Search of human proteins with 186910308

Search of human proteins with 186910308

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|186910308 solute carrier family 7 member 7 [Homo sapiens]
         (511 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|186910308 solute carrier family 7 member 7 [Homo sapiens]         1013   0.0  
gi|186910306 solute carrier family 7 member 7 [Homo sapiens]         1013   0.0  
gi|186910304 solute carrier family 7 member 7 [Homo sapiens]         1013   0.0  
gi|115648063 solute carrier family 7 (cationic amino acid transp...   759   0.0  
gi|115648022 solute carrier family 7 (cationic amino acid transp...   759   0.0  
gi|33286428 solute carrier family 7 (cationic amino acid transpo...   478   e-135
gi|71979932 solute carrier family 7 (cationic amino acid transpo...   475   e-134
gi|7657683 solute carrier family 7, (cationic amino acid transpo...   443   e-124
gi|9790235 solute carrier family 7, member 10 [Homo sapiens]          430   e-120
gi|187423910 solute carrier family 7, member 9 [Homo sapiens]         410   e-114
gi|7657591 solute carrier family 7, member 9 [Homo sapiens]           410   e-114
gi|33286430 solute carrier family 7 (cationic amino acid transpo...   266   4e-71
gi|71999149 solute carrier family 7, (cationic amino acid transp...   246   3e-65
gi|110347453 solute carrier family 7 (cationic amino acid transp...   101   1e-21
gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s...    92   9e-19
gi|4507047 solute carrier family 7 (cationic amino acid transpor...    90   4e-18
gi|114326550 solute carrier family 7 (cationic amino acid transp...    90   4e-18
gi|114326544 solute carrier family 7 (cationic amino acid transp...    90   4e-18
gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo s...    89   7e-18
gi|181337167 solute carrier family 7 (cationic amino acid transp...    74   3e-13
gi|198041678 solute carrier family 12 (potassium-chloride transp...    33   0.47 
gi|11968148 solute carrier family 12 (potassium-chloride transpo...    33   0.47 
gi|34916028 solute carrier family 16 (monocarboxylic acid transp...    32   1.8  
gi|219689113 two pore segment channel 1 isoform 1 [Homo sapiens]       31   3.1  
gi|29725622 two pore segment channel 1 isoform 2 [Homo sapiens]        31   3.1  
gi|41352721 solute carrier family 36 member 1 [Homo sapiens]           30   4.0  
gi|4759114 solute carrier family 16, member 4 [Homo sapiens]           30   4.0  
gi|36951034 G protein-coupled receptor 78 [Homo sapiens]               30   4.0  
gi|166235895 ectonucleoside triphosphate diphosphohydrolase 6 is...    30   4.0  
gi|166235893 ectonucleoside triphosphate diphosphohydrolase 6 is...    30   4.0  

>gi|186910308 solute carrier family 7 member 7 [Homo sapiens]
          Length = 511

 Score = 1013 bits (2618), Expect = 0.0
 Identities = 511/511 (100%), Positives = 511/511 (100%)

Query: 1   MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPK 60
           MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPK
Sbjct: 1   MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPK 60

Query: 61  GVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRL 120
           GVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRL
Sbjct: 61  GVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRL 120

Query: 121 WTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWG 180
           WTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWG
Sbjct: 121 WTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWG 180

Query: 181 TLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYS 240
           TLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYS
Sbjct: 181 TLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYS 240

Query: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300
           GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF
Sbjct: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300

Query: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360
           ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP
Sbjct: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360

Query: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420
           SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF
Sbjct: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420

Query: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480
           PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT
Sbjct: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480

Query: 481 RYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN 511
           RYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN
Sbjct: 481 RYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN 511


>gi|186910306 solute carrier family 7 member 7 [Homo sapiens]
          Length = 511

 Score = 1013 bits (2618), Expect = 0.0
 Identities = 511/511 (100%), Positives = 511/511 (100%)

Query: 1   MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPK 60
           MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPK
Sbjct: 1   MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPK 60

Query: 61  GVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRL 120
           GVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRL
Sbjct: 61  GVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRL 120

Query: 121 WTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWG 180
           WTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWG
Sbjct: 121 WTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWG 180

Query: 181 TLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYS 240
           TLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYS
Sbjct: 181 TLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYS 240

Query: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300
           GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF
Sbjct: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300

Query: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360
           ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP
Sbjct: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360

Query: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420
           SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF
Sbjct: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420

Query: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480
           PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT
Sbjct: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480

Query: 481 RYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN 511
           RYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN
Sbjct: 481 RYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN 511


>gi|186910304 solute carrier family 7 member 7 [Homo sapiens]
          Length = 511

 Score = 1013 bits (2618), Expect = 0.0
 Identities = 511/511 (100%), Positives = 511/511 (100%)

Query: 1   MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPK 60
           MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPK
Sbjct: 1   MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPK 60

Query: 61  GVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRL 120
           GVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRL
Sbjct: 61  GVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRL 120

Query: 121 WTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWG 180
           WTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWG
Sbjct: 121 WTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWG 180

Query: 181 TLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYS 240
           TLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYS
Sbjct: 181 TLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYS 240

Query: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300
           GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF
Sbjct: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300

Query: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360
           ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP
Sbjct: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360

Query: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420
           SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF
Sbjct: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420

Query: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480
           PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT
Sbjct: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480

Query: 481 RYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN 511
           RYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN
Sbjct: 481 RYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN 511


>gi|115648063 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 6 [Homo sapiens]
          Length = 515

 Score =  759 bits (1959), Expect = 0.0
 Identities = 368/500 (73%), Positives = 439/500 (87%), Gaps = 7/500 (1%)

Query: 11  SQPEVETSPLGDGASP---GPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSA 67
           SQ +VE     D +SP     E ++LKKEISLLNGV L+VGNMIGSGIFVSPKGVL+++A
Sbjct: 20  SQSQVEE----DVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTA 75

Query: 68  SFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLII 127
           S+G+SL++WA+GGLFSV GALCYAELGTTI KSGASYAYILEAFGGF+AFIRLW SLL++
Sbjct: 76  SYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVV 135

