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Search of human proteins with 188536047
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188536047 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c1 [Homo sapiens]
(1105 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188536047 SWI/SNF-related matrix-associated actin-dependent r... 2270 0.0
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re... 1352 0.0
gi|194363725 SWI/SNF-related matrix-associated actin-dependent r... 1337 0.0
gi|21237808 SWI/SNF-related matrix-associated actin-dependent re... 1337 0.0
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 81 6e-15
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 81 6e-15
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 80 1e-14
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 78 5e-14
gi|7706501 WW domain binding protein 11 [Homo sapiens] 76 2e-13
gi|33356148 formin-like 1 [Homo sapiens] 75 4e-13
gi|11386183 WAS protein family, member 2 [Homo sapiens] 74 6e-13
gi|160707881 formin 2 [Homo sapiens] 73 2e-12
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 72 3e-12
gi|146134388 YLP motif containing 1 [Homo sapiens] 72 4e-12
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens] 70 8e-12
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 70 8e-12
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 70 8e-12
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r... 69 2e-11
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r... 69 2e-11
gi|192807318 SWI/SNF-related matrix-associated actin-dependent r... 69 2e-11
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r... 69 2e-11
gi|192807314 SWI/SNF-related matrix-associated actin-dependent r... 69 2e-11
gi|192807312 SWI/SNF-related matrix-associated actin-dependent r... 69 2e-11
gi|21071056 SWI/SNF-related matrix-associated actin-dependent re... 69 2e-11
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 69 3e-11
gi|150417989 cyclin K isoform 1 [Homo sapiens] 68 5e-11
gi|153792074 proline rich 12 [Homo sapiens] 67 7e-11
gi|56549694 enabled homolog isoform a [Homo sapiens] 67 9e-11
gi|39930375 enabled homolog isoform b [Homo sapiens] 67 9e-11
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 67 9e-11
>gi|188536047 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c1 [Homo sapiens]
Length = 1105
Score = 2270 bits (5883), Expect = 0.0
Identities = 1105/1105 (100%), Positives = 1105/1105 (100%)
Query: 1 MAAAAGGGGPGTAVGATGSGIAAAAAGLAVYRRKDGGPATKFWESPETVSQLDSVRVWLG 60
MAAAAGGGGPGTAVGATGSGIAAAAAGLAVYRRKDGGPATKFWESPETVSQLDSVRVWLG
Sbjct: 1 MAAAAGGGGPGTAVGATGSGIAAAAAGLAVYRRKDGGPATKFWESPETVSQLDSVRVWLG 60
Query: 61 KHYKKYVHADAPTNKTLAGLVVQLLQFQEDAFGKHVTNPAFTKLPAKCFMDFKAGGALCH 120
KHYKKYVHADAPTNKTLAGLVVQLLQFQEDAFGKHVTNPAFTKLPAKCFMDFKAGGALCH
Sbjct: 61 KHYKKYVHADAPTNKTLAGLVVQLLQFQEDAFGKHVTNPAFTKLPAKCFMDFKAGGALCH 120
Query: 121 ILGAAYKYKNEQGWRRFDLQNPSRMDRNVEMFMNIEKTLVQNNCLTRPNIYLIPDIDLKL 180
ILGAAYKYKNEQGWRRFDLQNPSRMDRNVEMFMNIEKTLVQNNCLTRPNIYLIPDIDLKL
Sbjct: 121 ILGAAYKYKNEQGWRRFDLQNPSRMDRNVEMFMNIEKTLVQNNCLTRPNIYLIPDIDLKL 180
Query: 181 ANKLKDIIKRHQGTFTDEKSKASHHIYPYSSSQDDEEWLRPVMRKEKQVLVHWGFYPDSY 240
ANKLKDIIKRHQGTFTDEKSKASHHIYPYSSSQDDEEWLRPVMRKEKQVLVHWGFYPDSY
Sbjct: 181 ANKLKDIIKRHQGTFTDEKSKASHHIYPYSSSQDDEEWLRPVMRKEKQVLVHWGFYPDSY 240
Query: 241 DTWVHSNDVDAEIEDPPIPEKPWKVHVKWILDTDIFNEWMNEEDYEVDENRKPVSFRQRI 300
DTWVHSNDVDAEIEDPPIPEKPWKVHVKWILDTDIFNEWMNEEDYEVDENRKPVSFRQRI
Sbjct: 241 DTWVHSNDVDAEIEDPPIPEKPWKVHVKWILDTDIFNEWMNEEDYEVDENRKPVSFRQRI 300
Query: 301 STKNEEPVRSPERRDRKASANARKRKHSPSPPPPTPTESRKKSGKKGQASLYGKRRSQKE 360
STKNEEPVRSPERRDRKASANARKRKHSPSPPPPTPTESRKKSGKKGQASLYGKRRSQKE
Sbjct: 301 STKNEEPVRSPERRDRKASANARKRKHSPSPPPPTPTESRKKSGKKGQASLYGKRRSQKE 360
Query: 361 EDEQEDLTKDMEDPTPVPNIEEVVLPKNVNLKKDSENTPVKGGTVADLDEQDEETVTAGG 420
EDEQEDLTKDMEDPTPVPNIEEVVLPKNVNLKKDSENTPVKGGTVADLDEQDEETVTAGG
Sbjct: 361 EDEQEDLTKDMEDPTPVPNIEEVVLPKNVNLKKDSENTPVKGGTVADLDEQDEETVTAGG 420
Query: 421 KEDEDPAKGDQSRSVDLGEDNVTEQTNHIIIPSYASWFDYNCIHVIERRALPEFFNGKNK 480
KEDEDPAKGDQSRSVDLGEDNVTEQTNHIIIPSYASWFDYNCIHVIERRALPEFFNGKNK
Sbjct: 421 KEDEDPAKGDQSRSVDLGEDNVTEQTNHIIIPSYASWFDYNCIHVIERRALPEFFNGKNK 480
Query: 481 SKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLTGDVCAVMRVHAFLEQWGLVNYQVD 540
SKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLTGDVCAVMRVHAFLEQWGLVNYQVD
Sbjct: 481 SKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLTGDVCAVMRVHAFLEQWGLVNYQVD 540
Query: 541 PESRPMAMGPPPTPHFNVLADTPSGLVPLHLRSPQVPAAQQMLNFPEKNKEKPVDLQNFG 600
PESRPMAMGPPPTPHFNVLADTPSGLVPLHLRSPQVPAAQQMLNFPEKNKEKPVDLQNFG
Sbjct: 541 PESRPMAMGPPPTPHFNVLADTPSGLVPLHLRSPQVPAAQQMLNFPEKNKEKPVDLQNFG 600
Query: 601 LRTDIYSKKTLAKSKGASAGREWTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILH 660
LRTDIYSKKTLAKSKGASAGREWTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILH
Sbjct: 601 LRTDIYSKKTLAKSKGASAGREWTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILH 660
Query: 661 FLRLPIEDPYLENSDASLGPLAYQPVPFSQSGNPVMSTVAFLASVVDPRVASAAAKAALE 720
FLRLPIEDPYLENSDASLGPLAYQPVPFSQSGNPVMSTVAFLASVVDPRVASAAAKAALE
Sbjct: 661 FLRLPIEDPYLENSDASLGPLAYQPVPFSQSGNPVMSTVAFLASVVDPRVASAAAKAALE 720
Query: 721 EFSRVREEVPLELVEAHVKKVQEAARASGKVDPTYGLESSCIAGTGPDEPEKLEGAEEEK 780
EFSRVREEVPLELVEAHVKKVQEAARASGKVDPTYGLESSCIAGTGPDEPEKLEGAEEEK
Sbjct: 721 EFSRVREEVPLELVEAHVKKVQEAARASGKVDPTYGLESSCIAGTGPDEPEKLEGAEEEK 780
Query: 781 MEADPDGQQPEKAENKVENETDEGDKAQDGENEKNSEKEQDSEVSEDTKSEEKETEENKE 840
MEADPDGQQPEKAENKVENETDEGDKAQDGENEKNSEKEQDSEVSEDTKSEEKETEENKE
Sbjct: 781 MEADPDGQQPEKAENKVENETDEGDKAQDGENEKNSEKEQDSEVSEDTKSEEKETEENKE 840
Query: 841 LTDTCKERESDTGKKKVEHEISEGNVATAAAAALASAATKAKHLAAVEERKIKSLVALLV 900
LTDTCKERESDTGKKKVEHEISEGNVATAAAAALASAATKAKHLAAVEERKIKSLVALLV
Sbjct: 841 LTDTCKERESDTGKKKVEHEISEGNVATAAAAALASAATKAKHLAAVEERKIKSLVALLV 900
Query: 901 ETQMKKLEIKLRHFEELETIMDREKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQ 960
ETQMKKLEIKLRHFEELETIMDREKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQ
Sbjct: 901 ETQMKKLEIKLRHFEELETIMDREKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQ 960
Query: 961 QQHGQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGP 1020
QQHGQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGP
Sbjct: 961 QQHGQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGP 1020
Query: 1021 GSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQ 1080
GSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQ
Sbjct: 1021 GSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQ 1080
Query: 1081 QPPPPPPADGVPPPPAPGPPASAAP 1105
QPPPPPPADGVPPPPAPGPPASAAP
Sbjct: 1081 QPPPPPPADGVPPPPAPGPPASAAP 1105
>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c2 isoform a [Homo sapiens]
Length = 1214
Score = 1352 bits (3500), Expect = 0.0
Identities = 702/1111 (63%), Positives = 848/1111 (76%), Gaps = 65/1111 (5%)
Query: 32 RRKDGGPATKFWESPETVSQLDSVRVWLGKHYKKYVHADAPTNKTLAGLVVQLLQFQEDA 91
R+KDGGP K++E+ +TV+Q D+VR+WLGK+YKKY+ A+ PTNK+L+ LVVQLLQFQE+
Sbjct: 4 RKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQEEV 63
Query: 92 FGKHVTNPAFTKLPAKCFMDFKAGGALCHILGAAYKYKNEQGWRRFDLQNPSRMDRNVEM 151
FGKHV+N TKLP KCF+DFKAGG+LCHIL AAYK+K++QGWRR+D QNPSRMDRNVEM
Sbjct: 64 FGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRNVEM 123
Query: 152 FMNIEKTLVQNNCLTRPNIYLIPDIDLKLANKLKDIIKRHQGTFTDEKSKASHHIYPYSS 211
FM IEK+LVQNNCL+RPNI+L P+I+ KL KLKDIIKRHQGT T++K+ ASH +YP
Sbjct: 124 FMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYPVPG 183
Query: 212 SQDDEEWLRPVMRKEKQVLVHWGFYPDSYDTWVHSNDVDAEIEDPPIPEKPWKVHVKWIL 271
+ ++EEW+RPVM+++KQVL+HWG+YPDSYDTW+ +++++A +ED P PEKP KVH KWIL
Sbjct: 184 NLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAKWIL 243
Query: 272 DTDIFNEWMNEEDYEVDENRKPVSFRQRISTKN-EEPVRSP--ERRDRKASANARKRKHS 328
DTD FNEWMNEEDYEV++++ PVS R++IS K + V SP +RRD+K N +KRK S
Sbjct: 244 DTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKK-GGNYKKRKRS 302
Query: 329 PSPPPPTPTESRKKSGKKGQASLYGKRRSQKEEDEQEDLTKDMEDPTPVPNIEEVVLPKN 388
PS P PTP E++KK+ KKG ++ Y K + E+EQEDLTKDM++P+PVPN+EEV LPK
Sbjct: 303 PS-PSPTP-EAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360
Query: 389 VNLKKDSENTPVKGGTVADLDEQDEETVTAGGKEDEDPA---KGDQSRSVDLGEDNVTEQ 445
VN KKDSE+ PVKGGT+ DLDEQ++E++ GK++++ + KG+Q+++ DL EDNVTEQ
Sbjct: 361 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420
Query: 446 TNHIIIPSYASWFDYNCIHVIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 505
T+HIIIPSYA+WFDYN +H IERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
Sbjct: 421 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480
Query: 506 LTSTACRRNLTGDVCAVMRVHAFLEQWGLVNYQVDPESRPMAMGPPPTPHFNVLADTPSG 565
LTSTACRRNL GDVCA+MRVHAFLEQWGL+NYQVD ESRP MGPPPT HF+VLADTPSG
Sbjct: 481 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540
Query: 566 LVPLHLRSP-QVPAAQQMLNFPEKNKEKPVDLQNFGLRTDIYSKKTL-AKSK-GASAGRE 622
LVPL ++P Q A+QQMLNFP+K KEKP D+QNFGLRTD+Y+KK + +KSK ASA RE
Sbjct: 541 LVPLQPKTPQQTSASQQMLNFPDKGKEKPTDMQNFGLRTDMYTKKNVPSKSKAAASATRE 600
Query: 623 WTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLENSDASLGPLA 682
WTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLE+S+ASLGPLA
Sbjct: 601 WTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLEDSEASLGPLA 660
Query: 683 YQPVPFSQSGNPVMSTVAFLASVVDPRVASAAAKAALEEFSRVREEVPLELVEAHVKKVQ 742
YQP+PFSQSGNPVMSTVAFLASVVDPRVASAAAK+ALEEFS+++EEVP LVEAHV+KV+
Sbjct: 661 YQPIPFSQSGNPVMSTVAFLASVVDPRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVE 720
Query: 743 EAARASGKVDPTYGLESSCIAGTGPDEPEKLE--GAEEEKMEAD-----PDGQQPEKAEN 795
EAA+ +GK DP +GLESS IAGT DEPE++E G +E ++E + ++P +
Sbjct: 721 EAAKVTGKADPAFGLESSGIAGTTSDEPERIEESGNDEARVEGQATDEKKEPKEPREGGG 780
Query: 796 KVENETDE---------GDKAQDGENEKNSEK-EQDSEVSEDTKSEEKETEEN--KELTD 843
+E E E +K ++G++EK SEK + D V + + E KE +E KE+ +
Sbjct: 781 AIEEEAKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVE 840
Query: 844 TCKERESDTGKKKVEHEISEGNVATAAAAALASAATKAKHLAAVEERKIKSLVALLVETQ 903
+ ER K KVE +I EGN++TAAAAALA+AA KAKHLAAVEERKIKSLVALLVETQ
Sbjct: 841 SEGER-----KTKVERDIGEGNLSTAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQ 895
Query: 904 MKKLEIKLRHFEELETIMDREKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQH 963
MKKLEIKLRHFEELETIMDRE+EALE QRQQLL +RQ FHMEQLKYAE+RARQQ QQ H
Sbjct: 896 MKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMH 955
Query: 964 GQNPQQAHQ-HSGGPGLAPLGAAGHPGMMPHQQPP----PYPLMHHQMP----------- 1007
Q Q G + P GAAG P + P P P P
Sbjct: 956 QQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQ 1015
Query: 1008 -----PPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILG 1062
P QP P PG++ PG PG P+ P + TPP M MPG + G
Sbjct: 1016 AGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS------PFPNQQTPPSM--MPGAVPG 1067
Query: 1063 PRVPLTAPNGMYPPPPQQQPPPPPPADGVPP 1093
P A N P PPPPPPA + P
Sbjct: 1068 SGHPGVAGNAPLGLPFGMPPPPPPPAPSIIP 1098
Score = 36.2 bits (82), Expect = 0.18
Identities = 41/153 (26%), Positives = 49/153 (32%), Gaps = 52/153 (33%)
Query: 974 SGGPGLAPLGAAGHPGMMPHQQPPPYPLM-----------------------HHQMP--- 1007
SG PG+A G P MP PPP P + HH +P
Sbjct: 1068 SGHPGVAGNAPLGLPFGMPPPPPPPAPSIIPFGSLADSISINLPAPPNLHGHHHHLPFAP 1127
Query: 1008 --------------PPHPPQPGQIPGPGSMM--PGQHMPGRMIPTVAA----NIHPSGSG 1047
P HP P P S+ PG P + A N+ PS S
Sbjct: 1128 GTLPPPNLPVSMANPLHPNLPATTTMPSSLPLGPGLGSAAAQSPAIVAAVQGNLLPSASP 1187
Query: 1048 PTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQ 1080
PG P P P P +P + P PP Q
Sbjct: 1188 LPDPGTPLPPD----PTAP--SPGTVTPVPPPQ 1214
Score = 33.5 bits (75), Expect = 1.1
Identities = 15/25 (60%), Positives = 17/25 (68%), Gaps = 2/25 (8%)
Query: 1079 QQQPPP--PPPADGVPPPPAPGPPA 1101
QQQPPP PP + +PP A GPPA
Sbjct: 958 QQQPPPALPPGSQPIPPTGAAGPPA 982
>gi|194363725 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c2 isoform c [Homo sapiens]
Length = 1152
Score = 1337 bits (3461), Expect = 0.0
Identities = 705/1158 (60%), Positives = 853/1158 (73%), Gaps = 105/1158 (9%)
Query: 32 RRKDGGPATKFWESPETVSQLDSVRVWLGKHYKKYVHADAPTNKTLAGLVVQLLQFQEDA 91
R+KDGGP K++E+ +TV+Q D+VR+WLGK+YKKY+ A+ PTNK+L+ LVVQLLQFQE+
Sbjct: 4 RKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQEEV 63
