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Search of human proteins with 188497623
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188497623 neuromedin U receptor 1 [Homo sapiens]
(426 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188497623 neuromedin U receptor 1 [Homo sapiens] 872 0.0
gi|170932505 neuromedin U receptor 2 [Homo sapiens] 362 e-100
gi|110611243 neurotensin receptor 1 [Homo sapiens] 179 3e-45
gi|4504095 motilin receptor [Homo sapiens] 174 1e-43
gi|38455410 growth hormone secretagogue receptor isoform 1a [Hom... 167 2e-41
gi|6912538 neurotensin receptor 2 [Homo sapiens] 160 3e-39
gi|149944554 somatostatin receptor 4 [Homo sapiens] 140 3e-33
gi|63477962 opioid receptor, delta 1 [Homo sapiens] 130 2e-30
gi|4507681 thyrotropin-releasing hormone receptor [Homo sapiens] 125 6e-29
gi|157738685 G protein-coupled receptor 103 [Homo sapiens] 124 1e-28
gi|4557865 somatostatin receptor 5 [Homo sapiens] 123 3e-28
gi|7669548 tachykinin receptor 3 [Homo sapiens] 123 3e-28
gi|4557861 somatostatin receptor 3 [Homo sapiens] 122 6e-28
gi|4557857 somatostatin receptor 1 [Homo sapiens] 122 8e-28
gi|4505513 opiate receptor-like 1 [Homo sapiens] 122 8e-28
gi|33286424 opiate receptor-like 1 [Homo sapiens] 122 8e-28
gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens] 121 1e-27
gi|4557859 somatostatin receptor 2 [Homo sapiens] 121 1e-27
gi|4758434 growth hormone secretagogue receptor isoform 1b [Homo... 120 2e-27
gi|157426873 tachykinin receptor 2 [Homo sapiens] 119 4e-27
gi|39725940 opioid receptor, kappa 1 [Homo sapiens] 119 5e-27
gi|222080095 orexin receptor 1 [Homo sapiens] 118 1e-26
gi|4502455 bombesin-like receptor 3 [Homo sapiens] 116 4e-26
gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens] 114 2e-25
gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens] 113 3e-25
gi|222080109 orexin receptor 2 [Homo sapiens] 110 2e-24
gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens] 110 3e-24
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens] 109 4e-24
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens] 109 4e-24
gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens] 109 4e-24
>gi|188497623 neuromedin U receptor 1 [Homo sapiens]
Length = 426
Score = 872 bits (2252), Expect = 0.0
Identities = 426/426 (100%), Positives = 426/426 (100%)
Query: 1 MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELF 60
MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELF
Sbjct: 1 MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELF 60
Query: 61 MPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE 120
MPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE
Sbjct: 61 MPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE 120
Query: 121 MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRR 180
MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRR
Sbjct: 121 MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRR 180
Query: 181 VLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFF 240
VLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFF
Sbjct: 181 VLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFF 240
Query: 241 CLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLF 300
CLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLF
Sbjct: 241 CLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLF 300
Query: 301 VLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMS 360
VLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMS
Sbjct: 301 VLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMS 360
Query: 361 SRFRETFQEALCLGACCHRLRPRHSSHSLSRMTTGSTLCDVGSLGSWVHPLAGNDGPEAQ 420
SRFRETFQEALCLGACCHRLRPRHSSHSLSRMTTGSTLCDVGSLGSWVHPLAGNDGPEAQ
Sbjct: 361 SRFRETFQEALCLGACCHRLRPRHSSHSLSRMTTGSTLCDVGSLGSWVHPLAGNDGPEAQ 420
Query: 421 QETDPS 426
QETDPS
Sbjct: 421 QETDPS 426
>gi|170932505 neuromedin U receptor 2 [Homo sapiens]
Length = 415
Score = 362 bits (928), Expect = e-100
Identities = 174/332 (52%), Positives = 234/332 (70%), Gaps = 15/332 (4%)
Query: 40 LNLTDEALRLKYLGPQQTELFMPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYL 99
LN T+E L GP+++ F+P+ Y+ IFVVG +GN L CLVIL+H+AM+TPTNYYL
Sbjct: 26 LNSTEEYLAF-LCGPRRSHFFLPVSVVYVPIFVVGVIGNVLVCLVILQHQAMKTPTNYYL 84
Query: 100 FSLAVSDLLVLLVGLPLELYEMWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVER 159
FSLAVSDLLVLL+G+PLE+YEMW NYPFL G GCYF+T LFE VC AS+L++T +SVER
Sbjct: 85 FSLAVSDLLVLLLGMPLEVYEMWRNYPFLFGPVGCYFKTALFETVCFASILSITTVSVER 144
Query: 160 YVAVVHPLQARSMVTRAHVRRVLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVC 219
YVA++HP +A+ TR R+LG VWG ++L SLPNTS+HGI+ + P VP SA C
Sbjct: 145 YVAILHPFRAKLQSTRRRALRILGIVWGFSVLFSLPNTSIHGIKFHYFPNGSLVPGSATC 204
Query: 220 MLVRPRALYNMVVQTTALLFFCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARS 279
+++P +YN ++Q T+ LF+ LPM ++SVLY L+ LRL++++ L E A
Sbjct: 205 TVIKPMWIYNFIIQVTSFLFYLLPMTVISVLYYLMALRLKKDKSLEADEGN------ANI 258
Query: 280 RYTCRLQQHDRGRRQVTKMLFVLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHV 339
+ C R+ V KMLFVLV+VF ICWAPFH DR+ +S V +W++ L F VHV
Sbjct: 259 QRPC--------RKSVNKMLFVLVLVFAICWAPFHIDRLFFSFVEEWSESLAAVFNLVHV 310
Query: 340 ISGIFFYLGSAANPVLYSLMSSRFRETFQEAL 371
+SG+FFYL SA NP++Y+L+S RF+ FQ +
Sbjct: 311 VSGVFFYLSSAVNPIIYNLLSRRFQAAFQNVI 342
>gi|110611243 neurotensin receptor 1 [Homo sapiens]
Length = 418
Score = 179 bits (455), Expect = 3e-45
Identities = 111/358 (31%), Positives = 192/358 (53%), Gaps = 28/358 (7%)
Query: 63 ICATYLLIFVVGAVGNGLTCLVILRHKAMRT---PTNYYLFSLAVSDLLVLLVGLPLELY 119
+ A YL +FVVG VGN +T + R K++++ +Y+L SLA+SDLL LL+ +P+ELY
Sbjct: 66 VTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELY 125
