Guide to the Human Genome
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Search of human proteins with 189083832

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189083832 inhibitor of growth family, member 4 isoform 6
[Homo sapiens]
         (179 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189083832 inhibitor of growth family, member 4 isoform 6 [Hom...   350   4e-97
gi|189083821 inhibitor of growth family, member 4 isoform 9 [Hom...   327   3e-90
gi|38201670 inhibitor of growth family, member 4 isoform 1 [Homo...   318   1e-87
gi|189083826 inhibitor of growth family, member 4 isoform 3 [Hom...   314   2e-86
gi|189083828 inhibitor of growth family, member 4 isoform 4 [Hom...   313   4e-86
gi|189083830 inhibitor of growth family, member 4 isoform 5 [Hom...   265   2e-71
gi|18644730 inhibitor of growth family, member 5 [Homo sapiens]       215   2e-56
gi|38201667 inhibitor of growth family, member 1 isoform A [Homo...    87   6e-18
gi|38201655 inhibitor of growth family, member 3 isoform 1 [Homo...    85   4e-17
gi|4504695 inhibitor of growth family, member 2 [Homo sapiens]         73   1e-13
gi|38201659 inhibitor of growth family, member 3 isoform 3 [Homo...    60   8e-10
gi|38201663 inhibitor of growth family, member 1 isoform C [Homo...    47   1e-05
gi|38201661 inhibitor of growth family, member 1 isoform D [Homo...    47   1e-05
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    47   1e-05
gi|38201665 inhibitor of growth family, member 1 isoform B [Homo...    43   2e-04
gi|35493853 otoferlin isoform c [Homo sapiens]                         41   5e-04
gi|35493868 otoferlin isoform b [Homo sapiens]                         41   5e-04
gi|35493860 otoferlin isoform d [Homo sapiens]                         41   5e-04
gi|34740331 otoferlin isoform a [Homo sapiens]                         41   5e-04
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa...    39   0.003
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    38   0.004
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    38   0.004
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]               38   0.005
gi|55770834 centromere protein F [Homo sapiens]                        38   0.005
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    37   0.009
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    37   0.009
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    37   0.009
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    37   0.009
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    37   0.012
gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi...    37   0.012

>gi|189083832 inhibitor of growth family, member 4 isoform 6 [Homo
           sapiens]
          Length = 179

 Score =  350 bits (898), Expect = 4e-97
 Identities = 179/179 (100%), Positives = 179/179 (100%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE
Sbjct: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120

Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSGSILPVWG 179
           YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSGSILPVWG
Sbjct: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSGSILPVWG 179


>gi|189083821 inhibitor of growth family, member 4 isoform 9 [Homo
           sapiens]
          Length = 249

 Score =  327 bits (839), Expect = 3e-90
 Identities = 169/172 (98%), Positives = 169/172 (98%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE
Sbjct: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120

Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSG 172
           YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRT P  G
Sbjct: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYG 172


>gi|38201670 inhibitor of growth family, member 4 isoform 1 [Homo
           sapiens]
          Length = 248

 Score =  318 bits (816), Expect = 1e-87
 Identities = 167/172 (97%), Positives = 167/172 (97%), Gaps = 1/172 (0%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE
Sbjct: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120

Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSG 172
           YDSSSSKG KK RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRT P  G
Sbjct: 121 YDSSSSKG-KKSRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYG 171


>gi|189083826 inhibitor of growth family, member 4 isoform 3 [Homo
           sapiens]
          Length = 246

 Score =  314 bits (805), Expect = 2e-86
 Identities = 165/172 (95%), Positives = 166/172 (96%), Gaps = 3/172 (1%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE
Sbjct: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120

Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSG 172
           YDSSSS   K+GRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRT P  G
Sbjct: 121 YDSSSS---KEGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYG 169


>gi|189083828 inhibitor of growth family, member 4 isoform 4 [Homo
           sapiens]
          Length = 245

 Score =  313 bits (803), Expect = 4e-86
 Identities = 165/172 (95%), Positives = 165/172 (95%), Gaps = 4/172 (2%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE
Sbjct: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120

Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSG 172
           YDSSSS    KGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRT P  G
Sbjct: 121 YDSSSS----KGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYG 168


>gi|189083830 inhibitor of growth family, member 4 isoform 5 [Homo
           sapiens]
          Length = 225