Query: 128 EPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIF 187
           EPT QAIIAITFANY++QP FPSC  PY A RLLAAACICLLTF+NCAYVKWGT VQD F
Sbjct: 136 EPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTF 195

Query: 188 TYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNY 247
           TYAKV+ALIA+IV G+V+L QG S HF+++FEGSS+ +G+++LALYSALFSYSGWDTLN+
Sbjct: 196 TYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNF 255

Query: 248 VTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGI 307
           VTEEIKNPERNLPL+IGISMPIVT+IYILTNVAYYTVL++ D+L+SDAVAVTFADQ FG+
Sbjct: 256 VTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGM 315

Query: 308 FNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGI 367
           F+W IP++VALSCFGGLNASI A+SRLFFVGSREGHLPD + MIH+ERFTP+P+LLFN  
Sbjct: 316 FSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCT 375

Query: 368 MALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLC 427
           MALIYL VED+FQLINY+SFSYWFFVGLS+VGQLYLRWKEP RPRPLKLSVFFPIVFC+C
Sbjct: 376 MALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCIC 435

Query: 428 TIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLC 487
           ++FLV VPL++DTINSLIGI IALSG+PFYF+ + +PE +RPL++R ++ + TR  Q LC
Sbjct: 436 SVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLC 495

Query: 488 MSVAAEMDLEDGGEMPKQRD 507
             V  E+D+ +  +  ++ D
Sbjct: 496 FCVLTELDVAEEKKDERKTD 515


>gi|115648022 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 6 [Homo sapiens]
          Length = 515

 Score =  759 bits (1959), Expect = 0.0
 Identities = 368/500 (73%), Positives = 439/500 (87%), Gaps = 7/500 (1%)

Query: 11  SQPEVETSPLGDGASP---GPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSA 67
           SQ +VE     D +SP     E ++LKKEISLLNGV L+VGNMIGSGIFVSPKGVL+++A
Sbjct: 20  SQSQVEE----DVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTA 75

Query: 68  SFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLII 127
           S+G+SL++WA+GGLFSV GALCYAELGTTI KSGASYAYILEAFGGF+AFIRLW SLL++
Sbjct: 76  SYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVV 135

Query: 128 EPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIF 187
           EPT QAIIAITFANY++QP FPSC  PY A RLLAAACICLLTF+NCAYVKWGT VQD F
Sbjct: 136 EPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTF 195

Query: 188 TYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNY 247
           TYAKV+ALIA+IV G+V+L QG S HF+++FEGSS+ +G+++LALYSALFSYSGWDTLN+
Sbjct: 196 TYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNF 255

Query: 248 VTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGI 307
           VTEEIKNPERNLPL+IGISMPIVT+IYILTNVAYYTVL++ D+L+SDAVAVTFADQ FG+
Sbjct: 256 VTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGM 315

Query: 308 FNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGI 367
           F+W IP++VALSCFGGLNASI A+SRLFFVGSREGHLPD + MIH+ERFTP+P+LLFN  
Sbjct: 316 FSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCT 375

Query: 368 MALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLC 427
           MALIYL VED+FQLINY+SFSYWFFVGLS+VGQLYLRWKEP RPRPLKLSVFFPIVFC+C
Sbjct: 376 MALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCIC 435

Query: 428 TIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLC 487
           ++FLV VPL++DTINSLIGI IALSG+PFYF+ + +PE +RPL++R ++ + TR  Q LC
Sbjct: 436 SVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLC 495

Query: 488 MSVAAEMDLEDGGEMPKQRD 507
             V  E+D+ +  +  ++ D
Sbjct: 496 FCVLTELDVAEEKKDERKTD 515


>gi|33286428 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 8 isoform a [Homo
           sapiens]
          Length = 535

 Score =  478 bits (1230), Expect = e-135
 Identities = 246/514 (47%), Positives = 348/514 (67%), Gaps = 13/514 (2%)

Query: 3   DSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGV 62
           ++TE +     E + SP    A  G   V LKKEI L++   +IVGN+IGSGIFVSPKGV
Sbjct: 9   NNTEKKHPGGGESDASP---EAGSGGGGVALKKEIGLVSACGIIVGNIIGSGIFVSPKGV 65

Query: 63  LIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWT 122
           L  + S GL+L++W V G  +V GALCYAELG TI KSG  Y+Y+ + FGG   F+RLW 
Sbjct: 66  LENAGSVGLALIVWIVTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWI 125

Query: 123 SLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTL 182
           ++L+I PT+QA+IA+TF+NY++QPLFP+CF P +  RLLAA C+ LLT++NC+ V+W T 
Sbjct: 126 AVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATR 185

Query: 183 VQDIFTYAKVLALIAVIVAGIVRLGQGASTHFE--NSFEGSSFA-VGDIALALYSALFSY 239
           VQDIFT  K+LAL  +I+ GIV++ +G     E  N+FE      +G +ALA     F+Y
Sbjct: 186 VQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAY 245

Query: 240 SGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVT 299
            GW+ LNYVTEE+ +P +NLP +I IS+P+VT +Y+  NVAY T +  +++LAS+AVAVT
Sbjct: 246 GGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVT 305

Query: 300 FADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPV 359
           F +++ G+  WI+P+SVALS FGG+N S+  +SRLFF G+REGHLP  + MIHV+R TP+
Sbjct: 306 FGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPI 365

Query: 360 PSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVF 419
           P+LLF  I  L+ L   D++ LINY  F  + F G+++ GQ+ LRWK+PD PRP+K+++ 
Sbjct: 366 PALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLL 425

Query: 420 FPIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSA 479
           FPI++ L   FL+   L+S+ +   IG+AI L+G+P YFL +   +HK P      +   
Sbjct: 426 FPIIYLLFWAFLLVFSLWSEPVVCGIGLAIMLTGVPVYFLGV-YWQHK-PKCFSDFIELL 483

Query: 480 TRYLQVLCMSVAAEMDLEDGGE-----MPKQRDP 508
           T   Q +C+ V  E++   G E     M +Q+ P
Sbjct: 484 TLVSQKMCVVVYPEVERGSGTEEANEDMEEQQQP 517


