BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|189083832 inhibitor of growth family, member 4 isoform 6 [Homo sapiens] (179 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|189083832 inhibitor of growth family, member 4 isoform 6 [Hom... 350 4e-97 gi|189083821 inhibitor of growth family, member 4 isoform 9 [Hom... 327 3e-90 gi|38201670 inhibitor of growth family, member 4 isoform 1 [Homo... 318 1e-87 gi|189083826 inhibitor of growth family, member 4 isoform 3 [Hom... 314 2e-86 gi|189083828 inhibitor of growth family, member 4 isoform 4 [Hom... 313 4e-86 gi|189083830 inhibitor of growth family, member 4 isoform 5 [Hom... 265 2e-71 gi|18644730 inhibitor of growth family, member 5 [Homo sapiens] 215 2e-56 gi|38201667 inhibitor of growth family, member 1 isoform A [Homo... 87 6e-18 gi|38201655 inhibitor of growth family, member 3 isoform 1 [Homo... 85 4e-17 gi|4504695 inhibitor of growth family, member 2 [Homo sapiens] 73 1e-13 gi|38201659 inhibitor of growth family, member 3 isoform 3 [Homo... 60 8e-10 gi|38201663 inhibitor of growth family, member 1 isoform C [Homo... 47 1e-05 gi|38201661 inhibitor of growth family, member 1 isoform D [Homo... 47 1e-05 gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 47 1e-05 gi|38201665 inhibitor of growth family, member 1 isoform B [Homo... 43 2e-04 gi|35493853 otoferlin isoform c [Homo sapiens] 41 5e-04 gi|35493868 otoferlin isoform b [Homo sapiens] 41 5e-04 gi|35493860 otoferlin isoform d [Homo sapiens] 41 5e-04 gi|34740331 otoferlin isoform a [Homo sapiens] 41 5e-04 gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 39 0.003 gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 38 0.004 gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 38 0.004 gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 38 0.005 gi|55770834 centromere protein F [Homo sapiens] 38 0.005 gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 37 0.009 gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 37 0.009 gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 37 0.009 gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 37 0.009 gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 37 0.012 gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 37 0.012 >gi|189083832 inhibitor of growth family, member 4 isoform 6 [Homo sapiens] Length = 179 Score = 350 bits (898), Expect = 4e-97 Identities = 179/179 (100%), Positives = 179/179 (100%) Query: 1 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE Sbjct: 1 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60 Query: 61 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD Sbjct: 61 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120 Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSGSILPVWG 179 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSGSILPVWG Sbjct: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSGSILPVWG 179 >gi|189083821 inhibitor of growth family, member 4 isoform 9 [Homo sapiens] Length = 249 Score = 327 bits (839), Expect = 3e-90 Identities = 169/172 (98%), Positives = 169/172 (98%) Query: 1 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE Sbjct: 1 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60 Query: 61 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD Sbjct: 61 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120 Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSG 172 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRT P G Sbjct: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYG 172 >gi|38201670 inhibitor of growth family, member 4 isoform 1 [Homo sapiens] Length = 248 Score = 318 bits (816), Expect = 1e-87 Identities = 167/172 (97%), Positives = 167/172 (97%), Gaps = 1/172 (0%) Query: 1 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE Sbjct: 1 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60 Query: 61 