Search of human proteins with 11321636

Search of human proteins with 11321636

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11321636 tryptase delta 1 [Homo sapiens]
         (242 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11321636 tryptase delta 1 [Homo sapiens]                           513   e-146
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]            437   e-123
gi|68508970 tryptase beta 2 precursor [Homo sapiens]                  432   e-121
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]      176   1e-44
gi|117956391 protease, serine, 33 [Homo sapiens]                      165   4e-41
gi|4506153 prostasin preproprotein [Homo sapiens]                     163   1e-40
gi|13994276 marapsin [Homo sapiens]                                   163   1e-40
gi|11545839 protease, serine, 22 [Homo sapiens]                       155   2e-38
gi|21614531 testisin isoform 2 [Homo sapiens]                         147   1e-35
gi|58218970 protease, serine, 36 [Homo sapiens]                       142   2e-34
gi|5803197 testisin isoform 1 [Homo sapiens]                          142   3e-34
gi|148806900 epidermis-specific serine protease-like protein [Ho...   140   1e-33
gi|15559207 elastase 2A preproprotein [Homo sapiens]                  139   2e-33
gi|58331211 elastase 2B preproprotein [Homo sapiens]                  139   2e-33
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap...   137   1e-32
gi|23957702 transmembrane protease, serine 6 [Homo sapiens]           137   1e-32
gi|118498341 chymotrypsin B1 [Homo sapiens]                           135   2e-32
gi|118498350 chymotrypsin B2 [Homo sapiens]                           134   9e-32
gi|4503627 coagulation factor XI precursor [Homo sapiens]             133   1e-31
gi|4505881 plasminogen [Homo sapiens]                                 133   2e-31
gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]          132   3e-31
gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ...   132   3e-31
gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ...   132   3e-31
gi|58331209 chymotrypsin-like elastase family, member 1 [Homo sa...   132   4e-31
gi|205360905 testis-specific serine protease 1 [Homo sapiens]         131   6e-31
gi|116256363 transmembrane protease, serine 13 [Homo sapiens]         131   6e-31
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa...   130   8e-31
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa...   130   8e-31
gi|236460050 elastase 3A, pancreatic preproprotein [Homo sapiens]     130   1e-30
gi|4503137 chymotrypsin-like [Homo sapiens]                           130   1e-30

>gi|11321636 tryptase delta 1 [Homo sapiens]
          Length = 242

 Score =  513 bits (1321), Expect = e-146
 Identities = 242/242 (100%), Positives = 242/242 (100%)

Query: 1   MLLLAPQMLSLLLLALPVLASPAYVAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRVRGP 60
           MLLLAPQMLSLLLLALPVLASPAYVAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRVRGP
Sbjct: 1   MLLLAPQMLSLLLLALPVLASPAYVAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRVRGP 60

Query: 61  YWMHFCGGSLIHPQWVLTAAHCVEPDIKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQF 120
           YWMHFCGGSLIHPQWVLTAAHCVEPDIKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQF
Sbjct: 61  YWMHFCGGSLIHPQWVLTAAHCVEPDIKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQF 120

Query: 121 YIIQTGADIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPY 180
           YIIQTGADIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPY
Sbjct: 121 YIIQTGADIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPY 180

Query: 181 PLKEVEVPVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAGSENHDSCQGDSGGPLVCKVN 240
           PLKEVEVPVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAGSENHDSCQGDSGGPLVCKVN
Sbjct: 181 PLKEVEVPVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAGSENHDSCQGDSGGPLVCKVN 240

Query: 241 GT 242
           GT
Sbjct: 241 GT 242


>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
          Length = 275

 Score =  437 bits (1123), Expect = e-123
 Identities = 200/235 (85%), Positives = 217/235 (92%)

Query: 8   MLSLLLLALPVLASPAYVAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRVRGPYWMHFCG 67
           ML+LLLLALPVLAS AY APAPGQALQ+ GIVGGQEAPRSKWPWQVSLRV GPYWMHFCG
Sbjct: 1   MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCG 60

Query: 68  GSLIHPQWVLTAAHCVEPDIKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYIIQTGA 127
           GSLIHPQWVLTAAHCV PD+KDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFY  Q GA
Sbjct: 61  GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA 120

Query: 128 DIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEV 187
           DIALLELEEPVN+SSH+HTVTLPPASETFPPGMPCWVTGWGDVDN+  LPPP+PLK+V+V
Sbjct: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180

Query: 188 PVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAGSENHDSCQGDSGGPLVCKVNGT 242
           P++ENH+C+A+YH G +TG   +IVRDDMLCAG+   DSCQGDSGGPLVCKVNGT
Sbjct: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGT 235


>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
          Length = 275

 Score =  432 bits (1112), Expect = e-121
 Identities = 199/235 (84%), Positives = 216/235 (91%)

Query: 8   MLSLLLLALPVLASPAYVAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRVRGPYWMHFCG 67
           ML+LLLLALPVLAS AY APAPGQALQ+ GIVGGQEAPRSKWPWQVSLRVR  YWMHFCG
Sbjct: 1   MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCG 60

Query: 68  GSLIHPQWVLTAAHCVEPDIKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYIIQTGA 127
           GSLIHPQWVLTAAHCV PD+KDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFY  Q GA
Sbjct: 61  GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA 120

Query: 128 DIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEV 187
           DIALLELEEPVN+SSH+HTVTLPPASETFPPGMPCWVTGWGDVDN+  LPPP+PLK+V+V
Sbjct: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180

Query: 188 PVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAGSENHDSCQGDSGGPLVCKVNGT 242
           P++ENH+C+A+YH G +TG   +IVRDDMLCAG+   DSCQGDSGGPLVCKVNGT
Sbjct: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGT 235


