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Search of human proteins with 188497750
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188497750 hexokinase 1 isoform HKI-td [Homo sapiens]
(905 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188497750 hexokinase 1 isoform HKI-td [Homo sapiens] 1806 0.0
gi|188497754 hexokinase 1 isoform HKI [Homo sapiens] 1788 0.0
gi|15991829 hexokinase 1 isoform HKI-ta/tb [Homo sapiens] 1788 0.0
gi|15991831 hexokinase 1 isoform HKI-ta/tb [Homo sapiens] 1788 0.0
gi|15991827 hexokinase 1 isoform HKI-R [Homo sapiens] 1788 0.0
gi|15553127 hexokinase 2 [Homo sapiens] 1368 0.0
gi|156151420 hexokinase domain containing 1 [Homo sapiens] 1323 0.0
gi|194097330 hexokinase 3 [Homo sapiens] 945 0.0
gi|15967161 glucokinase isoform 3 [Homo sapiens] 506 e-143
gi|4503951 glucokinase isoform 1 [Homo sapiens] 504 e-142
gi|15967159 glucokinase isoform 2 [Homo sapiens] 503 e-142
gi|164663810 ribosomal modification protein rimK-like family mem... 35 0.41
gi|134254462 ribosomal modification protein rimK-like family mem... 33 0.92
gi|21389509 KPL2 protein isoform 2 [Homo sapiens] 32 2.7
gi|145699133 KPL2 protein isoform 1 [Homo sapiens] 32 2.7
gi|42415492 chromosome 14 open reading frame 106 [Homo sapiens] 30 7.8
>gi|188497750 hexokinase 1 isoform HKI-td [Homo sapiens]
Length = 905
Score = 1806 bits (4678), Expect = 0.0
Identities = 905/905 (100%), Positives = 905/905 (100%)
Query: 1 MAKRALHDFIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIP 60
MAKRALHDFIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIP
Sbjct: 1 MAKRALHDFIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIP 60
Query: 61 DGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAE 120
DGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAE
Sbjct: 61 DGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAE 120
Query: 121 CLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKA 180
CLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKA
Sbjct: 121 CLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKA 180
Query: 181 IKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDE 240
IKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDE
Sbjct: 181 IKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDE 240
Query: 241 GRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVK 300
GRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVK
Sbjct: 241 GRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVK 300
Query: 301 MAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQ 360
MAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQ
Sbjct: 301 MAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQ 360
Query: 361 HVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLR 420
HVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLR
Sbjct: 361 HVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLR 420
Query: 421 RLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMR 480
RLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMR
Sbjct: 421 RLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMR 480
Query: 481 AEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRT 540
AEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRT
Sbjct: 481 AEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRT 540
Query: 541 VEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLD 600
VEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLD
Sbjct: 541 VEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLD 600
Query: 601 AGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTC 660
AGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTC
Sbjct: 601 AGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTC 660
Query: 661 EVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEY 720
EVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEY
Sbjct: 661 EVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEY 720
Query: 721 SLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIES 780
SLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIES
Sbjct: 721 SLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIES 780
Query: 781 DRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLD 840
DRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLD
Sbjct: 781 DRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLD 840
Query: 841 RLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLR 900
RLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLR
Sbjct: 841 RLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLR 900
Query: 901 TEASS 905
TEASS
Sbjct: 901 TEASS 905
>gi|188497754 hexokinase 1 isoform HKI [Homo sapiens]
Length = 917
Score = 1788 bits (4631), Expect = 0.0
Identities = 896/896 (100%), Positives = 896/896 (100%)
Query: 10 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 69
IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI
Sbjct: 22 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 81
Query: 70 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 129
ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR
Sbjct: 82 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 141
Query: 130 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 189
KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA
Sbjct: 142 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 201
Query: 190 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 249
NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW
Sbjct: 202 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 261
Query: 250 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 309
GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE
Sbjct: 262 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 321
Query: 310 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 369
GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR
Sbjct: 322 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 381
Query: 370 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 429
SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR
Sbjct: 382 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 441
Query: 430 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK 489
FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK
Sbjct: 442 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK 501
Query: 490 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA 549
QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA
Sbjct: 502 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA 561
Query: 550 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK 609
IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK
Sbjct: 562 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK 621
Query: 610 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG 669
GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG
Sbjct: 622 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG 681
Query: 670 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY 729
SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY
Sbjct: 682 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY 741
Query: 730 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR 789
EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR
Sbjct: 742 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR 801
Query: 790 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD 849
AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD
Sbjct: 802 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD 861
Query: 850 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 905
GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS
Sbjct: 862 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 917
Score = 495 bits (1275), Expect = e-140
Identities = 235/447 (52%), Positives = 328/447 (73%)
Query: 453 EQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTE 512
+Q ++I++ L L+ + L+++ R R EM+ GL + + A VKMLP+FVR PDG+E
Sbjct: 17 DQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSE 76
Query: 513 NGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISD 572
GDF+ALDLGG++FR+L V++ K + V M +++Y P I+ G+G +LFDH+ C+ D
Sbjct: 77 KGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGD 136
Query: 573 FLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRR 632
F++ IK ++P+GFTFSFPCQQ+ +D ILITWTK FKA+ G DVV LL AIK+R
Sbjct: 137 FMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKR 196
Query: 633 EEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMC 692
++D ++VAVVNDTVGTMMTC Y++ CEVGLI+GTG+NACYMEE++++++VEGD+G+MC
Sbjct: 197 GDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMC 256
Query: 693 INMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKK 752
IN EWGAFGD+G L+DIRT +DR +D SLN GKQ +EKM+SGMYLGE+VR IL+ K+
Sbjct: 257 INTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKE 316
Query: 753 GFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCG 812
G LF G+I+ L TRG F T +S IE ++ L + IL +LG+ + DD + V+ VC
Sbjct: 317 GLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCT 376
Query: 813 VVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSP 872
+VS R+A L A + A+++++R+N+G RL TVGVDG+LYK HP +SR H+T++ L P
Sbjct: 377 IVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVP 436
Query: 873 KCNVSFLLSEDGSGKGAALITAVGVRL 899
+V FLLSE GSGKGAA++TAV RL
Sbjct: 437 DSDVRFLLSESGSGKGAAMVTAVAYRL 463
Score = 494 bits (1271), Expect = e-139
Identities = 235/445 (52%), Positives = 325/445 (73%)
Query: 7 HDFIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKG 66
H I++ L L+ + L+++ R R EM+ GL + + A VKMLP+FVR PDG+E G
Sbjct: 467 HRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENG 526
Query: 67 DFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFM 126
DF+ALDLGG++FR+L V++ K + V M +++Y P I+ G+G +LFDH+ C+ DF+
Sbjct: 527 DFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFL 586
Query: 127 EKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGD 186
+ IK ++P+GFTFSFPCQQ+ +D ILITWTK FKA+ G DVV LL AIK+R +
Sbjct: 587 DYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREE 646
Query: 187 YDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCIN 246
+D ++VAVVNDTVGTMMTC Y++ CEVGLI+GTG+NACYMEE++++++VEGD+G+MCIN
Sbjct: 647 FDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCIN 706
Query: 247 TEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGL 306
EWGAFGD+G L+DIRT +DR +D SLN GKQ +EKM+SGMYLGE+VR IL+ K+G
Sbjct: 707 MEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGF 766
Query: 307 LFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIV 366
LF G+I+ L TRG F T +S IE ++ L + IL +LG+ + DD + V+ VC +V
Sbjct: 767 LFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVV 826
Query: 367 SFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDS 426
S R+A L A + A+++++R+N+G RL TVGVDG+LYK HP +SR H+T++ L P
Sbjct: 827 SRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKC 886
Query: 427 DVRFLLSESGSGKGAAMVTAVAYRL 451
+V FLLSE GSGKGAA++TAV RL
Sbjct: 887 NVSFLLSEDGSGKGAALITAVGVRL 911
>gi|15991829 hexokinase 1 isoform HKI-ta/tb [Homo sapiens]
Length = 921
Score = 1788 bits (4631), Expect = 0.0
Identities = 896/896 (100%), Positives = 896/896 (100%)
Query: 10 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 69
IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI
Sbjct: 26 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 85
Query: 70 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 129
ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR
Sbjct: 86 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 145
Query: 130 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 189
KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA
Sbjct: 146 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 205
Query: 190 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 249
NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW
Sbjct: 206 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 265
Query: 250 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 309
GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE
Sbjct: 266 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 325
Query: 310 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 369
GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR
Sbjct: 326 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 385
Query: 370 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 429
SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR
Sbjct: 386 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 445
Query: 430 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK 489
FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK
Sbjct: 446 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK 505
Query: 490 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA 549
QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA
Sbjct: 506 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA 565
Query: 550 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK 609
IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK
Sbjct: 566 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK 625
Query: 610 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG 669
GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG
Sbjct: 626 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG 685
Query: 670 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY 729
SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY
Sbjct: 686 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY 745
Query: 730 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR 789
EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR
Sbjct: 746 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR 805
Query: 790 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD 849
AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD
Sbjct: 806 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD 865
Query: 850 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 905
GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS
Sbjct: 866 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 921
Score = 494 bits (1271), Expect = e-139
Identities = 235/445 (52%), Positives = 325/445 (73%)
Query: 7 HDFIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKG 66
H I++ L L+ + L+++ R R EM+ GL + + A VKMLP+FVR PDG+E G
Sbjct: 471 HRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENG 530
Query: 67 DFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFM 126
DF+ALDLGG++FR+L V++ K + V M +++Y P I+ G+G +LFDH+ C+ DF+
Sbjct: 531 DFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFL 590
Query: 127 EKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGD 186
+ IK ++P+GFTFSFPCQQ+ +D ILITWTK FKA+ G DVV LL AIK+R +
Sbjct: 591 DYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREE 650
Query: 187 YDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCIN 246
+D ++VAVVNDTVGTMMTC Y++ CEVGLI+GTG+NACYMEE++++++VEGD+G+MCIN
Sbjct: 651 FDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCIN 710
Query: 247 TEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGL 306