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD Sbjct: 61 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120 Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSG 172 YDSSSSKG KK RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRT P G Sbjct: 121 YDSSSSKG-KKSRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYG 171 >gi|189083826 inhibitor of growth family, member 4 isoform 3 [Homo sapiens] Length = 246 Score = 314 bits (805), Expect = 2e-86 Identities = 165/172 (95%), Positives = 166/172 (96%), Gaps = 3/172 (1%) Query: 1 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE Sbjct: 1 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60 Query: 61 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD Sbjct: 61 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120 Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSG 172 YDSSSS K+GRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRT P G Sbjct: 121 YDSSSS---KEGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYG 169 >gi|189083828 inhibitor of growth family, member 4 isoform 4 [Homo sapiens] Length = 245 Score = 313 bits (803), Expect = 4e-86 Identities = 165/172 (95%), Positives = 165/172 (95%), Gaps = 4/172 (2%) Query: 1 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE Sbjct: 1 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60 Query: 61 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD Sbjct: 61 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120 Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSG 172 YDSSSS KGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRT P G Sbjct: 121 YDSSSS----KGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYG 168 >gi|189083830 inhibitor of growth family, member 4 isoform 5 [Homo sapiens] Length = 225 Score = 265 bits (677), Expect = 2e-71 Identities = 144/172 (83%), Positives = 145/172 (84%), Gaps = 24/172 (13%) Query: 1 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60 MAAGMYLEHYLD+ LKAEIDKLATEYMSSARSLSSEE Sbjct: 1 MAAGMYLEHYLDN------------------------LKAEIDKLATEYMSSARSLSSEE 36 Query: 61 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD Sbjct: 37 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 96 Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSG 172 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRT P G Sbjct: 97 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYG 148 >gi|18644730 inhibitor of growth family, member 5 [Homo sapiens] Length = 240 Score = 215 bits (547), Expect = 2e-56 Identities = 108/161 (67%), Positives = 132/161 (81%), Gaps = 2/161 (1%) Query: 1 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60 MA MYLEHYLDSIENLP ELQRNFQLMR+LDQRTED KAEID LA EY+S+ ++LS ++ Sbjct: 1 MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQ 60 Query: 61 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120 ++ L++IQ AY KCKE+ DDKVQLAMQTYEMVDKHIRRLD DLARFEADLK+K +E SD Sbjct: 61 RVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MEGSD 119 Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKK 161 ++SS +G KKGR QKEK+ +R R + + S+E+ PK + K Sbjct: 120 FESSGGRGLKKGRGQKEKRGSRGRGR-RTSEEDTPKKKKHK 159 >gi|38201667 inhibitor of growth family, member 1 isoform A [Homo sapiens] Length = 279 Score = 87.4 bits (215), Expect = 6e-18 Identities = 47/149 (31%), Positives = 84/149 (56%), Gaps = 4/149 (2%) Query: 6 YLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALL 65 Y+E YLDSIE+LPF+LQRN LMR++D + +++ E+D+ Y +R +K +L Sbjct: 15 YVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDEC---YERFSRETDGAQKRRML 71 Query: 66 KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSS 125 +Q A + +E GD+K+Q+ Q E+V+ R++D+ + FEA + + + + Sbjct: 72 HCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGA 131 Query: 126 SKGKKKGRTQKEK-KAARARSKGKNSDEE 153 + K + Q +K + R+R + N + E Sbjct: 132 DRPKGEAAAQADKPNSKRSRRQRNNENRE 160 >gi|38201655 