Search of human proteins with 189083821

Search of human proteins with 189083821

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189083821 inhibitor of growth family, member 4 isoform 9
[Homo sapiens]
         (249 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189083821 inhibitor of growth family, member 4 isoform 9 [Hom...   510   e-145
gi|38201670 inhibitor of growth family, member 4 isoform 1 [Homo...   501   e-142
gi|189083826 inhibitor of growth family, member 4 isoform 3 [Hom...   497   e-141
gi|189083828 inhibitor of growth family, member 4 isoform 4 [Hom...   496   e-141
gi|189083830 inhibitor of growth family, member 4 isoform 5 [Hom...   448   e-126
gi|18644730 inhibitor of growth family, member 5 [Homo sapiens]       354   3e-98
gi|189083832 inhibitor of growth family, member 4 isoform 6 [Hom...   327   5e-90
gi|38201667 inhibitor of growth family, member 1 isoform A [Homo...   191   5e-49
gi|4504695 inhibitor of growth family, member 2 [Homo sapiens]        169   3e-42
gi|38201663 inhibitor of growth family, member 1 isoform C [Homo...   150   1e-36
gi|38201661 inhibitor of growth family, member 1 isoform D [Homo...   150   1e-36
gi|38201665 inhibitor of growth family, member 1 isoform B [Homo...   146   1e-35
gi|38201655 inhibitor of growth family, member 3 isoform 1 [Homo...   115   3e-26
gi|38201659 inhibitor of growth family, member 3 isoform 3 [Homo...    60   1e-09
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho...    50   2e-06
gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo ...    48   7e-06
gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo ...    48   7e-06
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    47   2e-05
gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens]       45   8e-05
gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]       45   8e-05
gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]      42   5e-04
gi|35493853 otoferlin isoform c [Homo sapiens]                         41   9e-04
gi|35493868 otoferlin isoform b [Homo sapiens]                         41   9e-04
gi|35493860 otoferlin isoform d [Homo sapiens]                         41   9e-04
gi|34740331 otoferlin isoform a [Homo sapiens]                         41   9e-04
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]                41   0.001
gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo ...    41   0.001
gi|55770834 centromere protein F [Homo sapiens]                        40   0.002
gi|57546899 myeloid/lymphoid or mixed-lineage leukemia transloca...    40   0.002
gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocat...    40   0.002

>gi|189083821 inhibitor of growth family, member 4 isoform 9 [Homo
           sapiens]
          Length = 249

 Score =  510 bits (1314), Expect = e-145
 Identities = 249/249 (100%), Positives = 249/249 (100%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE
Sbjct: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120

Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 180
           YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS
Sbjct: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 180

Query: 181 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 240
           VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP
Sbjct: 181 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 240

Query: 241 RCSQERKKK 249
           RCSQERKKK
Sbjct: 241 RCSQERKKK 249


>gi|38201670 inhibitor of growth family, member 4 isoform 1 [Homo
           sapiens]
          Length = 248

 Score =  501 bits (1291), Expect = e-142
 Identities = 247/249 (99%), Positives = 247/249 (99%), Gaps = 1/249 (0%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE
Sbjct: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120

Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 180
           YDSSSSKGKK  RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS
Sbjct: 121 YDSSSSKGKKS-RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 179

Query: 181 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 240
           VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP
Sbjct: 180 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 239

Query: 241 RCSQERKKK 249
           RCSQERKKK
Sbjct: 240 RCSQERKKK 248


>gi|189083826 inhibitor of growth family, member 4 isoform 3 [Homo
           sapiens]
          Length = 246

 Score =  497 bits (1280), Expect = e-141
 Identities = 245/249 (98%), Positives = 246/249 (98%), Gaps = 3/249 (1%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE
Sbjct: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120

Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 180
           YDSSSSK   +GRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS
Sbjct: 121 YDSSSSK---EGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 177

Query: 181 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 240
           VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP
Sbjct: 178 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 237

