Guide to the Human Genome
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Search of human proteins with 18677774

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18677774 palmitoyl-protein thioesterase 2 isoform a
precursor [Homo sapiens]
         (302 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18677774 palmitoyl-protein thioesterase 2 isoform a precursor...   636   0.0  
gi|20336251 palmitoyl-protein thioesterase 2 isoform b precursor...   636   0.0  
gi|4506031 palmitoyl-protein thioesterase 1 isoform 1 precursor ...    79   6e-15
gi|217272890 palmitoyl-protein thioesterase 1 isoform 2 precurso...    65   6e-11
gi|21618344 signal transducer and activator of transcription 5B ...    31   1.2  
gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precurs...    29   4.5  
gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precurs...    29   4.5  
gi|33942072 trinucleotide repeat containing 5 [Homo sapiens]           29   4.5  
gi|134031945 SCO-spondin [Homo sapiens]                                29   5.8  
gi|242117946 hypothetical protein LOC57579 isoform c [Homo sapiens]    28   7.6  
gi|157671939 hypothetical protein LOC57579 isoform b [Homo sapiens]    28   7.6  
gi|157671937 hypothetical protein LOC57579 isoform a [Homo sapiens]    28   7.6  
gi|46240862 GPI deacylase [Homo sapiens]                               28   7.6  
gi|68989256 ras inhibitor RIN1 [Homo sapiens]                          28   10.0 
gi|194272183 G protein-coupled receptor 124 [Homo sapiens]             28   10.0 

>gi|18677774 palmitoyl-protein thioesterase 2 isoform a precursor
           [Homo sapiens]
          Length = 302

 Score =  636 bits (1641), Expect = 0.0
 Identities = 302/302 (100%), Positives = 302/302 (100%)

Query: 1   MLGLWGQRLPAAWVLLLLPFLPLLLLAAPAPHRASYKPVIVVHGLFDSSYSFRHLLEYIN 60
           MLGLWGQRLPAAWVLLLLPFLPLLLLAAPAPHRASYKPVIVVHGLFDSSYSFRHLLEYIN
Sbjct: 1   MLGLWGQRLPAAWVLLLLPFLPLLLLAAPAPHRASYKPVIVVHGLFDSSYSFRHLLEYIN 60

Query: 61  ETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMAKAPQGVHLICYSQGGLVCRAL 120
           ETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMAKAPQGVHLICYSQGGLVCRAL
Sbjct: 61  ETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMAKAPQGVHLICYSQGGLVCRAL 120

Query: 121 LSVMDDHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFSICNYWH 180
           LSVMDDHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFSICNYWH
Sbjct: 121 LSVMDDHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFSICNYWH 180

Query: 181 DPHHDDLYLNASSFLALINGERDHPNATVWRKNFLRVGHLVLIGGPDDGVITPWQSSFFG 240
           DPHHDDLYLNASSFLALINGERDHPNATVWRKNFLRVGHLVLIGGPDDGVITPWQSSFFG
Sbjct: 181 DPHHDDLYLNASSFLALINGERDHPNATVWRKNFLRVGHLVLIGGPDDGVITPWQSSFFG 240

Query: 241 FYDANETVLEMEEQLVYLRDSFGLKTLLARGAIVRCPMAGISHTAWHSNRTLYETCIEPW 300
           FYDANETVLEMEEQLVYLRDSFGLKTLLARGAIVRCPMAGISHTAWHSNRTLYETCIEPW
Sbjct: 241 FYDANETVLEMEEQLVYLRDSFGLKTLLARGAIVRCPMAGISHTAWHSNRTLYETCIEPW 300

Query: 301 LS 302
           LS
Sbjct: 301 LS 302


>gi|20336251 palmitoyl-protein thioesterase 2 isoform b precursor
           [Homo sapiens]
          Length = 308

 Score =  636 bits (1641), Expect = 0.0
 Identities = 302/302 (100%), Positives = 302/302 (100%)

Query: 1   MLGLWGQRLPAAWVLLLLPFLPLLLLAAPAPHRASYKPVIVVHGLFDSSYSFRHLLEYIN 60
           MLGLWGQRLPAAWVLLLLPFLPLLLLAAPAPHRASYKPVIVVHGLFDSSYSFRHLLEYIN
Sbjct: 7   MLGLWGQRLPAAWVLLLLPFLPLLLLAAPAPHRASYKPVIVVHGLFDSSYSFRHLLEYIN 66

