BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|186910304 solute carrier family 7 member 7 [Homo sapiens] (511 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|186910308 solute carrier family 7 member 7 [Homo sapiens] 1013 0.0 gi|186910306 solute carrier family 7 member 7 [Homo sapiens] 1013 0.0 gi|186910304 solute carrier family 7 member 7 [Homo sapiens] 1013 0.0 gi|115648063 solute carrier family 7 (cationic amino acid transp... 759 0.0 gi|115648022 solute carrier family 7 (cationic amino acid transp... 759 0.0 gi|33286428 solute carrier family 7 (cationic amino acid transpo... 478 e-135 gi|71979932 solute carrier family 7 (cationic amino acid transpo... 475 e-134 gi|7657683 solute carrier family 7, (cationic amino acid transpo... 443 e-124 gi|9790235 solute carrier family 7, member 10 [Homo sapiens] 430 e-120 gi|187423910 solute carrier family 7, member 9 [Homo sapiens] 410 e-114 gi|7657591 solute carrier family 7, member 9 [Homo sapiens] 410 e-114 gi|33286430 solute carrier family 7 (cationic amino acid transpo... 266 4e-71 gi|71999149 solute carrier family 7, (cationic amino acid transp... 246 3e-65 gi|110347453 solute carrier family 7 (cationic amino acid transp... 101 1e-21 gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s... 92 9e-19 gi|4507047 solute carrier family 7 (cationic amino acid transpor... 90 4e-18 gi|114326550 solute carrier family 7 (cationic amino acid transp... 90 4e-18 gi|114326544 solute carrier family 7 (cationic amino acid transp... 90 4e-18 gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo s... 89 7e-18 gi|181337167 solute carrier family 7 (cationic amino acid transp... 74 3e-13 gi|198041678 solute carrier family 12 (potassium-chloride transp... 33 0.47 gi|11968148 solute carrier family 12 (potassium-chloride transpo... 33 0.47 gi|34916028 solute carrier family 16 (monocarboxylic acid transp... 32 1.8 gi|219689113 two pore segment channel 1 isoform 1 [Homo sapiens] 31 3.1 gi|29725622 two pore segment channel 1 isoform 2 [Homo sapiens] 31 3.1 gi|41352721 solute carrier family 36 member 1 [Homo sapiens] 30 4.0 gi|4759114 solute carrier family 16, member 4 [Homo sapiens] 30 4.0 gi|36951034 G protein-coupled receptor 78 [Homo sapiens] 30 4.0 gi|166235895 ectonucleoside triphosphate diphosphohydrolase 6 is... 30 4.0 gi|166235893 ectonucleoside triphosphate diphosphohydrolase 6 is... 30 4.0 >gi|186910308 solute carrier family 7 member 7 [Homo sapiens] Length = 511 Score = 1013 bits (2618), Expect = 0.0 Identities = 511/511 (100%), Positives = 511/511 (100%) Query: 1 MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPK 60 MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPK Sbjct: 1 MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPK 60 Query: 61 GVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRL 120 GVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRL Sbjct: 61 GVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRL 120 Query: 121 WTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWG 180 WTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWG Sbjct: 121 WTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWG 180 Query: 181 TLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYS 240 TLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYS Sbjct: 181 TLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYS 240 Query: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF Sbjct: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300 Query: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP Sbjct: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360 Query: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF Sbjct: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420 Query: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT Sbjct: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480 Query: 481 RYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN 511 RYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN Sbjct: 481 RYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN 511 >gi|186910306 solute carrier family 7 member 7 [Homo sapiens] Length = 511 Score = 1013 bits (2618), Expect = 0.0 Identities = 511/511 (100%), Positives = 511/511 (100%) Query: 1 MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPK 60 MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPK Sbjct: 1 MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPK 60 Query: 61 GVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRL 120 GVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRL Sbjct: 61 GVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRL 120 Query: 121 WTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWG 180 WTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWG Sbjct: 121 WTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWG 180 Query: 181 TLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYS 240 TLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYS Sbjct: 181 TLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYS 240 Query: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF Sbjct: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300 Query: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP Sbjct: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360 Query: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF Sbjct: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420 Query: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT Sbjct: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480 Query: 481 RYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN 511 RYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN Sbjct: 481 RYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN 511 >gi|186910304 solute carrier family 7 member 7 [Homo sapiens] Length = 511 Score = 1013 bits (2618), Expect = 0.0 Identities = 511/511 (100%), Positives = 511/511 (100%) Query: 1 MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPK 60 MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPK Sbjct: 1 MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPK 60 Query: 61 GVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRL 120 GVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRL Sbjct: 61 GVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRL 120 Query: 121 WTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWG 180 WTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWG Sbjct: 121 WTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWG 180 Query: 181 TLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYS 240 TLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYS Sbjct: 181 TLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYS 240 Query: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF Sbjct: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300 Query: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP Sbjct: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360 Query: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF Sbjct: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420 Query: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT Sbjct: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480 Query: 481 RYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN 511 RYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN Sbjct: 481 RYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN 511 >gi|115648063 solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 [Homo sapiens] Length = 515 Score = 759 bits (1959), Expect = 0.0 Identities = 368/500 (73%), Positives = 439/500 (87%), Gaps = 7/500 (1%) Query: 11 SQPEVETSPLGDGASP---GPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSA 67 SQ +VE D +SP E ++LKKEISLLNGV L+VGNMIGSGIFVSPKGVL+++A Sbjct: 20 SQSQVEE----DVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTA 75 Query: 68 SFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLII 127 S+G+SL++WA+GGLFSV GALCYAELGTTI KSGASYAYILEAFGGF+AFIRLW SLL++ Sbjct: 76 SYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVV 135 Query: 128 EPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIF 187 EPT QAIIAITFANY++QP FPSC PY A RLLAAACICLLTF+NCAYVKWGT VQD F Sbjct: 136 EPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTF 195 Query: 188 TYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNY 247 TYAKV+ALIA+IV G+V+L QG S HF+++FEGSS+ +G+++LALYSALFSYSGWDTLN+ Sbjct: 196 TYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNF 255 Query: 248 VTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGI 307 VTEEIKNPERNLPL+IGISMPIVT+IYILTNVAYYTVL++ D+L+SDAVAVTFADQ FG+ Sbjct: 256 VTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGM 315 Query: 308 FNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGI 367 F+W IP++VALSCFGGLNASI A+SRLFFVGSREGHLPD + MIH+ERFTP+P+LLFN Sbjct: 316 FSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCT 375 Query: 368 MALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLC 427 MALIYL VED+FQLINY+SFSYWFFVGLS+VGQLYLRWKEP RPRPLKLSVFFPIVFC+C Sbjct: 376 MALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCIC 435 Query: 428 TIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLC 487 ++FLV VPL++DTINSLIGI IALSG+PFYF+ + +PE +RPL++R ++ + TR Q LC Sbjct: 436 SVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLC 495 Query: 488 MSVAAEMDLEDGGEMPKQRD 507 V E+D+ + + ++ D Sbjct: 496 FCVLTELDVAEEKKDERKTD 515 >gi|115648022 solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 [Homo sapiens] Length = 515 Score = 759 bits (1959), Expect = 0.0 Identities = 368/500 (73%), Positives = 439/500 (87%), Gaps = 7/500 (1%) Query: 11 SQPEVETSPLGDGASP---GPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSA 67 SQ +VE D +SP E ++LKKEISLLNGV L+VGNMIGSGIFVSPKGVL+++A Sbjct: 20 SQSQVEE----DVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTA 75 Query: 68 SFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLII 127 S+G+SL++WA+GGLFSV GALCYAELGTTI KSGASYAYILEAFGGF+AFIRLW SLL++ Sbjct: 76 SYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVV 135 Query: 128 EPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIF 187 EPT QAIIAITFANY++QP FPSC PY A RLLAAACICLLTF+NCAYVKWGT VQD F Sbjct: 136 EPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTF 195 Query: 188 TYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNY 247 TYAKV+ALIA+IV G+V+L QG S HF+++FEGSS+ +G+++LALYSALFSYSGWDTLN+ Sbjct: 196 TYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNF 255 Query: 248 VTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGI 307 VTEEIKNPERNLPL+IGISMPIVT+IYILTNVAYYTVL++ D+L+SDAVAVTFADQ FG+ Sbjct: 256 VTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGM 315 Query: 308 FNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGI 367 F+W IP++VALSCFGGLNASI A+SRLFFVGSREGHLPD + MIH+ERFTP+P+LLFN Sbjct: 316 FSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCT 375 Query: 368 MALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLC 427 MALIYL VED+FQLINY+SFSYWFFVGLS+VGQLYLRWKEP RPRPLKLSVFFPIVFC+C Sbjct: 376 MALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCIC 435 Query: 428 TIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLC 487 ++FLV VPL++DTINSLIGI IALSG+PFYF+ + +PE +RPL++R ++ + TR Q LC Sbjct: 436 SVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLC 495 Query: 488 MSVAAEMDLEDGGEMPKQRD 507 V E+D+ + + ++ D Sbjct: 496 FCVLTELDVAEEKKDERKTD 515 >gi|33286428 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 isoform a [Homo sapiens] Length = 535 Score = 478 bits (1230), Expect = e-135 Identities = 246/514 (47%), Positives = 348/514 (67%), Gaps = 13/514 (2%) Query: 3 DSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGV 62 ++TE + E + SP A G V LKKEI L++ +IVGN+IGSGIFVSPKGV Sbjct: 9 NNTEKKHPGGGESDASP---EAGSGGGGVALKKEIGLVSACGIIVGNIIGSGIFVSPKGV 65 Query: 63 LIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWT 122 L + S GL+L++W V G +V GALCYAELG TI KSG Y+Y+ + FGG F+RLW Sbjct: 66 LENAGSVGLALIVWIVTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWI 125 Query: 123 SLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTL 182 ++L+I PT+QA+IA+TF+NY++QPLFP+CF P + RLLAA C+ LLT++NC+ V+W T Sbjct: 126 AVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATR 185 Query: 183 VQDIFTYAKVLALIAVIVAGIVRLGQGASTHFE--NSFEGSSFA-VGDIALALYSALFSY 239 VQDIFT K+LAL +I+ GIV++ +G E N+FE +G +ALA F+Y Sbjct: 186 VQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAY 245 Query: 240 SGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVT 299 GW+ LNYVTEE+ +P +NLP +I IS+P+VT +Y+ NVAY T + +++LAS+AVAVT Sbjct: 246 GGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVT 305 Query: 300 FADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPV 359 F +++ G+ WI+P+SVALS FGG+N S+ +SRLFF G+REGHLP + MIHV+R TP+ Sbjct: 306 FGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPI 365 Query: 360 PSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVF 419 P+LLF I L+ L D++ LINY F + F G+++ GQ+ LRWK+PD PRP+K+++ Sbjct: 366 PALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLL 425 Query: 420 FPIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSA 479 FPI++ L FL+ L+S+ + IG+AI L+G+P YFL + +HK P + Sbjct: 426 FPIIYLLFWAFLLVFSLWSEPVVCGIGLAIMLTGVPVYFLGV-YWQHK-PKCFSDFIELL 483 Query: 480 TRYLQVLCMSVAAEMDLEDGGE-----MPKQRDP 508 T Q +C+ V E++ G E M +Q+ P Sbjct: 484 TLVSQKMCVVVYPEVERGSGTEEANEDMEEQQQP 517 >gi|71979932 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 [Homo sapiens] Length = 507 Score = 475 bits (1223), Expect = e-134 Identities = 243/493 (49%), Positives = 339/493 (68%), Gaps = 9/493 (1%) Query: 3 DSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGV 62 ++ E +A++ ++P G+G E V L++ I+LLNGV +IVG +IGSGIFV+P GV Sbjct: 21 EAREKMLAAKSADGSAPAGEG-----EGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGV 75 Query: 63 LIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWT 122 L + S GL+LV+WA G+FS+ GALCYAELGTTI KSG YAY+LE +G AF++LW Sbjct: 76 LKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWI 135 Query: 123 SLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTL 182 LLII P+SQ I+A+ FA Y+++PLFP+C P A++L+A C+ LLT +NC VK T Sbjct: 136 ELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATR 195 Query: 183 VQDIFTYAKVLALIAVIVAGIVRLGQGASTHFEN--SFEGSSFAVGDIALALYSALFSYS 240 VQD F AK+LAL +I+ G V++G+G ++ + SFEG+ VG+I LALYS LF+Y Sbjct: 196 VQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYG 255 Query: 241 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF 300 GW+ LN+VTEE+ NP RNLPL+I IS+PIVT++Y+LTN+AY+T L +L+S+AVAV F Sbjct: 256 GWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDF 315 Query: 301 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP 360 + G+ +WIIP+ V LSCFG +N S+ +SRLFFVGSREGHLP + MIH + TPVP Sbjct: 316 GNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVP 375 Query: 361 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF 420 SL+F +M L+Y +DIF +IN++SF W V L+I+G ++LR ++P+ RP+K+++ Sbjct: 376 SLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLAL 435 Query: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480 P+ F L +FL+AV + + IG I LSGLP YF V +P +L + + S T Sbjct: 436 PVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYF--FGVWWKNKPKWLLQGIFSTT 493 Query: 481 RYLQVLCMSVAAE 493 Q L V E Sbjct: 494 VLCQKLMQVVPQE 506 >gi|7657683 solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 [Homo sapiens] Length = 501 Score = 443 bits (1139), Expect = e-124 Identities = 214/474 (45%), Positives = 323/474 (68%), Gaps = 2/474 (0%) Query: 20 LGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVG 79 LG+ PG E+V+LK++++LL GV +I+G +IG+GIF+SPKGVL + S G+SL IW V Sbjct: 27 LGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTVC 86 Query: 80 GLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITF 139 G+ S+FGAL YAELGTTIKKSG Y YILE FG AF+R+W LLII P + A+I++ F Sbjct: 87 GVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAF 146 Query: 140 ANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVI 199 Y+++P F C P A +L+ A I ++ +N V W +Q T+ K+ A++ +I Sbjct: 147 GRYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIII 206 Query: 200 VAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNL 259 V G+++L +G + +F+++F G ++ + LA Y +++Y+GW LN+VTEE++NPE+ + Sbjct: 207 VPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTI 266 Query: 260 PLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALS 319 PL+I ISM IVTI Y+LTNVAY+T ++ ++L