Query: 92 FGKHVTNPAFTKLPAKCFMDFKAGGALCHILGAAYKYKNEQGWRRFDLQNPSRMDRNVEM 151
FGKHV+N TKLP KCF+DFKAGG+LCHIL AAYK+K++QGWRR+D QNPSRMDRNVEM
Sbjct: 64 FGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRNVEM 123
Query: 152 FMNIEKTLVQNNCLTRPNIYLIPDIDLKLANKLKDIIKRHQGTFTDEKSKASHHIYPYSS 211
FM IEK+LVQNNCL+RPNI+L P+I+ KL KLKDIIKRHQGT T++K+ ASH +YP
Sbjct: 124 FMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYPVPG 183
Query: 212 SQDDEEWLRPVMRKEKQVLVHWGFYPDSYDTWVHSNDVDAEIEDPPIPEKPWKVHVKWIL 271
+ ++EEW+RPVM+++KQVL+HWG+YPDSYDTW+ +++++A +ED P PEKP KVH KWIL
Sbjct: 184 NLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAKWIL 243
Query: 272 DTDIFNEWMNEEDYEVDENRKPVSFRQRISTKN-EEPVRSPE--RRDRKASANARKRKHS 328
DTD FNEWMNEEDYEV++++ PVS R++IS K + V SP+ RRD+K N +KRK S
Sbjct: 244 DTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGG-NYKKRKRS 302
Query: 329 PSPPPPTPTESRKKSGKKGQASLYGKRRSQKEEDEQEDLTKDMEDPTPVPNIEEVVLPKN 388
PSP P TP E++KK+ KKG ++ Y K + E+EQEDLTKDM++P+PVPN+EEV LPK
Sbjct: 303 PSPSP-TP-EAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360
Query: 389 VNLKKDSENTPVKGGTVADLDEQDEETVTAGGKEDEDPA---KGDQSRSVDLGEDNVTEQ 445
VN KKDSE+ PVKGGT+ DLDEQ++E++ GK++++ + KG+Q+++ DL EDNVTEQ
Sbjct: 361 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420
Query: 446 TNHIIIPSYASWFDYNCIHVIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 505
T+HIIIPSYA+WFDYN +H IERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
Sbjct: 421 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480
Query: 506 LTSTACRRNLTGDVCAVMRVHAFLEQWGLVNYQVDPESRPMAMGPPPTPHFNVLADTPSG 565
LTSTACRRNL GDVCA+MRVHAFLEQWGL+NYQVD ESRP MGPPPT HF+VLADTPSG
Sbjct: 481 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540
Query: 566 LVPLHLRSPQ--------------------VP------------AAQQMLNFPEKNKEKP 593
LVPL ++PQ VP A+QQMLNFP+K KEKP
Sbjct: 541 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600
Query: 594 VDLQNFGLRTDIYSKKTL-AKSKGA-SAGREWTEQETLLLLEALEMYKDDWNKVSEHVGS 651
D+QNFGLRTD+Y+KK + +KSK A SA REWTEQETLLLLEALEMYKDDWNKVSEHVGS
Sbjct: 601 TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660
Query: 652 RTQDECILHFLRLPIEDPYLENSDASLGPLAYQPVPFSQSGNPVMSTVAFLASVVDPRVA 711
RTQDECILHFLRLPIEDPYLE+S+ASLGPLAYQP+PFSQSGNPVMSTVAFLASVVDPRVA
Sbjct: 661 RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720
Query: 712 SAAAKAALEEFSRVREEVPLELVEAHVKKVQEAARASGKVDPTYGLESSCIAGTGPDEPE 771
SAAAK+ALEEFS+++EEVP LVEAHV+KV+EAA+ +GK DP +GLESS IAGT DEPE
Sbjct: 721 SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780
Query: 772 KLE--GAEEEKMEAD-----PDGQQPEKAENKVENETDE---------GDKAQDGENEKN 815
++E G +E ++E + ++P + +E E E +K ++G++EK
Sbjct: 781 RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840
Query: 816 SEK-EQDSEVSEDTKSEEKETEEN--KELTDTCKERESDTGKKKVEHEISEGNVATAAAA 872
SEK + D V + + E KE +E KE+ ++ ER K KVE +I EGN++TAAAA
Sbjct: 841 SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGER-----KTKVERDIGEGNLSTAAAA 895
Query: 873 ALASAATKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREKEALEQQR 932
ALA+AA KAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDRE+EALE QR
Sbjct: 896 ALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQR 955
Query: 933 QQLLTERQNFHMEQLKYAELRARQQMEQQQHGQNPQQAHQ-HSGGPGLAPLGAAGHP--- 988
QQLL +RQ FHMEQLKYAE+RARQQ QQ H Q Q G + P GAAG P
Sbjct: 956 QQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVH 1015
Query: 989 ----------------GMMPHQQPPPYPLMH-------HQMPPPHPPQPGQI------PG 1019
G P P + Q P PQPG + PG
Sbjct: 1016 GLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPG 1075
Query: 1020 P--GSMMPGQHMPGRMIP-TVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPP 1076
P S P Q P M+P V + HP + +P + + GN+L PL P P
Sbjct: 1076 PHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPG--TPL 1133
Query: 1077 PPQQQPPPPPPADGVPPP 1094
PP P P VPPP
Sbjct: 1134 PPDPTAPSPGTVTPVPPP 1151
Score = 33.5 bits (75), Expect = 1.1
Identities = 15/25 (60%), Positives = 17/25 (68%), Gaps = 2/25 (8%)
Query: 1079 QQQPPP--PPPADGVPPPPAPGPPA 1101
QQQPPP PP + +PP A GPPA
Sbjct: 989 QQQPPPALPPGSQPIPPTGAAGPPA 1013
>gi|21237808 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c2 isoform b [Homo sapiens]
Length = 1130
Score = 1337 bits (3459), Expect = 0.0
Identities = 700/1137 (61%), Positives = 845/1137 (74%), Gaps = 85/1137 (7%)
Query: 32 RRKDGGPATKFWESPETVSQLDSVRVWLGKHYKKYVHADAPTNKTLAGLVVQLLQFQEDA 91
R+KDGGP K++E+ +TV+Q D+VR+WLGK+YKKY+ A+ PTNK+L+ LVVQLLQFQE+
Sbjct: 4 RKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQEEV 63
Query: 92 FGKHVTNPAFTKLPAKCFMDFKAGGALCHILGAAYKYKNEQGWRRFDLQNPSRMDRNVEM 151
FGKHV+N TKLP KCF+DFKAGG+LCHIL AAYK+K++QGWRR+D QNPSRMDRNVEM
Sbjct: 64 FGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRNVEM 123
Query: 152 FMNIEKTLVQNNCLTRPNIYLIPDIDLKLANKLKDIIKRHQGTFTDEKSKASHHIYPYSS 211
FM IEK+LVQNNCL+RPNI+L P+I+ KL KLKDIIKRHQGT T++K+ ASH +YP
Sbjct: 124 FMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYPVPG 183
Query: 212 SQDDEEWLRPVMRKEKQVLVHWGFYPDSYDTWVHSNDVDAEIEDPPIPEKPWKVHVKWIL 271
+ ++EEW+RPVM+++KQVL+HWG+YPDSYDTW+ +++++A +ED P PEKP KVH KWIL
Sbjct: 184 NLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAKWIL 243
Query: 272 DTDIFNEWMNEEDYEVDENRKPVSFRQRISTKN-EEPVRSPE--RRDRKASANARKRKHS 328
DTD FNEWMNEEDYEV++++ PVS R++IS K + V SP+ RRD+K N +KRK S
Sbjct: 244 DTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGG-NYKKRKRS 302
Query: 329 PSPPPPTPTESRKKSGKKGQASLYGKRRSQKEEDEQEDLTKDMEDPTPVPNIEEVVLPKN 388
PSP P TP E++KK+ KKG ++ Y K + E+EQEDLTKDM++P+PVPN+EEV LPK
Sbjct: 303 PSPSP-TP-EAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT 360
Query: 389 VNLKKDSENTPVKGGTVADLDEQDEETVTAGGKEDEDPA---KGDQSRSVDLGEDNVTEQ 445
VN KKDSE+ PVKGGT+ DLDEQ++E++ GK++++ + KG+Q+++ DL EDNVTEQ
Sbjct: 361 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ 420
Query: 446 TNHIIIPSYASWFDYNCIHVIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 505
T+HIIIPSYA+WFDYN +H IERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
Sbjct: 421 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY 480
Query: 506 LTSTACRRNLTGDVCAVMRVHAFLEQWGLVNYQVDPESRPMAMGPPPTPHFNVLADTPSG 565
LTSTACRRNL GDVCA+MRVHAFLEQWGL+NYQVD ESRP MGPPPT HF+VLADTPSG
Sbjct: 481 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG 540
Query: 566 LVPLHLRSPQ--------------------VP------------AAQQMLNFPEKNKEKP 593
LVPL ++PQ VP A+QQMLNFP+K KEKP
Sbjct: 541 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP 600
Query: 594 VDLQNFGLRTDIYSKKTL-AKSKGA-SAGREWTEQETLLLLEALEMYKDDWNKVSEHVGS 651
D+QNFGLRTD+Y+KK + +KSK A SA REWTEQETLLLLEALEMYKDDWNKVSEHVGS
Sbjct: 601 TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS 660
Query: 652 RTQDECILHFLRLPIEDPYLENSDASLGPLAYQPVPFSQSGNPVMSTVAFLASVVDPRVA 711
RTQDECILHFLRLPIEDPYLE+S+ASLGPLAYQP+PFSQSGNPVMSTVAFLASVVDPRVA
Sbjct: 661 RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA 720
Query: 712 SAAAKAALEEFSRVREEVPLELVEAHVKKVQEAARASGKVDPTYGLESSCIAGTGPDEPE 771
SAAAK+ALEEFS+++EEVP LVEAHV+KV+EAA+ +GK DP +GLESS IAGT DEPE
Sbjct: 721 SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE 780
Query: 772 KLE--GAEEEKMEADPDGQQPEKAENK-----VENETDEG---------DKAQDGENEKN 815
++E G +E ++E ++ E E + +E E E +K ++G++EK
Sbjct: 781 RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE 840
Query: 816 SEKEQ-DSEVSEDTKSEEKETEEN--KELTDTCKERESDTGKKKVEHEISEGNVATAAAA 872
SEK D V + + E KE +E KE+ ++ ER K KVE +I EGN++TAAAA
Sbjct: 841 SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGER-----KTKVERDIGEGNLSTAAAA 895
Query: 873 ALASAATKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREKEALEQQR 932
ALA+AA KAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDRE+EALE QR
Sbjct: 896 ALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQR 955
Query: 933 QQLLTERQNFHMEQLKYAELRARQQMEQQQHGQNPQQAHQ-HSGGPGLAPLGAAGHPGMM 991
QQLL +RQ FHMEQLKYAE+RARQQ QQ H Q Q G + P GAAG P +
Sbjct: 956 QQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVH 1015
Query: 992 PHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGS---GP 1048
P + P G PGS+ P + + P+G+ G
Sbjct: 1016 GLAVAPASVV---------PAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGA 1066
Query: 1049 TPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPPPPAPGPPASAAP 1105
PPG+PP GP P PN PP P GV P P PP AP
Sbjct: 1067 VPPGVPPP-----GPHGPSPFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAP 1118
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 80.9 bits (198), Expect = 6e-15
Identities = 77/269 (28%), Positives = 110/269 (40%), Gaps = 46/269 (17%)
Query: 880 KAKHLAAVEERKIKSLVALLVETQ--MKKLEIKLRHFEELETIMDREKEALEQQRQQLLT 937
K++ AA E+K+ S + E Q MKK+E FE+ + EK+AL ++QQ+ T
Sbjct: 467 KSEAKAAELEKKLDSELTARHELQVEMKKME---SDFEQKLQDLQGEKDALHSEKQQIAT 523
Query: 938 ERQNFHME--QLKYAELRARQQMEQQQHGQNPQQAHQHSGGPGL---APLGAA----GHP 988
E+Q+ E QL + +++E + A + P + AP+ A G
Sbjct: 524 EKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDS 583
Query: 989 GMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSGP 1048
G + P P PPP PP P +PG + +PG + + + P
Sbjct: 584 GTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIP 643
Query: 1049 TPPGMP---------------------PMPGN--ILGPRVPLTAPNGMYPPPP-----QQ 1080
PP +P P+PG+ I P PL G+ PPPP
Sbjct: 644 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG 703
Query: 1081 QPPPPPPADG----VPPPPAPGPPASAAP 1105
PPPPPP G PPPP PG P P
Sbjct: 704 MPPPPPPLPGGPGIPPPPPFPGGPGIPPP 732
Score = 31.6 bits (70), Expect = 4.3
Identities = 29/103 (28%), Positives = 49/103 (47%), Gaps = 9/103 (8%)
Query: 756 GLESSCIAGTGPDEPEKLEGAEEEKMEADPDGQQPEKAENKVENETDEGDKAQDGENEK- 814
GL I T ++ E E+K++++ + + E K + E+D K QD + EK
Sbjct: 454 GLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMK-KMESDFEQKLQDLQGEKD 512
Query: 815 --NSEKEQDSEVSEDTKSEEKE-----TEENKELTDTCKERES 850
+SEK+Q + +D ++E + + KEL D KE S
Sbjct: 513 ALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMAS 555
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 80.9 bits (198), Expect = 6e-15
Identities = 77/269 (28%), Positives = 110/269 (40%), Gaps = 46/269 (17%)
Query: 880 KAKHLAAVEERKIKSLVALLVETQ--MKKLEIKLRHFEELETIMDREKEALEQQRQQLLT 937
K++ AA E+K+ S + E Q MKK+E FE+ + EK+AL ++QQ+ T
Sbjct: 476 KSEAKAAELEKKLDSELTARHELQVEMKKME---SDFEQKLQDLQGEKDALHSEKQQIAT 532
Query: 938 ERQNFHME--QLKYAELRARQQMEQQQHGQNPQQAHQHSGGPGL---APLGAA----GHP 988
E+Q+ E QL + +++E + A + P + AP+ A G
Sbjct: 533 EKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDS 592
Query: 989 GMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSGP 1048
G + P P PPP PP P +PG + +PG + + + P
Sbjct: 593 GTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIP 652
Query: 1049 TPPGMP---------------------PMPGN--ILGPRVPLTAPNGMYPPPP-----QQ 1080
PP +P P+PG+ I P PL G+ PPPP
Sbjct: 653 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG 712
Query: 1081 QPPPPPPADG----VPPPPAPGPPASAAP 1105
PPPPPP G PPPP PG P P
Sbjct: 713 MPPPPPPLPGGPGIPPPPPFPGGPGIPPP 741
Score = 31.6 bits (70), Expect = 4.3
Identities = 29/103 (28%), Positives = 49/103 (47%), Gaps = 9/103 (8%)
Query: 756 GLESSCIAGTGPDEPEKLEGAEEEKMEADPDGQQPEKAENKVENETDEGDKAQDGENEK- 814
GL I T ++ E E+K++++ + + E K + E+D K QD + EK
Sbjct: 463 GLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMK-KMESDFEQKLQDLQGEKD 521
Query: 815 --NSEKEQDSEVSEDTKSEEKE-----TEENKELTDTCKERES 850
+SEK+Q + +D ++E + + KEL D KE S
Sbjct: 522 ALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMAS 564
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 79.7 bits (195), Expect = 1e-14
Identities = 52/131 (39%), Positives = 55/131 (41%), Gaps = 18/131 (13%)
Query: 988 PGMMPHQQPPPYPLMHHQMPPPHPPQ----------PGQIPGPGSMMPGQHM-PGRMIPT 1036
P P QPPP+P H Q PP PPQ PG PG GS P P PT
Sbjct: 79 PQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPT 138
Query: 1037 VAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAP--NGMYPPPPQQQPPPPPPADGVPPP 1094
A P GSGP P PP P P P +G+ PPQ PPPPPA P
Sbjct: 139 SGA---PPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPA--AVPG 193
Query: 1095 PAPGPPASAAP 1105
P PGP P
Sbjct: 194 PGPGPKQGPGP 204
Score = 53.1 bits (126), Expect = 1e-06
Identities = 45/144 (31%), Positives = 52/144 (36%), Gaps = 13/144 (9%)
Query: 975 GGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQ------IPGPGSMMPGQH 1028
