVPTL 2572
Query: 2568 DNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPLM 2627
D VR + L+ T + K ++L G G+ KT+ + + P+ ++ LNFSSATTP +
Sbjct: 2573 DTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRAL-PDMEVV-GLNFSSATTPEL 2630
Query: 2628 FQRTIESYVDKRM---GTTYGP-PAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQN 2683
+T + Y + R G P GK + +F D++N+P ++++G Q +RQ++E
Sbjct: 2631 LLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHG 2690
Query: 2684 GFYNLEKPGEFTSIVDIQFLAAMIHPGG-GRNDIPQRLKRQFSIFNCTLPSEASVDKIFG 2742
GFY + + IQF+ A P GR + R R + P AS+ +I+G
Sbjct: 2691 GFYRTSDQ-TWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYG 2749
Query: 2743 VIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKM--LPTPAKFHYVFNLRDLSRV 2800
R + T PLT + + + + HY+++ R+++R
Sbjct: 2750 TFN-------RAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRW 2802
Query: 2801 WQGMLNTTSEVIKEPND-LLKLWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGEEK 2859
+G+ + P + L+++W HE R+ DR + W D+ + ++ + F
Sbjct: 2803 VRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNID 2862
Query: 2860 KLLVDCGIDTYFVDFLRDAPEAAGETSEEADAETPKIYEPI---ESFSHLKERLNMFLQL 2916
+ E A K Y P+ E ++K RL +F
Sbjct: 2863 R-------------------EKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVF--- 2900
Query: 2917 YNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYV 2976
Y E + + +V F + + H+++I R+ R PQG+ LL+GV G+GK +L+R +++ G
Sbjct: 2901 YEEEL---DVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLS 2957
Query: 2977 SFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEV 3036
+QI + R Y + EDL+ + R +G + + I FI ++ + D FLE MN +L++GEV
Sbjct: 2958 VYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEV 3017
Query: 3037 SNLFARDEIDEINSDLASVMKKEFPRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFR 3096
LF DE + + +KE L ++E L+ +F S+V +NLH+V +P E +
Sbjct: 3018 PGLFEGDEYATLMTQCKEGAQKE-GLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLK 3076
Query: 3097 NRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSYDIDCSLEIKKEVVQCM------- 3149
+RA PAL + C ++WF W +AL V + F + D++ I + + +
Sbjct: 3077 DRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQP 3136
Query: 3150 GSFQDGVAEKCVDYFQ-----------RFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRT 3198
S ++ + CV Q R R+ +TP+ YL FI Y ++ EK E+
Sbjct: 3137 PSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEE 3196
Query: 3199 LANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAE 3258
+N GL K+KE + V L ++L K +EL+V N A+ LK++ Q AEK K
Sbjct: 3197 QQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVM 3256
Query: 3259 VQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHL 3318
Q+++++ + I+ + +E L+ +PA+ EA+ A+++I+ + VR++ PP
Sbjct: 3257 SQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAA 3316
Query: 3319 IMRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEV 3378
+ ++ + LL L +S T W++ ++ NF+ + F + I++ +
Sbjct: 3317 VKLALESICLL-----------LGESTT--DWKQIRSIIMRENFIPTIVNFSAEEISDAI 3363
Query: 3379 IEFLSP-YFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQENRH 3437
E + Y P YN E R + W A ++ + K V PL+ L E+
Sbjct: 3364 REKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDA 3423
Query: 3438 LLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLA 3497
Q + + + D +A + + EY ++E Q + D K+ ++ L+ L+
Sbjct: 3424 KDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLS 3483
Query: 3498 GEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLNDWRKEMKARKIPF 3557
E+ERW + S+ F Q + GD LL+ AF++Y+G F+Q+ R L W ++ I F
Sbjct: 3484 AERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQF 3543
Query: 3558 GKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNK 3617
++ +E L +A W LP DDL +N I++ + +RYPL+IDP Q +I N+
Sbjct: 3544 RTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNE 3603
Query: 3618 ESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTGSTFKV 3677
++ TS FR +LE +L G PLL++DV E DP L+ VL R +TG +
Sbjct: 3604 YKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDV-ESYDPVLNPVLNREVRRTGGRVLI 3662
Query: 3678 KVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTEKQ 3737
+GD+++D+ F ++++T+ P + P++ +R + ++FTVT L+ Q L V+ E+
Sbjct: 3663 TLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERP 3722
Query: 3738 ELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEVTQ 3797
+++++R+ L++ + R+++LE +LL L +G +++D+++I L N KR A EVT+
Sbjct: 3723 DVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTR 3782
Query: 3798 KLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSLAR 3857
K+E + ++ + ++Y P++T S +YF + ++ ++ +YQ SL+ FL ++ L
Sbjct: 3783 KVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYE 3842
Query: 3858 SVK-SPIT--SKRIANIIEHMTYEVYKYAARG-LYEEHKFLFTLLLTLKIDIQRNRVKHE 3913
+ +T ++R++ I + + + ARG L+++H LL +K+ ++
Sbjct: 3843 NPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYD 3902
Query: 3914 -EFLTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIW 3972
EF ++G + P+ ++ +V LS L F D++ ++ +E+ + IW
Sbjct: 3903 AEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEA-VVRLSCLPAFKDLIAKVQADEQ-FGIW 3960
Query: 3973 FDKENPEEEPLPNAYDKSL------DCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAE 4026
D +P E+ +P + + RLLLI+++ PDR +A A ++ ++GE +
Sbjct: 3961 LDSSSP-EQTVPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMS 4019
Query: 4027 GVILDLEKT---WEESDPRTPLICLLSMGSDPTDSIIALGKRLKIETRYVSMGQGQEVH- 4082
+ L+ T E P TP++ G D + + L + +++G + +
Sbjct: 4020 IMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQ 4079
Query: 4083 ARKLLQQTMANGGWALLQNCHLGLDFMDELMDIIIETELVHDAFRLWMTTEAHKQFPITL 4142
A K + + +G W +L+N HL ++ +L + + + H FRL++T E + + P+ L
Sbjct: 4080 ADKAINTAVKSGRWVMLKNVHLAPGWLMQL-EKKLHSLQPHACFRLFLTMEINPKVPVNL 4138
Query: 4143 LQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSGSQWKPMLYAVAFLHSTVQERRKFG 4202
L+ F +PP G++A + RT+S + + S ++ + + +A+ H+ +QER ++
Sbjct: 4139 LRAGRIFVFEPPPGVKANMLRTFSSIPVSRI-CKSPNERARLYFLLAWFHAIIQERLRYA 4197
Query: 4203 ALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKG--------VSWTTIRYMIGEIQYGGR 4254
LGW+ YEF ++D + + LD D KG + W+ ++ ++ + YGGR
Sbjct: 4198 PLGWSKKYEFGESDLRSACDTVDTWLD--DTAKGRQNISPDKIPWSALKTLMAQSIYGGR 4255
Query: 4255 VTDDYDKRLLNTFAKVWFSENMFGPDFSF------YQGYNIPKCSTVDNYLQYIQSLPAY 4308
V +++D+RLLNTF + F+ F +F ++ +P + ++Q+++ LP
Sbjct: 4256 VDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDT 4315
Query: 4309 DSPEVFGLHPNADITYQSKLAKDVLDTILGIQ-----------------PKDTSGGGDET 4351
+P GL NA+ + D++ +L +Q D++ G
Sbjct: 4316 QTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPA 4375
Query: 4352 REAVVARLADDMLEKLPPDYVPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTL 4411
+ A + L +P +K ++ + P+ F +E+ ++L VR L
Sbjct: 4376 WMRTLHTTASNWLHLIPQTL--SHLKRTVENIK--DPLFRFFEREVKMGAKLLQDVRQDL 4431
Query: 4412 TELKLAIDGTIIMSENLRDALDCMFDARIPAWWKK---------ASWISSTLGFWFTELI 4462
++ +G + LR ++ + +P W W+S F+E I
Sbjct: 4432 ADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSD-----FSERI 4486
Query: 4463 ERNSQFTSWVFNG-----RPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEV 4517
++ + +G + + G F P+ ++TA RQ + +AN W+L+ + L V
Sbjct: 4487 KQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQAN-SWSLEELCLEVNV 4545
Query: 4518 TKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIYAENNTLR 4577
T + A V GL L+GA + + L + L + +R + NT +
Sbjct: 4546 TTSQGATLDAC---SFGVTGLKLQGATCNNNKLSLSNAISTAL--PLTQLRWVKQTNTEK 4600
Query: 4578 DPRFYSCPIYKKPVRTDLNYIAAVDLRTAQTPEHWVLRGVALLC 4621
+ P+Y R DL + ++ T + P + RGVA+LC
Sbjct: 4601 KASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVLC 4644
Score = 51.6 bits (122), Expect = 2e-05
Identities = 124/650 (19%), Positives = 255/650 (39%), Gaps = 79/650 (12%)
Query: 238 TDYLTLANNPETLGKIEDCMKVWIKQTEQVLAENNQLLKEADDVGPRAELEHWKKRLSKF 297
TD+ +P L +++ + WI++ ++V +L ++ E+ W
Sbjct: 230 TDFGDKVEDPTFLNQLQSGVNRWIREIQKV----TKLDRDPASGTALQEISFWLNLERAL 285
Query: 298 NYLLEQLKSPDVKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLEKCCDP 357
+ E+ +SP+V L +L K + D + A D + D
Sbjct: 286 YRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFP-LNDL 344
Query: 358 LYSSDPLSMMDAIPTLINAIKMI----YSISHYYNTSEKIT----SLFVKV--TNQIISA 407
L +++ + A+ + ++ I Y I E I+ S +KV T +++
Sbjct: 345 LSATELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHV 404
Query: 408 C-----KAYITNNGTASIWNQPQDVVEEKILSAIKLKQEYQLCFHKTKQKLKQNPNAKQF 462
K + W+ + ++ + +K K+E L K + NP ++
Sbjct: 405 AYEEFEKVMVACFEVFQTWDDEYEKLQVLLRDIVKRKREENL-----KMVWRINPAHRKL 459
Query: 463 DFSEMYIFGKFETFHRRLAKIIDIFTTLKTYSVLQDSTIEGLEDMATKYQGIV------- 515
+ + KF H +L +I + +V Q + E E K ++
Sbjct: 460 Q-ARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADAN 518
Query: 516 -------ATIKKKEYNFLDQRKMD---FDQDYEEFCKQTNDLHNELRKFMDVTFAKIQNT 565
A KE + LD K ++ + + ++ + + + + +N
Sbjct: 519 AIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNA 578
Query: 566 NQALRMLKKFERLNI-PNL-GIDDKYQL-ILENYGADIDMISKLYTKQKYDPPLA----- 617
N+ R+ +F L + P++ G +YQ +++ DI+ + + K +Y A
Sbjct: 579 NEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKF-KVQYPQSQACKMSH 637
Query: 618 -RNQPPIAGKILWARQLFHRIQQPMQLFQQHPAVLSTAEAKPI----IRSYNRMAKVLLE 672
R+ PP++G I+WA+Q+ ++ M+ + VL + ++ ++ L
Sbjct: 638 VRDLPPVSGSIIWAKQIDRQLTAYMKRVED---VLGKGWENHVEGQKLKQDGDSFRMKLN 694
Query: 673 FEVLFHRAWLRQIEEIHVGLEASLLV--------KAPGTGELFVNFDPQILILFRETECM 724
+ +F W R++++ ++G+ + + +L VNF P+I+ L +E +
Sbjct: 695 TQEIFD-DWARKVQQRNLGVSGRIFTIESTRVRGRTGNVLKLKVNFLPEIITLSKEVRNL 753
Query: 725 AQMGLEVSPLA--TSLFQKRDRYKRNFSNMKMMLAEYQRVKSKIPAA-IEQLIVPHLAKV 781
+G V PLA Q Y S ++ + Y+R K+ L+V L K
Sbjct: 754 KWLGFRV-PLAIVNKAHQANQLYPFAISLIE-SVRTYERTCEKVEERNTISLLVAGLKKE 811
Query: 782 DEALQPGLAALTWTSLNIEAYLENTFAKIKDLELLLDRVNDL--IEFRID 829
+AL AL W S ++ Y++ + + + ++V+DL IE +ID
Sbjct: 812 VQALIAEGIALVWESYKLDPYVQRLAETVFNFQ---EKVDDLLIIEEKID 858
>gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]
Length = 4314
Score = 1184 bits (3063), Expect = 0.0
Identities = 934/3614 (25%), Positives = 1661/3614 (45%), Gaps = 214/3614 (5%)
Query: 1105 NYYKNVSENKEIVKLVSVLSTIINSTKKEVIT----SMDCFKRYNHIWQKGKEEAIKTFI 1160
N +K V E + S+ S +I+ +T + D F+R + + + KE + +
Sbjct: 811 NQFKGVGEAGD----ESIFSIMIDRNASGFLTIFSKAEDLFRRLSAVLHQHKEWIVIGQV 866
Query: 1161 TQSPLLS-------EFESQILYFQNLEQEINAEPEYVCVGSIALYTADLKFALTAETKAW 1213
L+ ++E + +E+ P V V + + +K + +
Sbjct: 867 DMEALVEKHLFTVHDWEKNFKALKIKGKEVERLPSAVKVDCLNINCNPVKTVIDDLIQKL 926
Query: 1214 MVVIGRHCNKKYRSEMENIFMLIEEFNKKLN---RPIKDLDDIRIAMAALKEIREEQISI 1270
++ K ++ + I + E + L + ++++ D + + L+E + E +
Sbjct: 927 FDLLVLSLKKSIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSKLQERKPEIL-- 984
Query: 1271 DFQVGPIEESYALLNRYGLLIAREEIDKVDTLHYAWEKLLARAGEVQNKLVSLQPSFKKE 1330
P+ + NR +A ++ + L W+K Q + K
Sbjct: 985 -----PLFQEAEDKNRLLRTVAGGGLETISNLKAKWDKFELMMESHQLMIKDQIEVMKGN 1039
Query: 1331 LISAVEVFLQDCHQFYLDYDLNGPMASGLKPQE-----ASDRLIMFQN-QFDNIYRKYIT 1384
+ S ++++ Q+ +F +D P ++ + S +LI + +FD++
Sbjct: 1040 VKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSAKLIKEKKIEFDDLEVTRKK 1099
Query: 1385 YTGGEELFGLPATQYPQLLEIKKQLNLLQKIYTLYNSVIETVNSYYDILWSEVNIEKINN 1444
F L + I K + +I+ Y + + W +
Sbjct: 1100 LVDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGFQEMANEDWITFRTKTYLF 1159
Query: 1445 E--LLEFQNRCRKLPRALKDWQAFLDLKKIIDDFSECCPLLEYMASKAMMERHWERITTL 1502
