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Search of human proteins with 18450369
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18450369 protein tyrosine phosphatase, receptor type, A
isoform 2 precursor [Homo sapiens]
(793 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18450371 protein tyrosine phosphatase, receptor type, A isofo... 1612 0.0
gi|18450369 protein tyrosine phosphatase, receptor type, A isofo... 1612 0.0
gi|4506303 protein tyrosine phosphatase, receptor type, A isofor... 1604 0.0
gi|5729993 protein tyrosine phosphatase, receptor type, E isofor... 941 0.0
gi|18860859 protein tyrosine phosphatase, receptor type, E isofo... 924 0.0
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 609 e-174
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 609 e-174
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 601 e-172
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 601 e-172
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 601 e-172
gi|18860894 protein tyrosine phosphatase, receptor type, D isofo... 601 e-172
gi|104487002 protein tyrosine phosphatase, receptor type, D isof... 598 e-171
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ... 589 e-168
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 589 e-168
gi|104487295 protein tyrosine phosphatase, receptor type, sigma ... 589 e-168
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 587 e-167
gi|18641364 protein tyrosine phosphatase, receptor type, C isofo... 471 e-132
gi|18641347 protein tyrosine phosphatase, receptor type, C isofo... 471 e-132
gi|18641362 protein tyrosine phosphatase, receptor type, C isofo... 471 e-132
gi|18860902 protein tyrosine phosphatase, receptor type, K isofo... 441 e-123
gi|157419150 protein tyrosine phosphatase, receptor type, M isof... 440 e-123
gi|157419152 protein tyrosine phosphatase, receptor type, M isof... 440 e-123
gi|208431815 protein tyrosine phosphatase, receptor type, K isof... 435 e-122
gi|148539860 protein tyrosine phosphatase, receptor type, T isof... 434 e-121
gi|148539858 protein tyrosine phosphatase, receptor type, T isof... 434 e-121
gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1 p... 408 e-113
gi|194097398 protein tyrosine phosphatase, receptor type, G prec... 404 e-112
gi|110735404 protein tyrosine phosphatase, receptor type, U isof... 404 e-112
gi|110735402 protein tyrosine phosphatase, receptor type, U isof... 404 e-112
gi|110735406 protein tyrosine phosphatase, receptor type, U isof... 398 e-110
>gi|18450371 protein tyrosine phosphatase, receptor type, A isoform
2 precursor [Homo sapiens]
Length = 793
Score = 1612 bits (4174), Expect = 0.0
Identities = 793/793 (100%), Positives = 793/793 (100%)
Query: 1 MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS 60
MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS
Sbjct: 1 MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS 60
Query: 61 VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP 120
VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP
Sbjct: 61 VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP 120
Query: 121 WEGNSSTAATTPETFPPSDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNS 180
WEGNSSTAATTPETFPPSDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNS
Sbjct: 121 WEGNSSTAATTPETFPPSDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNS 180
Query: 181 FRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALP 240
FRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALP
Sbjct: 181 FRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALP 240
Query: 241 ACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNK 300
ACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNK
Sbjct: 241 ACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNK 300
Query: 301 FIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSV 360
FIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSV
Sbjct: 301 FIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSV 360
Query: 361 EDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKA 420
EDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKA
Sbjct: 361 EDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKA 420
Query: 421 CNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDM 480
CNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDM
Sbjct: 421 CNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDM 480
Query: 481 QYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDK 540
QYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDK
Sbjct: 481 QYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDK 540
Query: 541 MRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGP 600
MRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGP
Sbjct: 541 MRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGP 600
Query: 601 LLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECE 660
LLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECE
Sbjct: 601 LLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECE 660
Query: 661 SYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPIT 720
SYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPIT
Sbjct: 661 SYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPIT 720
Query: 721 VHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQ 780
VHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQ
Sbjct: 721 VHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQ 780
Query: 781 EYIDAFSDYANFK 793
EYIDAFSDYANFK
Sbjct: 781 EYIDAFSDYANFK 793
>gi|18450369 protein tyrosine phosphatase, receptor type, A isoform
2 precursor [Homo sapiens]
Length = 793
Score = 1612 bits (4174), Expect = 0.0
Identities = 793/793 (100%), Positives = 793/793 (100%)
Query: 1 MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS 60
MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS
Sbjct: 1 MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS 60
Query: 61 VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP 120
VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP
Sbjct: 61 VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP 120
Query: 121 WEGNSSTAATTPETFPPSDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNS 180
WEGNSSTAATTPETFPPSDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNS
Sbjct: 121 WEGNSSTAATTPETFPPSDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNS 180
Query: 181 FRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALP 240
FRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALP
Sbjct: 181 FRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALP 240
Query: 241 ACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNK 300
ACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNK
Sbjct: 241 ACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNK 300
Query: 301 FIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSV 360
FIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSV
Sbjct: 301 FIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSV 360
Query: 361 EDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKA 420
EDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKA
Sbjct: 361 EDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKA 420
Query: 421 CNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDM 480
CNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDM
Sbjct: 421 CNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDM 480
Query: 481 QYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDK 540
QYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDK
Sbjct: 481 QYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDK 540
Query: 541 MRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGP 600
MRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGP
Sbjct: 541 MRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGP 600
Query: 601 LLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECE 660
LLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECE
Sbjct: 601 LLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECE 660
Query: 661 SYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPIT 720
SYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPIT
Sbjct: 661 SYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPIT 720
Query: 721 VHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQ 780
VHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQ
Sbjct: 721 VHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQ 780
Query: 781 EYIDAFSDYANFK 793
EYIDAFSDYANFK
Sbjct: 781 EYIDAFSDYANFK 793
>gi|4506303 protein tyrosine phosphatase, receptor type, A isoform 1
precursor [Homo sapiens]
Length = 802
Score = 1604 bits (4154), Expect = 0.0
Identities = 793/802 (98%), Positives = 793/802 (98%), Gaps = 9/802 (1%)
Query: 1 MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS 60
MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS
Sbjct: 1 MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS 60
Query: 61 VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP 120
VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP
Sbjct: 61 VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP 120
Query: 121 WEGNSSTAATTPETFPPS---------DETPIIAVMVALSSLLVIVFIIIVLYMLRFKKY 171
WEGNSSTAATTPETFPPS DETPIIAVMVALSSLLVIVFIIIVLYMLRFKKY
Sbjct: 121 WEGNSSTAATTPETFPPSGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKY 180
Query: 172 KQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKL 231
KQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKL
Sbjct: 181 KQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKL 240
Query: 232 FREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASF 291
FREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASF
Sbjct: 241 FREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASF 300
Query: 292 INGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCW 351
INGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCW
Sbjct: 301 INGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCW 360
Query: 352 TYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGM 411
TYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGM
Sbjct: 361 TYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGM 420
Query: 412 LKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ 471
LKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ
Sbjct: 421 LKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ 480
Query: 472 RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL 531
RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL
Sbjct: 481 RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL 540
Query: 532 TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQK 591
TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQK
Sbjct: 541 TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQK 600
Query: 592 DSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITV 651
DSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITV
Sbjct: 601 DSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITV 660
Query: 652 ELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQ 711
ELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQ
Sbjct: 661 ELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQ 720
Query: 712 QQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ 771
QQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ
Sbjct: 721 QQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ 780
Query: 772 YEFCYKVVQEYIDAFSDYANFK 793
YEFCYKVVQEYIDAFSDYANFK
Sbjct: 781 YEFCYKVVQEYIDAFSDYANFK 802
>gi|5729993 protein tyrosine phosphatase, receptor type, E isoform 1
precursor [Homo sapiens]
Length = 700
Score = 941 bits (2431), Expect = 0.0
Identities = 464/682 (68%), Positives = 558/682 (81%), Gaps = 14/682 (2%)
Query: 123 GNSSTA---ATTPETFPPSD--ETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSH 177
GN +TA TT + PP P++A ++ L LL+++ +++ Y RF+K ++A
Sbjct: 22 GNETTADSNETTTTSGPPDPGASQPLLAWLL-LPLLLLLLVLLLAAYFFRFRKQRKAVVS 80
Query: 178 SNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFN 237
++ ++ NG E+ E Q V LL+RSPS +KY P+PV+ LEEEI R ADD K FREEFN
Sbjct: 81 TSDKKMPNGILEEQEQQRVMLLSRSPSGPKKYFPIPVEHLEEEIRIRSADDCKQFREEFN 140
Query: 238 ALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQE 297
+LP+ IQ T E A+KEEN+EKNRY NILP DHSRV L+ ++G+P SDYINAS+I+GY+E
Sbjct: 141 SLPSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLDGIPCSDYINASYIDGYKE 200
Query: 298 KNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIR 357
KNKFIAAQGPK+ETVNDFWRM+WEQ +ATIVM+TNLKERKE KC QYWPDQGCWTYGNIR
Sbjct: 201 KNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERKEEKCHQYWPDQGCWTYGNIR 260
Query: 358 VSVEDVTVLVDYTVRKFCIQ-QVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLK 416
V VED VLVDYT+RKFCIQ Q+ D K RL++Q HFTSWPDFGVPFTPIGMLKFLK
Sbjct: 261 VCVEDCVVLVDYTIRKFCIQPQLPD--GCKAPRLVSQLHFTSWPDFGVPFTPIGMLKFLK 318
Query: 417 KVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMV 476
KVK NP +AG IVVHCSAGVGRTGTF+VIDAM+ MMH E+KVDV+ FVSRIR QR QMV
Sbjct: 319 KVKTLNPVHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQKVDVFEFVSRIRNQRPQMV 378
Query: 477 QTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKI 536
QTDMQY FIYQALLE+YLYGDTEL+V+SLE HLQ ++ GLEEEF+KLT+++I
Sbjct: 379 QTDMQYTFIYQALLEYYLYGDTELDVSSLEKHLQTMHGTTTHFDKIGLEEEFRKLTNVRI 438
Query: 537 QNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIA 596
+ MRTGNLPANMKK RV+QIIPY+FNRVI+ +KRG+E TDY+NASFIDGYRQKD +IA
Sbjct: 439 MKENMRTGNLPANMKKARVIQIIPYDFNRVILSMKRGQEYTDYINASFIDGYRQKDYFIA 498
Query: 597 SQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKE 656
+QGPL HT+EDFWRMIWEWKS +IVMLTE++ER Q+KC QYWP++G V++G+IT+E+K +
Sbjct: 499 TQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPTEGSVTHGEITIEIKND 558
Query: 657 EECESYTVRDLLVT-----NTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQ 711
E+ ++RD LVT +E + R +RQFHFHGWPE+GIP++GKGMI +IAAVQKQQ
Sbjct: 559 TLSEAISIRDFLVTLNQPQARQEEQVRVVRQFHFHGWPEIGIPAEGKGMIDLIAAVQKQQ 618
Query: 712 QQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ 771
QQ+GNHPITVHCSAGAGRTGTF ALS +LERVKAEG+LDVFQ VKSLRLQRPHMVQTLEQ
Sbjct: 619 QQTGNHPITVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQRPHMVQTLEQ 678
Query: 772 YEFCYKVVQEYIDAFSDYANFK 793
YEFCYKVVQ++ID FSDYANFK
Sbjct: 679 YEFCYKVVQDFIDIFSDYANFK 700
>gi|18860859 protein tyrosine phosphatase, receptor type, E isoform
2 [Homo sapiens]
Length = 642
Score = 924 bits (2387), Expect = 0.0
Identities = 449/632 (71%), Positives = 531/632 (84%), Gaps = 8/632 (1%)
Query: 168 FKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMAD 227
F+K ++A ++ ++ NG E+ E Q V LL+RSPS +KY P+PV+ LEEEI R AD
Sbjct: 13 FRKQRKAVVSTSDKKMPNGILEEQEQQRVMLLSRSPSGPKKYFPIPVEHLEEEIRIRSAD 72
Query: 228 DNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYI 287