>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
          Length = 321

 Score =  176 bits (447), Expect = 1e-44
 Identities = 105/234 (44%), Positives = 130/234 (55%), Gaps = 13/234 (5%)

Query: 11  LLLLALPVLASPAYVAPAPGQALQQTG--IVGGQEAPRSKWPWQVSLRVRGPYWMHFCGG 68
           LLLLA+P ++            +   G  IVGG  AP   WPWQ SLR+R    +H CGG
Sbjct: 9   LLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRR---VHVCGG 65

Query: 69  SLIHPQWVLTAAHCVEPDIKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQ-FYIIQTGA 127
           SL+ PQWVLTAAHC    +   +  +V L E  +        V +II+H        T  
Sbjct: 66  SLLSPQWVLTAAHCFSGSLNS-SDYQVHLGELEITLSPHFSTVRQIILHSSPSGQPGTSG 124

Query: 128 DIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEV 187
           DIAL+EL  PV +SS I  V LP AS+ F PG+ CWVTGWG       LPPPY L+EV+V
Sbjct: 125 DIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKV 184

Query: 188 PVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAGSENHDSCQGDSGGPLVCKVNG 241
            VV+   C  +Y      G    I++ DMLCA     D+CQ DSGGPLVC+VNG
Sbjct: 185 SVVDTETCRRDY-----PGPGGSILQPDMLCARGPG-DACQDDSGGPLVCQVNG 232


>gi|117956391 protease, serine, 33 [Homo sapiens]
          Length = 280

 Score =  165 bits (417), Expect = 4e-41
 Identities = 97/237 (40%), Positives = 129/237 (54%), Gaps = 9/237 (3%)

Query: 11  LLLLALPVLASPAYVAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSL 70
           LLLL L    +    + A GQ    + IVGG++    +WPWQ S++ RG    H CGGSL
Sbjct: 10  LLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGA---HVCGGSL 66

Query: 71  IHPQWVLTAAHCVEPDIKDLAALRVQLREQHLYYQDQL---LPVSRIIVHPQFYIIQTGA 127
           I PQWVLTAAHC  P     A  RV+L    L         +PV R+++ P +       
Sbjct: 67  IAPQWVLTAAHCF-PRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARG 125

Query: 128 DIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEV 187
           D+ALL+L  PV +S+ +  V LP      PPG PC VTGWG +   V LP   PL+ V V
Sbjct: 126 DLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRV 185

Query: 188 PVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAG--SENHDSCQGDSGGPLVCKVNGT 242
           P++++  C+  YH G     + +IV    LCAG    + D+CQGDSGGPL C  +G+
Sbjct: 186 PLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGS 242


>gi|4506153 prostasin preproprotein [Homo sapiens]
          Length = 343

 Score =  163 bits (413), Expect = 1e-40
 Identities = 97/236 (41%), Positives = 128/236 (54%), Gaps = 10/236 (4%)

Query: 11  LLLLALPVLASPAYVAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSL 70
           LL L L    + A  A AP     Q  I GG  A   +WPWQVS+   G   +H CGGSL
Sbjct: 18  LLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEG---VHVCGGSL 74

Query: 71  IHPQWVLTAAHCVEPDIKDLAALRVQLREQHL--YYQD-QLLPVSRIIVHPQFYIIQTGA 127
           +  QWVL+AAHC  P      A  V+L    L  Y +D ++  +  II HP +    +  
Sbjct: 75  VSEQWVLSAAHCF-PSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQG 133

Query: 128 DIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEV 187
           DIALL+L  P+  S +I  + LP A+ +FP G+ C VTGWG V  +V L  P PL+++EV
Sbjct: 134 DIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEV 193

Query: 188 PVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAG--SENHDSCQGDSGGPLVCKVNG 241
           P++    CN  Y+           V++DM+CAG      D+CQGDSGGPL C V G
Sbjct: 194 PLISRETCNCLYNIDAKPEEP-HFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEG 248


>gi|13994276 marapsin [Homo sapiens]
          Length = 290

 Score =  163 bits (413), Expect = 1e-40
 Identities = 94/233 (40%), Positives = 129/233 (55%), Gaps = 9/233 (3%)

Query: 12  LLLALPVLASPAYVAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSLI 71
           LLL L   +  A  A A G+      +VGGQ+    +WPWQVS++  G    HFCGGSLI
Sbjct: 9   LLLLLCFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGS---HFCGGSLI 65

Query: 72  HPQWVLTAAHCVEPDIKDLAALRVQLREQHLYYQD---QLLPVSRIIVHPQFYIIQTGAD 128
             QWVLTAAHC   +  + +  +V L  + L           V ++  +P +    + AD
Sbjct: 66  AEQWVLTAAHCFR-NTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSAD 124

Query: 129 IALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEVP 188
           +AL+ELE PV  +++I  V LP  S  F  GM CWVTGWG       LP P  L+++ VP
Sbjct: 125 VALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVP 184

Query: 189 VVENHLCNAEYHTGLHTGHSFQIVRDDMLCAGSE--NHDSCQGDSGGPLVCKV 239
           +++   CN  Y      G+  + +++DMLCAG E    D+C+GDSGGPLVC V
Sbjct: 185 IIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLV 237


>gi|11545839 protease, serine, 22 [Homo sapiens]
          Length = 317

 Score =  155 bits (393), Expect = 2e-38
 Identities = 91/241 (37%), Positives = 136/241 (56%), Gaps = 17/241 (7%)

Query: 10  SLLLLALPVLASPAY--VAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRVRGPYWMHFCG 67
           SLLLLA   + + A   V PA G+  Q   +VGG+++  S+WPW VS++  G    H C 
Sbjct: 20  SLLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGT---HHCA 76