GG G G G G + + PP + +Q P P PGQ IP P Q
Sbjct: 12 GGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQ 71
Query: 1029 MPGRMIPTVAANIHPSGSGPTPPGM---PPMPGNILGPRV---PLTAPN-GMYPPPPQQQ 1081
P + P H P P PP P + P V P AP G PP
Sbjct: 72 PPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSA 131
Query: 1082 PPPPPPADGVPPPPAPGPPASAAP 1105
PP PP G PP PGP + P
Sbjct: 132 PPATPPTSGAPPGSGPGPTPTPPP 155
Score = 36.6 bits (83), Expect = 0.13
Identities = 41/142 (28%), Positives = 45/142 (31%), Gaps = 38/142 (26%)
Query: 967 PQQAHQHSGGPGLAPLG----AAGHPGMMPHQQP----PPYPLMHHQMPPPHPPQPGQIP 1018
P GPG P + PG P P P P PPP PG P
Sbjct: 137 PTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGP 196
Query: 1019 GP----------GSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLT 1068
GP G MPG PG G G + PG P P + G
Sbjct: 197 GPKQGPGPGGPKGGKMPGGPKPG------------GGPGLSTPGGHPKPPHRGGGE---- 240
Query: 1069 APNG---MYPPPPQQQPPPPPP 1087
P G +PP QQ PPP
Sbjct: 241 -PRGGRQHHPPYHQQHHQGPPP 261
Score = 35.8 bits (81), Expect = 0.23
Identities = 22/48 (45%), Positives = 23/48 (47%), Gaps = 13/48 (27%)
Query: 975 GGPGLAPLGAAGHPGMMPH----------QQPPPYPLMHHQMPPPHPP 1012
GGPGL+ G GHP PH Q PPY HHQ PPP P
Sbjct: 220 GGPGLSTPG--GHP-KPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGP 264
Score = 35.0 bits (79), Expect = 0.39
Identities = 54/216 (25%), Positives = 81/216 (37%), Gaps = 30/216 (13%)
Query: 823 EVSEDTKSEEKETEENKELTDTCKERESDTGKKKVEHEISEGNVATAAAAALASAATKAK 882
E S+ KS ++ ++ +E E+ K K+E E+ + A + +
Sbjct: 489 EYSQRWKSLDEMEKQQREQV----EKNMKDAKDKLESEMEDAYHEHQANLLRQDLMRRQE 544
Query: 883 HLAAVEERKIKSLVALLVETQMKKLEIKLRHFEEL----ETIMDREKEALEQQRQQLLTE 938
L +EE L + K+ E++LR EE E +M R++E EQ R+Q
Sbjct: 545 ELRRMEE--------LHNQEMQKRKEMQLRQEEERRRREEEMMIRQREMEEQMRRQ---- 592
Query: 939 RQNFHMEQLKYAELRARQQMEQQQHGQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPP 998
+ ++ Y + R R M G SGG PLG G G + PP
Sbjct: 593 -REESYSRMGYMDPRERD-MRMGGGGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPP 650
Query: 999 Y----PLMHHQMPPPHPPQPGQIP----GPGSMMPG 1026
+M M Q G P GP M PG
Sbjct: 651 ATMSGSMMGSDMRTERFGQGGAGPVGGQGPRGMGPG 686
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 77.8 bits (190), Expect = 5e-14
Identities = 56/149 (37%), Positives = 63/149 (42%), Gaps = 17/149 (11%)
Query: 967 PQQAHQHSGGPGLAPLGAAGHPGMM-PHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMP 1025
PQ PG P G PG P PPP+P Q PP P P PGP P
Sbjct: 198 PQGGRGRGRFPGAVP-GGDRFPGPAGPGGPPPPFPA--GQTPPRPPLGPPGPPGP----P 250
Query: 1026 GQHMPGRMIPTVAANIHPSGSGPTPP--------GMPPMPGNILGPRVPLTAPNGMYPPP 1077
G PG+++P A G P PP G PP+ GP P+ PP
Sbjct: 251 GPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPP 310
Query: 1078 PQQQPPPPPPADGVPPPPAP-GPPASAAP 1105
P QQ PPPPP P PP P GPP + AP
Sbjct: 311 PPQQGPPPPPGPFPPRPPGPLGPPLTLAP 339
Score = 70.1 bits (170), Expect = 1e-11
Identities = 51/149 (34%), Positives = 55/149 (36%), Gaps = 40/149 (26%)
Query: 981 PLGAAGHPGMMPHQQPPPYPLMHHQMPP--PHPPQPGQI--------PGPGSMMPGQHM- 1029
P G G P P Q PP P + PP P PP PGQ+ P G P +
Sbjct: 220 PAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLF 279
Query: 1030 PGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQPPPP---- 1085
PG+ P G P PG P PG PPPPQQ PPPP
Sbjct: 280 PGQPFGQPPLGPLPPGPPPPVPGYGPPPG----------------PPPPQQGPPPPPGPF 323
Query: 1086 ---------PPADGVPPPPAPGPPASAAP 1105
PP PPP PGPP A P
Sbjct: 324 PPRPPGPLGPPLTLAPPPHLPGPPPGAPP 352
Score = 65.9 bits (159), Expect = 2e-10
Identities = 55/158 (34%), Positives = 60/158 (37%), Gaps = 31/158 (19%)
Query: 967 PQQAHQHSGGPGLAPLGAAGHPGMMPHQQ--PPPY--PLMHHQMPPPHPPQPGQI----- 1017
P A Q P L P G G PG P Q PPP P PPP PGQ
Sbjct: 229 PFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPP 288
Query: 1018 -----PGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPG-MPPMPGNILGPRVPLTAPN 1071
PGP +PG P P P P PPG PP P LGP + L P
Sbjct: 289 LGPLPPGPPPPVPGYGPPPGPPP-------PQQGPPPPPGPFPPRPPGPLGPPLTLAPPP 341
Query: 1072 GMYPPPPQQQPP---------PPPPADGVPPPPAPGPP 1100
+ PPP PP PPP G+P + GPP
Sbjct: 342 HLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPP 379
Score = 55.8 bits (133), Expect = 2e-07
Identities = 43/119 (36%), Positives = 52/119 (43%), Gaps = 6/119 (5%)
Query: 977 PGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPP-PHPPQPGQIPGPGSMMPGQHMPGRMIP 1035
P L P G P + P PP P+ + PP P PPQ G P PG P PG + P
Sbjct: 276 PVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPP--RPPGPLGP 333
Query: 1036 TVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPPP 1094
+ P GP PPG PP ++ P +GM P + PPP P G PPP
Sbjct: 334 PLTLAPPPHLPGP-PPGAPPPAPHVNPAFFPPPTNSGM-PTSDSRGPPPTDPY-GRPPP 389
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 75.9 bits (185), Expect = 2e-13
Identities = 81/326 (24%), Positives = 131/326 (40%), Gaps = 36/326 (11%)
Query: 790 PEKAENKVENETDEGDKAQDGENEKNSEKEQDSEVSEDTKSEEKETEENKELTDTCKERE 849
PE A+ +++ + + + +K DS DT + E++ ++ + ER+
Sbjct: 238 PELAQRGHDDDVSSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERD 297
Query: 850 SDTGKKKVEHEISEGNVATAAAAALASAATKAKHLAAVEERKIKSLVALLVETQMKKLEI 909
++ KK ++ A + K K++ +++ L A+++ +++
Sbjct: 298 NNEEKKS--------GLSVRFADMPGKSRKKKKNM-----KELTPLQAMMLRMAGQEIPE 344
Query: 910 KLRHFEELETIMDRE-KEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQHGQNPQ 968
+ R EE D + + E ++Q ++ H + A ++QQ Q +
Sbjct: 345 EGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTAS--SQQQAPPQSVPPSQI 402
Query: 969 QAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQH 1028
QA G P PLG P + P P P P P P P + PG MPG
Sbjct: 403 QAPPMPGPP---PLGPPPAPPLRPPGPPTGLP------PGPPPGAPPFLRPPG--MPGLR 451
Query: 1029 MP-GRMIPTVAANIHPSGSGP-TPPGMPP-MPGNILGPRVPLTAPNGMYPPPPQQQPPP- 1084
P R++P P G P PPG+PP P PR+P AP G+ PP P PP
Sbjct: 452 GPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPL 511
Query: 1085 -----PPPADGVPPPPAPGPPASAAP 1105
P P PP P P P +AP
Sbjct: 512 VPPLGPAPPGLFPPAPLPNPGVLSAP 537
Score = 31.2 bits (69), Expect = 5.7
Identities = 27/88 (30%), Positives = 34/88 (38%), Gaps = 20/88 (22%)
Query: 1008 PPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPL 1067
P P P I +PG P + T S GP + +P +LG VP
Sbjct: 142 PDMPHAPSNILIQDIPLPGAQPPSILKKT-------SAYGPPTRAVSILP--LLGHGVPR 192
Query: 1068 TAPNGMYPPPPQQQPPPPPPADGVPPPP 1095
PP ++PP PPP PPPP
Sbjct: 193 L--------PPGRKPPGPPPG---PPPP 209
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 74.7 bits (182), Expect = 4e-13
Identities = 78/285 (27%), Positives = 108/285 (37%), Gaps = 59/285 (20%)
Query: 848 RESDTGKKKVEHEISEGNVATAAAAALASAATKAKHLAAVEERKIKSLVALLVETQMKKL 907
R +++ K +V+ + N+ A L TK L +EE ++ VALL E
Sbjct: 363 RLTESDKLQVQIQAYLDNIFDVGAL-LEDTETKNAVLEHMEE--LQEQVALLTE------ 413
Query: 908 EIKLRHFEELETIMDREKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQHGQNP 967
++ E + I + EK+ L Q R++L T R+ F A R + +
Sbjct: 414 RLRDAENESMAKIAELEKQ-LSQARKELETLRERFSESTAMGASRRPPEPEKAPPAAPTR 472
Query: 968 QQAHQHS-------------GGPG------LAPL-------GAAGHPGMMPHQQPPPYPL 1001
A + GPG + P+ G A PG+ P P P
Sbjct: 473 PSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPTPGV-PTGSPSP--- 528
Query: 1002 MHHQMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNIL 1061
+ P P PG P P +PG P P+ P P PP PP+PG++
Sbjct: 529 ---DLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDL- 584
Query: 1062 GPRVPLTAPNGMYPPPPQQQPPPPPPADG-VPPPPAPGPPASAAP 1105
PPP PPPPP DG VPPPP P PP P
Sbjct: 585 --------------PPPPPPPPPPPGTDGPVPPPPPPPPPPPGGP 615
Score = 32.0 bits (71), Expect = 3.3
Identities = 34/111 (30%), Positives = 41/111 (36%), Gaps = 34/111 (30%)
Query: 966 NPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPP--QPGQIPGPGSM 1023
+PQ+A P AP A PG +PPP P + +PPP PP P GP
Sbjct: 553 SPQEA------PPSAPPQAPPLPGS---PEPPPAPPLPGDLPPPPPPPPPPPGTDGP--- 600
Query: 1024 MPGQHMPGRMIPTVAANIHPSGSGPTPPGMPP----MPGNILGPRVPLTAP 1070
+P P P PPG PP + LGP V P
Sbjct: 601 ----------VPP------PPPPPPPPPGGPPDALGRRDSELGPGVKAKKP 635
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 74.3 bits (181), Expect = 6e-13
Identities = 53/134 (39%), Positives = 58/134 (43%), Gaps = 20/134 (14%)
Query: 977 PGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPT 1036
P PLG+ PG P PPP P PPP PP G P P + G PG P
Sbjct: 301 PPAPPLGSP--PGPKPGFAPPPAP------PPPPPPMIGIPPPPPPV--GFGSPGTPPPP 350
Query: 1037 VAANI--HPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPPP 1094
+ HP + P PP PP P PL+ P G PPPP PPPP G PPP
Sbjct: 351 SPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPP-----PPPPPPGPPPP 405
Query: 1095 P---APGPPASAAP 1105
P A G PA P
Sbjct: 406 PFTGADGQPAIPPP 419
Score = 60.1 bits (144), Expect = 1e-08
Identities = 55/217 (25%), Positives = 88/217 (40%), Gaps = 31/217 (14%)
Query: 918 ETIMDREKEALEQQRQQLLTERQNFHMEQLKYAELRAR-QQMEQQQHGQNPQQAHQHSGG 976
E ++ K+ ++++R+ ++ N + + +++ R ++ E+ + GQ ++ + G
Sbjct: 162 EKMLQDTKDIMKEKRKHRKEKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGT 221
Query: 977 PGLAPL-----GAAGHPGMMPHQQPPPYPLMHHQMPPPH-------PPQPGQIPGPGSMM 1024
G P G+ G + PP P P PP P + P
Sbjct: 222 SGYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQ 281
Query: 1025 PGQHMPGRMIPTVAANIHPSGSGP--TPPGMPPMPGNILGPRVPLTAPN--GMYPPPPQ- 1079
G + G +V + HP + P +PPG P PG P P P G+ PPPP
Sbjct: 282 RGSGLAGPKRSSVVSPSHPPPAPPLGSPPG--PKPGFAPPPAPPPPPPPMIGIPPPPPPV 339
Query: 1080 ------QQPPPPPPA-----DGVPPPPAPGPPASAAP 1105
PPP PP+ D PPP P PPA+ P
Sbjct: 340 GFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYP 376
Score = 50.1 bits (118), Expect = 1e-05
Identities = 40/130 (30%), Positives = 46/130 (35%), Gaps = 24/130 (18%)
Query: 975 GGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMPGRMI 1034
G P P G PG P PP +P PP PP P P P
Sbjct: 331 GIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPP----------PAADYPTLPP 380
Query: 1035 PTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPPP 1094
P ++ P+G P PP PP PG P P T +G QP PPP P
Sbjct: 381 PPLS---QPTGGAPPPPPPPPPPG---PPPPPFTGADG--------QPAIPPPLSDTTKP 426
Query: 1095 PAPGPPASAA 1104
+ P S A
Sbjct: 427 KSSLPAVSDA 436
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 72.8 bits (177), Expect = 2e-12
Identities = 60/147 (40%), Positives = 68/147 (46%), Gaps = 20/147 (13%)
Query: 974 SGGPGLAPLGAAGHPGMMPHQQ---PPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMP 1030
+G P PL AG P P PPP PL +PPP PP PG P +PG +P
Sbjct: 984 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIP 1042
Query: 1031 GRMIPTVAANIHPS----GSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQP--PP 1084
P A I P G+G PP PP+PG + P PL G+ PPPP PP
Sbjct: 1043 PPP-PLPGAGIPPPPPLPGAGIPPP--PPLPGAGIPPPPPLPGA-GIPPPPPLPGAGIPP 1098
Query: 1085 PPPADGV---PPPPAPG---PPASAAP 1105
PPP GV PPPP PG PP P
Sbjct: 1099 PPPLPGVGIPPPPPLPGAGIPPPPPLP 1125
Score = 72.0 bits (175), Expect = 3e-12
Identities = 58/143 (40%), Positives = 67/143 (46%), Gaps = 17/143 (11%)
Query: 974 SGGPGLAPLGAAGHPGMMPHQQ---PPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMP 1030
+G P PL AG P P PPP PL +PPP PP PG P +PG +P
Sbjct: 962 AGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIP 1020
Query: 1031 GRMIPTVAANIHPS----GSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQ----QP 1082
P A I P G+G PP PP+PG + P PL G+ PPPP P
Sbjct: 1021 PPP-PLPGAGIPPPPPLPGAGIPPP--PPLPGAGIPPPPPLPGA-GIPPPPPLPGAGIPP 1076
Query: 1083 PPPPPADGVPPPPAPGPPASAAP 1105
PPP P G+PPPP P P A P
Sbjct: 1077 PPPLPGAGIPPPP-PLPGAGIPP 1098
Score = 72.0 bits (175), Expect = 3e-12
Identities = 57/145 (39%), Positives = 68/145 (46%), Gaps = 21/145 (14%)
Query: 974 SGGPGLAPLGAAGHPGMMPHQQ---PPPYPLMHHQMPPPHP------PQPGQIPGPGSMM 1024
+G P PL AG P P PPP PL +PPP P P P +PG G +
Sbjct: 1039 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG-IP 1097
Query: 1025 PGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQ--- 1081
P +PG IP G+G PP PP+PG + P PL G+ PPPP +
Sbjct: 1098 PPPPLPGVGIPPPPPL---PGAGIPPP--PPLPGAGIPPPPPLPGA-GIPPPPPLPRVGI 1151
Query: 1082 -PPPPPPADGVPPPPAPGPPASAAP 1105
PPPP P G+PPPP P P A P
Sbjct: 1152 PPPPPLPGAGIPPPP-PLPGAGIPP 1175
Score = 71.2 bits (173), Expect = 5e-12
Identities = 58/149 (38%), Positives = 67/149 (44%), Gaps = 23/149 (15%)
Query: 974 SGGPGLAPLGAAGHPGMMPHQQ---PPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMP 1030