 Score =  265 bits (677), Expect = 2e-71
 Identities = 144/172 (83%), Positives = 145/172 (84%), Gaps = 24/172 (13%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MAAGMYLEHYLD+                        LKAEIDKLATEYMSSARSLSSEE
Sbjct: 1   MAAGMYLEHYLDN------------------------LKAEIDKLATEYMSSARSLSSEE 36

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 37  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 96

Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSG 172
           YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRT P  G
Sbjct: 97  YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYG 148


>gi|18644730 inhibitor of growth family, member 5 [Homo sapiens]
          Length = 240

 Score =  215 bits (547), Expect = 2e-56
 Identities = 108/161 (67%), Positives = 132/161 (81%), Gaps = 2/161 (1%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MA  MYLEHYLDSIENLP ELQRNFQLMR+LDQRTED KAEID LA EY+S+ ++LS ++
Sbjct: 1   MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQ 60

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           ++  L++IQ AY KCKE+ DDKVQLAMQTYEMVDKHIRRLD DLARFEADLK+K +E SD
Sbjct: 61  RVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MEGSD 119

Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKK 161
           ++SS  +G KKGR QKEK+ +R R + + S+E+ PK  + K
Sbjct: 120 FESSGGRGLKKGRGQKEKRGSRGRGR-RTSEEDTPKKKKHK 159


>gi|38201667 inhibitor of growth family, member 1 isoform A [Homo
           sapiens]
          Length = 279

 Score = 87.4 bits (215), Expect = 6e-18
 Identities = 47/149 (31%), Positives = 84/149 (56%), Gaps = 4/149 (2%)

Query: 6   YLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALL 65
           Y+E YLDSIE+LPF+LQRN  LMR++D + +++  E+D+    Y   +R     +K  +L
Sbjct: 15  YVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDEC---YERFSRETDGAQKRRML 71

Query: 66  KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSS 125
             +Q A  + +E GD+K+Q+  Q  E+V+   R++D+ +  FEA  +      +   + +
Sbjct: 72  HCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGA 131

Query: 126 SKGKKKGRTQKEK-KAARARSKGKNSDEE 153
            + K +   Q +K  + R+R +  N + E
Sbjct: 132 DRPKGEAAAQADKPNSKRSRRQRNNENRE 160


>gi|38201655 inhibitor of growth family, member 3 isoform 1 [Homo
           sapiens]
          Length = 418

 Score = 84.7 bits (208), Expect = 4e-17
 Identities = 39/108 (36%), Positives = 71/108 (65%)

Query: 5   MYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLAL 64
           +YLE YL+ IE LP +L+  F  MR++D + ++   ++++  +E+  +A+    E +   
Sbjct: 2   LYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREEQ 61

Query: 65  LKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLK 112
           +  I++ Y K  E  D+KVQLA Q Y++VD+H+R+LD +LA+F+ +L+
Sbjct: 62  MASIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELE 109


>gi|4504695 inhibitor of growth family, member 2 [Homo sapiens]
          Length = 280

 Score = 72.8 bits (177), Expect = 1e-13
 Identities = 42/161 (26%), Positives = 86/161 (53%), Gaps = 8/161 (4%)

Query: 6   YLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALL 65
           Y++ YL+ +E+LP ++QRN  ++R+LD + ++   EID +  +Y    +     +K  L 
Sbjct: 27  YVQDYLECVESLPHDMQRNVSVLRELDNKYQETLKEIDDVYEKY---KKEDDLNQKKRLQ 83

Query: 66  KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLK-EKQIESSDYDSS 124
           + +Q A    +E GD+K+Q+  Q  E+V+   R+++     F+   + E+  + +  DSS
Sbjct: 84  QLLQRALINSQELGDEKIQIVTQMLELVENRARQMELHSQCFQDPAESERASDKAKMDSS 143

Query: 125 ----SSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKK 161
               SS+  ++ RT + +      +  ++ D++ PK  + K
Sbjct: 144 QPERSSRRPRRQRTSESRDLCHMANGIEDCDDQPPKEKKSK 184


>gi|38201659 inhibitor of growth family, member 3 isoform 3 [Homo
          sapiens]
          Length = 92

 Score = 60.5 bits (145), Expect = 8e-10
 Identities = 29/88 (32%), Positives = 53/88 (60%)