Query: 68  GSLIHPQWVLTAAHCVEPDIKDLAALRVQLREQHLYY---QDQLLPVSRIIVHPQFYIIQ 124
           GSL+  +WV+TAAHC + ++       V L    L     + Q + V+ +  HP  Y  +
Sbjct: 77  GSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEPHP-VYSWK 135

Query: 125 TGA--DIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPYPL 182
            GA  DIAL+ LE  +  S  +  + LP AS   PP   CW++GWG + + V LP P  L
Sbjct: 136 EGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTL 195

Query: 183 KEVEVPVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAG--SENHDSCQGDSGGPLVCKVN 240
           ++++VP++++ +C+  Y  G   G     + +DMLCAG      D+C GDSGGPL+C+V+
Sbjct: 196 QKLKVPIIDSEVCSHLYWRGAGQGP----ITEDMLCAGYLEGERDACLGDSGGPLMCQVD 251

Query: 241 G 241
           G
Sbjct: 252 G 252


>gi|21614531 testisin isoform 2 [Homo sapiens]
          Length = 312

 Score =  147 bits (370), Expect = 1e-35
 Identities = 94/251 (37%), Positives = 132/251 (52%), Gaps = 28/251 (11%)

Query: 8   MLSLLLLALPVLASPAYVAPAP-----GQALQQTGIVGGQEAPRSKWPWQVSLRVRGPYW 62
           +L  LLLA   L  P     AP     G+ +  + IVGG++A   +WPWQ SLR+   + 
Sbjct: 7   LLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRL---WD 63

Query: 63  MHFCGGSLIHPQWVLTAAHCVEPDIKDLAALRVQLRE---------QHLYYQDQLLPVSR 113
            H CG SL+  +W LTAAHC E D+ D +   VQ  +            YY      VS 
Sbjct: 64  SHVCGVSLLSHRWALTAAHCFETDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF--VSN 121

Query: 114 IIVHPQFYIIQTGADIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNN 173
           I + P+ Y+  +  DIAL++L  PV  + HI  + L  ++  F     CWVTGWG +  +
Sbjct: 122 IYLSPR-YLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKED 180

Query: 174 VHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSF-QIVRDDMLCAGSE--NHDSCQGD 230
             LP P+ L+EV+V ++ N +CN      L   +SF + +  DM+CAG+     D+C GD
Sbjct: 181 EALPSPHTLQEVQVAIINNSMCN-----HLFLKYSFRKDIFGDMVCAGNAQGGKDACFGD 235

Query: 231 SGGPLVCKVNG 241
           SGGPL C  NG
Sbjct: 236 SGGPLACNKNG 246


>gi|58218970 protease, serine, 36 [Homo sapiens]
          Length = 855

 Score =  142 bits (359), Expect = 2e-34
 Identities = 88/212 (41%), Positives = 111/212 (52%), Gaps = 13/212 (6%)

Query: 38  IVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSLIHPQWVLTAAHC------VEPDIKDLA 91
           IVGG  A    WPWQVSL   G    H CGGSLI P WVL+AAHC      +EP  +   
Sbjct: 47  IVGGSNAQPGTWPWQVSLHHGGG---HICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSV 103

Query: 92  ALRVQLREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSHIHTVTLPP 151
            L V  ++  L        V+ I+V   +  ++ GAD+ALL L  P ++   +  V LP 
Sbjct: 104 LLGVHSQDGPLDGA-HTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWPVCLPR 162

Query: 152 ASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSFQI 211
           AS  F  G  CW TGWGDV     LP P+ L+EVE+ ++    C   Y        + QI
Sbjct: 163 ASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQI 222

Query: 212 VRDDMLCAG--SENHDSCQGDSGGPLVCKVNG 241
           +   MLCAG      D+CQGDSGGPLVC+  G
Sbjct: 223 L-PGMLCAGYPEGRRDTCQGDSGGPLVCEEGG 253



 Score = 67.8 bits (164), Expect = 8e-12
 Identities = 57/195 (29%), Positives = 81/195 (41%), Gaps = 25/195 (12%)

Query: 49  WPWQVSLRVRGPYWMHFCGGSLIHPQWVLTAAHCV-EPDIKDLAALRVQLREQHLYYQDQ 107
           WPW   + V G      C G L+ P WVL A HCV  P    +  + V L         Q
Sbjct: 601 WPWLAEVHVAGD---RVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQ 657

Query: 108 LLPVSRIIVH---PQFYIIQTGADIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWV 164
              VSR+++    PQ   ++    +ALLEL   V  S     + L PA    PPG  CWV
Sbjct: 658 GHQVSRLVISIRLPQHLGLR--PPLALLELSSRVEPSPSALPICLHPAG--IPPGASCWV 713

Query: 165 TGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAGSENH 224
            GW +  + V +          V ++   +C+  Y   L  G    +  +     G EN 
Sbjct: 714 LGWKEPQDRVPV-------AAAVSILTQRICDCLYQGILPPGTLCVLYAE-----GQENR 761

Query: 225 DSCQGDSGGPLVCKV 239
             C+  S  PL+C++
Sbjct: 762 --CEMTSAPPLLCQM 774



 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 58/207 (28%), Positives = 87/207 (42%), Gaps = 19/207 (9%)

Query: 43  EAPR-SKWPWQVSLRVRGPYWMHFCGGSLIHPQWVLTAAHC-VEPDIKDLAALRVQLREQ 100
           +APR   WPW+  + V G      C G+L+   WVL  A C ++P+  D     +     
Sbjct: 327 KAPRPGAWPWEAQVMVPGS---RPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRV 383

Query: 101 HLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSHIHTVTLPPASETFPPGM 160
            L  + +   V+R++ H         +D+ALL+L  PVN+S+    V LP     F PG 
Sbjct: 384 LLPSRPRAERVARLVQHENASW-DNASDLALLQLRTPVNLSAASRPVCLPHPEHYFLPGS 442