EWGAFGD+G L+DIRT +DR +D SLN GKQ +EKM+SGMYLGE+VR IL+ K+G
Sbjct: 711 MEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGF 770
Query: 307 LFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIV 366
LF G+I+ L TRG F T +S IE ++ L + IL +LG+ + DD + V+ VC +V
Sbjct: 771 LFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVV 830
Query: 367 SFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDS 426
S R+A L A + A+++++R+N+G RL TVGVDG+LYK HP +SR H+T++ L P
Sbjct: 831 SRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKC 890
Query: 427 DVRFLLSESGSGKGAAMVTAVAYRL 451
+V FLLSE GSGKGAA++TAV RL
Sbjct: 891 NVSFLLSEDGSGKGAALITAVGVRL 915
Score = 493 bits (1270), Expect = e-139
Identities = 234/443 (52%), Positives = 325/443 (73%)
Query: 457 QIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDF 516
+I++ L L+ + L+++ R R EM+ GL + + A VKMLP+FVR PDG+E GDF
Sbjct: 25 EIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDF 84
Query: 517 LALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDY 576
+ALDLGG++FR+L V++ K + V M +++Y P I+ G+G +LFDH+ C+ DF++
Sbjct: 85 IALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEK 144
Query: 577 MGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFD 636
IK ++P+GFTFSFPCQQ+ +D ILITWTK FKA+ G DVV LL AIK+R ++D
Sbjct: 145 RKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYD 204
Query: 637 LDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINME 696
++VAVVNDTVGTMMTC Y++ CEVGLI+GTG+NACYMEE++++++VEGD+G+MCIN E
Sbjct: 205 ANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTE 264
Query: 697 WGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLF 756
WGAFGD+G L+DIRT +DR +D SLN GKQ +EKM+SGMYLGE+VR IL+ K+G LF
Sbjct: 265 WGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLF 324
Query: 757 RGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSR 816
G+I+ L TRG F T +S IE ++ L + IL +LG+ + DD + V+ VC +VS
Sbjct: 325 EGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSF 384
Query: 817 RAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNV 876
R+A L A + A+++++R+N+G RL TVGVDG+LYK HP +SR H+T++ L P +V
Sbjct: 385 RSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDV 444
Query: 877 SFLLSEDGSGKGAALITAVGVRL 899
FLLSE GSGKGAA++TAV RL
Sbjct: 445 RFLLSESGSGKGAAMVTAVAYRL 467
>gi|15991831 hexokinase 1 isoform HKI-ta/tb [Homo sapiens]
Length = 921
Score = 1788 bits (4631), Expect = 0.0
Identities = 896/896 (100%), Positives = 896/896 (100%)
Query: 10 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 69
IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI
Sbjct: 26 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 85
Query: 70 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 129
ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR
Sbjct: 86 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 145
Query: 130 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 189
KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA
Sbjct: 146 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 205
Query: 190 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 249
NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW
Sbjct: 206 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 265
Query: 250 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 309
GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE
Sbjct: 266 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 325
Query: 310 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 369
GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR
Sbjct: 326 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 385
Query: 370 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 429
SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR
Sbjct: 386 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 445
Query: 430 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK 489
FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK
Sbjct: 446 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK 505
Query: 490 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA 549
QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA
Sbjct: 506 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA 565
Query: 550 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK 609
IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK
Sbjct: 566 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK 625
Query: 610 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG 669
GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG
Sbjct: 626 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG 685
Query: 670 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY 729
SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY
Sbjct: 686 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY 745
Query: 730 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR 789
EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR
Sbjct: 746 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR 805
Query: 790 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD 849
AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD
Sbjct: 806 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD 865
Query: 850 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 905
GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS
Sbjct: 866 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 921
Score = 494 bits (1271), Expect = e-139
Identities = 235/445 (52%), Positives = 325/445 (73%)
Query: 7 HDFIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKG 66
H I++ L L+ + L+++ R R EM+ GL + + A VKMLP+FVR PDG+E G
Sbjct: 471 HRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENG 530
Query: 67 DFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFM 126
DF+ALDLGG++FR+L V++ K + V M +++Y P I+ G+G +LFDH+ C+ DF+
Sbjct: 531 DFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFL 590
Query: 127 EKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGD 186
+ IK ++P+GFTFSFPCQQ+ +D ILITWTK FKA+ G DVV LL AIK+R +
Sbjct: 591 DYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREE 650
Query: 187 YDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCIN 246
+D ++VAVVNDTVGTMMTC Y++ CEVGLI+GTG+NACYMEE++++++VEGD+G+MCIN
Sbjct: 651 FDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCIN 710
Query: 247 TEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGL 306
EWGAFGD+G L+DIRT +DR +D SLN GKQ +EKM+SGMYLGE+VR IL+ K+G
Sbjct: 711 MEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGF 770
Query: 307 LFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIV 366
LF G+I+ L TRG F T +S IE ++ L + IL +LG+ + DD + V+ VC +V
Sbjct: 771 LFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVV 830
Query: 367 SFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDS 426
S R+A L A + A+++++R+N+G RL TVGVDG+LYK HP +SR H+T++ L P
Sbjct: 831 SRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKC 890
Query: 427 DVRFLLSESGSGKGAAMVTAVAYRL 451
+V FLLSE GSGKGAA++TAV RL
Sbjct: 891 NVSFLLSEDGSGKGAALITAVGVRL 915
Score = 493 bits (1270), Expect = e-139
Identities = 234/443 (52%), Positives = 325/443 (73%)
Query: 457 QIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDF 516
+I++ L L+ + L+++ R R EM+ GL + + A VKMLP+FVR PDG+E GDF
Sbjct: 25 EIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDF 84
Query: 517 LALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDY 576
+ALDLGG++FR+L V++ K + V M +++Y P I+ G+G +LFDH+ C+ DF++
Sbjct: 85 IALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEK 144
Query: 577 MGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFD 636