E L+ + +R RK+ + + L+ +D + P+L+Y+ + + HW + L
Sbjct: 1160 EEFLMNWHDRLRKVE---EHSVMTVKLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFRL 1216
Query: 1503 TGHSLDVGNESFKLRNIMEAP--LLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTF 1560
G E +++ ++ +++D+ A E I + L+++ F
Sbjct: 1217 LGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQGEVTIREALRELDLWGVGAVF 1276
Query: 1561 TFGSFK-TRGELLLRGDSTSEIIANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNST 1619
T ++ ++ + +I+ + D+ LL SL + Y F+ ++ W + L+
Sbjct: 1277 TLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELD 1336
Query: 1620 DIIESWMTVQNLWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCC 1679
+ +++ +Q W+YLE +F G LPKE RF+ +D+ + IMT + V
Sbjct: 1337 EYLQNLNHIQRKWVYLEPIFGRG----ALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLT 1392
Query: 1680 VGDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQ 1739
LL +LDQL+ CQKSL +LE+KR FPRF+F+ D LLEILGQ+++ IQ
Sbjct: 1393 THAGIRNSLLT-ILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQ 1451
Query: 1740 AHLLNVFDNIKSVKFHEKIYDRILSISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSS 1799
+HL +F I SV F EK I ++ S EGE + V NVE WLN L E + +
Sbjct: 1452 SHLKKLFAGINSVCFDEKS-KHITAMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMKKT 1510
Query: 1800 LHLVIRQAAANIQETGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEALRNAKFDKKIMQKT 1859
L ++++ + + + L FP+Q+ L Q+ +T D E A+++ + Q
Sbjct: 1511 LEQLLKECVTTGRSSQGAVDPSL--FPSQILCLAEQIKFTEDVENAIKDHSLHQIETQLV 1568
Query: 1860 NQAFLELLNTLIDVTTRDLSSTE----RVKYETLITIHVHQRDIFDDLCHMHIKSPMDFE 1915
N+ LE T ID ++ D +TE +K + LI +H D+ L + + + D+
Sbjct: 1569 NK--LEQY-TNIDTSSEDPGNTESGILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWA 1625
Query: 1916 WLKQCRFYFNEDSDKMMIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMG 1975
W KQ RFY D + + D F Y E+ G +LV TPLTD+CY+TL QA+ M +G
Sbjct: 1626 WKKQLRFYMKSDHT-CCVQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLG 1684
Query: 1976 GAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFN 2035
G P GPAGTGKTE+ K +G LG+ V+VFNC + +D + +GRIF GL + G+WGCFDEFN
Sbjct: 1685 GNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFN 1744
Query: 2036 RIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNP---GYAGRQE 2092
R++ VLS + QI I K H+ G V +N G+F+TMNP GY GRQ+
Sbjct: 1745 RLEESVLSAVSMQIQTIQDALKNHRTVCELL-GKEVEVNSNSGIFITMNPAGKGYGGRQK 1803
Query: 2093 LPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYD 2152
LP+NLK FR VAM PD ++I V L S GF D VL+RK ++ L E L+ Q HYD
Sbjct: 1804 LPDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYD 1863
Query: 2153 FGLRNILSVLRTLG-AAKRANPMDT-----ESTIVMRVLRDMNLSKLIDEDEPLFLSLIE 2206
+GLR + +VLR G ++ N T ES IV++ LR +SK D F +LI+
Sbjct: 1864 WGLRALKTVLRGSGNLLRQLNKSGTTQNANESHIVVQALRLNTMSKFTFTDCTRFDALIK 1923
Query: 2207 DLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGA 2266
D+FP I L + Y EL AA+ + EEA P K ++L+E R G++ +GPSGA
Sbjct: 1924 DVFPGIELKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGA 1983
Query: 2267 GKTTCIHTLMRAMTDCGKPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLR 2326
GK+T L A+ GK ++ MNPKA+ Q+ G +D+ T +W+DG+ + R+ +R
Sbjct: 1984 GKSTLWRMLRAALCKTGKVVKQYTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVR 2043
Query: 2327 AKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNAS 2386
+ WII DG +D WIE+LNSVLDDN+ LT+ +G+RI PN +FE H++ AS
Sbjct: 2044 EPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCAS 2103
Query: 2387 PATVSRNGMVFMSSSILDWSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQNLEYK 2446
PAT+SR GM+F+S D + +++ +L+ + + L + F ++ ++ +Y
Sbjct: 2104 PATISRMGMIFLSDEETDLNSLIKSWLRNQPAEYRNNLENWIGDYFEKALQWVLKQNDYV 2163
Query: 2447 MEVLEAFVITQSINMLQGLIPLKEQGGEVSQAHLGRLFVFALLWSAGAALELDGR----R 2502
+E + ++ L G E F+ L+ G L + R +
Sbjct: 2164 VETSLVGTVMNGLSHLHGCRDHDE-------------FIINLIRGLGGNLNMKSRLEFTK 2210
Query: 2503 RLELWLRSRPTGTLELPPPAGPGDTAFDYYVAPDGTWTHWNTRTQEYLYPSDTTPEYGSI 2562
+ W R P P P DT YY + G + + E L D +
Sbjct: 2211 EVFHWARESP------PDFHKPMDT---YYDSTRGRLATYVLKKPEDLTADDFSNGLTLP 2261
Query: 2563 LVPNVDNVR-TDFLIQTIAKQGK-AVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFS 2620
++ D R D+ ++ K +L+G +G K ++++ S+ I +++ S
Sbjct: 2262 VIQTPDMQRGLDYFKPWLSSDTKQPFILVGPEGCGKGMLLRYAFSQL--RSTQIATVHCS 2319
Query: 2621 SATTPLMFQRTIES---YVDKRMGTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVR 2677
+ TT + + + G Y P +++ +++ D+N+P +++WG ++
Sbjct: 2320 AQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQ 2379
Query: 2678 QLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGG-GRNDIPQRLKRQFSIFNCTLPSEAS 2736
Q++ GFY ++ E+ + +IQ +A+M G GR+ + R + + P
Sbjct: 2380 QVLTYQGFY--DENLEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQ 2437
Query: 2737 VDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKF------HY 2790
+ I+G + + + + S +K+ L + Q+ + AKF HY
Sbjct: 2438 LQTIYGAY-LEPVLHKNLKNHSIWGSSSKIYLLAGSMVQVYE----QVRAKFTVDDYSHY 2492
Query: 2791 VFNLRDLSRVWQGMLNTTSE--VIKEPND-LLKLWKHECKRVIADRFTVSSDVTWFDKAL 2847
F L++ G+ E P D +L++ +E +R+ D+ + ++ FD L
Sbjct: 2493 FFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIIL 2552
Query: 2848 VSLVEEEFGEEKKLLVDCGIDTYFVDFLRDAPEAAGETSEEADAETP--KIYEPIESFSH 2905
S+ + ++G + ++D D+++V + A +G + P K + S +
Sbjct: 2553 TSVFQGDWGSD---ILDNMSDSFYVTW--GARHNSGARAAPGQPLPPHGKPLGKLNS-TD 2606
Query: 2906 LKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVGVGGSGKQSL 2965
LK+ + L Y +D++ F + + ++ +I RV+ P G+ LL G G G++++
Sbjct: 2607 LKDVIKKGLIHYGRD--NQNLDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTI 2664
Query: 2966 TRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDESFLE 3025
T L S + G V F ++R Y DLK + + AG + + + + D + +FLE
Sbjct: 2665 TSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLE 2724
Query: 3026 YMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNENLHDYFMSRVRQNLHIV 3085
+N++LSSGEV L+ +E++ + L ++ + +YF R++QNLHIV
Sbjct: 2725 MINSLLSSGEVPGLYTLEELEPLLLPLKDQASQD-----GFFGPVFNYFTYRIQQNLHIV 2779
Query: 3086 LCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSYDIDCSLEIKKEV 3145
L F PAL C + W W ++ + E + KK
Sbjct: 2780 LIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRK 2839
Query: 3146 VQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTLANRMNT 3205
+ + D K ++ TP Y++F+ Y I K E+ + +
Sbjct: 2840 EEKKKNSVDPDFLKSFLLIHESCKAYGATPSRYMTFLHVYSAISSSKKKELLKRQSHLQA 2899
Query: 3206 GLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDR 3265
G+ KL EA V L+++ + L+ D+AD L+ +T+ Q A + K E++++K R
Sbjct: 2900 GVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHR 2959
Query: 3266 AQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDC 3325
V I + K +++L+ +P + EA+ A+ I+P ++ +R+L PP +I I++
Sbjct: 2960 IAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEG 3019
Query: 3326 VLLLFQRKVSAVKIDLEKSCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSP- 3384
VL L SW + +++ F I++E+ E +
Sbjct: 3020 VLRLM-------------GIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEEL 3066
Query: 3385 -YFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQENRHLLAMQD 3443
+ ++ + AKR A L +W KA + + + + PL+ E+
Sbjct: 3067 LFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDR 3126
Query: 3444 LQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLAGEKERW 3503
+K + L+ ++ ++ +++ +E L + + + ++ A LI+ L E +RW
Sbjct: 3127 KRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRW 3186
Query: 3504 TEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLNDWRKEMKARKIPFGKNL-N 3562
Q E + L LA AF++Y + R L +W K K + L
Sbjct: 3187 NAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWTKSAGLEKFDLRRFLCT 3246
Query: 3563 LSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKA------SRY-PLLIDPQTQGKIWIK 3615
SE LI W +GLP+DDLSI+N +++ + SR P LIDP +Q W+K
Sbjct: 3247 ESEQLI-------WKSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLK 3299
Query: 3616 NKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTGSTF 3675
+ L++ + F LE ++ G+ L+I+++ + ++P L +L R+ + G +
Sbjct: 3300 THLKDSRLEVINQQDSNFITALELAVRFGKTLIIQEM-DGVEPVLYPLLRRDLVAQGPRY 3358
Query: 3676 KVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTE 3735
V++GDK +D + FRL+++T+ PNP P+ ++ + ++FT T GL QLL I E
Sbjct: 3359 VVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHE 3418
Query: 3736 KQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEV 3795
K +LE+++T L++ K ++ +LE++LL L ++QG+++E++ LI L+ TK ++ +
Sbjct: 3419 KPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALI 3478
Query: 3796 TQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSL 3855
+ L+ S + ++ ++ R+ Y P+A S +YF+I+++ +N MY+ SL FL LF +L
Sbjct: 3479 QESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRAL 3538
Query: 3856 ARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEF 3915
S T +RI ++I + + VY+Y R L++ + +F L + + + +
Sbjct: 3539 QNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDT 3598
Query: 3916 LTLIKGGASL-----------DLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISR 3964
T + G L L + + W + + L L + F D
Sbjct: 3599 FTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQTLCFEDA------ 3652
Query: 3965 NEKMWKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKY 4024
+W+ +++ E+E P+ K + F+++L++++ PDR + + ++G K
Sbjct: 3653 --ALWRTYYNNSMCEQE-FPSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKE 3709
Query: 4025 AEGVILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKIETRY--VSMGQGQEVH 4082
+ L+L++ ++E+ P++ ++S G+DP+ + L + Y V+MGQGQ
Sbjct: 3710 VSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQELANAERSGECYHQVAMGQGQADL 3769
Query: 4083 ARKLLQQTMANGGWALLQNCHLGLDFMDELMDIIIETELVHDAFRLWMTTEAHKQFPITL 4142
A ++L++ NG W L+N HL + ++ +++ + T D FRLW+T E H F L
Sbjct: 3770 AIQMLKECARNGDWLCLKNLHLVVSWL-PVLEKELNTLQPKDTFRLWLTAEVHPNFTPIL 3828
Query: 4143 LQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSGSQWKPMLYAVAFLHSTVQERRKFG 4202
LQ S+K + P GL+ L RTY + + + + L+++A+ H+ QERR +
Sbjct: 3829 LQSSLKITYESPPGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLAWFHAACQERRNYI 3888
Query: 4203 ALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDDYDKR 4262
GW YEF+ +D A I D K V W + ++ YGGR+ + +D R
Sbjct: 3889 PQGWTKFYEFSLSDLRAGYNIIDRLFDG---AKDVQWEFVHGLLENAIYGGRIDNYFDLR 3945
Query: 4263 LLNTFAKVWFSE------NMFGPDFSFYQGYNIPKCSTVDNYLQYIQSLPAYDSPEVFGL 4316
+L ++ K +F+ N F ++P+ ++ +Y I+ +P D P FGL
Sbjct: 3946 VLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGL 4005
Query: 4317 HPNADITYQSKLAKDVLDTILGIQPKDTSGGGDETREAVVARLAD--DMLEKLPPDYVPF 4374
N + Q ++ V+ L I + + G RE L+ ++ +KL +
Sbjct: 4006 PANIARSSQRMISSQVISQ-LRILGRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNLI 4064
Query: 4375 EVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDC 4434
K P+ F+ E R++ V +L L I GT ++S ++
Sbjct: 4065 HQKVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASA 4124
Query: 4435 MFDARIP-AWWKKASWISSTLGFWFTELIERNSQFTSWVFNGRPHCFW-----MTGFFNP 4488
+ + + P AW K L + L+ R +WV ++ F+P
Sbjct: 4125 LLNQKCPLAWQSKWEGPEDPLQY-LRGLVARALAIQNWVDKAEKQALLSETLDLSELFHP 4183
Query: 4489 QGFLTAMRQEITRANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKR 4548
FL A+RQE RA G ++D++ V W K + + + + GL LEG +D
Sbjct: 4184 DTFLNALRQETARA-VGRSVDSLKF---VASW-KGRLQEAKLQ-IKISGLLLEGCSFDGN 4237
