BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|103472136 G protein-coupled receptor associated sorting protein 1 [Homo sapiens] (1395 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|150378528 G protein-coupled receptor associated sorting prote... 2846 0.0 gi|150378489 G protein-coupled receptor associated sorting prote... 2846 0.0 gi|103472136 G protein-coupled receptor associated sorting prote... 2846 0.0 gi|51702248 G protein-coupled receptor associated sorting protei... 631 e-180 gi|19923967 G protein-coupled receptor associated sorting protei... 631 e-180 gi|239757861 PREDICTED: similar to armadillo repeat containing, ... 257 6e-68 gi|216547715 basic helix-loop-helix domain containing, class B, ... 236 1e-61 gi|216547682 basic helix-loop-helix domain containing, class B, ... 236 1e-61 gi|216547672 basic helix-loop-helix domain containing, class B, ... 236 1e-61 gi|216547663 basic helix-loop-helix domain containing, class B, ... 236 1e-61 gi|216547655 basic helix-loop-helix domain containing, class B, ... 236 1e-61 gi|216547646 basic helix-loop-helix domain containing, class B, ... 236 1e-61 gi|216547639 basic helix-loop-helix domain containing, class B, ... 236 1e-61 gi|39930463 basic helix-loop-helix domain containing, class B, 9... 236 1e-61 gi|41054846 armadillo repeat containing, X-linked 5 [Homo sapiens] 197 8e-50 gi|29540566 armadillo repeat containing, X-linked 3 [Homo sapiens] 137 7e-32 gi|29540564 armadillo repeat containing, X-linked 3 [Homo sapiens] 137 7e-32 gi|7705274 armadillo repeat containing, X-linked 3 [Homo sapiens] 137 7e-32 gi|7706143 armadillo repeat containing, X-linked 1 [Homo sapiens] 134 5e-31 gi|238776793 SVH protein isoform b [Homo sapiens] 120 7e-27 gi|31377663 SVH protein isoform a [Homo sapiens] 120 7e-27 gi|7662162 ALEX2 protein [Homo sapiens] 111 6e-24 gi|29540562 ALEX2 protein [Homo sapiens] 111 6e-24 gi|169165522 PREDICTED: similar to SVH protein isoform 1 [Homo s... 86 3e-16 gi|169165931 PREDICTED: similar to SVH protein isoform 1 [Homo s... 84 1e-15 gi|113414573 PREDICTED: similar to SVH protein isoform 2 [Homo s... 84 1e-15 gi|238776797 SVH protein isoform e [Homo sapiens] 83 2e-15 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 54 1e-06 gi|169165524 PREDICTED: similar to SVH protein isoform 2 [Homo s... 52 3e-06 gi|238776799 SVH protein isoform d [Homo sapiens] 52 5e-06 >gi|150378528 G protein-coupled receptor associated sorting protein 1 [Homo sapiens] Length = 1395 Score = 2846 bits (7378), Expect = 0.0 Identities = 1395/1395 (100%), Positives = 1395/1395 (100%) Query: 1 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP 60 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP Sbjct: 1 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP 60 Query: 61 GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP 120 GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP Sbjct: 61 GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP 120 Query: 121 LVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRP 180 LVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRP Sbjct: 121 LVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRP 180 Query: 181 TSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQ 240 TSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQ Sbjct: 181 TSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQ 240 Query: 241 TNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSRSRFRSKKEVYVESSSGSE 300 TNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSRSRFRSKKEVYVESSSGSE Sbjct: 241 TNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSRSRFRSKKEVYVESSSGSE 300 Query: 301 HEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPE 360 HEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPE Sbjct: 301 HEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPE 360 Query: 361 ENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADE 420 ENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADE Sbjct: 361 ENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADE 420 Query: 421 ASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTG 480 ASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTG Sbjct: 421 ASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTG 480 Query: 481 AEATSESILAADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCES 540 AEATSESILAADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCES Sbjct: 481 AEATSESILAADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCES 540 Query: 541 RTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQTYMDCRAETSC 600 RTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQTYMDCRAETSC Sbjct: 541 RTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQTYMDCRAETSC 600 Query: 601 DTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAKEEVSMKHGTGV 660 DTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAKEEVSMKHGTGV Sbjct: 601 DTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAKEEVSMKHGTGV 660 Query: 661 RCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAII 720 RCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAII Sbjct: 661 RCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAII 720 Query: 721 GSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEATDREESRPEAEEGDIIG 780 GSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEATDREESRPEAEEGDIIG Sbjct: 721 GSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEATDREESRPEAEEGDIIG 780 Query: 781 SWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREETIRREAGSCSKSSPKAEEEE 840 SWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREETIRREAGSCSKSSPKAEEEE Sbjct: 781 SWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREETIRREAGSCSKSSPKAEEEE 840 Query: 841 VIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESE 900 VIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESE Sbjct: 841 VIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESE 900 Query: 901 TEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESK 960 TEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESK Sbjct: 901 TEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESK 960 Query: 961 PENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLADEDEAIVGSWFWAGDEAHFESNPSP 1020 PENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLADEDEAIVGSWFWAGDEAHFESNPSP Sbjct: 961 PENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLADEDEAIVGSWFWAGDEAHFESNPSP 1020 Query: 1021 VFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRFPKEAASLFCE 1080 VFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRFPKEAASLFCE Sbjct: 1021 VFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRFPKEAASLFCE 1080 Query: 1081 MFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESS 1140 MFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESS Sbjct: 1081 MFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESS 1140 Query: 1141 SCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSL 1200 SCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSL Sbjct: 1141 SCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSL 1200 Query: 1201 IETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRM 1260 IETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRM Sbjct: 1201 IETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRM 1260 Query: 1261 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS 1320 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS Sbjct: 1261 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS 1320 Query: 1321 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKELQ 1380 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKELQ Sbjct: 1321 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKELQ 1380 Query: 1381 GKTDNQNDPEGDQEN 1395 GKTDNQNDPEGDQEN Sbjct: 1381 GKTDNQNDPEGDQEN 1395 >gi|150378489 G protein-coupled receptor associated sorting protein 1 [Homo sapiens] Length = 1395 Score = 2846 bits (7378), Expect = 0.0 Identities = 1395/1395 (100%), Positives = 1395/1395 (100%) Query: 1 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP 60 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP Sbjct: 1 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP 60 Query: 61 GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP 120 GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP Sbjct: 61 GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP 120 Query: 121 LVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRP 180 LVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRP Sbjct: 121 LVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRP 180 Query: 181 TSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQ 240 TSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQ Sbjct: 181 TSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQ 240 Query: 241 TNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSRSRFRSKKEVYVESSSGSE 300 TNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSRSRFRSKKEVYVESSSGSE Sbjct: 241 TNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSRSRFRSKKEVYVESSSGSE 300 Query: 301 HEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPE 360 HEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPE Sbjct: 301 HEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPE 360 Query: 361 ENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADE 420 ENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADE Sbjct: 361 ENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADE 420 Query: 421 ASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTG 480 ASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTG Sbjct: 421 ASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTG 480 Query: 481 AEATSESILAADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCES 540 AEATSESILAADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCES Sbjct: 481 AEATSESILAADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCES 540 Query: 541 RTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQTYMDCRAETSC 600 RTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQTYMDCRAETSC Sbjct: 541 RTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQTYMDCRAETSC 600 Query: 601 DTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAKEEVSMKHGTGV 660 DTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAKEEVSMKHGTGV Sbjct: 601 DTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAKEEVSMKHGTGV 660 Query: 661 RCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAII 720 RCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAII Sbjct: 661 RCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAII 720 Query: 721 GSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEATDREESRPEAEEGDIIG 780 GSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEATDREESRPEAEEGDIIG Sbjct: 721 GSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEATDREESRPEAEEGDIIG 780 Query: 781 SWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREETIRREAGSCSKSSPKAEEEE 840 SWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREETIRREAGSCSKSSPKAEEEE Sbjct: 781 SWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREETIRREAGSCSKSSPKAEEEE 840 Query: 841 VIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESE 900 VIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESE Sbjct: 841 VIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESE 900 Query: 901 TEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESK 960 TEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESK Sbjct: 901 TEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESK 960 Query: 961 PENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLADEDEAIVGSWFWAGDEAHFESNPSP 1020 PENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLADEDEAIVGSWFWAGDEAHFESNPSP Sbjct: 961 PENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLADEDEAIVGSWFWAGDEAHFESNPSP 1020 Query: 1021 VFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRFPKEAASLFCE 1080 VFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRFPKEAASLFCE Sbjct: 1021 VFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRFPKEAASLFCE 1080 Query: 1081 MFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESS 1140 MFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESS Sbjct: 1081 MFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESS 1140 Query: 1141 SCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSL 1200 SCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSL Sbjct: 1141 SCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSL 1200 Query: 1201 IETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRM 1260 IETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRM Sbjct: 1201 IETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRM 1260 Query: 1261 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS 1320 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS Sbjct: 1261 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS 1320 Query: 1321 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKELQ 1380 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKELQ Sbjct: 1321 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKELQ 1380 Query: 1381 GKTDNQNDPEGDQEN 1395 GKTDNQNDPEGDQEN Sbjct: 1381 GKTDNQNDPEGDQEN 1395 >gi|103472136 G protein-coupled receptor associated sorting protein 1 [Homo sapiens] Length = 1395 Score = 2846 bits (7378), Expect = 0.0 Identities = 1395/1395 (100%), Positives = 1395/1395 (100%) Query: 1 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP 60 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP Sbjct: 1 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP 60 Query: 61 GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP 120 GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP Sbjct: 61 GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP 120 Query: 121 LVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRP 180 LVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRP Sbjct: 121 LVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRP 180 Query: 181 TSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQ 240 TSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQ Sbjct: 181 TSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQ 240 Query: 241 TNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSRSRFRSKKEVYVESSSGSE 300 TNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSRSRFRSKKEVYVESSSGSE Sbjct: 241 TNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSRSRFRSKKEVYVESSSGSE 300 Query: 301 HEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPE 360 HEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPE Sbjct: 301 HEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPE 360 Query: 361 ENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADE 420 ENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADE Sbjct: 361 ENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADE 420 Query: 421 ASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTG 480 ASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTG Sbjct: 421 ASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTG 480 Query: 481 AEATSESILAADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCES 540 AEATSESILAADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCES Sbjct: 481 AEATSESILAADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCES 540 Query: 541 RTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQTYMDCRAETSC 600 RTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQTYMDCRAETSC Sbjct: 541 RTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQTYMDCRAETSC 600 Query: 601 DTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAKEEVSMKHGTGV 660 DTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAKEEVSMKHGTGV Sbjct: 601 DTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAKEEVSMKHGTGV 660 Query: 661 RCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAII 720 RCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAII Sbjct: 661 RCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAII 720 Query: 721 GSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEATDREESRPEAEEGDIIG 780 GSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEATDREESRPEAEEGDIIG Sbjct: 721 GSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEATDREESRPEAEEGDIIG 780 Query: 781 SWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREETIRREAGSCSKSSPKAEEEE 840 SWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREETIRREAGSCSKSSPKAEEEE Sbjct: 781 SWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREETIRREAGSCSKSSPKAEEEE 840 Query: 841 VIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESE 900 VIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESE Sbjct: 841 VIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESE 900 Query: 901 TEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESK 960 TEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESK Sbjct: 901 TEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESK 960 Query: 961 PENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLADEDEAIVGSWFWAGDEAHFESNPSP 1020 PENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLADEDEAIVGSWFWAGDEAHFESNPSP Sbjct: 961 PENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLADEDEAIVGSWFWAGDEAHFESNPSP 1020 Query: 1021 VFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRFPKEAASLFCE 1080 VFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRFPKEAASLFCE Sbjct: 1021 VFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRFPKEAASLFCE 1080 Query: 1081 MFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESS 1140 MFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESS Sbjct: 1081 MFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESS 1140 Query: 1141 SCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSL 1200 SCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSL Sbjct: 1141 SCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSL 1200 Query: 1201 IETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRM 1260 IETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRM Sbjct: 1201 IETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRM 1260 Query: 1261 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS 1320 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS Sbjct: 1261 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS 1320 Query: 1321 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKELQ 1380 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKELQ Sbjct: 1321 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKELQ 1380 Query: 1381 GKTDNQNDPEGDQEN 1395 GKTDNQNDPEGDQEN Sbjct: 1381 GKTDNQNDPEGDQEN 1395 >gi|51702248 G protein-coupled receptor associated sorting protein 2 [Homo sapiens] Length = 838 Score = 631 bits (1627), Expect = e-180 Identities = 367/702 (52%), Positives = 452/702 (64%), Gaps = 69/702 (9%) Query: 700 EEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEA 759 EE + SW +SR + EA S W+ +E T + T EET + SW +E Sbjct: 200 EETNMGSWCYSRPRAREEASNESGFWSADE-----TSTASSFWTGEETSVRSWPREESNT 254 Query: 760 ISEATDREE----SRPEAEEGDIIGSWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWF 815 S + + SRP +++ + SW +G ED E W Sbjct: 255 RSRHRAKHQTNPRSRPRSKQEAYVDSW--SGSED----------------EASNPFSFWV 296 Query: 816 GAREETIRREAGSCSKSSPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITV 875 G + R P+ EE I E FES+ E+E Sbjct: 297 GENTNNLFR---------PRVREEANIRSKLRTNREDC--------FESE---SEDEFYK 336 Query: 876 GSWFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEM 935 SW P EEA+ + + E+ + + + D V +E P +EE+ Sbjct: 337 QSWVLPGEEANSRFRHRDKEDPNTALK---LRAQKDVDSDRVKQE--------PRFEEEV 385 Query: 936 IVESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLA 995 I+ SWFW+ +A E G A CES+P EEGAI GS + AE+ ++ G+ Sbjct: 386 IIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEE----KSSLGAVAREEAKP 441 Query: 996 D-EDEAIVGSWFWAGDEAHFESNPSPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKP 1054 + E+EAI GSWFW DEA F+ NP PV++ R + E E + S RPQ+W+EVTV+FKP Sbjct: 442 ESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE-ELNASSRPQTWDEVTVEFKP 500 Query: 1055 GPWGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQ 1114 G + VGF S SPF P+EA+ EM KP+N+ LSPEGE+QESLLQPDQPSPEF FQ Sbjct: 501 GLFHGVGFRSTSPFGIPEEAS----EMLEAKPKNLELSPEGEEQESLLQPDQPSPEFTFQ 556 Query: 1115 YDPSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEI 1174 YDPSYRSV+EIREHLRA+ES E ES SC+CIQCELKIGSEEFEE LLLM+KIRDPFIHEI Sbjct: 557 YDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEI 616 Query: 1175 SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQ 1234 SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMI MAPPYPNLN+I+ Sbjct: 617 SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNMIE 676 Query: 1235 TYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRF 1294 T+IC+VCEETLA+SVDS EQL+GIRM+RHLT T DYHTL+ANYMSGFLSLL T NA+T+F Sbjct: 677 TFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANARTKF 736 Query: 1295 HVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIKK-ET 1353 HVLKMLLNLSEN + K+L SA+A+S F+GLFN EETNDNIQIV+ +F+NI N IK + Sbjct: 737 HVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGKM 796 Query: 1354 VFSDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPEGDQEN 1395 DDDF++EPLISAF + E+ AK+LQ + DNQNDPE Q++ Sbjct: 797 SLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS 838 Score = 319 bits (818), Expect = 1e-86 Identities = 210/513 (40%), Positives = 273/513 (53%), Gaps = 94/513 (18%) Query: 1 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQA---------------- 44 MTGAEIE AQ KPEKK GEEV+ G E ENDVPLVVRPKVRTQA Sbjct: 1 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60 Query: 45 ------------------QIMPGARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVS 86 Q+M GARPK +++ + GA K + AVGGAR K+ AKAIP + Sbjct: 61 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA 120 Query: 87 RFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDT 146 R K+EAQ WAQ FG E +S+ E SQTN +A PL + +S V K+K LS DRELVN D Sbjct: 121 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA 180 Query: 147 ESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDK-SVSSLFWS 205 E+FP + Q G QP F EETNMGSWC RP +++EAS S F D+ S +S FW+ Sbjct: 181 ETFPGTQG--QKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWT 238 Query: 206 GDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFWA 265 G+E + + P R + + RS H A + N SR ++ QE Y+ S SGSEDE+ FW Sbjct: 239 GEETSVRSWP--REESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWV 296 Query: 266 RDKTNTWSGP--REDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRA 323 + TN P RE+ N RS+ R+ +E ES SE E + +SW + Sbjct: 297 GENTNNLFRPRVREEANIRSKLRTNREDCFESE--SEDEFYKQSW------------VLP 342 Query: 324 GKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKE 383 G+EAN+R RHR K E+ NT A+ Sbjct: 343 GEEANSRFRHRDK------------------------EDPNT-------------ALKLR 365 Query: 384 EAKTKARARAKQEARSEEEALIGTWFWATDESSMADEAS--IESSLQVEDESIIGSWFWT 441 K R KQE R EEE +IG+WFWA E+S+ AS ES E+ +I GS +W Sbjct: 366 AQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWA 425 Query: 442 EEEASMGTGASSKSRPRTDGERIGDSLFGAREK 474 EE++S+G A +++P ++ E I S F R++ Sbjct: 426 EEKSSLGAVAREEAKPESEEEAIFGSWFWDRDE 458 Score = 144 bits (364), Expect = 5e-34 Identities = 145/553 (26%), Positives = 218/553 (39%), Gaps = 104/553 (18%) Query: 86 SRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTD 145 + + AQ + + G E ++ ER + ++ P V T + A+ K T+ Sbjct: 4 AEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPK----------TE 53 Query: 146 TESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSK--QEASPNSDFKWVDKSVSSLF 203 T+S P + +A R K E + P+ ++ A P +D + V + S Sbjct: 54 TKSVPAARPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARS--- 110 Query: 204 WSGDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWF 263 + AK PG R KD EA ++S+ E + S+ +V P Sbjct: 111 ----KTDAKAIPGARPKD----------EAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLA 156 Query: 264 WARDKTNTWSGPREDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRA 323 A SG S R V E+ G++ + ++ WFG G+E S + Sbjct: 157 TAE------SGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYS 210 Query: 324 GKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKE 383 R RA+ EA + S D S FW E + S P + R+R K Sbjct: 211 --------RPRAREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRHRAKH 262 Query: 384 EAKTKARARAKQEAR------SEEEALIGTWFWATDESS------MADEASIESSLQV-- 429 + ++R R+KQEA SE+EA FW + ++ + +EA+I S L+ Sbjct: 263 QTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENTNNLFRPRVREEANIRSKLRTNR 322 Query: 430 --------EDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGA 481 EDE SW EEA+ S F R+K T Sbjct: 323 EDCFESESEDEFYKQSWVLPGEEAN--------------------SRFRHRDKEDPNTAL 362 Query: 482 EATSESILAADDEQVIIGSWFWAGEEVNQEA--EEETIFGSWFWVIDAASVESGVGVSCE 539 + ++ + +D V QE EEE I GSWFW AS+E G CE Sbjct: 363 KLRAQKDVDSD--------------RVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICE 408 Query: 540 SRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQTYMD---CRA 596 S +EE + G +W+ E+ + A EEA+P +EEE IFGSWFW ++ D C Sbjct: 409 SEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPV 468 Query: 597 ETSCDTMQGAEEE 609 D + A EE Sbjct: 469 YKVSDRFRDAAEE 481 Score = 104 bits (259), Expect = 7e-22 Identities = 128/499 (25%), Positives = 197/499 (39%), Gaps = 113/499 (22%) Query: 368 RPMIKKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSL 427 RP ++ +A A K E K+ AR K EA++ A T Sbjct: 37 RPKVRTQATTGARPKTETKSVPAARPKTEAQAMSGARPKT-------------------- 76 Query: 428 QVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKT--GAEATS 485 E + + G+ TE + G +RP+TD +G GAR KT K GA Sbjct: 77 --EVQVMGGARPKTEAQGITG------ARPKTDARAVG----GARSKTDAKAIPGARPKD 124 Query: 486 ESILAADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESG------------ 533 E+ A E G E +AE + + W + A+ ESG Sbjct: 125 EAQAWAQSE---------FGTEAVSQAEGVSQTNAVAWPL--ATAESGSVTKSKGLSMDR 173 Query: 534 --VGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQTY 591 V V E+ ++ ++ I PWF GE+ ++ G +RP A EE S FW+ ++T Sbjct: 174 ELVNVDAETFPGTQGQKGIQPWFGPGEETNM--GSWCYSRPRAREEASNESGFWSADET- 230 Query: 592 MDCRAETSCDTMQGAEEEEPIIGSW----FWTRVEACVEGDVNSKSSLEDKEEAMIPCFG 647 T+ G EE + SW TR + N +S K+EA + + Sbjct: 231 -----STASSFWTG---EETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWS 282 Query: 648 AKEE-----VSMKHGTGVRCRFMAGAEE---------TNNKSCFWAEKEPCMYPAG---- 689 E+ S G F E TN + CF +E E Y Sbjct: 283 GSEDEASNPFSFWVGENTNNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLP 342 Query: 690 ----GGSWKSRPEEE----------EDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGT 735 ++ R +E+ +D+ + + E IIGSW WA +E++++G Sbjct: 343 GEEANSRFRHRDKEDPNTALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGG 402 Query: 736 GE---KAKLLTEEETIINSWFWKEDEAISEATDREESRPEAEEGDIIGSWFWAGEEDRLE 792 +++ TEE I S +W E+++ A REE++PE+EE I GSWFW +E + Sbjct: 403 ASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFD 462 Query: 793 ----PAAETREEDRLAAEK 807 P + + R AAE+ Sbjct: 463 LNPCPVYKVSDRFRDAAEE 481 Score = 45.4 bits (106), Expect = 4e-04 Identities = 80/291 (27%), Positives = 115/291 (39%), Gaps = 47/291 (16%) Query: 802 RLAAEKEGIVGSWFGAREETIRREAGSC-SKSSPKAEEEEVIIGSWFWEEEASPEAVAGV 860 R E +GI G AR +T R G SK+ KA I ++EA A + Sbjct: 85 RPKTEAQGITG----ARPKTDARAVGGARSKTDAKA------IPGARPKDEAQAWAQSEF 134 Query: 861 GFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEE---MESE---TEEETIFGS----- 909 G E+ E T + WP A+ ++GS + M+ E + ET G+ Sbjct: 135 GTEAVSQAEGVSQT-NAVAWPL--ATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKG 191 Query: 910 ---WFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEG 966 WF G+E + G C S+P EE ES FWS D ET T ++ + E Sbjct: 192 IQPWFGPGEETN--MGSWCYSRPRAREEASNESGFWSAD----ETSTASSFWTGEETS-- 243 Query: 967 AIVGSW--FEAEDEVDNRTDNGSNCGSRTLADEDEAIVGSWFWAGDEAH------FESNP 1018 V SW E+ +R + +N SR + EA V SW + DEA N Sbjct: 244 --VRSWPREESNTRSRHRAKHQTNPRSRP-RSKQEAYVDSWSGSEDEASNPFSFWVGENT 300 Query: 1019 SPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFR 1069 + +FR R ++ + +R E +F W G + S FR Sbjct: 301 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFR 351 >gi|19923967 G protein-coupled receptor associated sorting protein 2 [Homo sapiens] Length = 838 Score = 631 bits (1627), Expect = e-180 Identities = 367/702 (52%), Positives = 452/702 (64%), Gaps = 69/702 (9%) Query: 700 EEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEA 759 EE + SW +SR + EA S W+ +E T + T EET + SW +E Sbjct: 200 EETNMGSWCYSRPRAREEASNESGFWSADE-----TSTASSFWTGEETSVRSWPREESNT 254 Query: 760 ISEATDREE----SRPEAEEGDIIGSWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWF 815 S + + SRP +++ + SW +G ED E W Sbjct: 255 RSRHRAKHQTNPRSRPRSKQEAYVDSW--SGSED----------------EASNPFSFWV 296 Query: 816 GAREETIRREAGSCSKSSPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITV 875 G + R P+ EE I E FES+ E+E Sbjct: 297 GENTNNLFR---------PRVREEANIRSKLRTNREDC--------FESE---SEDEFYK 336 Query: 876 GSWFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEM 935 SW P EEA+ + + E+ + + + D V +E P +EE+ Sbjct: 337 QSWVLPGEEANSRFRHRDKEDPNTALK---LRAQKDVDSDRVKQE--------PRFEEEV 385 Query: 936 IVESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLA 995 I+ SWFW+ +A E G A CES+P EEGAI GS + AE+ ++ G+ Sbjct: 386 IIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEE----KSSLGAVAREEAKP 441 Query: 996 D-EDEAIVGSWFWAGDEAHFESNPSPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKP 1054 + E+EAI GSWFW DEA F+ NP PV++ R + E E + S RPQ+W+EVTV+FKP Sbjct: 442 ESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE-ELNASSRPQTWDEVTVEFKP 500 Query: 1055 GPWGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQ 1114 G + VGF S SPF P+EA+ EM KP+N+ LSPEGE+QESLLQPDQPSPEF FQ Sbjct: 501 GLFHGVGFRSTSPFGIPEEAS----EMLEAKPKNLELSPEGEEQESLLQPDQPSPEFTFQ 556 Query: 1115 YDPSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEI 1174 YDPSYRSV+EIREHLRA+ES E ES SC+CIQCELKIGSEEFEE LLLM+KIRDPFIHEI Sbjct: 557 YDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEI 616 Query: 1175 SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQ 1234 SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMI MAPPYPNLN+I+ Sbjct: 617 SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNMIE 676 Query: 1235 TYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRF 1294 T+IC+VCEETLA+SVDS EQL+GIRM+RHLT T DYHTL+ANYMSGFLSLL T NA+T+F Sbjct: 677 TFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANARTKF 736 Query: 1295 HVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIKK-ET 1353 HVLKMLLNLSEN + K+L SA+A+S F+GLFN EETNDNIQIV+ +F+NI N IK + Sbjct: 737 HVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGKM 796 Query: 1354 VFSDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPEGDQEN 1395 DDDF++EPLISAF + E+ AK+LQ + DNQNDPE Q++ Sbjct: 797 SLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS 838 Score = 319 bits (818), Expect = 1e-86 Identities = 210/513 (40%), Positives = 273/513 (53%), Gaps = 94/513 (18%) Query: 1 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQA---------------- 44 MTGAEIE AQ KPEKK GEEV+ G E ENDVPLVVRPKVRTQA Sbjct: 1 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60 Query: 45 ------------------QIMPGARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVS 86 Q+M GARPK +++ + GA K + AVGGAR K+ AKAIP + Sbjct: 61 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA 120 Query: 87 RFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDT 146 R K+EAQ WAQ FG E +S+ E SQTN +A PL + +S V K+K LS DRELVN D Sbjct: 121 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA 180 Query: 147 ESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDK-SVSSLFWS 205 E+FP + Q G QP F EETNMGSWC RP +++EAS S F D+ S +S FW+ Sbjct: 181 ETFPGTQG--QKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWT 238 Query: 206 GDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFWA 265 G+E + + P R + + RS H A + N SR ++ QE Y+ S SGSEDE+ FW Sbjct: 239 GEETSVRSWP--REESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWV 296 Query: 266 RDKTNTWSGP--REDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRA 323 + TN P RE+ N RS+ R+ +E ES SE E + +SW + Sbjct: 297 GENTNNLFRPRVREEANIRSKLRTNREDCFESE--SEDEFYKQSW------------VLP 342 Query: 324 GKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKE 383 G+EAN+R RHR K E+ NT A+ Sbjct: 343 GEEANSRFRHRDK------------------------EDPNT-------------ALKLR 365 Query: 384 EAKTKARARAKQEARSEEEALIGTWFWATDESSMADEAS--IESSLQVEDESIIGSWFWT 441 K R KQE R EEE +IG+WFWA E+S+ AS ES E+ +I GS +W Sbjct: 366 AQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWA 425 Query: 442 EEEASMGTGASSKSRPRTDGERIGDSLFGAREK 474 EE++S+G A +++P ++ E I S F R++ Sbjct: 426 EEKSSLGAVAREEAKPESEEEAIFGSWFWDRDE 458 Score = 144 bits (364), Expect = 5e-34 Identities = 145/553 (26%), Positives = 218/553 (39%), Gaps = 104/553 (18%) Query: 86 SRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTD 145 + + AQ + + G E ++ ER + ++ P V T + A+ K T+ Sbjct: 4 AEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPK----------TE 53 Query: 146 TESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSK--QEASPNSDFKWVDKSVSSLF 203 T+S P + +A R K E + P+ ++ A P +D + V + S Sbjct: 54 TKSVPAARPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARS--- 110 Query: 204 WSGDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWF 263 + AK PG R KD EA ++S+ E + S+ +V P Sbjct: 111 ----KTDAKAIPGARPKD----------EAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLA 156 Query: 264 WARDKTNTWSGPREDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRA 323 A SG S R V E+ G++ + ++ WFG G+E S + Sbjct: 157 TAE------SGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYS 210 Query: 324 GKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKE 383 R RA+ EA + S D S FW E + S P + R+R K Sbjct: 211 --------RPRAREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRHRAKH 262 Query: 384 EAKTKARARAKQEAR------SEEEALIGTWFWATDESS------MADEASIESSLQV-- 429 + ++R R+KQEA SE+EA FW + ++ + +EA+I S L+ Sbjct: 263 QTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENTNNLFRPRVREEANIRSKLRTNR 322 Query: 430 --------EDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGA 481 EDE SW EEA+ S F R+K T Sbjct: 323 EDCFESESEDEFYKQSWVLPGEEAN--------------------SRFRHRDKEDPNTAL 362 Query: 482 EATSESILAADDEQVIIGSWFWAGEEVNQEA--EEETIFGSWFWVIDAASVESGVGVSCE 539 + ++ + +D V QE EEE I GSWFW AS+E G CE Sbjct: 363 KLRAQKDVDSD--------------RVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICE 408 Query: 540 SRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQTYMD---CRA 596 S +EE + G +W+ E+ + A EEA+P +EEE IFGSWFW ++ D C Sbjct: 409 SEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPV 468 Query: 597 ETSCDTMQGAEEE 609 D + A EE Sbjct: 469 YKVSDRFRDAAEE 481 Score = 104 bits (259), Expect = 7e-22 Identities = 128/499 (25%), Positives = 197/499 (39%), Gaps = 113/499 (22%) Query: 368 RPMIKKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSL 427 RP ++ +A A K E K+ AR K EA++ A T Sbjct: 37 RPKVRTQATTGARPKTETKSVPAARPKTEAQAMSGARPKT-------------------- 76 Query: 428 QVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKT--GAEATS 485 E + + G+ TE + G +RP+TD +G GAR KT K GA Sbjct: 77 --EVQVMGGARPKTEAQGITG------ARPKTDARAVG----GARSKTDAKAIPGARPKD 124 Query: 486 ESILAADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESG------------ 533 E+ A E G E +AE + + W + A+ ESG Sbjct: 125 EAQAWAQSE---------FGTEAVSQAEGVSQTNAVAWPL--ATAESGSVTKSKGLSMDR 173 Query: 534 --VGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQTY 591 V V E+ ++ ++ I PWF GE+ ++ G +RP A EE S FW+ ++T Sbjct: 174 ELVNVDAETFPGTQGQKGIQPWFGPGEETNM--GSWCYSRPRAREEASNESGFWSADET- 230 Query: 592 MDCRAETSCDTMQGAEEEEPIIGSW----FWTRVEACVEGDVNSKSSLEDKEEAMIPCFG 647 T+ G EE + SW TR + N +S K+EA + + Sbjct: 231 -----STASSFWTG---EETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWS 282 Query: 648 AKEE-----VSMKHGTGVRCRFMAGAEE---------TNNKSCFWAEKEPCMYPAG---- 689 E+ S G F E TN + CF +E E Y Sbjct: 283 GSEDEASNPFSFWVGENTNNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLP 342 Query: 690 ----GGSWKSRPEEE----------EDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGT 735 ++ R +E+ +D+ + + E IIGSW WA +E++++G Sbjct: 343 GEEANSRFRHRDKEDPNTALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGG 402 Query: 736 GE---KAKLLTEEETIINSWFWKEDEAISEATDREESRPEAEEGDIIGSWFWAGEEDRLE 792 +++ TEE I S +W E+++ A REE++PE+EE I GSWFW +E + Sbjct: 403 ASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFD 462 Query: 793 ----PAAETREEDRLAAEK 807 P + + R AAE+ Sbjct: 463 LNPCPVYKVSDRFRDAAEE 481 Score = 45.4 bits (106), Expect = 4e-04 Identities = 80/291 (27%), Positives = 115/291 (39%), Gaps = 47/291 (16%) Query: 802 RLAAEKEGIVGSWFGAREETIRREAGSC-SKSSPKAEEEEVIIGSWFWEEEASPEAVAGV 860 R E +GI G AR +T R G SK+ KA I ++EA A + Sbjct: 85 RPKTEAQGITG----ARPKTDARAVGGARSKTDAKA------IPGARPKDEAQAWAQSEF 134 Query: 861 GFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEE---MESE---TEEETIFGS----- 909 G E+ E T + WP A+ ++GS + M+ E + ET G+ Sbjct: 135 GTEAVSQAEGVSQT-NAVAWPL--ATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKG 191 Query: 910 ---WFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEG 966 WF G+E + G C S+P EE ES FWS D ET T ++ + E Sbjct: 192 IQPWFGPGEETN--MGSWCYSRPRAREEASNESGFWSAD----ETSTASSFWTGEETS-- 243 Query: 967 AIVGSW--FEAEDEVDNRTDNGSNCGSRTLADEDEAIVGSWFWAGDEAH------FESNP 1018 V SW E+ +R + +N SR + EA V SW + DEA N Sbjct: 244 --VRSWPREESNTRSRHRAKHQTNPRSRP-RSKQEAYVDSWSGSEDEASNPFSFWVGENT 300 Query: 1019 SPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFR 1069 + +FR R ++ + +R E +F W G + S FR Sbjct: 301 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFR 351 >gi|239757861 PREDICTED: similar to armadillo repeat containing, X-linked 4 [Homo sapiens] Length = 2382 Score = 257 bits (656), Expect = 6e-68 Identities = 370/1513 (24%), Positives = 606/1513 (40%), Gaps = 262/1513 (17%) Query: 17 KPGEEVVGGAEIENDVPLVVRPKV--RTQAQIMPGARPKNKSK------------VMPGA 62 K VV A D +P+V +Q + +PGAR K K +M Sbjct: 981 KGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISKAEAGAGIMGSV 1040 Query: 63 STKVETSAVGGARPKSKAK------AIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNI 116 +V S G P +K K A+P + + AQP+ A S+T ++ + Sbjct: 1041 QVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSAQPQAVANSQSETLLGARNKV 1100 Query: 117 IASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSWC 176 + + + A T++ ++ + + + E+ P + + + +++E Sbjct: 1101 KGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKSMSTSEAEATAEDEAYAKPEA 1160 Query: 177 CPRPTSKQEASPNSDF-KWVDKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMHMANQEANT 235 PTS+ E + + ++ +W+G V +K R M N+ Sbjct: 1161 EAMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVEDWIAAERWIKF--RFQTMDGDWENS 1218 Query: 236 MSRSQTNQELYIASSSGSEDES-VKTPWFWARDKTN--TWSGPREDPN------SRSRFR 286 +S + E I S SG+ D++ + W A D+T+ +W+G R + +R+ + Sbjct: 1219 VSWADDENEASIGSWSGASDKAGIIRSWAVACDETSVKSWAGARAENVVGIGTWARAGEQ 1278 Query: 287 SKKEVYV--ESSSGSEHEDHLE--SWFGAGKEAKFRSKMRAGKEANNRARHRAKREACID 342 + ++ ++S G+ D +W GA +A S AG +A + Sbjct: 1279 ASGGLWAGGQTSEGTWAGDKASGGAWTGAENQASGGSWALAGNQAIGELWAAGQAS---- 1334 Query: 343 FMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEE 402 GS WP A+ S + +EA + T +E + Sbjct: 1335 --DGS----------WPGGQASGVS--WVGEEAIGGSWTG----------------AENQ 1364 Query: 403 ALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGE 462 A G+W A + +S+ V D++ GSW T +++ G S+PR + + Sbjct: 1365 ASEGSWAGA----GAGNMSSVSYWAGVVDQAGGGSWAGTSDQSGGG------SKPRFEDQ 1414 Query: 463 RIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFWAGEEVNQEAE----EETIF 518 G+ + G +A+ S+L +D Q SW ++ + + +++ Sbjct: 1415 ASGEGSWAG-------AGGQASGGSMLGPED-QSSGRSWADTADQASGGSRLGHVDQSSG 1466 Query: 519 GSWFWVIDAASVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEET 578 G+W +D +SG G ++ EE G W +G Q G ++ G E+++ Sbjct: 1467 GAWAGTLD----QSGGGSKPRFENQTTEE---GSWAGAGGQA------GGGSKVGPEDQS 1513 Query: 579 IFGSWFWAENQTYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDK 638 SW + +Q S + G ++ GSW A V K ED+ Sbjct: 1514 SGRSWANSGDQI--------SGGFLVGIVDQANG-GSW----TGAGHPASVGPKPIFEDQ 1560 Query: 639 EEAMIPCFGAKEEVSMKHGTGVRCRFMAGA-EETNNKSCFWAEKEPCMYPAG---GGSWK 694 A+E+V G+R + + T +++ W C+ P GGSW Sbjct: 1561 VSGRGSWADAREQVVGDSRLGLRDQSSGDSWAGTGDQASGWF----CVCPGSQTNGGSWG 1616 Query: 695 ---------SRP-EEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTE 744 SRP + SW P + + W T +D G +K E Sbjct: 1617 GASGQDVGGSRPGPTNQSSAGSW------DSPGSQVSGSCW-TGAGAVDQAGGCSKPGFE 1669 Query: 745 EETIINSWFWKEDEAISEATDREE--SRPEAEEGDI-IGSWFWAGEE----DRLEPAAET 797 ++ I FW A D+ SRP +E+ IGSW AG + R PA ++ Sbjct: 1670 DQAI-GGGFWPG------AGDQTGGGSRPGSEDQSSGIGSWGVAGGQVLGGARPGPADQS 1722 Query: 798 REEDRLAAEKEGIVGSWFGAREETIRREAGSCSKSSPKAEEEEVIIGSWFWE-EEASPEA 856 + SW G ++ + CSK P+ E++ GSW +AS E+ Sbjct: 1723 SGGSWAGTGNQSSGRSWIGPGDQAV-----DCSK--PEFEDQACGGGSWAGAGSQASGES 1775 Query: 857 VAGVGFESKPGTE---------EEEITVGSWFWPEEEAS----IQAGSQAVEEMESETEE 903 AG S+PG E E++ T GSW E++AS + +A E Sbjct: 1776 WAG----SRPGNEAIGGSRMGSEDQATGGSWARSEDQASGRFQVSFEVEANEGFWFGPGA 1831 Query: 904 ETIFGSWFW-----------DGKE---------VSEEAGPCCVSKPEDDEEMIVESWFWS 943 E + GSW W D K+ EEA C S+ E + + SW S Sbjct: 1832 EAVIGSWCWTEEKADIVSRPDDKDEATTASRSRAGEEAMIC--SRIEAENKASSGSWIRS 1889 Query: 944 RDKAIK------------------ETGTVATCESK----------PENEEGAIVGSWFEA 975 + A E G A E+ P E GA V SW Sbjct: 1890 EEVAYMGSCVGAEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGTESGAGVWSWDGD 1949 Query: 976 EDEVDNRTDNGSNCG--SRTLA--------------DEDEAIVGSWFWAGDEAHFESNPS 1019 V++R G G S TLA D +E + S FWA ES S Sbjct: 1950 ATTVESRLGAGEEAGVESWTLARNVGEDELSRESSPDIEEISLRSLFWA------ESENS 2003 Query: 1020 PVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRF-PKEAASLF 1078 FR+ S E + + E G W G + S + PK A Sbjct: 2004 NTFRSKSGKDASFESGAGDNTSIKDKFEAAGGVDIGSWFCAGNENTSEDKSAPKAKAKKS 2063 Query: 1079 CEMFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPE 1138 E G P + + G +++ + +F Q + S+ E R+ R E T P Sbjct: 2064 SESRGIYPYMVPGAGMGSWDGAMIWSET---KFAHQSEASFPVEDESRKQTRTGEKTRPW 2120 Query: 1139 SSSCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVV 1198 S C + E + + E+L+ ++E DP +HEI+ A+ + ++ + +R+ G + Sbjct: 2121 SCRC---KHEANMDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGI 2177 Query: 1199 SLIETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGI 1258 S+IE+LLN P VR L + ++ N ++TY+ +VCE+T+ Y ++S QL+G+ Sbjct: 2178 SVIESLLNNPYPSVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGL 2237 Query: 1259 RMIRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEA 1318 R+IRHLT T++Y +V NY+S FL LL G+ +T+ HVL MLLN S+N MTK+LL A A Sbjct: 2238 RLIRHLTITSEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANA 2297 Query: 1319 VSEFIGLFNREETNDNIQIVLAIFENIGNNIKKET-VFSDDDFNIEPLISAFHKVEKFAK 1377 + I +F+++ET +NI L++FENI + K+ F+ D F+ L F + + AK Sbjct: 2298 PTSLINIFSKKETKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAK 2357 Query: 1378 ELQGKTDNQNDPE 1390 +L+ NDPE Sbjct: 2358 KLRALAAECNDPE 2370 Score = 78.2 bits (191), Expect = 5e-14 Identities = 216/1020 (21%), Positives = 372/1020 (36%), Gaps = 210/1020 (20%) Query: 38 PKVRTQAQIMPGARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQ 97 P V +A++ GA + ++M AS+K E + K + A+ + + Q Sbjct: 744 PNVVLKAEVGEGAMGTAQLQIM--ASSKGEALLDSKNKVKGNSNAVSKAGAGTDTTGSVQ 801 Query: 98 PRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQ 157 P+ A + ++ I +P +S + T + + + N+ E P K + Sbjct: 802 PQIVANSQGEVLPGAKNKIRGNPTTVPNSGVGPYTTDSARPQAVANSQGEVLPGAKNKVK 861 Query: 158 AGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHPGN 217 A SK E MG+ +P +A NS + + + + + + + V+ K G Sbjct: 862 ANLNAV--SKAEAGMGATGSVQP----QAVANSHCETLPGAKNKVRGNWNAVS-KAGAGM 914 Query: 218 RVKDSNRSMHMANQEANTM--SRSQTNQELYIASSSGSEDESVKT--PWFWARDKTNTWS 273 + S + +AN + + ++++ + S +G+ +++V + P A + T Sbjct: 915 DTRGSAQPQAVANSQGEVLPGAKNKVKGNPNVVSKAGAREDTVGSTQPQVLASSQRETLP 974 Query: 274 GPREDPNSRSRFRSKKEVYVESSSGSEHE----DHLESWFGAGKEAKFRSKMRAGKEANN 329 G R S SK ++ ++ + E+ GA + K S + EA Sbjct: 975 GARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISKAEAGA 1034 Query: 330 RARHRAKREACIDF----MPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKEEA 385 + + F +PG+ + ++ S P+ A A Sbjct: 1035 GIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAG--------------------A 1074 Query: 386 KTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEA 445 T A+ + A S+ E L+G + +V+ +I +A Sbjct: 1075 DTVGSAQPQAVANSQSETLLG------------------ARNKVKGNTI------AVPKA 1110 Query: 446 SMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFWAG 505 G G ++P+ G++L GAR+K+ + AEAT+E Sbjct: 1111 GTGAGTRHSAQPQIVAGSQGETLPGARDKSMSTSEAEATAE------------------- 1151 Query: 506 EEVNQEAEEETIFGSWFWVIDAASVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAG 565 +E + E E + + E G G +T+ I ++W+G + +E Sbjct: 1152 DEAYAKPEAE--------AMPTSESEGGSGTQACRKTQPN----IHDYYWNG--IGVEDW 1197 Query: 566 IGEEARPGAEEETIFGSWFWAENQTYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACV 625 I E +T+ G W + ++ D E S + GA ++ II SW AC Sbjct: 1198 IAAERWIKFRFQTMDGD--WENSVSWADDENEASIGSWSGASDKAGIIRSW----AVACD 1251 Query: 626 EGDVNSKSSLEDKEEAMIPCFGAKEEVSMKHGTGVRC------RFMAGAEETNNKSCFWA 679 E V S + GA+ E + GT R AG + + WA Sbjct: 1252 ETSVKSWA-------------GARAENVVGIGTWARAGEQASGGLWAGGQTSEGT---WA 1295 Query: 680 EKEPCMYPAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGT--GE 737 + A GG+W E + SW + E LWA +++ DG+ G Sbjct: 1296 GDK-----ASGGAWTG--AENQASGGSWALAGNQAIGE------LWAAGQAS-DGSWPGG 1341 Query: 738 KAKLLT--EEETIINSWFWKEDEAI------SEATDREESRPEAEEGDIIGSWFWAGEED 789 +A ++ EE I SW E++A + A + A D G WAG D Sbjct: 1342 QASGVSWVGEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQAGGGSWAGTSD 1401 Query: 790 RLEPAAETREEDRLAAEKEGIVGSWFGAREETIRREAGSCSKSSPKAEEEEVIIGSWFWE 849 + ++ R ED+ + E GSW GA G S S E++ SW Sbjct: 1402 QSGGGSKPRFEDQASGE-----GSWAGA--------GGQASGGSMLGPEDQSSGRSW--- 1445 Query: 850 EEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGS 909 + + +A G S+ G ++ + G+W + Q+G + E++T EE GS Sbjct: 1446 ADTADQASGG----SRLG-HVDQSSGGAWAGTLD----QSGGGSKPRFENQTTEE---GS 1493 Query: 910 WFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDK----------------AIKETGT 953 W G +AG PED SW S D+ + G Sbjct: 1494 WAGAG----GQAGGGSKVGPEDQSS--GRSWANSGDQISGGFLVGIVDQANGGSWTGAGH 1547 Query: 954 VATCESKPENEEGAI-VGSWFEAEDEVDNRTDNGSNCGSRTLADEDEAIVGSWFWAGDEA 1012 A+ KP E+ GSW +A ++V G L D++ SW GD+A Sbjct: 1548 PASVGPKPIFEDQVSGRGSWADAREQV---------VGDSRLGLRDQSSGDSWAGTGDQA 1598 Score = 66.6 bits (161), Expect = 2e-10 Identities = 124/580 (21%), Positives = 227/580 (39%), Gaps = 111/580 (19%) Query: 4 AEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMPGAS 63 AEI++ QV+ + G GAE+E + + +QA+ M GA P+ +S+ A Sbjct: 155 AEIKTKPQVEIGAETGARSGPGAEVETKATAIAIHRANSQAKAMVGAEPETQSESKVVAG 214 Query: 64 TKVETSAVGGARPKSKAKAIPVSR------------------FKEEAQMWA-QPRFGAER 104 T V T AV K+KA+ + + + +A+ WA + A+R Sbjct: 215 TLVMTEAVTLTEVKAKAREVAMKEAVTQTDAEAGKIVKKEAVTQTKAKAWALVAKTEAKR 274 Query: 105 LSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGF--QP 162 + T+ ++T+I+A + V+V +++ L+ RE+ + A + G + Sbjct: 275 EAMTQTKAETHILAEKETEINRVMVTQSETLAVPREVA--------KMGATNKTGIVDET 326 Query: 163 SFRSKEET----NMGSWCCPRPTSKQEASPNS--------DFKWVDKSVSSLFWSGDEVT 210 R+ EET S P T +PN D K +S + GD++ Sbjct: 327 KTRALEETVSVAKTQSEARPGATVDARGNPNGMSREVAGVDMKSCAQSQAVTKIQGDDM- 385 Query: 211 AKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIAS--------------------- 249 PG V+D M+ E+ +R+ +++ + Sbjct: 386 ----PGTGVEDMGNCKTMSRAESGADTRASAQPQIFAKTQTEAIPGAKIDAGGNTNAMCK 441 Query: 250 -SSGSEDESVKTPWFWARDKTNTWSGPREDPNSRSRFRSKKEVYVESSSGSEHEDHLESW 308 +G++ + P A+ + SG R D + SK + + ++ + + Sbjct: 442 VGAGADVRACIQPQTVAKKQAEVTSGARVDGRGNTNVISKAITGADMRAAAQPQAVASTH 501 Query: 309 FGAGKEAKFRSK------MRAGKEANNRARHRAKR-EACIDFMPGSIDVIKKE------- 354 A +AK +++ +AG +AN RA + + D G+ +V+ K Sbjct: 502 AEAMSDAKVKNRGNPNAMTKAGAKANLRANSQVEALPDARDKSRGNPNVMAKVGDGTDML 561 Query: 355 SCFWPE----ENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFW 410 SC P+ A+T S IK M KE A +A+ A+S+ EAL T Sbjct: 562 SCTQPQLVASVQADTLSDGKIKVRGNVNTMPKEGAGVDMKAQGM--AQSQGEALPNTRGK 619 Query: 411 ATDES----------SMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTD 460 A ++ M ++ ++ E+++ S + + A +K+ R Sbjct: 620 ARGKAKAKCKTGPGMDMKTCTQPQAGVKTPAEALLDSRVDGRGNPNATSKAGTKADQRVC 679 Query: 461 GERI------GDSLFGAREK------TSMKTGA-EATSES 487 G+ + G++L GA+ K T +K GA E T++S Sbjct: 680 GQPLVVANPQGEALPGAKNKVKGNPHTVLKVGAGEGTTDS 719 >gi|216547715 basic helix-loop-helix domain containing, class B, 9 [Homo sapiens] Length = 547 Score = 236 bits (601), Expect = 1e-61 Identities = 176/599 (29%), Positives = 299/599 (49%), Gaps = 67/599 (11%) Query: 795 AETREEDRLAA--EKEGIVGSWFGAREET---IRREAGSCSKSSPKAEEEEVIIGSWFWE 849 A T+ + R A EK+ + + GA E +R A + +K+ K + + Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVA----- 56 Query: 850 EEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGS 909 E + V E+K G E T+G + + +AG+ E S + E + Sbjct: 57 -EMKAVSKNKVVAETKEGALSEPKTLGKAMG---DFTPKAGN---ESTSSTCKNEAGTDA 109 Query: 910 WFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEGAIV 969 WFW G EE + SWFW+ ++A + +T KPE + Sbjct: 110 WFWAG------------------EEATINSWFWNGEEA---GNSFSTKNDKPE------I 142 Query: 970 GSWFEAEDEVDNRTDNGSNCGSRTLADEDEA--IVGSWFWAGDEAHFESNPSPVFRAICR 1027 G+ AE+ G++C R+ A+E+E ++G+WFW GD+ F+ NP PV R + Sbjct: 143 GAQVCAEEL---EPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP 199 Query: 1028 STCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRF--PKEAASLFCEMFGGK 1085 E + RP+ W EVT+ P P++ FR P EA+ + Sbjct: 200 QPV---YEINEKNRPKDWSEVTIW----PNAPAVTPAVLGFRSQAPSEASPPSYIVLASA 252 Query: 1086 PRNMVLSPEG---EDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESSSC 1142 N P + QP PE F DP +++ EIR +R +E + +C Sbjct: 253 EENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIRIREVNGIKPFAC 312 Query: 1143 NCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIE 1202 C + E + SEEFE+L+ L++ DP IH+I++IAMG+ + F ++FI + GVV+LIE Sbjct: 313 PC-KMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTLIE 371 Query: 1203 TLLNYPSSRVRTSFLENMIRMAPPYPN--LNIIQTYICKVCEETLAYSVDSPEQLSGIRM 1260 +LL++PS +R + +I + PP + I+ ++ +C+ET+++ ++SP Q SG+++ Sbjct: 372 SLLSFPSPEMRK---KTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSPGQQSGLKI 428 Query: 1261 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS 1320 + LTT +H +VANY S LL++GN KTR VLK+LLN+SEN +++++ +A++ Sbjct: 429 LGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARDMINMKALA 488 Query: 1321 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKEL 1379 +FN++E N+ +AIF NI +I+K ++ D + L++ F +V++ + + Sbjct: 489 ALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREVKEIIETM 547 Score = 67.0 bits (162), Expect = 1e-10 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 17/196 (8%) Query: 372 KKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVED 431 K + RA+A T+++A +A+A A++EA + T A ++ +A E V Sbjct: 5 KNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA-VSK 63 Query: 432 ESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGA-REKTSMKTGAEATSESILA 490 ++ T + S P+T G+ +GD A E TS EA +++ Sbjct: 64 NKVVAE-----------TKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFW 112 Query: 491 ADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCESRTRSEEEE-- 548 A +E I SWFW GEE + + A +E G C+ R+ +EEEE Sbjct: 113 AGEEATI-NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEE 171 Query: 549 -VIGPWFWSGEQVDIE 563 VIG WFW G+ + Sbjct: 172 NVIGNWFWEGDDTSFD 187 Score = 63.2 bits (152), Expect = 2e-09 Identities = 57/204 (27%), Positives = 93/204 (45%), Gaps = 37/204 (18%) Query: 323 AGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMT- 381 AG + RA+ + +++A I G+ E A RP+ K A+A+A T Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGA------------EREATGVVRPVAKTRAKAKAKTG 49 Query: 382 ---------KEEAKTKARARAKQEARSEEEAL---IGTWF-WATDESSMA---DEASIES 425 K +K K A K+ A SE + L +G + A +ES+ + +EA ++ Sbjct: 50 SKTDAVAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDA 109 Query: 426 SLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATS 485 +E+ I SWFW EEA G S+K+ D IG + E+ GA+ Sbjct: 110 WFWAGEEATINSWFWNGEEA--GNSFSTKN----DKPEIGAQV--CAEELEPAAGADCKP 161 Query: 486 ESILAADDEQVIIGSWFWAGEEVN 509 S ++E+ +IG+WFW G++ + Sbjct: 162 RSGAEEEEEENVIGNWFWEGDDTS 185 Score = 49.7 bits (117), Expect = 2e-05 Identities = 59/232 (25%), Positives = 93/232 (40%), Gaps = 40/232 (17%) Query: 228 MANQEANTMSRSQTNQELYIASSSGSEDES--VKTPWFWARDKTNTWSGPREDPNSRSRF 285 MA + T ++++T ++ I + +G+E E+ V P R K +G + D + + Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60 Query: 286 RSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMP 345 SK +V E+ G+ E GK A +AG E+ + K EA D Sbjct: 61 VSKNKVVAETKEGALSEPKT-----LGK-AMGDFTPKAGNESTSST---CKNEAGTDAWF 111 Query: 346 GSIDVIKKESCFWP-EENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEAL 404 + + S FW EE N+FS K E A+ EE + A A K + +EEE Sbjct: 112 WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCA-EELEPAAGADCKPRSGAEEE-- 168 Query: 405 IGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSR 456 E+E++IG+WFW ++ S SR Sbjct: 169 -------------------------EEENVIGNWFWEGDDTSFDPNPKPVSR 195 Score = 46.2 bits (108), Expect = 2e-04 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 10/108 (9%) Query: 687 PAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEE 746 P G S + E ++WFW+ + EA I SW W EE+ G ++ Sbjct: 90 PKAGNESTSSTCKNEAGTDAWFWAGE----EATINSWFWNGEEA-----GNSFSTKNDKP 140 Query: 747 TIINSWFWKEDEAISEATDREESRPEAEEGD-IIGSWFWAGEEDRLEP 793 I +E E + A + S E EE + +IG+WFW G++ +P Sbjct: 141 EIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDP 188 Score = 42.0 bits (97), Expect = 0.004 Identities = 57/251 (22%), Positives = 96/251 (38%), Gaps = 57/251 (22%) Query: 50 ARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTE 109 A KNK++ K A GA ++ PV++ + +A K + Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKA--------------KAK 47 Query: 110 RNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEE 169 S+T+ +A + V+K K ++E +E S P+ F P ++ Sbjct: 48 TGSKTDAVA------EMKAVSKNKVVAETKE----GALSEPKTLGKAMGDFTPKAGNEST 97 Query: 170 TNMGSWCCPRPTSKQEASPNSDFKWV--DKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMH 227 ++ T K EA ++ F W + +++S FW+G+E F N + + Sbjct: 98 SS---------TCKNEAGTDAWF-WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVC 147 Query: 228 MANQE----ANTMSRSQTNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSR- 282 E A+ RS +E E+E+V WFW D T+ DPN + Sbjct: 148 AEELEPAAGADCKPRSGAEEE---------EEENVIGNWFWEGDDTSF------DPNPKP 192 Query: 283 -SRFRSKKEVY 292 SR + VY Sbjct: 193 VSRIVKPQPVY 203 Score = 42.0 bits (97), Expect = 0.004 Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 16/99 (16%) Query: 684 CMYPAGGGSWKSRPEEEEDIVNSWFW---------SRKYTKPEAIIGSWLWATEESNIDG 734 C AG +W EE +NSWFW S K KPE IG+ + A E G Sbjct: 101 CKNEAGTDAWFWAGEEAT--INSWFWNGEEAGNSFSTKNDKPE--IGAQVCAEELEPAAG 156 Query: 735 TGEKAKLLTEEE---TIINSWFWKEDEAISEATDREESR 770 K + EEE +I +WFW+ D+ + + SR Sbjct: 157 ADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSR 195 Score = 38.5 bits (88), Expect = 0.046 Identities = 36/120 (30%), Positives = 46/120 (38%), Gaps = 37/120 (30%) Query: 590 TYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAK 649 T C+ E D A EE I SWFW EA NS S+ DK E I Sbjct: 97 TSSTCKNEAGTDAWFWAGEEATI-NSWFWNGEEA-----GNSFSTKNDKPE--IGAQVCA 148 Query: 650 EEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFW 709 EE ++ G C+ +GAEE EEEE+++ +WFW Sbjct: 149 EE--LEPAAGADCKPRSGAEE---------------------------EEEENVIGNWFW 179 Score = 37.4 bits (85), Expect = 0.10 Identities = 56/220 (25%), Positives = 81/220 (36%), Gaps = 35/220 (15%) Query: 1 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP 60 M G + ++ AQ K EKK + GA E + VVRP +T+A+ A+ K SK Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGA--EREATGVVRPVAKTRAK----AKAKTGSKTDA 54 Query: 61 GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP 120 A K + A K A + P + K P+ G E S T +N Sbjct: 55 VAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDF--TPKAGNESTSSTCKNE-------- 104 Query: 121 LVSTDSVLVAK-----TKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSW 175 TD+ A + E N SF + + G Q E G+ Sbjct: 105 -AGTDAWFWAGEEATINSWFWNGEEAGN----SFSTKNDKPEIGAQVCAEELEPA-AGAD 158 Query: 176 CCPRPTSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHP 215 C PR +++E N W FW GD+ + +P Sbjct: 159 CKPRSGAEEEEEENVIGNW--------FWEGDDTSFDPNP 190 >gi|216547682 basic helix-loop-helix domain containing, class B, 9 [Homo sapiens] Length = 547 Score = 236 bits (601), Expect = 1e-61 Identities = 176/599 (29%), Positives = 299/599 (49%), Gaps = 67/599 (11%) Query: 795 AETREEDRLAA--EKEGIVGSWFGAREET---IRREAGSCSKSSPKAEEEEVIIGSWFWE 849 A T+ + R A EK+ + + GA E +R A + +K+ K + + Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVA----- 56 Query: 850 EEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGS 909 E + V E+K G E T+G + + +AG+ E S + E + Sbjct: 57 -EMKAVSKNKVVAETKEGALSEPKTLGKAMG---DFTPKAGN---ESTSSTCKNEAGTDA 109 Query: 910 WFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEGAIV 969 WFW G EE + SWFW+ ++A + +T KPE + Sbjct: 110 WFWAG------------------EEATINSWFWNGEEA---GNSFSTKNDKPE------I 142 Query: 970 GSWFEAEDEVDNRTDNGSNCGSRTLADEDEA--IVGSWFWAGDEAHFESNPSPVFRAICR 1027 G+ AE+ G++C R+ A+E+E ++G+WFW GD+ F+ NP PV R + Sbjct: 143 GAQVCAEEL---EPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP 199 Query: 1028 STCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRF--PKEAASLFCEMFGGK 1085 E + RP+ W EVT+ P P++ FR P EA+ + Sbjct: 200 QPV---YEINEKNRPKDWSEVTIW----PNAPAVTPAVLGFRSQAPSEASPPSYIVLASA 252 Query: 1086 PRNMVLSPEG---EDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESSSC 1142 N P + QP PE F DP +++ EIR +R +E + +C Sbjct: 253 EENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIRIREVNGIKPFAC 312 Query: 1143 NCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIE 1202 C + E + SEEFE+L+ L++ DP IH+I++IAMG+ + F ++FI + GVV+LIE Sbjct: 313 PC-KMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTLIE 371 Query: 1203 TLLNYPSSRVRTSFLENMIRMAPPYPN--LNIIQTYICKVCEETLAYSVDSPEQLSGIRM 1260 +LL++PS +R + +I + PP + I+ ++ +C+ET+++ ++SP Q SG+++ Sbjct: 372 SLLSFPSPEMRK---KTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSPGQQSGLKI 428 Query: 1261 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS 1320 + LTT +H +VANY S LL++GN KTR VLK+LLN+SEN +++++ +A++ Sbjct: 429 LGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARDMINMKALA 488 Query: 1321 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKEL 1379 +FN++E N+ +AIF NI +I+K ++ D + L++ F +V++ + + Sbjct: 489 ALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREVKEIIETM 547 Score = 67.0 bits (162), Expect = 1e-10 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 17/196 (8%) Query: 372 KKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVED 431 K + RA+A T+++A +A+A A++EA + T A ++ +A E V Sbjct: 5 KNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA-VSK 63 Query: 432 ESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGA-REKTSMKTGAEATSESILA 490 ++ T + S P+T G+ +GD A E TS EA +++ Sbjct: 64 NKVVAE-----------TKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFW 112 Query: 491 ADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCESRTRSEEEE-- 548 A +E I SWFW GEE + + A +E G C+ R+ +EEEE Sbjct: 113 AGEEATI-NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEE 171 Query: 549 -VIGPWFWSGEQVDIE 563 VIG WFW G+ + Sbjct: 172 NVIGNWFWEGDDTSFD 187 Score = 63.2 bits (152), Expect = 2e-09 Identities = 57/204 (27%), Positives = 93/204 (45%), Gaps = 37/204 (18%) Query: 323 AGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMT- 381 AG + RA+ + +++A I G+ E A RP+ K A+A+A T Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGA------------EREATGVVRPVAKTRAKAKAKTG 49 Query: 382 ---------KEEAKTKARARAKQEARSEEEAL---IGTWF-WATDESSMA---DEASIES 425 K +K K A K+ A SE + L +G + A +ES+ + +EA ++ Sbjct: 50 SKTDAVAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDA 109 Query: 426 SLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATS 485 +E+ I SWFW EEA G S+K+ D IG + E+ GA+ Sbjct: 110 WFWAGEEATINSWFWNGEEA--GNSFSTKN----DKPEIGAQV--CAEELEPAAGADCKP 161 Query: 486 ESILAADDEQVIIGSWFWAGEEVN 509 S ++E+ +IG+WFW G++ + Sbjct: 162 RSGAEEEEEENVIGNWFWEGDDTS 185 Score = 49.7 bits (117), Expect = 2e-05 Identities = 59/232 (25%), Positives = 93/232 (40%), Gaps = 40/232 (17%) Query: 228 MANQEANTMSRSQTNQELYIASSSGSEDES--VKTPWFWARDKTNTWSGPREDPNSRSRF 285 MA + T ++++T ++ I + +G+E E+ V P R K +G + D + + Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60 Query: 286 RSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMP 345 SK +V E+ G+ E GK A +AG E+ + K EA D Sbjct: 61 VSKNKVVAETKEGALSEPKT-----LGK-AMGDFTPKAGNESTSST---CKNEAGTDAWF 111 Query: 346 GSIDVIKKESCFWP-EENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEAL 404 + + S FW EE N+FS K E A+ EE + A A K + +EEE Sbjct: 112 WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCA-EELEPAAGADCKPRSGAEEE-- 168 Query: 405 IGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSR 456 E+E++IG+WFW ++ S SR Sbjct: 169 -------------------------EEENVIGNWFWEGDDTSFDPNPKPVSR 195 Score = 46.2 bits (108), Expect = 2e-04 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 10/108 (9%) Query: 687 PAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEE 746 P G S + E ++WFW+ + EA I SW W EE+ G ++ Sbjct: 90 PKAGNESTSSTCKNEAGTDAWFWAGE----EATINSWFWNGEEA-----GNSFSTKNDKP 140 Query: 747 TIINSWFWKEDEAISEATDREESRPEAEEGD-IIGSWFWAGEEDRLEP 793 I +E E + A + S E EE + +IG+WFW G++ +P Sbjct: 141 EIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDP 188 Score = 42.0 bits (97), Expect = 0.004 Identities = 57/251 (22%), Positives = 96/251 (38%), Gaps = 57/251 (22%) Query: 50 ARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTE 109 A KNK++ K A GA ++ PV++ + +A K + Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKA--------------KAK 47 Query: 110 RNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEE 169 S+T+ +A + V+K K ++E +E S P+ F P ++ Sbjct: 48 TGSKTDAVA------EMKAVSKNKVVAETKE----GALSEPKTLGKAMGDFTPKAGNEST 97 Query: 170 TNMGSWCCPRPTSKQEASPNSDFKWV--DKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMH 227 ++ T K EA ++ F W + +++S FW+G+E F N + + Sbjct: 98 SS---------TCKNEAGTDAWF-WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVC 147 Query: 228 MANQE----ANTMSRSQTNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSR- 282 E A+ RS +E E+E+V WFW D T+ DPN + Sbjct: 148 AEELEPAAGADCKPRSGAEEE---------EEENVIGNWFWEGDDTSF------DPNPKP 192 Query: 283 -SRFRSKKEVY 292 SR + VY Sbjct: 193 VSRIVKPQPVY 203 Score = 42.0 bits (97), Expect = 0.004 Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 16/99 (16%) Query: 684 CMYPAGGGSWKSRPEEEEDIVNSWFW---------SRKYTKPEAIIGSWLWATEESNIDG 734 C AG +W EE +NSWFW S K KPE IG+ + A E G Sbjct: 101 CKNEAGTDAWFWAGEEAT--INSWFWNGEEAGNSFSTKNDKPE--IGAQVCAEELEPAAG 156 Query: 735 TGEKAKLLTEEE---TIINSWFWKEDEAISEATDREESR 770 K + EEE +I +WFW+ D+ + + SR Sbjct: 157 ADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSR 195 Score = 38.5 bits (88), Expect = 0.046 Identities = 36/120 (30%), Positives = 46/120 (38%), Gaps = 37/120 (30%) Query: 590 TYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAK 649 T C+ E D A EE I SWFW EA NS S+ DK E I Sbjct: 97 TSSTCKNEAGTDAWFWAGEEATI-NSWFWNGEEA-----GNSFSTKNDKPE--IGAQVCA 148 Query: 650 EEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFW 709 EE ++ G C+ +GAEE EEEE+++ +WFW Sbjct: 149 EE--LEPAAGADCKPRSGAEE---------------------------EEEENVIGNWFW 179 Score = 37.4 bits (85), Expect = 0.10 Identities = 56/220 (25%), Positives = 81/220 (36%), Gaps = 35/220 (15%) Query: 1 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP 60 M G + ++ AQ K EKK + GA E + VVRP +T+A+ A+ K SK Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGA--EREATGVVRPVAKTRAK----AKAKTGSKTDA 54 Query: 61 GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP 120 A K + A K A + P + K P+ G E S T +N Sbjct: 55 VAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDF--TPKAGNESTSSTCKNE-------- 104 Query: 121 LVSTDSVLVAK-----TKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSW 175 TD+ A + E N SF + + G Q E G+ Sbjct: 105 -AGTDAWFWAGEEATINSWFWNGEEAGN----SFSTKNDKPEIGAQVCAEELEPA-AGAD 158 Query: 176 CCPRPTSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHP 215 C PR +++E N W FW GD+ + +P Sbjct: 159 CKPRSGAEEEEEENVIGNW--------FWEGDDTSFDPNP 190 >gi|216547672 basic helix-loop-helix domain containing, class B, 9 [Homo sapiens] Length = 547 Score = 236 bits (601), Expect = 1e-61 Identities = 176/599 (29%), Positives = 299/599 (49%), Gaps = 67/599 (11%) Query: 795 AETREEDRLAA--EKEGIVGSWFGAREET---IRREAGSCSKSSPKAEEEEVIIGSWFWE 849 A T+ + R A EK+ + + GA E +R A + +K+ K + + Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVA----- 56 Query: 850 EEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGS 909 E + V E+K G E T+G + + +AG+ E S + E + Sbjct: 57 -EMKAVSKNKVVAETKEGALSEPKTLGKAMG---DFTPKAGN---ESTSSTCKNEAGTDA 109 Query: 910 WFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEGAIV 969 WFW G EE + SWFW+ ++A + +T KPE + Sbjct: 110 WFWAG------------------EEATINSWFWNGEEA---GNSFSTKNDKPE------I 142 Query: 970 GSWFEAEDEVDNRTDNGSNCGSRTLADEDEA--IVGSWFWAGDEAHFESNPSPVFRAICR 1027 G+ AE+ G++C R+ A+E+E ++G+WFW GD+ F+ NP PV R + Sbjct: 143 GAQVCAEEL---EPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP 199 Query: 1028 STCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRF--PKEAASLFCEMFGGK 1085 E + RP+ W EVT+ P P++ FR P EA+ + Sbjct: 200 QPV---YEINEKNRPKDWSEVTIW----PNAPAVTPAVLGFRSQAPSEASPPSYIVLASA 252 Query: 1086 PRNMVLSPEG---EDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESSSC 1142 N P + QP PE F DP +++ EIR +R +E + +C Sbjct: 253 EENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIRIREVNGIKPFAC 312 Query: 1143 NCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIE 1202 C + E + SEEFE+L+ L++ DP IH+I++IAMG+ + F ++FI + GVV+LIE Sbjct: 313 PC-KMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTLIE 371 Query: 1203 TLLNYPSSRVRTSFLENMIRMAPPYPN--LNIIQTYICKVCEETLAYSVDSPEQLSGIRM 1260 +LL++PS +R + +I + PP + I+ ++ +C+ET+++ ++SP Q SG+++ Sbjct: 372 SLLSFPSPEMRK---KTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSPGQQSGLKI 428 Query: 1261 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS 1320 + LTT +H +VANY S LL++GN KTR VLK+LLN+SEN +++++ +A++ Sbjct: 429 LGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARDMINMKALA 488 Query: 1321 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKEL 1379 +FN++E N+ +AIF NI +I+K ++ D + L++ F +V++ + + Sbjct: 489 ALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREVKEIIETM 547 Score = 67.0 bits (162), Expect = 1e-10 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 17/196 (8%) Query: 372 KKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVED 431 K + RA+A T+++A +A+A A++EA + T A ++ +A E V Sbjct: 5 KNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA-VSK 63 Query: 432 ESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGA-REKTSMKTGAEATSESILA 490 ++ T + S P+T G+ +GD A E TS EA +++ Sbjct: 64 NKVVAE-----------TKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFW 112 Query: 491 ADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCESRTRSEEEE-- 548 A +E I