IK ++P+GFTFSFPCQQ+ +D ILITWTK FKA+ G DVV LL AIK+R ++D
Sbjct: 145 RKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYD 204
Query: 637 LDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINME 696
++VAVVNDTVGTMMTC Y++ CEVGLI+GTG+NACYMEE++++++VEGD+G+MCIN E
Sbjct: 205 ANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTE 264
Query: 697 WGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLF 756
WGAFGD+G L+DIRT +DR +D SLN GKQ +EKM+SGMYLGE+VR IL+ K+G LF
Sbjct: 265 WGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLF 324
Query: 757 RGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSR 816
G+I+ L TRG F T +S IE ++ L + IL +LG+ + DD + V+ VC +VS
Sbjct: 325 EGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSF 384
Query: 817 RAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNV 876
R+A L A + A+++++R+N+G RL TVGVDG+LYK HP +SR H+T++ L P +V
Sbjct: 385 RSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDV 444
Query: 877 SFLLSEDGSGKGAALITAVGVRL 899
FLLSE GSGKGAA++TAV RL
Sbjct: 445 RFLLSESGSGKGAAMVTAVAYRL 467
>gi|15991827 hexokinase 1 isoform HKI-R [Homo sapiens]
Length = 916
Score = 1788 bits (4631), Expect = 0.0
Identities = 896/896 (100%), Positives = 896/896 (100%)
Query: 10 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 69
IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI
Sbjct: 21 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 80
Query: 70 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 129
ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR
Sbjct: 81 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 140
Query: 130 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 189
KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA
Sbjct: 141 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 200
Query: 190 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 249
NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW
Sbjct: 201 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 260
Query: 250 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 309
GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE
Sbjct: 261 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 320
Query: 310 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 369
GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR
Sbjct: 321 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 380
Query: 370 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 429
SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR
Sbjct: 381 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 440
Query: 430 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK 489
FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK
Sbjct: 441 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK 500
Query: 490 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA 549
QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA
Sbjct: 501 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA 560
Query: 550 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK 609
IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK
Sbjct: 561 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK 620
Query: 610 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG 669
GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG
Sbjct: 621 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG 680
Query: 670 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY 729
SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY
Sbjct: 681 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY 740
Query: 730 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR 789
EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR
Sbjct: 741 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR 800
Query: 790 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD 849
AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD
Sbjct: 801 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD 860
Query: 850 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 905
GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS
Sbjct: 861 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 916
Score = 494 bits (1271), Expect = e-139
Identities = 235/445 (52%), Positives = 325/445 (73%)
Query: 7 HDFIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKG 66
H I++ L L+ + L+++ R R EM+ GL + + A VKMLP+FVR PDG+E G
Sbjct: 466 HRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENG 525
Query: 67 DFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFM 126
DF+ALDLGG++FR+L V++ K + V M +++Y P I+ G+G +LFDH+ C+ DF+
Sbjct: 526 DFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFL 585
Query: 127 EKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGD 186
+ IK ++P+GFTFSFPCQQ+ +D ILITWTK FKA+ G DVV LL AIK+R +
Sbjct: 586 DYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREE 645
Query: 187 YDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCIN 246
+D ++VAVVNDTVGTMMTC Y++ CEVGLI+GTG+NACYMEE++++++VEGD+G+MCIN
Sbjct: 646 FDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCIN 705
Query: 247 TEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGL 306
EWGAFGD+G L+DIRT +DR +D SLN GKQ +EKM+SGMYLGE+VR IL+ K+G
Sbjct: 706 MEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGF 765
Query: 307 LFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIV 366
LF G+I+ L TRG F T +S IE ++ L + IL +LG+ + DD + V+ VC +V
Sbjct: 766 LFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVV 825
Query: 367 SFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDS 426
S R+A L A + A+++++R+N+G RL TVGVDG+LYK HP +SR H+T++ L P
Sbjct: 826 SRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKC 885
Query: 427 DVRFLLSESGSGKGAAMVTAVAYRL 451
+V FLLSE GSGKGAA++TAV RL
Sbjct: 886 NVSFLLSEDGSGKGAALITAVGVRL 910
>gi|15553127 hexokinase 2 [Homo sapiens]
Length = 917
Score = 1368 bits (3542), Expect = 0.0
Identities = 658/891 (73%), Positives = 775/891 (86%)
Query: 10 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 69
+D+YLY MRLSDETL++I RFRKEM+ GL +PTA VKMLPTFVRS PDG+E G+F+
Sbjct: 22 VDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTEHGEFL 81
Query: 70 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 129
ALDLGG++FR+L V+V Q V ME+++Y PE+I+ GSG+QLFDH+AECL +FM+K
Sbjct: 82 ALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLANFMDKL 141
Query: 130 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 189
+IKDKKLP+GFTFSFPC Q+K+DE+ L++WTK FK+SGVEG DVV L+ KAI++RGD+D
Sbjct: 142 QIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQRRGDFDI 201
Query: 190 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 249
+IVAVVNDTVGTMMTCGYDD +CE+GLI+GTG+NACYMEE+RHID+VEGDEGRMCIN EW
Sbjct: 202 DIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEGDEGRMCINMEW 261
Query: 250 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 309
GAFGDDGSL DIRTEFD+EID GSLNPGKQLFEKM+SGMY+GELVRLILVKMAKE LLF
Sbjct: 262 GAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEELLFG 321
Query: 310 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 369
G+++PELL G+F T D+S IE K+G+ A+E+L RLG++P+ +DCV+ +C IVS R
Sbjct: 322 GKLSPELLNTGRFETKDISDIEGEKDGIRKAREVLMRLGLDPTQEDCVATHRICQIVSTR 381
Query: 370 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 429
SA+L AATL A+L R+++NKG RLR+T+GVDGS+YK HP +++R HKT+RRLVP DVR
Sbjct: 382 SASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKHPHFAKRLHKTVRRLVPGCDVR 441
Query: 430 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK 489
FL SE GSGKGAAMVTAVAYRLA+QHR ++TL H L+ D LLEVK+RM+ EME GL K