Query: 241 RCSQERKKK 249
           RCSQERKKK
Sbjct: 238 RCSQERKKK 246


>gi|189083828 inhibitor of growth family, member 4 isoform 4 [Homo
           sapiens]
          Length = 245

 Score =  496 bits (1278), Expect = e-141
 Identities = 245/249 (98%), Positives = 245/249 (98%), Gaps = 4/249 (1%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE
Sbjct: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120

Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 180
           YDSSSSKG    RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS
Sbjct: 121 YDSSSSKG----RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 176

Query: 181 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 240
           VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP
Sbjct: 177 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 236

Query: 241 RCSQERKKK 249
           RCSQERKKK
Sbjct: 237 RCSQERKKK 245


>gi|189083830 inhibitor of growth family, member 4 isoform 5 [Homo
           sapiens]
          Length = 225

 Score =  448 bits (1152), Expect = e-126
 Identities = 224/249 (89%), Positives = 225/249 (90%), Gaps = 24/249 (9%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MAAGMYLEHYLD+                        LKAEIDKLATEYMSSARSLSSEE
Sbjct: 1   MAAGMYLEHYLDN------------------------LKAEIDKLATEYMSSARSLSSEE 36

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 37  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 96

Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 180
           YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS
Sbjct: 97  YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 156

Query: 181 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 240
           VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP
Sbjct: 157 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 216

Query: 241 RCSQERKKK 249
           RCSQERKKK
Sbjct: 217 RCSQERKKK 225


>gi|18644730 inhibitor of growth family, member 5 [Homo sapiens]
          Length = 240

 Score =  354 bits (909), Expect = 3e-98
 Identities = 174/249 (69%), Positives = 203/249 (81%), Gaps = 10/249 (4%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MA  MYLEHYLDSIENLP ELQRNFQLMR+LDQRTED KAEID LA EY+S+ ++LS ++
Sbjct: 1   MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQ 60

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           ++  L++IQ AY KCKE+ DDKVQLAMQTYEMVDKHIRRLD DLARFEADLK+K +E SD
Sbjct: 61  RVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MEGSD 119

Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 180
           ++SS  +G KKGR QKEK+ +R R + + S+E+ PK  + K        E+   + T  S
Sbjct: 120 FESSGGRGLKKGRGQKEKRGSRGRGR-RTSEEDTPKKKKHK-----GGSEF---TDTILS 170

Query: 181 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 240
           VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDC IEWFHFACV LTTKP+GKWFCP
Sbjct: 171 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCP 230

Query: 241 RCSQERKKK 249
           RC QE++KK
Sbjct: 231 RCVQEKRKK 239


>gi|189083832 inhibitor of growth family, member 4 isoform 6 [Homo
           sapiens]
          Length = 179

 Score =  327 bits (839), Expect = 5e-90
 Identities = 169/172 (98%), Positives = 169/172 (98%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE
Sbjct: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120

Query: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYG 172
           YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRT P  G
Sbjct: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSG 172


>gi|38201667 inhibitor of growth family, member 1 isoform A [Homo
           sapiens]
          Length = 279

 Score =  191 bits (485), Expect = 5e-49
 Identities = 99/253 (39%), Positives = 148/253 (58%), Gaps = 15/253 (5%)

Query: 6   YLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALL 65
           Y+E YLDSIE+LPF+LQRN  LMR++D + +++  E+D+    Y   +R     +K  +L
Sbjct: 15  YVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDEC---YERFSRETDGAQKRRML 71

Query: 66  KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEA--DLKEKQIESSDYDS 123
             +Q A  + +E GD+K+Q+  Q  E+V+   R++D+ +  FEA  +L +    S    +
Sbjct: 72  HCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGA 131

Query: 124 SSSKGKKKGRTQK--EKKAARARSK------GKNSDEEAPKTAQKKLKLVRTSPEYGMPS 175
              KG+   +  K   K++ R R+         N D +   +   K K  +TS +     
Sbjct: 132 DRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKRSK 191