SWFW GEE + + A +E G C+ R+ +EEEE Sbjct: 113 AGEEATI-NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEE 171 Query: 549 -VIGPWFWSGEQVDIE 563 VIG WFW G+ + Sbjct: 172 NVIGNWFWEGDDTSFD 187 Score = 63.2 bits (152), Expect = 2e-09 Identities = 57/204 (27%), Positives = 93/204 (45%), Gaps = 37/204 (18%) Query: 323 AGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMT- 381 AG + RA+ + +++A I G+ E A RP+ K A+A+A T Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGA------------EREATGVVRPVAKTRAKAKAKTG 49 Query: 382 ---------KEEAKTKARARAKQEARSEEEAL---IGTWF-WATDESSMA---DEASIES 425 K +K K A K+ A SE + L +G + A +ES+ + +EA ++ Sbjct: 50 SKTDAVAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDA 109 Query: 426 SLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATS 485 +E+ I SWFW EEA G S+K+ D IG + E+ GA+ Sbjct: 110 WFWAGEEATINSWFWNGEEA--GNSFSTKN----DKPEIGAQV--CAEELEPAAGADCKP 161 Query: 486 ESILAADDEQVIIGSWFWAGEEVN 509 S ++E+ +IG+WFW G++ + Sbjct: 162 RSGAEEEEEENVIGNWFWEGDDTS 185 Score = 49.7 bits (117), Expect = 2e-05 Identities = 59/232 (25%), Positives = 93/232 (40%), Gaps = 40/232 (17%) Query: 228 MANQEANTMSRSQTNQELYIASSSGSEDES--VKTPWFWARDKTNTWSGPREDPNSRSRF 285 MA + T ++++T ++ I + +G+E E+ V P R K +G + D + + Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60 Query: 286 RSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMP 345 SK +V E+ G+ E GK A +AG E+ + K EA D Sbjct: 61 VSKNKVVAETKEGALSEPKT-----LGK-AMGDFTPKAGNESTSST---CKNEAGTDAWF 111 Query: 346 GSIDVIKKESCFWP-EENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEAL 404 + + S FW EE N+FS K E A+ EE + A A K + +EEE Sbjct: 112 WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCA-EELEPAAGADCKPRSGAEEE-- 168 Query: 405 IGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSR 456 E+E++IG+WFW ++ S SR Sbjct: 169 -------------------------EEENVIGNWFWEGDDTSFDPNPKPVSR 195 Score = 46.2 bits (108), Expect = 2e-04 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 10/108 (9%) Query: 687 PAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEE 746 P G S + E ++WFW+ + EA I SW W EE+ G ++ Sbjct: 90 PKAGNESTSSTCKNEAGTDAWFWAGE----EATINSWFWNGEEA-----GNSFSTKNDKP 140 Query: 747 TIINSWFWKEDEAISEATDREESRPEAEEGD-IIGSWFWAGEEDRLEP 793 I +E E + A + S E EE + +IG+WFW G++ +P Sbjct: 141 EIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDP 188 Score = 42.0 bits (97), Expect = 0.004 Identities = 57/251 (22%), Positives = 96/251 (38%), Gaps = 57/251 (22%) Query: 50 ARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTE 109 A KNK++ K A GA ++ PV++ + +A K + Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKA--------------KAK 47 Query: 110 RNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEE 169 S+T+ +A + V+K K ++E +E S P+ F P ++ Sbjct: 48 TGSKTDAVA------EMKAVSKNKVVAETKE----GALSEPKTLGKAMGDFTPKAGNEST 97 Query: 170 TNMGSWCCPRPTSKQEASPNSDFKWV--DKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMH 227 ++ T K EA ++ F W + +++S FW+G+E F N + + Sbjct: 98 SS---------TCKNEAGTDAWF-WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVC 147 Query: 228 MANQE----ANTMSRSQTNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSR- 282 E A+ RS +E E+E+V WFW D T+ DPN + Sbjct: 148 AEELEPAAGADCKPRSGAEEE---------EEENVIGNWFWEGDDTSF------DPNPKP 192 Query: 283 -SRFRSKKEVY 292 SR + VY Sbjct: 193 VSRIVKPQPVY 203 Score = 42.0 bits (97), Expect = 0.004 Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 16/99 (16%) Query: 684 CMYPAGGGSWKSRPEEEEDIVNSWFW---------SRKYTKPEAIIGSWLWATEESNIDG 734 C AG +W EE +NSWFW S K KPE IG+ + A E G Sbjct: 101 CKNEAGTDAWFWAGEEAT--INSWFWNGEEAGNSFSTKNDKPE--IGAQVCAEELEPAAG 156 Query: 735 TGEKAKLLTEEE---TIINSWFWKEDEAISEATDREESR 770 K + EEE +I +WFW+ D+ + + SR Sbjct: 157 ADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSR 195 Score = 38.5 bits (88), Expect = 0.046 Identities = 36/120 (30%), Positives = 46/120 (38%), Gaps = 37/120 (30%) Query: 590 TYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAK 649 T C+ E D A EE I SWFW EA NS S+ DK E I Sbjct: 97 TSSTCKNEAGTDAWFWAGEEATI-NSWFWNGEEA-----GNSFSTKNDKPE--IGAQVCA 148 Query: 650 EEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFW 709 EE ++ G C+ +GAEE EEEE+++ +WFW Sbjct: 149 EE--LEPAAGADCKPRSGAEE---------------------------EEEENVIGNWFW 179 Score = 37.4 bits (85), Expect = 0.10 Identities = 56/220 (25%), Positives = 81/220 (36%), Gaps = 35/220 (15%) Query: 1 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP 60 M G + ++ AQ K EKK + GA E + VVRP +T+A+ A+ K SK Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGA--EREATGVVRPVAKTRAK----AKAKTGSKTDA 54 Query: 61 GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP 120 A K + A K A + P + K P+ G E S T +N Sbjct: 55 VAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDF--TPKAGNESTSSTCKNE-------- 104 Query: 121 LVSTDSVLVAK-----TKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSW 175 TD+ A + E N SF + + G Q E G+ Sbjct: 105 -AGTDAWFWAGEEATINSWFWNGEEAGN----SFSTKNDKPEIGAQVCAEELEPA-AGAD 158 Query: 176 CCPRPTSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHP 215 C PR +++E N W FW GD+ + +P Sbjct: 159 CKPRSGAEEEEEENVIGNW--------FWEGDDTSFDPNP 190 >gi|216547663 basic helix-loop-helix domain containing, class B, 9 [Homo sapiens] Length = 547 Score = 236 bits (601), Expect = 1e-61 Identities = 176/599 (29%), Positives = 299/599 (49%), Gaps = 67/599 (11%) Query: 795 AETREEDRLAA--EKEGIVGSWFGAREET---IRREAGSCSKSSPKAEEEEVIIGSWFWE 849 A T+ + R A EK+ + + GA E +R A + +K+ K + + Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVA----- 56 Query: 850 EEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGS 909 E + V E+K G E T+G + + +AG+ E S + E + Sbjct: 57 -EMKAVSKNKVVAETKEGALSEPKTLGKAMG---DFTPKAGN---ESTSSTCKNEAGTDA 109 Query: 910 WFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEGAIV 969 WFW G EE + SWFW+ ++A + +T KPE + Sbjct: 110 WFWAG------------------EEATINSWFWNGEEA---GNSFSTKNDKPE------I 142 Query: 970 GSWFEAEDEVDNRTDNGSNCGSRTLADEDEA--IVGSWFWAGDEAHFESNPSPVFRAICR 1027 G+ AE+ G++C R+ A+E+E ++G+WFW GD+ F+ NP PV R + Sbjct: 143 GAQVCAEEL---EPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP 199 Query: 1028 STCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRF--PKEAASLFCEMFGGK 1085 E + RP+ W EVT+ P P++ FR P EA+ + Sbjct: 200 QPV---YEINEKNRPKDWSEVTIW----PNAPAVTPAVLGFRSQAPSEASPPSYIVLASA 252 Query: 1086 PRNMVLSPEG---EDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESSSC 1142 N P + QP PE F DP +++ EIR +R +E + +C Sbjct: 253 EENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIRIREVNGIKPFAC 312 Query: 1143 NCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIE 1202 C + E + SEEFE+L+ L++ DP IH+I++IAMG+ + F ++FI + GVV+LIE Sbjct: 313 PC-KMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTLIE 371 Query: 1203 TLLNYPSSRVRTSFLENMIRMAPPYPN--LNIIQTYICKVCEETLAYSVDSPEQLSGIRM 1260 +LL++PS +R + +I + PP + I+ ++ +C+ET+++ ++SP Q SG+++ Sbjct: 372 SLLSFPSPEMRK---KTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSPGQQSGLKI 428 Query: 1261 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS 1320 + LTT +H +VANY S LL++GN KTR VLK+LLN+SEN +++++ +A++ Sbjct: 429 LGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARDMINMKALA 488 Query: 1321 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKEL 1379 +FN++E N+ +AIF NI +I+K ++ D + L++ F +V++ + + Sbjct: 489 ALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREVKEIIETM 547 Score = 67.0 bits (162), Expect = 1e-10 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 17/196 (8%) Query: 372 KKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVED 431 K + RA+A T+++A +A+A A++EA + T A ++ +A E V Sbjct: 5 KNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA-VSK 63 Query: 432 ESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGA-REKTSMKTGAEATSESILA 490 ++ T + S P+T G+ +GD A E TS EA +++ Sbjct: 64 NKVVAE-----------TKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFW 112 Query: 491 ADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCESRTRSEEEE-- 548 A +E I SWFW GEE + + A +E G C+ R+ +EEEE Sbjct: 113 AGEEATI-NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEE 171 Query: 549 -VIGPWFWSGEQVDIE 563 VIG WFW G+ + Sbjct: 172 NVIGNWFWEGDDTSFD 187 Score = 63.2 bits (152), Expect = 2e-09 Identities = 57/204 (27%), Positives = 93/204 (45%), Gaps = 37/204 (18%) Query: 323 AGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMT- 381 AG + RA+ + +++A I G+ E A RP+ K A+A+A T Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGA------------EREATGVVRPVAKTRAKAKAKTG 49 Query: 382 ---------KEEAKTKARARAKQEARSEEEAL---IGTWF-WATDESSMA---DEASIES 425 K +K K A K+ A SE + L +G + A +ES+ + +EA ++ Sbjct: 50 SKTDAVAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDA 109 Query: 426 SLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATS 485 +E+ I SWFW EEA G S+K+ D IG + E+ GA+ Sbjct: 110 WFWAGEEATINSWFWNGEEA--GNSFSTKN----DKPEIGAQV--CAEELEPAAGADCKP 161 Query: 486 ESILAADDEQVIIGSWFWAGEEVN 509 S ++E+ +IG+WFW G++ + Sbjct: 162 RSGAEEEEEENVIGNWFWEGDDTS 185 Score = 49.7 bits (117), Expect = 2e-05 Identities = 59/232 (25%), Positives = 93/232 (40%), Gaps = 40/232 (17%) Query: 228 MANQEANTMSRSQTNQELYIASSSGSEDES--VKTPWFWARDKTNTWSGPREDPNSRSRF 285 MA + T ++++T ++ I + +G+E E+ V P R K +G + D + + Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60 Query: 286 RSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMP 345 SK +V E+ G+ E GK A +AG E+ + K EA D Sbjct: 61 VSKNKVVAETKEGALSEPKT-----LGK-AMGDFTPKAGNESTSST---CKNEAGTDAWF 111 Query: 346 GSIDVIKKESCFWP-EENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEAL 404 + + S FW EE N+FS K E A+ EE + A A K + +EEE Sbjct: 112 WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCA-EELEPAAGADCKPRSGAEEE-- 168 Query: 405 IGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSR 456 E+E++IG+WFW ++ S SR Sbjct: 169 -------------------------EEENVIGNWFWEGDDTSFDPNPKPVSR 195 Score = 46.2 bits (108), Expect = 2e-04 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 10/108 (9%) Query: 687 PAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEE 746 P G S + E ++WFW+ + EA I SW W EE+ G ++ Sbjct: 90 PKAGNESTSSTCKNEAGTDAWFWAGE----EATINSWFWNGEEA-----GNSFSTKNDKP 140 Query: 747 TIINSWFWKEDEAISEATDREESRPEAEEGD-IIGSWFWAGEEDRLEP 793 I +E E + A + S E EE + +IG+WFW G++ +P Sbjct: 141 EIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDP 188 Score = 42.0 bits (97), Expect = 0.004 Identities = 57/251 (22%), Positives = 96/251 (38%), Gaps = 57/251 (22%) Query: 50 ARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTE 109 A KNK++ K A GA ++ PV++ + +A K + Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKA--------------KAK 47 Query: 110 RNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEE 169 S+T+ +A + V+K K ++E +E S P+ F P ++ Sbjct: 48 TGSKTDAVA------EMKAVSKNKVVAETKE----GALSEPKTLGKAMGDFTPKAGNEST 97 Query: 170 TNMGSWCCPRPTSKQEASPNSDFKWV--DKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMH 227 ++ T K EA ++ F W + +++S FW+G+E F N + + Sbjct: 98 SS---------TCKNEAGTDAWF-WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVC 147 Query: 228 MANQE----ANTMSRSQTNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSR- 282 E A+ RS +E E+E+V WFW D T+ DPN + Sbjct: 148 AEELEPAAGADCKPRSGAEEE---------EEENVIGNWFWEGDDTSF------DPNPKP 192 Query: 283 -SRFRSKKEVY 292 SR + VY Sbjct: 193 VSRIVKPQPVY 203 Score = 42.0 bits (97), Expect = 0.004 Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 16/99 (16%) Query: 684 CMYPAGGGSWKSRPEEEEDIVNSWFW---------SRKYTKPEAIIGSWLWATEESNIDG 734 C AG +W EE +NSWFW S K KPE IG+ + A E G Sbjct: 101 CKNEAGTDAWFWAGEEAT--INSWFWNGEEAGNSFSTKNDKPE--IGAQVCAEELEPAAG 156 Query: 735 TGEKAKLLTEEE---TIINSWFWKEDEAISEATDREESR 770 K + EEE +I +WFW+ D+ + + SR Sbjct: 157 ADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSR 195 Score = 38.5 bits (88), Expect = 0.046 Identities = 36/120 (30%), Positives = 46/120 (38%), Gaps = 37/120 (30%) Query: 590 TYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAK 649 T C+ E D A EE I SWFW EA NS S+ DK E I Sbjct: 97 TSSTCKNEAGTDAWFWAGEEATI-NSWFWNGEEA-----GNSFSTKNDKPE--IGAQVCA 148 Query: 650 EEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFW 709 EE ++ G C+ +GAEE EEEE+++ +WFW Sbjct: 149 EE--LEPAAGADCKPRSGAEE---------------------------EEEENVIGNWFW 179 Score = 37.4 bits (85), Expect = 0.10 Identities = 56/220 (25%), Positives = 81/220 (36%), Gaps = 35/220 (15%) Query: 1 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP 60 M G + ++ AQ K EKK + GA E + VVRP +T+A+ A+ K SK Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGA--EREATGVVRPVAKTRAK----AKAKTGSKTDA 54 Query: 61 GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP 120 A K + A K A + P + K P+ G E S T +N Sbjct: 55 VAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDF--TPKAGNESTSSTCKNE-------- 104 Query: 121 LVSTDSVLVAK-----TKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSW 175 TD+ A + E N SF + + G Q E G+ Sbjct: 105 -AGTDAWFWAGEEATINSWFWNGEEAGN----SFSTKNDKPEIGAQVCAEELEPA-AGAD 158 Query: 176 CCPRPTSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHP 215 C PR +++E N W FW GD+ + +P Sbjct: 159 CKPRSGAEEEEEENVIGNW--------FWEGDDTSFDPNP 190 >gi|216547655 basic helix-loop-helix domain containing, class B, 9 [Homo sapiens] Length = 547 Score = 236 bits (601), Expect = 1e-61 Identities = 176/599 (29%), Positives = 299/599 (49%), Gaps = 67/599 (11%) Query: 795 AETREEDRLAA--EKEGIVGSWFGAREET---IRREAGSCSKSSPKAEEEEVIIGSWFWE 849 A T+ + R A EK+ + + GA E +R A + +K+ K + + Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVA----- 56 Query: 850 EEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGS 909 E + V E+K G E T+G + + +AG+ E S + E + Sbjct: 57 -EMKAVSKNKVVAETKEGALSEPKTLGKAMG---DFTPKAGN---ESTSSTCKNEAGTDA 109 Query: 910 WFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEGAIV 969 WFW G EE + SWFW+ ++A + +T KPE + Sbjct: 110 WFWAG------------------EEATINSWFWNGEEA---GNSFSTKNDKPE------I 142 Query: 970 GSWFEAEDEVDNRTDNGSNCGSRTLADEDEA--IVGSWFWAGDEAHFESNPSPVFRAICR 1027 G+ AE+ G++C R+ A+E+E ++G+WFW GD+ F+ NP PV R + Sbjct: 143 GAQVCAEEL---EPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP 199 Query: 1028 STCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRF--PKEAASLFCEMFGGK 1085 E + RP+ W EVT+ P P++ FR P EA+ + Sbjct: 200 QPV---YEINEKNRPKDWSEVTIW----PNAPAVTPAVLGFRSQAPSEASPPSYIVLASA 252 Query: 1086 PRNMVLSPEG---EDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESSSC 1142 N P + QP PE F DP +++ EIR +R +E + +C Sbjct: 253 EENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIRIREVNGIKPFAC 312 Query: 1143 NCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIE 1202 C + E + SEEFE+L+ L++ DP IH+I++IAMG+ + F ++FI + GVV+LIE Sbjct: 313 PC-KMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTLIE 371 Query: 1203 TLLNYPSSRVRTSFLENMIRMAPPYPN--LNIIQTYICKVCEETLAYSVDSPEQLSGIRM 1260 +LL++PS +R + +I + PP + I+ ++ +C+ET+++ ++SP Q SG+++ Sbjct: 372 SLLSFPSPEMRK---KTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSPGQQSGLKI 428 Query: 1261 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS 1320 + LTT +H +VANY S LL++GN KTR VLK+LLN+SEN +++++ +A++ Sbjct: 429 LGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARDMINMKALA 488 Query: 1321 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKEL 1379 +FN++E N+ +AIF NI +I+K ++ D + L++ F +V++ + + Sbjct: 489 ALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREVKEIIETM 547 Score = 67.0 bits (162), Expect = 1e-10 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 17/196 (8%) Query: 372 KKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVED 431 K + RA+A T+++A +A+A A++EA + T A ++ +A E V Sbjct: 5 KNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA-VSK 63 Query: 432 ESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGA-REKTSMKTGAEATSESILA 490 ++ T + S P+T G+ +GD A E TS EA +++ Sbjct: 64 NKVVAE-----------TKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFW 112 Query: 491 ADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCESRTRSEEEE-- 548 A +E I SWFW GEE + + A +E G C+ R+ +EEEE Sbjct: 113 AGEEATI-NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEE 171 Query: 549 -VIGPWFWSGEQVDIE 563 VIG WFW G+ + Sbjct: 172 NVIGNWFWEGDDTSFD 187 Score = 63.2 bits (152), Expect = 2e-09 Identities = 57/204 (27%), Positives = 93/204 (45%), Gaps = 37/204 (18%) Query: 323 AGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMT- 381 AG + RA+ + +++A I G+ E A RP+ K A+A+A T Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGA------------EREATGVVRPVAKTRAKAKAKTG 49 Query: 382 ---------KEEAKTKARARAKQEARSEEEAL---IGTWF-WATDESSMA---DEASIES 425 K +K K A K+ A SE + L +G + A +ES+ + +EA ++ Sbjct: 50 SKTDAVAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDA 109 Query: 426 SLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATS 485 +E+ I SWFW EEA G S+K+ D IG + E+ GA+ Sbjct: 110 