Sbjct: 442 FLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSK 501
Query: 490 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA 549
+TH +A VKMLP++V TPDGTE GDFLALDLGGTNFRVLLV++R+GK VEMHNKIYA
Sbjct: 502 ETHASAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYA 561
Query: 550 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK 609
IP E+M GTG+ELFDHIV CI+DFL+YMG+KG +PLGFTFSFPCQQ SLD IL+ WTK
Sbjct: 562 IPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTK 621
Query: 610 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG 669
GFKA+ C G DVVTLL++AI RREEFDLDVVAVVNDTVGTMMTC +E+P CEVGLIVGTG
Sbjct: 622 GFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTG 681
Query: 670 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY 729
SNACYMEEM+NVE+VEG++G+MC+NMEWGAFGDNGCLDD RT +D VDE SLN GKQR+
Sbjct: 682 SNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDDFRTEFDVAVDELSLNPGKQRF 741
Query: 730 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR 789
EKMISGMYLGEIVRNILIDFTK+G LFRG+ISE LKTRGIFETKFLSQIESD LALLQVR
Sbjct: 742 EKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLALLQVR 801
Query: 790 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD 849
AILQ LGL STCDDSI+VK VC VV+RRAAQLCGAGMAAVVD+IRENRGLD L VTVGVD
Sbjct: 802 AILQHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAAVVDRIRENRGLDALKVTVGVD 861
Query: 850 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLR 900
GTLYKLHPHF+++MH+TVK+L+PKC+VSFL SEDGSGKGAALITAV R+R
Sbjct: 862 GTLYKLHPHFAKVMHETVKDLAPKCDVSFLQSEDGSGKGAALITAVACRIR 912
Score = 546 bits (1406), Expect = e-155
Identities = 258/447 (57%), Positives = 344/447 (76%)
Query: 453 EQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTE 512
+Q +++++ L H L+ + LLE+ KR R EME GL TH A VKMLP+FVR TPDGTE
Sbjct: 17 DQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTE 76
Query: 513 NGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISD 572
+G+FLALDLGGTNFRVL VK+ + VEM N+IYAIP +IM+G+G +LFDHI C+++
Sbjct: 77 HGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 136
Query: 573 FLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRR 632
F+D + IK ++PLGFTFSFPC QT LD L++WTKGFK++ G DVV L+R AI+RR
Sbjct: 137 FMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQRR 196
Query: 633 EEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMC 692
+FD+D+VAVVNDTVGTMMTC Y++ CE+GLIVGTGSNACYMEEM++++MVEGD+G+MC
Sbjct: 197 GDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEGDEGRMC 256
Query: 693 INMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKK 752
INMEWGAFGD+G L+DIRT +D+ +D SLN GKQ +EKMISGMY+GE+VR IL+ K+
Sbjct: 257 INMEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKE 316
Query: 753 GFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCG 812
LF G++S L G FETK +S IE ++ + + R +L +LGL+ T +D + +C
Sbjct: 317 ELLFGGKLSPELLNTGRFETKDISDIEGEKDGIRKAREVLMRLGLDPTQEDCVATHRICQ 376
Query: 813 VVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSP 872
+VS R+A LC A +AAV+ +I+EN+G +RL T+GVDG++YK HPHF++ +H+TV+ L P
Sbjct: 377 IVSTRSASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKHPHFAKRLHKTVRRLVP 436
Query: 873 KCNVSFLLSEDGSGKGAALITAVGVRL 899
C+V FL SEDGSGKGAA++TAV RL
Sbjct: 437 GCDVRFLRSEDGSGKGAAMVTAVAYRL 463
Score = 521 bits (1343), Expect = e-148
Identities = 247/447 (55%), Positives = 337/447 (75%)
Query: 7 HDFIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKG 66
H K L ++LS + L+++ R + EM+ GLS++ + +A VKMLPT+V + PDG+EKG
Sbjct: 467 HRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKG 526
Query: 67 DFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFM 126
DF+ALDLGG++FR+L V+V + K V M +++Y P+ ++HG+G +LFDH+ +C+ DF+
Sbjct: 527 DFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFL 586
Query: 127 EKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGD 186
E +K LP+GFTFSFPCQQ+ +DE+IL+ WTK FKASG EG DVV LL +AI +R +
Sbjct: 587 EYMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREE 646
Query: 187 YDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCIN 246
+D ++VAVVNDTVGTMMTCG++D HCEVGLI+GTG+NACYMEE+R+++LVEG+EGRMC+N
Sbjct: 647 FDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVN 706
Query: 247 TEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGL 306
EWGAFGD+G L+D RTEFD +D SLNPGKQ FEKM+SGMYLGE+VR IL+ K GL
Sbjct: 707 MEWGAFGDNGCLDDFRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGL 766
Query: 307 LFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIV 366
LF GRI+ L TRG F T +S IE + L + IL LG+E + DD + V+ VCT+V
Sbjct: 767 LFRGRISERLKTRGIFETKFLSQIESDCLALLQVRAILQHLGLESTCDDSIIVKEVCTVV 826
Query: 367 SFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDS 426
+ R+A L A + A+++R+R+N+G L+ TVGVDG+LYK HP +++ H+T++ L P
Sbjct: 827 ARRAAQLCGAGMAAVVDRIRENRGLDALKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKC 886
Query: 427 DVRFLLSESGSGKGAAMVTAVAYRLAE 453
DV FL SE GSGKGAA++TAVA R+ E
Sbjct: 887 DVSFLQSEDGSGKGAALITAVACRIRE 913
>gi|156151420 hexokinase domain containing 1 [Homo sapiens]
Length = 917
Score = 1323 bits (3424), Expect = 0.0
Identities = 639/891 (71%), Positives = 764/891 (85%), Gaps = 1/891 (0%)
Query: 10 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 69
+D++LY MRLSD+TL+DIM RFR EM+ GL++D NPTA VKMLPTFVR+IPDGSE G+F+
Sbjct: 22 VDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEFL 81
Query: 70 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 129
+LDLGGS FR+L+VQV E ++V MES+ Y TP I+ G+G++LF++VA+CL DFM+ +
Sbjct: 82 SLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMKTK 141
Query: 130 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 189
+K KKLP+G TFSFPC+Q+K++E +L++WTK+FKA GV+ DVV L KA+++ D D
Sbjct: 142 DLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKDMDV 201
Query: 190 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 249
+I+A+VNDTVGTMMTC YDD +CEVG+IIGTGTNACYME++ +IDLVEGDEGRMCINTEW
Sbjct: 202 DILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMCINTEW 261
Query: 250 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 309
GAFGDDG+LEDIRTEFDRE+D GSLNPGKQLFEKM+SG+YLGELVRLIL+KMAK GLLF
Sbjct: 262 GAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGLLFG 321
Query: 310 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 369
G + L T+GK T V+A+EK KEGL N +EIL LG+EPS+ DC++VQHVCTIVSFR
Sbjct: 322 GEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHVCTIVSFR 381
Query: 370 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 429
SANL AA L AIL RLR+NK RLRTTVG+DG+LYK HPQY +R HK +R+LVP DVR
Sbjct: 382 SANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVPSCDVR 441
Query: 430 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK 489
FLLSESGS KGAAMVTAVA R+ Q +QI+ LA F LT++ L++V+ +MRAE+E GL+K
Sbjct: 442 FLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLKK 501
Query: 490 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA 549
++H A V+MLP++V PDGTE G FLALDLGGTNFRVLLVKIRSG +R+V M+NKI+A
Sbjct: 502 KSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRVLLVKIRSG-RRSVRMYNKIFA 560
Query: 550 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK 609
IP+EIMQGTGEELFDHIV CI+DFLDYMG+KG +PLGFTFSFPC+Q S+D G LI WTK
Sbjct: 561 IPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLIGWTK 620
Query: 610 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG 669
GFKATDC G DVV +LR+AIKRR EFDLD+VAVVNDTVGTMMTC YE+P CE+GLI GTG
Sbjct: 621 GFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTG 680
Query: 670 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY 729
SN CYME+M+N+EMVEG +G+MCIN EWG FGDNGC+DDIRT YD VDE SLN GKQRY