Query: 4549 NMKLIESKPKVLFELMPVIRIYAENNT---LRDPRFYSCPIYKKPVRTDLNYIAAVDLRT 4605
+ + + ++P + + S P+Y R + +D+
Sbjct: 4238 QLSENQLDSPSVSSVLPCFMGWIPQDACGPYSPDECISLPVYTSAERD--RVVTNIDVPC 4295
Query: 4606 AQTPEHWVLRGVAL 4619
+ W+ G AL
Sbjct: 4296 GGNQDQWIQCGAAL 4309
Score = 45.1 bits (105), Expect = 0.002
Identities = 87/500 (17%), Positives = 206/500 (41%), Gaps = 50/500 (10%)
Query: 341 AKDNVKYLYTL-EKCCDPLYSSDPLSMMDAIPTLINAIKMIYSISHYYNTSEKITSLFVK 399
+K+ Y L E Y+ D LS+++ + + ++ + S +
Sbjct: 191 SKERANYFKELFETIAREFYNLDSLSLLEVVDLVETTQDVVDDVWRQTEHDHYPESRMLH 250
Query: 400 VTNQIISACKAYITNN-GTASIWNQPQDVVEEKILSAIKLKQEYQL-CFHKTKQKLKQN- 456
+ + I + ++ GT ++W P +V+E + + I + +++ + C H T Q ++
Sbjct: 251 LLDIIGGSFGRFVQKKLGTLNLWEDPYYLVKESLKAGISICEQWVIVCNHLTGQVWQRYV 310
Query: 457 PNAKQFDFSEMYIFGKFETFHRRLAKIIDIFTTLKTYSVLQDSTIEGLEDMATKYQGIVA 516
P+ + +E Y + +RL +++ I T + + ++ E + + ++
Sbjct: 311 PHPWK---NEKYFPETLDKLGKRLEEVLAIRTIHEKFLYFLPASEEKIICLTRVFEPFTG 367
Query: 517 TIKKKEYNFLDQR--KMDFDQDYEEFCKQTNDLHNELRKFMDVTFAKIQNTNQAL--RML 572
+ +YN + K Q + + +L+ ++ ++IQ++ Q L L
Sbjct: 368 -LNPVQYNPYTEPLWKAAVSQYEKIIAPAEQKIAGKLKNYI----SEIQDSPQQLLQAFL 422
Query: 573 KKFERLNIPNLGID---DKYQLI------LENYGADIDMISKLYTKQKYDPPLARNQPPI 623
K E + P + + ++ L+ ++++ D + + P +N +
Sbjct: 423 KYKELVKRPTISKELMLERETLLARLVDSIKDFRLDFENRCRGIPGDASGPLSGKNLSEV 482
Query: 624 AGKILWARQLFHRIQQPMQLFQQHPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRA--- 680
I+W RQL ++ +++ + A+LS P R +++ AK LL+ L+ +
Sbjct: 483 VNSIVWVRQLELKVDDTIKIAE---ALLSDL---PGFRCFHQSAKDLLDQLKLYEQEQFD 536
Query: 681 -WLRQIEEIHVGLEASLLVKA--------PGTGELFVNFDPQILILFRETECMAQMGLEV 731
W R I+ + L ++A G L V++ +++IL RE ++ +G +
Sbjct: 537 DWSRDIQSGLSDSRSGLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLSALGFVI 596
Query: 732 SPLATSLFQKRDRYKRNFSNMKMMLAEY-----QRVKSKIPAAIEQ-LIVPHLAKVDEAL 785
+ ++ + +K + Y Q ++S+ P ++ L + K +A
Sbjct: 597 PAKIQQVANIAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAG 656
Query: 786 QPGLAALTWTS-LNIEAYLE 804
G + +TW + +E Y++
Sbjct: 657 SGGKSQITWDNPKELEGYIQ 676
>gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]
Length = 3092
Score = 916 bits (2367), Expect = 0.0
Identities = 655/2120 (30%), Positives = 1041/2120 (49%), Gaps = 172/2120 (8%)
Query: 1004 QNSLPIFRASVTLAIPNIVMAPALEDVQQTLNKAVECIISVPKGVRQWSSELLSKKKIQE 1063
Q LPIF+ +T + P +D++ + VE I + V+ S L
Sbjct: 320 QQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPSWLSG------ 373
Query: 1064 RKMAALQSNEDSDSDVEMGENELQ---DTLEIASVNLPIPVQTKNYYKNVSENKEIVKLV 1120
++ + D E+ E+ L DTL+ A+V+ + K+Y V
Sbjct: 374 -------TSTPVNLDTELPEHVLHWAVDTLK-AAVHRNLEGARKHYETYV---------- 415
Query: 1121 SVLSTIINSTKKEVITSMDCFKRYNHIWQKGKEEAIKTFITQSPLLSEFESQILYFQNLE 1180
++YN + E I+TF T+ E+ I F +L
Sbjct: 416 ---------------------EKYNWLLDGTAVENIETFQTEDHTFDEYTEFIEKFLSLA 454
Query: 1181 QEINAEPEYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNKKYRSEMENI---FMLIE 1237
EI P+++ + L DLK LT + KA+ ++ KYR E E I F I+
Sbjct: 455 SEIMLLPQWIHYTMVRLDCEDLKTGLTNKAKAFANILLNDIASKYRKENECICSEFEAIK 514
Query: 1238 EFNKKLNRPIKDLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAREEID 1297
E K+ +++ D+ + + + E++ + Q + SY L + + +E
Sbjct: 515 EHALKVPETTEEMMDLISYVEKARTVGIEELILRIQESKRQMSYFL----DVFLFPQEDL 570
Query: 1298 KVDTLHYAWEKLLARAGEVQNKLVSLQPSFKK-ELISAVEVFLQDCHQFYLDYDLNGPMA 1356
++ W + + + ++L+ K+ EL++ E + + + + A
Sbjct: 571 ALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIEKESRRMEEFTEFA 630
Query: 1357 SGLKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIY 1416
+ Q+ + Q + EELF T+YP+L ++K + QK +
Sbjct: 631 ELERMQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKFF 690
Query: 1417 TLYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKKIIDDF 1476
+ + D + ++N E + ++ EF R++ + LK +Q LKK + +
Sbjct: 691 NFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFS---REIFKTLKFFQT--KLKKELQEK 745
Query: 1477 SECCPLLEYMASKA--------------MMERHWERITTLTGHSLDVGNESFKLRNIMEA 1522
+ K M RHW++I+ + G+ L + LR +++
Sbjct: 746 RKAARKRSLEEEKIEEEPKDNATITMCRMRARHWKQISEIVGYDL-TPDSGTTLRKVLKL 804
Query: 1523 PLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEII 1582
L Y E+ E I A KE +E+ + +I W++ F ++ G +L S EI
Sbjct: 805 NLTPYLEQFEVISAGASKEFSLEKAMNTMIGTWEDIAFHISLYRDTGVCIL--SSVDEIQ 862
Query: 1583 ANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGG 1642
A ++D ++ ++ + + PF+ +I+ W L + I+ W+ VQ W+YLE +F
Sbjct: 863 AILDDQIIKTQTMRGSPFIKPFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEPIFCSE 922
Query: 1643 DIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKS 1702
DI +Q+P+E ++F +D+ W IM + P V+ L + L + + LE K
Sbjct: 923 DIMQQMPEEGRQFQTVDRHWRDIMKFCAKDPKVL-AATSLTGLLEKLQNCNELLEKIMKG 981
Query: 1703 LTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDRI 1762
L YLEKKRL FPRFFF+S+ +LEIL + D +Q HL F+ I ++F + I
Sbjct: 982 LNAYLEKKRLFFPRFFFLSNDEMLEILSETKDPLRVQPHLKKCFEGIAKLEFLPNL--DI 1039
Query: 1763 LSISSQEGETIELDKPVM---AEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLT 1819
++ S EGE +EL + A G VE WL + + S+H VI AAA +
Sbjct: 1040 KAMYSSEGERVELIALISTSAARGAVEKWLIQVEDLMLRSVHDVI--AAARLAYPESARR 1097
Query: 1820 EFLSSFPAQVGLLGIQMIWTRDSEEALRNAKFDKKIMQKTNQAFLELLNTLIDVTTRDLS 1879
+++ +P QV L QM WT +++E + K K Q LN ++++ LS
Sbjct: 1098 DWVREWPGQVVLCISQMFWTSETQEVISGGTEGLKKYYKELQ---NQLNEIVELVRGKLS 1154
Query: 1880 STERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVA 1939
R L+TI VH RD+ D+ M + DF WL Q R+Y+ ++ ++ I +V
Sbjct: 1155 KQTRTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRYYWENENARVRIINCNVK 1214
Query: 1940 FIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGK 1999
+ Y E+LG + RLVITPLTDRCY TL A +++GGAP GPAGTGKTETTKD+ + L
Sbjct: 1215 YAY--EYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAV 1272
Query: 2000 YVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEH 2059
VVFNCSD +D+ +G+ FKGLA SG+W CFDEFNRI+L VLSV AQQI I ++
Sbjct: 1273 QCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQK 1332
Query: 2060 KKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKL 2119
F+F +G + +NP + +TMNPGYAGR ELP+NLK+ FR+VAMMVP+ +I + L
Sbjct: 1333 LVVFVF-EGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISL 1391
Query: 2120 ASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTEST 2179
S GF++ L+ K Y+LC EQLS Q HYD+G+R + +VL G K P + E
Sbjct: 1392 YSYGFLNARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDI 1451
Query: 2180 IVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPE-LEAAISRQVEEAGLINH 2238
+++R ++D+N K + D PLF + DLFP I L +A Y E LE A E + N
Sbjct: 1452 LLLRSIKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECA----HEACNVHNL 1507
Query: 2239 PPWKL---KVIQLFETQRVRHGMMTLGPSGAGKTTCIHTL---MRAMTDCGKPHRE---- 2288
P K K+IQ +E VRHG M +G A KT +H L + M + G E
Sbjct: 1508 QPVKFFLEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIY 1567
Query: 2289 MRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIEN 2348
+NPK+IT Q+FG+ D +++WTDGI + +R+ ++ + W++ DGP+D +WIE+
Sbjct: 1568 RTVNPKSITMGQLFGQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPIDTLWIES 1627
Query: 2349 LNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPI 2408
+N+VLDDNK L L +G+ I M+P +IFE ++ ASPATVSR GM+++ S L W P+
Sbjct: 1628 MNTVLDDNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPL 1687
Query: 2409 LEGFLKKR-----SPQEAEILRQLYTESFP-------DLYRFCIQNLEYKMEVLEAFVIT 2456
+ +L P+ +LR L+ P +L++ ++L+ +IT
Sbjct: 1688 VSSWLNSLKGPLCEPEYQALLRGLFAWLIPPSLNQRVELFQLNYLYTTIVSKILK-ILIT 1746
Query: 2457 QSINMLQGLIPLKEQGGEVS-QAHLGRLFVFALLWSAGAALELDGRRRLELWLRSRPTGT 2515
I+ +PLK Q + H F+F+L+WS G + + DGRR + ++R G
Sbjct: 1747 FRISNYFKYVPLKTQCTFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIRLIILGK 1806
Query: 2516 LE---LPPPAGPGDTAFD---------YYVAPDGTWTHWNTRTQEYLYPSDTTPEYGSIL 2563
+ +P G + FD Y + G W HWN + D + I+
Sbjct: 1807 DDENPVPDSVGKWECPFDEKGLVYDYMYELKNKGRWVHWNELIKN-TNLGDKQIKIQDII 1865
Query: 2564 VPNVDNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIKG-FMSKYDPECHMIKSLNFSSA 2622
VP +D +R FL+ K +L +G GT K+V +K M+ + + + +N S+
Sbjct: 1866 VPTMDTIRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLSAR 1925
Query: 2623 TTPLMFQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQ 2682
T+ Q I + +DKR +GPP GKK +FIDD+NMP + ++G Q E++RQ +
Sbjct: 1926 TSANQVQNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFFDC 1985
Query: 2683 NGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIFG 2742
+Y+L+ + T +VDI+ +AAM PGGGRN + R R F+I + S+ ++ +IF
Sbjct: 1986 GHWYDLKDTSKIT-LVDIELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVRIFS 2044
Query: 2743 VIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQ 2802
I V Y F E ++V T +++ + +LPTP K HY FNLRD SRV +
Sbjct: 2045 SI-VAFYLRTHEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRVIR 2103
Query: 2803 GMLNTTSEVIKEPNDLLKLWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGEEKKLL 2862
G L + + + +++L+ HE RV DR D W + +++++ F E
Sbjct: 2104 GCLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKE----- 2158
Query: 2863 VDCGIDTYFVDFLRDAPEAAGETSEE------ADAETP------KIYEPIESFSHLKERL 2910
++ F + A T E+ D P ++Y I + H + +
Sbjct: 2159 ------SFHSIFSHLRKQNAPVTEEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVV 2212
Query: 2911 NMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLAS 2970
+ L YN++ + M++V F + HL +I RV++ GNALLVG+GGSG+QSLTRLA+
Sbjct: 2213 DQCLDEYNQTHK-TRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLAT 2271
Query: 2971 FIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKD-ESFLEYMNN 3029
+A FQ +++SY + ED+K +T DN+ K E L Y+N+
Sbjct: 2272 SMAKMHIFQPEISKSYGMNEWREDMKSFIAVP------VTNRIVDNKSKILEKRLRYLND 2325
Query: 3030 VLSSGEVSN----LFARDEI 3045
+ N LF +D++
Sbjct: 2326 HFTYNLYCNICRSLFEKDKL 2345
Score = 446 bits (1146), Expect = e-124
Identities = 256/790 (32%), Positives = 415/790 (52%), Gaps = 37/790 (4%)
Query: 3860 KSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEFLTLI 3919
KS I KR+ + +H TY +Y R L+E+ K LF+ LL + + R ++++E + L+
Sbjct: 2312 KSKILEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLL 2371
Query: 3920 KGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIWFDKENPE 3979
GG SL P P+ W+ D +W + S+ F + + W+ +D + P
Sbjct: 2372 TGGVSLKSAEKNPDPT-WLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIYDSKEPH 2430
Query: 3980 EEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLEKTWEES 4039
P DK+L+ ++++++R PD+ Y+ D +G+K+ E DL K++ +S
Sbjct: 2431 NAKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDS 2490
Query: 4040 DPRTPLICLLSMGSDPTDSIIALGKRLKI---ETRYVSMGQGQEVHARKLLQQTMANGGW 4096
+ PLI +LS G+DP S++ + + + +S+GQGQ A K+++ + G W
Sbjct: 2491 NCTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTW 2550
Query: 4097 ALLQNCHLGLDFMDELMDII--IETELVHDAFRLWMTTEAHKQFPITLLQMSIKFANDPP 4154
LQNCHL + +M L I +E + +FRLW+T+ +FP+T+LQ +K N+PP
Sbjct: 2551 VCLQNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSKFPVTILQNGVKMTNEPP 2610
Query: 4155 QGLRAGLKRTYSGVSQDLLDVSSGSQ-----WKPMLYAVAFLHSTVQERRKFGALGWNIP 4209
GLR L ++Y + G + W+ +L+ V F H+ VQER+KFG LGWNIP
Sbjct: 2611 TGLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWNIP 2670
Query: 4210 YEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDDYDKRLLNT--- 4266
Y FN++D +++ +Q +++ D + + I Y+ GE YGGRVTDD+D+RLL T
Sbjct: 2671 YGFNESDLRISIRQLQLFINEYDT---IPFEAISYLTGECNYGGRVTDDWDRRLLLTMLA 2727