WFWAGEEATINSWFWNGEEA--GNSFSTKN----DKPEIGAQV--CAEELEPAAGADCKP 161 Query: 486 ESILAADDEQVIIGSWFWAGEEVN 509 S ++E+ +IG+WFW G++ + Sbjct: 162 RSGAEEEEEENVIGNWFWEGDDTS 185 Score = 49.7 bits (117), Expect = 2e-05 Identities = 59/232 (25%), Positives = 93/232 (40%), Gaps = 40/232 (17%) Query: 228 MANQEANTMSRSQTNQELYIASSSGSEDES--VKTPWFWARDKTNTWSGPREDPNSRSRF 285 MA + T ++++T ++ I + +G+E E+ V P R K +G + D + + Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60 Query: 286 RSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMP 345 SK +V E+ G+ E GK A +AG E+ + K EA D Sbjct: 61 VSKNKVVAETKEGALSEPKT-----LGK-AMGDFTPKAGNESTSST---CKNEAGTDAWF 111 Query: 346 GSIDVIKKESCFWP-EENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEAL 404 + + S FW EE N+FS K E A+ EE + A A K + +EEE Sbjct: 112 WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCA-EELEPAAGADCKPRSGAEEE-- 168 Query: 405 IGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSR 456 E+E++IG+WFW ++ S SR Sbjct: 169 -------------------------EEENVIGNWFWEGDDTSFDPNPKPVSR 195 Score = 46.2 bits (108), Expect = 2e-04 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 10/108 (9%) Query: 687 PAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEE 746 P G S + E ++WFW+ + EA I SW W EE+ G ++ Sbjct: 90 PKAGNESTSSTCKNEAGTDAWFWAGE----EATINSWFWNGEEA-----GNSFSTKNDKP 140 Query: 747 TIINSWFWKEDEAISEATDREESRPEAEEGD-IIGSWFWAGEEDRLEP 793 I +E E + A + S E EE + +IG+WFW G++ +P Sbjct: 141 EIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDP 188 Score = 42.0 bits (97), Expect = 0.004 Identities = 57/251 (22%), Positives = 96/251 (38%), Gaps = 57/251 (22%) Query: 50 ARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTE 109 A KNK++ K A GA ++ PV++ + +A K + Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKA--------------KAK 47 Query: 110 RNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEE 169 S+T+ +A + V+K K ++E +E S P+ F P ++ Sbjct: 48 TGSKTDAVA------EMKAVSKNKVVAETKE----GALSEPKTLGKAMGDFTPKAGNEST 97 Query: 170 TNMGSWCCPRPTSKQEASPNSDFKWV--DKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMH 227 ++ T K EA ++ F W + +++S FW+G+E F N + + Sbjct: 98 SS---------TCKNEAGTDAWF-WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVC 147 Query: 228 MANQE----ANTMSRSQTNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSR- 282 E A+ RS +E E+E+V WFW D T+ DPN + Sbjct: 148 AEELEPAAGADCKPRSGAEEE---------EEENVIGNWFWEGDDTSF------DPNPKP 192 Query: 283 -SRFRSKKEVY 292 SR + VY Sbjct: 193 VSRIVKPQPVY 203 Score = 42.0 bits (97), Expect = 0.004 Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 16/99 (16%) Query: 684 CMYPAGGGSWKSRPEEEEDIVNSWFW---------SRKYTKPEAIIGSWLWATEESNIDG 734 C AG +W EE +NSWFW S K KPE IG+ + A E G Sbjct: 101 CKNEAGTDAWFWAGEEAT--INSWFWNGEEAGNSFSTKNDKPE--IGAQVCAEELEPAAG 156 Query: 735 TGEKAKLLTEEE---TIINSWFWKEDEAISEATDREESR 770 K + EEE +I +WFW+ D+ + + SR Sbjct: 157 ADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSR 195 Score = 38.5 bits (88), Expect = 0.046 Identities = 36/120 (30%), Positives = 46/120 (38%), Gaps = 37/120 (30%) Query: 590 TYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAK 649 T C+ E D A EE I SWFW EA NS S+ DK E I Sbjct: 97 TSSTCKNEAGTDAWFWAGEEATI-NSWFWNGEEA-----GNSFSTKNDKPE--IGAQVCA 148 Query: 650 EEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFW 709 EE ++ G C+ +GAEE EEEE+++ +WFW Sbjct: 149 EE--LEPAAGADCKPRSGAEE---------------------------EEEENVIGNWFW 179 Score = 37.4 bits (85), Expect = 0.10 Identities = 56/220 (25%), Positives = 81/220 (36%), Gaps = 35/220 (15%) Query: 1 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP 60 M G + ++ AQ K EKK + GA E + VVRP +T+A+ A+ K SK Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGA--EREATGVVRPVAKTRAK----AKAKTGSKTDA 54 Query: 61 GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP 120 A K + A K A + P + K P+ G E S T +N Sbjct: 55 VAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDF--TPKAGNESTSSTCKNE-------- 104 Query: 121 LVSTDSVLVAK-----TKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSW 175 TD+ A + E N SF + + G Q E G+ Sbjct: 105 -AGTDAWFWAGEEATINSWFWNGEEAGN----SFSTKNDKPEIGAQVCAEELEPA-AGAD 158 Query: 176 CCPRPTSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHP 215 C PR +++E N W FW GD+ + +P Sbjct: 159 CKPRSGAEEEEEENVIGNW--------FWEGDDTSFDPNP 190 >gi|216547646 basic helix-loop-helix domain containing, class B, 9 [Homo sapiens] Length = 547 Score = 236 bits (601), Expect = 1e-61 Identities = 176/599 (29%), Positives = 299/599 (49%), Gaps = 67/599 (11%) Query: 795 AETREEDRLAA--EKEGIVGSWFGAREET---IRREAGSCSKSSPKAEEEEVIIGSWFWE 849 A T+ + R A EK+ + + GA E +R A + +K+ K + + Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVA----- 56 Query: 850 EEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGS 909 E + V E+K G E T+G + + +AG+ E S + E + Sbjct: 57 -EMKAVSKNKVVAETKEGALSEPKTLGKAMG---DFTPKAGN---ESTSSTCKNEAGTDA 109 Query: 910 WFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEGAIV 969 WFW G EE + SWFW+ ++A + +T KPE + Sbjct: 110 WFWAG------------------EEATINSWFWNGEEA---GNSFSTKNDKPE------I 142 Query: 970 GSWFEAEDEVDNRTDNGSNCGSRTLADEDEA--IVGSWFWAGDEAHFESNPSPVFRAICR 1027 G+ AE+ G++C R+ A+E+E ++G+WFW GD+ F+ NP PV R + Sbjct: 143 GAQVCAEEL---EPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP 199 Query: 1028 STCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRF--PKEAASLFCEMFGGK 1085 E + RP+ W EVT+ P P++ FR P EA+ + Sbjct: 200 QPV---YEINEKNRPKDWSEVTIW----PNAPAVTPAVLGFRSQAPSEASPPSYIVLASA 252 Query: 1086 PRNMVLSPEG---EDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESSSC 1142 N P + QP PE F DP +++ EIR +R +E + +C Sbjct: 253 EENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIRIREVNGIKPFAC 312 Query: 1143 NCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIE 1202 C + E + SEEFE+L+ L++ DP IH+I++IAMG+ + F ++FI + GVV+LIE Sbjct: 313 PC-KMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTLIE 371 Query: 1203 TLLNYPSSRVRTSFLENMIRMAPPYPN--LNIIQTYICKVCEETLAYSVDSPEQLSGIRM 1260 +LL++PS +R + +I + PP + I+ ++ +C+ET+++ ++SP Q SG+++ Sbjct: 372 SLLSFPSPEMRK---KTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSPGQQSGLKI 428 Query: 1261 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS 1320 + LTT +H +VANY S LL++GN KTR VLK+LLN+SEN +++++ +A++ Sbjct: 429 LGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARDMINMKALA 488 Query: 1321 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKEL 1379 +FN++E N+ +AIF NI +I+K ++ D + L++ F +V++ + + Sbjct: 489 ALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREVKEIIETM 547 Score = 67.0 bits (162), Expect = 1e-10 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 17/196 (8%) Query: 372 KKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVED 431 K + RA+A T+++A +A+A A++EA + T A ++ +A E V Sbjct: 5 KNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA-VSK 63 Query: 432 ESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGA-REKTSMKTGAEATSESILA 490 ++ T + S P+T G+ +GD A E TS EA +++ Sbjct: 64 NKVVAE-----------TKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFW 112 Query: 491 ADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCESRTRSEEEE-- 548 A +E I SWFW GEE + + A +E G C+ R+ +EEEE Sbjct: 113 AGEEATI-NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEE 171 Query: 549 -VIGPWFWSGEQVDIE 563 VIG WFW G+ + Sbjct: 172 NVIGNWFWEGDDTSFD 187 Score = 63.2 bits (152), Expect = 2e-09 Identities = 57/204 (27%), Positives = 93/204 (45%), Gaps = 37/204 (18%) Query: 323 AGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMT- 381 AG + RA+ + +++A I G+ E A RP+ K A+A+A T Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGA------------EREATGVVRPVAKTRAKAKAKTG 49 Query: 382 ---------KEEAKTKARARAKQEARSEEEAL---IGTWF-WATDESSMA---DEASIES 425 K +K K A K+ A SE + L +G + A +ES+ + +EA ++ Sbjct: 50 SKTDAVAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDA 109 Query: 426 SLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATS 485 +E+ I SWFW EEA G S+K+ D IG + E+ GA+ Sbjct: 110 WFWAGEEATINSWFWNGEEA--GNSFSTKN----DKPEIGAQV--CAEELEPAAGADCKP 161 Query: 486 ESILAADDEQVIIGSWFWAGEEVN 509 S ++E+ +IG+WFW G++ + Sbjct: 162 RSGAEEEEEENVIGNWFWEGDDTS 185 Score = 49.7 bits (117), Expect = 2e-05 Identities = 59/232 (25%), Positives = 93/232 (40%), Gaps = 40/232 (17%) Query: 228 MANQEANTMSRSQTNQELYIASSSGSEDES--VKTPWFWARDKTNTWSGPREDPNSRSRF 285 MA + T ++++T ++ I + +G+E E+ V P R K +G + D + + Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60 Query: 286 RSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMP 345 SK +V E+ G+ E GK A +AG E+ + K EA D Sbjct: 61 VSKNKVVAETKEGALSEPKT-----LGK-AMGDFTPKAGNESTSST---CKNEAGTDAWF 111 Query: 346 GSIDVIKKESCFWP-EENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEAL 404 + + S FW EE N+FS K E A+ EE + A A K + +EEE Sbjct: 112 WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCA-EELEPAAGADCKPRSGAEEE-- 168 Query: 405 IGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSR 456 E+E++IG+WFW ++ S SR Sbjct: 169 -------------------------EEENVIGNWFWEGDDTSFDPNPKPVSR 195 Score = 46.2 bits (108), Expect = 2e-04 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 10/108 (9%) Query: 687 PAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEE 746 P G S + E ++WFW+ + EA I SW W EE+ G ++ Sbjct: 90 PKAGNESTSSTCKNEAGTDAWFWAGE----EATINSWFWNGEEA-----GNSFSTKNDKP 140 Query: 747 TIINSWFWKEDEAISEATDREESRPEAEEGD-IIGSWFWAGEEDRLEP 793 I +E E + A + S E EE + +IG+WFW G++ +P Sbjct: 141 EIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDP 188 Score = 42.0 bits (97), Expect = 0.004 Identities = 57/251 (22%), Positives = 96/251 (38%), Gaps = 57/251 (22%) Query: 50 ARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTE 109 A KNK++ K A GA ++ PV++ + +A K + Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKA--------------KAK 47 Query: 110 RNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEE 169 S+T+ +A + V+K K ++E +E S P+ F P ++ Sbjct: 48 TGSKTDAVA------EMKAVSKNKVVAETKE----GALSEPKTLGKAMGDFTPKAGNEST 97 Query: 170 TNMGSWCCPRPTSKQEASPNSDFKWV--DKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMH 227 ++ T K EA ++ F W + +++S FW+G+E F N + + Sbjct: 98 SS---------TCKNEAGTDAWF-WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVC 147 Query: 228 MANQE----ANTMSRSQTNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSR- 282 E A+ RS +E E+E+V WFW D T+ DPN + Sbjct: 148 AEELEPAAGADCKPRSGAEEE---------EEENVIGNWFWEGDDTSF------DPNPKP 192 Query: 283 -SRFRSKKEVY 292 SR + VY Sbjct: 193 VSRIVKPQPVY 203 Score = 42.0 bits (97), Expect = 0.004 Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 16/99 (16%) Query: 684 CMYPAGGGSWKSRPEEEEDIVNSWFW---------SRKYTKPEAIIGSWLWATEESNIDG 734 C AG +W EE +NSWFW S K KPE IG+ + A E G Sbjct: 101 CKNEAGTDAWFWAGEEAT--INSWFWNGEEAGNSFSTKNDKPE--IGAQVCAEELEPAAG 156 Query: 735 TGEKAKLLTEEE---TIINSWFWKEDEAISEATDREESR 770 K + EEE +I +WFW+ D+ + + SR Sbjct: 157 ADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSR 195 Score = 38.5 bits (88), Expect = 0.046 Identities = 36/120 (30%), Positives = 46/120 (38%), Gaps = 37/120 (30%) Query: 590 TYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAK 649 T C+ E D A EE I SWFW EA NS S+ DK E I Sbjct: 97 TSSTCKNEAGTDAWFWAGEEATI-NSWFWNGEEA-----GNSFSTKNDKPE--IGAQVCA 148 Query: 650 EEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFW 709 EE ++ G C+ +GAEE EEEE+++ +WFW Sbjct: 149 EE--LEPAAGADCKPRSGAEE---------------------------EEEENVIGNWFW 179 Score = 37.4 bits (85), Expect = 0.10 Identities = 56/220 (25%), Positives = 81/220 (36%), Gaps = 35/220 (15%) Query: 1 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP 60 M G + ++ AQ K EKK + GA E + VVRP +T+A+ A+ K SK Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGA--EREATGVVRPVAKTRAK----AKAKTGSKTDA 54 Query: 61 GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP 120 A K + A K A + P + K P+ G E S T +N Sbjct: 55 VAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDF--TPKAGNESTSSTCKNE-------- 104 Query: 121 LVSTDSVLVAK-----TKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSW 175 TD+ A + E N SF + + G Q E G+ Sbjct: 105 -AGTDAWFWAGEEATINSWFWNGEEAGN----SFSTKNDKPEIGAQVCAEELEPA-AGAD 158 Query: 176 CCPRPTSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHP 215 C PR +++E N W FW GD+ + +P Sbjct: 159 CKPRSGAEEEEEENVIGNW--------FWEGDDTSFDPNP 190 >gi|216547639 basic helix-loop-helix domain containing, class B, 9 [Homo sapiens] Length = 547 Score = 236 bits (601), Expect = 1e-61 Identities = 176/599 (29%), Positives = 299/599 (49%), Gaps = 67/599 (11%) Query: 795 AETREEDRLAA--EKEGIVGSWFGAREET---IRREAGSCSKSSPKAEEEEVIIGSWFWE 849 A T+ + R A EK+ + + GA E +R A + +K+ K + + Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVA----- 56 Query: 850 EEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGS 909 E + V E+K G E T+G + + +AG+ E S + E + Sbjct: 57 -EMKAVSKNKVVAETKEGALSEPKTLGKAMG---DFTPKAGN---ESTSSTCKNEAGTDA 109 Query: 910 WFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEGAIV 969 WFW G EE + SWFW+ ++A + +T KPE + Sbjct: 110 WFWAG------------------EEATINSWFWNGEEA---GNSFSTKNDKPE------I 142 Query: 970 GSWFEAEDEVDNRTDNGSNCGSRTLADEDEA--IVGSWFWAGDEAHFESNPSPVFRAICR 1027 G+ AE+ G++C R+ A+E+E ++G+WFW GD+ F+ NP PV R + Sbjct: 143 GAQVCAEEL---EPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP 199 Query: 1028 STCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRF--PKEAASLFCEMFGGK 1085 E + RP+ W EVT+ P P++ FR P EA+ + Sbjct: 200 QPV---YEINEKNRPKDWSEVTIW----PNAPAVTPAVLGFRSQAPSEASPPSYIVLASA 252 Query: 1086 PRNMVLSPEG---EDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESSSC 1142 N P + QP PE F DP +++ EIR +R +E + +C Sbjct: 253 EENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIRIREVNGIKPFAC 312 Query: 1143 NCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIE 1202 C + E + SEEFE+L+ L++ DP IH+I++IAMG+ + F ++FI + GVV+LIE Sbjct: 313 PC-KMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTLIE 371 Query: 1203 TLLNYPSSRVRTSFLENMIRMAPPYPN--LNIIQTYICKVCEETLAYSVDSPEQLSGIRM 1260 +LL++PS +R + +I + PP + I+ ++ +C+ET+++ ++SP Q SG+++ Sbjct: 372 SLLSFPSPEMRK---KTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSPGQQSGLKI 428 Query: 1261 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS 1320 + LTT +H +VANY S LL++GN KTR VLK+LLN+SEN +++++ +A++ Sbjct: 429 LGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARDMINMKALA 488 Query: 1321 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKEL 1379 +FN++E N+ +AIF NI +I+K ++ D + L++ F +V++ + + Sbjct: 489 ALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREVKEIIETM 547 Score = 67.0 bits (162), Expect = 1e-10 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 17/196 (8%) Query: 372 KKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVED 431 K + RA+A T+++A +A+A A++EA + T A ++ +A E V Sbjct: 5 KNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA-VSK 63 Query: 432 ESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGA-REKTSMKTGAEATSESILA 490 ++ T + S P+T G+ +GD A E TS EA +++ Sbjct: 64 NKVVAE-----------TKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFW 112 Query: 491 ADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCESRTRSEEEE-- 548 A +E I SWFW GEE + + A +E G C+ R+ +EEEE Sbjct: 113 AGEEATI-NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEE 171 Query: 549 -VIGPWFWSGEQVDIE 563 VIG WFW G+ + Sbjct: 172 NVIGNWFWEGDDTSFD 187 Score = 63.2 bits (152), Expect = 2e-09 Identities = 57/204 (27%), Positives = 93/204 (45%), Gaps = 37/204 (18%) Query: 323 AGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMT- 381 AG + RA+ + +++A I G+ E A RP+ K A+A+A T Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGA------------EREATGVVRPVAKTRAKAKAKTG 49 Query: 382 ---------KEEAKTKARARAKQEARSEEEAL---IGTWF-WATDESSMA---DEASIES 425 K +K K A K+ A SE + L +G + A +ES+ + +EA ++ Sbjct: 50 SKTDAVAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDA 109 Query: 426 SLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATS 485 +E+ I SWFW EEA G S+K+ D IG + E+ GA+ Sbjct: 110 WFWAGEEATINSWFWNGEEA--GNSFSTKN----DKPEIGAQV--CAEELEPAAGADCKP 161 Query: 486 ESILAADDEQVIIGSWFWAGEEVN 509 S ++E+ +IG+WFW G++ + Sbjct: 162 RSGAEEEEEENVIGNWFWEGDDTS 185 Score = 49.7 bits (117), Expect = 2e-05 Identities = 59/232 (25%), Positives = 93/232 (40%), Gaps = 40/232 (17%) Query: 228 MANQEANTMSRSQTNQELYIASSSGSEDES--VKTPWFWARDKTNTWSGPREDPNSRSRF 285 MA + T ++++T ++ I + +G+E E+ V P R K +G + D + + Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60 Query: 286 RSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMP 345 SK +V E+ G+ E GK A +AG E+ + K EA D Sbjct: 61 VSKNKVVAETKEGALSEPKT-----LGK-AMGDFTPKAGNESTSST---CKNEAGTDAWF 111 Query: 346 GSIDVIKKESCFWP-EENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEAL 404 + + S FW EE N+FS K E A+ EE + A A K + +EEE Sbjct: 112 WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCA-EELEPAAGADCKPRSGAEEE-- 168 