>gi|71979932 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 5 [Homo sapiens]
          Length = 507

 Score =  475 bits (1223), Expect = e-134
 Identities = 243/493 (49%), Positives = 339/493 (68%), Gaps = 9/493 (1%)

Query: 3   DSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGV 62
           ++ E  +A++    ++P G+G     E V L++ I+LLNGV +IVG +IGSGIFV+P GV
Sbjct: 21  EAREKMLAAKSADGSAPAGEG-----EGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGV 75

Query: 63  LIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWT 122
           L  + S GL+LV+WA  G+FS+ GALCYAELGTTI KSG  YAY+LE +G   AF++LW 
Sbjct: 76  LKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWI 135

Query: 123 SLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTL 182
            LLII P+SQ I+A+ FA Y+++PLFP+C  P  A++L+A  C+ LLT +NC  VK  T 
Sbjct: 136 ELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATR 195

Query: 183 VQDIFTYAKVLALIAVIVAGIVRLGQGASTHFEN--SFEGSSFAVGDIALALYSALFSYS 240
           VQD F  AK+LAL  +I+ G V++G+G  ++ +   SFEG+   VG+I LALYS LF+Y 
Sbjct: 196 VQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYG 255

Query: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300
           GW+ LN+VTEE+ NP RNLPL+I IS+PIVT++Y+LTN+AY+T L    +L+S+AVAV F
Sbjct: 256 GWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDF 315

Query: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360
            +   G+ +WIIP+ V LSCFG +N S+  +SRLFFVGSREGHLP  + MIH +  TPVP
Sbjct: 316 GNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVP 375

Query: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420
           SL+F  +M L+Y   +DIF +IN++SF  W  V L+I+G ++LR ++P+  RP+K+++  
Sbjct: 376 SLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLAL 435

Query: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480
           P+ F L  +FL+AV  +   +   IG  I LSGLP YF    V    +P +L + + S T
Sbjct: 436 PVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYF--FGVWWKNKPKWLLQGIFSTT 493

Query: 481 RYLQVLCMSVAAE 493
              Q L   V  E
Sbjct: 494 VLCQKLMQVVPQE 506


>gi|7657683 solute carrier family 7, (cationic amino acid
           transporter, y+ system) member 11 [Homo sapiens]
          Length = 501

 Score =  443 bits (1139), Expect = e-124
 Identities = 214/474 (45%), Positives = 323/474 (68%), Gaps = 2/474 (0%)

Query: 20  LGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVG 79
           LG+   PG E+V+LK++++LL GV +I+G +IG+GIF+SPKGVL  + S G+SL IW V 
Sbjct: 27  LGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTVC 86

Query: 80  GLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITF 139
           G+ S+FGAL YAELGTTIKKSG  Y YILE FG   AF+R+W  LLII P + A+I++ F
Sbjct: 87  GVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAF 146

Query: 140 ANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVI 199
             Y+++P F  C  P  A +L+ A  I ++  +N   V W   +Q   T+ K+ A++ +I
Sbjct: 147 GRYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIII 206

Query: 200 VAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNL 259
           V G+++L +G + +F+++F G   ++  + LA Y  +++Y+GW  LN+VTEE++NPE+ +
Sbjct: 207 VPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTI 266

Query: 260 PLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALS 319
           PL+I ISM IVTI Y+LTNVAY+T ++  ++L S+AVAVTF++++ G F+  +P+ VALS
Sbjct: 267 PLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALS 326

Query: 320 CFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIF 379
           CFG +N  + A SRLF+V SREGHLP+ + MIHV + TP+P+++    + +I L   D+ 
Sbjct: 327 CFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLD 386

Query: 380 QLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYSD 439
            L+N+ SF+ W F+GL++ G +YLR+K PD  RP K+ +F P +F    +F+VA+ LYSD
Sbjct: 387 SLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSD 446

Query: 440 TINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAE 493
             ++ IG  I L+G+P Y+L I     K+P + R +    TR LQ++   V  E
Sbjct: 447 PFSTGIGFVITLTGVPAYYLFI--IWDKKPRWFRIMSEKITRTLQIILEVVPEE 498


>gi|9790235 solute carrier family 7, member 10 [Homo sapiens]
          Length = 523

 Score =  430 bits (1106), Expect = e-120
 Identities = 219/508 (43%), Positives = 328/508 (64%), Gaps = 13/508 (2%)

Query: 12  QPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGL 71
           +P    SP+        E+V LKKEI LL+   +I+GN+IGSGIF+SPKGVL +S S GL
Sbjct: 15  RPAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGL 74

Query: 72  SLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTS 131
           +L +W +GG  +  G+LCYAELG  I KSG  YAY+ E FGG   F+ LW+++LI+ PTS
Sbjct: 75  ALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTS 134

Query: 132 QAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAK 191
            A+I++TF+NY++QP+FP+C  P  ASR+L+ AC+ LLT++N + V+W T +QD+FT  K
Sbjct: 135 LAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGK 194

Query: 192 VLALIAVIVAGIVRLGQGASTHFENSFEGSSFA------VGDIALALYSALFSYSGWDTL 245
           +LAL  +I  G++++ QG   HFE     ++FA      VG +ALA     F++SGW+ L
Sbjct: 195 LLALSLIIGVGLLQIFQG---HFEELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFL 251

Query: 246 NYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIF 305
           NYVTEE+ +  +NLP +I IS+P+VT +Y  TN+AY+T +  +++L+S+AVAVTF +++ 
Sbjct: 252 NYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLL 311

Query: 306 GIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFN 365
           G F+W++P+SVALS FGG+N  +   SRL F G+REGHLP  + MIHV   TP+P+LL  
Sbjct: 312 GYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVC 371

Query: 366 GIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFC 425
                + + V D + LINY SF  +   G++I+G L LRW+ P   RP+K+++  P+ + 
Sbjct: 372 CGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYL 431