Query: 4267 -FAKVWFSENMFGPDFSFYQ--GYNIPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNADIT 4323
F ++ EN P + F Y P T ++Y+++I+ LP PE+FGLH N DI+
Sbjct: 2728 DFYNLYIVEN---PHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHENVDIS 2784
Query: 4324 YQSKLAKDVLDTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDYVPFEVKERLQKM 4383
+ K + +++L Q G + + ++ + D+L KLP D+ E+ R +
Sbjct: 2785 KDLQQTKTLFESLLLTQGGSKQTGASGSTDQILLEITKDILNKLPSDF-DIEMALRKYPV 2843
Query: 4384 GPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDARIPAW 4443
+ MN L QE++R ++ +R+TL +L+ AI G ++M L + ++P
Sbjct: 2844 RYEESMNTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEI 2903
Query: 4444 WKKASWIS-STLGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQGFLTAMRQEITRA 4502
W K S+ S LG + T+ + R + W +G+P FW++GFF Q FLT Q R
Sbjct: 2904 WAKRSYPSLKPLGSYITDFLARLNFLQDWYNSGKPCVFWLSGFFFTQAFLTGAMQNYARK 2963
Query: 4503 NKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFE 4562
+ +L E D P +GVY++GLYL+GA WD+ + L E PK+LF+
Sbjct: 2964 ---YTTPIDLLGYEFEVIPSDTSDTSPEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFD 3020
Query: 4563 LMPVIRIY-AENNTLRDPRFYSCPIYKKPVRT--------DLNYIAAVDLRTAQTPEHWV 4613
LMP+I I + + + Y CP+YK R N++ A+ L+T Q HW+
Sbjct: 3021 LMPIIWIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWI 3080
Query: 4614 LRGVALLCDV 4623
RGVALLC +
Sbjct: 3081 KRGVALLCQL 3090
>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
sapiens]
Length = 4515
Score = 776 bits (2003), Expect = 0.0
Identities = 513/1902 (26%), Positives = 912/1902 (47%), Gaps = 239/1902 (12%)
Query: 2928 MVFFADAMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYN 2987
++ F D + +SR + N +G+ G GK++ LA ++ +++ ++
Sbjct: 2642 LIDFTDKSLFYRLLSRELE----NCFQIGIDGCGKKTCATLACYLTDNKLYRVPISHKCA 2697
Query: 2988 TSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDE 3047
E K ++ AG +GK + + I+ +SFLE +N ++SSG + +LF E+D
Sbjct: 2698 YIEFKEVFKKVFIHAGLKGKPTVLMVPNLNIEQDSFLEDLNYIISSGRIPDLFENVELDS 2757
Query: 3048 INSDLASVMKKEFPRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALIS 3107
I + + ++ + ++L +F R+ +NLHI + SP G FR +P++IS
Sbjct: 2758 IAMKIRYLTEQSGH--MDNRQSLLSFFQKRIYKNLHIFVIMSPEGPSFRQNCRVYPSMIS 2815
Query: 3108 GCTIDWFSRWPKDALVAVSEHFLTS-YDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQR 3166
CTIDW+ RWP++AL+ V+ FL + + +K+++ + + YF+
Sbjct: 2816 SCTIDWYERWPEEALLIVANSFLKEKVNFENRENLKEKLAPTCVQIHKSMKDLNRKYFEE 2875
Query: 3167 FRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELEA 3226
R + TP SYL F++ + I + E++T +R + GL + EA+ V + +EL
Sbjct: 2876 TGRFYYTTPNSYLQFMETFAHILRAREEEMQTKRDRFHMGLSTILEATTLVTEMQEELLI 2935
Query: 3227 KEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEA 3286
+++ + + +++++ +Q EKV+ V++ ++ V + +L++
Sbjct: 2936 LGPQVEQKTKETETLMEKLRKDSQVVEKVQMLVKQDEEIVAEEVRIVEDYAQKTANELKS 2995
Query: 3287 AKPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCT 3346
PA ++A AL + +D+A +R RPP L++ +M+ V +L Q+K
Sbjct: 2996 VLPAFDKAIVALNALDKADVAELRVYTRPPFLVLTVMNAVCILLQKK------------- 3042
Query: 3347 MPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAGL 3406
P+W + L++ FL+ L KD+I ++V L +PD+N V L
Sbjct: 3043 -PNWATAKLLLSETGFLKKLINLDKDSIPDKVFVKLKKIVTLPDFNPHKISLVSVACCSL 3101
Query: 3407 CSWTKAMASFFSINKEVLPLKANLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYE 3466
C W A+ ++ + K V P + + +N +A Q L + Q L + L +QA Y+
Sbjct: 3102 CQWVIALNNYHEVQKVVGPKQIQVAEAQNVLKIARQRLAEKQRGLQLVEEHLLFLQAAYK 3161
Query: 3467 QAMTEKQTLLEDAERCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLATA 3526
+ EKQ L + Q AS L++ L EK RW E + + + ++GD+LL+ A
Sbjct: 3162 DTVAEKQLLANRKTMASRRFQCASVLLTVLEDEKTRWQETINQIDNKLEGILGDILLSAA 3221
Query: 3527 FLSYSGPFNQEFRDLLLNDWRKEMKARKIPFGKNLNLSEMLIDAPTISEWNLQGLPNDDL 3586
+ YSG EFR L++N W I +L +++ IS W+ QGLP+
Sbjct: 3222 CIVYSGILTPEFRQLIVNKWETFCIENGISLSSKFSLIKVMAQKYEISRWHNQGLPHGQY 3281
Query: 3587 SIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESRNELQITSLNHKYFRNHLEDSLSLGRP 3646
S++N I++ ++PLLIDP Q WI+ E + LQ S+ + +E+++ G
Sbjct: 3282 SVENAILIKNGQQWPLLIDPHRQAHKWIRQMEG-SRLQKLSIEDSNYTKKIENAMKTGGS 3340
Query: 3647 LLIEDVGEELDPALDNVLERNFIKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPE 3706
+L++++ E L P L +L+++ + + ++VGD E + FRLY++T++ NP + P
Sbjct: 3341 VLLQNLLETLAPGLKAILKKDIYQKKGHYFIRVGDAEFEYNSNFRLYLSTEIDNPHFLPS 3400
Query: 3707 ISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEKERTHLMEDVTANKRRMKELEDNLLY 3766
+ ++I+FTVT +GL+DQLL V+ E LE +R+ L+E ++ + ++ELE+ L
Sbjct: 3401 VYNFVTMINFTVTFQGLQDQLLSTVVTHEVPHLEDQRSKLLESISLDAITLEELEEKTLN 3460
Query: 3767 RLTSTQGSLVEDESLIVVLSNTKRTAEEVTQKLEISAETEVQINSAREEYRPVATRGSIL 3826
L GS+++D+ ++ L +K T+ E+++++E + + E +I + R+ Y P+ATRG++L
Sbjct: 3461 LLQKALGSILDDDKIVDTLRKSKMTSNEISKRIEATKKAESEIQAIRKNYLPIATRGALL 3520
Query: 3827 YFLITEMRLVNEMYQTSLRQFLGLF-----------DLSLARSVKSP------------- 3862
YFL+ ++ +N MYQ SL F +F + S R SP
Sbjct: 3521 YFLVADLTQINYMYQFSLDWFHQVFVSSVVSKSKEQEHSFKREKVSPKEVHEFISISKEP 3580
Query: 3863 -------ITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNR------ 3909
+ K I + I+ +T ++K + L+ E K F+ L I +Q N
Sbjct: 3581 NLENEKNLLDKHIKSAIDMLTKSIFKVVSSALFNEDKLCFSFRLCTVI-MQNNANGNLIQ 3639
Query: 3910 -----VKHEEFLTLIKGGASLDLKAC-------------PPKPSKWILDITWLNLVELS- 3950
+ EE+ + G +++K+ + +W+ D W +S
Sbjct: 3640 DDIGFLPEEEWNIFLYSGILINIKSALSQSRLTSTFEIGESQHLQWLSDSRWRQCQYVST 3699
Query: 3951 KLRQFSDVLDQISRNEKMWKIW-------------FDKEN---------PEEEPLPNAYD 3988
L FS + + N W + F EN PEE L N
Sbjct: 3700 HLEPFSLLCKSLLSNVSQWDTFKNSKAVYSLISTPFSSENASLEENTKPPEETELLNENK 3759
Query: 3989 KS----------LDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLEKTWEE 4038
++ L F+RL+L++ P+ RK+I + MG KY + ++L+ ++
Sbjct: 3760 ETCNPINFPWEKLTSFQRLILVKVLRPESLNNSVRKFITEKMGNKYLQRTGVNLKDAYKG 3819
Query: 4039 SDPRTPLICLLSMGSDPTDSIIALGKRLKIETRYV---SMGQGQEVHARKLLQQTMA-NG 4094
S+ RTPLI + + G D T+ ++ + LK T +V S+G+ Q A L+ + +
Sbjct: 3820 SNARTPLILIQTHGIDLTNILLRFAQELKGTTHHVTIISLGRDQAAKAEDLILKALTKTQ 3879
Query: 4095 GWALLQNCHLGLDFMDELMDII----IETELVHDAFRLWMTTEAHKQFPITLLQMSIKFA 4150
W LQNCHL FM L I+ + FRLW++++++ FPI +L+ +K A
Sbjct: 3880 QWVFLQNCHLATSFMPRLCTIVESFNSPNVTIDPEFRLWLSSKSYSSFPIPVLKKGLKIA 3939
Query: 4151 NDPPQGLRAGLKRTY----SG-VSQDLLD-VSSGSQWKPMLYAVAFLHSTVQERRKFGAL 4204
+ PQGL++ L +T+ SG V++++ + G WK +L+++ F ++ + ER+ +G L
Sbjct: 3940 VESPQGLKSNLLQTFGCTGSGEVTEEIFENPDCGQWWKKLLFSLCFFNAVINERKNYGIL 3999
Query: 4205 GWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDDYDKRLL 4264
GWNI Y+FN +D ++ ++N L + +SW +RY+IGE+ YGGRV D++DKR L
Sbjct: 4000 GWNIAYKFNSSDLGVAIKVLENSLRG---QPSISWQALRYLIGEVIYGGRVIDNWDKRCL 4056
Query: 4265 NTFAKVWFSENMFGPDFSFYQGYNIPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNADITY 4324
T + + + DFSF + +++ +Y+ IQSLP D PEV G+HP A +
Sbjct: 4057 KTLLYKFCNPEVLKDDFSF------SRSASIKDYIHIIQSLPDDDLPEVLGIHPEAIRSC 4110
Query: 4325 QSKLAKDVLDTILGIQPKDTSGG----GDETREAVVARLADDMLEKLP------------ 4368
+ ++ ++ +QPK T+ +++++ +V + D+L++LP
Sbjct: 4111 WETQGEKFIENLIAMQPKTTTANLMIRPEQSKDELVMEILSDLLKRLPLTVEKEEIAVGT 4170
Query: 4369 ----PDYVPFEVKERLQK-MGPFQP-----MNIFLRQEIDRMQRVLSLVRSTLTELKLAI 4418
+ + E L K + P + FL+QEI R ++L ++ +L +L+LAI
Sbjct: 4171 PSTLKSMMSSSIWESLSKNLKDHDPLIHCVLLTFLKQEIKRFDKLLFVIHKSLKDLQLAI 4230
Query: 4419 DGTIIMSENLRDALDCMFDARIPAWWKKASWIS-STLGFWFTELIERNSQFTSWV----- 4472
G II+++ L + + + R+P W+K ++ S L W +LI+R + F +W
Sbjct: 4231 KGEIILTQELEEIFNSFLNMRVPTLWQKHAYRSCKPLSSWIDDLIQRLNFFNTWAKVAYT 4290
Query: 4473 ----------------------------------FNGRPHCFWMTGFFNPQGFLTAMRQE 4498
F G P +W+ FF PQ FL A+ Q+
Sbjct: 4291 AIQRRYMRFVTVWKQSIPSTSQKCKHPEDSENNFFEGFPSRYWLPAFFFPQAFLAAVLQD 4350
Query: 4499 ITRANKGWALDNM-----VLCNEVTKWMKDDI---------------SAPPTEGVYVYGL 4538
R ++G A+D + V+ N K K + SA GVY++GL
Sbjct: 4351 YGR-SRGIAVDALTFTHHVISNTTDKDEKFSVFMPKKLNIVRRAFKGSASSHTGVYIFGL 4409
Query: 4539 YLEGAGWDKRNMKLIESKPKVLFELMPVIRIY----------AENNTLRDPRFYSCPIYK 4588
++EGA W++ L +S P + P I A N T + + CP+Y+
Sbjct: 4410 FIEGARWNREQKILEDSLPLEMCCDFPDIYFLPTKISTKTPNASNQTDSELYAFECPVYQ 4469
Query: 4589 KPVRTDL--------NYIAAVDLRTAQTPEHWVLRGVALLCD 4622
P R+ + N++ +V L T + P HW+ VALLC+
Sbjct: 4470 TPERSRILATTGLPTNFLTSVYLSTKKPPSHWITMRVALLCE 4511
Score = 548 bits (1411), Expect = e-155
Identities = 355/1120 (31%), Positives = 566/1120 (50%), Gaps = 109/1120 (9%)
Query: 1401 QLLEIKKQLNLLQKIYTLYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRAL 1460
++ +I+ L L +K++ + + +++E + + + + L + L
Sbjct: 988 EISDIEGDLTLRKKLWEAQEEWKRASWEWRNSSLQSIDVESVQRNVSKLMHIISVLEKGL 1047
Query: 1461 KDWQAFLDLKKIIDDFSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIM 1520
LK+++ +F + P++ + + + RHWE + + G S+ + +++ K+ N++
Sbjct: 1048 PKSDMVTHLKQVVTEFKQELPIIIALGNPCLKPRHWEALQEIIGKSVPL-DKNCKVENLL 1106
Query: 1521 EAPLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSE 1580
+ +Y+ EI D+ SA E +E+ L ++I+ W+ T + S +
Sbjct: 1107 ALKMFQYENEINDMSTSATNEAALEKMLFKIIDFWNTTPLPLILHHTEIYSIFIIPSIDD 1166
Query: 1581 IIANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFV 1640
I A +E+S ++L ++ + + P K + +W Q L+ + +E WM Q W+YLE VF
Sbjct: 1167 ISAQLEESQVILATIKGSPHIGPIKDLVNEWDQNLTLFSYTLEEWMNCQRNWLYLEPVFH 1226
Query: 1641 GGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQ 1700
+I +QLP E + FS + W KIM++ + +Q L ++L + LE +
Sbjct: 1227 SSEIRRQLPAETELFSQVISMWKKIMSKIQNKQNALQITTSAGVL-EILQNCNIHLEHIK 1285
Query: 1701 KSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYD 1760
KSL YLE KRL FPRF+F+S+ LL+IL + + ++Q HL+ F+NIK + ++
Sbjct: 1286 KSLEDYLEVKRLIFPRFYFLSNAELLDILADSRNPESVQPHLVKCFENIKQLLIWKQDIG 1345
Query: 1761 --RILSISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQL 1818
+ + S EGE + L K + VE WL N++++ F +
Sbjct: 1346 PPAVKMLISAEGEGLVLPKKIRVRSAVEQWL-------------------VNVEKSMFDV 1386
Query: 1819 TEFLSSFPAQVGLLGIQMIWTRDSEEALRNAKFDKKIMQKTNQAFLELLNTLIDVTTRDL 1878
+ + L Q+++ D ++ ++ + ++ ++K + + L + D+ D
Sbjct: 1387 LKKERYIYNIILLFQSQIMFYNDCVKSFVSS-YSREKLEKVHAGLMCHLEEVADLVVLDT 1445
Query: 1879 SSTE-RVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITD 1937
S++ + L+ ++VH RDI +L +I + DFEW + ++ +NE + +
Sbjct: 1446 SNSRTKAILGALLILYVHCRDIVINLLLKNIFNAEDFEWTRHLQYKWNEKQKLCYVSQGN 1505
Query: 1938 VAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCL 1997
+F Y E+LGCT RLVITPLTDRC++TL +AL +++GG PAGPAGTGKTET KD+ + L
Sbjct: 1506 ASFTYGYEYLGCTSRLVITPLTDRCWLTLMEALHLNLGGCPAGPAGTGKTETVKDLAKSL 1565
Query: 1998 GKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKK 2057
GK+ VVFNC + +D++ + + F GL QSG+W CFDEFN IDL VLSV A QI I K
Sbjct: 1566 GKHCVVFNCFEDLDYKIVRKFFFGLVQSGAWSCFDEFNLIDLEVLSVIASQILTIKAAKD 1625
Query: 2058 EHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRV 2117
+ F+ +G + +N +F+TMNP Y G ELP+NLK FR VAMMVP Q+I +
Sbjct: 1626 NYSARFVL-EGKEIRINMSCAVFITMNPRYGGGVELPDNLKSLFRPVAMMVPHYQMIAEI 1684
Query: 2118 KLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKR---ANPM 2174
L S GF L+ K LY+L +QLS+Q HY+FGLR++ VL G KR
Sbjct: 1685 ILFSFGFKSANSLSGKLTNLYELARKQLSQQDHYNFGLRSLKIVLIMAGTKKREFKCLSE 1744
Query: 2175 DTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEAG 2234
E+ IV+ +R+ +L K ED PLF ++I D+FP + + K LE I ++ G
Sbjct: 1745 ADETLIVIEAIREASLPKCPPEDVPLFENIIGDIFPEVTVLKVNQLALEKVIYTATQQLG 1804
Query: 2235 LINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMT-------------D 2281