inhibitor of growth family, member 3 isoform 1 [Homo sapiens] Length = 418 Score = 84.7 bits (208), Expect = 4e-17 Identities = 39/108 (36%), Positives = 71/108 (65%) Query: 5 MYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLAL 64 +YLE YL+ IE LP +L+ F MR++D + ++ ++++ +E+ +A+ E + Sbjct: 2 LYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREEQ 61 Query: 65 LKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLK 112 + I++ Y K E D+KVQLA Q Y++VD+H+R+LD +LA+F+ +L+ Sbjct: 62 MASIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELE 109 >gi|4504695 inhibitor of growth family, member 2 [Homo sapiens] Length = 280 Score = 72.8 bits (177), Expect = 1e-13 Identities = 42/161 (26%), Positives = 86/161 (53%), Gaps = 8/161 (4%) Query: 6 YLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALL 65 Y++ YL+ +E+LP ++QRN ++R+LD + ++ EID + +Y + +K L Sbjct: 27 YVQDYLECVESLPHDMQRNVSVLRELDNKYQETLKEIDDVYEKY---KKEDDLNQKKRLQ 83 Query: 66 KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLK-EKQIESSDYDSS 124 + +Q A +E GD+K+Q+ Q E+V+ R+++ F+ + E+ + + DSS Sbjct: 84 QLLQRALINSQELGDEKIQIVTQMLELVENRARQMELHSQCFQDPAESERASDKAKMDSS 143 Query: 125 ----SSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKK 161 SS+ ++ RT + + + ++ D++ PK + K Sbjct: 144 QPERSSRRPRRQRTSESRDLCHMANGIEDCDDQPPKEKKSK 184 >gi|38201659 inhibitor of growth family, member 3 isoform 3 [Homo sapiens] Length = 92 Score = 60.5 bits (145), Expect = 8e-10 Identities = 29/88 (32%), Positives = 53/88 (60%) Query: 5 MYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLAL 64 +YLE YL+ IE LP +L+ F MR++D + ++ ++++ +E+ +A+ E + Sbjct: 2 LYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREEQ 61 Query: 65 LKQIQEAYGKCKEFGDDKVQLAMQTYEM 92 + I++ Y K E D+KVQLA Q Y++ Sbjct: 62 MASIKKDYYKALEDADEKVQLANQIYDL 89 >gi|38201663 inhibitor of growth family, member 1 isoform C [Homo sapiens] Length = 235 Score = 46.6 bits (109), Expect = 1e-05 Identities = 26/106 (24%), Positives = 52/106 (49%), Gaps = 1/106 (0%) Query: 49 YMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFE 108 Y +R +K +L +Q A + +E GD+K+Q+ Q E+V+ R++D+ + FE Sbjct: 11 YERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFE 70 Query: 109 ADLKEKQIESSDYDSSSSKGKKKGRTQKEK-KAARARSKGKNSDEE 153 A + + + + + K + Q +K + R+R + N + E Sbjct: 71 AQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRE 116 >gi|38201661 inhibitor of growth family, member 1 isoform D [Homo sapiens] Length = 422 Score = 46.6 bits (109), Expect = 1e-05 Identities = 26/106 (24%), Positives = 52/106 (49%), Gaps = 1/106 (0%) Query: 49 YMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFE 108 Y +R +K +L +Q A + +E GD+K+Q+ Q E+V+ R++D+ + FE Sbjct: 198 YERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFE 257 Query: 109 ADLKEKQIESSDYDSSSSKGKKKGRTQKEK-KAARARSKGKNSDEE 153 A + + + + + K + Q +K + R+R + N + E Sbjct: 258 AQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRE 303 >gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo sapiens] Length = 1940 Score = 46.6 bits (109), Expect = 1e-05 Identities = 44/168 (26%), Positives = 78/168 (46%), Gaps = 13/168 (7%) Query: 1 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60 M A + +H DS+ L ++ ++ + L++ + K EID L++ S ++S ++ E Sbjct: 1189 MVAALRKKH-ADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLE 1247 Query: 61 KL--ALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIES 118 K+ L Q+ EA GK +E +L Q RL T+ L+EK ES Sbjct: 1248 KICRTLEDQLSEARGKNEEIQRSLSELTTQK--------SRLQTEAGELSRQLEEK--ES 1297 Query: 119 SDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVR 166 S SK +T++ K+ +K KN+ A ++++ L+R Sbjct: 1298 IVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLR 1345 >gi|38201665 inhibitor of growth family, member 1 isoform B [Homo sapiens] Length = 210 Score = 42.7 bits (99), Expect = 2e-04 Identities = 23/91 (25%), Positives = 47/91 (51%), Gaps = 1/91 (1%) Query: 