S+AVAVTF++++ G F+ +P+ VALS Sbjct: 267 PLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALS 326 Query: 320 CFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIF 379 CFG +N + A SRLF+V SREGHLP+ + MIHV + TP+P+++ + +I L D+ Sbjct: 327 CFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLD 386 Query: 380 QLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYSD 439 L+N+ SF+ W F+GL++ G +YLR+K PD RP K+ +F P +F +F+VA+ LYSD Sbjct: 387 SLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSD 446 Query: 440 TINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAE 493 ++ IG I L+G+P Y+L I K+P + R + TR LQ++ V E Sbjct: 447 PFSTGIGFVITLTGVPAYYLFI--IWDKKPRWFRIMSEKITRTLQIILEVVPEE 498 >gi|9790235 solute carrier family 7, member 10 [Homo sapiens] Length = 523 Score = 430 bits (1106), Expect = e-120 Identities = 219/508 (43%), Positives = 328/508 (64%), Gaps = 13/508 (2%) Query: 12 QPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGL 71 +P SP+ E+V LKKEI LL+ +I+GN+IGSGIF+SPKGVL +S S GL Sbjct: 15 RPAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGL 74 Query: 72 SLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTS 131 +L +W +GG + G+LCYAELG I KSG YAY+ E FGG F+ LW+++LI+ PTS Sbjct: 75 ALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTS 134 Query: 132 QAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAK 191 A+I++TF+NY++QP+FP+C P ASR+L+ AC+ LLT++N + V+W T +QD+FT K Sbjct: 135 LAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGK 194 Query: 192 VLALIAVIVAGIVRLGQGASTHFENSFEGSSFA------VGDIALALYSALFSYSGWDTL 245 +LAL +I G++++ QG HFE ++FA VG +ALA F++SGW+ L Sbjct: 195 LLALSLIIGVGLLQIFQG---HFEELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFL 251 Query: 246 NYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIF 305 NYVTEE+ + +NLP +I IS+P+VT +Y TN+AY+T + +++L+S+AVAVTF +++ Sbjct: 252 NYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLL 311 Query: 306 GIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFN 365 G F+W++P+SVALS FGG+N + SRL F G+REGHLP + MIHV TP+P+LL Sbjct: 312 GYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVC 371 Query: 366 GIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFC 425 + + V D + LINY SF + G++I+G L LRW+ P RP+K+++ P+ + Sbjct: 372 CGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYL 431 Query: 426 LCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQV 485 + FL+ S+ + +G+ I L+G+P +FL V +P + R+ S T + Q Sbjct: 432 VFWAFLLVFSFISEPMVCGVGVIIILTGVPIFFL--GVFWRSKPKCVHRLTESMTHWGQE 489 Query: 486 LCMSVAAE--MDLEDGGEMPKQRDPKSN 511 LC V + + E+ G P P ++ Sbjct: 490 LCFVVYPQDAPEEEENGPCPPSLLPATD 517 >gi|187423910 solute carrier family 7, member 9 [Homo sapiens] Length = 487 Score = 410 bits (1053), Expect = e-114 Identities = 208/474 (43%), Positives = 307/474 (64%), Gaps = 5/474 (1%) Query: 25 SPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSV 84 S P+ L+KE+ L++G+ +IVG +IGSGIFVSPK VL + + G L+IWA G+ + Sbjct: 18 SQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT 77 Query: 85 FGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMV 144 GALC+AELGT I KSG Y Y++EA+G A++ W SL++I+PTS AII ++F+ Y+ Sbjct: 78 LGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVC 137 Query: 145 QPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIV 204 P + C P + LAAA I ++ +N V+ G+ VQ+IFT AK++ + +I++G+V Sbjct: 138 APFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLV 197 Query: 205 RLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIG 264 L QG + +F+NSFEG+ +VG I+LA Y+ L++Y GW+ LNY+TEE++NP RNLPL+I Sbjct: 198 LLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAII 257 Query: 265 ISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGL 324 I +P+VT YIL NV+Y+TV+ ++L S AVAVTF D++ +WI+PL VA S G Sbjct: 258 IGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAA 317 Query: 325 NASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINY 384 N + A RL +V REGH+ + I V R TP P+++F GI+A IY+ DI L+NY Sbjct: 318 NGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNY 377 Query: 385 YSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYS-DTINS 443 +SF+ W F GL+I+G + +R+ + RP+K+ V P++ L ++FLV P+ S T Sbjct: 378 FSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEY 437 Query: 444 LIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLE 497 L + LSGL FYFL + H + + ++I T +LQ+L V E D E Sbjct: 438 LYCVLFILSGLLFYFLFV----HYKFGWAQKISKPITMHLQMLMEVVPPEEDPE 487 >gi|7657591 solute carrier family 7, member 9 [Homo sapiens] Length = 487 Score = 410 bits (1053), Expect = e-114 Identities = 208/474 (43%), Positives = 307/474 (64%), Gaps = 5/474 (1%) Query: 25 SPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSV 84 S P+ L+KE+ L++G+ +IVG +IGSGIFVSPK VL + + G L+IWA G+ + Sbjct: 18 SQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT 77 Query: 85 FGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMV 144 GALC+AELGT I KSG Y Y++EA+G A++ W SL++I+PTS AII ++F+ Y+ Sbjct: 78 LGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVC 137 Query: 145 QPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIV 204 P + C P + LAAA I ++ +N V+ G+ VQ+IFT AK++ + +I++G+V Sbjct: 138 APFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLV 197 Query: 205 RLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIG 264 L QG + +F+NSFEG+ +VG I+LA Y+ L++Y GW+ LNY+TEE++NP RNLPL+I Sbjct: 198 LLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAII 257 Query: 265 ISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGL 324 I +P+VT YIL NV+Y+TV+ ++L S AVAVTF D++ +WI+PL VA S G Sbjct: 258 IGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAA 317 Query: 325 NASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINY 384 N + A RL +V REGH+ + I V R TP P+++F GI+A IY+ DI L+NY Sbjct: 318 NGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNY 377 Query: 385 YSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYS-DTINS 443 +SF+ W F GL+I+G + +R+ + RP+K+ V P++ L ++FLV P+ S T Sbjct: 378 FSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEY 437 Query: 444 LIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLE 497 L + LSGL FYFL + H + + ++I T +LQ+L V E D E Sbjct: 438 LYCVLFILSGLLFYFLFV----HYKFGWAQKISKPITMHLQMLMEVVPPEEDPE 487 >gi|33286430 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 isoform b [Homo sapiens] Length = 332 Score = 266 bits (679), Expect = 4e-71 Identities = 139/315 (44%), Positives = 205/315 (65%), Gaps = 10/315 (3%) Query: 202 GIVRLGQGASTHFE--NSFEGSSFA-VGDIALALYSALFSYSGWDTLNYVTEEIKNPERN 258 GIV++ +G E N+FE +G +ALA F+Y GW+ LNYVTEE+ +P +N Sbjct: 2 GIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKN 61 Query: 259 LPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVAL 318 LP +I IS+P+VT +Y+ NVAY T + +++LAS+AVAVTF +++ G+ WI+P+SVAL Sbjct: 62 LPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVAL 121 Query: 319 SCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDI 378 S FGG+N S+ +SRLFF G+REGHLP + MIHV+R TP+P+LLF I L+ L D+ Sbjct: 122 STFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDM 181 Query: 379 FQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYS 438 + LINY F + F G+++ GQ+ LRWK+PD PRP+K+++ FPI++ L FL+ L+S Sbjct: 182 YTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWS 241 Query: 439 DTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLED 498 + + IG+AI L+G+P YFL + +HK P + T Q +C+ V E++ Sbjct: 242 EPVVCGIGLAIMLTGVPVYFLGV-YWQHK-PKCFSDFIELLTLVSQKMCVVVYPEVERGS 299 Query: 499 GGE-----MPKQRDP 508 G E M +Q+ P Sbjct: 300 GTEEANEDMEEQQQP 314 >gi|71999149 solute carrier family 7, (cationic amino acid transporter, y+ system) member 13 [Homo sapiens] Length = 470 Score = 246 bits (629), Expect = 3e-65 Identities = 151/440 (34%), Positives = 243/440 (55%), Gaps = 11/440 (2%) Query: 29 EQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSA-SFGLSLVIWAVGGLFSVFGA 87 E+++LK+ G ++ N+IG+GIFVSPKGVL YS + G+SL +WA + ++ Sbjct: 5 EKIQLKRVFGYWWGTSFLLINIIGAGIFVSPKGVLAYSCMNVGVSLCVWAGCAILAMTST 64 Query: 88 LCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMVQPL 147 LC AE+ + SGA Y ++ FG +AF+ LWTSL + A A+ A Y +QP Sbjct: 65 LCSAEISISFPCSGAQYYFLKRYFGSTVAFLNLWTSLFLGSGVV-AGQALLLAEYSIQPF 123 Query: 148 FPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIVRLG 207 FPSC P + LA A + ++ + VK T +Q + KV L + + G+V L Sbjct: 124 FPSCSVPKLPKKCLALAMLWIVGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVVFLI 183 Query: 208 QGASTH---FENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIG 264 +G + F+N+F+ + + A++ F+YSG + E+K P +P I Sbjct: 184 RGKKENVERFQNAFDAELPDISHLIQAIFQGYFAYSGGACFTLIAGELKKPRTTIPKCIF 243 Query: 265 ISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGL 324 ++P+VT++Y+L N++Y TVL R+IL+SDAVA+T+AD+ F WI+P +++ S F L Sbjct: 244 TALPLVTVVYLLVNISYLTVLTPREILSSDAVAITWADRAFPSLAWIMPFAISTSLFSNL 303 Query: 325 NASIVAASRLFFVGSREGHLPDAICMI--HVERFTPVPSLLFNGIMALIYLCVEDIFQLI 382 SI +SR ++ S+EG LP + H FT V L+ G +A+I + + LI Sbjct: 304 LISIFKSSRPIYLASQEGQLPLLFNTLNSHSSPFTAVLLLVTLGSLAII---LTSLIDLI 360 Query: 383 NYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLY-SDTI 441 NY F+ + L ++G L R++EP+ P K+ + FP+ + + LV +PL S + Sbjct: 361 NYIFFTGSLWSILLMIGILRRRYQEPNLSIPYKVFLSFPLATIVIDVGLVVIPLVKSPNV 420 Query: 442 NSLIGIAIALSGLPFYFLII 461 + + + + LSGL FY +I Sbjct: 421 HYVYVLLLVLSGLLFYIPLI 440 >gi|110347453 solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 [Homo sapiens] Length = 635 Score = 101 bits (252), Expect = 1e-21 Identities = 90/406 (22%), Positives = 177/406 (43%), Gaps = 32/406 (7%) Query: 30 QVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALC 89 + L++ +S L+ L VG M+GSG++V G + + L+ + V + S+ ALC Sbjct: 30 ETSLRRCLSTLDLTLLGVGGMVGSGLYVLT-GAVAKEVAGPAVLLSFGVAAVASLLAALC 88 Query: 90 YAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLL--IIEPTSQAIIAITFANYMVQPL 147 YAE G + ++G++Y + + G AF+ W LL II A +A ++ Y+ + Sbjct: 89 YAEFGARVPRTGSAYLFTYVSMGELWAFLIGWNVLLEYII---GGAAVARAWSGYL-DSM 144 Query: 148 FPSCFAPYAASRL--------------LAAACICLLT-FINCAYVKWGTLVQDIFTYAKV 192 F + + + LAA I L + F++C + + + F+ + Sbjct: 145 FSHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCG-ARVSSWLNHTFSAISL 203 Query: 193 LALIAVIVAGIVRLGQGASTHFENSFEG--SSFAVGDIALALYSALFSYSGWDTLNYVTE 250 L ++ +++ G + A H ++ EG + F + S +++ G+D + +E Sbjct: 204 LVILFIVILGFIL----AQPHNWSADEGGFAPFGFSGVMAGTASCFYAFVGFDVIAASSE 259 Query: 251 EIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNW 310 E +NP R++PL+I IS+ I YIL + ++ + A+A F + + + Sbjct: 260 EAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGF 319 Query: 311 IIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMAL 370 I+ + L + + + R+ + + +G +H PV L G++ Sbjct: 320 IVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTA 379 Query: 371 IYLCVEDIFQLINYYSFS---YWFFVGLSIVGQLYLRWKEPDRPRP 413 + D+ L+ + S + FV SI+ + + P P P Sbjct: 380 FLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSSPPSSPGP 425 >gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo sapiens] Length = 658 Score = 92.4 bits (228), Expect = 9e-19 Identities = 