L N K K+IQ + +V G+M +GP+G GKTT L +A+T
Sbjct: 1805 LQNWSSQKEKIIQFYNQLQVCVGVMLVGPTGGGKTTVRRILEKALTLLPIADFLSVAERK 1864
Query: 2282 CGKPHREMR-------MNPKAITAPQMFGRLDVATNDWTDGIFSTLWRK----------- 2323
E + +NPK +T +++G+LD T +WTDG+ S R
Sbjct: 1865 SASKISERKGKVDICVLNPKCVTLSELYGQLDPNTMEWTDGLLSATIRSYVYFNTPKNTK 1924
Query: 2324 ---TLRAKKG-----------------------EHIWIILDGP----VDAIWI------- 2346
LR K E I ++ P D WI
Sbjct: 1925 KDIDLRLKSRISDLSNVFKLDSSDTTETDDNIFEEIEKVVKIPENHNFDWQWIILDGPVD 1984
Query: 2347 ----ENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSI 2402
ENLNSVLDD +TL LAN +RI + ++IFE N+ ASPATVSR MV+M
Sbjct: 1985 TFWVENLNSVLDDTRTLCLANSERIALTNKIRVIFEVDNLSQASPATVSRCAMVYMDPVD 2044
Query: 2403 LDWSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQN 2442
L W P ++ +L K S ++ ++S D F I+N
Sbjct: 2045 LGWEPYVKSWLLKTS--------KIISQSGVDCLEFMIKN 2076
Score = 120 bits (302), Expect = 2e-26
Identities = 77/255 (30%), Positives = 130/255 (50%), Gaps = 5/255 (1%)
Query: 2601 KGFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVN 2660
K + D + ++ ++NFS+ T + I + +R T G P ++ +FIDD+N
Sbjct: 2414 KKLLKNNDHKGVVVSTINFSTNVTAAKTKEMILKKLIRRTKDTLGAPKNNRILIFIDDMN 2473
Query: 2661 MPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRL 2720
MP+ + +G Q E++RQL++ G Y+ EK + +I D+ +AA + NDI RL
Sbjct: 2474 MPVSDMYGAQPPLELIRQLLDLGGVYDTEK-NTWKNIQDLSIVAACVPVV---NDISPRL 2529
Query: 2721 KRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIK 2780
+ FS+ PS+ + IF +G Y + F+ EV+ S +++ + ++ +
Sbjct: 2530 LKHFSMLVLPHPSQDILCTIFQA-HLGIYFSINNFTPEVQKSKDQIISCSLAIYHQVRQN 2588
Query: 2781 MLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIADRFTVSSDV 2840
MLPTP K HY+FNLRD+ ++ G+L V+ L+ HE RV DR +D
Sbjct: 2589 MLPTPTKCHYMFNLRDMFKLLLGLLQADRTVVNSKEMAALLFVHEATRVFHDRLIDFTDK 2648
Query: 2841 TWFDKALVSLVEEEF 2855
+ F + L +E F
Sbjct: 2649 SLFYRLLSRELENCF 2663
>gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sapiens]
Length = 798
Score = 445 bits (1144), Expect = e-124
Identities = 265/811 (32%), Positives = 433/811 (53%), Gaps = 30/811 (3%)
Query: 3830 ITEMRLVNEMYQTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYE 3889
+ ++ ++ MYQ SL+ F +F ++ R+ +R+AN+I+ +T+ VY+Y RGL+E
Sbjct: 1 MNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFE 60
Query: 3890 EHKFLFTLLLTLKIDIQRNRVKHEEFLTLIKGGASLDLKACPPKPSKWILDITWLNLVEL 3949
K + LT +I + V E L++ ++ P +++ W + L
Sbjct: 61 CDKLTYLAQLTFQILLMNREVNAVELDFLLRS----PVQTGTASPVEFLSHQAWGAVKVL 116
Query: 3950 SKLRQFSDVLDQISRNEKMWKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTI 4009
S + +FS++ I + K WK + + E PE+E LP + K+ +RL ++R+ PDR
Sbjct: 117 SSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEW-KNKTALQRLCMLRAMRPDRMT 175
Query: 4010 AQARKYIVDSMGEKYAEGVILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKI- 4068
R ++ + +G KY G LD ++EES P TP+ +LS G DP + + G++L
Sbjct: 176 YALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYT 235
Query: 4069 ----ETRYVSMGQGQEVHARKLLQQTMANGGWALLQNCHLGLDFMDELMDIIIE-TELVH 4123
VS+GQGQEV A L G W +LQN HL ++ L + E +E H
Sbjct: 236 FNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHSENSH 295
Query: 4124 DAFRLWMTTEAHKQ-----FPITLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSG 4178
FR++M+ E P +L+ SIK N+PP G+ A L + +QD L++ S
Sbjct: 296 PEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSR 355
Query: 4179 -SQWKPMLYAVAFLHSTVQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGV 4237
+++K +L+A+ + H+ V ERRKFG GWN Y FN D +V + N L+ V
Sbjct: 356 ETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLE---ANAKV 412
Query: 4238 SWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFGPDFSFYQGYNIPKCSTVDN 4297
+ +RY+ GEI YGG +TDD+D+RL T+ + M + S G+ +P +
Sbjct: 413 PYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPGFPLPGNMDYNG 472
Query: 4298 YLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVLDTILGIQPKDTSG--GGDETREAV 4355
Y QYI + +SP ++GLHPNA+I + ++ ++ + T+L +QP+D+ G TRE
Sbjct: 473 YHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEK 532
Query: 4356 VARLADDMLEKLPPDYVPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELK 4415
V L +++LE++ + F + E + K+ P + QE RM + ++ +L EL+
Sbjct: 533 VKALLEEILERVTDE---FNIPELMAKVEERTPYIVVAFQECGRMNILTREIQRSLRELE 589
Query: 4416 LAIDGTIIMSENLRDALDCMFDARIPAWWKKASWISST-LGFWFTELIERNSQFTSWVFN 4474
L + G + M+ ++ + + ++ +P W + ++ S+ L WF +L+ R + +W +
Sbjct: 590 LGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGD 649
Query: 4475 -GRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKWMKDDISAPPTEGV 4533
P W+TGFFNPQ FLTA+ Q R N+ W LD M L ++TK +++ +PP EG
Sbjct: 650 FTMPSTVWLTGFFNPQSFLTAIMQSTARKNE-WPLDQMALQCDMTKKNREEFRSPPREGA 708
Query: 4534 YVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIYAENNTLRDPR-FYSCPIYKKPVR 4592
Y++GL++EGA WD + + E+K K L MPV+ I A +D R YSCP+YK R
Sbjct: 709 YIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQR 768
Query: 4593 TDLNYIAAVDLRTAQTPEHWVLRGVALLCDV 4623
Y+ +L+T + P WVL GVALL +
Sbjct: 769 GP-TYVWTFNLKTKENPSKWVLAGVALLLQI 798
>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
Length = 4753
Score = 179 bits (454), Expect = 6e-44
Identities = 258/1268 (20%), Positives = 478/1268 (37%), Gaps = 178/1268 (14%)
Query: 1306 WEKLLARAGEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMASGLKPQEAS 1365
WE + L+S + + +L + L + L L+GP + Q ++
Sbjct: 912 WEAFQFEKSQASEFLLSKRHAIMPKLQQLMAAALAELEGL-LAKALSGPFMDPTQDQRST 970
Query: 1366 D-RLIMFQNQFDN-------IYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIYT 1417
+ +L+ + QF N ++ Y +T E LP +++ Q+I+
Sbjct: 971 EHQLVSLERQFQNTVSDLSELHHAYAIFTEDETPVPLPICGTRPIVQ-------QQRIWH 1023
Query: 1418 LYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLD-LKKIIDDF 1476
LY + E ++ + + +++ + + + ++ L+ L +I+ +F
Sbjct: 1024 LYRVISENISEWKCMAFAKFSPAMAQEKTEGWLTEAARMSTTLELHSPVLQHCMRILGEF 1083
Query: 1477 SECCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDICI 1536
PLL + S + + + G E L ++ PLL++ + I +
Sbjct: 1084 RSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQVWQ 1143
Query: 1537 SAVKERDIEQKLKQVINEWDNKTFTFGSF----------------------------KTR 1568
+ + ++ ++++ W+ + +F K
Sbjct: 1144 NENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVDKDS 1203
Query: 1569 GELLLRGDSTSEIIANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTV 1628
G +L S + ++++SL +L +L+ + +WV + ++E W+T
Sbjct: 1204 GTFIL--SDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLTF 1261
Query: 1629 QNLWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETL--- 1685
Q WI+L V I RF +D + +M + P V+ V
Sbjct: 1262 QQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSPY 1321
Query: 1686 --GQLLPHLLD----QLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQ 1739
GQ L LL +LE SL L FPR FF+SD L+ +L +S Q
Sbjct: 1322 FQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEAQ 1381
Query: 1740 AHLLNVFDNIKSVKFH-----EKIYD------------RILSISSQEGETIELDKPVMAE 1782
+ F ++ +V F EK D L++ GE ++L P+
Sbjct: 1382 LWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPLH 1441
Query: 1783 GNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLS------------------- 1823
++ WL SL + + +L +++ A G L E L
Sbjct: 1442 PDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWID 1501
Query: 1824 ---SFPAQVGLLGIQMIWTRDSEEALRNAKFDKKIMQKTNQAFLELLNTLIDVTT----- 1875
+FP Q L+ +++W + EEAL ++ M + LE+L +
Sbjct: 1502 LVQAFPWQCVLVAEEVVWRAEMEEAL--LEWGTLAMVSMHMRKLEVLVNFMRAQRASQGG 1559
Query: 1876 RDLSSTERVKY-ETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNE-------- 1926
+ L S + L+ + V RDI L + DF W++Q +++
Sbjct: 1560 QSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSP 1619
Query: 1927 --------DSDKMM------IHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGM 1972
S+ + I + +F+Y E+LG + + L +R + L AL
Sbjct: 1620 LQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLGPRLGPLPSLLPERPALVLLLALEE 1679
Query: 1973 SMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFD 2032
G GP G GK + + LG+ +V+ CS Q++ + L G Q G+W +
Sbjct: 1680 VACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLE 1739
Query: 2033 EFNRIDLPVLSVAAQQISII------LTCKKEHKKSFI-----------FTDGDNVTMNP 2075
+ +++ +LS Q++ + L + S I F + +V++
Sbjct: 1740 KVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRL 1799
Query: 2076 EFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKFF 2135
+G L + A +P NL + R VA+ +PD + + + L G D +A +
Sbjct: 1800 GYGCLLVLR---ALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLS 1856
Query: 2136 TLYKLCEEQLSKQVHYDFG-LRNIL-SVLRTLGAAKR----ANPMDTESTIVMRVLRDMN 2189
+ L E +S + L+ IL +RTL K P + +LR
Sbjct: 1857 KFFSLERELVSGPLPCRLPLLKQILEDTIRTLNVTKEEPKCQKPRSLAAIEEAALLRSPL 1916
Query: 2190 LSKLIDEDEPLFLSLIEDLFPN---ILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVI 2246
S L L+ LFP+ +L + Y ++ + ++++ GL P +
Sbjct: 1917 FSILNGLHLHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDILGSLE 1976
Query: 2247 QLFETQRVRHGMMTLGPSGAGKTTCIHTLMR------AMTDCG----KPHREMRMNPKAI 2296
QL + G++ LGP+G+GKTTC H+L + AM D +P + P +
Sbjct: 1977 QLSQALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGL 2036
Query: 2297 TAPQMFGRLDVATNDWTDGIFSTLWR-----------KTLRAKKGEHIWIILDGPVDAIW 2345
+ + G L+ + W GIF + R + G WII DG + W
Sbjct: 2037 SPQEFLGWLEGSC--WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAW 2094
Query: 2346 IENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDW 2405
++++ +L + L+L +G +I P ++ E + SP V +V+ W
Sbjct: 2095 LDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCGGE-QTW 2153
Query: 2406 SPILEGFL 2413
IL +
Sbjct: 2154 QCILSALM 2161
Score = 101 bits (252), Expect = 2e-20
Identities = 145/744 (19%), Positives = 302/744 (40%), Gaps = 114/744 (15%)
Query: 2937 HLVKISRVIRTPQGNALLV-GVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDL 2995
H+ ++ RV+ P+ + LL+ G G+G+ + LAS I F + S + +++ L
Sbjct: 2871 HVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLP---SGSEEAILQCL 2927
Query: 2996 KVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASV 3055
+ AG + + + D + L + + +SG + ++D I L
Sbjct: 2928 RDASWHAGMLSQPVALLVPSGV--DLTTLHRLLALATSGSFPGQYTEADLDRIGEHLPRE 2985
Query: 3056 ---MKKEFPRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALI-----S 3107
+K+ + E + F +V +LH+ F +G+K ++ L + +
Sbjct: 2986 NLGVKQNIKK-----EMVLQRFHQQVCSHLHL---FFLIGDKQAHKQLPSTLFLRLLQLA 3037
Query: 3108 GCTIDWFSRWPKDALVAVSEHFL---TSYDIDCSLEIKKEVVQCMGSFQDGVA---EKCV 3161
+ID + W + AL V++H L S +D ++ + S +A
Sbjct: 3038 TASIDRYEPWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAMALIHLSAT 3097
Query: 3162 DYFQRFRRSTH-VTPKSYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAAL 3220
Y + + VTPK++L F+ + + + ++++ A R+ LE L+ +
Sbjct: 3098 HYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLIKEHGTH 3157
Query: 3221 SKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIA 3280
+ + E++L+ + M +++ Q+ K ++++ + + + +++++++ +
Sbjct: 3158 ANLIFDLEQQLKDSGKSLSMFQQQL---EQSKLLYKQQLEECRHQ-ENLIENLARQRDAL 3213
Query: 3281 EEKLEAAKPALEEA-EAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKI 3339
+ + EA + +A L ++ +D +R+ PP ++R+ D + LF +
Sbjct: 3214 QAQREAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDAMCDLFHHET----- 3268
Query: 3340 DLEKSCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRV 3399
W + +L+ +F Q L FPK+ I + + L + P + + V