64 LLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDS 123 +L +Q A + +E GD+K+Q+ Q E+V+ R++D+ + FEA + + + Sbjct: 1 MLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKA 60 Query: 124 SSSKGKKKGRTQKEK-KAARARSKGKNSDEE 153 + + K + Q +K + R+R + N + E Sbjct: 61 GADRPKGEAAAQADKPNSKRSRRQRNNENRE 91 >gi|35493853 otoferlin isoform c [Homo sapiens] Length = 1307 Score = 41.2 bits (95), Expect = 5e-04 Identities = 20/61 (32%), Positives = 36/61 (59%), Gaps = 1/61 (1%) Query: 110 DLKEKQ-IESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTV 168 DL+EK+ +++++ S KGK+K R KE+K + +S G EAP+ + K+ ++ Sbjct: 662 DLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVY 721 Query: 169 P 169 P Sbjct: 722 P 722 >gi|35493868 otoferlin isoform b [Homo sapiens] Length = 1230 Score = 41.2 bits (95), Expect = 5e-04 Identities = 20/61 (32%), Positives = 36/61 (59%), Gaps = 1/61 (1%) Query: 110 DLKEKQ-IESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTV 168 DL+EK+ +++++ S KGK+K R KE+K + +S G EAP+ + K+ ++ Sbjct: 585 DLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVY 644 Query: 169 P 169 P Sbjct: 645 P 645 >gi|35493860 otoferlin isoform d [Homo sapiens] Length = 1230 Score = 41.2 bits (95), Expect = 5e-04 Identities = 20/61 (32%), Positives = 36/61 (59%), Gaps = 1/61 (1%) Query: 110 DLKEKQ-IESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTV 168 DL+EK+ +++++ S KGK+K R KE+K + +S G EAP+ + K+ ++ Sbjct: 585 DLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVY 644 Query: 169 P 169 P Sbjct: 645 P 645 >gi|34740331 otoferlin isoform a [Homo sapiens] Length = 1997 Score = 41.2 bits (95), Expect = 5e-04 Identities = 20/61 (32%), Positives = 36/61 (59%), Gaps = 1/61 (1%) Query: 110 DLKEKQ-IESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTV 168 DL+EK+ +++++ S KGK+K R KE+K + +S G EAP+ + K+ ++ Sbjct: 1352 DLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVY 1411 Query: 169 P 169 P Sbjct: 1412 P 1412 >gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sapiens] Length = 1954 Score = 38.5 bits (88), Expect = 0.003 Identities = 30/78 (38%), Positives = 42/78 (53%), Gaps = 10/78 (12%) Query: 103 DLARFEADLKEK-QIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKK 161 +L+ E DL+EK + E SDY S + K KKK + +KEKKA R K DE+ Sbjct: 74 ELSENEEDLEEKSESEGSDY-SPNKKKKKKLKDKKEKKAKR-----KKKDEDEDDNDDGC 127 Query: 162 LKLVRTVPLSGSILPVWG 179 LK ++ SG ++ WG Sbjct: 128 LKEPKS---SGQLMAEWG 142 >gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sapiens] Length = 1843 Score = 38.1 bits (87), Expect = 0.004 Identities = 37/171 (21%), Positives = 76/171 (44%), Gaps = 17/171 (9%) Query: 7 LEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSA------RSLSSEE 60 L+ LDS +NL F+L+ + LD+ +L+ ++ L M A + L SE+ Sbjct: 675 LKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK 734 Query: 61 KLAL--LKQIQEAYGKCKEFG------DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLK 112 + L+ ++ ++ K + D + Q +T E +K I++L+++L E Sbjct: 735 EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLE---M 791 Query: 113 EKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLK 163 E Q + + K+ + +KE K+ + D++ + K+L+ Sbjct: 792 ENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLR 842 >gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo sapiens] Length = 1870 Score = 38.1 bits (87), Expect = 0.004 Identities = 37/171 (21%), Positives = 76/171 (44%), Gaps = 17/171 (9%) Query: 7 LEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSA------RSLSSEE 60 L+ LDS +NL F+L+ + LD+ +L+ ++ L M A + L SE+ Sbjct: 675 LKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK 734 Query: 61 KLAL--LKQIQEAYGKCKEFG------DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLK 112 + L+ ++ ++ K + D + Q +T E +K I++L+++L E Sbjct: 735 EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLE---M 791 Query: 113 EKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLK 163 E Q + + K+ + +KE K+ + D++ + K+L+ Sbjct: 792 ENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLR 842 >gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] Length = 1946 Score = 37.7 bits (86), Expect = 0.005 Identities = 38/182 (20%), Positives = 80/182 (43%), Gaps = 15/182 (8%) Query: 8 EHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALL-- 65 + + DS+ L +++ Q+ + L++ DL+ E+D L T R+ ++ EKL L Sbjct: 1206 KRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYE 1265 Query: 66 KQIQEA---YGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDY- 121 +++ EA K + +D + + + +RRL+ EA + + E S++ Sbjct: 1266 ERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEK----EALINQLSREKSNFT 1321 Query: 122 -DSSSSKGKKKGRTQKEKKAARARSKGKNS----DEEAPKTAQKKLKLVRTVPLSGSILP 176 +G+ + T+ + A A K + E+ + + K +L RT+ + + Sbjct: 1322 RQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMV 1381 Query: 177 VW 178 W Sbjct: 1382 QW 1383 >gi|55770834 centromere protein F [Homo sapiens] Length = 3114 Score = 37.7 bits (86), Expect = 0.005 Identities = 46/161 (28%), Positives = 65/161 (40%), Gaps = 35/161 (21%) Query: 12 DSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLS---------SEEKL 62 D +ENL ELQ + + + E+ KAE++ L T+ ARSL EK Sbjct: 2154 DKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKE 2213 Query: 63 ALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEK-QIESSDY 121 L KQIQE G+ E LD L+ F++ L+EK Q E Sbjct: 2214 NLTKQIQEKQGQLSE----------------------LDKLLSSFKSLLEEKEQAEIQIK 2251 Query: 122 DSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKL 162 + S + + KE A A G D+E K ++ L Sbjct: 2252 EESKTAVEMLQNQLKELNEAVAALCG---DQEIMKATEQSL 2289 >gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo sapiens] Length = 1972 Score = 37.0 bits (84), Expect = 0.009 Identities = 34/168 (20%), Positives = 77/168 (45%), Gaps = 16/168 (9%) Query: 7 LEHYLDSIENLPFELQRNFQLM-----RDL---DQRTEDLKAEIDKLATEYMSSARSLSS 58 LE L + E+ L+ N Q + RDL D++ E+ + ++ + EY + Sbjct: 1551 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1610 Query: 59 EEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIES 118 + LA + ++ G K+ + + A++ E K +R+L + F+ +L++ + Sbjct: 1611 QRALAAAAK-KKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1668 Query: 119 SDYDSSSSKGKKKGRT------QKEKKAARARSKGKNSDEEAPKTAQK 160 + +++ + +KK ++ Q ++ A A K +D E + A++ Sbjct: 1669 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1716 Score = 33.5 bits (75), Expect = 0.100 Identities = 32/141 (22%), Positives = 62/141 (43%), Gaps = 20/141 (14%) Query: 28 MRDLDQRTEDLKAEIDKL---ATEYMSSARSLSSE-----EKLALLKQIQEAYGKCKEFG 79 M+D + ED +A D++ A E A+SL ++ E LA ++ ++ KE Sbjct: 1654 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1713 Query: 80 DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKK 139 +++ ++ + RRL+ +A+ E +L+E+Q G + + + +K Sbjct: 1714 AEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQ------------GNMEAMSDRVRK 1761 Query: 140 AARARSKGKNSDEEAPKTAQK 160 A + + N TAQK Sbjct: 1762 ATQQAEQLSNELATERSTAQK 1782 Score = 28.9 bits (63), Expect = 2.5 Identities = 36/171 (21%), Positives = 73/171 (42%), Gaps = 14/171 (8%) Query: 8 EHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEK--LALL 65 + + IENL + + L++ L+ E+D L + + + +S+ EK Sbjct: 1395 KRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD 1454 Query: 66 KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHI---RRLDTDL-ARFEADLKEKQIESSDY 121 + + E ++ D++ + + E K + R L+ L A+ E + K +++ Sbjct: 1455 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1514 Query: 122 DSSSSK---GKKKGRTQKEKKAARA-----RSKGKNSDEEAPKTAQKKLKL 164 D SSK GK +K K+A +++ + ++E T KL+L Sbjct: 1515 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1565 Score = 28.1 bits (61), Expect = 4.2 Identities = 29/155 (18%), Positives = 63/155 (40%), Gaps = 8/155 (5%) Query: 28 MRDLDQRTEDLKAEIDKLATEYMSSARSLS--------SEEKLALLKQIQEAYGKCKEFG 79 +R