Sbjct: 681 SNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRY 740
Query: 730 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR 789
EKM SGMYLGEIVR ILID TK+G LFRGQISE L+TRGIFETKFLSQIESDRLALLQVR
Sbjct: 741 EKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQVR 800
Query: 790 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD 849
ILQQLGL+STC+DSI+VK VCG VSRRAAQLCGAG+AA+V+K RE++GL+ L +TVGVD
Sbjct: 801 RILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVD 860
Query: 850 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLR 900
GTLYKLHPHFSRI+ +TVKEL+P+C+V+F+LSEDGSGKGAALITAV RL+
Sbjct: 861 GTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGAALITAVAKRLQ 911
Score = 498 bits (1282), Expect = e-140
Identities = 235/450 (52%), Positives = 332/450 (73%)
Query: 453 EQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTE 512
+Q ++++ L H L+ D LL++ +R RAEME GL K T+ A VKMLP+FVR PDG+E
Sbjct: 17 DQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSE 76
Query: 513 NGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISD 572
NG+FL+LDLGG+ FRVL V++ KR V+M ++ Y P EI++G G ELF+++ C++D
Sbjct: 77 NGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLAD 136
Query: 573 FLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRR 632
F+ +K ++PLG TFSFPC+QT L+ G+L++WTK FKA DVV+ L A++R
Sbjct: 137 FMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRH 196
Query: 633 EEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMC 692
++ D+D++A+VNDTVGTMMTCAY++P CEVG+I+GTG+NACYME+M N+++VEGD+G+MC
Sbjct: 197 KDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMC 256
Query: 693 INMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKK 752
IN EWGAFGD+G L+DIRT +DR +D SLN GKQ +EKMISG+YLGE+VR IL+ K
Sbjct: 257 INTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKA 316
Query: 753 GFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCG 812
G LF G+ S L T+G ET+ ++ +E + L R IL LGL + D I V+ VC
Sbjct: 317 GLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHVCT 376
Query: 813 VVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSP 872
+VS R+A LC A +AA++ ++REN+ ++RL TVG+DGTLYK+HP + + +H+ V++L P
Sbjct: 377 IVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVP 436
Query: 873 KCNVSFLLSEDGSGKGAALITAVGVRLRTE 902
C+V FLLSE GS KGAA++TAV R++ +
Sbjct: 437 SCDVRFLLSESGSTKGAAMVTAVASRVQAQ 466
Score = 493 bits (1270), Expect = e-139
Identities = 234/448 (52%), Positives = 330/448 (73%), Gaps = 1/448 (0%)
Query: 10 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 69
ID+ L +L+ E L+D+ + R E++ GL + + ATV+MLPT+V +PDG+EKG F+
Sbjct: 470 IDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFL 529
Query: 70 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 129
ALDLGG++FR+L V++ + ++V M ++++ P I+ G+G +LFDH+ +C+ DF++
Sbjct: 530 ALDLGGTNFRVLLVKIRSGR-RSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYM 588
Query: 130 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 189
+K LP+GFTFSFPC+Q ID+ LI WTK FKA+ EG DVV +L +AIK+R ++D
Sbjct: 589 GLKGASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDL 648
Query: 190 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 249
+IVAVVNDTVGTMMTCGY+D +CE+GLI GTG+N CYME++R+I++VEG EG+MCINTEW
Sbjct: 649 DIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEW 708
Query: 250 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 309
G FGD+G ++DIRT +D E+D GSLNPGKQ +EKM SGMYLGE+VR IL+ + K+GLLF
Sbjct: 709 GGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFR 768
Query: 310 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 369
G+I+ L TRG F T +S IE ++ L + IL +LG++ + +D + V+ VC VS R
Sbjct: 769 GQISERLRTRGIFETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRR 828
Query: 370 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 429
+A L A L AI+ + R+++G LR TVGVDG+LYK HP +SR +T++ L P DV
Sbjct: 829 AAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVT 888
Query: 430 FLLSESGSGKGAAMVTAVAYRLAEQHRQ 457
F+LSE GSGKGAA++TAVA RL + ++
Sbjct: 889 FMLSEDGSGKGAALITAVAKRLQQAQKE 916
>gi|194097330 hexokinase 3 [Homo sapiens]
Length = 923
Score = 945 bits (2442), Expect = 0.0
Identities = 478/894 (53%), Positives = 630/894 (70%), Gaps = 9/894 (1%)
Query: 8 DFIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGD 67
+ + + L +++ L I M+ L +P V+MLPT+V S P G+E+GD
Sbjct: 31 ELVQECLQQFKVTRAQLQQIQASLLGSMEQALRGQASPAPAVRMLPTYVGSTPHGTEQGD 90
Query: 68 FIALDLG--GSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDF 125
F+ L+LG G+S R+L V + + V S+ + P+ ++ G+G QLFD A CL +F
Sbjct: 91 FVVLELGATGASLRVLWVTLTGIEGHRVEPRSQEFVIPQEVMLGAGQQLFDFAAHCLSEF 150
Query: 126 MEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRG 185
++ + + + L +GF+FSFPC Q+ +D + LI+WTK F+ SGVEG DVV+LL AI+++G
Sbjct: 151 LDAQPVNKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIRRQG 210
Query: 186 DYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCI 245
Y+ ++VAVVNDTVGTMM C + CEVGL++ TGTNACYMEE RH+ +++ D GR+C+
Sbjct: 211 AYNIDVVAVVNDTVGTMMGCEPGVRPCEVGLVVDTGTNACYMEEARHVAVLDEDRGRVCV 270
Query: 246 NTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEG 305
+ EWG+F DDG+L + T FD +D SLNPG Q FEKM+ G+YLGELVRL+L +A+ G
Sbjct: 271 SVEWGSFSDDGALGPVLTTFDHTLDHESLNPGAQRFEKMIGGLYLGELVRLVLAHLARCG 330
Query: 306 LLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTI 365
+LF G +P LL++G V+ +E G IL LG+ P D VQHVC
Sbjct: 331 VLFGGCTSPALLSQGSILLEHVAEMEDPSTGAARVHAILQDLGLSPGASDVELVQHVCAA 390
Query: 366 VSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPD 425
V R+A L AA L A+L+ L+ ++ L+ V G + + HP++ T+ L P+
Sbjct: 391 VCTRAAQLCAAALAAVLSCLQHSREQQTLQVAVATGGRVCERHPRFCSVLQGTVMLLAPE 450
Query: 426 SDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMEL 485
DV + S G G+G AMVTAVA RLA R +EETLA F L D L V+ +MR M
Sbjct: 451 CDVSLIPSVDGGGRGVAMVTAVAARLAAHRRLLEETLAPFRLNHDQLAAVQAQMRKAMAK 510
Query: 486 GLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHN 545
GLR + + ++MLP+FVR TPDG+E GDFLALDLGGTNFRVLLV++ +G V++ +
Sbjct: 511 GLRGEASS---LRMLPTFVRATPDGSERGDFLALDLGGTNFRVLLVRVTTG----VQITS 563
Query: 546 KIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILI 605
+IY+IP + QG+G++LFDHIV CI DF G+ G +PLGFTFSFPC+Q LD GIL+
Sbjct: 564 EIYSIPETVAQGSGQQLFDHIVDCIVDFQQKQGLSGQSLPLGFTFSFPCRQLGLDQGILL 623
Query: 606 TWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLI 665
WTKGFKA+DC G DVV+LLR+AI RR+ +L+VVA+VNDTVGTMM+C YE+P CE+GLI
Sbjct: 624 NWTKGFKASDCEGQDVVSLLREAITRRQAVELNVVAIVNDTVGTMMSCGYEDPRCEIGLI 683
Query: 666 VGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAG 725
VGTG+NACYMEE++NV V GD G+MCINMEWGAFGD+G L + T +D VD+ S+N G
Sbjct: 684 VGTGTNACYMEELRNVAGVPGDSGRMCINMEWGAFGDDGSLAMLSTRFDASVDQASINPG 743
Query: 726 KQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLAL 785
KQR+EKMISGMYLGEIVR+IL+ T G LFRGQ + L+TR IF+TKFLS+IESD LAL
Sbjct: 744 KQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQQIQRLQTRDIFKTKFLSEIESDSLAL 803
Query: 786 LQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVT 845
QVRAIL+ LGL T DD+++V VC VS+RAAQLCGAG+AAVV+KIRENRGL+ L V+
Sbjct: 804 RQVRAILEDLGLPLTSDDALMVLEVCQAVSQRAAQLCGAGVAAVVEKIRENRGLEELAVS 863
Query: 846 VGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRL 899
VGVDGTLYKLHP FS ++ TV+EL+P+C V+FL SEDGSGKGAAL+TAV RL
Sbjct: 864 VGVDGTLYKLHPRFSSLVAATVRELAPRCVVTFLQSEDGSGKGAALVTAVACRL 917
Score = 464 bits (1193), Expect = e-130
Identities = 235/456 (51%), Positives = 312/456 (68%), Gaps = 8/456 (1%)
Query: 2 AKRALHD-FIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIP 60
A+ A H +++ L RL+ + L + + RK M GL + ++++MLPTFVR+ P
Sbjct: 474 ARLAAHRRLLEETLAPFRLNHDQLAAVQAQMRKAMAKGLRGE---ASSLRMLPTFVRATP 530