Sbjct: 3269 ---------GWASAKQLLCTEDFYQELVFFPKEKITDSELIKLHLILKAPGMDDAALRAV 3319
Query: 3400 CGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQENRHLLAMQDLQKAQAELDDKQAELD 3459
A L +W A+ + + LP +L+ LQ+ +A L +QA L
Sbjct: 3320 SRPAASLAAWLWAVLHYGLAHCRGLP--TDLL------------LQQVEATLTREQARLG 3365
Query: 3460 VVQAEYEQAMTEKQTL---LEDAERCRHKMQTASTLISGLAGEKER-------------W 3503
Q + ++ + L +EDA+ + + A TL G+ + W
Sbjct: 3366 YYQFQAQETLEHNLALAKMVEDAQASHNCV--AKTLSQAQCGQYHKWPMKAALLTPMRAW 3423
Query: 3504 TEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLNDW----------------- 3546
T Q Q+ + + GD LL +A + Y GPF R LL++W
Sbjct: 3424 TTQLQKLKGRCMTVFGDTLLCSAAIIYLGPFPPLRRQELLDEWLALCRGFQEALGPDDVA 3483
Query: 3547 ---RKEMKARKIPFGKN--------LNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVT 3595
+++ K+ IP KN ++ +L +W+ P + G+++
Sbjct: 3484 QALKRKQKSVSIP-PKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLR 3542
Query: 3596 -----KASRYPLLIDPQTQGKIWI 3614
+ R+PLL+DP + IW+
Sbjct: 3543 SPTHYSSCRWPLLLDPSNEALIWL 3566
Score = 68.6 bits (166), Expect = 1e-10
Identities = 86/402 (21%), Positives = 159/402 (39%), Gaps = 38/402 (9%)
Query: 2484 FVFALLWSAGAALELDGRRRLELWLRSRPTGTLELPPPAGPGDTAFDYYVAP-DGTWTHW 2542
F+FAL+W GA L + ++R + P P P FD +V+P DGT +
Sbjct: 2287 FLFALIWGFGAHLPSRFWPIFDTFIRDSISRLSNYPEPP-PSALVFDLHVSPEDGTLVPF 2345
Query: 2543 NTRTQEYLYPSDTTPEYGSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIKG 2602
T +YL S G+ P++ R +++ + G+ VLL GE T K+ ++
Sbjct: 2346 ---TGQYL-SSHIKGTLGTFH-PSIQTERLLYVVDLLLSGGQPVLLAGEAATGKSAFVEV 2400
Query: 2603 FMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNMP 2662
+ + P + FSS+ L+ R I+ + + + ++D+++
Sbjct: 2401 LVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLLFLLEDLHLA 2460
Query: 2663 IIN-EWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLK 2721
+ E Q E +RQ M+ + + + T + FLA + PG + RL
Sbjct: 2461 TSDPEKSCQPVLETLRQAMDGTVYAHSTLELQ-TLQPTVNFLATVTVPGYCERPLCPRLF 2519
Query: 2722 RQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKM 2781
R F++ ++A++ + I + + + E R LV + W+
Sbjct: 2520 RLFTVLALESMTQATLLERHVPI-IQAWLERFPSVERERALARGLVRASVEAWEAVCNCF 2578
Query: 2782 LPTPAKFHYVFNLRDLS----------------------------RVWQGMLNTTSEVIK 2813
+P+P HY F+L +S R G+ T V+
Sbjct: 2579 MPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCLTVMM 2638
Query: 2814 EPNDLLKLWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEF 2855
++++LW HE +R DR + ++ K L+ + + F
Sbjct: 2639 ATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVF 2680
Score = 58.2 bits (139), Expect = 2e-07
Identities = 122/643 (18%), Positives = 223/643 (34%), Gaps = 68/643 (10%)
Query: 3686 VLDGFRLYITTKLPNPAYTP----EISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEK 3741
V GF LY++T L A E+ +++D + M+ LE+Q+L ++ E ELE
Sbjct: 3716 VQPGFCLYLSTTLSLCAMEKVLGCELLKGLNVLDLGLNMEILEEQMLHEILCREYPELET 3775
Query: 3742 ERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEVTQKLEI 3801
L + ++ E+ LL L + + + + ++ E
Sbjct: 3776 RWQDLKIRALDTCKAVEAAEERLLTMLLFQNPKRQKPAKFLRNIVRAQGKLCQLRAHCEE 3835
Query: 3802 SAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSLARSVKS 3861
++Q YRPV G + +++++ + ++ S +L + +L
Sbjct: 3836 LEGQKLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVTKQALDSMKPR 3895
Query: 3862 PIT-----SKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEFL 3916
I + + + H+T ++ L L L L + + E L
Sbjct: 3896 EINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQATGKASELERL 3955
Query: 3917 TLIKGGASLDLKACPPKP------SKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWK 3970
L G A+ KP W+ W L L F + ++ + W+
Sbjct: 3956 ALWPGLAA-SPSTVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLCASLAGHSSAWQ 4014
Query: 3971 IWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVIL 4030
+ + P P + L ++L+L R P+ + +G E
Sbjct: 4015 AYLSLSSTVLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSLLGRPLDENTYA 4074
Query: 4031 DLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKIETRYVSMGQGQEVHAR------ 4084
++ S P++ LL P+ ++ L K+ +Y + +V A
Sbjct: 4075 P-TMPFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQLQVIALGSEAWD 4133
Query: 4085 ------KLLQQTMANGGWALLQNCHLGLDFMDELMDIIIE-------------------- 4118
L Q M G W +L NCHL + EL+ +++E
Sbjct: 4134 PVSVVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADLESEQLLDQP 4193
Query: 4119 ----TELVHDAFRLWM--TTEAHKQFPITLLQMSIK-FANDPPQGLRAGLKRTYS-GVSQ 4170
VH FRLW+ E+ P L Q S+ F N Q L G S ++Q
Sbjct: 4194 ESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWN---QSLELGHVLIDSVELAQ 4250
Query: 4171 DLLDVSSGSQWKPMLYAVAFLHSTVQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDD 4230
+L + +Q P+L LH + R+ +G ++Q +Q D
Sbjct: 4251 QVLYMQPPTQALPLL----LLHGLLLHRQLYGTRLQAHRGRWSQVTLTQVLQ----TQDQ 4302
Query: 4231 MDVKKGVSWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFS 4273
+ ++ + + YGG + D D+ L + + S
Sbjct: 4303 LWASLSNPRAAMQELAASVFYGGPLGDTEDREALISLTQACLS 4345
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 48.1 bits (113), Expect = 2e-04
Identities = 89/465 (19%), Positives = 182/465 (39%), Gaps = 77/465 (16%)
Query: 3093 EKFRNRALKFPALISGCTIDWF----SRWPKDALVAVSEHF------LTSYDIDCSLEIK 3142
EK +N+ L+ TI W +RW V + E F L ++ +D + +
Sbjct: 347 EKEKNKILRN-------TIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLT 399
Query: 3143 KE----VVQCMGSFQDGVAEKCVD-----YFQRFRRSTHVTPKSYL------------SF 3181
+ + +G+F D KC + Y Q + + +S L
Sbjct: 400 NDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEEL 459
Query: 3182 IQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMV 3241
+ + E+ L + E++KE +++ L+ + K +E++ + +++
Sbjct: 460 LASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELL 519
Query: 3242 LKEVTMKAQAAEKVKAEVQKVKD-------RAQAIVDSISKDKAIAEEKLEAAKPALEEA 3294
E+ K+ + AE+QK+K+ RA ++ S+ KD +AE + +++
Sbjct: 520 SDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKD--LAEIGIAVGNNDVKQP 577
Query: 3295 EAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEK----SCTMPSW 3350
E +A + + + C L + S K++ + +C +
Sbjct: 578 EGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRIS 637
Query: 3351 QESLKLMTAGNFLQNLQQFPK------DTINEEVIEFLS--PYFEMPDYN---IETAKRV 3399
Q K+ + +LQN++Q + D ++EE+++ + EM + ++TA V
Sbjct: 638 QHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEV 697
Query: 3400 CGNV-AGLCSWTKAMASFFSINKEVLPLKANLVV---QENRHLLAMQD--------LQKA 3447
V + S + S ++ + KA L+ +N+ ++ Q+ L+
Sbjct: 698 KQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKAT 757
Query: 3448 QAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTL 3492
E K EL V+Q EQA + + L E + ++QT L
Sbjct: 758 DQEKSRKLHELTVMQDRREQARQDLKGLEETVAK---ELQTLHNL 799
>gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
Length = 284
Score = 47.4 bits (111), Expect = 3e-04
Identities = 31/101 (30%), Positives = 55/101 (54%), Gaps = 10/101 (9%)
Query: 3211 KEASESVAALSKELEAKEKELQVANDKADMVLKEV-------TMKAQAAEKVKAEVQKVK 3263
K A + L +++ AKEK L+V+ D+ D VL+E+ +AA K +A+V +
Sbjct: 30 KAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLN 89
Query: 3264 DRAQAIVDSISKDK---AIAEEKLEAAKPALEEAEAALQTI 3301
R Q + + + + + A A +KLE A+ A +E+E ++ I
Sbjct: 90 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 130
Score = 34.7 bits (78), Expect = 2.3
Identities = 22/94 (23%), Positives = 50/94 (53%), Gaps = 4/94 (4%)
Query: 3208 EKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQ 3267
E +A VA+L++ ++ E+EL A ++ L+++ +AA++ + ++ ++ RAQ
Sbjct: 76 EAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQ 135
Query: 3268 AIVDSISKDKAIAEEKLEAAKPALEEAEAALQTI 3301
+ + I E +L+ AK E+A+ + +
Sbjct: 136 KDEEKME----IQEIQLKEAKHIAEDADRKYEEV 165
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 47.4 bits (111), Expect = 3e-04
Identities = 31/101 (30%), Positives = 55/101 (54%), Gaps = 10/101 (9%)
Query: 3211 KEASESVAALSKELEAKEKELQVANDKADMVLKEV-------TMKAQAAEKVKAEVQKVK 3263
K A + L +++ AKEK L+V+ D+ D VL+E+ +AA K +A+V +
Sbjct: 30 KAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLN 89
Query: 3264 DRAQAIVDSISKDK---AIAEEKLEAAKPALEEAEAALQTI 3301
R Q + + + + + A A +KLE A+ A +E+E ++ I
Sbjct: 90 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 130
Score = 34.7 bits (78), Expect = 2.3
Identities = 22/94 (23%), Positives = 50/94 (53%), Gaps = 4/94 (4%)
Query: 3208 EKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQ 3267
E +A VA+L++ ++ E+EL A ++ L+++ +AA++ + ++ ++ RAQ
Sbjct: 76 EAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQ 135
Query: 3268 AIVDSISKDKAIAEEKLEAAKPALEEAEAALQTI 3301
+ + I E +L+ AK E+A+ + +
Sbjct: 136 KDEEKME----IQEIQLKEAKHIAEDADRKYEEV 165
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 47.0 bits (110), Expect = 4e-04
Identities = 70/334 (20%), Positives = 134/334 (40%), Gaps = 48/334 (14%)
Query: 3207 LEKLKEASESV-AALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDR 3265
LEK E + V L +EL E + D + K+ T Q +EK+K + Q+++
Sbjct: 1935 LEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESH 1994
Query: 3266 AQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDC 3325
+ I +A +EK E LQT+ SD++ + L HL ++
Sbjct: 1995 QSECLHCIQVAEAEVKEKTEL-----------LQTLS-SDVSEL--LKDKTHLQEKLQS- 2039
Query: 3326 VLLLFQRKVSAVKIDLEKSCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSPY 3385
L + +S K +LE + ++ L + + + L + + +N
Sbjct: 2040 -LEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKA------ 2092
Query: 3386 FEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQENRHLLAMQDLQ 3445
+E A G A S T+ + + + L+ + E + L + L+
Sbjct: 2093 -------LEAALVEKGEFALRLSSTQE--EVHQLRRGIEKLRVRIEADEKKQLHIAEKLK 2143
Query: 3446 KAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLA-------- 3497
+ + E D + +++ ++ E + + ++ ++ DAE + +++T T I +A
Sbjct: 2144 ERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFEL 2203
Query: 3498 ------GEKERWTEQSQEFAAQTKRLVGDVLLAT 3525
EKE T+Q QE Q L D LL++
Sbjct: 2204 DLVTLRSEKENLTKQIQEKQGQLSEL--DKLLSS 2235
Score = 45.4 bits (106), Expect = 0.001
Identities = 134/681 (19%), Positives = 273/681 (40%), Gaps = 106/681 (15%)
Query: 3194 VEVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAE 3253
VE A R+++ E++ + + L +EA EK+ + AE
Sbjct: 2098 VEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKK-----------------QLHIAE 2140
Query: 3254 KVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLG 3313
K+K E ++ D + V+++ ++ ++EE E E ++A ++T++ R+L
Sbjct: 2141 KLK-ERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSL- 2198
Query: 3314 RPPHLIMRIMDCVLL-LFQRKVSAVKIDLEKSCTMPSWQESLKLMTAGNFLQNLQQFPKD 3372
++ + L+ L K + K EK + E KL+++ L ++ +
Sbjct: 2199 -------KVFELDLVTLRSEKENLTKQIQEKQGQL---SELDKLLSSFKSLLEEKEQAEI 2248
Query: 3373 TINEE---VIEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAM----ASFFSINKEVLP 3425
I EE +E L ++ + N E +CG+ + + +++ + +
Sbjct: 2249 QIKEESKTAVEMLQN--QLKELN-EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEK 2305
Query: 3426 LKANLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHK 3485
L+A L E + L +Q L++++ D + ++ ++ E E A T ++ +AE + +
Sbjct: 2306 LRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGE 2365
Query: 3486 MQTASTLISGLA--------------GEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYS 3531
++T I G+ EKE T + Q+ + +R+ ++ ++F +
Sbjct: 2366 VETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQK---EQERISELEIINSSFENIL 2422