+G P PL AG P P PPP PL +PPP PP PG P +PG +P
Sbjct: 1017 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIP 1075
Query: 1031 GRMIPTVAANIHPS----GSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQ----QP 1082
P A I P G+G PP PP+PG + P PL G+ PPPP P
Sbjct: 1076 PPP-PLPGAGIPPPPPLPGAGIPPP--PPLPGVGIPPPPPLPGA-GIPPPPPLPGAGIPP 1131
Query: 1083 PPPPPADGVPPPP-------APGPPASAA 1104
PPP P G+PPPP P PP A
Sbjct: 1132 PPPLPGAGIPPPPPLPRVGIPPPPPLPGA 1160
Score = 70.9 bits (172), Expect = 6e-12
Identities = 54/140 (38%), Positives = 65/140 (46%), Gaps = 23/140 (16%)
Query: 976 GPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHP------PQPGQIPGPGSMMPGQHM 1029
G G+ PL G+ PPP PL +PPP P P P +PG G + P +
Sbjct: 928 GAGILPLPPLPGAGI-----PPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAG-IPPPPPL 981
Query: 1030 PGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQ----QPPPP 1085
PG IP G+G PP PP+PG + P PL G+ PPPP PPPP
Sbjct: 982 PGAGIPPPPPL---PGAGIPPP--PPLPGAGIPPPPPLPGA-GIPPPPPLPGAGIPPPPP 1035
Query: 1086 PPADGVPPPPAPGPPASAAP 1105
P G+PPPP P P A P
Sbjct: 1036 LPGAGIPPPP-PLPGAGIPP 1054
Score = 69.3 bits (168), Expect = 2e-11
Identities = 59/155 (38%), Positives = 70/155 (45%), Gaps = 27/155 (17%)
Query: 974 SGGPGLAPLGAAGHPGMMPHQQ---PPPYPLMHHQMPPPHP------PQPGQIPGPGSMM 1024
+G P PL AG P P PPP PL +PPP P P P +PG G +
Sbjct: 1083 AGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG-IP 1141
Query: 1025 PGQHMPGRMIPTV----AANIHPS----GSGPTPPGMPPMPGNILGPRVPLTAPNGMYPP 1076
P +P IP A I P G+G PP PP+PG + P PL G+ PP
Sbjct: 1142 PPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPP--PPLPGVGIPPPPPLPGV-GIPPP 1198
Query: 1077 PPQQ----QPPPPPPADGVPPPPAP--GPPASAAP 1105
PP PPPP P G+PP PAP PP + P
Sbjct: 1199 PPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIP 1233
Score = 67.8 bits (164), Expect = 5e-11
Identities = 57/149 (38%), Positives = 65/149 (43%), Gaps = 24/149 (16%)
Query: 974 SGGPGLAPLGAAGHPGMMPHQQ---PPPYPLMHHQMPPPHP------PQPGQIPGPGSMM 1024
+G P PL AG P P PPP PL +PPP P P P +PG G +
Sbjct: 1061 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAG-IP 1119
Query: 1025 PGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQP-- 1082
P +PG IP P G P PP+P + P PL G+ PPPP
Sbjct: 1120 PPPPLPGAGIPPP-----PPLPGAGIPPPPPLPRVGIPPPPPLPGA-GIPPPPPLPGAGI 1173
Query: 1083 PPPPPADGV---PPPPAPG---PPASAAP 1105
PPPPP GV PPPP PG PP P
Sbjct: 1174 PPPPPLPGVGIPPPPPLPGVGIPPPPPLP 1202
Score = 67.0 bits (162), Expect = 9e-11
Identities = 55/148 (37%), Positives = 65/148 (43%), Gaps = 27/148 (18%)
Query: 976 GPGLAPLGAAGHPGM----MPHQQ-PPPYPLMHHQM-PPPHPPQPGQ-------IPGPGS 1022
G G+ P PGM +P P P PL +M PPP PP PG +PG G
Sbjct: 872 GLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAG- 930
Query: 1023 MMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQ-- 1080
++P +PG IP P G P PP+PG G +P P PPPP
Sbjct: 931 ILPLPPLPGAGIPPP-----PPLPGAAIPPPPPLPG--AGIPLPPPLPGAGIPPPPPLPG 983
Query: 1081 ---QPPPPPPADGVPPPPAPGPPASAAP 1105
PPPP P G+PPPP P P A P
Sbjct: 984 AGIPPPPPLPGAGIPPPP-PLPGAGIPP 1010
Score = 66.6 bits (161), Expect = 1e-10
Identities = 50/129 (38%), Positives = 59/129 (45%), Gaps = 25/129 (19%)
Query: 996 PPPYPLMHHQMPPPHPPQPGQ-------IPGPGSMMPGQHMPGRMIPTVAANIHPSGSGP 1048
PPP PL +PPP PP PG +PG G + P +PG IP P P
Sbjct: 910 PPPPPLPGAGIPPP-PPLPGAGILPLPPLPGAG-IPPPPPLPGAAIPPPPPL--PGAGIP 965
Query: 1049 TPPGMP--------PMPGNILGPRVPLTAPNGMYPPPPQQ----QPPPPPPADGVPPPPA 1096
PP +P P+PG + P PL G+ PPPP PPPP P G+PPPP
Sbjct: 966 LPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPPPP- 1023
Query: 1097 PGPPASAAP 1105
P P A P
Sbjct: 1024 PLPGAGIPP 1032
Score = 62.4 bits (150), Expect = 2e-09
Identities = 51/140 (36%), Positives = 58/140 (41%), Gaps = 15/140 (10%)
Query: 975 GGPGLAPLGAAGHPGMMPHQQ---PPPYPLMHHQMPPPHP------PQPGQIPGPGSMMP 1025
G P PL AG P P PPP PL +PPP P P P +PG G + P
Sbjct: 1106 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAG-IPP 1164
Query: 1026 GQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQPPPP 1085
+PG IP G G PP PP+PG + P PL PPP PP
Sbjct: 1165 PPPLPGAGIPPPPPL---PGVGIPPP--PPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPP 1219
Query: 1086 PPADGVPPPPAPGPPASAAP 1105
PA +PPP PP P
Sbjct: 1220 APAPPLPPPGTGIPPPPLLP 1239
Score = 59.3 bits (142), Expect = 2e-08
Identities = 89/361 (24%), Positives = 130/361 (36%), Gaps = 59/361 (16%)
Query: 767 PDEPEKLEGAEEEKMEADPDGQQPEKAENKVENETDEGDKAQDGENEKNSEKEQDSEVSE 826
PDE +LE AE E A + P+K + V+ E D +G+ + EQ E
Sbjct: 632 PDEEHRLEDAETESQSAV--SETPQKRSDAVQKEVV--DMKSEGQATVIQQLEQ---TIE 684
Query: 827 DTKSEEKETEENKELTDTCKERESDTGKKKVEHEISEGNVATAAAAALASAATKAKHLAA 886
D +++ E E DT E +G + +E+ ++ A +A L
Sbjct: 685 DLRTKIAELERQYPALDT----EVASGHQGLENGVT----------ASGDVCLEALRLEE 730
Query: 887 VEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREKEALEQQRQQLLTERQNFHMEQ 946
E R + L A ++T + E + ++ + R + + Q +
Sbjct: 731 KEVRHHRILEAKSIQTSPTE-EGGVLTLPPVDGLPGRPPCPPGAE-----SGPQTKFCSE 784
Query: 947 LKYAELRARQQMEQQQHGQNPQQAHQHSGGPGLAPLGAAGHPGMMP-HQQPPPYPLMHHQ 1005
+ R ++ H Q Q Q P L G PG P H + H
Sbjct: 785 ISLIVSPRRISVQLDSH-QPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEH 843
Query: 1006 M-------------PPPHPPQPGQIPGPGSMM---PGQHMPGRMIPTVAANIHPSGSGPT 1049
PPP P PG M P +PG +PT+ PS + P
Sbjct: 844 SVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTL-----PSTAIPQ 898
Query: 1050 PPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQ-----PPPPPPADGVPPPPAPGPPASAA 1104
PP P+ G + P P P PPPP P PP P G+PPPP P P A+
Sbjct: 899 PP---PLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPP-PLPGAAIP 954
Query: 1105 P 1105
P
Sbjct: 955 P 955
Score = 57.8 bits (138), Expect = 6e-08
Identities = 51/143 (35%), Positives = 58/143 (40%), Gaps = 12/143 (8%)
Query: 974 SGGPGLAPLGAAGHPGMMPHQQ---PPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMP 1030
+G P PL AG P P PPP PL +PPP PP PG P +PG +P
Sbjct: 1116 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPP-PPLPGAGIPPPPPLPGAGIP 1174
Query: 1031 GRM-IPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLT------APNGMYPPPPQQQPP 1083
+P V P G P PP+PG + P PL AP PPP PP
Sbjct: 1175 PPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPP 1234
Query: 1084 PPP-PADGVPPPPAPGPPASAAP 1105
PP P G P P G P
Sbjct: 1235 PPLLPVSGPPLLPQVGSSTLPTP 1257
Score = 56.2 bits (134), Expect = 2e-07
Identities = 52/148 (35%), Positives = 61/148 (41%), Gaps = 30/148 (20%)
Query: 974 SGGPGLAPLGAAGHPGMMPHQQ---PPPYPLMHHQMPPPHP------PQPGQIPGPGSMM 1024
+G P PL AG P P + PPP PL +PPP P P P +PG G +
Sbjct: 1127 AGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG-IP 1185
Query: 1025 PGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNIL--GPRVPLTAPNGMYPPP---PQ 1079
P +PG IP G+G PP PP+PG + P PL P PPP P
Sbjct: 1186 PPPPLPGVGIPPPPPL---PGAGIPPP--PPLPGMGIPPAPAPPLPPPGTGIPPPPLLPV 1240
Query: 1080 QQPP----------PPPPADGVPPPPAP 1097
PP P P G PPP P
Sbjct: 1241 SGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
Score = 39.3 bits (90), Expect = 0.021
Identities = 55/223 (24%), Positives = 77/223 (34%), Gaps = 51/223 (22%)
Query: 916 ELETIMDREKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQHGQNPQQAHQH-S 974
E E ++ ++A+ Q+QQ +Q +L+ +QQ +Q Q + P S
Sbjct: 191 EQEDLLSDIQQAIRLQQQQ----------QQQLQLQLQQQQQQQQLQGAEEPAAPPTAVS 240
Query: 975 GGPG---------LAPLGAAGH-PGMMPHQQPP------PYPLMHHQMPPPHPPQPGQIP 1018
PG L P G AG PG +Q P L P PP PG +P
Sbjct: 241 PQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLP 300
Query: 1019 -GPGSMMPGQHMPGRMIPTVAANIHP-SGSGPTPPGMP---------------------P 1055
+P + P+ A P +G G G P
Sbjct: 301 VSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRG 360
Query: 1056 MPGNILGPRVPLTAPNGMYPPPPQQ-QPPPPPPADGVPPPPAP 1097
PG P V AP + P ++ Q P P A +P PAP
Sbjct: 361 SPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAP 403
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 72.0 bits (175), Expect = 3e-12
Identities = 56/163 (34%), Positives = 68/163 (41%), Gaps = 29/163 (17%)
Query: 969 QAHQHSGGPGLAPLGAAGHPGMMPHQQP-----PPYPLMHHQMPPPHP------------ 1011
Q H P P AG PG+ P PP P + +PPP P
Sbjct: 209 QFHFKMEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTG 268
Query: 1012 PQPGQIPGPGSM---MPGQHMPGRMIPTVAANIHPSGSGPTPPGM---PPMPGNILGPRV 1065
P P PGP + PG H P ++ A+ +HP G PP PP PG + P
Sbjct: 269 PAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPG-VHPPTS 327
Query: 1066 PLTAPN-GMYPPPPQQQPPPP---PPADGV-PPPPAPGPPASA 1103
+ P G++PP P PP P PPA GV PP P PP SA
Sbjct: 328 GVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSA 370
Score = 69.7 bits (169), Expect = 1e-11
Identities = 48/149 (32%), Positives = 60/149 (40%), Gaps = 14/149 (9%)
Query: 964 GQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQP-----PPYPLMHHQMPPPHPPQPGQIP 1018
G +P H PG+ P + HP P PP P +H P HPP PG P
Sbjct: 307 GVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHP 366
Query: 1019 GPGS----MMPGQHMPGRMIPTVAANIHPSGSG--PTPPGMPPMPGNILGPRVPLTAPN- 1071
P + PG H + A +HP G P PG+ P P + P P P
Sbjct: 367 PPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGV-HPSAPGVHPQP 425
Query: 1072 -GMYPPPPQQQPPPPPPADGVPPPPAPGP 1099
G++P P PP P P PP P+ GP
Sbjct: 426 PGVHPSNPGVHPPTPMPPMLRPPLPSEGP 454
Score = 65.1 bits (157), Expect = 4e-10
Identities = 43/119 (36%), Positives = 51/119 (42%), Gaps = 9/119 (7%)
Query: 964 GQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPG---QIPGP 1020
G +P H PG+ P +AG P P P +H Q P HPP PG Q PG
Sbjct: 349 GVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAA-PAVHPQAPGVHPPAPGMHPQAPGV 407
Query: 1021 GSMMPGQHMPGRMIPTVAANIHPSGSGPTPP-GMPPMPGNILGPRVPLTAPNGMYPPPP 1078
PG H + +HPS G PP MPPM L P +P P + PPPP
Sbjct: 408 HPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPM----LRPPLPSEGPGNIPPPPP 462
Score = 63.5 bits (153), Expect = 1e-09
Identities = 50/144 (34%), Positives = 58/144 (40%), Gaps = 16/144 (11%)
Query: 975 GGPGLAPLGAAGHPGMMPHQQP-----PPYPLMHHQMPPPHPPQPGQIP---GPGSMMPG 1026
G P L P HP P PP P +H P HPP PG P G PG
Sbjct: 276 GPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPG 335
Query: 1027 QHMPGRMIPTVAANIHPSGSG--PTPPGMPPMPGNILGPRVPLTAP--NGMYPPPPQQQP 1082
H P + A +HP G P PG+ P P + P+ P P ++P P P
Sbjct: 336 VHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHP 395
Query: 1083 PPP---PPADGVPPPPAPGPPASA 1103
P P P A GV P P PG SA
Sbjct: 396 PAPGMHPQAPGVHPQP-PGVHPSA 418
Score = 48.5 bits (114), Expect = 3e-05
Identities = 23/58 (39%), Positives = 27/58 (46%)
Query: 1048 PTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPPPPAPGPPASAAP 1105
P PP +P P + P PL PP P+ PPPPP +PP P GP S P
Sbjct: 218 PAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPP 275
Score = 46.6 bits (109), Expect = 1e-04
Identities = 27/59 (45%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
Query: 1050 PPGM---PPMPGNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPPPPAPGPPASAAP 1105
PPG+ PP N L PR PL P + PPPP P PP P G P PGPP P
Sbjct: 227 PPGVKRPPPPLMNGLPPRPPL--PESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPP 283
Score = 36.6 bits (83), Expect = 0.13
Identities = 23/64 (35%), Positives = 27/64 (42%), Gaps = 4/64 (6%)
Query: 958 MEQQQHGQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQ-PGQ 1016
M Q G +PQ H PG+ P HP P P P M + PP P + PG
Sbjct: 400 MHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPM---LRPPLPSEGPGN 456
Query: 1017 IPGP 1020
IP P
Sbjct: 457 IPPP 460
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 71.6 bits (174), Expect = 4e-12
Identities = 67/236 (28%), Positives = 100/236 (42%), Gaps = 43/236 (18%)
Query: 900 VETQMKKLEIKLRHFEELETIMDREKEALEQQRQQLLTERQNFHMEQLKYAE-------- 951
V+ Q++ E++ + F+ L +RE + E+Q H +QL+ E
Sbjct: 434 VDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYP------HKDQLQEYEKQWKTWQG 487
Query: 952 -LRARQQMEQQQHGQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPH 1010
++A Q Q++ +Q+ G + P P + Q PPP P M + PP
Sbjct: 488 HMKATQSYLQEKVNSFQNMKNQYMGNMSMPP------PFVPYSQMPPPLPTMPPPVLPPS 541
Query: 1011 PPQPGQIPG-PGSMMPGQHMPGRMIPTVAANIHPSGSGPT------PPGMPPMPGNILGP 1063
P P P P ++ P P M P++ ++ P G P+ PP +PP + GP
Sbjct: 542 LPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGP 601
Query: 1064 RVPL-------TAPNGMYPPPPQQQPPPPP--PADGVP---PP---PAPGPPASAA 1104
L TAP + P PP PPP P GVP PP AP PPAS++