Query: 5  MYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLAL 64
          +YLE YL+ IE LP +L+  F  MR++D + ++   ++++  +E+  +A+    E +   
Sbjct: 2  LYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREEQ 61

Query: 65 LKQIQEAYGKCKEFGDDKVQLAMQTYEM 92
          +  I++ Y K  E  D+KVQLA Q Y++
Sbjct: 62 MASIKKDYYKALEDADEKVQLANQIYDL 89


>gi|38201663 inhibitor of growth family, member 1 isoform C [Homo
           sapiens]
          Length = 235

 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 26/106 (24%), Positives = 52/106 (49%), Gaps = 1/106 (0%)

Query: 49  YMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFE 108
           Y   +R     +K  +L  +Q A  + +E GD+K+Q+  Q  E+V+   R++D+ +  FE
Sbjct: 11  YERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFE 70

Query: 109 ADLKEKQIESSDYDSSSSKGKKKGRTQKEK-KAARARSKGKNSDEE 153
           A  +      +   + + + K +   Q +K  + R+R +  N + E
Sbjct: 71  AQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRE 116


>gi|38201661 inhibitor of growth family, member 1 isoform D [Homo
           sapiens]
          Length = 422

 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 26/106 (24%), Positives = 52/106 (49%), Gaps = 1/106 (0%)

Query: 49  YMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFE 108
           Y   +R     +K  +L  +Q A  + +E GD+K+Q+  Q  E+V+   R++D+ +  FE
Sbjct: 198 YERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFE 257

Query: 109 ADLKEKQIESSDYDSSSSKGKKKGRTQKEK-KAARARSKGKNSDEE 153
           A  +      +   + + + K +   Q +K  + R+R +  N + E
Sbjct: 258 AQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRE 303


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 44/168 (26%), Positives = 78/168 (46%), Gaps = 13/168 (7%)

Query: 1    MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
            M A +  +H  DS+  L  ++    ++ + L++   + K EID L++   S ++S ++ E
Sbjct: 1189 MVAALRKKH-ADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLE 1247

Query: 61   KL--ALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIES 118
            K+   L  Q+ EA GK +E      +L  Q          RL T+       L+EK  ES
Sbjct: 1248 KICRTLEDQLSEARGKNEEIQRSLSELTTQK--------SRLQTEAGELSRQLEEK--ES 1297

Query: 119  SDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVR 166
                 S SK     +T++ K+     +K KN+   A ++++    L+R
Sbjct: 1298 IVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLR 1345


>gi|38201665 inhibitor of growth family, member 1 isoform B [Homo
           sapiens]
          Length = 210

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 23/91 (25%), Positives = 47/91 (51%), Gaps = 1/91 (1%)

Query: 64  LLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDS 123
           +L  +Q A  + +E GD+K+Q+  Q  E+V+   R++D+ +  FEA  +      +   +
Sbjct: 1   MLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKA 60

Query: 124 SSSKGKKKGRTQKEK-KAARARSKGKNSDEE 153
            + + K +   Q +K  + R+R +  N + E
Sbjct: 61  GADRPKGEAAAQADKPNSKRSRRQRNNENRE 91


>gi|35493853 otoferlin isoform c [Homo sapiens]
          Length = 1307

 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 20/61 (32%), Positives = 36/61 (59%), Gaps = 1/61 (1%)

Query: 110 DLKEKQ-IESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTV 168
           DL+EK+ +++++    S KGK+K R  KE+K  + +S G     EAP+  + K+  ++  
Sbjct: 662 DLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVY 721

Query: 169 P 169
           P
Sbjct: 722 P 722


>gi|35493868 otoferlin isoform b [Homo sapiens]
          Length = 1230

 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 20/61 (32%), Positives = 36/61 (59%), Gaps = 1/61 (1%)

Query: 110 DLKEKQ-IESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTV 168
           DL+EK+ +++++    S KGK+K R  KE+K  + +S G     EAP+  + K+  ++  
Sbjct: 585 DLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVY 644

Query: 169 P 169
           P
Sbjct: 645 P 645


>gi|35493860 otoferlin isoform d [Homo sapiens]
          Length = 1230

 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 20/61 (32%), Positives = 36/61 (59%), Gaps = 1/61 (1%)

Query: 110 DLKEKQ-IESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTV 168
           DL+EK+ +++++    S KGK+K R  KE+K  + +S G     EAP+  + K+  ++  
Sbjct: 585 DLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVY 644