Query: 61 DGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAE 120
DGSE+GDF+ALDLGG++FR+L V+V V + SE+Y PE + GSG QLFDH+ +
Sbjct: 531 DGSERGDFLALDLGGTNFRVLLVRVT----TGVQITSEIYSIPETVAQGSGQQLFDHIVD 586
Query: 121 CLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKA 180
C+ DF +K+ + + LP+GFTFSFPC+Q +D+ IL+ WTK FKAS EG DVV LL +A
Sbjct: 587 CIVDFQQKQGLSGQSLPLGFTFSFPCRQLGLDQGILLNWTKGFKASDCEGQDVVSLLREA 646
Query: 181 IKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDE 240
I +R + N+VA+VNDTVGTMM+CGY+D CE+GLI+GTGTNACYMEELR++ V GD
Sbjct: 647 ITRRQAVELNVVAIVNDTVGTMMSCGYEDPRCEIGLIVGTGTNACYMEELRNVAGVPGDS 706
Query: 241 GRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVK 300
GRMCIN EWGAFGDDGSL + T FD +D+ S+NPGKQ FEKM+SGMYLGE+VR IL+
Sbjct: 707 GRMCINMEWGAFGDDGSLAMLSTRFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLH 766
Query: 301 MAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQ 360
+ G+LF G+ L TR F T +S IE + L + IL LG+ + DD + V
Sbjct: 767 LTSLGVLFRGQQIQRLQTRDIFKTKFLSEIESDSLALRQVRAILEDLGLPLTSDDALMVL 826
Query: 361 HVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLR 420
VC VS R+A L A + A++ ++R+N+G L +VGVDG+LYK HP++S T+R
Sbjct: 827 EVCQAVSQRAAQLCGAGVAAVVEKIRENRGLEELAVSVGVDGTLYKLHPRFSSLVAATVR 886
Query: 421 RLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHR 456
L P V FL SE GSGKGAA+VTAVA RLA+ R
Sbjct: 887 ELAPRCVVTFLQSEDGSGKGAALVTAVACRLAQLTR 922
>gi|15967161 glucokinase isoform 3 [Homo sapiens]
Length = 464
Score = 506 bits (1304), Expect = e-143
Identities = 245/451 (54%), Positives = 336/451 (74%), Gaps = 2/451 (0%)
Query: 450 RLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPD 509
+L + + Q+E+ LA F L ++ L +V +RM+ EM+ GLR +TH A VKMLP++VR TP+
Sbjct: 7 QLPQPNSQVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPE 66
Query: 510 GTENGDFLALDLGGTNFRVLLVKIRSGKKR--TVEMHNKIYAIPIEIMQGTGEELFDHIV 567
G+E GDFL+LDLGGTNFRV+LVK+ G++ +V+ +++Y+IP + M GT E LFD+I
Sbjct: 67 GSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYIS 126
Query: 568 SCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRD 627
CISDFLD +K ++PLGFTFSFP + +D GIL+ WTKGFKA+ G++VV LLRD
Sbjct: 127 ECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRD 186
Query: 628 AIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGD 687
AIKRR +F++DVVA+VNDTV TM++C YE+ CEVG+IVGTG NACYMEEM+NVE+VEGD
Sbjct: 187 AIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGD 246
Query: 688 QGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILI 747
+G+MC+N EWGAFGD+G LD+ YDRLVDE S N G+Q YEK+I G Y+GE+VR +L+
Sbjct: 247 EGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLL 306
Query: 748 DFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILV 807
+ LF G+ SE L+TRG FET+F+SQ+ESD Q+ IL LGL + D +V
Sbjct: 307 RLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIV 366
Query: 808 KTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTV 867
+ C VS RAA +C AG+A V++++RE+R D + +TVGVDG++YKLHP F H +V
Sbjct: 367 RRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASV 426
Query: 868 KELSPKCNVSFLLSEDGSGKGAALITAVGVR 898
+ L+P C ++F+ SE+GSG+GAAL++AV +
Sbjct: 427 RRLTPSCEITFIESEEGSGRGAALVSAVACK 457
Score = 474 bits (1219), Expect = e-133
Identities = 222/445 (49%), Positives = 320/445 (71%), Gaps = 2/445 (0%)
Query: 10 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 69
+++ L +L +E L +M R +KEM GL + + A+VKMLPT+VRS P+GSE GDF+
Sbjct: 15 VEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFL 74
Query: 70 ALDLGGSSFRILRVQVNH--EKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFME 127
+LDLGG++FR++ V+V E +V + ++Y PE+ + G+ LFD+++EC+ DF++
Sbjct: 75 SLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLD 134
Query: 128 KRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDY 187
K ++K KKLP+GFTFSFP + ID+ IL+ WTK FKASG EG +VV LL AIK+RGD+
Sbjct: 135 KHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDF 194
Query: 188 DANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINT 247
+ ++VA+VNDTV TM++C Y+D CEVG+I+GTG NACYMEE+++++LVEGDEGRMC+NT
Sbjct: 195 EMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNT 254
Query: 248 EWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLL 307
EWGAFGD G L++ E+DR +D S NPG+QL+EK++ G Y+GELVRL+L+++ E LL
Sbjct: 255 EWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLL 314
Query: 308 FEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVS 367
F G + +L TRG F T VS +E + IL+ LG+ PS DC V+ C VS
Sbjct: 315 FHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVS 374
Query: 368 FRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSD 427
R+A++ +A L ++NR+R+++ +R TVGVDGS+YK HP + RFH ++RRL P +
Sbjct: 375 TRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCE 434
Query: 428 VRFLLSESGSGKGAAMVTAVAYRLA 452
+ F+ SE GSG+GAA+V+AVA + A
Sbjct: 435 ITFIESEEGSGRGAALVSAVACKKA 459
>gi|4503951 glucokinase isoform 1 [Homo sapiens]
Length = 465
Score = 504 bits (1298), Expect = e-142
Identities = 244/449 (54%), Positives = 334/449 (74%), Gaps = 2/449 (0%)
Query: 452 AEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGT 511
A + ++E+ LA F L ++ L +V +RM+ EM+ GLR +TH A VKMLP++VR TP+G+
Sbjct: 10 AAKKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGS 69
Query: 512 ENGDFLALDLGGTNFRVLLVKIRSGKKR--TVEMHNKIYAIPIEIMQGTGEELFDHIVSC 569
E GDFL+LDLGGTNFRV+LVK+ G++ +V+ +++Y+IP + M GT E LFD+I C
Sbjct: 70 EVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISEC 129
Query: 570 ISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAI 629
ISDFLD +K ++PLGFTFSFP + +D GIL+ WTKGFKA+ G++VV LLRDAI
Sbjct: 130 ISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAI 189
Query: 630 KRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQG 689
KRR +F++DVVA+VNDTV TM++C YE+ CEVG+IVGTG NACYMEEM+NVE+VEGD+G
Sbjct: 190 KRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEG 249
Query: 690 QMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDF 749
+MC+N EWGAFGD+G LD+ YDRLVDE S N G+Q YEK+I G Y+GE+VR +L+
Sbjct: 250 RMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRL 309
Query: 750 TKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKT 809
+ LF G+ SE L+TRG FET+F+SQ+ESD Q+ IL LGL + D +V+
Sbjct: 310 VDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRR 369
Query: 810 VCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKE 869
C VS RAA +C AG+A V++++RE+R D + +TVGVDG++YKLHP F H +V+
Sbjct: 370 ACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRR 429
Query: 870 LSPKCNVSFLLSEDGSGKGAALITAVGVR 898
L+P C ++F+ SE+GSG+GAAL++AV +
Sbjct: 430 LTPSCEITFIESEEGSGRGAALVSAVACK 458
Score = 474 bits (1219), Expect = e-133
Identities = 222/445 (49%), Positives = 320/445 (71%), Gaps = 2/445 (0%)
Query: 10 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 69
+++ L +L +E L +M R +KEM GL + + A+VKMLPT+VRS P+GSE GDF+
Sbjct: 16 VEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFL 75
Query: 70 ALDLGGSSFRILRVQVNH--EKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFME 127
+LDLGG++FR++ V+V E +V + ++Y PE+ + G+ LFD+++EC+ DF++
Sbjct: 76 SLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLD 135
Query: 128 KRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDY 187
K ++K KKLP+GFTFSFP + ID+ IL+ WTK FKASG EG +VV LL AIK+RGD+
Sbjct: 136 KHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDF 195
Query: 188 DANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINT 247
+ ++VA+VNDTV TM++C Y+D CEVG+I+GTG NACYMEE+++++LVEGDEGRMC+NT
Sbjct: 196 EMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNT 255
Query: 248 EWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLL 307
