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Search of human proteins with 188528658
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188528658 transmembrane protein 182 [Homo sapiens]
(229 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188528658 transmembrane protein 182 [Homo sapiens] 482 e-136
gi|42542386 solute carrier family 22 (organic anion/cation trans... 40 0.001
gi|21361975 voltage-dependent calcium channel gamma-7 subunit [H... 36 0.024
gi|239754660 PREDICTED: hypothetical protein [Homo sapiens] 33 0.26
gi|239749194 PREDICTED: hypothetical protein XP_002346946 [Homo ... 33 0.26
gi|239743274 PREDICTED: hypothetical protein XP_002342783 [Homo ... 33 0.26
gi|239508955 PREDICTED: hypothetical protein [Homo sapiens] 33 0.26
gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Ho... 33 0.26
gi|4503893 beta-1,4-N-acetyl-galactosaminyl transferase 1 [Homo ... 29 2.9
gi|17318565 cyclin E2 [Homo sapiens] 29 3.8
gi|4505907 peripheral myelin protein 22 [Homo sapiens] 29 3.8
gi|24430165 peripheral myelin protein 22 [Homo sapiens] 29 3.8
gi|24430163 peripheral myelin protein 22 [Homo sapiens] 29 3.8
gi|239753906 PREDICTED: hypothetical protein [Homo sapiens] 28 6.5
gi|239748450 PREDICTED: hypothetical protein [Homo sapiens] 28 6.5
gi|239742411 PREDICTED: hypothetical protein XP_002342509 [Homo ... 28 6.5
gi|116812584 SID1 transmembrane family, member 1 [Homo sapiens] 28 6.5
gi|197276661 paired box 1 [Homo sapiens] 28 8.5
gi|22748765 claudin domain containing 2 [Homo sapiens] 28 8.5
>gi|188528658 transmembrane protein 182 [Homo sapiens]
Length = 229
Score = 482 bits (1240), Expect = e-136
Identities = 229/229 (100%), Positives = 229/229 (100%)
Query: 1 MRLNIAIFFGALFGALGVLLFLVAFGSDYWLLATEVGRCSGEKNIENVTFHHEGFFWRCW 60
MRLNIAIFFGALFGALGVLLFLVAFGSDYWLLATEVGRCSGEKNIENVTFHHEGFFWRCW
Sbjct: 1 MRLNIAIFFGALFGALGVLLFLVAFGSDYWLLATEVGRCSGEKNIENVTFHHEGFFWRCW 60
Query: 61 FNGIVEENDSNIWKFWYTNQPPSKNCTHAYLSPYPFMRGEHNSTSYDSAVIYRGFWAVLM 120
FNGIVEENDSNIWKFWYTNQPPSKNCTHAYLSPYPFMRGEHNSTSYDSAVIYRGFWAVLM
Sbjct: 61 FNGIVEENDSNIWKFWYTNQPPSKNCTHAYLSPYPFMRGEHNSTSYDSAVIYRGFWAVLM 120
Query: 121 LLGVVAVVIASFLIICAAPFASHFLYKAGGGSYIAAGILFSLVVMLYVIWVQAVADMESY 180
LLGVVAVVIASFLIICAAPFASHFLYKAGGGSYIAAGILFSLVVMLYVIWVQAVADMESY
Sbjct: 121 LLGVVAVVIASFLIICAAPFASHFLYKAGGGSYIAAGILFSLVVMLYVIWVQAVADMESY 180
Query: 181 RNMKMKDCLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVVGWHIQIHH 229
RNMKMKDCLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVVGWHIQIHH
Sbjct: 181 RNMKMKDCLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVVGWHIQIHH 229
>gi|42542386 solute carrier family 22 (organic anion/cation
transporter), member 9 [Homo sapiens]
Length = 553
Score = 40.4 bits (93), Expect = 0.001
Identities = 34/127 (26%), Positives = 51/127 (40%), Gaps = 29/127 (22%)
Query: 99 GEHNSTSYDSAVIYRGFWAVLMLLGVVAVVIASFLIICAAPFASHFLYKAGGGSYIAAGI 158
G H S + + R + + ++G A + +FLI C+ F S IAA
Sbjct: 163 GGHLSDRFGRRFVLRWCYLQVAIVGTCAALAPTFLIYCSLRFLSG----------IAAMS 212
Query: 159 LFSLVVMLYVIWVQAVADMESYRNMKMKDCLDFTPSVLYGWSFFLAPAGIFFSLLAGLLF 218
L + +ML W ++R M G + + P+GI F LAGL F
Sbjct: 213 LITNTIMLIAEWA-------THRFQAM------------GITLGMCPSGIAFMTLAGLAF 253