Query: 169 P 169
           P
Sbjct: 645 P 645


>gi|34740331 otoferlin isoform a [Homo sapiens]
          Length = 1997

 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 20/61 (32%), Positives = 36/61 (59%), Gaps = 1/61 (1%)

Query: 110  DLKEKQ-IESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTV 168
            DL+EK+ +++++    S KGK+K R  KE+K  + +S G     EAP+  + K+  ++  
Sbjct: 1352 DLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVY 1411

Query: 169  P 169
            P
Sbjct: 1412 P 1412


>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
           sapiens]
          Length = 1954

 Score = 38.5 bits (88), Expect = 0.003
 Identities = 30/78 (38%), Positives = 42/78 (53%), Gaps = 10/78 (12%)

Query: 103 DLARFEADLKEK-QIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKK 161
           +L+  E DL+EK + E SDY S + K KKK + +KEKKA R     K  DE+        
Sbjct: 74  ELSENEEDLEEKSESEGSDY-SPNKKKKKKLKDKKEKKAKR-----KKKDEDEDDNDDGC 127

Query: 162 LKLVRTVPLSGSILPVWG 179
           LK  ++   SG ++  WG
Sbjct: 128 LKEPKS---SGQLMAEWG 142


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 38.1 bits (87), Expect = 0.004
 Identities = 37/171 (21%), Positives = 76/171 (44%), Gaps = 17/171 (9%)

Query: 7   LEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSA------RSLSSEE 60
           L+  LDS +NL F+L+   +    LD+   +L+  ++ L    M  A      + L SE+
Sbjct: 675 LKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK 734

Query: 61  KLAL--LKQIQEAYGKCKEFG------DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLK 112
           +     L+ ++ ++ K +         D + Q   +T E  +K I++L+++L   E    
Sbjct: 735 EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLE---M 791

Query: 113 EKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLK 163
           E Q    + +      K+  + +KE K+    +     D++  +   K+L+
Sbjct: 792 ENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLR 842


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 38.1 bits (87), Expect = 0.004
 Identities = 37/171 (21%), Positives = 76/171 (44%), Gaps = 17/171 (9%)

Query: 7   LEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSA------RSLSSEE 60
           L+  LDS +NL F+L+   +    LD+   +L+  ++ L    M  A      + L SE+
Sbjct: 675 LKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK 734

Query: 61  KLAL--LKQIQEAYGKCKEFG------DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLK 112
           +     L+ ++ ++ K +         D + Q   +T E  +K I++L+++L   E    
Sbjct: 735 EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLE---M 791

Query: 113 EKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLK 163
           E Q    + +      K+  + +KE K+    +     D++  +   K+L+
Sbjct: 792 ENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLR 842


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 37.7 bits (86), Expect = 0.005
 Identities = 38/182 (20%), Positives = 80/182 (43%), Gaps = 15/182 (8%)

Query: 8    EHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALL-- 65
            + + DS+  L  +++   Q+ + L++   DL+ E+D L T      R+ ++ EKL  L  
Sbjct: 1206 KRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYE 1265

Query: 66   KQIQEA---YGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDY- 121
            +++ EA     K  +  +D      + +    + +RRL+      EA + +   E S++ 
Sbjct: 1266 ERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEK----EALINQLSREKSNFT 1321

Query: 122  -DSSSSKGKKKGRTQKEKKAARARSKGKNS----DEEAPKTAQKKLKLVRTVPLSGSILP 176
                  +G+ +  T+ +   A A  K +       E+  +  + K +L RT+    + + 
Sbjct: 1322 RQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMV 1381

Query: 177  VW 178
             W
Sbjct: 1382 QW 1383


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 37.7 bits (86), Expect = 0.005
 Identities = 46/161 (28%), Positives = 65/161 (40%), Gaps = 35/161 (21%)

Query: 12   DSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLS---------SEEKL 62
            D +ENL  ELQ + +    +    E+ KAE++ L T+    ARSL            EK 
Sbjct: 2154 DKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKE 2213

Query: 63   ALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEK-QIESSDY 121
             L KQIQE  G+  E                      LD  L+ F++ L+EK Q E    
Sbjct: 2214 NLTKQIQEKQGQLSE----------------------LDKLLSSFKSLLEEKEQAEIQIK 2251