Sbjct: 602 PPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSS 657
Score = 52.8 bits (125), Expect = 2e-06
Identities = 56/169 (33%), Positives = 66/169 (39%), Gaps = 44/169 (26%)
Query: 950 AELRARQQMEQQQHGQNPQQAHQHSGGPGLAPLGAAGHPGMMP-----HQQPPPYPLMHH 1004
A+L+ QQM Q+Q Q Q H H P L P P +MP QPPP P
Sbjct: 59 AQLQQLQQMHQKQM-QCVLQPH-HLPPPPLPP------PPVMPGGGYGDWQPPPPP---- 106
Query: 1005 QMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPR 1064
MPPP PGP Q + +H GP PG+ PM + P
Sbjct: 107 -MPPP--------PGPALSYQKQQQYKHQM------LHHQRDGP--PGLVPM--ELESPP 147
Query: 1065 VPLTAPNGMYPPPPQQ-QPPPPPPADGVPP-------PPAPGPPASAAP 1105
P G Y PP Q PPP PP PP PPA P+ + P
Sbjct: 148 ESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPP 196
Score = 50.8 bits (120), Expect = 7e-06
Identities = 36/99 (36%), Positives = 41/99 (41%), Gaps = 14/99 (14%)
Query: 1005 QMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPR 1064
QM PPQ ++ S PG M P P GS PP M PG+I+ P
Sbjct: 1484 QMADHLPPQESRLQNTSSR------PG-MYP-------PPGSYRPPPPMGKPPGSIVRPS 1529
Query: 1065 VPLTAPNGMYPPPPQQQPPPPPPADGVPPPPAPGPPASA 1103
P + PP PPPPPP PPPP P SA
Sbjct: 1530 APPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSA 1568
Score = 47.0 bits (110), Expect = 1e-04
Identities = 41/150 (27%), Positives = 55/150 (36%), Gaps = 17/150 (11%)
Query: 959 EQQQHGQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIP 1018
++QQ ++ HQ G PGL P+ P P P MPPP PP P P
Sbjct: 118 QKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPP-PSYYP 176
Query: 1019 GPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPP 1078
P S P ++P A PS S P+ + P P + + P
Sbjct: 177 -PTSSQP--YLP-------PAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLP 226
Query: 1079 QQQPPPPPPADG------VPPPPAPGPPAS 1102
Q P P+ G + PPP PP +
Sbjct: 227 SSQASPSRPSQGHSKSQLLAPPPPSAPPGN 256
Score = 43.1 bits (100), Expect = 0.001
Identities = 47/185 (25%), Positives = 57/185 (30%), Gaps = 73/185 (39%)
Query: 986 GHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPG------------------------ 1021
G G H PPP P PPP P PGPG
Sbjct: 6 GRYGGSSHYPPPPVP------PPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLA 59
Query: 1022 --------------SMMPGQHMPGRMIPTVAANIHPSGS----GPTPPGMPPMPGNILGP 1063
++ H+P +P + P G P PP MPP PG L
Sbjct: 60 QLQQLQQMHQKQMQCVLQPHHLPPPPLP--PPPVMPGGGYGDWQPPPPPMPPPPGPALSY 117
Query: 1064 RV-----------PLTAPNGMYP----PPPQQQPPPP----PPADGVPPPPAPG----PP 1100
+ P G+ P PP+ P PP PP+ PPP P PP
Sbjct: 118 QKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPP 177
Query: 1101 ASAAP 1105
S+ P
Sbjct: 178 TSSQP 182
Score = 37.7 bits (86), Expect = 0.061
Identities = 42/179 (23%), Positives = 59/179 (32%), Gaps = 39/179 (21%)
Query: 945 EQLKYAELRARQQMEQQQHGQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPLMHH 1004
++LK + Q + + G PQ A H + PGM P P +
Sbjct: 1461 QELKMLREQKEQLQKMKDFGSEPQMA-DHLPPQESRLQNTSSRPGMYP-------PPGSY 1512
Query: 1005 QMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPR 1064
+ PPP PG I P + +P P P P PP +PP P ++ P+
Sbjct: 1513 RPPPPMGKPPGSIVRPSAPPARSSVPVTRPPV------PIPPPPPPPPLPPPPP-VIKPQ 1565
Query: 1065 VPLTAPN--------GMYPPPPQQ--------------QPP--PPPPADGVPPPPAPGP 1099
G++ +Q P PPPP PPP P P
Sbjct: 1566 TSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVP 1624
Score = 37.0 bits (84), Expect = 0.10
Identities = 42/155 (27%), Positives = 54/155 (34%), Gaps = 19/155 (12%)
Query: 961 QQHGQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGP 1020
Q P Q H S LAP + PG Q P + Q P P
Sbjct: 229 QASPSRPSQGHSKS--QLLAPPPPSAPPGNKTTVQQEPLE-SGAKNKSTEQQQAAPEPDP 285
Query: 1021 GSMMPG--------QHMPGRMIPTVAANIHPSG--SGPTPPGMPPMPGNILGPRVPLTAP 1070
+M P QH+ T +H G GP P P + V + A
Sbjct: 286 STMTPQEQQQYWYRQHLLSLQQRT---KVHLPGHKKGPVVAKDTPEP---VKEEVTVPAT 339
Query: 1071 NGMYPPPPQQQPPPPPPADGVPPPPAPGPPASAAP 1105
+ + P ++PP PPP + VPPP P P S P
Sbjct: 340 SQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDP 374
Score = 35.4 bits (80), Expect = 0.30
Identities = 39/122 (31%), Positives = 50/122 (40%), Gaps = 18/122 (14%)
Query: 977 PGLAP-LGAAGHPGMMPHQQ-----PPPY---PLMHHQMPPP-H--PPQPGQIPGPGSMM 1024
PG+ P L +AG P ++P PPP P + PPP PP P PG
Sbjct: 576 PGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
Query: 1025 PGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPL---TAPNGMYPPPPQQQ 1081
PG +P + P + A P S +P P L P P+ +AP Y PP Q
Sbjct: 636 PG--VPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLP-TPVSFGSAPPTTYHPPLQSA 692
Query: 1082 PP 1083
P
Sbjct: 693 GP 694
Score = 32.0 bits (71), Expect = 3.3
Identities = 18/48 (37%), Positives = 20/48 (41%), Gaps = 2/48 (4%)
Query: 1058 GNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPPPPAPGPPASAAP 1105
GN+ P P P PPP PPP P PP P PA+ P
Sbjct: 512 GNMSMP--PPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPP 557
>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
Length = 548
Score = 70.5 bits (171), Expect = 8e-12
Identities = 49/134 (36%), Positives = 53/134 (39%), Gaps = 27/134 (20%)
Query: 973 HSGGPGLAPLGAAGHPGMMPHQQPP------PYPLMHHQMPPPHPPQPGQIPGPGSMMPG 1026
H GGPG G G P PH P +P+ H+ P PP P P P M G
Sbjct: 383 HGGGPG----GPGGGPHSFPHPLPSLTGGHGGHPMQHN---PNGPPPPWMQPPPPPMNQG 435
Query: 1027 QHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQ-QQPPPP 1085
H PG P GS P G+ L GM PPPP PPPP
Sbjct: 436 PHPPGHHGPPPMDQY--LGSTPVGSGV-----------YRLHQGKGMMPPPPMGMMPPPP 482
Query: 1086 PPADGVPPPPAPGP 1099
PP G PPPP GP
Sbjct: 483 PPPSGQPPPPPSGP 496
Score = 35.0 bits (79), Expect = 0.39
Identities = 24/81 (29%), Positives = 29/81 (35%), Gaps = 9/81 (11%)
Query: 964 GQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPP------YPLMHHQMPPPHPPQPGQI 1017
G + HQ G P+G P P QPPP P Q PP PP P
Sbjct: 457 GSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSS 516
Query: 1018 PGPGSMMPGQHMPGRMIPTVA 1038
+ +P Q R +P A
Sbjct: 517 MASSTPLPWQQ---RSLPAAA 534
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 70.5 bits (171), Expect = 8e-12
Identities = 49/134 (36%), Positives = 53/134 (39%), Gaps = 27/134 (20%)
Query: 973 HSGGPGLAPLGAAGHPGMMPHQQPP------PYPLMHHQMPPPHPPQPGQIPGPGSMMPG 1026
H GGPG G G P PH P +P+ H+ P PP P P P M G
Sbjct: 383 HGGGPG----GPGGGPHSFPHPLPSLTGGHGGHPMQHN---PNGPPPPWMQPPPPPMNQG 435
Query: 1027 QHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQ-QQPPPP 1085
H PG P GS P G+ L GM PPPP PPPP
Sbjct: 436 PHPPGHHGPPPMDQY--LGSTPVGSGV-----------YRLHQGKGMMPPPPMGMMPPPP 482
Query: 1086 PPADGVPPPPAPGP 1099
PP G PPPP GP
Sbjct: 483 PPPSGQPPPPPSGP 496
Score = 64.7 bits (156), Expect = 5e-10
Identities = 45/149 (30%), Positives = 51/149 (34%), Gaps = 14/149 (9%)
Query: 964 GQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPL------MHHQMPPPHPPQPGQI 1017
G + HQ G P+G P P QPPP P Q PP PP P
Sbjct: 457 GSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSS 516
Query: 1018 PGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNG-MYPP 1076
+ +P Q +G+G PP P P N M P
Sbjct: 517 MASSTPLPWQQ-------NTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPL 569
Query: 1077 PPQQQPPPPPPADGVPPPPAPGPPASAAP 1105
PP QPP PP A PPPP PG P
Sbjct: 570 PPGVQPPLPPGAPPPPPPPPPGSAGMMIP 598
Score = 30.4 bits (67), Expect = 9.7
Identities = 19/62 (30%), Positives = 23/62 (37%), Gaps = 8/62 (12%)
Query: 959 EQQQHGQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIP 1018
+QQ A Q G P + PL P + P PPP PPP P G +
Sbjct: 546 QQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPP--------PPPPPGSAGMMI 597
Query: 1019 GP 1020
P
Sbjct: 598 PP 599
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 70.5 bits (171), Expect = 8e-12
Identities = 49/134 (36%), Positives = 53/134 (39%), Gaps = 27/134 (20%)
Query: 973 HSGGPGLAPLGAAGHPGMMPHQQPP------PYPLMHHQMPPPHPPQPGQIPGPGSMMPG 1026
H GGPG G G P PH P +P+ H+ P PP P P P M G
Sbjct: 383 HGGGPG----GPGGGPHSFPHPLPSLTGGHGGHPMQHN---PNGPPPPWMQPPPPPMNQG 435
Query: 1027 QHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQ-QQPPPP 1085
H PG P GS P G+ L GM PPPP PPPP
Sbjct: 436 PHPPGHHGPPPMDQY--LGSTPVGSGV-----------YRLHQGKGMMPPPPMGMMPPPP 482
Query: 1086 PPADGVPPPPAPGP 1099
PP G PPPP GP
Sbjct: 483 PPPSGQPPPPPSGP 496
Score = 67.4 bits (163), Expect = 7e-11
Identities = 50/154 (32%), Positives = 57/154 (37%), Gaps = 22/154 (14%)
Query: 964 GQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPL------MHHQMPPPHPPQPGQI 1017
G + HQ G P+G P P QPPP P Q PP PP P
Sbjct: 457 GSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSS 516
Query: 1018 PGPGSMMPGQHMPGRMIPTVAANIHP-----SGSGPTPPGMPPMPGNILGPRVPLTAPNG 1072
+ +P Q + P + PG P M GN VPL P G
Sbjct: 517 MASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGN--PTMVPL--PPG 572
Query: 1073 MYPP-PPQQQPPPPPPADG------VPPPPAPGP 1099
+ PP PP PPPPPP G PPPP P P
Sbjct: 573 VQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPP 606
Score = 42.7 bits (99), Expect = 0.002
Identities = 33/121 (27%), Positives = 41/121 (33%), Gaps = 28/121 (23%)
Query: 959 EQQQHGQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIP 1018
+QQ A Q G P + PL P + P PPP PPP P G +
Sbjct: 546 QQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPP--------PPPPPGSAGMMY 597
Query: 1019 GPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPP 1078
P P P + + + +G P GMPP P PPPP
Sbjct: 598 APPPPPPPPMDPSNFVTMMGMGV----AGMPPFGMPPAPP----------------PPPP 637
Query: 1079 Q 1079
Q
Sbjct: 638 Q 638
>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform A [Homo sapiens]
Length = 1679
Score = 68.9 bits (167), Expect = 2e-11
Identities = 63/198 (31%), Positives = 82/198 (41%), Gaps = 30/198 (15%)
Query: 924 EKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQHGQNPQQAHQHSGGPGLAPLG 983
+ +AL QQ + QN + QL+ A++ A + + + Q P H G P+
Sbjct: 158 DPQALGQQNRGPTPFNQN-QLHQLR-AQIMAYKMLARGQ----PLPDHLQMAVQGKRPM- 210
Query: 984 AAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMP----GRMIPTVAA 1039
PGM P P + P P P PG PGPG P P G +P
Sbjct: 211 ----PGMQQQMPTLPPPSVSATGPGPGPG-PGPGPGPGPAPPNYSRPHGMGGPNMPPPGP 265
Query: 1040 NIHPSGSGPTPPGMPPMP---GNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPP--- 1093
+ P G PPG PP P G + P + P + PP P +P P PPA VPP
Sbjct: 266 SGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPA--VPPAAS 323
Query: 1094 ---PP---APGPPASAAP 1105
PP +PG PA AP
Sbjct: 324 PVMPPQTQSPGQPAQPAP 341
Score = 35.4 bits (80), Expect = 0.30
Identities = 41/155 (26%), Positives = 50/155 (32%), Gaps = 42/155 (27%)
Query: 981 PLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMM----PGQHMPGRMIPT 1036
PLG PG P P P ++ P PG PG M PG G IPT
Sbjct: 7 PLGGTPRPGPSPGPGPSPGAMLG--------PSPGPSPGSAHSMMGPSPGPPSAGHPIPT 58
Query: 1037 VA----------------ANIHPSGSGPTP-----PGMPPMPGNILG---PRVPLTAPNG 1072
++H G P GM G G P P+ +
Sbjct: 59 QGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQ 118
Query: 1073 MYPPP--PQQQPPPPPPADGVPPPPAPGPPASAAP 1105
YP P + P PA G P+ GP S+ P
Sbjct: 119 GYPSPLGGSEHASSPVPASG----PSSGPQMSSGP 149
Score = 33.1 bits (74), Expect = 1.5
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 5/73 (6%)
Query: 768 DEPEKLEGAEEEKMEADPDGQQPEKAENKVENETDEGDKAQD---GENEKNSEKEQDSEV 824
D+ E E EEE E + +G + E KV+ + +KAQD G + S + V
Sbjct: 1600 DDSEGEESEEEE--EGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPV 1657
Query: 825 SEDTKSEEKETEE 837
D SEE++ E+
Sbjct: 1658 VSDDDSEEEQEED 1670
Score = 30.4 bits (67), Expect = 9.7
Identities = 17/61 (27%), Positives = 29/61 (47%)
Query: 312 ERRDRKASANARKRKHSPSPPPPTPTESRKKSGKKGQASLYGKRRSQKEEDEQEDLTKDM 371
E R +K+S ++ + S P T T SR K + + G+ ++K +LTK M
Sbjct: 1435 EVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKM 1494
Query: 372 E 372
+
Sbjct: 1495 K 1495
>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform F [Homo sapiens]
Length = 1613
Score = 68.9 bits (167), Expect = 2e-11
Identities = 63/198 (31%), Positives = 82/198 (41%), Gaps = 30/198 (15%)
Query: 924 EKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQHGQNPQQAHQHSGGPGLAPLG 983
+ +AL QQ + QN + QL+ A++ A + + + Q P H G P+
Sbjct: 158 DPQALGQQNRGPTPFNQN-QLHQLR-AQIMAYKMLARGQ----PLPDHLQMAVQGKRPM- 210
Query: 984 AAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMP----GRMIPTVAA 1039
PGM P P + P P P PG PGPG P P G +P
Sbjct: 211 ----PGMQQQMPTLPPPSVSATGPGPGPG-PGPGPGPGPAPPNYSRPHGMGGPNMPPPGP 265