Query: 426 LCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQV 485
           +   FL+     S+ +   +G+ I L+G+P +FL   V    +P  + R+  S T + Q 
Sbjct: 432 VFWAFLLVFSFISEPMVCGVGVIIILTGVPIFFL--GVFWRSKPKCVHRLTESMTHWGQE 489

Query: 486 LCMSVAAE--MDLEDGGEMPKQRDPKSN 511
           LC  V  +   + E+ G  P    P ++
Sbjct: 490 LCFVVYPQDAPEEEENGPCPPSLLPATD 517


>gi|187423910 solute carrier family 7, member 9 [Homo sapiens]
          Length = 487

 Score =  410 bits (1053), Expect = e-114
 Identities = 208/474 (43%), Positives = 307/474 (64%), Gaps = 5/474 (1%)

Query: 25  SPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSV 84
           S  P+   L+KE+ L++G+ +IVG +IGSGIFVSPK VL  + + G  L+IWA  G+ + 
Sbjct: 18  SQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT 77

Query: 85  FGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMV 144
            GALC+AELGT I KSG  Y Y++EA+G   A++  W SL++I+PTS AII ++F+ Y+ 
Sbjct: 78  LGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVC 137

Query: 145 QPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIV 204
            P +  C  P    + LAAA I  ++ +N   V+ G+ VQ+IFT AK++ +  +I++G+V
Sbjct: 138 APFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLV 197

Query: 205 RLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIG 264
            L QG + +F+NSFEG+  +VG I+LA Y+ L++Y GW+ LNY+TEE++NP RNLPL+I 
Sbjct: 198 LLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAII 257

Query: 265 ISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGL 324
           I +P+VT  YIL NV+Y+TV+   ++L S AVAVTF D++    +WI+PL VA S  G  
Sbjct: 258 IGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAA 317

Query: 325 NASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINY 384
           N +   A RL +V  REGH+   +  I V R TP P+++F GI+A IY+   DI  L+NY
Sbjct: 318 NGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNY 377

Query: 385 YSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYS-DTINS 443
           +SF+ W F GL+I+G + +R+   +  RP+K+ V  P++  L ++FLV  P+ S  T   
Sbjct: 378 FSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEY 437

Query: 444 LIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLE 497
           L  +   LSGL FYFL +    H +  + ++I    T +LQ+L   V  E D E
Sbjct: 438 LYCVLFILSGLLFYFLFV----HYKFGWAQKISKPITMHLQMLMEVVPPEEDPE 487


>gi|7657591 solute carrier family 7, member 9 [Homo sapiens]
          Length = 487

 Score =  410 bits (1053), Expect = e-114
 Identities = 208/474 (43%), Positives = 307/474 (64%), Gaps = 5/474 (1%)

Query: 25  SPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSV 84
           S  P+   L+KE+ L++G+ +IVG +IGSGIFVSPK VL  + + G  L+IWA  G+ + 
Sbjct: 18  SQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT 77

Query: 85  FGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMV 144
            GALC+AELGT I KSG  Y Y++EA+G   A++  W SL++I+PTS AII ++F+ Y+ 
Sbjct: 78  LGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVC 137

Query: 145 QPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIV 204
            P +  C  P    + LAAA I  ++ +N   V+ G+ VQ+IFT AK++ +  +I++G+V
Sbjct: 138 APFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLV 197

Query: 205 RLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIG 264
            L QG + +F+NSFEG+  +VG I+LA Y+ L++Y GW+ LNY+TEE++NP RNLPL+I 
Sbjct: 198 LLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAII 257

Query: 265 ISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGL 324
           I +P+VT  YIL NV+Y+TV+   ++L S AVAVTF D++    +WI+PL VA S  G  
Sbjct: 258 IGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAA 317

Query: 325 NASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINY 384
           N +   A RL +V  REGH+   +  I V R TP P+++F GI+A IY+   DI  L+NY
Sbjct: 318 NGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNY 377

Query: 385 YSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYS-DTINS 443
           +SF+ W F GL+I+G + +R+   +  RP+K+ V  P++  L ++FLV  P+ S  T   
Sbjct: 378 FSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEY 437

Query: 444 LIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLE 497
           L  +   LSGL FYFL +    H +  + ++I    T +LQ+L   V  E D E
Sbjct: 438 LYCVLFILSGLLFYFLFV----HYKFGWAQKISKPITMHLQMLMEVVPPEEDPE 487


>gi|33286430 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 8 isoform b [Homo
           sapiens]
          Length = 332

 Score =  266 bits (679), Expect = 4e-71
 Identities = 139/315 (44%), Positives = 205/315 (65%), Gaps = 10/315 (3%)

Query: 202 GIVRLGQGASTHFE--NSFEGSSFA-VGDIALALYSALFSYSGWDTLNYVTEEIKNPERN 258
           GIV++ +G     E  N+FE      +G +ALA     F+Y GW+ LNYVTEE+ +P +N
Sbjct: 2   GIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKN 61

Query: 259 LPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVAL 318
           LP +I IS+P+VT +Y+  NVAY T +  +++LAS+AVAVTF +++ G+  WI+P+SVAL
Sbjct: 62  LPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVAL 121

Query: 319 SCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDI 378
           S FGG+N S+  +SRLFF G+REGHLP  + MIHV+R TP+P+LLF  I  L+ L   D+
Sbjct: 122 STFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDM 181

Query: 379 FQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYS 438
           + LINY  F  + F G+++ GQ+ LRWK+PD PRP+K+++ FPI++ L   FL+   L+S
Sbjct: 182 YTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWS 241

Query: 439 DTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLED 498
           + +   IG+AI L+G+P YFL +   +HK P      +   T   Q +C+ V  E++   
Sbjct: 242 EPVVCGIGLAIMLTGVPVYFLGV-YWQHK-PKCFSDFIELLTLVSQKMCVVVYPEVERGS 299

Query: 499 GGE-----MPKQRDP 508
           G E     M +Q+ P
Sbjct: 300 GTEEANEDMEEQQQP 314


>gi|71999149 solute carrier family 7, (cationic amino acid
           transporter, y+ system) member 13 [Homo sapiens]
          Length = 470