Query: 122  DSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKL 162
            + S +  +      KE   A A   G   D+E  K  ++ L
Sbjct: 2252 EESKTAVEMLQNQLKELNEAVAALCG---DQEIMKATEQSL 2289


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 37.0 bits (84), Expect = 0.009
 Identities = 34/168 (20%), Positives = 77/168 (45%), Gaps = 16/168 (9%)

Query: 7    LEHYLDSIENLPFELQRNFQLM-----RDL---DQRTEDLKAEIDKLATEYMSSARSLSS 58
            LE  L + E+    L+ N Q +     RDL   D++ E+ + ++ +   EY +       
Sbjct: 1551 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1610

Query: 59   EEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIES 118
            +  LA   + ++  G  K+  + +   A++  E   K +R+L   +  F+ +L++ +   
Sbjct: 1611 QRALAAAAK-KKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1668

Query: 119  SDYDSSSSKGKKKGRT------QKEKKAARARSKGKNSDEEAPKTAQK 160
             +  +++ + +KK ++      Q ++  A A    K +D E  + A++
Sbjct: 1669 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1716



 Score = 33.5 bits (75), Expect = 0.100
 Identities = 32/141 (22%), Positives = 62/141 (43%), Gaps = 20/141 (14%)

Query: 28   MRDLDQRTEDLKAEIDKL---ATEYMSSARSLSSE-----EKLALLKQIQEAYGKCKEFG 79
            M+D  +  ED +A  D++   A E    A+SL ++     E LA  ++ ++     KE  
Sbjct: 1654 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1713

Query: 80   DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKK 139
             +++  ++     +    RRL+  +A+ E +L+E+Q            G  +  + + +K
Sbjct: 1714 AEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQ------------GNMEAMSDRVRK 1761

Query: 140  AARARSKGKNSDEEAPKTAQK 160
            A +   +  N       TAQK
Sbjct: 1762 ATQQAEQLSNELATERSTAQK 1782



 Score = 28.9 bits (63), Expect = 2.5
 Identities = 36/171 (21%), Positives = 73/171 (42%), Gaps = 14/171 (8%)

Query: 8    EHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEK--LALL 65
            + +   IENL  + +        L++    L+ E+D L  +  +  + +S+ EK      
Sbjct: 1395 KRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD 1454

Query: 66   KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHI---RRLDTDL-ARFEADLKEKQIESSDY 121
            + + E      ++ D++ +   +  E   K +   R L+  L A+ E +   K +++   
Sbjct: 1455 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1514

Query: 122  DSSSSK---GKKKGRTQKEKKAARA-----RSKGKNSDEEAPKTAQKKLKL 164
            D  SSK   GK     +K K+A        +++ +  ++E   T   KL+L
Sbjct: 1515 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1565



 Score = 28.1 bits (61), Expect = 4.2
 Identities = 29/155 (18%), Positives = 63/155 (40%), Gaps = 8/155 (5%)

Query: 28   MRDLDQRTEDLKAEIDKLATEYMSSARSLS--------SEEKLALLKQIQEAYGKCKEFG 79
            +R L++    L+ ++D+      +  R +S        S++KL       EA  + K+  
Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1397

Query: 80   DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKK 139
              +++   Q YE       +L+    R + +L +  ++  +     S  +KK R   +  
Sbjct: 1398 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 1457

Query: 140  AARARSKGKNSDEEAPKTAQKKLKLVRTVPLSGSI 174
            A       K +DE     A+ + K  + + L+ ++
Sbjct: 1458 AEEKNISSKYADERDRAEAEAREKETKALSLARAL 1492


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 37.0 bits (84), Expect = 0.009
 Identities = 34/168 (20%), Positives = 77/168 (45%), Gaps = 16/168 (9%)

Query: 7    LEHYLDSIENLPFELQRNFQLM-----RDL---DQRTEDLKAEIDKLATEYMSSARSLSS 58
            LE  L + E+    L+ N Q +     RDL   D++ E+ + ++ +   EY +       
Sbjct: 1558 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1617

Query: 59   EEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIES 118
            +  LA   + ++  G  K+  + +   A++  E   K +R+L   +  F+ +L++ +   
Sbjct: 1618 QRALAAAAK-KKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1675

Query: 119  SDYDSSSSKGKKKGRT------QKEKKAARARSKGKNSDEEAPKTAQK 160
             +  +++ + +KK ++      Q ++  A A    K +D E  + A++
Sbjct: 1676 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1723