L++ L+ ++D+ + R +S S++KL EA + K+ Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1397 Query: 80 DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKK 139 +++ Q YE +L+ R + +L + ++ + S +KK R + Sbjct: 1398 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 1457 Query: 140 AARARSKGKNSDEEAPKTAQKKLKLVRTVPLSGSI 174 A K +DE A+ + K + + L+ ++ Sbjct: 1458 AEEKNISSKYADERDRAEAEAREKETKALSLARAL 1492 >gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo sapiens] Length = 1979 Score = 37.0 bits (84), Expect = 0.009 Identities = 34/168 (20%), Positives = 77/168 (45%), Gaps = 16/168 (9%) Query: 7 LEHYLDSIENLPFELQRNFQLM-----RDL---DQRTEDLKAEIDKLATEYMSSARSLSS 58 LE L + E+ L+ N Q + RDL D++ E+ + ++ + EY + Sbjct: 1558 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1617 Query: 59 EEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIES 118 + LA + ++ G K+ + + A++ E K +R+L + F+ +L++ + Sbjct: 1618 QRALAAAAK-KKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1675 Query: 119 SDYDSSSSKGKKKGRT------QKEKKAARARSKGKNSDEEAPKTAQK 160 + +++ + +KK ++ Q ++ A A K +D E + A++ Sbjct: 1676 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1723 Score = 33.5 bits (75), Expect = 0.100 Identities = 32/141 (22%), Positives = 62/141 (43%), Gaps = 20/141 (14%) Query: 28 MRDLDQRTEDLKAEIDKL---ATEYMSSARSLSSE-----EKLALLKQIQEAYGKCKEFG 79 M+D + ED +A D++ A E A+SL ++ E LA ++ ++ KE Sbjct: 1661 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1720 Query: 80 DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKK 139 +++ ++ + RRL+ +A+ E +L+E+Q G + + + +K Sbjct: 1721 AEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQ------------GNMEAMSDRVRK 1768 Query: 140 AARARSKGKNSDEEAPKTAQK 160 A + + N TAQK Sbjct: 1769 ATQQAEQLSNELATERSTAQK 1789 Score = 28.9 bits (63), Expect = 2.5 Identities = 36/171 (21%), Positives = 73/171 (42%), Gaps = 14/171 (8%) Query: 8 EHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEK--LALL 65 + + IENL + + L++ L+ E+D L + + + +S+ EK Sbjct: 1402 KRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD 1461 Query: 66 KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHI---RRLDTDL-ARFEADLKEKQIESSDY 121 + + E ++ D++ + + E K + R L+ L A+ E + K +++ Sbjct: 1462 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1521 Query: 122 DSSSSK---GKKKGRTQKEKKAARA-----RSKGKNSDEEAPKTAQKKLKL 164 D SSK GK +K K+A +++ + ++E T KL+L Sbjct: 1522 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1572 Score = 28.1 bits (61), Expect = 4.2 Identities = 29/155 (18%), Positives = 63/155 (40%), Gaps = 8/155 (5%) Query: 28 MRDLDQRTEDLKAEIDKLATEYMSSARSLS--------SEEKLALLKQIQEAYGKCKEFG 79 +R L++ L+ ++D+ + R +S S++KL EA + K+ Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1404 Query: 80 DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKK 139 +++ Q YE +L+ R + +L + ++ + S +KK R + Sbjct: 1405 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 1464 Query: 140 AARARSKGKNSDEEAPKTAQKKLKLVRTVPLSGSI 174 A K +DE A+ + K + + L+ ++ Sbjct: 1465 AEEKNISSKYADERDRAEAEAREKETKALSLARAL 1499 >gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo sapiens] Length = 1945 Score = 37.0 bits (84), Expect = 0.009 Identities = 34/168 (20%), Positives = 77/168 (45%), Gaps = 16/168 (9%) Query: 7 LEHYLDSIENLPFELQRNFQLM-----RDL---DQRTEDLKAEIDKLATEYMSSARSLSS 58 LE L + E+ L+ N Q + RDL D++ E+ + ++ + EY + Sbjct: 1558 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1617 Query: 59 EEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIES 118 + LA + ++ G K+ + + A++ E K +R+L + F+ +L++ + Sbjct: 1618 QRALAAAAK-KKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1675 Query: 119 SDYDSSSSKGKKKGRT------QKEKKAARARSKGKNSDEEAPKTAQK 160 + +++ + +KK ++ Q ++ A A K +D E + A++ Sbjct: 1676 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1723 Score = 33.5 bits (75), Expect = 0.100 Identities = 32/141 (22%), Positives = 62/141 (43%), Gaps = 20/141 (14%) Query: 