Query: 120 E-MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHV 178
+W ++P+ G GC L + A+ LNV +LSVERY+A+ HP +A+++++R+
Sbjct: 126 NFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRT 185
Query: 179 RRVLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALL 238
++ + A+W + L ++P L + + + G VC A +V+Q +
Sbjct: 186 KKFISAIWLASALLAVP--MLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFM 243
Query: 239 FFCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAA----RSRYTCRLQQ-HDRGRR 293
F PM ++SVL +I +L +++++A +G S ++ ++ + R
Sbjct: 244 SFIFPMVVISVLNTIIANKL----TVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALR 299
Query: 294 QVTKMLFVLVVVFGICWAPFHADRVMWSVVS--QWTDGLHLAFQHVHVISGIFFYLGSAA 351
++L +V+ F +CW P+H R+M+ +S QWT L+ + + ++++ FY+ S
Sbjct: 300 HGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTI 359
Query: 352 NPVLYSLMSSRFRETFQEAL-CLGACCHRLRPR----------HSSHSLSRMTTGSTL 398
NP+LY+L+S+ FR F L CL R R R S+H+LS T TL
Sbjct: 360 NPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETL 417
>gi|4504095 motilin receptor [Homo sapiens]
Length = 412
Score = 174 bits (442), Expect = 1e-43
Identities = 129/383 (33%), Positives = 192/383 (50%), Gaps = 67/383 (17%)
Query: 61 MPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE 120
+P+ A L +FVVG GN +T ++I R++ MRT TN YL S+AVSDLL+LL GLP +LY
Sbjct: 39 VPVTAVCLCLFVVGVSGNVVTVMLIGRYRDMRTTTNLYLGSMAVSDLLILL-GLPFDLYR 97
Query: 121 MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRR 180
+W + P++ G C + E A++L++TALSVERY+A+ PL+AR +VTR VR
Sbjct: 98 LWRSRPWVFGPLLCRLSLYVGEGCTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRA 157
Query: 181 VLGAVWGLAMLCSLPNTSLHGIRQ---LHV------------------------------ 207
++ +W +A+L + P L G+ Q + V
Sbjct: 158 LIAVLWAVALLSAGPFLFLVGVEQDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPPS 217
Query: 208 PCRGPVPDSAVCMLVRP--------RALYNMVVQTTALLFFCLPMAIMSVLYLLIGLRLR 259
P GP A + R AL M+ TTA +F LP +S+LY LIG L
Sbjct: 218 PPSGPETAEAAALFSRECRPSPAQLGALRVMLWVTTA--YFFLPFLCLSILYGLIGRELW 275
Query: 260 RERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLFVLVVVFGICWAPFHADRVM 319
R L RG AA+ +RG RQ ++L V+V+ F ICW PFH R++
Sbjct: 276 SSRRPL------RGPAASG---------RERGHRQTVRVLLVVVLAFIICWLPFHVGRII 320
Query: 320 WSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMSSRFRETFQEALCLGACCHR 379
+ ++ + Q+ ++++ FYL ++ NP+LY+L+S ++R + L +
Sbjct: 321 Y--INTEDSRMMYFSQYFNIVALQLFYLSASINPILYNLISKKYRAAAFKLL----LARK 374
Query: 380 LRPRHSSHSLSRMTTGSTLCDVG 402
RPR SR T G D G
Sbjct: 375 SRPR--GFHRSRDTAGEVAGDTG 395
>gi|38455410 growth hormone secretagogue receptor isoform 1a [Homo
sapiens]
Length = 366
Score = 167 bits (423), Expect = 2e-41
Identities = 122/335 (36%), Positives = 179/335 (53%), Gaps = 35/335 (10%)
Query: 37 PEDLNLTDEALRLKYLGPQQTELFMPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTN 96
P + +L DE L+L + P L + AT + +FVVG GN LT LV+ R + +RT TN
Sbjct: 25 PGNDSLGDELLQL-FPAP----LLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTN 79
Query: 97 YYLFSLAVSDLLVLLVGLPLELYEMWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALS 156
YL S+A SDLL+ L +PL+L +W P+ G C + E A+VL +TALS
Sbjct: 80 LYLSSMAFSDLLIFLC-MPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALS 138
Query: 157 VERYVAVVHPLQARSMVTRAHVRRVLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVP-D 215
VERY A+ PL+A+ +VT+ V+ V+ +W +A + P L G+ + G P D
Sbjct: 139 VERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHEN----GTDPWD 194
Query: 216 SAVC----MLVRPRALYNMVVQTTALLFFCLPMAIMSVLYLLIGLRLRRERLLLMQEAKG 271
+ C VR L MV + +FF LP+ ++VLY LIG +L R R
Sbjct: 195 TNECRPTEFAVRSGLLTVMV--WVSSIFFFLPVFCLTVLYSLIGRKLWRRR--------- 243
Query: 272 RGSAAARSRYTCRLQQHDRGRRQVTKMLFVLVVVFGICWAPFHADRVMWSVVSQWTDGLH 331
RG A + D+ +Q KML V+V F +CW PFH R ++S S L
Sbjct: 244 RGDAVVGA------SLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFS-KSFEPGSLE 296
Query: 332 LA--FQHVHVISGIFFYLGSAANPVLYSLMSSRFR 364
+A Q+ +++S + FYL +A NP+LY++MS ++R
Sbjct: 297 IAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYR 331
>gi|6912538 neurotensin receptor 2 [Homo sapiens]
Length = 410
Score = 160 bits (404), Expect = 3e-39
Identities = 115/369 (31%), Positives = 190/369 (51%), Gaps = 42/369 (11%)
Query: 65 ATYLLIFVVGAVGNGLTCLVILRHKAMRTPT-NYYLFSLAVSDLLVLLVGLPLELYE-MW 122
A Y LI+ +GA GN L+ V+L+ +A R +++ SLA++ LL+LLVG+P+ELY +W
Sbjct: 37 ALYALIWALGAAGNALSVHVVLKARAGRAGRLRHHVLSLALAGLLLLLVGVPVELYSFVW 96
Query: 123 HNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVL 182
+YP++ G GC + E+ A+VL+V LS ER +AV PL+ARS++T R ++
Sbjct: 97 FHYPWVFGDLGCRGYYFVHELCAYATVLSVAGLSAERCLAVCQPLRARSLLTPRRTRWLV 156
Query: 183 GAVWGLAMLCSLPNTSLHGIR-QLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFFC 241
W ++ +LP + G + +L P P S VC ++ R + +Q L+ F
Sbjct: 157 ALSWAASLGLALPMAVIMGQKHELETADGEPEPASRVCTVLVSRTALQVFIQVNVLVSFV 216
Query: 242 LPMAI------MSVLYLLI-----------GLRLRRERLLLMQEA------------KGR 272
LP+A+ ++V +LL G LL +E +G
Sbjct: 217 LPLALTAFLNGVTVSHLLALCSQVPSTSTPGSSTPSRLELLSEEGLLSFIVWKKTFIQGG 276
Query: 273 GSAAARSRYTCRLQQHDRGRRQVTKMLFVLVVVFGICWAPFHADRVMWSVV--SQWTDGL 330
+ R + R+ R ++ ++L +VV++ ICW P+HA R+M+ V WTD L
Sbjct: 277 QVSLVRHKDVRRI----RSLQRSVQVLRAIVVMYVICWLPYHARRLMYCYVPDDAWTDPL 332
Query: 331 HLAFQHVHVISGIFFYLGSAANPVLYSLMSSRFRETFQEALCLGACCH----RLRPRHSS 386
+ + + ++++ FY+ SA P+LY+ +SS FR+ F EA+ H RL P+ S
Sbjct: 333 YNFYHYFYMVTNTLFYVSSAVTPLLYNAVSSSFRKLFLEAVSSLCGEHHPMKRLPPKPQS 392
Query: 387 HSLSRMTTG 395
+L +G
Sbjct: 393 PTLMDTASG 401
>gi|149944554 somatostatin receptor 4 [Homo sapiens]
Length = 388
Score = 140 bits (352), Expect = 3e-33
Identities = 118/368 (32%), Positives = 173/368 (47%), Gaps = 43/368 (11%)