 Score = 33.5 bits (75), Expect = 0.100
 Identities = 32/141 (22%), Positives = 62/141 (43%), Gaps = 20/141 (14%)

Query: 28   MRDLDQRTEDLKAEIDKL---ATEYMSSARSLSSE-----EKLALLKQIQEAYGKCKEFG 79
            M+D  +  ED +A  D++   A E    A+SL ++     E LA  ++ ++     KE  
Sbjct: 1661 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1720

Query: 80   DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKK 139
             +++  ++     +    RRL+  +A+ E +L+E+Q            G  +  + + +K
Sbjct: 1721 AEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQ------------GNMEAMSDRVRK 1768

Query: 140  AARARSKGKNSDEEAPKTAQK 160
            A +   +  N       TAQK
Sbjct: 1769 ATQQAEQLSNELATERSTAQK 1789



 Score = 28.9 bits (63), Expect = 2.5
 Identities = 36/171 (21%), Positives = 73/171 (42%), Gaps = 14/171 (8%)

Query: 8    EHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEK--LALL 65
            + +   IENL  + +        L++    L+ E+D L  +  +  + +S+ EK      
Sbjct: 1402 KRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD 1461

Query: 66   KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHI---RRLDTDL-ARFEADLKEKQIESSDY 121
            + + E      ++ D++ +   +  E   K +   R L+  L A+ E +   K +++   
Sbjct: 1462 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1521

Query: 122  DSSSSK---GKKKGRTQKEKKAARA-----RSKGKNSDEEAPKTAQKKLKL 164
            D  SSK   GK     +K K+A        +++ +  ++E   T   KL+L
Sbjct: 1522 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1572



 Score = 28.1 bits (61), Expect = 4.2
 Identities = 29/155 (18%), Positives = 63/155 (40%), Gaps = 8/155 (5%)

Query: 28   MRDLDQRTEDLKAEIDKLATEYMSSARSLS--------SEEKLALLKQIQEAYGKCKEFG 79
            +R L++    L+ ++D+      +  R +S        S++KL       EA  + K+  
Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1404

Query: 80   DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKK 139
              +++   Q YE       +L+    R + +L +  ++  +     S  +KK R   +  
Sbjct: 1405 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 1464

Query: 140  AARARSKGKNSDEEAPKTAQKKLKLVRTVPLSGSI 174
            A       K +DE     A+ + K  + + L+ ++
Sbjct: 1465 AEEKNISSKYADERDRAEAEAREKETKALSLARAL 1499


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 37.0 bits (84), Expect = 0.009
 Identities = 34/168 (20%), Positives = 77/168 (45%), Gaps = 16/168 (9%)

Query: 7    LEHYLDSIENLPFELQRNFQLM-----RDL---DQRTEDLKAEIDKLATEYMSSARSLSS 58
            LE  L + E+    L+ N Q +     RDL   D++ E+ + ++ +   EY +       
Sbjct: 1558 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1617

Query: 59   EEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIES 118
            +  LA   + ++  G  K+  + +   A++  E   K +R+L   +  F+ +L++ +   
Sbjct: 1618 QRALAAAAK-KKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1675

Query: 119  SDYDSSSSKGKKKGRT------QKEKKAARARSKGKNSDEEAPKTAQK 160
             +  +++ + +KK ++      Q ++  A A    K +D E  + A++
Sbjct: 1676 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1723



 Score = 33.5 bits (75), Expect = 0.100
 Identities = 32/141 (22%), Positives = 62/141 (43%), Gaps = 20/141 (14%)

Query: 28   MRDLDQRTEDLKAEIDKL---ATEYMSSARSLSSE-----EKLALLKQIQEAYGKCKEFG 79
            M+D  +  ED +A  D++   A E    A+SL ++     E LA  ++ ++     KE  
Sbjct: 1661 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1720

Query: 80   DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKK 139
             +++  ++     +    RRL+  +A+ E +L+E+Q            G  +  + + +K
Sbjct: 1721 AEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQ------------GNMEAMSDRVRK 1768

Query: 140  AARARSKGKNSDEEAPKTAQK 160
            A +   +  N       TAQK
Sbjct: 1769 ATQQAEQLSNELATERSTAQK 1789



 Score = 28.9 bits (63), Expect = 2.5
 Identities = 36/171 (21%), Positives = 73/171 (42%), Gaps = 14/171 (8%)