Query: 161 PCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSFQIVRD--DMLC 218
            C +  WG  +     P   P   +E  ++    C+  Y      G +  +  D    LC
Sbjct: 443 RCRLARWGRGE-----PALGPGALLEAELLGGWWCHCLYG---RQGAAVPLPGDPPHALC 494

Query: 219 AG---SENHDSCQGDSGGPLVCKVNGT 242
                 E   SC  DS   L+C+  GT
Sbjct: 495 PAYQEKEEVGSCWNDSRWSLLCQEEGT 521


>gi|5803197 testisin isoform 1 [Homo sapiens]
          Length = 314

 Score =  142 bits (357), Expect = 3e-34
 Identities = 94/253 (37%), Positives = 132/253 (52%), Gaps = 30/253 (11%)

Query: 8   MLSLLLLALPVLASPAYVAPAP-----GQALQQTGIVGGQEAPRSKWPWQVSLRVRGPYW 62
           +L  LLLA   L  P     AP     G+ +  + IVGG++A   +WPWQ SLR+   + 
Sbjct: 7   LLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRL---WD 63

Query: 63  MHFCGGSLIHPQWVLTAAHCVE--PDIKDLAALRVQLRE---------QHLYYQDQLLPV 111
            H CG SL+  +W LTAAHC E   D+ D +   VQ  +            YY      V
Sbjct: 64  SHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF--V 121

Query: 112 SRIIVHPQFYIIQTGADIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVD 171
           S I + P+ Y+  +  DIAL++L  PV  + HI  + L  ++  F     CWVTGWG + 
Sbjct: 122 SNIYLSPR-YLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIK 180

Query: 172 NNVHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSF-QIVRDDMLCAGSE--NHDSCQ 228
            +  LP P+ L+EV+V ++ N +CN      L   +SF + +  DM+CAG+     D+C 
Sbjct: 181 EDEALPSPHTLQEVQVAIINNSMCN-----HLFLKYSFRKDIFGDMVCAGNAQGGKDACF 235

Query: 229 GDSGGPLVCKVNG 241
           GDSGGPL C  NG
Sbjct: 236 GDSGGPLACNKNG 248


>gi|148806900 epidermis-specific serine protease-like protein [Homo
           sapiens]
          Length = 328

 Score =  140 bits (353), Expect = 1e-33
 Identities = 85/241 (35%), Positives = 127/241 (52%), Gaps = 31/241 (12%)

Query: 11  LLLLALPVLASPAYVAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSL 70
           LLLL + V   P Y           + +VGGQ+A   +WPWQVSL     +    CGGSL
Sbjct: 11  LLLLGISVCGQPVY----------SSRVVGGQDAAAGRWPWQVSLHFDHNF---ICGGSL 57

Query: 71  IHPQWVLTAAHCVEPDIKD------LAALRV-QLREQHLYYQDQLLPVSRIIVHPQFYII 123
           +  + +LTAAHC++P          L ++ V   R++  YY      VS+I++HP++   
Sbjct: 58  VSERLILTAAHCIQPTWTTFSYTVWLGSITVGDSRKRVKYY------VSKIVIHPKYQ-- 109

Query: 124 QTGADIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPYPLK 183
            T AD+ALL+L   V  +S I  + LP  ++       CWVTGWG V  +        L+
Sbjct: 110 DTTADVALLKLSSQVTFTSAILPICLPSVTKQLAIPPFCWVTGWGKVKESSDRDYHSALQ 169

Query: 184 EVEVPVVENHLCNAEYH-TGLHTGHSFQIVRDDMLCAGSENH--DSCQGDSGGPLVCKVN 240
           E EVP+++   C   Y+  G+       ++++D +CAG   +  DSC+GDSGGPL C ++
Sbjct: 170 EAEVPIIDRQACEQLYNPIGIFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHID 229

Query: 241 G 241
           G
Sbjct: 230 G 230


>gi|15559207 elastase 2A preproprotein [Homo sapiens]
          Length = 269

 Score =  139 bits (350), Expect = 2e-33
 Identities = 89/234 (38%), Positives = 119/234 (50%), Gaps = 20/234 (8%)

Query: 14  LALPVLASPAYVAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRVRGP-YWMHFCGGSLIH 72
           L L  L + A     P      T +VGG+EA  + WPWQVSL+      W H CGGSLI 
Sbjct: 5   LLLSTLVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIA 64

Query: 73  PQWVLTAAHCVEPDIKDLAALRVQLREQHLYYQDQ---LLPVSRIIVHPQFYI--IQTGA 127
             WVLTAAHC+          RV L   +LY  +     + VS+I+VH  +    I  G 
Sbjct: 65  NSWVLTAAHCISSS----RTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGN 120

Query: 128 DIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEV 187
           DIALL+L  PV+++  I    LPPA    P   PC+VTGWG +  N  +P    L++  +
Sbjct: 121 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPD--VLQQGRL 178

Query: 188 PVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAGSEN-HDSCQGDSGGPLVCKVN 240
            VV+   C++    G         V+  M+CAG +    SC GDSGGPL C+ +
Sbjct: 179 LVVDYATCSSSAWWG-------SSVKTSMICAGGDGVISSCNGDSGGPLNCQAS 225


>gi|58331211 elastase 2B preproprotein [Homo sapiens]
          Length = 269

 Score =  139 bits (350), Expect = 2e-33
 Identities = 88/234 (37%), Positives = 122/234 (52%), Gaps = 20/234 (8%)

Query: 14  LALPVLASPAYVAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRVRGP-YWMHFCGGSLIH 72
           L L  L + A        A   + ++GG+EA  + WPWQVSL+      W H CGGSLI 
Sbjct: 5   LLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIA 64