97/414 (23%), Positives = 176/414 (42%), Gaps = 40/414 (9%) Query: 29 EQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVI-WAVGGLFSVFGA 87 E KL + +S ++ + L VG+ +G+G++V V A G S+V+ + + L SV Sbjct: 26 EDTKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVA--KADSGPSIVVSFLIAALASVMAG 83 Query: 88 LCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLL--IIEPTSQAII-AITFANYMV 144 LCYAE G + K+G++Y Y G AFI W +L +I +S A + TF + Sbjct: 84 LCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLS 143 Query: 145 QPL-------FPSCFAPYAASRLLAAACICLLTFINCAY-VKWGTLVQDIFTYAKVLALI 196 + + F + A A C+ LL ++ VK V +FT +L L+ Sbjct: 144 KQIGQFLRTYFRMNYTGLAEYPDFFAVCLILLLAGLLSFGVKESAWVNKVFTAVNILVLL 203 Query: 197 AVIVAGIVRLG------------------------QGASTHFENSFEGSSFAVGDIALAL 232 V+VAG V+ G S + F F G +A A Sbjct: 204 FVMVAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFT-GTLAGAA 262 Query: 233 YSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILA 292 + +++ G+D + EE++NP++ +P+ I S+ + + Y + A ++ + Sbjct: 263 -TCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDE 321 Query: 293 SDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIH 352 + V F +G +++ + L SI R+ + + +G L + I+ Sbjct: 322 KSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSIFPMPRVIYAMAEDGLLFKCLAQIN 381 Query: 353 VERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWK 406 + TP+ + L +G +A + + D+ L++ S L L LR++ Sbjct: 382 SKTKTPIIATLSSGAVAALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQ 435 >gi|4507047 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 [Homo sapiens] Length = 629 Score = 90.1 bits (222), Expect = 4e-18 Identities = 103/426 (24%), Positives = 182/426 (42%), Gaps = 55/426 (12%) Query: 29 EQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVI-WAVGGLFSVFGA 87 E+ +L + ++ + V L VG+ +G+G++V V +A G ++VI + + L SV Sbjct: 24 EETRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVARENA--GPAIVISFLIAALASVLAG 81 Query: 88 LCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLL--IIEPTSQA-IIAITFANYMV 144 LCY E G + K+G++Y Y G AFI W +L II +S A + TF + Sbjct: 82 LCYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIG 141 Query: 145 QPL------FPSCFAPYAASR---LLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLAL 195 +P+ + AP + + A I +LT + VK +V IFT VL L Sbjct: 142 RPIGEFSRTHMTLNAPGVLAENPDIFAVIIILILTGLLTLGVKESAMVNKIFTCINVLVL 201 Query: 196 IAVIVAGIVRLGQGASTHFENSFEGSS---------------------FAVGDIALALYS 234 ++V+G V+ E F +S F + + Sbjct: 202 GFIMVSGFVKGSVKNWQLTEEDFGNTSGRLCLNNDTKEGKPGVGGFMPFGFSGVLSGAAT 261 Query: 235 ALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYI-----LTNVAYYTVLDMRD 289 +++ G+D + EE+KNP++ +P+ I S+ I I Y LT + Y LD Sbjct: 262 CFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMPYFCLDNNS 321 Query: 290 ILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAA----SRLFFVGSREGHLP 345 L V + + +VA+ L+AS++ + R+ + + +G L Sbjct: 322 PLPDAFKHVGWEGAKY---------AVAVGSLCALSASLLGSMFPMPRVIYAMAEDGLLF 372 Query: 346 DAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRW 405 + ++ TP+ + L +G +A + + D+ L++ S L L LR+ Sbjct: 373 KFLANVNDRTKTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVAACVLVLRY 432 Query: 406 KEPDRP 411 +P++P Sbjct: 433 -QPEQP 437 >gi|114326550 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 [Homo sapiens] Length = 619 Score = 90.1 bits (222), Expect = 4e-18 Identities = 99/427 (23%), Positives = 172/427 (40%), Gaps = 57/427 (13%) Query: 27 GPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVI-WAVGGLFSVF 85 G + +L + +S L+ V L VG+ +G+G++V V A G S+VI + V L SV Sbjct: 22 GMAETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKA--GPSIVICFLVAALSSVL 79 Query: 86 GALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLL--IIEPTSQA-----IIAIT 138 LCYAE G + +SG++Y Y G AF W +L +I S A Sbjct: 80 AGLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNL 139 Query: 139 FANYMVQPL-------FPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAK 191 N++ + L P A Y A + LLT + LV +FT Sbjct: 140 IGNHISKTLQGSIALHVPHVLAEY--PDFFALGLVLLLTGLLALGASESALVTKVFTGVN 197 Query: 192 VLALIAVIVAGIVR----------------------------LGQGASTHFENSFEGSSF 223 +L L V+++G V+ LG G F FEG Sbjct: 198 LLVLGFVMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPF--GFEG--- 252 Query: 224 AVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYT 283 I + +++ G+D + EE +NP+R++P+ I IS+ + + Y + A Sbjct: 253 ----ILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTL 308 Query: 284 VLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGH 343 ++ + + F + +++ + + L S+ R+ + + +G Sbjct: 309 MMPYYQLQPESPLPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGL 368 Query: 344 LPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYL 403 L + IH TP+ + + +GI+A + + L++ S L + L L Sbjct: 369 LFRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLIL 428 Query: 404 RWKEPDR 410 R+ +PD+ Sbjct: 429 RY-QPDQ 434 >gi|114326544 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 [Homo sapiens] Length = 619 Score = 90.1 bits (222), Expect = 4e-18 Identities = 99/427 (23%), Positives = 172/427 (40%), Gaps = 57/427 (13%) Query: 27 GPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVI-WAVGGLFSVF 85 G + +L + +S L+ V L VG+ +G+G++V V A G S+VI + V L SV Sbjct: 22 GMAETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKA--GPSIVICFLVAALSSVL 79 Query: 86 GALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLL--IIEPTSQA-----IIAIT 138 LCYAE G + +SG++Y Y G AF W +L +I S A Sbjct: 80 AGLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNL 139 Query: 139 FANYMVQPL-------FPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAK 191 N++ + L P A Y A + LLT + LV +FT Sbjct: 140 IGNHISKTLQGSIALHVPHVLAEY--PDFFALGLVLLLTGLLALGASESALVTKVFTGVN 197 Query: 192 VLALIAVIVAGIVR----------------------------LGQGASTHFENSFEGSSF 223 +L L V+++G V+ LG G F FEG Sbjct: 198 LLVLGFVMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPF--GFEG--- 252 Query: 224 AVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYT 283 I + +++ G+D + EE +NP+R++P+ I IS+ + + Y + A Sbjct: 253 ----ILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTL 308 Query: 284 VLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGH 343 ++ + + F + +++ + + L S+ R+ + + +G Sbjct: 309 MMPYYQLQPESPLPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGL 368 Query: 344 LPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYL 403 L + IH TP+ + + +GI+A + + L++ S L + L L Sbjct: 369 LFRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLIL 428 Query: 404 RWKEPDR 410 R+ +PD+ Sbjct: 429 RY-QPDQ 434 >gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo sapiens] Length = 697 Score = 89.4 bits (220), Expect = 7e-18 Identities = 97/414 (23%), Positives = 177/414 (42%), Gaps = 41/414 (9%) Query: 29 EQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVI-WAVGGLFSVFGA 87 E KL + +S ++ + L VG+ +G+G++V V A G S+V+ + + L SV Sbjct: 66 EDTKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVA--KADSGPSIVVSFLIAALASVMAG 123 Query: 88 LCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLL--IIEPTSQAII-AITFANYMV 144 LCYAE G + K+G++Y Y G AFI W +L +I +S A + TF + Sbjct: 124 LCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLS 183 Query: 145 QPL-------FPSCFAPYAASRLLAAACICLLTFINCAY-VKWGTLVQDIFTYAKVLALI 196 + + F + A A C+ LL ++ VK V +FT +L L+ Sbjct: 184 KQIGQFLRTYFRMNYTGLAEYPDFFAVCLILLLAGLLSFGVKESAWVNKVFTAVNILVLL 243 Query: 197 AVIVAGIVRLG------------------------QGASTHFENSFEGSSFAVGDIALAL 232 V+VAG V+ G S + F F G +A A Sbjct: 244 FVMVAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFT-GTLAGAA 302 Query: 233 YSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILA 292 + +++ G+D + EE++NP++ +P+ I S+ + + Y + A ++ + Sbjct: 303 -TCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDE 361 Query: 293 SDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIH 352 + V F +G +++ + L S+ R+ F +R+G L + + Sbjct: 362 KSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVS 421 Query: 353 VERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWK 406 +R +PV + L G+++ + + D+ L++ S L L LR++ Sbjct: 422 -KRQSPVAATLTAGVISALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQ 474 >gi|181337167 solute carrier family 7 (cationic amino acid transporter, y+ system), member 14 [Homo sapiens] Length = 771 Score = 73.9 bits (180), Expect = 3e-13 Identities = 97/413 (23%), Positives = 167/413 (40%), Gaps = 66/413 (15%) Query: 32 KLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALCYA 91 KL + ++ ++ + L VG+ +G+G++V V A G+ +V + + + S+ +CYA Sbjct: 48 KLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGV-IVSFIIAAVASILSGVCYA 106 Query: 92 ELGTTIKKS-GASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMVQPLFPS 150 E G + K+ G++Y Y G F+AF W +L + +I + +F S Sbjct: 107 EFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLIL------EYLIGTAAGASALSSMFDS 160 Query: 151 CFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLAL-IAVIVAGIVRLGQG 209 A + SR +A + L L + +Y +LAL IAVIV IV LG Sbjct: 161 -LANHTISRWMADSVGTL-----------NGLGKGEESYPDLLALLIAVIVTIIVALGVK 208 Query: 210 ASTHFENSFEGSSFAV---------------------------GDIALALYSALFSYSGW 242 S F N + AV + + +++ G+ Sbjct: 209 NSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAEGQFLPHGWSGVLQGAATCFYAFIGF 268 Query: 243 DTLNYVTEEIKNPERNLPLSIGISMPI-----VTIIYILTNVAYYTVLDMRDILASDAVA 297 D + EE KNP ++P +I S+ I V++ ILT + Y +D L VA Sbjct: 269 DIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEMFVA 328 Query: 298 VTFADQIFGIFNWIIPLSVALSCFGGLNASIVAA----SRLFFVGSREGHLPDAICMIHV 353 F + VA+ GL S++ + R+ + + +G L + + Sbjct: 329 HGF---------YAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSS 379 Query: 354 ERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWK 406 TPV + + +G +A + + + LI S L V L LR++ Sbjct: 380 YTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQ 432 >gi|198041678 solute carrier family 12 (potassium-chloride transporter), member 5 isoform 1 [Homo sapiens] Length = 1139 Score = 33.5 bits (75), Expect = 0.47 Identities = 48/242 (19%), Positives = 101/242 (41%), Gaps = 19/242 (7%) Query: 251 EIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLD---MRDILASDAVAVTFADQIFGI 307 ++++ ++++P +++ + +YI + V + ++ +RD + Sbjct: 446 DLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWP 505 Query: 308 FNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVE-RFTPVPSLLFNG 366 W+I + S G S+ A RL SR+G +P H + P +LL Sbjct: 506 SPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLTA 565 Query: 367 I---MALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLR---WKEPDRPRPLKLSVFF 420 + ++ ++++ +++ + + FV L+ Q LR W+ R LS F Sbjct: 566 CICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLS-FL 624 Query: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480 + CL +F+ + +L+ + IA GL + ++ R E + +R + SA Sbjct: 625 GMSLCLALMFICS------WYYALVAMLIA--GLIYKYIEYRGAEKEWGDGIRGLSLSAA 676 Query: 481 RY 482 RY Sbjct: 677 RY 678 >gi|11968148 solute carrier family 12 (potassium-chloride transporter), member 5 