Query: 219 LVVGWHI 225
+ WHI
Sbjct: 254 AIRDWHI 260
>gi|21361975 voltage-dependent calcium channel gamma-7 subunit [Homo
sapiens]
Length = 275
Score = 36.2 bits (82), Expect = 0.024
Identities = 50/220 (22%), Positives = 86/220 (39%), Gaps = 35/220 (15%)
Query: 11 ALFGALGVLLFLVAFGSDYWLLATEVGRCSGEKNIENVTFHHEGFFWRCWFNG------- 63
++FGA G+LL +A +DYWL E + E H G + C+F G
Sbjct: 14 SVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWRVCFFAGREKGRCV 73
Query: 64 -----------IVEENDSNIWKFWYTNQP-PSKNC----THAYLSPYPFMRGEHNSTSYD 107
+V EN NI K T P P + T +S +R + ++
Sbjct: 74 ASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIGHIRPQRTILAFV 133
Query: 108 SAVIYRGFWAVLMLLGVVAVVIASFLIICAAPFAS--HFLYKAGGGSYIAAGILF---SL 162
S + + + +++G+V + + + P +S +F Y+ G AA
Sbjct: 134 SGIFFI-LSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAASSFLLKEGA 192
Query: 163 VVMLYVIWVQAVADMESYR------NMKMKDCLDFTPSVL 196
VM ++ + A+ E YR ++ DC D++ L
Sbjct: 193 GVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFL 232
>gi|239754660 PREDICTED: hypothetical protein [Homo sapiens]
Length = 221
Score = 32.7 bits (73), Expect = 0.26
Identities = 32/118 (27%), Positives = 57/118 (48%), Gaps = 15/118 (12%)
Query: 117 AVLMLLGVVAVVIASFLIICAA----PFASHFLYKAGGGSYIAAGILFSLVVMLYVIWVQ 172
++ ++LG V ++ A FL PFAS F + +++ A I F ++ V
Sbjct: 69 SIYIILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGACAFLALVL 128
Query: 173 AVADMESYRNMKMKDCLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVVG-----WHI 225
++++ R MK+ L F SVL W +++ GIF ++AG + L+ WH+
Sbjct: 129 HALEIKALR-MKLGP-LQF--SVL--WPYYVLGFGIFLFIVAGTICLIQEMVCPCWHL 180
>gi|239749194 PREDICTED: hypothetical protein XP_002346946 [Homo
sapiens]
Length = 221
Score = 32.7 bits (73), Expect = 0.26
Identities = 32/118 (27%), Positives = 57/118 (48%), Gaps = 15/118 (12%)
Query: 117 AVLMLLGVVAVVIASFLIICAA----PFASHFLYKAGGGSYIAAGILFSLVVMLYVIWVQ 172
++ ++LG V ++ A FL PFAS F + +++ A I F ++ V
Sbjct: 69 SIYIILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGACAFLALVL 128
Query: 173 AVADMESYRNMKMKDCLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVVG-----WHI 225
++++ R MK+ L F SVL W +++ GIF ++AG + L+ WH+
Sbjct: 129 HALEIKALR-MKLGP-LQF--SVL--WPYYVLGFGIFLFIVAGTICLIQEMVCPCWHL 180
>gi|239743274 PREDICTED: hypothetical protein XP_002342783 [Homo
sapiens]
Length = 221
Score = 32.7 bits (73), Expect = 0.26
Identities = 32/118 (27%), Positives = 57/118 (48%), Gaps = 15/118 (12%)
Query: 117 AVLMLLGVVAVVIASFLIICAA----PFASHFLYKAGGGSYIAAGILFSLVVMLYVIWVQ 172
++ ++LG V ++ A FL PFAS F + +++ A I F ++ V
Sbjct: 69 SIYIILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGACAFLALVL 128
Query: 173 AVADMESYRNMKMKDCLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVVG-----WHI 225
++++ R MK+ L F SVL W +++ GIF ++AG + L+ WH+
Sbjct: 129 HALEIKALR-MKLGP-LQF--SVL--WPYYVLGFGIFLFIVAGTICLIQEMVCPCWHL 180
>gi|239508955 PREDICTED: hypothetical protein [Homo sapiens]
Length = 221
Score = 32.7 bits (73), Expect = 0.26
Identities = 32/118 (27%), Positives = 57/118 (48%), Gaps = 15/118 (12%)
Query: 117 AVLMLLGVVAVVIASFLIICAA----PFASHFLYKAGGGSYIAAGILFSLVVMLYVIWVQ 172