 Score =  246 bits (629), Expect = 3e-65
 Identities = 151/440 (34%), Positives = 243/440 (55%), Gaps = 11/440 (2%)

Query: 29  EQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSA-SFGLSLVIWAVGGLFSVFGA 87
           E+++LK+      G   ++ N+IG+GIFVSPKGVL YS  + G+SL +WA   + ++   
Sbjct: 5   EKIQLKRVFGYWWGTSFLLINIIGAGIFVSPKGVLAYSCMNVGVSLCVWAGCAILAMTST 64

Query: 88  LCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMVQPL 147
           LC AE+  +   SGA Y ++   FG  +AF+ LWTSL +      A  A+  A Y +QP 
Sbjct: 65  LCSAEISISFPCSGAQYYFLKRYFGSTVAFLNLWTSLFLGSGVV-AGQALLLAEYSIQPF 123

Query: 148 FPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIVRLG 207
           FPSC  P    + LA A + ++  +    VK  T +Q   +  KV  L  + + G+V L 
Sbjct: 124 FPSCSVPKLPKKCLALAMLWIVGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVVFLI 183

Query: 208 QGASTH---FENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIG 264
           +G   +   F+N+F+     +  +  A++   F+YSG      +  E+K P   +P  I 
Sbjct: 184 RGKKENVERFQNAFDAELPDISHLIQAIFQGYFAYSGGACFTLIAGELKKPRTTIPKCIF 243

Query: 265 ISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGL 324
            ++P+VT++Y+L N++Y TVL  R+IL+SDAVA+T+AD+ F    WI+P +++ S F  L
Sbjct: 244 TALPLVTVVYLLVNISYLTVLTPREILSSDAVAITWADRAFPSLAWIMPFAISTSLFSNL 303

Query: 325 NASIVAASRLFFVGSREGHLPDAICMI--HVERFTPVPSLLFNGIMALIYLCVEDIFQLI 382
             SI  +SR  ++ S+EG LP     +  H   FT V  L+  G +A+I   +  +  LI
Sbjct: 304 LISIFKSSRPIYLASQEGQLPLLFNTLNSHSSPFTAVLLLVTLGSLAII---LTSLIDLI 360

Query: 383 NYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLY-SDTI 441
           NY  F+   +  L ++G L  R++EP+   P K+ + FP+   +  + LV +PL  S  +
Sbjct: 361 NYIFFTGSLWSILLMIGILRRRYQEPNLSIPYKVFLSFPLATIVIDVGLVVIPLVKSPNV 420

Query: 442 NSLIGIAIALSGLPFYFLII 461
           + +  + + LSGL FY  +I
Sbjct: 421 HYVYVLLLVLSGLLFYIPLI 440


>gi|110347453 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 4 [Homo sapiens]
          Length = 635

 Score =  101 bits (252), Expect = 1e-21
 Identities = 90/406 (22%), Positives = 177/406 (43%), Gaps = 32/406 (7%)

Query: 30  QVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALC 89
           +  L++ +S L+   L VG M+GSG++V   G +    +    L+ + V  + S+  ALC
Sbjct: 30  ETSLRRCLSTLDLTLLGVGGMVGSGLYVLT-GAVAKEVAGPAVLLSFGVAAVASLLAALC 88

Query: 90  YAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLL--IIEPTSQAIIAITFANYMVQPL 147
           YAE G  + ++G++Y +   + G   AF+  W  LL  II     A +A  ++ Y+   +
Sbjct: 89  YAEFGARVPRTGSAYLFTYVSMGELWAFLIGWNVLLEYII---GGAAVARAWSGYL-DSM 144

Query: 148 FPSCFAPYAASRL--------------LAAACICLLT-FINCAYVKWGTLVQDIFTYAKV 192
           F      +  + +              LAA  I L + F++C   +  + +   F+   +
Sbjct: 145 FSHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCG-ARVSSWLNHTFSAISL 203

Query: 193 LALIAVIVAGIVRLGQGASTHFENSFEG--SSFAVGDIALALYSALFSYSGWDTLNYVTE 250
           L ++ +++ G +     A  H  ++ EG  + F    +     S  +++ G+D +   +E
Sbjct: 204 LVILFIVILGFIL----AQPHNWSADEGGFAPFGFSGVMAGTASCFYAFVGFDVIAASSE 259

Query: 251 EIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNW 310
           E +NP R++PL+I IS+ I    YIL +     ++    +    A+A  F  + +    +
Sbjct: 260 EAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGF 319

Query: 311 IIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMAL 370
           I+      +    L + + +  R+ +  + +G        +H     PV   L  G++  
Sbjct: 320 IVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTA 379

Query: 371 IYLCVEDIFQLINYYSFS---YWFFVGLSIVGQLYLRWKEPDRPRP 413
               + D+  L+ + S      + FV  SI+   + +   P  P P
Sbjct: 380 FLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSSPPSSPGP 425


>gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo
           sapiens]
          Length = 658

 Score = 92.4 bits (228), Expect = 9e-19
 Identities = 97/414 (23%), Positives = 176/414 (42%), Gaps = 40/414 (9%)

Query: 29  EQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVI-WAVGGLFSVFGA 87
           E  KL + +S ++ + L VG+ +G+G++V    V    A  G S+V+ + +  L SV   
Sbjct: 26  EDTKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVA--KADSGPSIVVSFLIAALASVMAG 83

Query: 88  LCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLL--IIEPTSQAII-AITFANYMV 144
           LCYAE G  + K+G++Y Y     G   AFI  W  +L  +I  +S A   + TF   + 
Sbjct: 84  LCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLS 143

Query: 145 QPL-------FPSCFAPYAASRLLAAACICLLTFINCAY-VKWGTLVQDIFTYAKVLALI 196
           + +       F   +   A      A C+ LL     ++ VK    V  +FT   +L L+
Sbjct: 144 KQIGQFLRTYFRMNYTGLAEYPDFFAVCLILLLAGLLSFGVKESAWVNKVFTAVNILVLL 203