Query: 405 IGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSR 456 E+E++IG+WFW ++ S SR Sbjct: 169 -------------------------EEENVIGNWFWEGDDTSFDPNPKPVSR 195 Score = 46.2 bits (108), Expect = 2e-04 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 10/108 (9%) Query: 687 PAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEE 746 P G S + E ++WFW+ + EA I SW W EE+ G ++ Sbjct: 90 PKAGNESTSSTCKNEAGTDAWFWAGE----EATINSWFWNGEEA-----GNSFSTKNDKP 140 Query: 747 TIINSWFWKEDEAISEATDREESRPEAEEGD-IIGSWFWAGEEDRLEP 793 I +E E + A + S E EE + +IG+WFW G++ +P Sbjct: 141 EIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDP 188 Score = 42.0 bits (97), Expect = 0.004 Identities = 57/251 (22%), Positives = 96/251 (38%), Gaps = 57/251 (22%) Query: 50 ARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTE 109 A KNK++ K A GA ++ PV++ + +A K + Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKA--------------KAK 47 Query: 110 RNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEE 169 S+T+ +A + V+K K ++E +E S P+ F P ++ Sbjct: 48 TGSKTDAVA------EMKAVSKNKVVAETKE----GALSEPKTLGKAMGDFTPKAGNEST 97 Query: 170 TNMGSWCCPRPTSKQEASPNSDFKWV--DKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMH 227 ++ T K EA ++ F W + +++S FW+G+E F N + + Sbjct: 98 SS---------TCKNEAGTDAWF-WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVC 147 Query: 228 MANQE----ANTMSRSQTNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSR- 282 E A+ RS +E E+E+V WFW D T+ DPN + Sbjct: 148 AEELEPAAGADCKPRSGAEEE---------EEENVIGNWFWEGDDTSF------DPNPKP 192 Query: 283 -SRFRSKKEVY 292 SR + VY Sbjct: 193 VSRIVKPQPVY 203 Score = 42.0 bits (97), Expect = 0.004 Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 16/99 (16%) Query: 684 CMYPAGGGSWKSRPEEEEDIVNSWFW---------SRKYTKPEAIIGSWLWATEESNIDG 734 C AG +W EE +NSWFW S K KPE IG+ + A E G Sbjct: 101 CKNEAGTDAWFWAGEEAT--INSWFWNGEEAGNSFSTKNDKPE--IGAQVCAEELEPAAG 156 Query: 735 TGEKAKLLTEEE---TIINSWFWKEDEAISEATDREESR 770 K + EEE +I +WFW+ D+ + + SR Sbjct: 157 ADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSR 195 Score = 38.5 bits (88), Expect = 0.046 Identities = 36/120 (30%), Positives = 46/120 (38%), Gaps = 37/120 (30%) Query: 590 TYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAK 649 T C+ E D A EE I SWFW EA NS S+ DK E I Sbjct: 97 TSSTCKNEAGTDAWFWAGEEATI-NSWFWNGEEA-----GNSFSTKNDKPE--IGAQVCA 148 Query: 650 EEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFW 709 EE ++ G C+ +GAEE EEEE+++ +WFW Sbjct: 149 EE--LEPAAGADCKPRSGAEE---------------------------EEEENVIGNWFW 179 Score = 37.4 bits (85), Expect = 0.10 Identities = 56/220 (25%), Positives = 81/220 (36%), Gaps = 35/220 (15%) Query: 1 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP 60 M G + ++ AQ K EKK + GA E + VVRP +T+A+ A+ K SK Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGA--EREATGVVRPVAKTRAK----AKAKTGSKTDA 54 Query: 61 GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP 120 A K + A K A + P + K P+ G E S T +N Sbjct: 55 VAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDF--TPKAGNESTSSTCKNE-------- 104 Query: 121 LVSTDSVLVAK-----TKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSW 175 TD+ A + E N SF + + G Q E G+ Sbjct: 105 -AGTDAWFWAGEEATINSWFWNGEEAGN----SFSTKNDKPEIGAQVCAEELEPA-AGAD 158 Query: 176 CCPRPTSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHP 215 C PR +++E N W FW GD+ + +P Sbjct: 159 CKPRSGAEEEEEENVIGNW--------FWEGDDTSFDPNP 190 >gi|39930463 basic helix-loop-helix domain containing, class B, 9 [Homo sapiens] Length = 547 Score = 236 bits (601), Expect = 1e-61 Identities = 176/599 (29%), Positives = 299/599 (49%), Gaps = 67/599 (11%) Query: 795 AETREEDRLAA--EKEGIVGSWFGAREET---IRREAGSCSKSSPKAEEEEVIIGSWFWE 849 A T+ + R A EK+ + + GA E +R A + +K+ K + + Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVA----- 56 Query: 850 EEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGS 909 E + V E+K G E T+G + + +AG+ E S + E + Sbjct: 57 -EMKAVSKNKVVAETKEGALSEPKTLGKAMG---DFTPKAGN---ESTSSTCKNEAGTDA 109 Query: 910 WFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEGAIV 969 WFW G EE + SWFW+ ++A + +T KPE + Sbjct: 110 WFWAG------------------EEATINSWFWNGEEA---GNSFSTKNDKPE------I 142 Query: 970 GSWFEAEDEVDNRTDNGSNCGSRTLADEDEA--IVGSWFWAGDEAHFESNPSPVFRAICR 1027 G+ AE+ G++C R+ A+E+E ++G+WFW GD+ F+ NP PV R + Sbjct: 143 GAQVCAEEL---EPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP 199 Query: 1028 STCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRF--PKEAASLFCEMFGGK 1085 E + RP+ W EVT+ P P++ FR P EA+ + Sbjct: 200 QPV---YEINEKNRPKDWSEVTIW----PNAPAVTPAVLGFRSQAPSEASPPSYIVLASA 252 Query: 1086 PRNMVLSPEG---EDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESSSC 1142 N P + QP PE F DP +++ EIR +R +E + +C Sbjct: 253 EENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIRIREVNGIKPFAC 312 Query: 1143 NCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIE 1202 C + E + SEEFE+L+ L++ DP IH+I++IAMG+ + F ++FI + GVV+LIE Sbjct: 313 PC-KMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTLIE 371 Query: 1203 TLLNYPSSRVRTSFLENMIRMAPPYPN--LNIIQTYICKVCEETLAYSVDSPEQLSGIRM 1260 +LL++PS +R + +I + PP + I+ ++ +C+ET+++ ++SP Q SG+++ Sbjct: 372 SLLSFPSPEMRK---KTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSPGQQSGLKI 428 Query: 1261 IRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVS 1320 + LTT +H +VANY S LL++GN KTR VLK+LLN+SEN +++++ +A++ Sbjct: 429 LGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARDMINMKALA 488 Query: 1321 EFIGLFNREETNDNIQIVLAIFENIGNNIKKETVFSDDDFNIEPLISAFHKVEKFAKEL 1379 +FN++E N+ +AIF NI +I+K ++ D + L++ F +V++ + + Sbjct: 489 ALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREVKEIIETM 547 Score = 67.0 bits (162), Expect = 1e-10 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 17/196 (8%) Query: 372 KKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVED 431 K + RA+A T+++A +A+A A++EA + T A ++ +A E V Sbjct: 5 KNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA-VSK 63 Query: 432 ESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGA-REKTSMKTGAEATSESILA 490 ++ T + S P+T G+ +GD A E TS EA +++ Sbjct: 64 NKVVAE-----------TKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFW 112 Query: 491 ADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCESRTRSEEEE-- 548 A +E I SWFW GEE + + A +E G C+ R+ +EEEE Sbjct: 113 AGEEATI-NSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEE 171 Query: 549 -VIGPWFWSGEQVDIE 563 VIG WFW G+ + Sbjct: 172 NVIGNWFWEGDDTSFD 187 Score = 63.2 bits (152), Expect = 2e-09 Identities = 57/204 (27%), Positives = 93/204 (45%), Gaps = 37/204 (18%) Query: 323 AGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMT- 381 AG + RA+ + +++A I G+ E A RP+ K A+A+A T Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGA------------EREATGVVRPVAKTRAKAKAKTG 49 Query: 382 ---------KEEAKTKARARAKQEARSEEEAL---IGTWF-WATDESSMA---DEASIES 425 K +K K A K+ A SE + L +G + A +ES+ + +EA ++ Sbjct: 50 SKTDAVAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDA 109 Query: 426 SLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATS 485 +E+ I SWFW EEA G S+K+ D IG + E+ GA+ Sbjct: 110 WFWAGEEATINSWFWNGEEA--GNSFSTKN----DKPEIGAQV--CAEELEPAAGADCKP 161 Query: 486 ESILAADDEQVIIGSWFWAGEEVN 509 S ++E+ +IG+WFW G++ + Sbjct: 162 RSGAEEEEEENVIGNWFWEGDDTS 185 Score = 49.7 bits (117), Expect = 2e-05 Identities = 59/232 (25%), Positives = 93/232 (40%), Gaps = 40/232 (17%) Query: 228 MANQEANTMSRSQTNQELYIASSSGSEDES--VKTPWFWARDKTNTWSGPREDPNSRSRF 285 MA + T ++++T ++ I + +G+E E+ V P R K +G + D + + Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60 Query: 286 RSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRAGKEANNRARHRAKREACIDFMP 345 SK +V E+ G+ E GK A +AG E+ + K EA D Sbjct: 61 VSKNKVVAETKEGALSEPKT-----LGK-AMGDFTPKAGNESTSST---CKNEAGTDAWF 111 Query: 346 GSIDVIKKESCFWP-EENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEAL 404 + + S FW EE N+FS K E A+ EE + A A K + +EEE Sbjct: 112 WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCA-EELEPAAGADCKPRSGAEEE-- 168 Query: 405 IGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSR 456 E+E++IG+WFW ++ S SR Sbjct: 169 -------------------------EEENVIGNWFWEGDDTSFDPNPKPVSR 195 Score = 46.2 bits (108), Expect = 2e-04 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 10/108 (9%) Query: 687 PAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEE 746 P G S + E ++WFW+ + EA I SW W EE+ G ++ Sbjct: 90 PKAGNESTSSTCKNEAGTDAWFWAGE----EATINSWFWNGEEA-----GNSFSTKNDKP 140 Query: 747 TIINSWFWKEDEAISEATDREESRPEAEEGD-IIGSWFWAGEEDRLEP 793 I +E E + A + S E EE + +IG+WFW G++ +P Sbjct: 141 EIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDP 188 Score = 42.0 bits (97), Expect = 0.004 Identities = 57/251 (22%), Positives = 96/251 (38%), Gaps = 57/251 (22%) Query: 50 ARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTE 109 A KNK++ K A GA ++ PV++ + +A K + Sbjct: 2 AGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKA--------------KAK 47 Query: 110 RNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEE 169 S+T+ +A + V+K K ++E +E S P+ F P ++ Sbjct: 48 TGSKTDAVA------EMKAVSKNKVVAETKE----GALSEPKTLGKAMGDFTPKAGNEST 97 Query: 170 TNMGSWCCPRPTSKQEASPNSDFKWV--DKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMH 227 ++ T K EA ++ F W + +++S FW+G+E F N + + Sbjct: 98 SS---------TCKNEAGTDAWF-WAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVC 147 Query: 228 MANQE----ANTMSRSQTNQELYIASSSGSEDESVKTPWFWARDKTNTWSGPREDPNSR- 282 E A+ RS +E E+E+V WFW D T+ DPN + Sbjct: 148 AEELEPAAGADCKPRSGAEEE---------EEENVIGNWFWEGDDTSF------DPNPKP 192 Query: 283 -SRFRSKKEVY 292 SR + VY Sbjct: 193 VSRIVKPQPVY 203 Score = 42.0 bits (97), Expect = 0.004 Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 16/99 (16%) Query: 684 CMYPAGGGSWKSRPEEEEDIVNSWFW---------SRKYTKPEAIIGSWLWATEESNIDG 734 C AG +W EE +NSWFW S K KPE IG+ + A E G Sbjct: 101 CKNEAGTDAWFWAGEEAT--INSWFWNGEEAGNSFSTKNDKPE--IGAQVCAEELEPAAG 156 Query: 735 TGEKAKLLTEEE---TIINSWFWKEDEAISEATDREESR 770 K + EEE +I +WFW+ D+ + + SR Sbjct: 157 ADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSR 195 Score = 38.5 bits (88), Expect = 0.046 Identities = 36/120 (30%), Positives = 46/120 (38%), Gaps = 37/120 (30%) Query: 590 TYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPCFGAK 649 T C+ E D A EE I SWFW EA NS S+ DK E I Sbjct: 97 TSSTCKNEAGTDAWFWAGEEATI-NSWFWNGEEA-----GNSFSTKNDKPE--IGAQVCA 148 Query: 650 EEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRPEEEEDIVNSWFW 709 EE ++ G C+ +GAEE EEEE+++ +WFW Sbjct: 149 EE--LEPAAGADCKPRSGAEE---------------------------EEEENVIGNWFW 179 Score = 37.4 bits (85), Expect = 0.10 Identities = 56/220 (25%), Positives = 81/220 (36%), Gaps = 35/220 (15%) Query: 1 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMP 60 M G + ++ AQ K EKK + GA E + VVRP +T+A+ A+ K SK Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGA--EREATGVVRPVAKTRAK----AKAKTGSKTDA 54 Query: 61 GASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASP 120 A K + A K A + P + K P+ G E S T +N Sbjct: 55 VAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDF--TPKAGNESTSSTCKNE-------- 104 Query: 121 LVSTDSVLVAK-----TKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSW 175 TD+ A + E N SF + + G Q E G+ Sbjct: 105 -AGTDAWFWAGEEATINSWFWNGEEAGN----SFSTKNDKPEIGAQVCAEELEPA-AGAD 158 Query: 176 CCPRPTSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHP 215 C PR +++E N W FW GD+ + +P Sbjct: 159 CKPRSGAEEEEEENVIGNW--------FWEGDDTSFDPNP 190 >gi|41054846 armadillo repeat containing, X-linked 5 [Homo sapiens] Length = 558 Score = 197 bits (500), Expect = 8e-50 Identities = 133/461 (28%), Positives = 242/461 (52%), Gaps = 35/461 (7%) Query: 943 SRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVD--NRTDNG--SNCGSRTLADED 998 S+ + TV E K A + S+ ++ D+ + +R D ++ G ++ +DED Sbjct: 108 SKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKS-SDED 166 Query: 999 EAIVGSWFWAGDEAHFESNPSPVFRA---ICRSTCSVEQEPDPSRRPQSWEEVTVQFKPG 1055 E + SWFW G+E S P + + ++++P P+ +P +T++ K Sbjct: 167 EENICSWFWTGEEPSVGSWFWPEEETSLQVYKPLPKIQEKPKPTHKPT----LTIKQKVI 222 Query: 1056 PWGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQ--ESLLQPD---QPSPE 1110 W R + + P GG+ L PEG E+L++ +P + Sbjct: 223 AWSRARYIVLVPVE-------------GGEQS---LPPEGNWTLVETLIETPLGIRPLTK 266 Query: 1111 FPFQYDPSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPF 1170 P + P Y+++ EI++ +R +E P +C+C + +EF++L+ L++ +DPF Sbjct: 267 IPPYHGPYYQTLAEIKKQIRQREKYGPNPKACHCKSRGFSLEPKEFDKLVALLKLTKDPF 326 Query: 1171 IHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNL 1230 IHEI+ + MG+ A FT+D I D G+ +IE L+N P+ + L + + Sbjct: 327 IHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNVKEHPGALSMVDDSSESSEEP 386 Query: 1231 NIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNA 1290 ++YI +VC+ ++ ++SP QL+G++++ HL+ + H ++ +Y+ FL+LL G+ Sbjct: 387 KSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKFEDHYVITSYIPDFLTLLNKGSV 446 Query: 1291 KTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIK 1350 KT+F+VLK+ LS+N T+EL+SA+ +S + FN+ E+ NI ++ IFENI K Sbjct: 447 KTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFK 506 Query: 1351 -KETVFSDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPE 1390 K +F+ + F LIS F + ++F ++LQ ++ +DPE Sbjct: 507 TKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEH-SDPE 546 Score = 44.3 bits (103), Expect = 8e-04 Identities = 41/145 (28%), Positives = 61/145 (42%), Gaps = 24/145 (16%) Query: 319 SKMRAGKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKE---- 374 ++ +AG A R REA M + +VIK E T ++P+ ++ Sbjct: 50 TQAKAGDGAMTRTHTVTYREA----MAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQ 105 Query: 375 --------ARARAMTKEEAKTKA--RARAKQEARSEEEALIGTWFWATDESSMADEASIE 424 +R +TK E K A A + A+S ++A G+ +E SI Sbjct: 106 TKSKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSHDKANTGS------RPDRREETSIG 159 Query: 425 SSLQVEDESIIGSWFWTEEEASMGT 449 EDE I SWFWT EE S+G+ Sbjct: 160 MKSSDEDEENICSWFWTGEEPSVGS 184 Score = 42.4 bits (98), Expect = 0.003 Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 24/86 (27%) Query: 823 RREAGSCSKSSPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGSWFWPE 882 RRE S S +EE + SWFW E E +VGSWFWPE Sbjct: 152 RREETSIGMKSSDEDEENIC--SWFWTGE--------------------EPSVGSWFWPE 189 Query: 883 EEASIQAGS--QAVEEMESETEEETI 906 EE S+Q ++E T + T+ Sbjct: 190 EETSLQVYKPLPKIQEKPKPTHKPTL 215 Score = 42.0 bits (97), Expect = 0.004 Identities = 54/233 (23%), Positives = 90/233 (38%), Gaps = 53/233 (22%) Query: 311 AGKEAKFRSKMRAGKE------ANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENAN 364 +G EA+ R K AG + A R + + EA + +K ES + Sbjct: 4 SGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAE------LKTESVTQAKAGDG 57 Query: 365 TFSRPMIKKEARARAMTKE------EAKTKARARAKQEARSEEEALIGTWFWATDESSMA 418 +R A A+T+E KT+ K + +E + T A S ++ Sbjct: 58 AMTRTHTVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVS 117 Query: 419 DEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGERIGDSLFGAREKTSMK 478 E + E+ I S+ + ++A+ G SRP RE+TS+ Sbjct: 118 TVTKSEVKVVAVIEANIRSYAKSHDKANTG------SRP------------DRREETSI- 158 Query: 479 TGAEATSESILAADDEQVIIGSWFWAGEEVNQEAEEETIFGSWFWVIDAASVE 531 + ++D+++ I SWFW GEE + GSWFW + S++ Sbjct: 159 --------GMKSSDEDEENICSWFWTGEEPS--------VGSWFWPEEETSLQ 195 Score = 40.8 bits (94), Expect = 0.009 Identities = 43/196 (21%), Positives = 82/196 (41%), Gaps = 15/196 (7%) Query: 86 SRFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTD 145 +R + +A+ Q ++ +Q +A + T+SV AK + D + T Sbjct: 8 ARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAK----AGDGAMTRTH 63 Query: 146 TESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDKS-VSSLFW 204 T ++ A + + +K + + +P +++ P + K + S VS++ Sbjct: 64 TVTYREAMAVTREVIKVEDTTKTRVMVETKT--KPLAERSIVPQTKSKAMPMSRVSTVTK 121 Query: 205 SGDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFW 264 S +V A ++ + RS ++ +ANT SR +E I S EDE WFW Sbjct: 122 SEVKVVAV------IEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFW 175 Query: 265 ARDK--TNTWSGPRED 278 ++ +W P E+ Sbjct: 176 TGEEPSVGSWFWPEEE 191 Score = 37.0 bits (84), Expect = 0.13 Identities = 18/39 (46%), Positives = 24/39 (61%), Gaps = 5/39 (12%) Query: 694 KSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNI 732 KS E+EE+I SWFW T E +GSW W EE+++ Sbjct: 161 KSSDEDEENIC-SWFW----TGEEPSVGSWFWPEEETSL 194 Score = 35.4 bits (80), Expect = 0.39 Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 22/60 (36%) Query: 531 ESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAENQT 590 E+ +G+ ++ E+EE I WFW+GE+ + GSWFW E +T Sbjct: 155 ETSIGM----KSSDEDEENICSWFWTGEEPSV------------------GSWFWPEEET 192 Score = 32.0 bits (71), Expect = 4.3 Identities = 28/93 (30%), Positives = 37/93 (39%), Gaps = 26/93 (27%) Query: 735 TGEKAKLLTEEETIINSWFWKEDEAI--SEATDREES----RPEAEEGDIIGSWFWAGEE 788 T + K++ E I S+ D+A S REE+ + E+ + I SWFW GEE Sbjct: 120 TKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEE 179 Query: 789 DRLEPAAETREEDRLAAEKEGIVGSWFGAREET 821 VGSWF EET Sbjct: 180 PS--------------------VGSWFWPEEET 192 >gi|29540566 armadillo repeat containing, X-linked 3 [Homo sapiens] Length = 379 Score = 137 bits (345), Expect = 7e-32 Identities = 73/202 (36%), Positives = 122/202 (60%) Query: 1151 IGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 1210 + +E +++L L+E P+I E + IA+G +A F RD IRD G + ++ +LN Sbjct: 118 LSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDP 177 Query: 1211 RVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDY 1270 V+ L + ++ N ++ Y+ +VC++T+ ++S QL+G+R++ ++T T +Y Sbjct: 178 IVKEKALIVLNNLSVNAENQRRLKVYMNQVCDDTITSRLNSSVQLAGLRLLTNMTVTNEY 237 Query: 1271 HTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREE 1330 ++AN +S F L + GN +T+ VLK+LLNL+EN MT+ELL A+ S LFN++E Sbjct: 238 QHMLANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNKKE 297 Query: 1331 TNDNIQIVLAIFENIGNNIKKE 1352 + I +L IFENI +N K E Sbjct: 298 NKEVILKLLVIFENINDNFKWE 319 >gi|29540564 armadillo repeat containing, X-linked 3 [Homo sapiens] Length = 379 Score = 137 bits (345), Expect = 7e-32 Identities = 73/202 (36%), Positives = 122/202 (60%) Query: 1151 IGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 1210 + +E +++L L+E P+I E + IA+G +A F RD IRD G + ++ +LN Sbjct: 118 LSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDP 177 Query: 1211 RVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDY 1270 V+ L + ++ N ++ Y+ +VC++T+ ++S QL+G+R++ ++T T +Y Sbjct: 178 IVKEKALIVLNNLSVNAENQRRLKVYMNQVCDDTITSRLNSSVQLAGLRLLTNMTVTNEY 237 Query: 1271 HTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREE 1330 ++AN +S F L + GN +T+ VLK+LLNL+EN MT+ELL A+ S LFN++E Sbjct: 238 QHMLANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNKKE 297 Query: 1331 TNDNIQIVLAIFENIGNNIKKE 1352 + I +L IFENI +N K E Sbjct: 298 NKEVILKLLVIFENINDNFKWE 319 >gi|7705274 armadillo repeat containing, X-linked 3 [Homo sapiens] Length = 379 Score = 137 bits (345), Expect = 7e-32 Identities = 73/202 (36%), Positives = 122/202 (60%) Query: 1151 IGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 1210 + +E +++L L+E P+I E + IA+G +A F RD IRD G + ++ +LN Sbjct: 118 LSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDP 177 Query: 1211 RVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDY 1270 V+ L + ++ N ++ Y+ +VC++T+ ++S QL+G+R++ ++T T +Y Sbjct: 178 IVKEKALIVLNNLSVNAENQRRLKVYMNQVCDDTITSRLNSSVQLAGLRLLTNMTVTNEY 237 Query: 1271 HTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREE 1330 ++AN +S F L + GN +T+ VLK+LLNL+EN MT+ELL A+ S LFN++E Sbjct: 238 QHMLANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNKKE 297 Query: 1331 TNDNIQIVLAIFENIGNNIKKE 1352 + I +L IFENI +N K E Sbjct: 298 NKEVILKLLVIFENINDNFKWE 319 >gi|7706143 armadillo repeat containing, X-linked 1 [Homo sapiens] Length = 453 Score = 134 bits (338), Expect = 5e-31 Identities = 73/239 (30%), Positives = 135/239 (56%), Gaps = 2/239 (0%) Query: 1151 IGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 1210 + + + +++L ++E+ DPFI E++ + +G +A F ++ IR+ G V +I L+ Sbjct: 202 LSAPDLQKVLNILERTNDPFIQEVALVTLGNNAAYSFNQNAIRELGGVPIIAKLIKTKDP 261 Query: 1211 RVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDY 1270 +R + ++ N I+TYI +VC++T+ +DS Q++G+R++ ++T T Y Sbjct: 262 IIREKTYNALNNLSVNAENQGKIKTYISQVCDDTMVCRLDSAVQMAGLRLLTNMTVTNHY 321 Query: 1271 HTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREE 1330 L++ F +LL GN T+ ++K+++N +EN MT+EL+S + SE I LFN+E Sbjct: 322 QHLLSYSFPDFFALLFLGNHFTKIQIMKLIINFTENPAMTRELVSCKVPSELISLFNKEW 381 Query: 1331 TNDNIQIVLAIFENIGNNIKKETVFSD-DDFNIEPLISAFHKVEKFAKELQGKTDNQND 1388 + + +L +FENI +NIK E + S +F+ L F + K+++ N ND Sbjct: 382 DREILLNILTLFENINDNIKNEGLASSRKEFSRSSLFFLFKESGVCVKKIKALA-NHND 439 >gi|238776793 SVH protein isoform b [Homo sapiens] Length = 308 Score = 120 bits (302), Expect = 7e-27 Identities = 63/202 (31%), Positives = 116/202 (57%) Query: 1151 IGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 1210 + +E+ ++LL L+E DP I E + I +G +A + IR+ G + ++ +N+ + Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117 Query: 1211 RVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDY 1270 ++ L + ++ N I+ YI +VCE+ + ++S QL+G+ ++ ++T T D+ Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDH 177 Query: 1271 HTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREE 1330 ++ +Y++ +L TGN T+ VLK+LLNLSEN MT+ LL A+ S F+ L++ Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTKVQVLKLLLNLSENPAMTEGLLRAQVDSSFLSLYDSHV 237 Query: 1331 TNDNIQIVLAIFENIGNNIKKE 1352 + + VL +F+NI N +K E Sbjct: 238 AKEILLRVLTLFQNIKNCLKIE 259 >gi|31377663 SVH protein isoform a [Homo sapiens] Length = 343 Score = 120 bits (302), Expect = 7e-27 Identities = 63/202 (31%), Positives = 116/202 (57%) Query: 1151 IGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 1210 + +E+ ++LL L+E DP I E + I +G +A + IR+ G + ++ +N+ + Sbjct: 93 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 152 Query: 1211 RVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDY 1270 ++ L + ++ N I+ YI +VCE+ + ++S QL+G+ ++ ++T T D+ Sbjct: 153 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDH 212 Query: 1271 HTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREE 1330 ++ +Y++ +L TGN T+ VLK+LLNLSEN MT+ LL A+ S F+ L++ Sbjct: 213 QHMLHSYITDLFQVLLTGNGNTKVQVLKLLLNLSENPAMTEGLLRAQVDSSFLSLYDSHV 272 Query: 1331 TNDNIQIVLAIFENIGNNIKKE 1352 + + VL +F+NI N +K E Sbjct: 273 AKEILLRVLTLFQNIKNCLKIE 294 >gi|7662162 ALEX2 protein [Homo sapiens] Length = 632 Score = 111 bits (277), Expect = 6e-24 Identities = 60/211 (28%), Positives = 117/211 (55%), Gaps = 1/211 (0%) Query: 1151 IGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 1210 +G + ++L L++K DPFI +++ + + + ++ IR G + +I ++N Sbjct: 383 LGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDP 442 Query: 1211 RVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDY 1270 ++ L M ++ Y N +Q Y+ KV ++ +A +++S Q+ G++ + ++T T DY Sbjct: 443 HIKEKALMAMNNLSENYENQGRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDY 502 Query: 1271 HTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREE 1330 L+ N ++ F LL+ G K + +LK+L N +EN M K+LLS + + F L+N Sbjct: 503 QHLLVNSIANFFRLLSQGGGKIKVEILKILSNFAENPDMLKKLLSTQVPASFSSLYNSYV 562 Query: 1331 TNDNIQIVLAIFENIGNNIKKETVFSDDDFN 1361 ++ + L +FE I +N++ E VF+ +FN Sbjct: 563 ESEILINALTLFEIIYDNLRAE-VFNYREFN 592 >gi|29540562 ALEX2 protein [Homo sapiens] Length = 632 Score = 111 bits (277), Expect = 6e-24 Identities = 60/211 (28%), Positives = 117/211 (55%), Gaps = 1/211 (0%) Query: 1151 IGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 1210 +G + ++L L++K DPFI +++ + + + ++ IR G + +I ++N Sbjct: 383 LGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDP 442 Query: 1211 RVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDY 1270 ++ L M ++ Y N +Q Y+ KV ++ +A +++S Q+ G++ + ++T T DY Sbjct: 443 HIKEKALMAMNNLSENYENQGRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDY 502 Query: 1271 HTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREE 1330 L+ N ++ F LL+ G K + +LK+L N +EN M K+LLS + + F L+N Sbjct: 503 QHLLVNSIANFFRLLSQGGGKIKVEILKILSNFAENPDMLKKLLSTQVPASFSSLYNSYV 562 Query: 1331 TNDNIQIVLAIFENIGNNIKKETVFSDDDFN 1361 ++ + L +FE I +N++ E VF+ +FN Sbjct: 563 ESEILINALTLFEIIYDNLRAE-VFNYREFN 592 >gi|169165522 PREDICTED: similar to SVH protein isoform 1 [Homo sapiens] Length = 284 Score = 85.5 bits (210), Expect = 3e-16 Identities = 49/202 (24%), Positives = 99/202 (49%), Gaps = 24/202 (11%) Query: 1151 IGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 1210 + +E+ ++LL L+E DP I E + I +G +A + IR+ G + ++ +N+ + Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117 Query: 1211 RVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDY 1270 ++ L + ++ N I+ YI +VCE+ + ++S QL+G+R++ ++T T D+ Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLRLLTNMTVTNDH 177 Query: 1271 HTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREE 1330 ++ +Y++ +L TGN T+ S F+ L++ Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTKVD------------------------SSFLSLYDSHV 213 Query: 1331 TNDNIQIVLAIFENIGNNIKKE 1352 + + VL +F+NI N +K E Sbjct: 214 AKEILLRVLTLFQNIKNCLKIE 235 >gi|169165931 PREDICTED: similar to SVH protein isoform 1 [Homo sapiens] Length = 284 Score = 83.6 bits (205), Expect = 1e-15 Identities = 48/202 (23%), Positives = 99/202 (49%), Gaps = 24/202 (11%) Query: 1151 IGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 1210 + +E+ ++LL L+E DP I E + I +G +A + IR+ G + ++ +N+ + Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117 Query: 1211 RVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDY 1270 ++ L + ++ N I+ YI +VCE+ + ++S QL+G+R++ ++T T D+ Sbjct: 118 SIKDKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLRLLTNMTVTNDH 177 Query: 1271 HTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREE 1330 ++ +Y++ +L TGN T+ S F+ L++ Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTKVD------------------------SSFLSLYDSHV 213 Query: 1331 TNDNIQIVLAIFENIGNNIKKE 1352 + + VL +F++I N +K E Sbjct: 214 AKEILLRVLTLFQHIKNCLKIE 235 >gi|113414573 PREDICTED: similar to SVH protein isoform 2 [Homo sapiens] Length = 284 Score = 83.6 bits (205), Expect = 1e-15 Identities = 48/202 (23%), Positives = 99/202 (49%), Gaps = 24/202 (11%) Query: 1151 IGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 1210 + +E+ ++LL L+E DP I E + I +G +A + IR+ G + ++ +N+ + Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117 Query: 1211 RVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDY 1270 ++ L + ++ N I+ YI +VCE+ + ++S QL+G+R++ ++T T D+ Sbjct: 118 SIKDKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLRLLTNMTVTNDH 177 Query: 1271 HTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREE 1330 ++ +Y++ +L TGN T+ S F+ L++ Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTKVD------------------------SSFLSLYDSHV 213 Query: 1331 TNDNIQIVLAIFENIGNNIKKE 1352 + + VL +F++I N +K E Sbjct: 214 AKEILLRVLTLFQHIKNCLKIE 235 >gi|238776797 SVH protein isoform e [Homo sapiens] Length = 284 Score = 83.2 bits (204), Expect = 2e-15 Identities = 48/202 (23%), Positives = 98/202 (48%), Gaps = 24/202 (11%) Query: 1151 IGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 1210 + +E+ ++LL L+E DP I E + I +G +A + IR+ G + ++ +N+ + Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117 Query: 1211 RVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDY 1270 ++ L + ++ N I+ YI +VCE+ + ++S QL+G+ ++ ++T T D+ Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDH 177 Query: 1271 HTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREE 1330 ++ +Y++ +L TGN T+ S F+ L++ Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTKVD------------------------SSFLSLYDSHV 213 Query: 1331 TNDNIQIVLAIFENIGNNIKKE 1352 + + VL +F+NI N +K E Sbjct: 214 AKEILLRVLTLFQNIKNCLKIE 235 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 53.9 bits (128), Expect = 1e-06 Identities = 83/298 (27%), Positives = 110/298 (36%), Gaps = 33/298 (11%) Query: 728 EESNIDGTGEKAKLLTEEE--TIINSWFWKEDEAISEATDREESRPEAEEGDIIGSWFWA 785 EE +G GE+ + E E + +E+E + EE E EEG+ Sbjct: 797 EEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGE-------- 848 Query: 786 GEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREETIRREAGSCSKSSPKAEEEEVIIGS 845 GEE+ E E E+ E+EG G G EE E + + EEEE G Sbjct: 849 GEEEEGEGKGEEEGEEG-EGEEEGEEGEGEGEEEEG---EGEGEEEGEGEGEEEE---GE 901 Query: 846 WFWEEEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQA----GSQAVEEMESET 901 EEE E E G EEE G EEE + G EE E E Sbjct: 902 GEGEEEGEGEGEE----EEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEG 957 Query: 902 EEETIFGSWFWDGK--------EVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGT 953 EEE G +G+ E EE G + E +EE E + E Sbjct: 958 EEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEE 1017 Query: 954 VATCESKPENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLADEDEAIVGSWFWAGDE 1011 E + E EEG G E E+E + R G +R +E+E G + G+E Sbjct: 1018 EGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEE 1075 Score = 39.7 bits (91), Expect = 0.020 Identities = 80/323 (24%), Positives = 113/323 (34%), Gaps = 29/323 (8%) Query: 382 KEEAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWT 441 KEE + K RA +E + EEE G +E + E +VE + Sbjct: 770 KEEGERKKEERAGKEEKGEEEGDQGE---GEEEETEGRGEEKEEGGEVEGGEVEEGKGER 826 Query: 442 EEEASMGTGASSKSR-PRTDGERIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGS 500 EEE G G + +GE + G E+ + E E +E+ G Sbjct: 827 EEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGE 886 Query: 501 WFWAGEEVNQEAEEETIFGSWFWVIDAASVESGVGVSCESRTRSEEEEVIGPWFWSGEQV 560 GE +E E E + G G E + EEE G GE+ Sbjct: 887 GEEEGEGEGEEEEGEG---------EGEEEGEGEGEEEEGEGKGEEEGEEGE--GEGEEE 935 Query: 561 DIEAGIGEEARPGAEEETIFGSWFWAENQTYMDCRAETSCDTMQGAEEEEPIIGSWFWTR 620 + E G GE+ EEE G W E + + E + +G E E G Sbjct: 936 EGE-GEGEDGEGEGEEEE--GEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEE 992 Query: 621 VEACVEGDVNSKSSLEDKEEAMIPCFGAKE-EVSMKHGTGVRCRFMAGAEETNNKSCFWA 679 E EG+ + E + E G E EV + G G G EE + Sbjct: 993 EEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEG------EGEEEEGEEEGEER 1046 Query: 680 EKEPCMYPAGGGSWKSRPEEEED 702 EKE G + ++R EEEE+ Sbjct: 1047 EKE----GEGEENRRNREEEEEE 1065 Score = 38.5 bits (88), Expect = 0.046 Identities = 68/269 (25%), Positives = 95/269 (35%), Gaps = 25/269 (9%) Query: 743 TEEETIINSWFWKEDEAISEATDR---EESRPEAEEGDIIGSWFWA---GEEDRLEPAAE 796 T EE + W+++E D+ E RP E ++ W GEE + + Sbjct: 658 TCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQ 717 Query: 797 TREEDRLAAEKEGIVGSWFGAREETIRREAGSCSKSSPKAEEEEVIIGSWFWEEEASPEA 856 +++R +EG EE RE + K E E + +EE + Sbjct: 718 GHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKK 777 Query: 857 VAGVGFESK------PGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGSW 910 G E K G EEE T G EE ++ G VEE + E EEE G Sbjct: 778 EERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGE--VEEGKGEREEEEEEGEG 835 Query: 911 FWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEGAIVG 970 + E EE G + E+ E E + E G E + E EEG G Sbjct: 836 EEEEGEGEEEEGE---GEEEEGEGKGEEEGEEGEGEEEGEEG-----EGEGEEEEGEGEG 887 Query: 971 SWFEAEDEVDNRTDNGSNCGSRTLADEDE 999 E E E + + G G E E Sbjct: 888 ---EEEGEGEGEEEEGEGEGEEEGEGEGE 913 >gi|169165524 PREDICTED: similar to SVH protein isoform 2 [Homo sapiens] Length = 253 Score = 52.4 bits (124), Expect = 3e-06 Identities = 40/157 (25%), Positives = 75/157 (47%), Gaps = 17/157 (10%) Query: 1151 IGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 1210 + +E+ ++LL L+E DP I E + I +G +A + IR+ G + ++ +N+ + Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117 Query: 1211 RVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDY 1270 ++ L + ++ N I+ YI +VCE+ + ++S L+G + T D Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVLLTG-----NGNTKVD- 171 Query: 1271 HTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENL 1307 S FLSL + AK +L +L L +N+ Sbjct: 172 --------SSFLSLYDSHVAK---EILLRVLTLFQNI 197 >gi|238776799 SVH protein isoform d [Homo sapiens] Length = 249 Score = 51.6 bits (122), Expect = 5e-06 Identities = 29/71 (40%), Positives = 42/71 (59%) Query: 1282 LSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAI 1341 LS+ K + VLK+LLNLSEN MT+ LL A+ S F+ L++ + + VL + Sbjct: 130 LSVNVENQIKIKVQVLKLLLNLSENPAMTEGLLRAQVDSSFLSLYDSHVAKEILLRVLTL 189 Query: 1342 FENIGNNIKKE 1352 F+NI N +K E Sbjct: 190 FQNIKNCLKIE 200 Score = 41.2 bits (95), Expect = 0.007 Identities = 36/157 (22%), Positives = 69/157 (43%), Gaps = 21/157 (13%) Query: 1151 IGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 1210 + +E+ ++LL L+E DP I E + I +G +A + IR+ G + ++ +N+ + Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117 Query: 1211 RVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDY 1270 ++ L + ++ N I+ + K+ L ++P G+ Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKVQVLKL----LLNLSENPAMTEGL------------ 161 Query: 1271 HTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENL 1307 L A S FLSL + AK +L +L L +N+ Sbjct: 162 --LRAQVDSSFLSLYDSHVAK---EILLRVLTLFQNI 193 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.127 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 57,018,906 Number of Sequences: 37866 Number of extensions: 2849621 Number of successful extensions: 9548 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 49 Number of HSP's successfully gapped in prelim test: 141 Number of HSP's that attempted gapping in prelim test: 7033 Number of HSP's gapped (non-prelim): 773 length of query: 1395 length of database: 18,247,518 effective HSP length: 115 effective length of query: 1280 effective length of database: 13,892,928 effective search space: 17782947840 effective search space used: 17782947840 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.