D K FREEFN+LP+ IQ T E A+KEEN+EKNRY NILP DHSRV L+ ++G+P SDYI
Sbjct: 73 DCKQFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLDGIPCSDYI 132
Query: 288 NASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD 347
NAS+I+GY+EKNKFIAAQGPK+ETVNDFWRM+WEQ +ATIVM+TNLKERKE KC QYWPD
Sbjct: 133 NASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERKEEKCHQYWPD 192
Query: 348 QGCWTYGNIRVSVEDVTVLVDYTVRKFCIQ-QVGDMTNRKPQRLITQFHFTSWPDFGVPF 406
QGCWTYGNIRV VED VLVDYT+RKFCIQ Q+ D K RL++Q HFTSWPDFGVPF
Sbjct: 193 QGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPQLPD--GCKAPRLVSQLHFTSWPDFGVPF 250
Query: 407 TPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVS 466
TPIGMLKFLKKVK NP +AG IVVHCSAGVGRTGTF+VIDAM+ MMH E+KVDV+ FVS
Sbjct: 251 TPIGMLKFLKKVKTLNPVHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQKVDVFEFVS 310
Query: 467 RIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEE 526
RIR QR QMVQTDMQY FIYQALLE+YLYGDTEL+V+SLE HLQ ++ GLEE
Sbjct: 311 RIRNQRPQMVQTDMQYTFIYQALLEYYLYGDTELDVSSLEKHLQTMHGTTTHFDKIGLEE 370
Query: 527 EFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFID 586
EF+KLT+++I + MRTGNLPANMKK RV+QIIPY+FNRVI+ +KRG+E TDY+NASFID
Sbjct: 371 EFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVILSMKRGQEYTDYINASFID 430
Query: 587 GYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSY 646
GYRQKD +IA+QGPL HT+EDFWRMIWEWKS +IVMLTE++ER Q+KC QYWP++G V++
Sbjct: 431 GYRQKDYFIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPTEGSVTH 490
Query: 647 GDITVELKKEEECESYTVRDLLVT-----NTRENKSRQIRQFHFHGWPEVGIPSDGKGMI 701
G+IT+E+K + E+ ++RD LVT +E + R +RQFHFHGWPE+GIP++GKGMI
Sbjct: 491 GEITIEIKNDTLSEAISIRDFLVTLNQPQARQEEQVRVVRQFHFHGWPEIGIPAEGKGMI 550
Query: 702 SIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQ 761
+IAAVQKQQQQ+GNHPITVHCSAGAGRTGTF ALS +LERVKAEG+LDVFQ VKSLRLQ
Sbjct: 551 DLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQ 610
Query: 762 RPHMVQTLEQYEFCYKVVQEYIDAFSDYANFK 793
RPHMVQTLEQYEFCYKVVQ++ID FSDYANFK
Sbjct: 611 RPHMVQTLEQYEFCYKVVQDFIDIFSDYANFK 642
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 609 bits (1570), Expect = e-174
Identities = 314/644 (48%), Positives = 421/644 (65%), Gaps = 12/644 (1%)
Query: 153 LLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDV-----EPQSVPLLARSPSTNR 207
L VI+ I+IV+ +L FK+ K+ S S+ S G + + +P + L R
Sbjct: 1269 LAVILIILIVIAILLFKR-KRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGMR 1327
Query: 208 KYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILP 267
+PP+P+ L + I R A+D F +E+ ++ Q T E ++ E NK KNRY N++
Sbjct: 1328 DHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQ-QFTWENSNLEVNKPKNRYANVIA 1386
Query: 268 YDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATI 327
YDHSRV LT ++GVP SDYINA++I+GY+++N +IA QGP ET+ DFWRM+WEQ TAT+
Sbjct: 1387 YDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATV 1446
Query: 328 VMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKP 387
VM+T L+E+ KC QYWP +G T G I+V++ D L YTVR F + + G R+
Sbjct: 1447 VMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRE- 1505
Query: 388 QRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVID 447
+ QF F +WPD GVP P +L FL++VKACNP AG +VVHCSAGVGRTG F+VID
Sbjct: 1506 ---LRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVID 1562
Query: 448 AMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLET 507
AML+ M E+ VD+YG V+ +R+QR MVQT+ QYVFI++ALLE G TE+ +L
Sbjct: 1563 AMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYA 1622
Query: 508 HLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVI 567
H+QK+ PG S +E EFK L S K + + NLP N KNR++ I+PYE RV
Sbjct: 1623 HIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVC 1682
Query: 568 IPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELE 627
+ RG E +DY+NASF+DGYRQ+ +YIA+QGPL + EDFWRM+WE S IVMLT+L
Sbjct: 1683 LQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLR 1742
Query: 628 ERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHG 687
E G+EKC QYWP++ Y V+ E Y +R+ VT+ R+ +SR IRQF F
Sbjct: 1743 EMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTD 1802
Query: 688 WPEVGIPSDGKGMISIIAAVQKQQQQSG-NHPITVHCSAGAGRTGTFCALSTVLERVKAE 746
WPE G+P G+G I I V K ++Q G + PITVHCSAG GRTG F LS VLER++ E
Sbjct: 1803 WPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYE 1862
Query: 747 GILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYA 790
G++D+FQTVK+LR QRP MVQT +QY+ CY+ EY+ +F YA
Sbjct: 1863 GVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA 1906
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 609 bits (1570), Expect = e-174
Identities = 314/644 (48%), Positives = 421/644 (65%), Gaps = 12/644 (1%)
Query: 153 LLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDV-----EPQSVPLLARSPSTNR 207
L VI+ I+IV+ +L FK+ K+ S S+ S G + + +P + L R
Sbjct: 1260 LAVILIILIVIAILLFKR-KRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGMR 1318