Query: 197 AVIVAGIVRLG------------------------QGASTHFENSFEGSSFAVGDIALAL 232
            V+VAG V+                           G S +    F    F  G +A A 
Sbjct: 204 FVMVAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFT-GTLAGAA 262

Query: 233 YSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILA 292
            +  +++ G+D +    EE++NP++ +P+ I  S+ +  + Y   + A   ++    +  
Sbjct: 263 -TCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDE 321

Query: 293 SDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIH 352
              + V F    +G   +++      +    L  SI    R+ +  + +G L   +  I+
Sbjct: 322 KSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSIFPMPRVIYAMAEDGLLFKCLAQIN 381

Query: 353 VERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWK 406
            +  TP+ + L +G +A +   + D+  L++  S        L     L LR++
Sbjct: 382 SKTKTPIIATLSSGAVAALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQ 435


>gi|4507047 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 1 [Homo sapiens]
          Length = 629

 Score = 90.1 bits (222), Expect = 4e-18
 Identities = 103/426 (24%), Positives = 182/426 (42%), Gaps = 55/426 (12%)

Query: 29  EQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVI-WAVGGLFSVFGA 87
           E+ +L + ++  + V L VG+ +G+G++V    V   +A  G ++VI + +  L SV   
Sbjct: 24  EETRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVARENA--GPAIVISFLIAALASVLAG 81

Query: 88  LCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLL--IIEPTSQA-IIAITFANYMV 144
           LCY E G  + K+G++Y Y     G   AFI  W  +L  II  +S A   + TF   + 
Sbjct: 82  LCYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIG 141

Query: 145 QPL------FPSCFAPYAASR---LLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLAL 195
           +P+        +  AP   +    + A   I +LT +    VK   +V  IFT   VL L
Sbjct: 142 RPIGEFSRTHMTLNAPGVLAENPDIFAVIIILILTGLLTLGVKESAMVNKIFTCINVLVL 201

Query: 196 IAVIVAGIVRLGQGASTHFENSFEGSS---------------------FAVGDIALALYS 234
             ++V+G V+         E  F  +S                     F    +     +
Sbjct: 202 GFIMVSGFVKGSVKNWQLTEEDFGNTSGRLCLNNDTKEGKPGVGGFMPFGFSGVLSGAAT 261

Query: 235 ALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYI-----LTNVAYYTVLDMRD 289
             +++ G+D +    EE+KNP++ +P+ I  S+ I  I Y      LT +  Y  LD   
Sbjct: 262 CFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMPYFCLDNNS 321

Query: 290 ILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAA----SRLFFVGSREGHLP 345
            L      V +    +         +VA+     L+AS++ +     R+ +  + +G L 
Sbjct: 322 PLPDAFKHVGWEGAKY---------AVAVGSLCALSASLLGSMFPMPRVIYAMAEDGLLF 372

Query: 346 DAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRW 405
             +  ++    TP+ + L +G +A +   + D+  L++  S        L     L LR+
Sbjct: 373 KFLANVNDRTKTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVAACVLVLRY 432

Query: 406 KEPDRP 411
            +P++P
Sbjct: 433 -QPEQP 437


>gi|114326550 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 3 [Homo sapiens]
          Length = 619

 Score = 90.1 bits (222), Expect = 4e-18
 Identities = 99/427 (23%), Positives = 172/427 (40%), Gaps = 57/427 (13%)

Query: 27  GPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVI-WAVGGLFSVF 85
           G  + +L + +S L+ V L VG+ +G+G++V    V    A  G S+VI + V  L SV 
Sbjct: 22  GMAETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKA--GPSIVICFLVAALSSVL 79

Query: 86  GALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLL--IIEPTSQA-----IIAIT 138
             LCYAE G  + +SG++Y Y     G   AF   W  +L  +I   S A          
Sbjct: 80  AGLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNL 139

Query: 139 FANYMVQPL-------FPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAK 191
             N++ + L        P   A Y      A   + LLT +         LV  +FT   
Sbjct: 140 IGNHISKTLQGSIALHVPHVLAEY--PDFFALGLVLLLTGLLALGASESALVTKVFTGVN 197

Query: 192 VLALIAVIVAGIVR----------------------------LGQGASTHFENSFEGSSF 223
           +L L  V+++G V+                            LG G    F   FEG   
Sbjct: 198 LLVLGFVMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPF--GFEG--- 252

Query: 224 AVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYT 283
               I     +  +++ G+D +    EE +NP+R++P+ I IS+ +  + Y   + A   
Sbjct: 253 ----ILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTL 308

Query: 284 VLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGH 343
           ++    +     +   F    +    +++ +    +    L  S+    R+ +  + +G 
Sbjct: 309 MMPYYQLQPESPLPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGL 368

Query: 344 LPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYL 403
           L   +  IH    TP+ + + +GI+A     +  +  L++  S        L  +  L L
Sbjct: 369 LFRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLIL 428

Query: 404 RWKEPDR 410
           R+ +PD+
Sbjct: 429 RY-QPDQ 434


>gi|114326544 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 3 [Homo sapiens]
          Length = 619

 Score = 90.1 bits (222), Expect = 4e-18
 Identities = 99/427 (23%), Positives = 172/427 (40%), Gaps = 57/427 (13%)

Query: 27  GPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVI-WAVGGLFSVF 85
           G  + +L + +S L+ V L VG+ +G+G++V    V    A  G S+VI + V  L SV 
Sbjct: 22  GMAETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKA--GPSIVICFLVAALSSVL 79

Query: 86  GALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLL--IIEPTSQA-----IIAIT 138
             LCYAE G  + +SG++Y Y     G   AF   W  +L  +I   S A          
Sbjct: 80  AGLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNL 139

Query: 139 FANYMVQPL-------FPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAK 191
             N++ + L        P   A Y      A   + LLT +         LV  +FT   
Sbjct: 140 IGNHISKTLQGSIALHVPHVLAEY--PDFFALGLVLLLTGLLALGASESALVTKVFTGVN 197

Query: 192 VLALIAVIVAGIVR----------------------------LGQGASTHFENSFEGSSF 223
           +L L  V+++G V+                            LG G    F   FEG   
Sbjct: 198 LLVLGFVMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPF--GFEG--- 252