28 MRDLDQRTEDLKAEIDKL---ATEYMSSARSLSSE-----EKLALLKQIQEAYGKCKEFG 79 M+D + ED +A D++ A E A+SL ++ E LA ++ ++ KE Sbjct: 1661 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1720 Query: 80 DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKK 139 +++ ++ + RRL+ +A+ E +L+E+Q G + + + +K Sbjct: 1721 AEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQ------------GNMEAMSDRVRK 1768 Query: 140 AARARSKGKNSDEEAPKTAQK 160 A + + N TAQK Sbjct: 1769 ATQQAEQLSNELATERSTAQK 1789 Score = 28.9 bits (63), Expect = 2.5 Identities = 36/171 (21%), Positives = 73/171 (42%), Gaps = 14/171 (8%) Query: 8 EHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEK--LALL 65 + + IENL + + L++ L+ E+D L + + + +S+ EK Sbjct: 1402 KRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD 1461 Query: 66 KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHI---RRLDTDL-ARFEADLKEKQIESSDY 121 + + E ++ D++ + + E K + R L+ L A+ E + K +++ Sbjct: 1462 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1521 Query: 122 DSSSSK---GKKKGRTQKEKKAARA-----RSKGKNSDEEAPKTAQKKLKL 164 D SSK GK +K K+A +++ + ++E T KL+L Sbjct: 1522 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1572 Score = 28.1 bits (61), Expect = 4.2 Identities = 29/155 (18%), Positives = 63/155 (40%), Gaps = 8/155 (5%) Query: 28 MRDLDQRTEDLKAEIDKLATEYMSSARSLS--------SEEKLALLKQIQEAYGKCKEFG 79 +R L++ L+ ++D+ + R +S S++KL EA + K+ Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1404 Query: 80 DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKK 139 +++ Q YE +L+ R + +L + ++ + S +KK R + Sbjct: 1405 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 1464 Query: 140 AARARSKGKNSDEEAPKTAQKKLKLVRTVPLSGSI 174 A K +DE A+ + K + + L+ ++ Sbjct: 1465 AEEKNISSKYADERDRAEAEAREKETKALSLARAL 1499 >gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo sapiens] Length = 1938 Score = 37.0 bits (84), Expect = 0.009 Identities = 34/168 (20%), Positives = 77/168 (45%), Gaps = 16/168 (9%) Query: 7 LEHYLDSIENLPFELQRNFQLM-----RDL---DQRTEDLKAEIDKLATEYMSSARSLSS 58 LE L + E+ L+ N Q + RDL D++ E+ + ++ + EY + Sbjct: 1551 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1610 Query: 59 EEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIES 118 + LA + ++ G K+ + + A++ E K +R+L + F+ +L++ + Sbjct: 1611 QRALAAAAK-KKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1668 Query: 119 SDYDSSSSKGKKKGRT------QKEKKAARARSKGKNSDEEAPKTAQK 160 + +++ + +KK ++ Q ++ A A K +D E + A++ Sbjct: 1669 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1716 Score = 33.5 bits (75), Expect = 0.100 Identities = 32/141 (22%), Positives = 62/141 (43%), Gaps = 20/141 (14%) Query: 28 MRDLDQRTEDLKAEIDKL---ATEYMSSARSLSSE-----EKLALLKQIQEAYGKCKEFG 79 M+D + ED +A D++ A E A+SL ++ E LA ++ ++ KE Sbjct: 1654 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1713 Query: 80 DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKK 139 +++ ++ + RRL+ +A+ E +L+E+Q G + + + +K Sbjct: 1714 AEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQ------------GNMEAMSDRVRK 1761 Query: 140 AARARSKGKNSDEEAPKTAQK 160 A + + N TAQK Sbjct: 1762 ATQQAEQLSNELATERSTAQK 1782 Score = 28.9 bits (63), Expect = 2.5 Identities = 36/171 (21%), Positives = 73/171 (42%), Gaps = 14/171 (8%) Query: 8 EHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEK--LALL 65 + + IENL + + L++ L+ E+D L + + + +S+ EK Sbjct: 1395 KRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD 1454 Query: 66 KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHI---RRLDTDL-ARFEADLKEKQIESSDY 121 + + E ++ D++ + + E K + R L+ L A+ E + K +++ Sbjct: 1455 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1514 Query: 122 DSSSSK---GKKKGRTQKEKKAARA-----RSKGKNSDEEAPKTAQKKLKL 164 D SSK GK +K K+A +++ + ++E T KL+L Sbjct: 1515 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1565 Score = 28.1 bits (61), Expect = 4.2 Identities = 29/155 (18%), Positives = 63/155 (40%), Gaps = 8/155 (5%) Query: 28 MRDLDQRTEDLKAEIDKLATEYMSSARSLS--------SEEKLALLKQIQEAYGKCKEFG 79 +R L++ L+ ++D+ + R +S S++KL EA + K+ Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1397 Query: 80 DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKK 139 +++ Q YE +L+ R + +L + ++ + S +KK R + Sbjct: 1398 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 1457 Query: 140 AARARSKGKNSDEEAPKTAQKKLKLVRTVPLSGSI 174 A K +DE A+ + K + + L+ ++ Sbjct: 1458 AEEKNISSKYADERDRAEAEAREKETKALSLARAL 1492 >gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo sapiens] Length = 1935 Score = 36.6 bits (83), Expect = 0.012 Identities = 33/144 (22%), Positives = 71/144 (49%), Gaps = 20/144 (13%) Query: 33 QRTEDLKAEIDKLATEYMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQT--- 89 Q +DL+AE DK+ T ++ K+ L +Q+ + G ++ + KV++ ++ Sbjct: 1005 QALDDLQAEEDKVNT---------LTKAKVKLEQQVDDLEGSLEQ--EKKVRMDLERAKR 1053 Query: 90 -----YEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKG-RTQKEKKAARA 143 ++ + I L+ D + + LK+K E + ++ + G + QK+ K +A Sbjct: 1054 KLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQA 1113 Query: 144 RSKGKNSDEEAPKTAQKKLKLVRT 167 R + + EA +TA+ K++ +R+ Sbjct: 1114 RIEELEEELEAERTARAKVEKLRS 1137 Score = 29.3 bits (64), Expect = 1.9 Identities = 33/167 (19%), Positives = 70/167 (41%), Gaps = 21/167 (12%) Query: 11 LDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALLKQIQE 70 LD +L+ N ++ ++R L+AE+++L + RS KLA + I+ Sbjct: 1657 LDDAVRANDDLKENIAIV---ERRNNLLQAELEELRAVVEQTERS----RKLAEQELIET 1709 Query: 71 AYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSK--- 127 + ++VQL + +++D DL++ + +++E E + + + K Sbjct: 1710 S---------ERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAIT 1760 Query: 128 --GKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSG 172 +KE+ + + K + E+ K Q +L + L G Sbjct: 1761 DAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKG 1807 Score = 27.7 bits (60), Expect = 5.5 Identities = 37/169 (21%), Positives = 69/169 (40%), Gaps = 17/169 (10%) Query: 2 AAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEK 61 AA + +H DS+ L ++ ++ + L++ + K E+D + + ++ ++ EK Sbjct: 1189 AAALRKKH-ADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEK 1247 Query: 62 L--ALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESS 119 + L Q+ E K +E L Q +L T+ L EK+ Sbjct: 1248 MCRTLEDQMNEHRSKAEETQRSVNDLTSQR--------AKLQTENGELSRQLDEKEA--- 1296 Query: 120 DYDSSSSKGKKKGRTQKE--KKAARARSKGKNSDEEAPKTAQKKLKLVR 166 S ++GK Q E K+ K KN+ A ++A+ L+R Sbjct: 1297 -LISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLR 1344 >gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapiens] Length = 1002 Score = 36.6 bits (83), Expect = 0.012 Identities = 26/111 (23%), Positives = 53/111 (47%), Gaps = 5/111 (4%) Query: 11 LDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKL-----ALL 65 L++++N + R R+L ++ +L++ KL E M +L SE+ + L Sbjct: 525 LETMQNDRTTISRALSQNRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKRELGKKL 584 Query: 66 KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQI 116 ++QE + KE + K Q A + D+++ L +A ++ EK++ Sbjct: 585 GELQEKLSELKETVELKSQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEV 635 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.127 0.339 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 5,703,763 Number of Sequences: 37866 Number of extensions: 222376 Number of successful extensions: 3078 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 133 Number of HSP's successfully gapped in prelim test: 274 Number of HSP's that attempted gapping in prelim test: 2216 Number of HSP's gapped (non-prelim): 991 length of query: 179 length of database: 18,247,518 effective HSP length: 96 effective length of query: 83 effective length of database: 14,612,382 effective search space: 1212827706 effective search space used: 1212827706 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.