Query: 73  PQWVLTAAHCVEPDIKDLAALRVQLREQHLYYQDQ---LLPVSRIIVHPQFYIIQT--GA 127
             WVLTAAHC+          RV L + +LY  +     + VS+I+VH  +   Q   G 
Sbjct: 65  NSWVLTAAHCISSS----GIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGN 120

Query: 128 DIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEV 187
           DIALL+L  PV+++  I    LPPA    P   PC+VTGWG +  N  LP    LK+  +
Sbjct: 121 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPD--DLKQGRL 178

Query: 188 PVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAGSEN-HDSCQGDSGGPLVCKVN 240
            VV+   C++       +G     V+ +M+CAG +    +C GDSGGPL C+ +
Sbjct: 179 LVVDYATCSS-------SGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQAS 225


>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
           sapiens]
          Length = 454

 Score =  137 bits (344), Expect = 1e-32
 Identities = 82/206 (39%), Positives = 114/206 (55%), Gaps = 19/206 (9%)

Query: 38  IVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSLIHPQWVLTAAHCVEPDIKDLAALRVQL 97
           IVGG  +  S+WPWQ SL+ +G    H CGGS+I P W++TAAHCV  D+    +  +Q+
Sbjct: 217 IVGGNMSLLSQWPWQASLQFQG---YHLCGGSVITPLWIITAAHCVY-DLYLPKSWTIQV 272

Query: 98  REQHLYYQDQLLP---VSRIIVHPQFYIIQTGADIALLELEEPVNISSHIHTVTLPPASE 154
               L   D   P   V +I+ H ++   + G DIAL++L  P+  +  I  V LP + E
Sbjct: 273 GLVSLL--DNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEE 330

Query: 155 TFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSFQIVRD 214
            FP G  CW +GWG  ++      P  L    VP++ N +CN   H  ++ G    I+  
Sbjct: 331 NFPDGKVCWTSGWGATEDGAGDASPV-LNHAAVPLISNKICN---HRDVYGG----IISP 382

Query: 215 DMLCAG--SENHDSCQGDSGGPLVCK 238
            MLCAG  +   DSCQGDSGGPLVC+
Sbjct: 383 SMLCAGYLTGGVDSCQGDSGGPLVCQ 408


>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
          Length = 811

 Score =  137 bits (344), Expect = 1e-32
 Identities = 81/207 (39%), Positives = 112/207 (54%), Gaps = 20/207 (9%)

Query: 38  IVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSLIHPQWVLTAAHCVEPDIKDLAALRV-- 95
           IVGG  +   +WPWQ SL+VRG    H CGG+LI  +WV+TAAHC + D      L    
Sbjct: 577 IVGGAVSSEGEWPWQASLQVRG---RHICGGALIADRWVITAAHCFQEDSMASTVLWTVF 633

Query: 96  --QLREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSHIHTVTLPPAS 153
             ++ +   +  +    VSR+++HP         D+ALL+L+ PV  S+ +  V LP  S
Sbjct: 634 LGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARS 693

Query: 154 ETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSFQIVR 213
             F PG+ CW+TGWG +      P    L++V+V ++   LC+  Y         +Q V 
Sbjct: 694 HFFEPGLHCWITGWGALREGG--PISNALQKVDVQLIPQDLCSEVYR--------YQ-VT 742

Query: 214 DDMLCAG--SENHDSCQGDSGGPLVCK 238
             MLCAG      D+CQGDSGGPLVCK
Sbjct: 743 PRMLCAGYRKGKKDACQGDSGGPLVCK 769


>gi|118498341 chymotrypsin B1 [Homo sapiens]
          Length = 263

 Score =  135 bits (341), Expect = 2e-32
 Identities = 84/239 (35%), Positives = 121/239 (50%), Gaps = 21/239 (8%)

Query: 8   MLSLLLLALPVLASPAYVAPAPGQALQQTG---IVGGQEAPRSKWPWQVSLRVRGPYWMH 64
           M SL LL+   L   A+    P      +G   IV G++A    WPWQVSL+ +  +  H
Sbjct: 1   MASLWLLSCFSLVGAAFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTGF--H 58

Query: 65  FCGGSLIHPQWVLTAAHCV--EPDIKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYI 122
           FCGGSLI   WV+TAAHC     D+           E+++    Q+L ++++  +P+F I
Sbjct: 59  FCGGSLISEDWVVTAAHCGVRTSDVVVAGEFDQGSDEENI----QVLKIAKVFKNPKFSI 114

Query: 123 IQTGADIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPYPL 182
           +    DI LL+L  P   S  +  V LP A + FP G  C  TGWG    N +  P   L
Sbjct: 115 LTVNNDITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPD-KL 173

Query: 183 KEVEVPVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAGSENHDSCQGDSGGPLVCKVNG 241
           ++  +P++ N  C   +          + + D M+CAG+    SC GDSGGPLVC+ +G
Sbjct: 174 QQAALPLLSNAECKKSWG---------RRITDVMICAGASGVSSCMGDSGGPLVCQKDG 223


>gi|118498350 chymotrypsin B2 [Homo sapiens]
          Length = 263

 Score =  134 bits (336), Expect = 9e-32
 Identities = 75/206 (36%), Positives = 109/206 (52%), Gaps = 18/206 (8%)

Query: 38  IVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSLIHPQWVLTAAHCV--EPDIKDLAALRV 95
           IV G++A    WPWQVSL+ +  +  HFCGGSLI   WV+TAAHC     D+        
Sbjct: 34  IVNGEDAVPGSWPWQVSLQDKTGF--HFCGGSLISEDWVVTAAHCGVRTSDVVVAGEFDQ 91