Query: 1040 NIHPSGSGPTPPGMPPMP---GNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPP--- 1093
+ P G PPG PP P G + P + P + PP P +P P PPA VPP
Sbjct: 266 SGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPA--VPPAAS 323
Query: 1094 ---PP---APGPPASAAP 1105
PP +PG PA AP
Sbjct: 324 PVMPPQTQSPGQPAQPAP 341
Score = 35.4 bits (80), Expect = 0.30
Identities = 41/155 (26%), Positives = 50/155 (32%), Gaps = 42/155 (27%)
Query: 981 PLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMM----PGQHMPGRMIPT 1036
PLG PG P P P ++ P PG PG M PG G IPT
Sbjct: 7 PLGGTPRPGPSPGPGPSPGAMLG--------PSPGPSPGSAHSMMGPSPGPPSAGHPIPT 58
Query: 1037 VA----------------ANIHPSGSGPTP-----PGMPPMPGNILG---PRVPLTAPNG 1072
++H G P GM G G P P+ +
Sbjct: 59 QGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQ 118
Query: 1073 MYPPP--PQQQPPPPPPADGVPPPPAPGPPASAAP 1105
YP P + P PA G P+ GP S+ P
Sbjct: 119 GYPSPLGGSEHASSPVPASG----PSSGPQMSSGP 149
Score = 33.9 bits (76), Expect = 0.87
Identities = 39/184 (21%), Positives = 74/184 (40%), Gaps = 33/184 (17%)
Query: 213 QDDEEWLRPVMRKEKQVLVHWGFYPDSYDTWVHSNDVDAEIEDPPIPEKPWKVHVKWILD 272
QD+EE P Q++ + + +D ++ D+D E+ P++ + +++
Sbjct: 1256 QDEEEDEVPDDETVNQMIAR---HEEEFDLFMRM-DLDRRREEARNPKRKPR-----LME 1306
Query: 273 TDIFNEWMNEEDYEVDE----------------NRKPVSFRQRISTKN-----EEPVRSP 311
D W+ ++D EV+ +RK V + ++ K EE
Sbjct: 1307 EDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEE 1366
Query: 312 ERRDRKASANARKRKHSP---SPPPPTPTESRKKSGKKGQASLYGKRRSQKEEDEQEDLT 368
+ + ++RKRK S P T T SR K + + G+ ++K +LT
Sbjct: 1367 IEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLT 1426
Query: 369 KDME 372
K M+
Sbjct: 1427 KKMK 1430
Score = 33.1 bits (74), Expect = 1.5
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 5/73 (6%)
Query: 768 DEPEKLEGAEEEKMEADPDGQQPEKAENKVENETDEGDKAQD---GENEKNSEKEQDSEV 824
D+ E E EEE E + +G + E KV+ + +KAQD G + S + V
Sbjct: 1534 DDSEGEESEEEE--EGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPV 1591
Query: 825 SEDTKSEEKETEE 837
D SEE++ E+
Sbjct: 1592 VSDDDSEEEQEED 1604
>gi|192807318 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform E [Homo sapiens]
Length = 1614
Score = 68.9 bits (167), Expect = 2e-11
Identities = 63/198 (31%), Positives = 82/198 (41%), Gaps = 30/198 (15%)
Query: 924 EKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQHGQNPQQAHQHSGGPGLAPLG 983
+ +AL QQ + QN + QL+ A++ A + + + Q P H G P+
Sbjct: 158 DPQALGQQNRGPTPFNQN-QLHQLR-AQIMAYKMLARGQ----PLPDHLQMAVQGKRPM- 210
Query: 984 AAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMP----GRMIPTVAA 1039
PGM P P + P P P PG PGPG P P G +P
Sbjct: 211 ----PGMQQQMPTLPPPSVSATGPGPGPG-PGPGPGPGPAPPNYSRPHGMGGPNMPPPGP 265
Query: 1040 NIHPSGSGPTPPGMPPMP---GNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPP--- 1093
+ P G PPG PP P G + P + P + PP P +P P PPA VPP
Sbjct: 266 SGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPA--VPPAAS 323
Query: 1094 ---PP---APGPPASAAP 1105
PP +PG PA AP
Sbjct: 324 PVMPPQTQSPGQPAQPAP 341
Score = 35.4 bits (80), Expect = 0.30
Identities = 41/155 (26%), Positives = 50/155 (32%), Gaps = 42/155 (27%)
Query: 981 PLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMM----PGQHMPGRMIPT 1036
PLG PG P P P ++ P PG PG M PG G IPT
Sbjct: 7 PLGGTPRPGPSPGPGPSPGAMLG--------PSPGPSPGSAHSMMGPSPGPPSAGHPIPT 58
Query: 1037 VA----------------ANIHPSGSGPTP-----PGMPPMPGNILG---PRVPLTAPNG 1072
++H G P GM G G P P+ +
Sbjct: 59 QGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQ 118
Query: 1073 MYPPP--PQQQPPPPPPADGVPPPPAPGPPASAAP 1105
YP P + P PA G P+ GP S+ P
Sbjct: 119 GYPSPLGGSEHASSPVPASG----PSSGPQMSSGP 149
Score = 33.9 bits (76), Expect = 0.87
Identities = 39/184 (21%), Positives = 74/184 (40%), Gaps = 33/184 (17%)
Query: 213 QDDEEWLRPVMRKEKQVLVHWGFYPDSYDTWVHSNDVDAEIEDPPIPEKPWKVHVKWILD 272
QD+EE P Q++ + + +D ++ D+D E+ P++ + +++
Sbjct: 1256 QDEEEDEVPDDETVNQMIAR---HEEEFDLFMRM-DLDRRREEARNPKRKPR-----LME 1306
Query: 273 TDIFNEWMNEEDYEVDE----------------NRKPVSFRQRISTKN-----EEPVRSP 311
D W+ ++D EV+ +RK V + ++ K EE
Sbjct: 1307 EDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEE 1366
Query: 312 ERRDRKASANARKRKHSP---SPPPPTPTESRKKSGKKGQASLYGKRRSQKEEDEQEDLT 368
+ + ++RKRK S P T T SR K + + G+ ++K +LT
Sbjct: 1367 IEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLT 1426
Query: 369 KDME 372
K M+
Sbjct: 1427 KKMK 1430
Score = 33.1 bits (74), Expect = 1.5
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 5/73 (6%)
Query: 768 DEPEKLEGAEEEKMEADPDGQQPEKAENKVENETDEGDKAQD---GENEKNSEKEQDSEV 824
D+ E E EEE E + +G + E KV+ + +KAQD G + S + V
Sbjct: 1535 DDSEGEESEEEE--EGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPV 1592
Query: 825 SEDTKSEEKETEE 837
D SEE++ E+
Sbjct: 1593 VSDDDSEEEQEED 1605
>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform D [Homo sapiens]
Length = 1616
Score = 68.9 bits (167), Expect = 2e-11
Identities = 63/198 (31%), Positives = 82/198 (41%), Gaps = 30/198 (15%)
Query: 924 EKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQHGQNPQQAHQHSGGPGLAPLG 983
+ +AL QQ + QN + QL+ A++ A + + + Q P H G P+
Sbjct: 158 DPQALGQQNRGPTPFNQN-QLHQLR-AQIMAYKMLARGQ----PLPDHLQMAVQGKRPM- 210
Query: 984 AAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMP----GRMIPTVAA 1039
PGM P P + P P P PG PGPG P P G +P
Sbjct: 211 ----PGMQQQMPTLPPPSVSATGPGPGPG-PGPGPGPGPAPPNYSRPHGMGGPNMPPPGP 265
Query: 1040 NIHPSGSGPTPPGMPPMP---GNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPP--- 1093
+ P G PPG PP P G + P + P + PP P +P P PPA VPP
Sbjct: 266 SGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPA--VPPAAS 323
Query: 1094 ---PP---APGPPASAAP 1105
PP +PG PA AP
Sbjct: 324 PVMPPQTQSPGQPAQPAP 341
Score = 35.4 bits (80), Expect = 0.30
Identities = 41/155 (26%), Positives = 50/155 (32%), Gaps = 42/155 (27%)
Query: 981 PLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMM----PGQHMPGRMIPT 1036
PLG PG P P P ++ P PG PG M PG G IPT
Sbjct: 7 PLGGTPRPGPSPGPGPSPGAMLG--------PSPGPSPGSAHSMMGPSPGPPSAGHPIPT 58
Query: 1037 VA----------------ANIHPSGSGPTP-----PGMPPMPGNILG---PRVPLTAPNG 1072
++H G P GM G G P P+ +
Sbjct: 59 QGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQ 118
Query: 1073 MYPPP--PQQQPPPPPPADGVPPPPAPGPPASAAP 1105
YP P + P PA G P+ GP S+ P
Sbjct: 119 GYPSPLGGSEHASSPVPASG----PSSGPQMSSGP 149
Score = 33.1 bits (74), Expect = 1.5
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 5/73 (6%)
Query: 768 DEPEKLEGAEEEKMEADPDGQQPEKAENKVENETDEGDKAQD---GENEKNSEKEQDSEV 824
D+ E E EEE E + +G + E KV+ + +KAQD G + S + V
Sbjct: 1537 DDSEGEESEEEE--EGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPV 1594
Query: 825 SEDTKSEEKETEE 837
D SEE++ E+
Sbjct: 1595 VSDDDSEEEQEED 1607
Score = 32.7 bits (73), Expect = 1.9
Identities = 39/187 (20%), Positives = 74/187 (39%), Gaps = 36/187 (19%)
Query: 213 QDDEEWLRPVMRKEKQVLVHWGFYPDSYDTWVHSNDVDAEIEDPPIPEKPWKVHVKWILD 272
QD+EE P Q++ + + +D ++ D+D E+ P++ + +++
Sbjct: 1256 QDEEEDEVPDDETVNQMIAR---HEEEFDLFMRM-DLDRRREEARNPKRKPR-----LME 1306
Query: 273 TDIFNEWMNEEDYEVDE----------------NRKPVSFRQRISTKN--------EEPV 308
D W+ ++D EV+ +RK V + ++ K EE
Sbjct: 1307 EDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKTLKAIEEGT 1366
Query: 309 RSPERRDRKASANARKRKHSP---SPPPPTPTESRKKSGKKGQASLYGKRRSQKEEDEQE 365
+ + ++RKRK S P T T SR K + + G+ ++K
Sbjct: 1367 LEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPP 1426
Query: 366 DLTKDME 372
+LTK M+
Sbjct: 1427 NLTKKMK 1433
>gi|192807314 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform C [Homo sapiens]
Length = 1617
Score = 68.9 bits (167), Expect = 2e-11
Identities = 63/198 (31%), Positives = 82/198 (41%), Gaps = 30/198 (15%)
Query: 924 EKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQHGQNPQQAHQHSGGPGLAPLG 983
+ +AL QQ + QN + QL+ A++ A + + + Q P H G P+
Sbjct: 158 DPQALGQQNRGPTPFNQN-QLHQLR-AQIMAYKMLARGQ----PLPDHLQMAVQGKRPM- 210
Query: 984 AAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMP----GRMIPTVAA 1039
PGM P P + P P P PG PGPG P P G +P
Sbjct: 211 ----PGMQQQMPTLPPPSVSATGPGPGPG-PGPGPGPGPAPPNYSRPHGMGGPNMPPPGP 265
Query: 1040 NIHPSGSGPTPPGMPPMP---GNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPP--- 1093
+ P G PPG PP P G + P + P + PP P +P P PPA VPP
Sbjct: 266 SGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPA--VPPAAS 323
Query: 1094 ---PP---APGPPASAAP 1105
PP +PG PA AP
Sbjct: 324 PVMPPQTQSPGQPAQPAP 341
Score = 35.4 bits (80), Expect = 0.30
Identities = 41/155 (26%), Positives = 50/155 (32%), Gaps = 42/155 (27%)
Query: 981 PLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMM----PGQHMPGRMIPT 1036
PLG PG P P P ++ P PG PG M PG G IPT
Sbjct: 7 PLGGTPRPGPSPGPGPSPGAMLG--------PSPGPSPGSAHSMMGPSPGPPSAGHPIPT 58
Query: 1037 VA----------------ANIHPSGSGPTP-----PGMPPMPGNILG---PRVPLTAPNG 1072
++H G P GM G G P P+ +
Sbjct: 59 QGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQ 118
Query: 1073 MYPPP--PQQQPPPPPPADGVPPPPAPGPPASAAP 1105
YP P + P PA G P+ GP S+ P
Sbjct: 119 GYPSPLGGSEHASSPVPASG----PSSGPQMSSGP 149
Score = 33.1 bits (74), Expect = 1.5
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 5/73 (6%)
Query: 768 DEPEKLEGAEEEKMEADPDGQQPEKAENKVENETDEGDKAQD---GENEKNSEKEQDSEV 824
D+ E E EEE E + +G + E KV+ + +KAQD G + S + V
Sbjct: 1538 DDSEGEESEEEE--EGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPV 1595
Query: 825 SEDTKSEEKETEE 837
D SEE++ E+
Sbjct: 1596 VSDDDSEEEQEED 1608
Score = 32.7 bits (73), Expect = 1.9
Identities = 39/187 (20%), Positives = 74/187 (39%), Gaps = 36/187 (19%)
Query: 213 QDDEEWLRPVMRKEKQVLVHWGFYPDSYDTWVHSNDVDAEIEDPPIPEKPWKVHVKWILD 272
QD+EE P Q++ + + +D ++ D+D E+ P++ + +++
Sbjct: 1256 QDEEEDEVPDDETVNQMIAR---HEEEFDLFMRM-DLDRRREEARNPKRKPR-----LME 1306
Query: 273 TDIFNEWMNEEDYEVDE----------------NRKPVSFRQRISTKN--------EEPV 308
D W+ ++D EV+ +RK V + ++ K EE
Sbjct: 1307 EDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKTLKAIEEGT 1366
Query: 309 RSPERRDRKASANARKRKHSP---SPPPPTPTESRKKSGKKGQASLYGKRRSQKEEDEQE 365
+ + ++RKRK S P T T SR K + + G+ ++K
Sbjct: 1367 LEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPP 1426
Query: 366 DLTKDME 372
+LTK M+
Sbjct: 1427 NLTKKMK 1433
>gi|192807312 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform B [Homo sapiens]
Length = 1647
Score = 68.9 bits (167), Expect = 2e-11
Identities = 63/198 (31%), Positives = 82/198 (41%), Gaps = 30/198 (15%)
Query: 924 EKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQHGQNPQQAHQHSGGPGLAPLG 983
+ +AL QQ + QN + QL+ A++ A + + + Q P H G P+
Sbjct: 158 DPQALGQQNRGPTPFNQN-QLHQLR-AQIMAYKMLARGQ----PLPDHLQMAVQGKRPM- 210
Query: 984 AAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMP----GRMIPTVAA 1039
PGM P P + P P P PG PGPG P P G +P
Sbjct: 211 ----PGMQQQMPTLPPPSVSATGPGPGPG-PGPGPGPGPAPPNYSRPHGMGGPNMPPPGP 265
Query: 1040 NIHPSGSGPTPPGMPPMP---GNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPP--- 1093
+ P G PPG PP P G + P + P + PP P +P P PPA VPP
Sbjct: 266 SGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPA--VPPAAS 323
Query: 1094 ---PP---APGPPASAAP 1105
PP +PG PA AP
Sbjct: 324 PVMPPQTQSPGQPAQPAP 341
Score = 35.4 bits (80), Expect = 0.30
Identities = 41/155 (26%), Positives = 50/155 (32%), Gaps = 42/155 (27%)
Query: 981 PLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMM----PGQHMPGRMIPT 1036
PLG PG P P P ++ P PG PG M PG G IPT
Sbjct: 7 PLGGTPRPGPSPGPGPSPGAMLG--------PSPGPSPGSAHSMMGPSPGPPSAGHPIPT 58
Query: 1037 VA----------------ANIHPSGSGPTP-----PGMPPMPGNILG---PRVPLTAPNG 1072
++H G P GM G G P P+ +
Sbjct: 59 QGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQ 118
Query: 1073 MYPPP--PQQQPPPPPPADGVPPPPAPGPPASAAP 1105
YP P + P PA G P+ GP S+ P
Sbjct: 119 GYPSPLGGSEHASSPVPASG----PSSGPQMSSGP 149
Score = 33.1 bits (74), Expect = 1.5
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 5/73 (6%)
Query: 768 DEPEKLEGAEEEKMEADPDGQQPEKAENKVENETDEGDKAQD---GENEKNSEKEQDSEV 824
D+ E E EEE E + +G + E KV+ + +KAQD G + S + V
Sbjct: 1568 DDSEGEESEEEE--EGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPV 1625
Query: 825 SEDTKSEEKETEE 837
D SEE++ E+
Sbjct: 1626 VSDDDSEEEQEED 1638
Score = 32.0 bits (71), Expect = 3.3
Identities = 32/149 (21%), Positives = 59/149 (39%), Gaps = 29/149 (19%)