Query: 224 AVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYT 283
               I     +  +++ G+D +    EE +NP+R++P+ I IS+ +  + Y   + A   
Sbjct: 253 ----ILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTL 308

Query: 284 VLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGH 343
           ++    +     +   F    +    +++ +    +    L  S+    R+ +  + +G 
Sbjct: 309 MMPYYQLQPESPLPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGL 368

Query: 344 LPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYL 403
           L   +  IH    TP+ + + +GI+A     +  +  L++  S        L  +  L L
Sbjct: 369 LFRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLIL 428

Query: 404 RWKEPDR 410
           R+ +PD+
Sbjct: 429 RY-QPDQ 434


>gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo
           sapiens]
          Length = 697

 Score = 89.4 bits (220), Expect = 7e-18
 Identities = 97/414 (23%), Positives = 177/414 (42%), Gaps = 41/414 (9%)

Query: 29  EQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVI-WAVGGLFSVFGA 87
           E  KL + +S ++ + L VG+ +G+G++V    V    A  G S+V+ + +  L SV   
Sbjct: 66  EDTKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVA--KADSGPSIVVSFLIAALASVMAG 123

Query: 88  LCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLL--IIEPTSQAII-AITFANYMV 144
           LCYAE G  + K+G++Y Y     G   AFI  W  +L  +I  +S A   + TF   + 
Sbjct: 124 LCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLS 183

Query: 145 QPL-------FPSCFAPYAASRLLAAACICLLTFINCAY-VKWGTLVQDIFTYAKVLALI 196
           + +       F   +   A      A C+ LL     ++ VK    V  +FT   +L L+
Sbjct: 184 KQIGQFLRTYFRMNYTGLAEYPDFFAVCLILLLAGLLSFGVKESAWVNKVFTAVNILVLL 243

Query: 197 AVIVAGIVRLG------------------------QGASTHFENSFEGSSFAVGDIALAL 232
            V+VAG V+                           G S +    F    F  G +A A 
Sbjct: 244 FVMVAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFT-GTLAGAA 302

Query: 233 YSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILA 292
            +  +++ G+D +    EE++NP++ +P+ I  S+ +  + Y   + A   ++    +  
Sbjct: 303 -TCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDE 361

Query: 293 SDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIH 352
              + V F    +G   +++      +    L  S+    R+ F  +R+G L   +  + 
Sbjct: 362 KSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVS 421

Query: 353 VERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWK 406
            +R +PV + L  G+++ +   + D+  L++  S        L     L LR++
Sbjct: 422 -KRQSPVAATLTAGVISALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQ 474


>gi|181337167 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 14 [Homo sapiens]
          Length = 771

 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 97/413 (23%), Positives = 167/413 (40%), Gaps = 66/413 (15%)

Query: 32  KLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALCYA 91
           KL + ++ ++ + L VG+ +G+G++V    V    A  G+ +V + +  + S+   +CYA
Sbjct: 48  KLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGV-IVSFIIAAVASILSGVCYA 106

Query: 92  ELGTTIKKS-GASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMVQPLFPS 150
           E G  + K+ G++Y Y     G F+AF   W  +L      + +I        +  +F S
Sbjct: 107 EFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLIL------EYLIGTAAGASALSSMFDS 160

Query: 151 CFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLAL-IAVIVAGIVRLGQG 209
             A +  SR +A +   L             L +   +Y  +LAL IAVIV  IV LG  
Sbjct: 161 -LANHTISRWMADSVGTL-----------NGLGKGEESYPDLLALLIAVIVTIIVALGVK 208

Query: 210 ASTHFENSFEGSSFAV---------------------------GDIALALYSALFSYSGW 242
            S  F N     + AV                             +     +  +++ G+
Sbjct: 209 NSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAEGQFLPHGWSGVLQGAATCFYAFIGF 268

Query: 243 DTLNYVTEEIKNPERNLPLSIGISMPI-----VTIIYILTNVAYYTVLDMRDILASDAVA 297
           D +    EE KNP  ++P +I  S+ I     V++  ILT +  Y  +D    L    VA
Sbjct: 269 DIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEMFVA 328

Query: 298 VTFADQIFGIFNWIIPLSVALSCFGGLNASIVAA----SRLFFVGSREGHLPDAICMIHV 353
             F         +     VA+    GL  S++ +     R+ +  + +G L   +  +  
Sbjct: 329 HGF---------YAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSS 379

Query: 354 ERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWK 406
              TPV + + +G +A +   +  +  LI   S        L  V  L LR++
Sbjct: 380 YTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQ 432


>gi|198041678 solute carrier family 12 (potassium-chloride
           transporter), member 5 isoform 1 [Homo sapiens]
          Length = 1139

 Score = 33.5 bits (75), Expect = 0.47
 Identities = 48/242 (19%), Positives = 101/242 (41%), Gaps = 19/242 (7%)

Query: 251 EIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLD---MRDILASDAVAVTFADQIFGI 307
           ++++ ++++P    +++   + +YI + V +   ++   +RD              +   
Sbjct: 446 DLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWP 505

Query: 308 FNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVE-RFTPVPSLLFNG 366
             W+I +    S  G    S+  A RL    SR+G +P      H +    P  +LL   
Sbjct: 506 SPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLTA 565

Query: 367 I---MALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLR---WKEPDRPRPLKLSVFF 420
               + ++   ++++  +++ +    + FV L+   Q  LR   W+   R     LS F 
Sbjct: 566 CICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLS-FL 624

Query: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480
            +  CL  +F+ +         +L+ + IA  GL + ++  R  E +    +R +  SA 
Sbjct: 625 GMSLCLALMFICS------WYYALVAMLIA--GLIYKYIEYRGAEKEWGDGIRGLSLSAA 676

Query: 481 RY 482
           RY
Sbjct: 677 RY 678


>gi|11968148 solute carrier family 12 (potassium-chloride
           transporter), member 5 isoform 2 [Homo sapiens]
          Length = 1116