Query: 12 PGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELFMPICATYLLIF 71
P L PGG SAA P + +EA+ G + + I Y L+
Sbjct: 4 PSTLPPGGEEGLGTAWPSAANASSAPAE---AEEAVAGP--GDARAAGMVAIQCIYALVC 58
Query: 72 VVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWHNYPFLLGV 131
+VG VGN L VILR+ M+T TN YL +LAV+D L +L + ++PF
Sbjct: 59 LVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPF---- 114
Query: 132 GGCYFRTLLF--EMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAVWGLA 189
G R +L + SV +T LSV+RYVAVVHPL+A + + + + VW +
Sbjct: 115 GSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLAS 174
Query: 190 MLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMV-VQTTALLFFCLPMAIMS 248
+L +LP R P RG + C L P ++ V V T LL F LP+ +
Sbjct: 175 LLVTLPIAIFADTR----PARG--GQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIG 228
Query: 249 VLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLFVLVVVFGI 308
+ YLLI ++R + A R+ + QQ R +++T+++ ++VVVF +
Sbjct: 229 LCYLLIVGKMR--------------AVALRAGW----QQRRRSEKKITRLVLMVVVVFVL 270
Query: 309 CWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMSSRFRETFQ 368
CW PF+ +++ + + L HV S I Y S ANP+LY +S FR FQ
Sbjct: 271 CWMPFYVVQLL----NLFVTSLDATVNHV---SLILSYANSCANPILYGFLSDNFRRFFQ 323
Query: 369 EALCLGAC 376
LCL C
Sbjct: 324 RVLCLRCC 331
>gi|63477962 opioid receptor, delta 1 [Homo sapiens]
Length = 372
Score = 130 bits (328), Expect = 2e-30
Identities = 118/380 (31%), Positives = 177/380 (46%), Gaps = 59/380 (15%)
Query: 23 PMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELFMPICATYLLIFVVGAVGNGLTC 82
P AC + A P + + AL + T L+ +CA VG +GN L
Sbjct: 24 PSACPSAGANASGPPGARSASSLALAIAI-----TALYSAVCA-------VGLLGNVLVM 71
Query: 83 LVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLE----LYEMWHNYPFLLGVGGCYFRT 138
I+R+ M+T TN Y+F+LA++D L LP + L E W PF G C
Sbjct: 72 FGIVRYTKMKTATNIYIFNLALADALATST-LPFQSAKYLMETW---PF--GELLCKAVL 125
Query: 139 LLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAVWGLAMLCSLPNTS 198
+ S+ +T +SV+RY+AV HP++A T A + + +W LA +P
Sbjct: 126 SIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMV 185
Query: 199 LHGIRQLHVPCRGPVPDSAVCML--VRPRALYNMVVQTTALLF-FCLPMAIMSVLYLLIG 255
+ R P + VCML P ++ V + LF F +P+ I++V Y L+
Sbjct: 186 MAVTR--------PRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLML 237
Query: 256 LRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLFVLVVVFGICWAPFHA 315
LRLR RLL GS ++ DR R++T+M+ V+V F +CWAP H
Sbjct: 238 LRLRSVRLL-------SGS-----------KEKDRSLRRITRMVLVVVGAFVVCWAPIHI 279
Query: 316 DRVMWSVVS-QWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMSSRFRETFQEALCLG 374
++W++V D L +A H+ + G Y S+ NPVLY+ + F+ F++ LC
Sbjct: 280 FVIVWTLVDIDRRDPLVVAALHLCIALG---YANSSLNPVLYAFLDENFKRCFRQ-LCRK 335
Query: 375 ACCHRLRPRHSSHSLSRMTT 394
C RP SS S +R T
Sbjct: 336 PCG---RPDPSSFSRAREAT 352
>gi|4507681 thyrotropin-releasing hormone receptor [Homo sapiens]
Length = 398
Score = 125 bits (315), Expect = 6e-29
Identities = 109/358 (30%), Positives = 173/358 (48%), Gaps = 51/358 (14%)
Query: 41 NLTDEALRLKYLGPQQTELFMPICATYLLIFVV---GAVGNGLTCLVILRHKAMRTPTNY 97
N T L L P+ T LL+ ++ G VGN + LV++R K MRTPTN
Sbjct: 3 NETVSELNQTQLQPRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNC 62
Query: 98 YLFSLAVSDLLVLL-VGLPL---ELYEMWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVT 153
YL SLAV+DL+VL+ GLP +Y W + G GC T L + AS ++T
Sbjct: 63 YLVSLAVADLMVLVAAGLPNITDSIYGSW-----VYGYVGCLCITYLQYLGINASSCSIT 117
Query: 154 ALSVERYVAVVHPLQARSMVTRAHVRRVLGAVWGLAML-CSLPNTSLHGIRQLHVPCRGP 212
A ++ERY+A+ HP++A+ + T + ++++ VW L C L + L++
Sbjct: 118 AFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCML----WFFLLDLNI---ST 170
Query: 213 VPDSAV--CMLVRPRALYNMVVQTTALLFFCLPMAIMSVLYLLIGLRLRRERLLLM---- 266
D+ V C R Y+ + +F+ +PM + +VLY I R+L +
Sbjct: 171 YKDAIVISCGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIA------RILFLNPIP 224
Query: 267 ----QEAKGRGSAAARSRYTCRLQQHDR-------GRRQVTKMLFVLVVVFGICWAPFHA 315
+ +K + + + +R R+QVTKML V+V++F + W P+
Sbjct: 225 SDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRT 284
Query: 316 DRVMWSVVSQ-WTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMSSRFRETFQEALC 372
V+ S +S + + L F + + YL SA NPV+Y+LMS +FR F++ LC
Sbjct: 285 LVVVNSFLSSPFQENWFLLFCRICI------YLNSAINPVIYNLMSQKFRAAFRK-LC 335
>gi|157738685 G protein-coupled receptor 103 [Homo sapiens]
Length = 431
Score = 124 bits (312), Expect = 1e-28
Identities = 87/336 (25%), Positives = 159/336 (47%), Gaps = 15/336 (4%)
Query: 61 MPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE 120
+ + T +LIF + GN L V+ R KAMRT TN ++ SLA+SDLL+ +P+ + +
Sbjct: 46 LALVLTGVLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQ 105
Query: 121 MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRR 180
+ +L G C + + +L +T ++VER+ +VHP + + T
Sbjct: 106 NISD-NWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFT 164
Query: 181 VLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALL-- 238
+LG VW +A++ P + ++QL + +C L + + + TT +L
Sbjct: 165 MLGVVWLVAVIVGSP---MWHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILVI 221
Query: 239 FFCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKM 298
F LP+ +M +LY IG L +++ G GS R+ + + + R +++ M
Sbjct: 222 LFLLPLMVMLILYSKIGYE------LWIKKRVGDGS-VLRTIHGKEMSKIARKKKRAVIM 274
Query: 299 LFVLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSL 358
+ +V +F +CWAPFH +M + + + + + I I + S NP++Y+
Sbjct: 275 MVTVVALFAVCWAPFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAF 334
Query: 359 MSSRFRETFQEALCLGACCHRLRP--RHSSHSLSRM 392
M+ F++ A+C P RH + ++ M
Sbjct: 335 MNENFKKNVLSAVCYCIVNKTFSPAQRHGNSGITMM 370
>gi|4557865 somatostatin receptor 5 [Homo sapiens]
Length = 364
Score = 123 bits (309), Expect = 3e-28