Query: 8    EHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEK--LALL 65
            + +   IENL  + +        L++    L+ E+D L  +  +  + +S+ EK      
Sbjct: 1402 KRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD 1461

Query: 66   KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHI---RRLDTDL-ARFEADLKEKQIESSDY 121
            + + E      ++ D++ +   +  E   K +   R L+  L A+ E +   K +++   
Sbjct: 1462 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1521

Query: 122  DSSSSK---GKKKGRTQKEKKAARA-----RSKGKNSDEEAPKTAQKKLKL 164
            D  SSK   GK     +K K+A        +++ +  ++E   T   KL+L
Sbjct: 1522 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1572



 Score = 28.1 bits (61), Expect = 4.2
 Identities = 29/155 (18%), Positives = 63/155 (40%), Gaps = 8/155 (5%)

Query: 28   MRDLDQRTEDLKAEIDKLATEYMSSARSLS--------SEEKLALLKQIQEAYGKCKEFG 79
            +R L++    L+ ++D+      +  R +S        S++KL       EA  + K+  
Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1404

Query: 80   DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKK 139
              +++   Q YE       +L+    R + +L +  ++  +     S  +KK R   +  
Sbjct: 1405 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 1464

Query: 140  AARARSKGKNSDEEAPKTAQKKLKLVRTVPLSGSI 174
            A       K +DE     A+ + K  + + L+ ++
Sbjct: 1465 AEEKNISSKYADERDRAEAEAREKETKALSLARAL 1499


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 37.0 bits (84), Expect = 0.009
 Identities = 34/168 (20%), Positives = 77/168 (45%), Gaps = 16/168 (9%)

Query: 7    LEHYLDSIENLPFELQRNFQLM-----RDL---DQRTEDLKAEIDKLATEYMSSARSLSS 58
            LE  L + E+    L+ N Q +     RDL   D++ E+ + ++ +   EY +       
Sbjct: 1551 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1610

Query: 59   EEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIES 118
            +  LA   + ++  G  K+  + +   A++  E   K +R+L   +  F+ +L++ +   
Sbjct: 1611 QRALAAAAK-KKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1668

Query: 119  SDYDSSSSKGKKKGRT------QKEKKAARARSKGKNSDEEAPKTAQK 160
             +  +++ + +KK ++      Q ++  A A    K +D E  + A++
Sbjct: 1669 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1716



 Score = 33.5 bits (75), Expect = 0.100
 Identities = 32/141 (22%), Positives = 62/141 (43%), Gaps = 20/141 (14%)

Query: 28   MRDLDQRTEDLKAEIDKL---ATEYMSSARSLSSE-----EKLALLKQIQEAYGKCKEFG 79
            M+D  +  ED +A  D++   A E    A+SL ++     E LA  ++ ++     KE  
Sbjct: 1654 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1713

Query: 80   DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKK 139
             +++  ++     +    RRL+  +A+ E +L+E+Q            G  +  + + +K
Sbjct: 1714 AEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQ------------GNMEAMSDRVRK 1761

Query: 140  AARARSKGKNSDEEAPKTAQK 160
            A +   +  N       TAQK
Sbjct: 1762 ATQQAEQLSNELATERSTAQK 1782



 Score = 28.9 bits (63), Expect = 2.5
 Identities = 36/171 (21%), Positives = 73/171 (42%), Gaps = 14/171 (8%)

Query: 8    EHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEK--LALL 65
            + +   IENL  + +        L++    L+ E+D L  +  +  + +S+ EK      
Sbjct: 1395 KRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD 1454

Query: 66   KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHI---RRLDTDL-ARFEADLKEKQIESSDY 121
            + + E      ++ D++ +   +  E   K +   R L+  L A+ E +   K +++   
Sbjct: 1455 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1514

Query: 122  DSSSSK---GKKKGRTQKEKKAARA-----RSKGKNSDEEAPKTAQKKLKL 164
            D  SSK   GK     +K K+A        +++ +  ++E   T   KL+L
Sbjct: 1515 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1565



 Score = 28.1 bits (61), Expect = 4.2
 Identities = 29/155 (18%), Positives = 63/155 (40%), Gaps = 8/155 (5%)