Query: 248 DVDAEIEDPPIPEKPWKVHVKWILDTDIFNEWMNEEDYEVDE----------------NR 291
D+D E+ P++ + +++ D W+ ++D EV+ +R
Sbjct: 1320 DLDRRREEARNPKRKPR-----LMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHR 1374
Query: 292 KPVSFRQRISTKN-----EEPVRSPERRDRKASANARKRKHSP---SPPPPTPTESRKKS 343
K V + ++ K EE + + ++RKRK S P T T SR K
Sbjct: 1375 KEVDYSDSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKD 1434
Query: 344 GKKGQASLYGKRRSQKEEDEQEDLTKDME 372
+ + G+ ++K +LTK M+
Sbjct: 1435 DESKKQKKRGRPPAEKLSPNPPNLTKKMK 1463
>gi|21071056 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform B [Homo sapiens]
Length = 1647
Score = 68.9 bits (167), Expect = 2e-11
Identities = 63/198 (31%), Positives = 82/198 (41%), Gaps = 30/198 (15%)
Query: 924 EKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQHGQNPQQAHQHSGGPGLAPLG 983
+ +AL QQ + QN + QL+ A++ A + + + Q P H G P+
Sbjct: 158 DPQALGQQNRGPTPFNQN-QLHQLR-AQIMAYKMLARGQ----PLPDHLQMAVQGKRPM- 210
Query: 984 AAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMP----GRMIPTVAA 1039
PGM P P + P P P PG PGPG P P G +P
Sbjct: 211 ----PGMQQQMPTLPPPSVSATGPGPGPG-PGPGPGPGPAPPNYSRPHGMGGPNMPPPGP 265
Query: 1040 NIHPSGSGPTPPGMPPMP---GNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPP--- 1093
+ P G PPG PP P G + P + P + PP P +P P PPA VPP
Sbjct: 266 SGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPA--VPPAAS 323
Query: 1094 ---PP---APGPPASAAP 1105
PP +PG PA AP
Sbjct: 324 PVMPPQTQSPGQPAQPAP 341
Score = 35.4 bits (80), Expect = 0.30
Identities = 41/155 (26%), Positives = 50/155 (32%), Gaps = 42/155 (27%)
Query: 981 PLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMM----PGQHMPGRMIPT 1036
PLG PG P P P ++ P PG PG M PG G IPT
Sbjct: 7 PLGGTPRPGPSPGPGPSPGAMLG--------PSPGPSPGSAHSMMGPSPGPPSAGHPIPT 58
Query: 1037 VA----------------ANIHPSGSGPTP-----PGMPPMPGNILG---PRVPLTAPNG 1072
++H G P GM G G P P+ +
Sbjct: 59 QGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQ 118
Query: 1073 MYPPP--PQQQPPPPPPADGVPPPPAPGPPASAAP 1105
YP P + P PA G P+ GP S+ P
Sbjct: 119 GYPSPLGGSEHASSPVPASG----PSSGPQMSSGP 149
Score = 33.1 bits (74), Expect = 1.5
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 5/73 (6%)
Query: 768 DEPEKLEGAEEEKMEADPDGQQPEKAENKVENETDEGDKAQD---GENEKNSEKEQDSEV 824
D+ E E EEE E + +G + E KV+ + +KAQD G + S + V
Sbjct: 1568 DDSEGEESEEEE--EGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPV 1625
Query: 825 SEDTKSEEKETEE 837
D SEE++ E+
Sbjct: 1626 VSDDDSEEEQEED 1638
Score = 32.0 bits (71), Expect = 3.3
Identities = 32/149 (21%), Positives = 59/149 (39%), Gaps = 29/149 (19%)
Query: 248 DVDAEIEDPPIPEKPWKVHVKWILDTDIFNEWMNEEDYEVDE----------------NR 291
D+D E+ P++ + +++ D W+ ++D EV+ +R
Sbjct: 1320 DLDRRREEARNPKRKPR-----LMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHR 1374
Query: 292 KPVSFRQRISTKN-----EEPVRSPERRDRKASANARKRKHSP---SPPPPTPTESRKKS 343
K V + ++ K EE + + ++RKRK S P T T SR K
Sbjct: 1375 KEVDYSDSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKD 1434
Query: 344 GKKGQASLYGKRRSQKEEDEQEDLTKDME 372
+ + G+ ++K +LTK M+
Sbjct: 1435 DESKKQKKRGRPPAEKLSPNPPNLTKKMK 1463
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 68.6 bits (166), Expect = 3e-11
Identities = 67/238 (28%), Positives = 89/238 (37%), Gaps = 20/238 (8%)
Query: 868 TAAAAALASAATKAKHLAAVEERKIKSLVALLVETQMKKLE-----IKLRHFEELETIMD 922
TAAAA A+AA+ + +E + ++ +L LE ++ RH E E
Sbjct: 12 TAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHGPEPERTR- 70
Query: 923 REKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQHGQNPQQAHQHSGGPGLAPL 982
E E L QQR L + + Y R +++ + G P + G A
Sbjct: 71 AELEKLIQQRAVLRVSYKG----SISY---RNAARVQPPRRGATPPAPPRAPRGAPAAAA 123
Query: 983 GAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIH 1042
AA P P PPP P+ P P+ PG PG A
Sbjct: 124 AAAPPP--TPAPPPPPAPVA--AAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAA 179
Query: 1043 PSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPPPPAPGPP 1100
P + PP + P G P + A PPPPQ PP PP PPPP P PP
Sbjct: 180 PPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQ---PPAPPQQQQPPPPQPQPP 234
Score = 42.7 bits (99), Expect = 0.002
Identities = 25/67 (37%), Positives = 27/67 (40%), Gaps = 6/67 (8%)
Query: 1038 AANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPPPPAP 1097
AA + P G TPP P PR A PPP PPPP P P AP
Sbjct: 96 AARVQPPRRGATPPAPPR------APRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAP 149
Query: 1098 GPPASAA 1104
A+AA
Sbjct: 150 RAAAAAA 156
Score = 32.0 bits (71), Expect = 3.3
Identities = 33/144 (22%), Positives = 58/144 (40%), Gaps = 14/144 (9%)
Query: 297 RQRISTKNEEPVRSPERRDR-KASANARKRKHSPSPPPPTPTESRKKSGKKGQASLYGKR 355
R R+ EE + R +R + A A R P PP + +R K+G ++
Sbjct: 270 RGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAAS-ARPSRSKRGGEERVLEK 328
Query: 356 RSQKEEDEQEDLTKDMEDPTPVPNIEEVVLPKNVNLKKDSENTPVKGGTVADLDEQDEET 415
++++DE ED D+ + + VP + ++ L + K E+ +E
Sbjct: 329 EEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAK--------ERVKEW 380
Query: 416 VTAGGKEDED----PAKGDQSRSV 435
G + +D PA G +R V
Sbjct: 381 TPCGPHQGQDEGRGPAPGSGTRQV 404
Score = 30.8 bits (68), Expect = 7.4
Identities = 18/46 (39%), Positives = 21/46 (45%), Gaps = 4/46 (8%)
Query: 981 PLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPG 1026
P AA P + P QPP P Q P PPQP P G++ G
Sbjct: 202 PAVAAREPPLPPPPQPPAPP----QQQQPPPPQPQPPPEGGAVRAG 243
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 67.8 bits (164), Expect = 5e-11
Identities = 60/176 (34%), Positives = 66/176 (37%), Gaps = 52/176 (29%)
Query: 977 PGLAPLGAAGHPGM-----MPHQQ--PPPYPLMHHQMPP-PHPPQPGQIPGPGSMMPGQH 1028
P A LG A PG +P Q PP +P HQ PP PH P P P P S M G
Sbjct: 377 PLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPP---PPPSSYMTGMS 433
Query: 1029 ---------------------------MPGRMIPTVAANIHPS--GSGPTPPGMPPMPGN 1059
+P P HP P PP +PP P +
Sbjct: 434 TTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPAS 493
Query: 1060 ILGPRVPLTAPNGMYPPPPQQQ----PPPP---PPADGVPPPPAPG---PPASAAP 1105
P +P P YPPPP PPPP PP VPP P PG PPAS P
Sbjct: 494 FPPPAIPPPTPG--YPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPP 547
Score = 61.6 bits (148), Expect = 4e-09
Identities = 49/151 (32%), Positives = 53/151 (35%), Gaps = 33/151 (21%)
Query: 964 GQNPQQAHQHSGGPGLAPL----GAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPG 1019
G Q+ + GP L G H PH PP P PPP PP P P
Sbjct: 443 GYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPP------PPPVPPPPASFPP 496
Query: 1020 PGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPP-- 1077
P P PG P N P PP P PR+P T +PPP
Sbjct: 497 PAIPPP---TPGYPPPPPTYN----------PNFPPPP-----PRLPPTHAVPPHPPPGL 538
Query: 1078 ---PQQQPPPPPPADGVPPPPAPGPPASAAP 1105
P PPP P G PP P P PP P
Sbjct: 539 GLPPASYPPPAVPPGGQPPVPPPIPPPGMPP 569
Score = 55.5 bits (132), Expect = 3e-07
Identities = 49/147 (33%), Positives = 60/147 (40%), Gaps = 21/147 (14%)
Query: 949 YAELRARQQMEQQQHGQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPP 1008
Y L++ + E +G P G P P +P P+ PPP P PP
Sbjct: 444 YQSLQSMMKTEGPSYGALPPAY----GPPAHLPYHPHVYP---PNPPPPPVPPPPASFPP 496
Query: 1009 PH--PPQPGQIPGPGSMMPG-QHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRV 1065
P PP PG P P + P P R+ PT A HP PPG+ P + P V
Sbjct: 497 PAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHP------PPGLGLPPASYPPPAV 550
Query: 1066 PLTAPNGMYPPPPQQQPPP-PPPADGV 1091
P P G PP P PPP PP G+
Sbjct: 551 P---PGGQ-PPVPPPIPPPGMPPVGGL 573
Score = 39.3 bits (90), Expect = 0.021
Identities = 46/185 (24%), Positives = 58/185 (31%), Gaps = 30/185 (16%)
Query: 944 MEQLKYAELRARQQMEQQQHGQNPQQAHQHSGGPGLAPL-----------GAAGHPGMMP 992
+E + + L Q +QQ P Q Q P L P + P P
Sbjct: 247 LEDICHQILDLYSQGKQQMPHHTPHQLQQP---PSLQPTPQVPQVQQSQPSQSSEPSQ-P 302
Query: 993 HQQPPPYPLMHHQ------MPPPHPPQPGQIPGPGSMMPGQHM-----PGRMIPTVAANI 1041
Q+ P P Q P P P P Q+ + P + P IP +
Sbjct: 303 QQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTH 362
Query: 1042 HPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPPP----PAP 1097
P PP P LG P + P Q PP P PPP P P
Sbjct: 363 PPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPP 422
Query: 1098 GPPAS 1102
PP+S
Sbjct: 423 PPPSS 427
Score = 37.7 bits (86), Expect = 0.061
Identities = 38/124 (30%), Positives = 44/124 (35%), Gaps = 17/124 (13%)
Query: 991 MPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTP 1050
MPH P P P PQ Q S P Q P + P A P
Sbjct: 265 MPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQ--PQQKDPQQPAQQQQPAQQPKK 322
Query: 1051 PG-MPPMPGNILGPRVPLTAP---NGMYPPPPQQQP------PPPPPADGVPPPPAPGPP 1100
P P P + R + +P N PPP + P PP PPA PPP PP
Sbjct: 323 PSPQPSSPRQV--KRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAH---PPPDRKPP 377
Query: 1101 ASAA 1104
+AA
Sbjct: 378 LAAA 381
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 67.4 bits (163), Expect = 7e-11
Identities = 45/135 (33%), Positives = 49/135 (36%), Gaps = 34/135 (25%)
Query: 976 GPGLAPLGAAGHPGMMP-----HQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMP 1030
GP LAP A P +P + P P + + PPP PP P P
Sbjct: 1421 GPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPP-----PAPTPQ------- 1468
Query: 1031 GRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQPPPPPPADG 1090
P PP PP P L PL AP PPPP PPPPP
Sbjct: 1469 -----------------PQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPS 1511
Query: 1091 VPPPPAPGPPASAAP 1105
PPPP P AAP
Sbjct: 1512 PPPPPPPAAAPLAAP 1526
Score = 54.3 bits (129), Expect = 6e-07
Identities = 38/132 (28%), Positives = 49/132 (37%), Gaps = 36/132 (27%)
Query: 977 PGLAPLGAAG--HPGMMPHQQPP-PYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMPGRM 1033
PGL + G P ++ + PP P P Q PP PP P P
Sbjct: 1437 PGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPP---------------PQPA 1481
Query: 1034 IPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPP 1093
+P+ + P+ S P PP +PP PPP PPPPPP P
Sbjct: 1482 LPSPPPLVAPTPSSPPPPPLPPP------------------PPPAMPSPPPPPPPAAAPL 1523
Query: 1094 PPAPGPPASAAP 1105
P PA+ +P
Sbjct: 1524 AAPPEEPAAPSP 1535
Score = 50.1 bits (118), Expect = 1e-05
Identities = 37/101 (36%), Positives = 43/101 (42%), Gaps = 24/101 (23%)
Query: 1007 PPPHPPQP----GQIPGPGSMMP-GQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNIL 1061
PP P G PGP + P G + PGR SG+GP PG+ P
Sbjct: 967 PPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRA----------SGAGPETPGLGLDPNK-- 1014
Query: 1062 GPRVPLTA---PNGMYPPPPQQQPPPPPPADGVPPPPAPGP 1099
P +P T P G+ P Q PPPPP PPPP P P
Sbjct: 1015 PPELPSTVNAEPLGLIQSGPHQAAPPPPP----PPPPPPAP 1051
Score = 43.1 bits (100), Expect = 0.001
Identities = 48/172 (27%), Positives = 58/172 (33%), Gaps = 53/172 (30%)
Query: 976 GPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPH---------------PPQPGQI--- 1017
G G LGA + PPP P P PH PP P Q+
Sbjct: 750 GAGAKELGA-----FLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPS 804
Query: 1018 -------PGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNI--------LG 1062
P P + G H+ + + P P PP PPMP + L
Sbjct: 805 VLSHAPSPSPSASKVGVHL----LEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLE 860
Query: 1063 PRVP---LTAPNGMYPPPPQQQ------PPPPPPAD-GVPPPPAPG-PPASA 1103
P P L + PP Q+ P PP P D GV PP + G PA A
Sbjct: 861 PAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGA 912
Score = 42.4 bits (98), Expect = 0.002
Identities = 39/154 (25%), Positives = 50/154 (32%), Gaps = 37/154 (24%)
Query: 979 LAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVA 1038
LA G G G+ P Q PP P PP PP P +P +++ +
Sbjct: 208 LAGGGVLGPAGLGPAQTPPYRP-----GPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSS 262
Query: 1039 ANIHP-SGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQPPPPP----------- 1086
++ SG+ P PP P PR + P Q PPPPP
Sbjct: 263 PQLYNFSGAAPGPP-----PPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCG 317
Query: 1087 ---------------PADGVPPPPAPGPPASAAP 1105
P G P P G P+ A P
Sbjct: 318 GSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGP 351
Score = 35.0 bits (79), Expect = 0.39
Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 24/76 (31%)
Query: 1054 PPMPG--NILGPRVPLTAPNGMYPPPP-------------------QQQPPPPPPADGVP 1092
PP+ G + P P AP P PP +++PPP PP P