Identities = 101/315 (32%), Positives = 148/315 (46%), Gaps = 48/315 (15%)
Query: 67 YLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLP-LELYEMWHNY 125
YLL+ G GN L V+LR M+T TN Y+ +LAV+D+L +L GLP L +
Sbjct: 47 YLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYML-GLPFLATQNAASFW 105
Query: 126 PFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAV 185
PF G C L + SV +T +SV+RY+AVVHPL + + A
Sbjct: 106 PF--GPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAA 163
Query: 186 WGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMV-VQTTALLFFCLPM 244
W L++ SLP +++ C P+ P L+ V + TA+L F P+
Sbjct: 164 WVLSLCMSLPLLVFADVQE-GGTCNASWPE--------PVGLWGAVFIIYTAVLGFFAPL 214
Query: 245 AIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLFVLVV 304
++ + YLLI +++R AA R C R R+VT+M+ V+V+
Sbjct: 215 LVICLCYLLIVVKVR----------------AAGVRVGC---VRRRSERKVTRMVLVVVL 255
Query: 305 VFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFF------YLGSAANPVLYSL 358
VF CW PF ++ L +A +G++F Y S ANPVLY
Sbjct: 256 VFAGCWLPFFTVNIV---------NLAVALPQEPASAGLYFFVVILSYANSCANPVLYGF 306
Query: 359 MSSRFRETFQEALCL 373
+S FR++FQ+ LCL
Sbjct: 307 LSDNFRQSFQKVLCL 321
>gi|7669548 tachykinin receptor 3 [Homo sapiens]
Length = 465
Score = 123 bits (309), Expect = 3e-28
Identities = 83/314 (26%), Positives = 148/314 (47%), Gaps = 45/314 (14%)
Query: 67 YLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLV----LLVGLPLELYEMW 122
Y ++ V +GN + +IL HK MRT TNY+L +LA SD + LV L+ W
Sbjct: 92 YGVVVAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALHSEW 151
Query: 123 HNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVL 182
+ G C F+ AS+ ++TA++V+RY+A++ PL+ R T + V+
Sbjct: 152 Y-----FGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKI--VI 204
Query: 183 GAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRA-----LYNMVVQTTAL 237
G++W LA L + P + + P +C + P Y+++V +
Sbjct: 205 GSIWILAFLLAFPQCLYSKTKVM--------PGRTLCFVQWPEGPKQHFTYHIIV---II 253
Query: 238 LFFCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTC-RLQQHDRGRRQVT 296
L +C P+ IM + Y ++G+ L + TC + + + +R+V
Sbjct: 254 LVYCFPLLIMGITYTIVGITLWGGEI---------------PGDTCDKYHEQLKAKRKVV 298
Query: 297 KMLFVLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLY 356
KM+ ++V+ F ICW P+H ++ ++ Q ++ Q V++ S + NP++Y
Sbjct: 299 KMMIIVVMTFAICWLPYHIYFILTAIYQQLNRWKYI--QQVYLASFWLAMSSTMYNPIIY 356
Query: 357 SLMSSRFRETFQEA 370
++ RFR F+ A
Sbjct: 357 CCLNKRFRAGFKRA 370
>gi|4557861 somatostatin receptor 3 [Homo sapiens]
Length = 418
Score = 122 bits (306), Expect = 6e-28
Identities = 93/306 (30%), Positives = 149/306 (48%), Gaps = 29/306 (9%)
Query: 67 YLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLP-LELYEMWHNY 125
YL++ VVG +GN L V+LRH A + TN Y+ +LA++D L +L GLP L +
Sbjct: 51 YLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFML-GLPFLAAQNALSYW 109
Query: 126 PFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAV 185
PF G C + + S+ +T +SV+RY+AVVHP ++ T R V AV
Sbjct: 110 PF--GSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAV 167
Query: 186 WGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFFCLPMA 245
W + + LP G+ + C P+ A ++ T AL FF P+
Sbjct: 168 WVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRA------GFIIYTAALGFFG-PLL 220
Query: 246 IMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLFVLVVV 305
++ + YLLI +++R +A R + Q+ R R+VT+M+ +V +
Sbjct: 221 VICLCYLLIVVKVR---------------SAGRRVWAPSCQRRRRSERRVTRMVVAVVAL 265
Query: 306 FGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMSSRFRE 365
F +CW PF+ ++ +VV + AF ++ + Y S ANP+LY +S RF++
Sbjct: 266 FVLCWMPFYVLNIV-NVVCPLPE--EPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQ 322
Query: 366 TFQEAL 371
F+ L
Sbjct: 323 GFRRVL 328
>gi|4557857 somatostatin receptor 1 [Homo sapiens]
Length = 391
Score = 122 bits (305), Expect = 8e-28
Identities = 98/313 (31%), Positives = 154/313 (49%), Gaps = 43/313 (13%)
Query: 67 YLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWHNYP 126
Y ++ +VG GN + VILR+ M+T TN Y+ +LA++D L++L L + ++P
Sbjct: 65 YSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWP 124
Query: 127 FLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLG-AV 185
F G C + + S+ +T LSV+RYVAVVHP++A + R V +V+ V
Sbjct: 125 F--GALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKA-ARYRRPTVAKVVNLGV 181
Query: 186 WGLAMLCSLP-----NTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFF 240
W L++L LP T+ + V C +P+ A LV V T L+ F
Sbjct: 182 WVLSLLVILPIVVFSRTAANS--DGTVACNMLMPEPAQRWLVG-------FVLYTFLMGF 232
Query: 241 CLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLF 300
LP+ + + Y+LI ++R L QQ R R++T M+
Sbjct: 233 LLPVGAICLCYVLIIAKMRMVAL------------------KAGWQQRKRSERKITLMVM 274
Query: 301 VLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMS 360
++V+VF ICW PF+ +++ +V ++ D V +S I Y S ANP+LY +S
Sbjct: 275 MVVMVFVICWMPFYVVQLV-NVFAEQDDAT------VSQLSVILGYANSCANPILYGFLS 327
Query: 361 SRFRETFQEALCL 373
F+ +FQ LCL
Sbjct: 328 DNFKRSFQRILCL 340
>gi|4505513 opiate receptor-like 1 [Homo sapiens]
Length = 370
Score = 122 bits (305), Expect = 8e-28
Identities = 100/325 (30%), Positives = 153/325 (47%), Gaps = 44/325 (13%)
Query: 59 LFMPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLE- 117
L + I YL + V G +GN L VILRH M+T TN Y+F+LA++D LVLL LP +
Sbjct: 50 LKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLT-LPFQG 108
Query: 118 ---LYEMWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVT 174
L W PF G C + S +TA+SV+RYVA+ HP++A + T
Sbjct: 109 TDILLGFW---PF--GNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRT 163
Query: 175 RAHVRRVLGAVWGLAMLCSLPNTSLHGIRQL---HVPCRGPVPDSAVCMLVRPRALYNMV 231