Query: 28   MRDLDQRTEDLKAEIDKLATEYMSSARSLS--------SEEKLALLKQIQEAYGKCKEFG 79
            +R L++    L+ ++D+      +  R +S        S++KL       EA  + K+  
Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1397

Query: 80   DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKK 139
              +++   Q YE       +L+    R + +L +  ++  +     S  +KK R   +  
Sbjct: 1398 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 1457

Query: 140  AARARSKGKNSDEEAPKTAQKKLKLVRTVPLSGSI 174
            A       K +DE     A+ + K  + + L+ ++
Sbjct: 1458 AEEKNISSKYADERDRAEAEAREKETKALSLARAL 1492


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 36.6 bits (83), Expect = 0.012
 Identities = 33/144 (22%), Positives = 71/144 (49%), Gaps = 20/144 (13%)

Query: 33   QRTEDLKAEIDKLATEYMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQT--- 89
            Q  +DL+AE DK+ T          ++ K+ L +Q+ +  G  ++  + KV++ ++    
Sbjct: 1005 QALDDLQAEEDKVNT---------LTKAKVKLEQQVDDLEGSLEQ--EKKVRMDLERAKR 1053

Query: 90   -----YEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKG-RTQKEKKAARA 143
                  ++  + I  L+ D  + +  LK+K  E +  ++     +  G + QK+ K  +A
Sbjct: 1054 KLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQA 1113

Query: 144  RSKGKNSDEEAPKTAQKKLKLVRT 167
            R +    + EA +TA+ K++ +R+
Sbjct: 1114 RIEELEEELEAERTARAKVEKLRS 1137



 Score = 29.3 bits (64), Expect = 1.9
 Identities = 33/167 (19%), Positives = 70/167 (41%), Gaps = 21/167 (12%)

Query: 11   LDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALLKQIQE 70
            LD       +L+ N  ++   ++R   L+AE+++L      + RS     KLA  + I+ 
Sbjct: 1657 LDDAVRANDDLKENIAIV---ERRNNLLQAELEELRAVVEQTERS----RKLAEQELIET 1709

Query: 71   AYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSK--- 127
            +         ++VQL       +    +++D DL++ + +++E   E  + +  + K   
Sbjct: 1710 S---------ERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAIT 1760

Query: 128  --GKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSG 172
                     +KE+  +    + K + E+  K  Q +L     + L G
Sbjct: 1761 DAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKG 1807



 Score = 27.7 bits (60), Expect = 5.5
 Identities = 37/169 (21%), Positives = 69/169 (40%), Gaps = 17/169 (10%)

Query: 2    AAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEK 61
            AA +  +H  DS+  L  ++    ++ + L++   + K E+D + +      ++ ++ EK
Sbjct: 1189 AAALRKKH-ADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEK 1247

Query: 62   L--ALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESS 119
            +   L  Q+ E   K +E       L  Q          +L T+       L EK+    
Sbjct: 1248 MCRTLEDQMNEHRSKAEETQRSVNDLTSQR--------AKLQTENGELSRQLDEKEA--- 1296

Query: 120  DYDSSSSKGKKKGRTQKE--KKAARARSKGKNSDEEAPKTAQKKLKLVR 166
               S  ++GK     Q E  K+      K KN+   A ++A+    L+R
Sbjct: 1297 -LISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLR 1344


>gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo
           sapiens]
          Length = 1002

 Score = 36.6 bits (83), Expect = 0.012
 Identities = 26/111 (23%), Positives = 53/111 (47%), Gaps = 5/111 (4%)

Query: 11  LDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKL-----ALL 65
           L++++N    + R     R+L ++  +L++   KL  E M    +L SE+ +       L
Sbjct: 525 LETMQNDRTTISRALSQNRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKRELGKKL 584

Query: 66  KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQI 116
            ++QE   + KE  + K Q A    +  D+++  L   +A ++    EK++
Sbjct: 585 GELQEKLSELKETVELKSQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEV 635


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.339 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,703,763
Number of Sequences: 37866
Number of extensions: 222376
Number of successful extensions: 3078
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 133
Number of HSP's successfully gapped in prelim test: 274
Number of HSP's that attempted gapping in prelim test: 2216
Number of HSP's gapped (non-prelim): 991
length of query: 179
length of database: 18,247,518
effective HSP length: 96
effective length of query: 83
effective length of database: 14,612,382
effective search space: 1212827706
effective search space used: 1212827706
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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