++ ++LG V ++ A FL PFAS F + +++ A I F ++ V
Sbjct: 69 SIYIILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGACAFLALVL 128
Query: 173 AVADMESYRNMKMKDCLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVVG-----WHI 225
++++ R MK+ L F SVL W +++ GIF ++AG + L+ WH+
Sbjct: 129 HALEIKALR-MKLGP-LQF--SVL--WPYYVLGFGIFLFIVAGTICLIQEMVCPCWHL 180
>gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Homo
sapiens]
Length = 323
Score = 32.7 bits (73), Expect = 0.26
Identities = 44/205 (21%), Positives = 80/205 (39%), Gaps = 38/205 (18%)
Query: 20 LFLVAFGSDYWLLATEVGRC-------SGEKNIENVTFHHEGFFWRCWFNGIVEENDSNI 72
L +A G+DYWL + V + + +KN E +T H G + C G + I
Sbjct: 23 LMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMT--HSGLWRTCCLEGNFKGLCKQI 80
Query: 73 WKFWYTNQPPSKNCTHAYLSPYPFMRGEHNSTSYDSAVIYRGFWAVLMLLGVVAVVIASF 132
F P A + Y F+R S+ + + +L+ +G + + + F
Sbjct: 81 DHF------PEDADYEADTAEY-FLRAVRASSIFPILSV------ILLFMGGLCIAASEF 127
Query: 133 LIICAAPFASHFLYKAGGGSYIAAGILFSLVVMLYVIWVQAVADMESYRNMKMKDCLDFT 192
H + + G +++AG+ + +++Y+ A A S + K
Sbjct: 128 YK------TRHNIILSAGIFFVSAGLSNIIGIIVYI---SANAGDPSKSDSKKN------ 172
Query: 193 PSVLYGWSFFLAPAGIFFSLLAGLL 217
S YGWSF+ + + G+L
Sbjct: 173 -SYSYGWSFYFGALSFIIAEMVGVL 196
>gi|4503893 beta-1,4-N-acetyl-galactosaminyl transferase 1 [Homo
sapiens]
Length = 533
Score = 29.3 bits (64), Expect = 2.9
Identities = 18/63 (28%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 137 AAPFASHFLYKAGGGSYIAAGILFSLVVMLYVIWV-QAVADMESYRNMKMKDCLDFTPSV 195
+ P+ H+L G G + + S V YV+WV R ++ D L+ TP
Sbjct: 321 SGPYVEHYLMPFGKGWFAGRNLAVSQVTTKYVLWVDDDFVFTARTRLERLVDVLERTPLD 380
Query: 196 LYG 198
L G
Sbjct: 381 LVG 383
>gi|17318565 cyclin E2 [Homo sapiens]
Length = 404
Score = 28.9 bits (63), Expect = 3.8
Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 118 VLMLLGVVAVVIASFLIICAAPFASHFLYKAGGGSYIAAGILFSLVVMLYVIWVQAVADM 177
+L L+G+ ++ IAS L AP F Y G + L+++ + W +
Sbjct: 184 MLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTI 243
Query: 178 ESYRNMKMK-DCLDFTPSVL 196
S+ N+ ++ D L P VL
Sbjct: 244 ISWLNLFLQVDALKDAPKVL 263
>gi|4505907 peripheral myelin protein 22 [Homo sapiens]
Length = 160
Score = 28.9 bits (63), Expect = 3.8
Identities = 23/102 (22%), Positives = 51/102 (50%), Gaps = 14/102 (13%)
Query: 120 MLLGVVAVVIASFLIICAAPFASHFLYKAGGGSYIAAGILFSLVVMLYVIWVQAVADMES 179
M+L ++ +++ FL C F GG YI +F ++ L V+ + A + +
Sbjct: 69 MILSIIFSILSLFLFFCQL-----FTLTKGGRFYITG--IFQILAGLCVM---SAAAIYT 118
Query: 180 YRNMKMKDCLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVV 221
R+ + D++ YG+++ LA +LL+G++++++
Sbjct: 119 VRHPEWHLNSDYS----YGFAYILAWVAFPLALLSGVIYVIL 156
>gi|24430165 peripheral myelin protein 22 [Homo sapiens]
Length = 160
Score = 28.9 bits (63), Expect = 3.8
Identities = 23/102 (22%), Positives = 51/102 (50%), Gaps = 14/102 (13%)
Query: 120 MLLGVVAVVIASFLIICAAPFASHFLYKAGGGSYIAAGILFSLVVMLYVIWVQAVADMES 179
M+L ++ +++ FL C F GG YI +F ++ L V+ + A + +
Sbjct: 69 MILSIIFSILSLFLFFCQL-----FTLTKGGRFYITG--IFQILAGLCVM---SAAAIYT 118
Query: 180 YRNMKMKDCLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVV 221
R+ + D++ YG+++ LA +LL+G++++++
Sbjct: 119 VRHPEWHLNSDYS----YGFAYILAWVAFPLALLSGVIYVIL 156