+ + V A+W LA + +P ++ G Q+ + C +P P+ + V
Sbjct: 164 SSKAQAVNVAIWALASVVGVP-VAIMGSAQVEDEEIECLVEIP--------TPQDYWGPV 214
Query: 232 VQTTALLF-FCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDR 290
LF F +P+ ++SV Y L+ RLR RLL GS ++ DR
Sbjct: 215 FAICIFLFSFIVPVLVISVCYSLMIRRLRGVRLL-------SGS-----------REKDR 256
Query: 291 GRRQVTKMLFVLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSA 350
R++T+++ V+V VF CW P + + Q + +A G Y+ S
Sbjct: 257 NLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAILRFCTALG---YVNSC 313
Query: 351 ANPVLYSLMSSRFRETFQEALCLGA 375
NP+LY+ + F+ F++ C A
Sbjct: 314 LNPILYAFLDENFKACFRKFCCASA 338
>gi|33286424 opiate receptor-like 1 [Homo sapiens]
Length = 370
Score = 122 bits (305), Expect = 8e-28
Identities = 100/325 (30%), Positives = 153/325 (47%), Gaps = 44/325 (13%)
Query: 59 LFMPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLE- 117
L + I YL + V G +GN L VILRH M+T TN Y+F+LA++D LVLL LP +
Sbjct: 50 LKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLT-LPFQG 108
Query: 118 ---LYEMWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVT 174
L W PF G C + S +TA+SV+RYVA+ HP++A + T
Sbjct: 109 TDILLGFW---PF--GNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRT 163
Query: 175 RAHVRRVLGAVWGLAMLCSLPNTSLHGIRQL---HVPCRGPVPDSAVCMLVRPRALYNMV 231
+ + V A+W LA + +P ++ G Q+ + C +P P+ + V
Sbjct: 164 SSKAQAVNVAIWALASVVGVP-VAIMGSAQVEDEEIECLVEIP--------TPQDYWGPV 214
Query: 232 VQTTALLF-FCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDR 290
LF F +P+ ++SV Y L+ RLR RLL GS ++ DR
Sbjct: 215 FAICIFLFSFIVPVLVISVCYSLMIRRLRGVRLL-------SGS-----------REKDR 256
Query: 291 GRRQVTKMLFVLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSA 350
R++T+++ V+V VF CW P + + Q + +A G Y+ S
Sbjct: 257 NLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAILRFCTALG---YVNSC 313
Query: 351 ANPVLYSLMSSRFRETFQEALCLGA 375
NP+LY+ + F+ F++ C A
Sbjct: 314 LNPILYAFLDENFKACFRKFCCASA 338
>gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens]
Length = 407
Score = 121 bits (304), Expect = 1e-27
Identities = 107/379 (28%), Positives = 170/379 (44%), Gaps = 64/379 (16%)
Query: 65 ATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWHN 124
A Y +I V VGN + +IL HK MRT TNY+L +LA ++ + + HN
Sbjct: 37 AAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHN 96
Query: 125 YPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGA 184
+ G+ C F AS+ ++TA++ +RY+A++HPLQ R T V V+
Sbjct: 97 -EWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKV--VICV 153
Query: 185 VWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCML---VRPRALYNMV--VQTTALLF 239
+W LA+L + P Q + +P VCM+ P +Y V + T L++
Sbjct: 154 IWVLALLLAFP--------QGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIY 205
Query: 240 FCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKML 299
F LP+ ++ Y ++G+ L E G S R + +R+V KM+
Sbjct: 206 F-LPLLVIGYAYTVVGI------TLWASEIPGDSSD--------RYHEQVSAKRKVVKMM 250
Query: 300 FVLVVVFGICWAPFHADRVMWSVVSQWTDGLHLA--FQHVHVISGIFFYLGSAANPVLYS 357
V+V F ICW PFH ++ ++ L+L Q V++ + NP++Y
Sbjct: 251 IVVVCTFAICWLPFH----IFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYC 306
Query: 358 LMSSRFRETFQEALCLGACC----------------HRLRPRHSSHSLSRM-TTGSTLCD 400
++ RFR F+ A CC L+ + S + +SR+ TT ST+
Sbjct: 307 CLNDRFRLGFKHAF---RCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRLETTISTV-- 361
Query: 401 VGSLGSWVHPLAGNDGPEA 419
VG+ H DGP+A
Sbjct: 362 VGA-----HEEEPEDGPKA 375
>gi|4557859 somatostatin receptor 2 [Homo sapiens]
Length = 369
Score = 121 bits (304), Expect = 1e-27
Identities = 91/312 (29%), Positives = 155/312 (49%), Gaps = 37/312 (11%)
Query: 67 YLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLP-LELYEMWHNY 125
Y ++ ++G GN L VILR+ M+T TN Y+ +LA++D L +L GLP L + ++
Sbjct: 50 YFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFML-GLPFLAMQVALVHW 108
Query: 126 PFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAV 185
PF G C + + S+ +T +S++RY+AVVHP+++ + + AV
Sbjct: 109 PF--GKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAV 166
Query: 186 WGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRP---RALYNMVVQTTALLFFCL 242
WG+++L LP G+R + C + P A Y + T +L F +
Sbjct: 167 WGVSLLVILPIMIYAGLRSNQW-------GRSSCTINWPGESGAWYTGFIIYTFILGFLV 219
Query: 243 PMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLFVL 302
P+ I+ + YL I ++++ + + GS+ + + ++VT+M+ ++
Sbjct: 220 PLTIICLCYLFIIIKVKSSGIRV-------GSS-----------KRKKSEKKVTRMVSIV 261
Query: 303 VVVFGICWAPFHADRV-MWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMSS 361
V VF CW PF+ V S+ T L F V V++ Y S ANP+LY+ +S
Sbjct: 262 VAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLT----YANSCANPILYAFLSD 317
Query: 362 RFRETFQEALCL 373
F+++FQ LCL
Sbjct: 318 NFKKSFQNVLCL 329
>gi|4758434 growth hormone secretagogue receptor isoform 1b [Homo
sapiens]
Length = 289
Score = 120 bits (301), Expect = 2e-27
Identities = 96/268 (35%), Positives = 137/268 (51%), Gaps = 32/268 (11%)
Query: 37 PEDLNLTDEALRLKYLGPQQTELFMPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTN 96
P + +L DE L+L + P L + AT + +FVVG GN LT LV+ R + +RT TN
Sbjct: 25 PGNDSLGDELLQL-FPAP----LLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTN 79
Query: 97 YYLFSLAVSDLLVLLVGLPLELYEMWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALS 156
YL S+A SDLL+ L +PL+L +W P+ G C + E A+VL +TALS
Sbjct: 80 LYLSSMAFSDLLIFLC-MPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALS 138
Query: 157 VERYVAVVHPLQARSMVTRAHVRRVLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVP-D 215
VERY A+ PL+A+ +VT+ V+ V+ +W +A + P L G+ + G P D
Sbjct: 139 VERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHEN----GTDPWD 194