Query: 61  ETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMAKAPQGVHLICYSQGGLVCRAL 120
           ETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMAKAPQGVHLICYSQGGLVCRAL
Sbjct: 67  ETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMAKAPQGVHLICYSQGGLVCRAL 126

Query: 121 LSVMDDHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFSICNYWH 180
           LSVMDDHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFSICNYWH
Sbjct: 127 LSVMDDHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFSICNYWH 186

Query: 181 DPHHDDLYLNASSFLALINGERDHPNATVWRKNFLRVGHLVLIGGPDDGVITPWQSSFFG 240
           DPHHDDLYLNASSFLALINGERDHPNATVWRKNFLRVGHLVLIGGPDDGVITPWQSSFFG
Sbjct: 187 DPHHDDLYLNASSFLALINGERDHPNATVWRKNFLRVGHLVLIGGPDDGVITPWQSSFFG 246

Query: 241 FYDANETVLEMEEQLVYLRDSFGLKTLLARGAIVRCPMAGISHTAWHSNRTLYETCIEPW 300
           FYDANETVLEMEEQLVYLRDSFGLKTLLARGAIVRCPMAGISHTAWHSNRTLYETCIEPW
Sbjct: 247 FYDANETVLEMEEQLVYLRDSFGLKTLLARGAIVRCPMAGISHTAWHSNRTLYETCIEPW 306

Query: 301 LS 302
           LS
Sbjct: 307 LS 308


>gi|4506031 palmitoyl-protein thioesterase 1 isoform 1 precursor
           [Homo sapiens]
          Length = 306

 Score = 78.6 bits (192), Expect = 6e-15
 Identities = 81/292 (27%), Positives = 131/292 (44%), Gaps = 41/292 (14%)

Query: 10  PAAWVLLLLPFLP-------LLLLAAPAPHRASYKPVIVVHGLFDSS---YSFRHLLEYI 59
           P    LL +  LP       L  L  PAP      P+++ HG+ DS     S   + + +
Sbjct: 4   PGCLWLLAVALLPWTCASRALQHLDPPAP-----LPLVIWHGMGDSCCNPLSMGAIKKMV 58

Query: 60  NETHPGTVVTVLDLFDGRESLRPL----WEQVQGFREAVVPIMAKAP---QGVHLICYSQ 112
            +  PG  V  L++  G+  +  +    +  V      V   +AK P   QG + + +SQ
Sbjct: 59  EKKIPGIYVLSLEI--GKTLMEDVENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQ 116

Query: 113 GGLVCRALLSVMDDHNVDSFISLSSPQMGQYG------DTDYLKWLFPTSMRSNLYRICY 166
           GG   RA+        + + IS+     G +G      ++ ++       +R  L    Y
Sbjct: 117 GGQFLRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHIC----DFIRKTLNAGAY 172

Query: 167 SPWGQEFSI-CNYWHDPHHDDLYLNASSFLALINGERDHPNATVWRKNFLRVGHLVLIGG 225
           S   QE  +   YWHDP  +D+Y N S FLA IN ER    +  ++KN + +   V++  
Sbjct: 173 SKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINES--YKKNLMALKKFVMVKF 230

Query: 226 PDDGVITPWQSSFFGFY---DANETVLEMEEQLVYLRDSFGLKTLLARGAIV 274
            +D ++ P  S +FGFY    A ET+  ++E  +Y +D  GLK +   G +V
Sbjct: 231 LNDSIVDPVDSEWFGFYRSGQAKETI-PLQETSLYTQDRLGLKEMDNAGQLV 281


>gi|217272890 palmitoyl-protein thioesterase 1 isoform 2 precursor
           [Homo sapiens]
          Length = 203

 Score = 65.5 bits (158), Expect = 6e-11
 Identities = 43/122 (35%), Positives = 65/122 (53%), Gaps = 7/122 (5%)

Query: 157 MRSNLYRICYSPWGQEFSI-CNYWHDPHHDDLYLNASSFLALINGERDHPNATVWRKNFL 215
           +R  L    YS   QE  +   YWHDP  +D+Y N S FLA IN ER    +  ++KN +
Sbjct: 60  IRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINES--YKKNLM 117