Query: 96  QLREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSHIHTVTLPPASET 155
              E+++    Q+L ++++  +P+F I+    DI LL+L  P   S  +  V LP A + 
Sbjct: 92  GSDEENI----QVLKIAKVFKNPKFSILTVNNDITLLKLATPARFSQTVSAVCLPSADDD 147

Query: 156 FPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSFQIVRDD 215
           FP G  C  TGWG    N +  P   L++  +P++ N  C   +          + + D 
Sbjct: 148 FPAGTLCATTGWGKTKYNANKTPD-KLQQAALPLLSNAECKKSWG---------RRITDV 197

Query: 216 MLCAGSENHDSCQGDSGGPLVCKVNG 241
           M+CAG+    SC GDSGGPLVC+ +G
Sbjct: 198 MICAGASGVSSCMGDSGGPLVCQKDG 223


>gi|4503627 coagulation factor XI precursor [Homo sapiens]
          Length = 625

 Score =  133 bits (335), Expect = 1e-31
 Identities = 78/208 (37%), Positives = 106/208 (50%), Gaps = 16/208 (7%)

Query: 38  IVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSLIHPQWVLTAAHCVEPDIKDLAALRVQ- 96
           IVGG  + R +WPWQV+L    P   H CGGS+I  QW+LTAAHC    ++    LRV  
Sbjct: 388 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFY-GVESPKILRVYS 446

Query: 97  --LREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSHIHTVTLPPASE 154
             L +  +        V  II+H Q+ + ++G DIALL+LE  VN +     + LP   +
Sbjct: 447 GILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGD 506

Query: 155 TFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSFQIVRD 214
                  CWVTGWG     +       L++ ++P+V N  C   Y      GH    +  
Sbjct: 507 RNVIYTDCWVTGWG--YRKLRDKIQNTLQKAKIPLVTNEECQKRYR-----GHK---ITH 556

Query: 215 DMLCAG--SENHDSCQGDSGGPLVCKVN 240
            M+CAG      D+C+GDSGGPL CK N
Sbjct: 557 KMICAGYREGGKDACKGDSGGPLSCKHN 584


>gi|4505881 plasminogen [Homo sapiens]
          Length = 810

 Score =  133 bits (334), Expect = 2e-31
 Identities = 84/205 (40%), Positives = 109/205 (53%), Gaps = 24/205 (11%)

Query: 38  IVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSLIHPQWVLTAAHCVE--PDIKDLAALRV 95
           +VGG  A    WPWQVSLR R  + MHFCGG+LI P+WVLTAAHC+E  P       +  
Sbjct: 581 VVGGCVAHPHSWPWQVSLRTR--FGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILG 638

Query: 96  QLREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSHIHTVTLPPASET 155
             +E +L    Q + VSR+ + P      T  DIALL+L  P  I+  +    LP  +  
Sbjct: 639 AHQEVNLEPHVQEIEVSRLFLEP------TRKDIALLKLSSPAVITDKVIPACLPSPNYV 692

Query: 156 FPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNA-EYHTGLHTGHSFQIVRD 214
                 C++TGWG+            LKE ++PV+EN +CN  E+  G         V+ 
Sbjct: 693 VADRTECFITGWGETQGTFGAG---LLKEAQLPVIENKVCNRYEFLNGR--------VQS 741

Query: 215 DMLCAG--SENHDSCQGDSGGPLVC 237
             LCAG  +   DSCQGDSGGPLVC
Sbjct: 742 TELCAGHLAGGTDSCQGDSGGPLVC 766


>gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]
          Length = 410

 Score =  132 bits (332), Expect = 3e-31
 Identities = 84/212 (39%), Positives = 105/212 (49%), Gaps = 20/212 (9%)

Query: 38  IVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSLIHPQWVLTAAHCV------EPDIKDLA 91
           ++GG  AP  KWPWQVSL+      +H CGGSLI  +WVLTAAHCV      E     LA
Sbjct: 163 MIGGLPAPNKKWPWQVSLQTSN---IHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLA 219

Query: 92  AL-RVQLREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSHIHTVTLP 150
            + R     +HL           II    F      +DIAL  L   VN SSHI    LP
Sbjct: 220 GIGRWDQAWKHL---------EDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLP 270

Query: 151 PASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSFQ 210
                   G  CWVTGWG V  +V  P P  L+E E+ ++ +  C  E     +   S  
Sbjct: 271 EKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKC-CEMLKNKNISKSKM 329

Query: 211 IVRDDMLCAGSENHDSCQGDSGGPLVCKVNGT 242
           + R  +     +  D+CQGDSGGPLVC++NGT
Sbjct: 330 VTRGTVCGYNDQGKDACQGDSGGPLVCELNGT 361


>gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo
           sapiens]
          Length = 410

 Score =  132 bits (332), Expect = 3e-31
 Identities = 84/212 (39%), Positives = 105/212 (49%), Gaps = 20/212 (9%)

Query: 38  IVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSLIHPQWVLTAAHCV------EPDIKDLA 91
           ++GG  AP  KWPWQVSL+      +H CGGSLI  +WVLTAAHCV      E     LA
Sbjct: 163 MIGGLPAPNKKWPWQVSLQTSN---IHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLA 219

Query: 92  AL-RVQLREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSHIHTVTLP 150
            + R     +HL           II    F      +DIAL  L   VN SSHI    LP
Sbjct: 220 GIGRWDQAWKHL---------EDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLP 270

Query: 151 PASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSFQ 210
                   G  CWVTGWG V  +V  P P  L+E E+ ++ +  C  E     +   S  
Sbjct: 271 EKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKC-CEMLKNKNISKSKM 329

Query: 211 IVRDDMLCAGSENHDSCQGDSGGPLVCKVNGT 242
           + R  +     +  D+CQGDSGGPLVC++NGT
Sbjct: 330 VTRGTVCGYNDQGKDACQGDSGGPLVCELNGT 361


>gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo
           sapiens]
          Length = 410

 Score =  132 bits (332), Expect = 3e-31
 Identities = 84/212 (39%), Positives = 105/212 (49%), Gaps = 20/212 (9%)

Query: 38  IVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSLIHPQWVLTAAHCV------EPDIKDLA 91
           ++GG  AP  KWPWQVSL+      +H CGGSLI  +WVLTAAHCV      E     LA
Sbjct: 163 MIGGLPAPNKKWPWQVSLQTSN---IHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLA 219

Query: 92  AL-RVQLREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSHIHTVTLP 150
            + R     +HL           II    F      +DIAL  L   VN SSHI    LP
Sbjct: 220 GIGRWDQAWKHL---------EDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLP 270

Query: 151 PASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSFQ 210
                   G  CWVTGWG V  +V  P P  L+E E+ ++ +  C  E     +   S  
Sbjct: 271 EKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKC-CEMLKNKNISKSKM 329

Query: 211 IVRDDMLCAGSENHDSCQGDSGGPLVCKVNGT 242
           + R  +     +  D+CQGDSGGPLVC++NGT
Sbjct: 330 VTRGTVCGYNDQGKDACQGDSGGPLVCELNGT 361


>gi|58331209 chymotrypsin-like elastase family, member 1 [Homo
           sapiens]
          Length = 258

 Score =  132 bits (331), Expect = 4e-31
 Identities = 79/211 (37%), Positives = 112/211 (53%), Gaps = 20/211 (9%)

Query: 38  IVGGQEAPRSKWPWQVSLRVR-GPYWMHFCGGSLIHPQWVLTAAHCVEPDIKDLAALRVQ 96
           +VGG EA R+ WP Q+SL+ R G    H CGG+LI   WV+TAAHCV+         RV 
Sbjct: 19  VVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQ----KTFRVV 74

Query: 97  LREQHLYYQD---QLLPVSRIIVHPQFYI--IQTGADIALLELEEPVNISSHIHTVTLPP 151
             + +L   D   Q + V +I+VHP +    +  G DIALL L + V ++S++    LP 
Sbjct: 75  AGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQ 134

Query: 152 ASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSFQI 211
                    PC++TGWG    N  L     L++  +P V+  +C++  + G         
Sbjct: 135 EGAILANNSPCYITGWGKTKTNGQL--AQTLQQAYLPSVDYAICSSSSYWG-------ST 185

Query: 212 VRDDMLCAGSEN-HDSCQGDSGGPLVCKVNG 241
           V++ M+CAG +     CQGDSGGPL C VNG
Sbjct: 186 VKNTMVCAGGDGVRSGCQGDSGGPLHCLVNG 216


>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
          Length = 318

 Score =  131 bits (329), Expect = 6e-31
 Identities = 79/213 (37%), Positives = 112/213 (52%), Gaps = 17/213 (7%)

Query: 38  IVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSLIHPQWVLTAAHCVEPDIK------DLA 91
           + GG E+ R +WPWQ SLR+R     H CGGSL+  +WVL+AAHC +           L 
Sbjct: 55  VAGGVESARGRWPWQASLRLRR---RHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLG 111

Query: 92  ALRVQLREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSHIHTVTLPP 151
            L  +    +L        V  IIV+P    +    DIALL L   V  +++I  + +  
Sbjct: 112 ELTSRPTPWNLRAYSSRYKVQDIIVNPDALGVLRN-DIALLRLASSVTYNAYIQPICIES 170

Query: 152 ASETFPPGMPCWVTGWGDVD-NNVHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSFQ 210
           ++  F     CWVTGWG +  +   LPPPY L+E +V ++ N  CN  +        S  
Sbjct: 171 STFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLF----EQPSSRS 226

Query: 211 IVRDDMLCAGSENH--DSCQGDSGGPLVCKVNG 241
           ++ D M CAG+E+   D+C+GDSGGPLVC  +G
Sbjct: 227 MIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDG 259


>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
          Length = 567

 Score =  131 bits (329), Expect = 6e-31
 Identities = 81/206 (39%), Positives = 109/206 (52%), Gaps = 14/206 (6%)

Query: 38  IVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSLIHPQWVLTAAHCV-EPDIKDLAALRVQ 96
           IVGG  A  SKWPWQVSL        H CGG+LI  QWVLTAAHC      K L   +V 
Sbjct: 326 IVGGALASDSKWPWQVSLHFGTT---HICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVY 382

Query: 97  LREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSHIHTVTLPPASETF 156
               +L+   +   ++ II++  +   +   DIAL+ L +P+ +S+HIH   LP   +TF
Sbjct: 383 AGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTF 442

Query: 157 PPGMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSFQIVRDDM 216
                CW+TG+G          P+ L+EV+V +++   CN           S+   R  M
Sbjct: 443 SLNETCWITGFGKTRETDDKTSPF-LREVQVNLIDFKKCN-----DYLVYDSYLTPR--M 494

Query: 217 LCAGS--ENHDSCQGDSGGPLVCKVN 240
           +CAG      DSCQGDSGGPLVC+ N
Sbjct: 495 MCAGDLRGGRDSCQGDSGGPLVCEQN 520


>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
           sapiens]
          Length = 529

 Score =  130 bits (328), Expect = 8e-31
 Identities = 76/212 (35%), Positives = 110/212 (51%), Gaps = 18/212 (8%)

Query: 34  QQTGIVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSLIHPQWVLTAAHCVEPDIKD---L 90
           +Q+ IVGG+ A    WPWQVSL V+    +H CGGS+I P+W++TAAHCVE  + +    
Sbjct: 289 RQSRIVGGESALPGAWPWQVSLHVQN---VHVCGGSIITPEWIVTAAHCVEKPLNNPWHW 345