Query: 216 SAVC----MLVRPRALYNMVVQTTALLFFCLPMAIMSVLYLLIGLRLRRERLLLMQEAKG 271
+ C VR L MV + +FF LP+ ++VLY LIG +L R R
Sbjct: 195 TNECRPTEFAVRSGLLTVMV--WVSSIFFFLPVFCLTVLYSLIGRKLWRRR--------- 243
Query: 272 RGSAAARSRYTCRLQQHDRGRRQVTKML 299
RG A + D+ +Q KML
Sbjct: 244 RGDAVVGA------SLRDQNHKQTVKML 265
>gi|157426873 tachykinin receptor 2 [Homo sapiens]
Length = 398
Score = 119 bits (299), Expect = 4e-27
Identities = 88/320 (27%), Positives = 154/320 (48%), Gaps = 33/320 (10%)
Query: 67 YLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWHNYP 126
YL + +V GN + +IL H+ MRT TNY++ +LA++DL + HN
Sbjct: 40 YLALVLVAVTGNAIVIWIILAHRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNI- 98
Query: 127 FLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAVW 186
+ G CYF+ L S+ ++TA++ +RY+A+VHP Q R ++ + V+ +W
Sbjct: 99 WYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPR--LSAPSTKAVIAGIW 156
Query: 187 GLAMLCSLPNT--SLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFFCLPM 244
+A+ + P S + Q C P+ + + LY++VV AL++F LP+
Sbjct: 157 LVALALASPQCFYSTVTMDQGATKCVVAWPEDSG---GKTLLLYHLVV--IALIYF-LPL 210
Query: 245 AIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLFVLVV 304
A+M V Y +IGL L R + G + A R H + ++ K + ++V+
Sbjct: 211 AVMFVAYSVIGLTLWR------RAVPGHQAHGANLR-------HLQAMKKFVKTMVLVVL 257
Query: 305 VFGICWAPFHADRVMWSVVSQWTDGL--HLAFQHVHVISGIFFYLGSAANPVLYSLMSSR 362
F ICW P+H ++ ++ + + + H Q V++ + NP++Y ++ R
Sbjct: 258 TFAICWLPYH----LYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHR 313
Query: 363 FRETFQEALCLGACCHRLRP 382
FR F+ A CC + P
Sbjct: 314 FRSGFRLAF---RCCPWVTP 330
>gi|39725940 opioid receptor, kappa 1 [Homo sapiens]
Length = 380
Score = 119 bits (298), Expect = 5e-27
Identities = 92/335 (27%), Positives = 157/335 (46%), Gaps = 41/335 (12%)
Query: 63 ICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMW 122
I A Y ++FVVG VGN L VI+R+ M+T TN Y+F+LA++D LV +
Sbjct: 62 ITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLM 121
Query: 123 HNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVL 182
+++PF G C + S+ +T +SV+RY+AV HP++A T + +
Sbjct: 122 NSWPF--GDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIIN 179
Query: 183 GAVWGLAMLCSLPNTSLHGIRQLH----VPCRGPVPDSAVCMLVRPRALYNMVVQTTALL 238
+W L+ + L G + + C PD + +++ ++ +
Sbjct: 180 ICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDD-------DYSWWDLFMKICVFI 232
Query: 239 F-FCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTK 297
F F +P+ I+ V Y L+ LRL+ RLL GS ++ DR R++T+
Sbjct: 233 FAFVIPVLIIIVCYTLMILRLKSVRLL-------SGS-----------REKDRNLRRITR 274
Query: 298 MLFVLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYS 357
++ V+V VF +CW P H ++ ++ S L+ + + G Y S+ NP+LY+
Sbjct: 275 LVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALG---YTNSSLNPILYA 331
Query: 358 LMSSRFRETFQEALCLGACCHRLRPRHSSHSLSRM 392
+ F+ F++ C L+ R S SR+
Sbjct: 332 FLDENFKRCFRD------FCFPLKMRMERQSTSRV 360
>gi|222080095 orexin receptor 1 [Homo sapiens]
Length = 425
Score = 118 bits (295), Expect = 1e-26
Identities = 109/434 (25%), Positives = 188/434 (43%), Gaps = 74/434 (17%)
Query: 17 PGGARNPMACNGSAARGHFDPEDLNLTDEALRL---KYLGPQQTELFMPICATYLLIFVV 73
P G+R P P + DE LR YL P+Q E + A Y+ +FVV
Sbjct: 14 PPGSREP------------SPVPPDYEDEFLRYLWRDYLYPKQYEWVL--IAAYVAVFVV 59
Query: 74 GAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLP----LELYEMWHNYPFLL 129
VGN L CL + R+ MRT TNY++ +L+++D+LV + LP +++ E W L
Sbjct: 60 ALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESW-----LF 114
Query: 130 GVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAVWGLA 189
G C L + +VL ++ ++++R+ A+ HPL +S RA R + +W ++
Sbjct: 115 GHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRA--RGSILGIWAVS 172
Query: 190 MLCSLPNTSLHGIRQLHVPCRGPVPDSA-------VCMLVRPRALYNMVVQTT-ALLFFC 241
+ +P ++ + C +P+ A VC LY + + ++ +
Sbjct: 173 LAIMVPQAAV-------MECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYL 225
Query: 242 LPMAIMSVLYLLIGLRLRRERLLLMQEAKGR-----------------GSAAARSRYTCR 284
P+ +M++ Y I +L ++ A R G R+R
Sbjct: 226 APLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLA 285
Query: 285 LQQHDRGRRQVTKMLFVLVVVFGICWAPFHADRVMWSVVSQW-----TDGLHLAFQHVHV 339
+ R RR+ KML V+++VF +C+ P V+ V + + ++ F H
Sbjct: 286 EVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHW 345
Query: 340 ISGIFFYLGSAANPVLYSLMSSRFRETFQEALC-----LGACCHRLRPRHSSHSLSRMTT 394
+ Y SAANP++Y+ +S +FRE F+ A LG C P S + + +
Sbjct: 346 L----VYANSAANPIIYNFLSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLS 401
Query: 395 GSTLCDVGSLGSWV 408
+ C + + V
Sbjct: 402 LQSRCSISKISEHV 415
>gi|4502455 bombesin-like receptor 3 [Homo sapiens]
Length = 399
Score = 116 bits (290), Expect = 4e-26
Identities = 96/356 (26%), Positives = 153/356 (42%), Gaps = 32/356 (8%)
Query: 58 ELFMPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLE 117
E I TY +I VG +GN + V + K+M+T N ++ SLA DLL+LL +P++
Sbjct: 45 EALCAIYITYAVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVD 104
Query: 118 ----LYEMWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMV 173
L E W L G GC + + SV +T LS +RY AVV PL+ +
Sbjct: 105 ATHYLAEGW-----LFGRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSN 159
Query: 174 TRAHVRRVLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQ 233
G VW ++M+ +LP + P + +S V + L +
Sbjct: 160 AILKTCVKAGCVWIVSMIFALPEAIFSNVYTFRDPNKNMTFESCTSYPVSKKLLQEIHSL 219
Query: 234 TTALLFFCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRR 293
L+F+ +P++I+SV Y LI L + L + E + S R+
Sbjct: 220 LCFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQIES------------RK 267
Query: 294 QVTKMLFVLVVVFGICWAPFHADRVMWSVVSQW---TDGLHLAFQHVHVISGIFFYLGSA 350
++ + + VLV +F +CW P H + S SQ +H F + S + + S