Query: 3532 GPFNQEFRDL---------LLNDWRKEMKARKIPF--------GKNLNLSEMLIDAPTIS 3574
QE + +L KE+ R K NLS +
Sbjct: 2423 QEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEK 2482
Query: 3575 EWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNKES-----RNELQ-ITSL 3628
LQGL +N IV ++S L+ + + GK ++ K+ +N++Q L
Sbjct: 2483 AQLLQGLD----EAKNNYIVLQSSVNGLIQEVE-DGKQKLEKKDEEISRLKNQIQDQEQL 2537
Query: 3629 NHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTGSTFKV-----KVGDKE 3683
K + E L + L + ++ EL+ + VL+ T +V K + E
Sbjct: 2538 VSKLSQVEGEHQLWKEQNLELRNLTVELEQKI-QVLQSKNASLQDTLEVLQSSYKNLENE 2596
Query: 3684 VDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEKER 3743
+++ ++ K+ N E + + + L+++L G EK L E
Sbjct: 2597 LELTKMDKMSFVEKV-NKMTAKETELQREMHEMAQKTAELQEELSG-----EKNRLAGEL 2650
Query: 3744 THLMEDVTANKRRMKEL---EDNLLYRLTSTQGSLVEDESLI-VVLSNTKRTAEEVTQK- 3798
L+E++ ++K ++KEL L L VE E + ++ + E +K
Sbjct: 2651 QLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKH 2710
Query: 3799 ----LEISAETEVQINSAREE 3815
L+ + + EV+I + RE+
Sbjct: 2711 QALLLDTNKQYEVEIQTYREK 2731
Score = 39.3 bits (90), Expect = 0.092
Identities = 55/231 (23%), Positives = 108/231 (46%), Gaps = 34/231 (14%)
Query: 138 AITPDNIHQEVSFNMLDAADGGLLNSVRRLLSDIFIPALRATSHGWGELEGLQDAANIRQ 197
A+ +N EV L A G+ S+R L D+ +R+ E E L + Q
Sbjct: 2356 ALEAENSKGEVE--TLKAKIEGMTQSLRGLELDVV--TIRS------EKENLTNELQKEQ 2405
Query: 198 EFLSSLE----GFVNVLSGAQESLKEKVNLRKCDILELKTL----KEPTDYLTLANNPET 249
E +S LE F N+L QE +EKV +++ ++ L KE + + +N +
Sbjct: 2406 ERISELEIINSSFENIL---QEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQE 2462
Query: 250 LGKIED--------CMKVWIKQTEQVL--AENNQLLKEADDVGPRAELEHWKKRLSKFNY 299
K ++ C+++ Q Q L A+NN ++ ++ G E+E K++L K +
Sbjct: 2463 ACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDE 2522
Query: 300 LLEQLKS--PDVKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYL 348
+ +LK+ D + +++ L+ + + + W+E ++ + + T E + ++ L
Sbjct: 2523 EISRLKNQIQDQEQLVSKLSQVEGE-HQLWKEQNLELRNLTVELEQKIQVL 2572
Score = 36.2 bits (82), Expect = 0.78
Identities = 68/330 (20%), Positives = 133/330 (40%), Gaps = 20/330 (6%)
Query: 3195 EVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEK 3254
++R + M+ L + SE + ++ELE+ + E A+ +KE T Q
Sbjct: 1962 QLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSS 2021
Query: 3255 VKAEVQKVKDRAQAIVDSISKD-KAIAEEKLEAAKP----------ALEEAEAALQTIRP 3303
+E+ K K Q + S+ KD +A++ K E ++E+E+ +
Sbjct: 2022 DVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSE 2081
Query: 3304 SDIATVRTLGRPPHLIMRIMDCVLLL--FQRKVSAVKIDLEKSCTMPSWQESLKLMTAGN 3361
SD + ++ + L L Q +V ++ +EK E +L A
Sbjct: 2082 SDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEK 2141
Query: 3362 FLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINK 3421
+ ++ D++ ++V E L +M + N E N K + +
Sbjct: 2142 LKERERE--NDSLKDKV-ENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSL 2198
Query: 3422 EVLPLKANLVVQENRHLL-AMQDLQKAQAELDDKQAELDVVQAEYEQAMTE-KQTLLEDA 3479
+V L + E +L +Q+ Q +ELD + + E EQA + K+
Sbjct: 2199 KVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAV 2258
Query: 3480 ERCRHKMQTASTLISGLAGEKE--RWTEQS 3507
E +++++ + ++ L G++E + TEQS
Sbjct: 2259 EMLQNQLKELNEAVAALCGDQEIMKATEQS 2288
Score = 34.7 bits (78), Expect = 2.3
Identities = 59/307 (19%), Positives = 122/307 (39%), Gaps = 15/307 (4%)
Query: 3185 YKFIYGEKHVEVRTLANRMNTGLE----KLKEASESVAALSKELEAKEKELQVANDKADM 3240
++ I EK E + + +T +E +LKE +E VAAL + EA + + Q + + +
Sbjct: 2418 FENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVEC 2477
Query: 3241 VLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQT 3300
+ E Q ++ K ++ ++ + K E+K E + + Q
Sbjct: 2478 LELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQL 2537
Query: 3301 I-RPSDIATVRTLGRPPHLIMRIMDCVL----LLFQRKVSAVKIDLEKSCTMPSWQESLK 3355
+ + S + L + +L +R + L + Q K ++++ LE + E+
Sbjct: 2538 VSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENEL 2597
Query: 3356 LMTAGNFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMAS 3415
+T + + +++ K T E E EM E + + G L + +
Sbjct: 2598 ELTKMDKMSFVEKVNKMTAKE--TELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLE 2655
Query: 3416 FFSINKEVLPLKANLVVQENRHLLAMQDLQKAQAELDDK-QAELDVVQAEYEQAMTEKQT 3474
+K+ L L ++ + ++ + K Q E + K + E+ Q +A + Q
Sbjct: 2656 EIKSSKDQL---KELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQA 2712
Query: 3475 LLEDAER 3481
LL D +
Sbjct: 2713 LLLDTNK 2719
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 46.6 bits (109), Expect = 6e-04
Identities = 57/326 (17%), Positives = 128/326 (39%), Gaps = 40/326 (12%)
Query: 3195 EVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEK 3254
E+R + + +E L A S L + E + E ++ ++ L + + + +
Sbjct: 1272 ELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQT 1331
Query: 3255 VKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGR 3314
E+ ++ + + ++ +S+ KA+A + LE + LEE A +
Sbjct: 1332 ESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSAL------------- 1378
Query: 3315 PPHLIMRIM-DCVLLLFQRKVSA-VKIDLEK-----SCTMPSWQESLKLMTAGNFLQNLQ 3367
H + + DC LL Q + A + +L++ + + W+ + + +Q +
Sbjct: 1379 -AHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYE----ADAIQRTE 1433
Query: 3368 QFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLK 3427
+ EE + L+ + + +E A C ++ + + ++ E
Sbjct: 1434 EL------EEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSA 1487
Query: 3428 ANLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQ 3487
A + ++ RHL + L++++ + + +Q E E A E + L + R RH +
Sbjct: 1488 AAALDKKQRHL---------ERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHE 1538
Query: 3488 TASTLISGLAGEKERWTEQSQEFAAQ 3513
A + L E + E+ + Q
Sbjct: 1539 EALEALETLKRENKNLQEEISDLTDQ 1564
Score = 35.0 bits (79), Expect = 1.7
Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 12/100 (12%)
Query: 3199 LANRMNTGLEKLKEASES-VAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKA 3257
L + NTGL K+ E+ +A LS E+E +E + A +KA K +T A AE++K
Sbjct: 1764 LLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAK---KAITDAAMMAEELKK 1820
Query: 3258 EVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAA 3297
E Q + + K E+ + + LEEAE A
Sbjct: 1821 E--------QDTSAHLERMKKTLEQTVRELQARLEEAEQA 1852
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 46.2 bits (108), Expect = 8e-04
Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 11/101 (10%)
Query: 3208 EKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEK----VKAEVQKVK 3263
E+ K+ + +AA+ K+L+ E EL DK LK+ K + AEK +AEV +
Sbjct: 35 ERSKQLEDELAAMQKKLKGTEDEL----DKYSEALKDAQEKLELAEKKAADAEAEVASLN 90
Query: 3264 DRAQAIVDSISKDK---AIAEEKLEAAKPALEEAEAALQTI 3301
R Q + + + + + A A +KLE A+ A +E+E ++ I
Sbjct: 91 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 131
>gi|122937396 coiled-coil domain containing 150 [Homo sapiens]
Length = 1101
Score = 46.2 bits (108), Expect = 8e-04
Identities = 87/419 (20%), Positives = 172/419 (41%), Gaps = 64/419 (15%)
Query: 3141 IKKEVVQCMGSFQDGVAEK--CVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRT 3198
++ + + G + + EK ++ +RF+R + T K + + + V++ T
Sbjct: 449 LESTIARLRGELEASMQEKKSLLEEKERFQREVNKTEKEIVQERCNLEKELAKNKVDINT 508
Query: 3199 LANRMNTGLEKLKEASESVAALSKELEAKEKELQ-VANDKADMVLKEVTMKAQAAEKVKA 3257
L + + T E+ K ++ +A+L EL+ + +A K + + + A K++
Sbjct: 509 LTHNLQTLEEENKHLADQMASL--ELQQVTSDYHGLAQQKVEKITESKNKLAYENGKLQI 566
Query: 3258 EVQKVKDRAQAIVD-SISKDK------------AIAEEKLEAAKPALEEAEAALQTIRPS 3304
+V++++++ Q+ D S+ D A A +L A + L++A+A L+ ++
Sbjct: 567 KVKQLEEQVQSFTDTSLQNDHLRKMNKYLQTKYAQANSELSAKRVHLQQADAHLKEVKS- 625
Query: 3305 DIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLMTAGNFLQ 3364
L R + R + C + +K DLE E + GNF +
Sbjct: 626 ------ILERSKEELSRTVKCRNAALKES-QKLKEDLEAV-------EDRENKKVGNFQR 671
Query: 3365 NLQQFPKDTINEEVI--EFLSPYFEMPD----YNIETAKRVCGNVAGLCSWTKA-MASFF 3417
L + +D ++ L+ + +M IE +R +AGL
Sbjct: 672 QLAEAKEDNCKVTIMLENVLASHSKMQGALEKVQIELGRRD-SEIAGLKKERDLNQQRVQ 730
Query: 3418 SINKEVLPLKANLVVQENRHLLAMQDLQKAQ--AELDDK----------------QAELD 3459
+ EV +A ++V E++H ++ LQKA A D++ Q +LD
Sbjct: 731 KLEAEVDQWQARMLVMEDQHNSEIESLQKALGVAREDNRKLAMSLEQALQTNNHLQTKLD 790
Query: 3460 VVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLAGEK-ERWTEQSQEFAAQTKRL 3517
+Q + E E+Q L E + +M S + + L E+ E +Q Q TK++
Sbjct: 791 HIQEQLESKELERQNL----ETFKDRMTEESKVEAELHAERIEALRKQFQTERETTKKV 845
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 45.8 bits (107), Expect = 0.001
Identities = 136/687 (19%), Positives = 272/687 (39%), Gaps = 102/687 (14%)
Query: 3191 EKHVEVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQ 3250
EK + L T ++L++ + K A LQ A D++ ++ + +
Sbjct: 1293 EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETE 1352
Query: 3251 AAEKVKAEVQKVKDRAQAIV---------DSISKDKAIAEEKLEAAKPALEEAEAALQTI 3301
A KAE+Q+V +A + V D+I + + + E K + A+ L+EAE A++ +
Sbjct: 1353 A----KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQ-RLQEAEEAVEAV 1407
Query: 3302 RPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEK---SCTMPSWQESLKLMT 3358
+ +T R L I D ++ + + +A +D ++ + W++ K
Sbjct: 1408 NAKCSSLEKTKHR---LQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQ--KYEE 1462
Query: 3359 AGNFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAG--------LCSWT 3410
+ + L++ Q+ + +++ E+ + + Y E ++ +ET KR N+ L S
Sbjct: 1463 SQSELESSQKEAR-SLSTELFKLKNAYEESLEH-LETFKRENKNLQEEISDLTEQLGSSG 1520
Query: 3411 KAMASFFSINKEVLPLK-----------ANLVVQENRHLLAMQDLQKAQAELDDKQAELD 3459
K + + K++ K A+L +E + L A + + +AE++ K AE D
Sbjct: 1521 KTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 1580
Query: 3460 VVQAEYEQA-------MTEKQTLLEDAERCRHKMQTASTLISG--------------LAG 3498
E EQA + QT L+ R R++ + G +A
Sbjct: 1581 ---EEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAA 1637
Query: 3499 EKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLNDWRKEMKARKIPFG 3558
E ++ + Q T+ + D + A L + E R+ LL +E++A
Sbjct: 1638 EAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAI-VERRNNLLQAELEELRAVVEQTE 1696
Query: 3559 KNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNKE 3618
++ L+E + T L N L Q + S+ ++ Q +N E
Sbjct: 1697 RSRKLAEQEL-IETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQE---CRNAE 1752
Query: 3619 SRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALD-NVLERNFIKTGSTFKV 3677
+ + IT ++ E++ +E D + +++N +T +
Sbjct: 1753 EKAKKAITDA-----------------AMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH 1795
Query: 3678 KVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTEKQ 3737
++ + E L G + + KL E R + K + + G + + +
Sbjct: 1796 RLDEAEQIALKGGKKQLQ-KL-------EARVRELENELEAEQKRNAESVKG---MRKSE 1844
Query: 3738 ELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVE-DESLIVVLSNTKRTAEEVT 3796
KE T+ E+ N R+++L D L ++ + + E +E LS ++ E+
Sbjct: 1845 RRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELD 1904
Query: 3797 QKLEISAETEVQINSAREEYRPVATRG 3823
+ E + E Q+N R + R + T+G
Sbjct: 1905 EAEERADIAESQVNKLRAKSRDIGTKG 1931
Score = 43.5 bits (101), Expect = 0.005
Identities = 101/508 (19%), Positives = 199/508 (39%), Gaps = 57/508 (11%)
Query: 684 QIEEIHVGLEASLLVKAPGTGELFVNFDPQILILFRETECMAQMGLEVSP-----LATSL 738
+IE++ V +E S A + NFD +IL +++ +Q LE S L+T L
Sbjct: 1424 EIEDLMVDVERSNAAAA-ALDKKQRNFD-KILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 739 FQKRDRYKRNFSNMKMMLAEYQRVKSKIPAAIEQL-----IVPHLAKVDEALQPGLAALT 793