Query: 91  AALRVQLREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSHIHTVTLP 150
            A    LR+  ++Y      V ++I HP +       DIAL++L++P+  +  +  V LP
Sbjct: 346 TAFAGILRQSFMFYGAGY-QVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLP 404

Query: 151 PASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSFQ 210
                  P   CW++GWG  +          L   +V ++E   CN+ Y           
Sbjct: 405 NPGMMLQPEQLCWISGWGATEEKGKTSE--VLNAAKVLLIETQRCNSRYVYD-------N 455

Query: 211 IVRDDMLCAG--SENHDSCQGDSGGPLVCKVN 240
           ++   M+CAG    N DSCQGDSGGPLV   N
Sbjct: 456 LITPAMICAGFLQGNVDSCQGDSGGPLVTSKN 487


>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
           sapiens]
          Length = 492

 Score =  130 bits (328), Expect = 8e-31
 Identities = 76/212 (35%), Positives = 110/212 (51%), Gaps = 18/212 (8%)

Query: 34  QQTGIVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSLIHPQWVLTAAHCVEPDIKD---L 90
           +Q+ IVGG+ A    WPWQVSL V+    +H CGGS+I P+W++TAAHCVE  + +    
Sbjct: 252 RQSRIVGGESALPGAWPWQVSLHVQN---VHVCGGSIITPEWIVTAAHCVEKPLNNPWHW 308

Query: 91  AALRVQLREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSHIHTVTLP 150
            A    LR+  ++Y      V ++I HP +       DIAL++L++P+  +  +  V LP
Sbjct: 309 TAFAGILRQSFMFYGAGY-QVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLP 367

Query: 151 PASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSFQ 210
                  P   CW++GWG  +          L   +V ++E   CN+ Y           
Sbjct: 368 NPGMMLQPEQLCWISGWGATEEKGKTSE--VLNAAKVLLIETQRCNSRYVYD-------N 418

Query: 211 IVRDDMLCAG--SENHDSCQGDSGGPLVCKVN 240
           ++   M+CAG    N DSCQGDSGGPLV   N
Sbjct: 419 LITPAMICAGFLQGNVDSCQGDSGGPLVTSKN 450


>gi|236460050 elastase 3A, pancreatic preproprotein [Homo sapiens]
          Length = 270

 Score =  130 bits (327), Expect = 1e-30
 Identities = 82/238 (34%), Positives = 121/238 (50%), Gaps = 24/238 (10%)

Query: 8   MLSLLLLALPVLASPAYVAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRV-RGPYWMHFC 66
           ML LL   L V  +  Y    P  +   + +V G++A    WPWQVSL+  +   + H C
Sbjct: 2   MLRLLSSLLLVAVASGY---GPPSSHSSSRVVHGEDAVPYSWPWQVSLQYEKSGSFYHTC 58

Query: 67  GGSLIHPQWVLTAAHCVEPDIKDLAALRVQLREQHLYYQD---QLLPVS--RIIVHPQFY 121
           GGSLI P WV+TA HC+  D+      +V L E +L  ++   Q++P++   + VHP + 
Sbjct: 59  GGSLIAPDWVVTAGHCISRDL----TYQVVLGEYNLAVKEGPEQVIPINSEELFVHPLWN 114

Query: 122 --IIQTGADIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPP 179
              +  G DIAL++L     +   +   +LPPA +  P   PC++TGWG +  N   P P
Sbjct: 115 RSCVACGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNKTPCYITGWGRLYTNG--PLP 172

Query: 180 YPLKEVEVPVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAGSENHDSCQGDSGGPLVC 237
             L++  +PVV+   C+     G         V+  M+CAG      C GDSGGPL C
Sbjct: 173 DKLQQARLPVVDYKHCSRWNWWG-------STVKKTMVCAGGYIRSGCNGDSGGPLNC 223


>gi|4503137 chymotrypsin-like [Homo sapiens]
          Length = 264

 Score =  130 bits (327), Expect = 1e-30
 Identities = 87/242 (35%), Positives = 119/242 (49%), Gaps = 18/242 (7%)

Query: 2   LLLAPQMLSLLLLALPVLASPAYVAPAPGQALQ-QTGIVGGQEAPRSKWPWQVSLRVRGP 60
           +LL    LSL+LL     +S     PA   AL     IV G+ A    WPWQVSL+    
Sbjct: 1   MLLLSLTLSLVLLG----SSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSG 56

Query: 61  YWMHFCGGSLIHPQWVLTAAHCVEPDIKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQF 120
           +  HFCGGSLI   WV+TAAHC     +    L    R  +     Q+L VSR I HP +
Sbjct: 57  F--HFCGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPL-QVLSVSRAITHPSW 113

Query: 121 YIIQTGADIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPY 180
                  D+ LL+L  P   ++ I  V L  ++E    G+ C  TGWG +    ++ P +
Sbjct: 114 NSTTMNNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAH 173

Query: 181 PLKEVEVPVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAGSENHDSCQGDSGGPLVCKVN 240
            L++V +P+V  + C   + +          + D M+CAG     SCQGDSGGPLVC+  
Sbjct: 174 -LQQVALPLVTVNQCRQYWGSS---------ITDSMICAGGAGASSCQGDSGGPLVCQKG 223

Query: 241 GT 242
            T
Sbjct: 224 NT 225


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.453 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,603,315
Number of Sequences: 37866
Number of extensions: 592237
Number of successful extensions: 2128
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 163
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1542
Number of HSP's gapped (non-prelim): 197
length of query: 242
length of database: 18,247,518
effective HSP length: 99
effective length of query: 143
effective length of database: 14,498,784
effective search space: 2073326112
effective search space used: 2073326112
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.