Sbjct: 268 RIARTVLVLVALFALCWLPNHLLYLYHSFTSQTYVDPSAMHFIFT---IFSRVLAFSNSC 324
Query: 351 ANPVLYSLMSSRFRETFQEALCLGACCHRLRPRH--SSHSLSRMTTGSTLCDVGSL 404
NP +S F++ F+ L CC RP + SL+ + T+ GS+
Sbjct: 325 VNPFALYWLSKSFQKHFKAQL---FCCKAERPEPPVADTSLTTLAVMGTVPGTGSI 377
>gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens]
Length = 381
Score = 114 bits (284), Expect = 2e-25
Identities = 102/384 (26%), Positives = 173/384 (45%), Gaps = 68/384 (17%)
Query: 39 DLNLTDEALRLKYLGPQQT--------------------ELFMPICATYLLIFVVGAVGN 78
D N T E ++++ GPQ T E+ + + Y I ++G +GN
Sbjct: 9 DENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGN 68
Query: 79 GLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLEL-YEM---WHNYPFLLGVGGC 134
L V+++ K+MRT TN+++ +LAV+DLLV + LP L Y + W P L C
Sbjct: 69 SLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVL-----C 123
Query: 135 YFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAVWGLAMLCSL 194
+ + S + +T ++++R+ +V+ L+ S +++ ++G WG++ L +
Sbjct: 124 HLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLE--SKISKRISFLIIGLAWGISALLAS 181
Query: 195 PNTSLHGIRQLHVPCRGPVPDSAVCMLV-----RPRALYNMVVQTTALL-FFCLPMAIMS 248
P + + +PD + +++Y V ++LL + LP+ I+S
Sbjct: 182 PLAIFREYSLIEI-----IPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIIS 236
Query: 249 VLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLFVLVVVFGI 308
Y I +L+ AA Y H R R++ TKML +VVVF +
Sbjct: 237 FSYTRIWSKLKNH----------VSPGAANDHY------HQR-RQKTTKMLVCVVVVFAV 279
Query: 309 CWAPFHADRVMWSVVSQWTD--GLHLAFQHVHVISGIFFYLGSAANPVLYSLMSSRFRET 366
W P HA ++ + SQ D L F H+I+ + ANP+LY M+S +R+
Sbjct: 280 SWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIA----MCSTFANPLLYGWMNSNYRKA 335
Query: 367 FQEALCLGACCHRLRPRHSSHSLS 390
F A C RL HS S++
Sbjct: 336 FLSAF---RCEQRLDAIHSEVSVT 356
>gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens]
Length = 311
Score = 113 bits (283), Expect = 3e-25
Identities = 86/305 (28%), Positives = 140/305 (45%), Gaps = 37/305 (12%)
Query: 65 ATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWHN 124
A Y +I V VGN + +IL HK MRT TNY+L +LA ++ + + HN
Sbjct: 37 AAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHN 96
Query: 125 YPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGA 184
+ G+ C F AS+ ++TA++ +RY+A++HPLQ R T V V+
Sbjct: 97 -EWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKV--VICV 153
Query: 185 VWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCML---VRPRALYNMV--VQTTALLF 239
+W LA+L + P Q + +P VCM+ P +Y V + T L++
Sbjct: 154 IWVLALLLAFP--------QGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIY 205
Query: 240 FCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKML 299
F LP+ ++ Y ++G+ L E G S R + +R+V KM+
Sbjct: 206 F-LPLLVIGYAYTVVGI------TLWASEIPGDSSD--------RYHEQVSAKRKVVKMM 250
Query: 300 FVLVVVFGICWAPFHADRVMWSVVSQWTDGLHLA--FQHVHVISGIFFYLGSAANPVLYS 357
V+V F ICW PFH ++ ++ L+L Q V++ + NP++Y
Sbjct: 251 IVVVCTFAICWLPFH----IFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYC 306
Query: 358 LMSSR 362
++ R
Sbjct: 307 CLNDR 311
>gi|222080109 orexin receptor 2 [Homo sapiens]
Length = 444
Score = 110 bits (275), Expect = 2e-24
Identities = 99/379 (26%), Positives = 176/379 (46%), Gaps = 49/379 (12%)
Query: 50 KYLGPQQTELFMPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLV 109
+YL P++ E + A Y+++FVV +GN L C+ + ++ MRT TNY++ +L+++D+LV
Sbjct: 46 EYLHPKEYEWVL--IAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLV 103
Query: 110 LLVGLP----LELYEMWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVH 165
+ LP +++ E W G C L + SVL ++ ++++R+ A+ H
Sbjct: 104 TITCLPATLVVDITETW-----FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICH 158
Query: 166 PLQARSMVTRAHVRRVLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPR 225
PL +S RA R + +W ++ + +P + + VC
Sbjct: 159 PLMFKSTAKRA--RNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGG 216
Query: 226 ALY-NMVVQTTALLFFCLPMAIMSVLYLLIGLRL------------RRERLLLMQEAKGR 272
+Y M L+ + P+ +M + YL I +L +R+ L ++ R
Sbjct: 217 EIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPR 276
Query: 273 G----SAAARSRYTCRLQQHDRGRRQVTKMLFVLVVVFGICWAPFHADRVMWSVVSQWT- 327
G + + S ++Q R RR+ +ML ++++VF IC+ P V+ V +
Sbjct: 277 GPGQPTKSRMSAVAAEIKQ-IRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAH 335
Query: 328 ----DGLHLAFQHVHVISGIFFYLGSAANPVLYSLMSSRFRETFQEAL---CLGACCHR- 379
+ ++ F H + Y SAANP++Y+ +S +FRE F+ A CLG HR
Sbjct: 336 TEDRETVYAWFTFSHWL----VYANSAANPIIYNFLSGKFREEFKAAFSCCCLGV-HHRQ 390
Query: 380 ----LRPRHSSHSLSRMTT 394
R R S+ S +TT
Sbjct: 391 EDRLTRGRTSTESRKSLTT 409
>gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]
Length = 392
Score = 110 bits (274), Expect = 3e-24
Identities = 112/418 (26%), Positives = 181/418 (43%), Gaps = 66/418 (15%)
Query: 7 NCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELFMP---I 63
+CS P PG N +G+ + DP N TD R P + + I
Sbjct: 21 SCSPAPS---PGSWVNLSHLDGNLS----DPCGPNRTDLGGRDSLCPPTGSPSMITAITI 73
Query: 64 CATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWH 123
A Y ++ VVG GN L VI+R+ M+T TN Y+F+LA++D L LP +
Sbjct: 74 MALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST-LPFQ------ 126
Query: 124 NYPFLLGVGGCYFRTLLFEMV-------CLASVLNVTALSVERYVAVVHPLQARSMVTRA 176
+ +L+G F T+L ++V S+ + +SV+RY+AV HP++A T
Sbjct: 127 SVNYLMGTWP--FGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 184
Query: 177 HVRRVLGAVWGLAMLCSLP--NTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQT 234
+ + + W L+ LP + RQ + C P + +++
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDC--------TLTFSHPTWYWENLLKI 236
Query: 235 TALLF-FCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRR 293
+F F +P+ I++V Y L+ LRL+ R+L GS ++ DR R