 Score = 33.5 bits (75), Expect = 0.47
 Identities = 48/242 (19%), Positives = 101/242 (41%), Gaps = 19/242 (7%)

Query: 251 EIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLD---MRDILASDAVAVTFADQIFGI 307
           ++++ ++++P    +++   + +YI + V +   ++   +RD              +   
Sbjct: 423 DLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWP 482

Query: 308 FNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVE-RFTPVPSLLFNG 366
             W+I +    S  G    S+  A RL    SR+G +P      H +    P  +LL   
Sbjct: 483 SPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLTA 542

Query: 367 I---MALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLR---WKEPDRPRPLKLSVFF 420
               + ++   ++++  +++ +    + FV L+   Q  LR   W+   R     LS F 
Sbjct: 543 CICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLS-FL 601

Query: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480
            +  CL  +F+ +         +L+ + IA  GL + ++  R  E +    +R +  SA 
Sbjct: 602 GMSLCLALMFICS------WYYALVAMLIA--GLIYKYIEYRGAEKEWGDGIRGLSLSAA 653

Query: 481 RY 482
           RY
Sbjct: 654 RY 655


>gi|34916028 solute carrier family 16 (monocarboxylic acid
           transporters), member 9 [Homo sapiens]
          Length = 509

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 4/93 (4%)

Query: 313 PLSVALSCFGGLNASIVAASRLFFVGSRE---GHLPDAICMIHVERFTPVPSLLFNGIMA 369
           PL+V +     L+A      +  +VGS     G L   +C + V  F   P  +F+G M 
Sbjct: 30  PLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLASPVCSLCVSSFGARPVTIFSGFMV 89

Query: 370 LIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLY 402
              L +      I +  FSY   VGL   G LY
Sbjct: 90  AGGLMLSSFAPNIYFLFFSYGIVVGLG-CGLLY 121


>gi|219689113 two pore segment channel 1 isoform 1 [Homo sapiens]
          Length = 888

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 6/51 (11%)

Query: 437 YSDTINSLIGI-AIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVL 486
           +S T+ + +G+ A+AL+  PFYF+++      RPL L R+     RY  VL
Sbjct: 584 FSVTVFAFLGLLALALNMEPFYFIVV-----LRPLQLLRLFKLKERYRNVL 629


>gi|29725622 two pore segment channel 1 isoform 2 [Homo sapiens]
          Length = 816

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 6/51 (11%)

Query: 437 YSDTINSLIGI-AIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVL 486
           +S T+ + +G+ A+AL+  PFYF+++      RPL L R+     RY  VL
Sbjct: 512 FSVTVFAFLGLLALALNMEPFYFIVV-----LRPLQLLRLFKLKERYRNVL 557


>gi|41352721 solute carrier family 36 member 1 [Homo sapiens]
          Length = 476

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 16/42 (38%), Positives = 27/42 (64%), Gaps = 1/42 (2%)

Query: 234 SALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYI 275
           +A+FS+ G   +  +  ++K+P R  PL + + M IVTI+YI
Sbjct: 264 TAIFSFEGIGMVLPLENKMKDP-RKFPLILYLGMVIVTILYI 304


>gi|4759114 solute carrier family 16, member 4 [Homo sapiens]
          Length = 487

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 28/101 (27%), Positives = 40/101 (39%), Gaps = 16/101 (15%)

Query: 43  VCLIVGNMIGS--GIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALCYA--------- 91
           +C I+G    S  G FV   G LI S +  +  +   +G L  +  A  Y          
Sbjct: 80  ICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKY 139

Query: 92  -----ELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLII 127
                 L T I +SG    ++L  F  FL  +  WT  LI+
Sbjct: 140 FKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGALIL 180


>gi|36951034 G protein-coupled receptor 78 [Homo sapiens]
          Length = 363

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 26/93 (27%)

Query: 135 IAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTL---------VQD 185
           I I  A +++      CFAPY  +RL       L+ F+     +WG L         V D
Sbjct: 243 IGIAIATFLI------CFAPYVMTRLAE-----LVPFVT-VNAQWGILSKCLTYSKAVAD 290

Query: 186 IFTYAKVLALIAVIVAGIV-----RLGQGASTH 213
            FTY+ +      ++AG+V     R  + ASTH
Sbjct: 291 PFTYSLLRRPFRQVLAGMVHRLLKRTPRPASTH 323


>gi|166235895 ectonucleoside triphosphate diphosphohydrolase 6
           isoform 2 [Homo sapiens]
          Length = 467

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 6/78 (7%)

Query: 184 QDI-FTYAKVLALIAVIVAGIVRL----GQGASTHFENSFEGSSFAVGDIALALYSALFS 238
           QDI F + K   L+    AG+  L     Q      +  F+ S F VGD  +++ +    
Sbjct: 148 QDIPFDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVFKASPFLVGDDCVSIMNGTDE 207

Query: 239 -YSGWDTLNYVTEEIKNP 255
             S W T+N++T  +K P
Sbjct: 208 GVSAWITINFLTGSLKTP 225


>gi|166235893 ectonucleoside triphosphate diphosphohydrolase 6
           isoform 1 [Homo sapiens]
          Length = 484

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 6/78 (7%)

Query: 184 QDI-FTYAKVLALIAVIVAGIVRL----GQGASTHFENSFEGSSFAVGDIALALYSALFS 238
           QDI F + K   L+    AG+  L     Q      +  F+ S F VGD  +++ +    
Sbjct: 165 QDIPFDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVFKASPFLVGDDCVSIMNGTDE 224

Query: 239 -YSGWDTLNYVTEEIKNP 255
             S W T+N++T  +K P
Sbjct: 225 GVSAWITINFLTGSLKTP 242


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.142    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,055,071
Number of Sequences: 37866
Number of extensions: 773919
Number of successful extensions: 2123
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2047
Number of HSP's gapped (non-prelim): 42
length of query: 511
length of database: 18,247,518
effective HSP length: 107
effective length of query: 404
effective length of database: 14,195,856
effective search space: 5735125824
effective search space used: 5735125824
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.