Query: 216 RVGHLVLIGGPDDGVITPWQSSFFGFY---DANETVLEMEEQLVYLRDSFGLKTLLARGA 272
            +   V++   +D ++ P  S +FGFY    A ET+  ++E  +Y +D  GLK +   G 
Sbjct: 118 ALKKFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETI-PLQETSLYTQDRLGLKEMDNAGQ 176

Query: 273 IV 274
           +V
Sbjct: 177 LV 178


>gi|21618344 signal transducer and activator of transcription 5B
           [Homo sapiens]
          Length = 787

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 39/160 (24%), Positives = 65/160 (40%), Gaps = 35/160 (21%)

Query: 39  VIVVHGLFDSSYSFRHLLEYIN----------ETHPGTVVTVLDLFDG-----RESLRPL 83
           V +   LF++S S  HL +Y            E  PG   T    FDG     ++ L+P 
Sbjct: 531 VFLAQKLFNNSSS--HLEDYSGLSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPH 588

Query: 84  WEQ--VQGF--REAVVPIMAKAPQGVHLICYSQ---GGLVC--------RALLSVMDDHN 128
           W    + GF  ++    ++   P G  L+ +S    GG+          R   ++M    
Sbjct: 589 WNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSQERMFWNLMPFTT 648

Query: 129 VDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSP 168
            D  I   + ++G   D +YL ++FP   +  +Y   Y+P
Sbjct: 649 RDFSIRSLADRLG---DLNYLIYVFPDRPKDEVYSKYYTP 685


>gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precursor
           [Homo sapiens]
          Length = 878

 Score = 29.3 bits (64), Expect = 4.5
 Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 8/59 (13%)

Query: 113 GGLVCRALLSVMDDHNVDSFISLSSP--QMGQYGDTDYLK-WLFPTSMRSNLYRICYSP 168
           GG  CR   S   D     F   SSP  Q+   G   Y++  L PT  +S+ YR C+SP
Sbjct: 727 GGQCCRRQDSPSPD-----FYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSP 780


>gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precursor
           [Homo sapiens]
          Length = 944

 Score = 29.3 bits (64), Expect = 4.5
 Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 8/59 (13%)

Query: 113 GGLVCRALLSVMDDHNVDSFISLSSP--QMGQYGDTDYLK-WLFPTSMRSNLYRICYSP 168
           GG  CR   S   D     F   SSP  Q+   G   Y++  L PT  +S+ YR C+SP
Sbjct: 727 GGQCCRRQDSPSPD-----FYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSP 780


>gi|33942072 trinucleotide repeat containing 5 [Homo sapiens]
          Length = 278

 Score = 29.3 bits (64), Expect = 4.5
 Identities = 15/22 (68%), Positives = 16/22 (72%)

Query: 10 PAAWVLLLLPFLPLLLLAAPAP 31
          PA+  LLLLP L LLLL  PAP
Sbjct: 7  PASRCLLLLPLLLLLLLLLPAP 28


>gi|134031945 SCO-spondin [Homo sapiens]
          Length = 5147

 Score = 28.9 bits (63), Expect = 5.8
 Identities = 27/92 (29%), Positives = 36/92 (39%), Gaps = 21/92 (22%)

Query: 143  YGDTDYLKWLFPTSMRSNLYRICYSPWGQEFSICNYW-HDPHHDDLYLNASSFLALINGE 201
            + D D   W F   +++   R+              W HD HH D+ L       L+  E
Sbjct: 2184 WDDLDPAVWTFGRMVQARFVRV--------------WPHDVHHSDVPLQVE----LLGCE 2225

Query: 202  RDHPNATVWRKNFLRV--GHLVLIGGPDDGVI 231
               P A +     LR   G  VL GGP DGV+
Sbjct: 2226 PGSPPAPLCPGVGLRCASGECVLRGGPCDGVL 2257


>gi|242117946 hypothetical protein LOC57579 isoform c [Homo sapiens]
          Length = 1515

 Score = 28.5 bits (62), Expect = 7.6
 Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 18/116 (15%)

Query: 39   VIVVHGLFDSSYSFRHLLEYINETHPGTVVTVL-------DLFDGRESL--RPLWEQVQG 89
            ++ VHGL  +S   R +  YI    PG  +  L       D F   +S+  R L E +Q 
Sbjct: 1251 IVCVHGLDGNSADLRLVKTYIELGLPGGRIDFLMSERNQNDTFADFDSMTDRLLDEIIQ- 1309