F+ ++ Y+ + +++ E + ++ +I EQL + L KV + L+ L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 794 WTSLNIEAYLENTFAKIKDLELLLDRVNDLIEFRIDAILEEMSSTPLCQLPQEEPLTCEE 853
EA LE+ KI +L +++ IE ++ EEM + L +
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQA------KRNHLRVVD 1595
Query: 854 FLQMTKDLCVNGAQILHFKSSLVEEAVNELVNMLLDVEVLSEEESEKISNENSVNYKNE- 912
LQ + D +E +NE+ L ++ E +++ + S+ +
Sbjct: 1596 SLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQI 1655
Query: 913 --SSAKREEGNFDTLTSSINARANALLL-----------TTVTRKKKETEMLGEEARELL 959
A R + + + R N L T +RK E E++ R L
Sbjct: 1656 QLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQL 1715
Query: 960 SHFNH-------QNMDALLKVTRNTLEAIRKRIHSSHTINFRDSNSASNMKQNSLPIFRA 1012
H + + MDA L + +E + ++ + A+ M +
Sbjct: 1716 LHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDT 1775
Query: 1013 SVTLAIPNIVMAPALEDVQQTLNKAVECIISVPKGVRQWSSELLSKKKIQERKMAALQS- 1071
S L M ++D+Q L++A + + KG ++ +L ++ + E ++ A Q
Sbjct: 1776 SAHLERMKKNMEQTIKDLQHRLDEAEQIAL---KGGKKQLQKLEARVRELENELEAEQKR 1832
Query: 1072 NEDSDSDVEMGENELQDTLEIASVNLPIPVQTKNYYKNVSENKEIV-KL---VSVLSTII 1127
N +S + E +++ + QT+ KN+ +++V KL V
Sbjct: 1833 NAESVKGMRKSERRIKE----------LTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQA 1882
Query: 1128 NSTKKEVITSMDCFKRYNHIWQKGKEEA 1155
+++ T++ F++ H + +E A
Sbjct: 1883 EEAEEQANTNLSKFRKVQHELDEAEERA 1910
>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
[Homo sapiens]
Length = 8749
Score = 45.4 bits (106), Expect = 0.001
Identities = 162/834 (19%), Positives = 302/834 (36%), Gaps = 147/834 (17%)
Query: 625 GKILWARQLFHRIQQPMQLFQQ-HPAVLSTAE-----------AKPIIRSYNRMAKVLLE 672
GKI + R Q LF+Q H +L+ E ++ + ++ VL
Sbjct: 839 GKINEIITVLEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKFVTLSNVLKH 898
Query: 673 FEVLFHRAWLRQIEEIHVGLEASLLVKAPGTGELFVNFDPQILILFRETEC-------MA 725
F+ RQI +IHV ++ +VK G + V + +++ F E+ +A
Sbjct: 899 FD---QTRLQRQIADIHVAFQS--MVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIA 953
Query: 726 QMGLEVSPLATSLFQKRDRYKRNFSN--MKMMLAEYQRVKSKIPAAIEQLIVPHLAKVDE 783
Q GLE L ++ + + L + +P +Q + + K+ +
Sbjct: 954 QEGLEEKGDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHK 1013
Query: 784 ALQP--GLAALTWTSLNIEAYLENTFAKIKDLELLLDRVNDLI-EFRIDAILEEMSSTPL 840
+ G A L I+ A +++ LDR L+ + + I++E
Sbjct: 1014 QWKDLQGEAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMPQEGSEKIIKEHRVFFS 1073
Query: 841 CQLPQEEPLTCEEFLQMTKDLCV---------NGAQILHFKSSLVEEAVNELVNMLLDVE 891
+ P CE+ LQ+ ++LCV + H + A++ L++
Sbjct: 1074 DKGPHH---LCEKRLQLIEELCVKLPVRDPVRDTPGTCHVTLKELRAAIDSTYRKLMEDP 1130
Query: 892 VLSEEESEKISNENSVNYKNESSAKREEGN-FDTLTSSINARANALLLTTVTRKKKETEM 950
++ + + S +S NE+ K +G DT RA + VT++ +
Sbjct: 1131 DKWKDYTSRFSEFSSWISTNETQLKGIKGEAIDTANHGEVKRAVEEIRNGVTKRGETLSW 1190
Query: 951 LGEEAR---ELLSHFNHQNMDALLKVTRNTLEAIRKRIHSSHTI--NFRDSNSASNMKQN 1005
L + E+ S Q L ++ +A+ + + NF D + +N
Sbjct: 1191 LKSRLKVLTEVSSENEAQKQGDELAKLSSSFKALVTLLSEVEKMLSNFGDCVQYKEIVKN 1250
Query: 1006 SLPIF---------RASVTLAIPNIVMAPAL---------------EDVQQTLNKAVECI 1041
SL +A L N+ A L DVQQ + +A +
Sbjct: 1251 SLEELISGSKEVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQGE 1310
Query: 1042 ISVP----KGVRQWSSELLSKKKIQERKMAALQ----------SNED------------- 1074
+P + +R+ S L ++ +ER+ +Q +N++
Sbjct: 1311 GGLPDRGHEELRKLESTLDGLERSRERQERRIQVTLRKWERFETNKETVVRYLFQTGSSH 1370
Query: 1075 ----SDSDVEMGENELQDTLEIASVNLPIPVQTKNYYKNVSE------NKEIV----KLV 1120
S S +E +EL+ T E + I VQ +N K SE NK+++ K +
Sbjct: 1371 ERFLSFSSLESLSSELEQTKEFSKRTESIAVQAENLVKEASEIPLGPQNKQLLQQQAKSI 1430
Query: 1121 SVLSTIINSTKKEVITSMDCFK-RYNH---------IWQKGKEEAIKTFITQSPLLS--- 1167
+ T +E I +M+ K +++H +W KE+ + T S +
Sbjct: 1431 KEQVKKLEDTLEEDIKTMEMVKTKWDHFGSNFETLSVWITEKEKELNALETSSSAMDMQI 1490
Query: 1168 --------EFESQILYFQNLEQEINAEPEYVCVGSIALYTADLKFA------LTAETKAW 1213
E ES++ LE+E + ++V G A A L L +
Sbjct: 1491 SQIKVTIQEIESKLSSIVGLEEEAQSFAQFVTTGESARIKAKLTQIRRYGEELREHAQCL 1550
Query: 1214 MVVIGRHCNK--KYRSEMENIFMLIEEFNKKLNRPIKDLDDIRIAMAALKEIREEQISID 1271
I H ++ K+ + I + EF KL PIK I + ++ +E + +
Sbjct: 1551 EGTILGHLSQQQKFEENLRKIQQSVSEFEDKLAVPIK----ICSSATETYKVLQEHMDLC 1606
Query: 1272 FQVGPIEESYALLNRYGLLIAREE--IDKVDTLHYAWEKLLARAGEVQNKLVSL 1323
+ + + + + + + + L +E +L RA E Q L +L
Sbjct: 1607 QALESLSSAITAFSASARKVVNRDSCVQEAAALQQQYEDILRRAKERQTALENL 1660
Score = 36.6 bits (83), Expect = 0.60
Identities = 56/307 (18%), Positives = 124/307 (40%), Gaps = 36/307 (11%)
Query: 3220 LSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKV-KD------RAQAIVDS 3272
LS +L +L++ + D + KEV ++++ ++QK+ KD + +A D+
Sbjct: 5325 LSLQLAEVALDLKIRDQIQDKI-KEVEQSKATSQELSRQIQKLAKDLTTILTKLKAKTDN 5383
Query: 3273 ISK---DKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLL 3329
+ + D+ + E+L+ L E +AA+Q + + L + + + +
Sbjct: 5384 VVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQ 5443
Query: 3330 FQRKVSAVKIDLEKSCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSPYFEMP 3389
+ ++S + + + + + E L+L+ +++ + TI L + +
Sbjct: 5444 AENRLSKLN---QAASHLEEYNEMLELIL--KWIEKAKVLAHGTIAWNSASQLREQYILH 5498
Query: 3390 DYNIETAKRVCGNVAGLCSWTKAMASFFSINK---EVLPLKANLVVQENRHLLAMQDLQK 3446
+E +K + + + + + S + K +V L + +Q+LQ
Sbjct: 5499 QTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQD 5558
Query: 3447 AQAELDDKQAELDVVQAEYEQA-----------------MTEKQTLLEDAERCRHKMQTA 3489
A ++ +AEL +QA EQA ++ +Q LL + E + K+Q
Sbjct: 5559 AAKDMKKFEAELKKLQAALEQAQATLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVQAV 5618
Query: 3490 STLISGL 3496
S L
Sbjct: 5619 QLCQSAL 5625
>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
[Homo sapiens]
Length = 8797
Score = 45.4 bits (106), Expect = 0.001
Identities = 162/834 (19%), Positives = 302/834 (36%), Gaps = 147/834 (17%)
Query: 625 GKILWARQLFHRIQQPMQLFQQ-HPAVLSTAE-----------AKPIIRSYNRMAKVLLE 672
GKI + R Q LF+Q H +L+ E ++ + ++ VL
Sbjct: 832 GKINEIITVLEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKFVTLSNVLKH 891
Query: 673 FEVLFHRAWLRQIEEIHVGLEASLLVKAPGTGELFVNFDPQILILFRETEC-------MA 725
F+ RQI +IHV ++ +VK G + V + +++ F E+ +A
Sbjct: 892 FD---QTRLQRQIADIHVAFQS--MVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIA 946
Query: 726 QMGLEVSPLATSLFQKRDRYKRNFSN--MKMMLAEYQRVKSKIPAAIEQLIVPHLAKVDE 783
Q GLE L ++ + + L + +P +Q + + K+ +
Sbjct: 947 QEGLEEKGDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHK 1006
Query: 784 ALQP--GLAALTWTSLNIEAYLENTFAKIKDLELLLDRVNDLI-EFRIDAILEEMSSTPL 840
+ G A L I+ A +++ LDR L+ + + I++E
Sbjct: 1007 QWKDLQGEAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMPQEGSEKIIKEHRVFFS 1066
Query: 841 CQLPQEEPLTCEEFLQMTKDLCV---------NGAQILHFKSSLVEEAVNELVNMLLDVE 891
+ P CE+ LQ+ ++LCV + H + A++ L++
Sbjct: 1067 DKGPHH---LCEKRLQLIEELCVKLPVRDPVRDTPGTCHVTLKELRAAIDSTYRKLMEDP 1123
Query: 892 VLSEEESEKISNENSVNYKNESSAKREEGN-FDTLTSSINARANALLLTTVTRKKKETEM 950
++ + + S +S NE+ K +G DT RA + VT++ +
Sbjct: 1124 DKWKDYTSRFSEFSSWISTNETQLKGIKGEAIDTANHGEVKRAVEEIRNGVTKRGETLSW 1183
Query: 951 LGEEAR---ELLSHFNHQNMDALLKVTRNTLEAIRKRIHSSHTI--NFRDSNSASNMKQN 1005
L + E+ S Q L ++ +A+ + + NF D + +N
Sbjct: 1184 LKSRLKVLTEVSSENEAQKQGDELAKLSSSFKALVTLLSEVEKMLSNFGDCVQYKEIVKN 1243
Query: 1006 SLPIF---------RASVTLAIPNIVMAPAL---------------EDVQQTLNKAVECI 1041
SL +A L N+ A L DVQQ + +A +
Sbjct: 1244 SLEELISGSKEVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQGE 1303
Query: 1042 ISVP----KGVRQWSSELLSKKKIQERKMAALQ----------SNED------------- 1074
+P + +R+ S L ++ +ER+ +Q +N++
Sbjct: 1304 GGLPDRGHEELRKLESTLDGLERSRERQERRIQVTLRKWERFETNKETVVRYLFQTGSSH 1363
Query: 1075 ----SDSDVEMGENELQDTLEIASVNLPIPVQTKNYYKNVSE------NKEIV----KLV 1120
S S +E +EL+ T E + I VQ +N K SE NK+++ K +
Sbjct: 1364 ERFLSFSSLESLSSELEQTKEFSKRTESIAVQAENLVKEASEIPLGPQNKQLLQQQAKSI 1423
Query: 1121 SVLSTIINSTKKEVITSMDCFK-RYNH---------IWQKGKEEAIKTFITQSPLLS--- 1167
+ T +E I +M+ K +++H +W KE+ + T S +
Sbjct: 1424 KEQVKKLEDTLEEDIKTMEMVKTKWDHFGSNFETLSVWITEKEKELNALETSSSAMDMQI 1483
Query: 1168 --------EFESQILYFQNLEQEINAEPEYVCVGSIALYTADLKFA------LTAETKAW 1213
E ES++ LE+E + ++V G A A L L +
Sbjct: 1484 SQIKVTIQEIESKLSSIVGLEEEAQSFAQFVTTGESARIKAKLTQIRRYGEELREHAQCL 1543
Query: 1214 MVVIGRHCNK--KYRSEMENIFMLIEEFNKKLNRPIKDLDDIRIAMAALKEIREEQISID 1271
I H ++ K+ + I + EF KL PIK I + ++ +E + +
Sbjct: 1544 EGTILGHLSQQQKFEENLRKIQQSVSEFEDKLAVPIK----ICSSATETYKVLQEHMDLC 1599
Query: 1272 FQVGPIEESYALLNRYGLLIAREE--IDKVDTLHYAWEKLLARAGEVQNKLVSL 1323
+ + + + + + + + L +E +L RA E Q L +L
Sbjct: 1600 QALESLSSAITAFSASARKVVNRDSCVQEAAALQQQYEDILRRAKERQTALENL 1653
Score = 36.6 bits (83), Expect = 0.60
Identities = 56/307 (18%), Positives = 124/307 (40%), Gaps = 36/307 (11%)
Query: 3220 LSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKV-KD------RAQAIVDS 3272
LS +L +L++ + D + KEV ++++ ++QK+ KD + +A D+
Sbjct: 5396 LSLQLAEVALDLKIRDQIQDKI-KEVEQSKATSQELSRQIQKLAKDLTTILTKLKAKTDN 5454
Query: 3273 ISK---DKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLL 3329
+ + D+ + E+L+ L E +AA+Q + + L + + + +
Sbjct: 5455 VVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQ 5514
Query: 3330 FQRKVSAVKIDLEKSCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSPYFEMP 3389
+ ++S + + + + + E L+L+ +++ + TI L + +
Sbjct: 5515 AENRLSKLN---QAASHLEEYNEMLELIL--KWIEKAKVLAHGTIAWNSASQLREQYILH 5569
Query: 3390 DYNIETAKRVCGNVAGLCSWTKAMASFFSINK---EVLPLKANLVVQENRHLLAMQDLQK 3446
+E +K + + + + + S + K +V L + +Q+LQ
Sbjct: 5570 QTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQD 5629
Query: 3447 AQAELDDKQAELDVVQAEYEQA-----------------MTEKQTLLEDAERCRHKMQTA 3489
A ++ +AEL +QA EQA ++ +Q LL + E + K+Q
Sbjct: 5630 AAKDMKKFEAELKKLQAALEQAQATLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVQAV 5689
Query: 3490 STLISGL 3496
S L
Sbjct: 5690 QLCQSAL 5696
>gi|93102364 SWAP-70 protein [Homo sapiens]
Length = 585
Score = 45.1 bits (105), Expect = 0.002
Identities = 45/201 (22%), Positives = 82/201 (40%), Gaps = 16/201 (7%)
Query: 3112 DWFSRWPKDALVAVSEHFLTSYDIDCSLEIKKEVVQ-----CMGSFQDGVAEKCVDYFQR 3166
+W RW V + + SY + L+ KK + C+ S D +KC+ +
Sbjct: 226 NWTERW------FVLKPNIISYYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLVKC 279
Query: 3167 FRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELEA 3226
F ++ ++ + + I+ H+ ++ KE + A +ELE
Sbjct: 280 FDKTFEISASDKKKKQEWIQAIHSTIHLLKLGSPPPHKEARQRRKELRKKQLAEQEELER 339
Query: 3227 KEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDS-----ISKDKAIAE 3281
+ KELQ AN+ L+ V K + A AE +K + + Q + + + ++K I +
Sbjct: 340 QMKELQAANESKQQELEAVRKKLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQ 399
Query: 3282 EKLEAAKPALEEAEAALQTIR 3302
+ E E E LQ +R
Sbjct: 400 QMEEQVAQKSSELEQYLQRVR 420
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 162,983,535
Number of Sequences: 37866
Number of extensions: 7129388
Number of successful extensions: 24393
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 221
Number of HSP's that attempted gapping in prelim test: 21119
Number of HSP's gapped (non-prelim): 2970
length of query: 4624
length of database: 18,247,518
effective HSP length: 123
effective length of query: 4501
effective length of database: 13,590,000
effective search space: 61168590000
effective search space used: 61168590000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.