Query: 176 VTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRG 235
               +   +   D+P+DPNEPTYCLC+QVSYGEMIGCDN +C IEWFHF+CVGL  KP+G
Sbjct: 192 AK--AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKG 249

Query: 236 KWFCPRCSQERKK 248
           KW+CP+C  E +K
Sbjct: 250 KWYCPKCRGENEK 262


>gi|4504695 inhibitor of growth family, member 2 [Homo sapiens]
          Length = 280

 Score =  169 bits (427), Expect = 3e-42
 Identities = 89/252 (35%), Positives = 141/252 (55%), Gaps = 23/252 (9%)

Query: 6   YLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALL 65
           Y++ YL+ +E+LP ++QRN  ++R+LD + ++   EID +  +Y          +K  L 
Sbjct: 27  YVQDYLECVESLPHDMQRNVSVLRELDNKYQETLKEIDDVYEKYKKED---DLNQKKRLQ 83

Query: 66  KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLK-EKQIESSDYDSS 124
           + +Q A    +E GD+K+Q+  Q  E+V+   R+++     F+   + E+  + +  DSS
Sbjct: 84  QLLQRALINSQELGDEKIQIVTQMLELVENRARQMELHSQCFQDPAESERASDKAKMDSS 143

Query: 125 ----SSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQ----KKLKLVRTSPEYGMPSV 176
               SS+  ++ RT + +      +  ++ D++ PK  +    KK K  +   E     V
Sbjct: 144 QPERSSRRPRRQRTSESRDLCHMANGIEDCDDQPPKEKKSKSAKKKKRSKAKQEREASPV 203

Query: 177 TFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGK 236
            F            +DPNEPTYCLC+QVSYGEMIGCDN  C IEWFHF+CV LT KP+GK
Sbjct: 204 EFA-----------IDPNEPTYCLCNQVSYGEMIGCDNEQCPIEWFHFSCVSLTYKPKGK 252

Query: 237 WFCPRCSQERKK 248
           W+CP+C  + +K
Sbjct: 253 WYCPKCRGDNEK 264


>gi|38201663 inhibitor of growth family, member 1 isoform C [Homo
           sapiens]
          Length = 235

 Score =  150 bits (379), Expect = 1e-36
 Identities = 78/210 (37%), Positives = 116/210 (55%), Gaps = 12/210 (5%)

Query: 49  YMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFE 108
           Y   +R     +K  +L  +Q A  + +E GD+K+Q+  Q  E+V+   R++D+ +  FE
Sbjct: 11  YERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFE 70

Query: 109 A--DLKEKQIESSDYDSSSSKGKKKGRTQK--EKKAARARSK------GKNSDEEAPKTA 158
           A  +L +    S    +   KG+   +  K   K++ R R+         N D +   + 
Sbjct: 71  AQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASG 130

Query: 159 QKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCS 218
             K K  +TS +         +   +   D+P+DPNEPTYCLC+QVSYGEMIGCDN +C 
Sbjct: 131 TPKEKKAKTSKKKKRSKAK--AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECP 188

Query: 219 IEWFHFACVGLTTKPRGKWFCPRCSQERKK 248
           IEWFHF+CVGL  KP+GKW+CP+C  E +K
Sbjct: 189 IEWFHFSCVGLNHKPKGKWYCPKCRGENEK 218


>gi|38201661 inhibitor of growth family, member 1 isoform D [Homo
           sapiens]
          Length = 422

 Score =  150 bits (379), Expect = 1e-36
 Identities = 78/210 (37%), Positives = 116/210 (55%), Gaps = 12/210 (5%)

Query: 49  YMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFE 108
           Y   +R     +K  +L  +Q A  + +E GD+K+Q+  Q  E+V+   R++D+ +  FE
Sbjct: 198 YERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFE 257