Sbjct: 1408 PPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTP 1467
Query: 1093 ---PPPAPGPPASAAP 1105
PPP P PP A P
Sbjct: 1468 QPQPPPPPPPPQPALP 1483
Score = 33.9 bits (76), Expect = 0.87
Identities = 30/110 (27%), Positives = 39/110 (35%), Gaps = 15/110 (13%)
Query: 977 PGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPT 1036
P + L A HP +P P P PP P + P ++ H+ PT
Sbjct: 143 PSSSALSAYQHPASFG-SRPFPVPSSLSLQDPPFSPPANGLLSPHDVL---HLKPSQAPT 198
Query: 1037 VAANIHPSGSGPTPPGMPPMPGN-ILGPRVPLTAPNGMYPPPPQQQPPPP 1085
V P+ G + G +LGP A Y P P PPPP
Sbjct: 199 V----------PSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPP 238
Score = 33.9 bits (76), Expect = 0.87
Identities = 31/115 (26%), Positives = 39/115 (33%), Gaps = 26/115 (22%)
Query: 975 GGPGLAPLGAAGHP--------GMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPG 1026
GG G AG P G P PP Y P P PG+ G G PG
Sbjct: 955 GGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYD-------PYGPYCPGRASGAGPETPG 1007
Query: 1027 QHMPGRMIPTVAANIHPSGSG-----------PTPPGMPPMPGNILGPRVPLTAP 1070
+ P + + ++ G P PP PP P P+ LT+P
Sbjct: 1008 LGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSP 1062
Score = 33.5 bits (75), Expect = 1.1
Identities = 42/140 (30%), Positives = 54/140 (38%), Gaps = 25/140 (17%)
Query: 965 QNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPG-PGSM 1023
Q+ +A +SGGP P G PPP L Q P Q GQ+ G G
Sbjct: 467 QDLSKAPSYSGGPPQPPSG------------PPPPGLATCQSYSPDQLQ-GQLYGVQGEP 513
Query: 1024 MPGQHMPGRMIPTVAANI-HPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQP 1082
PG + +PT + ++ + +G P G G GP G P +P
Sbjct: 514 YPGPAAHSQGLPTASPSLSYSTGHSPALSGH----GGGWGPSS--LGGGGEASPSHIIRP 567
Query: 1083 PPPPPADGVPP----PPAPG 1098
PPA G PP P APG
Sbjct: 568 LQSPPATGRPPGVGSPGAPG 587
Score = 32.0 bits (71), Expect = 3.3
Identities = 51/203 (25%), Positives = 64/203 (31%), Gaps = 67/203 (33%)
Query: 963 HGQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYP--------LMHHQMPPPHP--- 1011
H +P + G L P G P P PPP P L H + P P
Sbjct: 808 HAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPR 867
Query: 1012 --PQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPG----------MPPMPGN 1059
P+ P PG+M Q + G + P A P +G PP P P
Sbjct: 868 LRPEESLDP-PGAM---QELLGALEPLPPA---PGDTGVGPPNSEGKDPAGAYRSPSPQG 920
Query: 1060 ILGPR-VPLTA-----------PNGMYPP-----------------PPQQQ--------P 1082
PR VPLT+ +P PP+ + P
Sbjct: 921 TKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGP 980
Query: 1083 PPPPPADGVPPPPAPGPPASAAP 1105
PP PPA P PG + A P
Sbjct: 981 PPGPPAYDPYGPYCPGRASGAGP 1003
Score = 31.6 bits (70), Expect = 4.3
Identities = 19/68 (27%), Positives = 24/68 (35%), Gaps = 16/68 (23%)
Query: 1054 PPMPGNILGPRVPLTAPNGMYPPPPQQQPPPP----------------PPADGVPPPPAP 1097
PP+P G + G PPP+ PPP P +P PPAP
Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAP 1729
Query: 1098 GPPASAAP 1105
P+ P
Sbjct: 1730 EKPSLLRP 1737
Score = 30.4 bits (67), Expect = 9.7
Identities = 21/49 (42%), Positives = 24/49 (48%), Gaps = 6/49 (12%)
Query: 1062 GPRVPLTAPNGMYPP-PPQQQPPPPPPADGV-PPPPA----PGPPASAA 1104
G R P G+ PP P + PP PA G+ P PPA P PP S A
Sbjct: 1292 GKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGA 1340
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 67.0 bits (162), Expect = 9e-11
Identities = 79/338 (23%), Positives = 129/338 (38%), Gaps = 85/338 (25%)
Query: 779 EKMEADPDGQQPEKAENKVENETDEGDKAQDGENEKNSEKEQDSEVSEDTKSEEKETEEN 838
E + + G + +++ + G ++ E ++ +EQ + + + E+E E
Sbjct: 109 EVLNSQETGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMER 168
Query: 839 KELTDTCKERESDTGKKKVEHEISEGNVATAAAAALASAATKAKHLAAVEERKIKSLVAL 898
+ L ERE ++E E +E+ +++
Sbjct: 169 ERLERERLERE------RLERE-------------------------RLEQEQLER---- 193
Query: 899 LVETQMKKLEIKLRHFEELETIMDREK-EALEQQRQQLLTERQNFHMEQLKYAELRARQQ 957
E Q ++ + +L E LE E+ E L+++RQ+ ER+ + + E ++Q
Sbjct: 194 --ERQERERQERLERQERLERQERLERQERLDRERQE-RQERERLERLERERQERERQEQ 250
Query: 958 MEQQQHGQNPQQAHQHSGGPGL--APL------GAAGHPGMMPHQQPPPYP-----LMHH 1004
+E++Q ++ + P PL +A PG+ QP P ++
Sbjct: 251 LEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGP 310
Query: 1005 QMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPR 1064
PPP PP P PGP S + P PPG PP P
Sbjct: 311 LAPPPPPPLP---PGPA--------------------QASVALPPPPGPPP------PPP 341
Query: 1065 VPLTAPNGMYPPPPQQQPPPPPPADGVPPPPAPGPPAS 1102
+P T P PPPP PPPP PPPPAP PAS
Sbjct: 342 LPSTGPPPPPPPPPLPNQVPPPP----PPPPAPPLPAS 375
Score = 65.1 bits (157), Expect = 4e-10
Identities = 61/213 (28%), Positives = 87/213 (40%), Gaps = 45/213 (21%)
Query: 901 ETQMKKLEIKLRHFEELETIMDREK-EALEQQRQQLLTERQNFHMEQLKYAELRARQQME 959
E Q ++ + +L E LE E+ E L+++RQ+ ER+ + + E ++Q+E
Sbjct: 194 ERQERERQERLERQERLERQERLERQERLDRERQER-QERERLERLERERQERERQEQLE 252
Query: 960 QQQHGQNPQQAHQHSGGPGLA--PLGA------AGHPGMMPHQQPPPYP-----LMHHQM 1006
++Q ++ + P PL + A PG+ QP P ++
Sbjct: 253 REQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLA 312
Query: 1007 PPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVP 1066
PPP PP P PGP S + P PPG PP P +P
Sbjct: 313 PPPPPPLP---PGPAQA--------------------SVALPPPPGPPPPPP------LP 343
Query: 1067 LTAPNGMYPPPP-QQQPPPPPPADGVPPPPAPG 1098
T P PPPP Q PPPPP PP PA G
Sbjct: 344 STGPPPPPPPPPLPNQVPPPPPPPPAPPLPASG 376
Score = 41.2 bits (95), Expect = 0.005
Identities = 61/279 (21%), Positives = 99/279 (35%), Gaps = 50/279 (17%)
Query: 769 EPEKLEGAEEEKMEADPDGQQPEKAENK-VENETDEGDKAQDGENEKNSEKEQDSEVSED 827
E E++E E+ + + + E+ E + +E E E ++ + E ++ E+++ E E
Sbjct: 162 ERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQER 221
Query: 828 TKSEEKETEENKELTDTCKERESDTGKKKVEHEISEGNVATAAAAALASAATKAKHLAAV 887
E +E +E + L +ER+ ++++E E E
Sbjct: 222 LDRERQERQERERLERLERERQERERQEQLEREQLEWE---------------------- 259
Query: 888 EERKIKSLVA-LLVETQMKKLEIKLRHFEELETIMDREKEALEQQRQQLLTERQNFHMEQ 946
ER+I S A VET + + L E + + E QQ +
Sbjct: 260 RERRISSAAAPASVETPLNSV---LGDSSASEPGLQAASQPAETPSQQGIV--------- 307
Query: 947 LKYAELRARQQMEQQQHGQNPQQAH----QHSGGPGLAPLGAAGHPGMMPHQQPPPYPLM 1002
L P QA G P PL + G P PPP PL
Sbjct: 308 -----LGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPP-----PPPPPPPLP 357
Query: 1003 HHQMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANI 1041
+ PPP PP +P G + R + +AA I
Sbjct: 358 NQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAAAI 396
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 67.0 bits (162), Expect = 9e-11
Identities = 79/338 (23%), Positives = 129/338 (38%), Gaps = 85/338 (25%)
Query: 779 EKMEADPDGQQPEKAENKVENETDEGDKAQDGENEKNSEKEQDSEVSEDTKSEEKETEEN 838
E + + G + +++ + G ++ E ++ +EQ + + + E+E E
Sbjct: 109 EVLNSQETGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMER 168
Query: 839 KELTDTCKERESDTGKKKVEHEISEGNVATAAAAALASAATKAKHLAAVEERKIKSLVAL 898
+ L ERE ++E E +E+ +++
Sbjct: 169 ERLERERLERE------RLERE-------------------------RLEQEQLER---- 193
Query: 899 LVETQMKKLEIKLRHFEELETIMDREK-EALEQQRQQLLTERQNFHMEQLKYAELRARQQ 957
E Q ++ + +L E LE E+ E L+++RQ+ ER+ + + E ++Q
Sbjct: 194 --ERQERERQERLERQERLERQERLERQERLDRERQE-RQERERLERLERERQERERQEQ 250
Query: 958 MEQQQHGQNPQQAHQHSGGPGL--APL------GAAGHPGMMPHQQPPPYP-----LMHH 1004
+E++Q ++ + P PL +A PG+ QP P ++
Sbjct: 251 LEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGP 310
Query: 1005 QMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPR 1064
PPP PP P PGP S + P PPG PP P
Sbjct: 311 LAPPPPPPLP---PGPA--------------------QASVALPPPPGPPP------PPP 341
Query: 1065 VPLTAPNGMYPPPPQQQPPPPPPADGVPPPPAPGPPAS 1102
+P T P PPPP PPPP PPPPAP PAS
Sbjct: 342 LPSTGPPPPPPPPPLPNQVPPPP----PPPPAPPLPAS 375
Score = 65.1 bits (157), Expect = 4e-10
Identities = 61/213 (28%), Positives = 87/213 (40%), Gaps = 45/213 (21%)
Query: 901 ETQMKKLEIKLRHFEELETIMDREK-EALEQQRQQLLTERQNFHMEQLKYAELRARQQME 959
E Q ++ + +L E LE E+ E L+++RQ+ ER+ + + E ++Q+E
Sbjct: 194 ERQERERQERLERQERLERQERLERQERLDRERQER-QERERLERLERERQERERQEQLE 252
Query: 960 QQQHGQNPQQAHQHSGGPGLA--PLGA------AGHPGMMPHQQPPPYP-----LMHHQM 1006
++Q ++ + P PL + A PG+ QP P ++
Sbjct: 253 REQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLA 312
Query: 1007 PPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVP 1066
PPP PP P PGP S + P PPG PP P +P
Sbjct: 313 PPPPPPLP---PGPAQA--------------------SVALPPPPGPPPPPP------LP 343
Query: 1067 LTAPNGMYPPPP-QQQPPPPPPADGVPPPPAPG 1098
T P PPPP Q PPPPP PP PA G
Sbjct: 344 STGPPPPPPPPPLPNQVPPPPPPPPAPPLPASG 376
Score = 41.2 bits (95), Expect = 0.005
Identities = 61/279 (21%), Positives = 99/279 (35%), Gaps = 50/279 (17%)
Query: 769 EPEKLEGAEEEKMEADPDGQQPEKAENK-VENETDEGDKAQDGENEKNSEKEQDSEVSED 827
E E++E E+ + + + E+ E + +E E E ++ + E ++ E+++ E E
Sbjct: 162 ERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQER 221
Query: 828 TKSEEKETEENKELTDTCKERESDTGKKKVEHEISEGNVATAAAAALASAATKAKHLAAV 887
E +E +E + L +ER+ ++++E E E
Sbjct: 222 LDRERQERQERERLERLERERQERERQEQLEREQLEWE---------------------- 259
Query: 888 EERKIKSLVA-LLVETQMKKLEIKLRHFEELETIMDREKEALEQQRQQLLTERQNFHMEQ 946
ER+I S A VET + + L E + + E QQ +
Sbjct: 260 RERRISSAAAPASVETPLNSV---LGDSSASEPGLQAASQPAETPSQQGIV--------- 307
Query: 947 LKYAELRARQQMEQQQHGQNPQQAH----QHSGGPGLAPLGAAGHPGMMPHQQPPPYPLM 1002
L P QA G P PL + G P PPP PL
Sbjct: 308 -----LGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPP-----PPPPPPPLP 357
Query: 1003 HHQMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANI 1041
+ PPP PP +P G + R + +AA I
Sbjct: 358 NQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAAAI 396
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sapiens]
Length = 505
Score = 67.0 bits (162), Expect = 9e-11
Identities = 46/122 (37%), Positives = 55/122 (45%), Gaps = 24/122 (19%)
Query: 994 QQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPP-- 1051
+Q PP P PPP PP P GP P GR P + P+ + P PP
Sbjct: 274 RQAPPPPPPSRGGPPPPPPPPHN-SGP----PPPPARGRGAPPPPPSRAPTAAPPPPPPS 328
Query: 1052 ----GMPPMPGNIL----GPRVPLTAPNGMYPPPPQ-----QQPPPPPPADGVPPPPAPG 1098
+PP P N + P +P +AP+G PPPP PPPPP PPPP PG
Sbjct: 329 RPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPP----PPPPPPG 384
Query: 1099 PP 1100
PP
Sbjct: 385 PP 386
Score = 65.9 bits (159), Expect = 2e-10
Identities = 45/122 (36%), Positives = 48/122 (39%), Gaps = 25/122 (20%)
Query: 1002 MHHQMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGM------PP 1055
+ Q PPP PP G GP P H G P G+ P PP PP
Sbjct: 272 LRRQAPPPPPPSRG---GPPPPPPPPHNSGPPPPPARGR----GAPPPPPSRAPTAAPPP 324
Query: 1056 MPGNILGPRVPLTAPNGMYPPP--------PQQQPPPPPPADGV----PPPPAPGPPASA 1103
P + VP PN MYPPP P PPPPP GV PPPP P PP
Sbjct: 325 PPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPG 384
Query: 1104 AP 1105
P
Sbjct: 385 PP 386
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/139 (36%), Positives = 60/139 (43%), Gaps = 32/139 (23%)
Query: 964 GQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPG-QIPGPGS 1022
G P H+ GP P G P P + P P PPP P +P +P P
Sbjct: 286 GPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAP------PPPPPSRPSVAVPPPP- 338
Query: 1023 MMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQP 1082
P RM P + PS S P+ P PP P ++LG V AP PPPP P
Sbjct: 339 -------PNRMYPPPPPAL-PS-SAPSGP--PPPPPSVLG--VGPVAP----PPPP---P 378
Query: 1083 PPPPPADGVPPPPAPGPPA 1101
PPPPP PPP PG P+
Sbjct: 379 PPPPPG----PPPPPGLPS 393
Score = 37.4 bits (85), Expect = 0.079
Identities = 22/59 (37%), Positives = 24/59 (40%), Gaps = 10/59 (16%)
Query: 988 PGMMPHQQPPPYPLM------HHQMPPPHPPQPGQIPGPGSMMPGQHMPGRMIPTVAAN 1040
P P PPP P + PPP PP PG P PG G H +PT A N
Sbjct: 351 PSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDH----QVPTTAGN 405
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,618,216
Number of Sequences: 37866
Number of extensions: 3654765
Number of successful extensions: 74173
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1001
Number of HSP's successfully gapped in prelim test: 2177
Number of HSP's that attempted gapping in prelim test: 24717
Number of HSP's gapped (non-prelim): 25867
length of query: 1105
length of database: 18,247,518
effective HSP length: 113
effective length of query: 992
effective length of database: 13,968,660
effective search space: 13856910720
effective search space used: 13856910720
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.