Sbjct: 237 CVFIFAFIMPVLIITVCYGLMILRLKSVRML-------SGS-----------KEKDRNLR 278
Query: 294 QVTKMLFVLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANP 353
++T+M+ V+V VF +CW P H ++ ++V+ H + G Y S NP
Sbjct: 279 RITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALG---YTNSCLNP 335
Query: 354 VLYSLMSSRFRETFQEALCLGACCH-------RLRPRHSSHSLSRMTTGSTLCDVGSL 404
VLY+ + F+ F+E C+ + R+R H + T T V SL
Sbjct: 336 VLYAFLDENFKRCFRE-FCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQVRSL 392
>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
Length = 493
Score = 109 bits (273), Expect = 4e-24
Identities = 103/376 (27%), Positives = 168/376 (44%), Gaps = 58/376 (15%)
Query: 7 NCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELFMP---I 63
+CS P PG N +G+ + DP N TD R P + + I
Sbjct: 114 SCSPAPS---PGSWVNLSHLDGNLS----DPCGPNRTDLGGRDSLCPPTGSPSMITAITI 166
Query: 64 CATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWH 123
A Y ++ VVG GN L VI+R+ M+T TN Y+F+LA++D L LP +
Sbjct: 167 MALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST-LPFQ------ 219
Query: 124 NYPFLLGVGGCYFRTLLFEMV-------CLASVLNVTALSVERYVAVVHPLQARSMVTRA 176
+ +L+G F T+L ++V S+ + +SV+RY+AV HP++A T
Sbjct: 220 SVNYLMGTWP--FGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 277
Query: 177 HVRRVLGAVWGLAMLCSLP--NTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQT 234
+ + + W L+ LP + RQ + C P + +++
Sbjct: 278 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDC--------TLTFSHPTWYWENLLKI 329
Query: 235 TALLF-FCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRR 293
+F F +P+ I++V Y L+ LRL+ R+L GS ++ DR R
Sbjct: 330 CVFIFAFIMPVLIITVCYGLMILRLKSVRML-------SGS-----------KEKDRNLR 371
Query: 294 QVTKMLFVLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANP 353
++T+M+ V+V VF +CW P H ++ ++V+ H + G Y S NP
Sbjct: 372 RITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALG---YTNSCLNP 428
Query: 354 VLYSLMSSRFRETFQE 369
VLY+ + F+ F+E
Sbjct: 429 VLYAFLDENFKRCFRE 444
>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
Length = 400
Score = 109 bits (273), Expect = 4e-24
Identities = 103/376 (27%), Positives = 168/376 (44%), Gaps = 58/376 (15%)
Query: 7 NCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELFMP---I 63
+CS P PG N +G+ + DP N TD R P + + I
Sbjct: 21 SCSPAPS---PGSWVNLSHLDGNLS----DPCGPNRTDLGGRDSLCPPTGSPSMITAITI 73
Query: 64 CATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWH 123
A Y ++ VVG GN L VI+R+ M+T TN Y+F+LA++D L LP +
Sbjct: 74 MALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST-LPFQ------ 126
Query: 124 NYPFLLGVGGCYFRTLLFEMV-------CLASVLNVTALSVERYVAVVHPLQARSMVTRA 176
+ +L+G F T+L ++V S+ + +SV+RY+AV HP++A T
Sbjct: 127 SVNYLMGTWP--FGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 184
Query: 177 HVRRVLGAVWGLAMLCSLP--NTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQT 234
+ + + W L+ LP + RQ + C P + +++
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDC--------TLTFSHPTWYWENLLKI 236
Query: 235 TALLF-FCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRR 293
+F F +P+ I++V Y L+ LRL+ R+L GS ++ DR R
Sbjct: 237 CVFIFAFIMPVLIITVCYGLMILRLKSVRML-------SGS-----------KEKDRNLR 278
Query: 294 QVTKMLFVLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANP 353
++T+M+ V+V VF +CW P H ++ ++V+ H + G Y S NP
Sbjct: 279 RITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALG---YTNSCLNP 335
Query: 354 VLYSLMSSRFRETFQE 369
VLY+ + F+ F+E
Sbjct: 336 VLYAFLDENFKRCFRE 351
>gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]
Length = 420
Score = 109 bits (273), Expect = 4e-24
Identities = 103/376 (27%), Positives = 168/376 (44%), Gaps = 58/376 (15%)
Query: 7 NCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELFMP---I 63
+CS P PG N +G+ + DP N TD R P + + I
Sbjct: 21 SCSPAPS---PGSWVNLSHLDGNLS----DPCGPNRTDLGGRDSLCPPTGSPSMITAITI 73
Query: 64 CATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWH 123
A Y ++ VVG GN L VI+R+ M+T TN Y+F+LA++D L LP +
Sbjct: 74 MALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST-LPFQ------ 126
Query: 124 NYPFLLGVGGCYFRTLLFEMV-------CLASVLNVTALSVERYVAVVHPLQARSMVTRA 176
+ +L+G F T+L ++V S+ + +SV+RY+AV HP++A T
Sbjct: 127 SVNYLMGTWP--FGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 184
Query: 177 HVRRVLGAVWGLAMLCSLP--NTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQT 234
+ + + W L+ LP + RQ + C P + +++
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDC--------TLTFSHPTWYWENLLKI 236
Query: 235 TALLF-FCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRR 293
+F F +P+ I++V Y L+ LRL+ R+L GS ++ DR R
Sbjct: 237 CVFIFAFIMPVLIITVCYGLMILRLKSVRML-------SGS-----------KEKDRNLR 278
Query: 294 QVTKMLFVLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANP 353
++T+M+ V+V VF +CW P H ++ ++V+ H + G Y S NP
Sbjct: 279 RITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALG---YTNSCLNP 335
Query: 354 VLYSLMSSRFRETFQE 369
VLY+ + F+ F+E
Sbjct: 336 VLYAFLDENFKRCFRE 351
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.328 0.140 0.449
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,582,861
Number of Sequences: 37866
Number of extensions: 704244
Number of successful extensions: 4009
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 475
Number of HSP's successfully gapped in prelim test: 278
Number of HSP's that attempted gapping in prelim test: 2264
Number of HSP's gapped (non-prelim): 1017
length of query: 426
length of database: 18,247,518
effective HSP length: 105
effective length of query: 321
effective length of database: 14,271,588
effective search space: 4581179748
effective search space used: 4581179748
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.