Query: 109 A--DLKEKQIESSDYDSSSSKGKKKGRTQK--EKKAARARSK------GKNSDEEAPKTA 158
           A  +L +    S    +   KG+   +  K   K++ R R+         N D +   + 
Sbjct: 258 AQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASG 317

Query: 159 QKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCS 218
             K K  +TS +         +   +   D+P+DPNEPTYCLC+QVSYGEMIGCDN +C 
Sbjct: 318 TPKEKKAKTSKKKKRSKAK--AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECP 375

Query: 219 IEWFHFACVGLTTKPRGKWFCPRCSQERKK 248
           IEWFHF+CVGL  KP+GKW+CP+C  E +K
Sbjct: 376 IEWFHFSCVGLNHKPKGKWYCPKCRGENEK 405


>gi|38201665 inhibitor of growth family, member 1 isoform B [Homo
           sapiens]
          Length = 210

 Score =  146 bits (369), Expect = 1e-35
 Identities = 75/195 (38%), Positives = 111/195 (56%), Gaps = 12/195 (6%)

Query: 64  LLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEA--DLKEKQIESSDY 121
           +L  +Q A  + +E GD+K+Q+  Q  E+V+   R++D+ +  FEA  +L +    S   
Sbjct: 1   MLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKA 60

Query: 122 DSSSSKGKKKGRTQK--EKKAARARSK------GKNSDEEAPKTAQKKLKLVRTSPEYGM 173
            +   KG+   +  K   K++ R R+         N D +   +   K K  +TS +   
Sbjct: 61  GADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKR 120

Query: 174 PSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKP 233
                 +   +   D+P+DPNEPTYCLC+QVSYGEMIGCDN +C IEWFHF+CVGL  KP
Sbjct: 121 SKAK--AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKP 178

Query: 234 RGKWFCPRCSQERKK 248
           +GKW+CP+C  E +K
Sbjct: 179 KGKWYCPKCRGENEK 193


>gi|38201655 inhibitor of growth family, member 3 isoform 1 [Homo
           sapiens]
          Length = 418

 Score =  115 bits (289), Expect = 3e-26
 Identities = 49/127 (38%), Positives = 72/127 (56%), Gaps = 3/127 (2%)

Query: 123 SSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSVH 182
           SSS+   + GR  K    + ++    +S   +  +      +V+   E    +       
Sbjct: 290 SSSAADSRSGRKSKNNNKSSSQQSSSSSSSSSLSSCSSSSTVVQ---EISQQTTVVPESD 346

Query: 183 PSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRC 242
            +  +D   DPNEP YC+C+QVSYGEM+GCDN DC IEWFH+ CVGLT  P+GKW+CP+C
Sbjct: 347 SNSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQC 406

Query: 243 SQERKKK 249
           +   K++
Sbjct: 407 TAAMKRR 413



 Score = 84.7 bits (208), Expect = 7e-17
 Identities = 39/108 (36%), Positives = 71/108 (65%)

Query: 5   MYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLAL 64
           +YLE YL+ IE LP +L+  F  MR++D + ++   ++++  +E+  +A+    E +   
Sbjct: 2   LYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREEQ 61

Query: 65  LKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLK 112
           +  I++ Y K  E  D+KVQLA Q Y++VD+H+R+LD +LA+F+ +L+
Sbjct: 62  MASIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELE 109


>gi|38201659 inhibitor of growth family, member 3 isoform 3 [Homo
          sapiens]
          Length = 92

 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 29/88 (32%), Positives = 53/88 (60%)

Query: 5  MYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLAL 64
          +YLE YL+ IE LP +L+  F  MR++D + ++   ++++  +E+  +A+    E +   
Sbjct: 2  LYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREEQ 61

Query: 65 LKQIQEAYGKCKEFGDDKVQLAMQTYEM 92
          +  I++ Y K  E  D+KVQLA Q Y++
Sbjct: 62 MASIKKDYYKALEDADEKVQLANQIYDL 89