EWGAFGD G L++ E+DR +D S NPG+QL+EK++ G Y+GELVRL+L+++ E LL
Sbjct: 256 EWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLL 315
Query: 308 FEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVS 367
F G + +L TRG F T VS +E + IL+ LG+ PS DC V+ C VS
Sbjct: 316 FHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVS 375
Query: 368 FRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSD 427
R+A++ +A L ++NR+R+++ +R TVGVDGS+YK HP + RFH ++RRL P +
Sbjct: 376 TRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCE 435
Query: 428 VRFLLSESGSGKGAAMVTAVAYRLA 452
+ F+ SE GSG+GAA+V+AVA + A
Sbjct: 436 ITFIESEEGSGRGAALVSAVACKKA 460
>gi|15967159 glucokinase isoform 2 [Homo sapiens]
Length = 466
Score = 503 bits (1294), Expect = e-142
Identities = 243/443 (54%), Positives = 331/443 (74%), Gaps = 2/443 (0%)
Query: 458 IEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFL 517
+E+ LA F L ++ L +V +RM+ EM+ GLR +TH A VKMLP++VR TP+G+E GDFL
Sbjct: 17 VEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFL 76
Query: 518 ALDLGGTNFRVLLVKIRSGKKR--TVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 575
+LDLGGTNFRV+LVK+ G++ +V+ +++Y+IP + M GT E LFD+I CISDFLD
Sbjct: 77 SLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLD 136
Query: 576 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEF 635
+K ++PLGFTFSFP + +D GIL+ WTKGFKA+ G++VV LLRDAIKRR +F
Sbjct: 137 KHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDF 196
Query: 636 DLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINM 695
++DVVA+VNDTV TM++C YE+ CEVG+IVGTG NACYMEEM+NVE+VEGD+G+MC+N
Sbjct: 197 EMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNT 256
Query: 696 EWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFL 755
EWGAFGD+G LD+ YDRLVDE S N G+Q YEK+I G Y+GE+VR +L+ + L
Sbjct: 257 EWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLL 316
Query: 756 FRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVS 815
F G+ SE L+TRG FET+F+SQ+ESD Q+ IL LGL + D +V+ C VS
Sbjct: 317 FHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVS 376
Query: 816 RRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCN 875
RAA +C AG+A V++++RE+R D + +TVGVDG++YKLHP F H +V+ L+P C
Sbjct: 377 TRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCE 436
Query: 876 VSFLLSEDGSGKGAALITAVGVR 898
++F+ SE+GSG+GAAL++AV +
Sbjct: 437 ITFIESEEGSGRGAALVSAVACK 459
Score = 474 bits (1219), Expect = e-133
Identities = 222/445 (49%), Positives = 320/445 (71%), Gaps = 2/445 (0%)
Query: 10 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 69
+++ L +L +E L +M R +KEM GL + + A+VKMLPT+VRS P+GSE GDF+
Sbjct: 17 VEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFL 76
Query: 70 ALDLGGSSFRILRVQVNH--EKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFME 127
+LDLGG++FR++ V+V E +V + ++Y PE+ + G+ LFD+++EC+ DF++
Sbjct: 77 SLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLD 136
Query: 128 KRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDY 187
K ++K KKLP+GFTFSFP + ID+ IL+ WTK FKASG EG +VV LL AIK+RGD+
Sbjct: 137 KHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDF 196
Query: 188 DANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINT 247
+ ++VA+VNDTV TM++C Y+D CEVG+I+GTG NACYMEE+++++LVEGDEGRMC+NT
Sbjct: 197 EMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNT 256
Query: 248 EWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLL 307
EWGAFGD G L++ E+DR +D S NPG+QL+EK++ G Y+GELVRL+L+++ E LL
Sbjct: 257 EWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLL 316
Query: 308 FEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVS 367
F G + +L TRG F T VS +E + IL+ LG+ PS DC V+ C VS
Sbjct: 317 FHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVS 376
Query: 368 FRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSD 427
R+A++ +A L ++NR+R+++ +R TVGVDGS+YK HP + RFH ++RRL P +
Sbjct: 377 TRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCE 436
Query: 428 VRFLLSESGSGKGAAMVTAVAYRLA 452
+ F+ SE GSG+GAA+V+AVA + A
Sbjct: 437 ITFIESEEGSGRGAALVSAVACKKA 461
>gi|164663810 ribosomal modification protein rimK-like family member
A [Homo sapiens]
Length = 391
Score = 34.7 bits (78), Expect = 0.41
Identities = 33/143 (23%), Positives = 59/143 (41%), Gaps = 30/143 (20%)
Query: 566 IVSCISDFLDYMGIKGPRMPLGFTFSFPCQQT---------SLDAGILITWTKG------ 610
I++CI+ F + + G +P+ TFS+ + L +++ T+G
Sbjct: 105 ILNCINKFWTFQELAGHGVPMPDTFSYGGHEDFSKMIDEAEPLGYPVVVKSTRGHRGKAV 164
Query: 611 FKATD---------CVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYE---EP 658
F A D + HDV L + +K D+ VV V +G+M+ C+ + +
Sbjct: 165 FLARDKHHLSDICHLIRHDVPYLFQKYVKESHGKDIRVVVVGGQVIGSMLRCSTDGRMQS 224
Query: 659 TCEVGLIVGTGSNACYMEEMKNV 681
C +G G G E+ K +
Sbjct: 225 NCSLG---GVGVKCPLTEQGKQL 244
>gi|134254462 ribosomal modification protein rimK-like family member
B [Homo sapiens]
Length = 386
Score = 33.5 bits (75), Expect = 0.92
Identities = 41/191 (21%), Positives = 75/191 (39%), Gaps = 51/191 (26%)
Query: 566 IVSCISDFLDYMGIKGPRMPLGFTFSFPCQQT---------SLDAGILITWTKG------ 610
I++C++ F + + G +PL TFS+ + L+ +++ T+G
Sbjct: 109 ILNCVNKFWTFQELAGHGVPLPDTFSYGGHENFAKMIDEAEVLEFPMVVKNTRGHRGKAV 168
Query: 611 FKATD---------CVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYE---EP 658
F A D + H+ L + +K D+ V+ V VGTM+ C+ + +
Sbjct: 169 FLARDKHHLADLSHLIRHEAPYLFQKYVKESHGRDVRVIVVGGRVVGTMLRCSTDGRMQS 228
Query: 659 TCEVGLIVGTGSNACYMEEMK---------------NVEMVEGDQGQMCI-----NMEWG 698
C +G G G E+ K ++++ D G C+ N+ +
Sbjct: 229 NCSLG---GVGMMCSLSEQGKQLAIQVSNILGMDVCGIDLLMKDDGSFCVCEANANVGFI 285
Query: 699 AFGDNGCLDDI 709
AF D C D+
Sbjct: 286 AF-DKACNLDV 295
>gi|21389509 KPL2 protein isoform 2 [Homo sapiens]
Length = 514
Score = 32.0 bits (71), Expect = 2.7
Identities = 17/76 (22%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Query: 447 VAYRLAEQHRQIEETLAHFHLTK-DMLLEVKKRMRA-EMELGLRKQTHNNAVVKMLPSFV 504
+ YR E+++ ++E LAH H K + ++K+ R ++E + N ++ + + +
Sbjct: 155 ITYRFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAI 214
Query: 505 RRTPDGTENGDFLALD 520
+ P N AL+
Sbjct: 215 IQIPKPASNRTLKALE 230
>gi|145699133 KPL2 protein isoform 1 [Homo sapiens]
Length = 1822
Score = 32.0 bits (71), Expect = 2.7
Identities = 17/76 (22%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Query: 447 VAYRLAEQHRQIEETLAHFHLTK-DMLLEVKKRMRA-EMELGLRKQTHNNAVVKMLPSFV 504
+ YR E+++ ++E LAH H K + ++K+ R ++E + N ++ + + +
Sbjct: 155 ITYRFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAI 214
Query: 505 RRTPDGTENGDFLALD 520
+ P N AL+
Sbjct: 215 IQIPKPASNRTLKALE 230
>gi|42415492 chromosome 14 open reading frame 106 [Homo sapiens]
Length = 1132
Score = 30.4 bits (67), Expect = 7.8
Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 4/77 (5%)
Query: 265 FDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMA--KEGLLFEGRITPELLTRGKF 322
F I G+L P K L + S + L + + +KM +F+ + E T
Sbjct: 30 FFDSIPSGTLTPVKDLVKYQNSSLKLNDHKKNQFLKMTTFNNKNIFQSTMLTEATTSN-- 87
Query: 323 NTSDVSAIEKNKEGLHN 339
++ D+SAI+ NK+GL N
Sbjct: 88 SSLDISAIKPNKDGLKN 104
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,753,823
Number of Sequences: 37866
Number of extensions: 1385141
Number of successful extensions: 2728
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2683
Number of HSP's gapped (non-prelim): 33
length of query: 905
length of database: 18,247,518
effective HSP length: 111
effective length of query: 794
effective length of database: 14,044,392
effective search space: 11151247248
effective search space used: 11151247248
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.