>gi|24430163 peripheral myelin protein 22 [Homo sapiens]
Length = 160
Score = 28.9 bits (63), Expect = 3.8
Identities = 23/102 (22%), Positives = 51/102 (50%), Gaps = 14/102 (13%)
Query: 120 MLLGVVAVVIASFLIICAAPFASHFLYKAGGGSYIAAGILFSLVVMLYVIWVQAVADMES 179
M+L ++ +++ FL C F GG YI +F ++ L V+ + A + +
Sbjct: 69 MILSIIFSILSLFLFFCQL-----FTLTKGGRFYITG--IFQILAGLCVM---SAAAIYT 118
Query: 180 YRNMKMKDCLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVV 221
R+ + D++ YG+++ LA +LL+G++++++
Sbjct: 119 VRHPEWHLNSDYS----YGFAYILAWVAFPLALLSGVIYVIL 156
>gi|239753906 PREDICTED: hypothetical protein [Homo sapiens]
Length = 129
Score = 28.1 bits (61), Expect = 6.5
Identities = 13/41 (31%), Positives = 20/41 (48%)
Query: 188 CLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVVGWHIQIH 228
CL+F PS + FL P+G SL +G+ + +H
Sbjct: 3 CLEFVPSDVRASPEFLPPSGFVVSLTSGVKLQTFAVSVTVH 43
>gi|239748450 PREDICTED: hypothetical protein [Homo sapiens]
Length = 129
Score = 28.1 bits (61), Expect = 6.5
Identities = 13/41 (31%), Positives = 20/41 (48%)
Query: 188 CLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVVGWHIQIH 228
CL+F PS + FL P+G SL +G+ + +H
Sbjct: 3 CLEFVPSDVRASPEFLPPSGFVVSLTSGVKLQTFAVSVTVH 43
>gi|239742411 PREDICTED: hypothetical protein XP_002342509 [Homo
sapiens]
Length = 129
Score = 28.1 bits (61), Expect = 6.5
Identities = 13/41 (31%), Positives = 20/41 (48%)
Query: 188 CLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVVGWHIQIH 228
CL+F PS + FL P+G SL +G+ + +H
Sbjct: 3 CLEFVPSDVRASPEFLPPSGFVVSLTSGVKLQTFAVSVTVH 43
>gi|116812584 SID1 transmembrane family, member 1 [Homo sapiens]
Length = 827
Score = 28.1 bits (61), Expect = 6.5
Identities = 15/65 (23%), Positives = 31/65 (47%), Gaps = 9/65 (13%)
Query: 61 FNGIVEENDSNIWKFWYTNQPPSKNCTHAYLSP------YPFM---RGEHNSTSYDSAVI 111
++G+V + NI+ F YT+QP Y++ YP + R + S+ ++
Sbjct: 52 YSGVVNLSTENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPVLVVVRQQKEVLSWQVPLL 111
Query: 112 YRGFW 116
++G +
Sbjct: 112 FQGLY 116
>gi|197276661 paired box 1 [Homo sapiens]
Length = 534
Score = 27.7 bits (60), Expect = 8.5
Identities = 13/30 (43%), Positives = 18/30 (60%), Gaps = 1/30 (3%)
Query: 129 IASFLIICAAPFAS-HFLYKAGGGSYIAAG 157
+ FL CA P ++ H +Y A GG Y+A G
Sbjct: 361 VGGFLPACAYPASNQHGVYSAPGGGYLAPG 390
>gi|22748765 claudin domain containing 2 [Homo sapiens]
Length = 167
Score = 27.7 bits (60), Expect = 8.5
Identities = 12/33 (36%), Positives = 19/33 (57%)
Query: 194 SVLYGWSFFLAPAGIFFSLLAGLLFLVVGWHIQ 226
+V + WS+F + FS+LAG FL+ +Q
Sbjct: 123 NVFFSWSYFSGWLALPFSILAGFCFLLADMIMQ 155
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.330 0.143 0.485
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,486,040
Number of Sequences: 37866
Number of extensions: 347878
Number of successful extensions: 1098
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1087
Number of HSP's gapped (non-prelim): 20
length of query: 229
length of database: 18,247,518
effective HSP length: 99
effective length of query: 130
effective length of database: 14,498,784
effective search space: 1884841920
effective search space used: 1884841920
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.