>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
           sapiens]
          Length = 929

 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 20/43 (46%), Positives = 30/43 (69%), Gaps = 5/43 (11%)

Query: 209 MIGCDNPDCSIEWFHFACVGLTTKP--RGKWFCPRCSQERKKK 249
           MIGCD+ D   +W+H+ CVG+ T P    +WFCP+C+ ++K K
Sbjct: 880 MIGCDDCD---DWYHWPCVGIMTAPPEEMQWFCPKCANKKKDK 919



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 19/73 (26%), Positives = 36/73 (49%), Gaps = 2/73 (2%)

Query: 107 FEADLKEKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKL-- 164
           FE   K K+ E         K K+K + +KEK+  + + + +  ++E  K   +K+K+  
Sbjct: 690 FEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKIKVEP 749

Query: 165 VRTSPEYGMPSVT 177
           V  +P   +P +T
Sbjct: 750 VALAPSPVIPRLT 762


>gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo
           sapiens]
          Length = 1188

 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 24/156 (15%)

Query: 104 LARFEADLKEKQIESSDYDS-SSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKL 162
           LA  E   +++ +E  D  + S   G  +   QK K  +   S   +S ++   +  KK 
Sbjct: 6   LAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTSPIKKK 65

Query: 163 KL-------------VRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYC-LCHQVSYGE 208
           K              +R  P Y M      +  P DV+  P D     YC +CH+   G+
Sbjct: 66  KKPGLLNSNNKEQSELRHGPFYYMKQPL--TTDPVDVV--PQDGRNDFYCWVCHRE--GQ 119

Query: 209 MIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQ 244
           ++ C+        +H  C+ LT++P G WFCP C +
Sbjct: 120 VLCCE---LCPRVYHAKCLRLTSEPEGDWFCPECEK 152


>gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo
           sapiens]
          Length = 1160

 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 24/156 (15%)

Query: 104 LARFEADLKEKQIESSDYDS-SSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKL 162
           LA  E   +++ +E  D  + S   G  +   QK K  +   S   +S ++   +  KK 
Sbjct: 6   LAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTSPIKKK 65

Query: 163 KL-------------VRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYC-LCHQVSYGE 208
           K              +R  P Y M      +  P DV+  P D     YC +CH+   G+
Sbjct: 66  KKPGLLNSNNKEQSELRHGPFYYMKQPL--TTDPVDVV--PQDGRNDFYCWVCHRE--GQ 119

Query: 209 MIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQ 244
           ++ C+        +H  C+ LT++P G WFCP C +
Sbjct: 120 VLCCE---LCPRVYHAKCLRLTSEPEGDWFCPECEK 152


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 45/172 (26%), Positives = 79/172 (45%), Gaps = 13/172 (7%)

Query: 1    MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
            M A +  +H  DS+  L  ++    ++ + L++   + K EID L++   S ++S ++ E
Sbjct: 1189 MVAALRKKH-ADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLE 1247

Query: 61   KL--ALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIES 118
            K+   L  Q+ EA GK +E      +L  Q          RL T+       L+EK  ES
Sbjct: 1248 KICRTLEDQLSEARGKNEEIQRSLSELTTQK--------SRLQTEAGELSRQLEEK--ES 1297

Query: 119  SDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPE 170
                 S SK     +T++ K+     +K KN+   A ++++    L+R   E
Sbjct: 1298 IVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYE 1349


>gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens]
          Length = 660

 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 7/59 (11%)

Query: 194 NEPTYCLCHQVSYG-EMIGCDNPDCSIEWFHFACVGLT---TKPRGKWFCPRCSQERKK 248
           N P YC+C +      MIGCDN  C+ EWFH  C+ +T    K   +W+C  C ++  K
Sbjct: 24  NAPIYCICRKPDINCFMIGCDN--CN-EWFHGDCIRITEKMAKAIREWYCRECREKDPK 79


>gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]
          Length = 656

 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 7/59 (11%)

Query: 194 NEPTYCLCHQVSYG-EMIGCDNPDCSIEWFHFACVGLT---TKPRGKWFCPRCSQERKK 248
           N P YC+C +      MIGCDN  C+ EWFH  C+ +T    K   +W+C  C ++  K
Sbjct: 24  NAPIYCICRKPDINCFMIGCDN--CN-EWFHGDCIRITEKMAKAIREWYCRECREKDPK 79


>gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]
          Length = 1544

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 9/133 (6%)

Query: 113  EKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYG 172
            ++++E     S   +  KK RT K+KK   +  K  N+ +      ++  +LVR++  + 
Sbjct: 1411 KRRLEREGLSSERWERVKKMRTPKKKKIKLSHPKDMNNFK---LERERSYELVRSAETHS 1467

Query: 173  MPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTK 232
            +PS T  S       +  + P     CL  +    + + CD   C+ +WFH  CVG++ +
Sbjct: 1468 LPSDTSYSEQEDSEDEDAICP--AVSCLQPEGDEVDWVQCDG-SCN-QWFHQVCVGVSPE 1523

Query: 233  PRGK--WFCPRCS 243
               K  + C RC+
Sbjct: 1524 MAEKEDYICVRCT 1536



 Score = 33.1 bits (74), Expect = 0.23
 Identities = 17/60 (28%), Positives = 27/60 (45%), Gaps = 5/60 (8%)

Query: 190  PVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGK--WFCPRCSQERK 247
            P+   +   CLC +     MI C+      + FH +CV + +  +G   W CP C +  K
Sbjct: 1170 PLQDVDIKICLCQKAPAAPMIQCE---LCRDAFHTSCVAVPSISQGLRIWLCPHCRRSEK 1226


>gi|35493853 otoferlin isoform c [Homo sapiens]
          Length = 1307

 Score = 41.2 bits (95), Expect = 9e-04
 Identities = 20/62 (32%), Positives = 37/62 (59%), Gaps = 1/62 (1%)

Query: 110 DLKEKQ-IESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTS 168
           DL+EK+ +++++    S KGK+K R  KE+K  + +S G     EAP+  + K+  ++  
Sbjct: 662 DLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVY 721

Query: 169 PE 170
           P+
Sbjct: 722 PK 723


>gi|35493868 otoferlin isoform b [Homo sapiens]
          Length = 1230

 Score = 41.2 bits (95), Expect = 9e-04
 Identities = 20/62 (32%), Positives = 37/62 (59%), Gaps = 1/62 (1%)

Query: 110 DLKEKQ-IESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTS 168
           DL+EK+ +++++    S KGK+K R  KE+K  + +S G     EAP+  + K+  ++  
Sbjct: 585 DLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVY 644

Query: 169 PE 170
           P+
Sbjct: 645 PK 646


>gi|35493860 otoferlin isoform d [Homo sapiens]
          Length = 1230

 Score = 41.2 bits (95), Expect = 9e-04
 Identities = 20/62 (32%), Positives = 37/62 (59%), Gaps = 1/62 (1%)

Query: 110 DLKEKQ-IESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTS 168
           DL+EK+ +++++    S KGK+K R  KE+K  + +S G     EAP+  + K+  ++  
Sbjct: 585 DLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVY 644

Query: 169 PE 170
           P+
Sbjct: 645 PK 646


>gi|34740331 otoferlin isoform a [Homo sapiens]
          Length = 1997

 Score = 41.2 bits (95), Expect = 9e-04
 Identities = 20/62 (32%), Positives = 37/62 (59%), Gaps = 1/62 (1%)

Query: 110  DLKEKQ-IESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTS 168
            DL+EK+ +++++    S KGK+K R  KE+K  + +S G     EAP+  + K+  ++  
Sbjct: 1352 DLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVY 1411