Query: 90   FREAVVPIMAKAPQGVHLICYSQGGLVCRALLS----VMDDHNVDSFISLSSPQMG 141
                 + I +     +  I +S G L+ R++L+        + + +F+SLS P +G
Sbjct: 1310 ----YIQIYSLTVSKISFIGHSLGNLIIRSVLTRPRFKYYLNKLHTFLSLSGPHLG 1361


>gi|157671939 hypothetical protein LOC57579 isoform b [Homo sapiens]
          Length = 1302

 Score = 28.5 bits (62), Expect = 7.6
 Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 18/116 (15%)

Query: 39   VIVVHGLFDSSYSFRHLLEYINETHPGTVVTVL-------DLFDGRESL--RPLWEQVQG 89
            ++ VHGL  +S   R +  YI    PG  +  L       D F   +S+  R L E +Q 
Sbjct: 1038 IVCVHGLDGNSADLRLVKTYIELGLPGGRIDFLMSERNQNDTFADFDSMTDRLLDEIIQ- 1096

Query: 90   FREAVVPIMAKAPQGVHLICYSQGGLVCRALLS----VMDDHNVDSFISLSSPQMG 141
                 + I +     +  I +S G L+ R++L+        + + +F+SLS P +G
Sbjct: 1097 ----YIQIYSLTVSKISFIGHSLGNLIIRSVLTRPRFKYYLNKLHTFLSLSGPHLG 1148


>gi|157671937 hypothetical protein LOC57579 isoform a [Homo sapiens]
          Length = 1319

 Score = 28.5 bits (62), Expect = 7.6
 Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 18/116 (15%)

Query: 39   VIVVHGLFDSSYSFRHLLEYINETHPGTVVTVL-------DLFDGRESL--RPLWEQVQG 89
            ++ VHGL  +S   R +  YI    PG  +  L       D F   +S+  R L E +Q 
Sbjct: 1055 IVCVHGLDGNSADLRLVKTYIELGLPGGRIDFLMSERNQNDTFADFDSMTDRLLDEIIQ- 1113

Query: 90   FREAVVPIMAKAPQGVHLICYSQGGLVCRALLS----VMDDHNVDSFISLSSPQMG 141
                 + I +     +  I +S G L+ R++L+        + + +F+SLS P +G
Sbjct: 1114 ----YIQIYSLTVSKISFIGHSLGNLIIRSVLTRPRFKYYLNKLHTFLSLSGPHLG 1165


>gi|46240862 GPI deacylase [Homo sapiens]
          Length = 922

 Score = 28.5 bits (62), Expect = 7.6
 Identities = 13/23 (56%), Positives = 18/23 (78%)

Query: 101 APQGVHLICYSQGGLVCRALLSV 123
           AP+ V +I +S GGLV RALL++
Sbjct: 164 APKSVAIIGHSMGGLVARALLTL 186


>gi|68989256 ras inhibitor RIN1 [Homo sapiens]
          Length = 783

 Score = 28.1 bits (61), Expect = 10.0
 Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 10/74 (13%)

Query: 64  PGTVVTVLDLFDGRESL---RPLWEQVQGFREAVVPIMAKAPQGVHLICYSQGGLVCRAL 120
           PG VV++      RE L   RP+W Q+Q    A + ++   P G  L+  S     C+AL
Sbjct: 52  PGRVVSL------RERLLLTRPVWLQLQANAAAALHMLRTEPPGTFLVRKS-NTRQCQAL 104

Query: 121 LSVMDDHNVDSFIS 134
              + + +  SF+S
Sbjct: 105 CMRLPEASGPSFVS 118


>gi|194272183 G protein-coupled receptor 124 [Homo sapiens]
          Length = 1338

 Score = 28.1 bits (61), Expect = 10.0
 Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 1/41 (2%)

Query: 2  LGLWGQRLPAAWVLLLLPFLP-LLLLAAPAPHRASYKPVIV 41
          +G  G+R+  A   LLLP LP LLLL AP    A   P+ +
Sbjct: 1  MGAGGRRMRGAPARLLLPLLPWLLLLLAPEARGAPGCPLSI 41


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.140    0.463 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,525,345
Number of Sequences: 37866
Number of extensions: 559304
Number of successful extensions: 1420
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1410
Number of HSP's gapped (non-prelim): 17
length of query: 302
length of database: 18,247,518
effective HSP length: 102
effective length of query: 200
effective length of database: 14,385,186
effective search space: 2877037200
effective search space used: 2877037200
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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