isoform 2 [Homo sapiens] Length = 1116 Score = 33.5 bits (75), Expect = 0.47 Identities = 48/242 (19%), Positives = 101/242 (41%), Gaps = 19/242 (7%) Query: 251 EIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLD---MRDILASDAVAVTFADQIFGI 307 ++++ ++++P +++ + +YI + V + ++ +RD + Sbjct: 423 DLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWP 482 Query: 308 FNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVE-RFTPVPSLLFNG 366 W+I + S G S+ A RL SR+G +P H + P +LL Sbjct: 483 SPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLTA 542 Query: 367 I---MALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLR---WKEPDRPRPLKLSVFF 420 + ++ ++++ +++ + + FV L+ Q LR W+ R LS F Sbjct: 543 CICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLS-FL 601 Query: 421 PIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSAT 480 + CL +F+ + +L+ + IA GL + ++ R E + +R + SA Sbjct: 602 GMSLCLALMFICS------WYYALVAMLIA--GLIYKYIEYRGAEKEWGDGIRGLSLSAA 653 Query: 481 RY 482 RY Sbjct: 654 RY 655 >gi|34916028 solute carrier family 16 (monocarboxylic acid transporters), member 9 [Homo sapiens] Length = 509 Score = 31.6 bits (70), Expect = 1.8 Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 4/93 (4%) Query: 313 PLSVALSCFGGLNASIVAASRLFFVGSRE---GHLPDAICMIHVERFTPVPSLLFNGIMA 369 PL+V + L+A + +VGS G L +C + V F P +F+G M Sbjct: 30 PLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLASPVCSLCVSSFGARPVTIFSGFMV 89 Query: 370 LIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLY 402 L + I + FSY VGL G LY Sbjct: 90 AGGLMLSSFAPNIYFLFFSYGIVVGLG-CGLLY 121 >gi|219689113 two pore segment channel 1 isoform 1 [Homo sapiens] Length = 888 Score = 30.8 bits (68), Expect = 3.1 Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 6/51 (11%) Query: 437 YSDTINSLIGI-AIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVL 486 +S T+ + +G+ A+AL+ PFYF+++ RPL L R+ RY VL Sbjct: 584 FSVTVFAFLGLLALALNMEPFYFIVV-----LRPLQLLRLFKLKERYRNVL 629 >gi|29725622 two pore segment channel 1 isoform 2 [Homo sapiens] Length = 816 Score = 30.8 bits (68), Expect = 3.1 Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 6/51 (11%) Query: 437 YSDTINSLIGI-AIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVL 486 +S T+ + +G+ A+AL+ PFYF+++ RPL L R+ RY VL Sbjct: 512 FSVTVFAFLGLLALALNMEPFYFIVV-----LRPLQLLRLFKLKERYRNVL 557 >gi|41352721 solute carrier family 36 member 1 [Homo sapiens] Length = 476 Score = 30.4 bits (67), Expect = 4.0 Identities = 16/42 (38%), Positives = 27/42 (64%), Gaps = 1/42 (2%) Query: 234 SALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYI 275 +A+FS+ G + + ++K+P R PL + + M IVTI+YI Sbjct: 264 TAIFSFEGIGMVLPLENKMKDP-RKFPLILYLGMVIVTILYI 304 >gi|4759114 solute carrier family 16, member 4 [Homo sapiens] Length = 487 Score = 30.4 bits (67), Expect = 4.0 Identities = 28/101 (27%), Positives = 40/101 (39%), Gaps = 16/101 (15%) Query: 43 VCLIVGNMIGS--GIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALCYA--------- 91 +C I+G S G FV G LI S + + + +G L + A Y Sbjct: 80 ICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKY 139 Query: 92 -----ELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLII 127 L T I +SG ++L F FL + WT LI+ Sbjct: 140 FKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGALIL 180 >gi|36951034 G protein-coupled receptor 78 [Homo sapiens] Length = 363 Score = 30.4 bits (67), Expect = 4.0 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 26/93 (27%) Query: 135 IAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTL---------VQD 185 I I A +++ CFAPY +RL L+ F+ +WG L V D Sbjct: 243 IGIAIATFLI------CFAPYVMTRLAE-----LVPFVT-VNAQWGILSKCLTYSKAVAD 290 Query: 186 IFTYAKVLALIAVIVAGIV-----RLGQGASTH 213 FTY+ + ++AG+V R + ASTH Sbjct: 291 PFTYSLLRRPFRQVLAGMVHRLLKRTPRPASTH 323 >gi|166235895 ectonucleoside triphosphate diphosphohydrolase 6 isoform 2 [Homo sapiens] Length = 467 Score = 30.4 bits (67), Expect = 4.0 Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 6/78 (7%) Query: 184 QDI-FTYAKVLALIAVIVAGIVRL----GQGASTHFENSFEGSSFAVGDIALALYSALFS 238 QDI F + K L+ AG+ L Q + F+ S F VGD +++ + Sbjct: 148 QDIPFDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVFKASPFLVGDDCVSIMNGTDE 207 Query: 239 -YSGWDTLNYVTEEIKNP 255 S W T+N++T +K P Sbjct: 208 GVSAWITINFLTGSLKTP 225 >gi|166235893 ectonucleoside triphosphate diphosphohydrolase 6 isoform 1 [Homo sapiens] Length = 484 Score = 30.4 bits (67), Expect = 4.0 Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 6/78 (7%) Query: 184 QDI-FTYAKVLALIAVIVAGIVRL----GQGASTHFENSFEGSSFAVGDIALALYSALFS 238 QDI F + K L+ AG+ L Q + F+ S F VGD +++ + Sbjct: 165 QDIPFDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVFKASPFLVGDDCVSIMNGTDE 224 Query: 239 -YSGWDTLNYVTEEIKNP 255 S W T+N++T +K P Sbjct: 225 GVSAWITINFLTGSLKTP 242 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.327 0.142 0.433 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,055,071 Number of Sequences: 37866 Number of extensions: 773919 Number of successful extensions: 2123 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 23 Number of HSP's successfully gapped in prelim test: 12 Number of HSP's that attempted gapping in prelim test: 2047 Number of HSP's gapped (non-prelim): 42 length of query: 511 length of database: 18,247,518 effective HSP length: 107 effective length of query: 404 effective length of database: 14,195,856 effective search space: 5735125824 effective search space used: 5735125824 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.