Query: 169  PE 170
            P+
Sbjct: 1412 PK 1413


>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
          Length = 1437

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 16/34 (47%), Positives = 21/34 (61%), Gaps = 1/34 (2%)

Query: 207  GEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 240
            GE++ CD  DC  + +H  C+ LT  P GKW CP
Sbjct: 1331 GELVMCDKKDCP-KAYHLLCLNLTQPPYGKWECP 1363



 Score = 32.3 bits (72), Expect = 0.40
 Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 2/46 (4%)

Query: 197 TYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRC 242
           T C   + S   +I C+   C  + FH  C+GL + P  K+ C  C
Sbjct: 702 TVCQICESSGDSLIPCEGECC--KHFHLECLGLASLPDSKFICMEC 745


>gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo
           sapiens]
          Length = 1135

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 34/143 (23%), Positives = 59/143 (41%), Gaps = 23/143 (16%)

Query: 104 LARFEADLKEKQIESSDYDS-SSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKL 162
           LA  E   +++ +E  D  + S   G  +   QK K  +   S   +S ++   +  KK 
Sbjct: 6   LAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTSPIKKK 65

Query: 163 KLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYC-LCHQVSYGEMIGCDNPDCSIEW 221
           K          P +   +       +   D     YC +CH+   G+++ C+        
Sbjct: 66  K---------KPGLLNSN-------NKEQDGRNDFYCWVCHRE--GQVLCCE---LCPRV 104

Query: 222 FHFACVGLTTKPRGKWFCPRCSQ 244
           +H  C+ LT++P G WFCP C +
Sbjct: 105 YHAKCLRLTSEPEGDWFCPECEK 127


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 49/201 (24%), Positives = 85/201 (42%), Gaps = 41/201 (20%)

Query: 12   DSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLS---------SEEKL 62
            D +ENL  ELQ + +    +    E+ KAE++ L T+    ARSL            EK 
Sbjct: 2154 DKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKE 2213

Query: 63   ALLKQIQEAYGKCKEFG----------DDKVQLAMQ-------TYEMVDKHIRRLDTDLA 105
             L KQIQE  G+  E            ++K Q  +Q         EM+   ++ L+  +A
Sbjct: 2214 NLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVA 2273

Query: 106  RFEADLK-----EKQIE---SSDYDSSSSKGKKKGRTQ-KEKKAARARSKGKNSDEEAP- 155
                D +     E+ ++     ++   +S  K + R +  EKK      + K S+  A  
Sbjct: 2274 ALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADL 2333

Query: 156  -----KTAQKKLKLVRTSPEY 171
                 +  +++L++ RT+ E+
Sbjct: 2334 LKGRVENLERELEIARTNQEH 2354


>gi|57546899 myeloid/lymphoid or mixed-lineage leukemia translocated
           to, 10 isoform b [Homo sapiens]
          Length = 1011

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 2/39 (5%)

Query: 209 MIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRC-SQER 246
           ++ CD   CS+   H AC G+   P G WFC +C SQER
Sbjct: 39  LVYCDGHGCSVA-VHQACYGIVQVPTGPWFCRKCESQER 76


>gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocated
           to, 10 isoform a [Homo sapiens]
          Length = 1027

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 2/39 (5%)

Query: 209 MIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRC-SQER 246
           ++ CD   CS+   H AC G+   P G WFC +C SQER
Sbjct: 39  LVYCDGHGCSVA-VHQACYGIVQVPTGPWFCRKCESQER 76


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,356,094
Number of Sequences: 37866
Number of extensions: 424147
Number of successful extensions: 4287
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 134
Number of HSP's successfully gapped in prelim test: 333
Number of HSP's that attempted gapping in prelim test: 3300
Number of HSP's gapped (non-prelim): 1158
length of query: 249
length of database: 18,247,518
effective HSP length: 100
effective length of query: 149
effective length of database: 14,460,918
effective search space: 2154676782
effective search space used: 2154676782
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.