Query: 208 KYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILP 267
+PP+P+ L + I R A+D F +E+ ++ Q T E ++ E NK KNRY N++
Sbjct: 1319 DHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQ-QFTWENSNLEVNKPKNRYANVIA 1377
Query: 268 YDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATI 327
YDHSRV LT ++GVP SDYINA++I+GY+++N +IA QGP ET+ DFWRM+WEQ TAT+
Sbjct: 1378 YDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATV 1437
Query: 328 VMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKP 387
VM+T L+E+ KC QYWP +G T G I+V++ D L YTVR F + + G R+
Sbjct: 1438 VMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRE- 1496
Query: 388 QRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVID 447
+ QF F +WPD GVP P +L FL++VKACNP AG +VVHCSAGVGRTG F+VID
Sbjct: 1497 ---LRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVID 1553
Query: 448 AMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLET 507
AML+ M E+ VD+YG V+ +R+QR MVQT+ QYVFI++ALLE G TE+ +L
Sbjct: 1554 AMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYA 1613
Query: 508 HLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVI 567
H+QK+ PG S +E EFK L S K + + NLP N KNR++ I+PYE RV
Sbjct: 1614 HIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVC 1673
Query: 568 IPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELE 627
+ RG E +DY+NASF+DGYRQ+ +YIA+QGPL + EDFWRM+WE S IVMLT+L
Sbjct: 1674 LQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLR 1733
Query: 628 ERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHG 687
E G+EKC QYWP++ Y V+ E Y +R+ VT+ R+ +SR IRQF F
Sbjct: 1734 EMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTD 1793
Query: 688 WPEVGIPSDGKGMISIIAAVQKQQQQSG-NHPITVHCSAGAGRTGTFCALSTVLERVKAE 746
WPE G+P G+G I I V K ++Q G + PITVHCSAG GRTG F LS VLER++ E
Sbjct: 1794 WPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYE 1853
Query: 747 GILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYA 790
G++D+FQTVK+LR QRP MVQT +QY+ CY+ EY+ +F YA
Sbjct: 1854 GVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA 1897
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 601 bits (1550), Expect = e-172
Identities = 311/679 (45%), Positives = 428/679 (63%), Gaps = 18/679 (2%)
Query: 125 SSTAATTPETFP----PSDETPII----AVMVALSSLLVIVFIIIVLYMLRFKKYKQAGS 176
S AT+P + P D PI ++ + +L +VFII ++ + K K+A S
Sbjct: 1238 SKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRKRAES 1297
Query: 177 HSNSFRLSNGRT----EDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLF 232
S + N + +P + L +PP+P+ +L + I R A+DN F
Sbjct: 1298 DSRKSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKF 1357
Query: 233 REEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFI 292
+E+ ++ Q T E ++ E NK KNRY N++ YDHSRV L+ +EG+P SDY+NA++I
Sbjct: 1358 SQEYESIDPGQ-QFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYI 1416
Query: 293 NGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWT 352
+GY+++N +IA QG ET DFWRMIWEQ +AT+VM+T L+ER KC QYWP +G T
Sbjct: 1417 DGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTET 1476
Query: 353 YGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGML 412
+G ++V++ D L Y VR F + + G R+ + QF FT+WPD GVP P L
Sbjct: 1477 HGLVQVTLLDTVELATYCVRTFALYKNGSSEKRE----VRQFQFTAWPDHGVPEHPTPFL 1532
Query: 413 KFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQR 472
FL++VK CNP AG +VVHCSAGVGRTG F+VIDAML+ + E+ VD+YG V+ +RAQR
Sbjct: 1533 AFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQR 1592
Query: 473 CQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLT 532
MVQT+ QY+FI+ ALLE G+TE+ +L ++QK+ G + G+E EFK+L
Sbjct: 1593 NYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLA 1652
Query: 533 SIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKD 592
S K + + NLP N KNR++ I+PYE RV + RG E +DY+NASFIDGYRQ+
Sbjct: 1653 SSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQK 1712
Query: 593 SYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVE 652
+YIA+QGPL T EDFWRM+WE S +VMLT+L E G+EKC QYWP++ Y V+
Sbjct: 1713 AYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVD 1772
Query: 653 LKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQ 712
E Y +R+ VT+ R+ +SR +RQF F WPE G+P G+G I I V K ++
Sbjct: 1773 PMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKE 1832
Query: 713 QSG-NHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ 771
Q G + PI+VHCSAG GRTG F LS VLER++ EG++D+FQTVK LR QRP MVQT +Q
Sbjct: 1833 QFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQ 1892
Query: 772 YEFCYKVVQEYIDAFSDYA 790
Y+F Y+ EY+ +F YA
Sbjct: 1893 YQFSYRAALEYLGSFDHYA 1911
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform 2
precursor [Homo sapiens]
Length = 1899
Score = 601 bits (1550), Expect = e-172
Identities = 311/679 (45%), Positives = 428/679 (63%), Gaps = 18/679 (2%)
Query: 125 SSTAATTPETFP----PSDETPII----AVMVALSSLLVIVFIIIVLYMLRFKKYKQAGS 176
S AT+P + P D PI ++ + +L +VFII ++ + K K+A S
Sbjct: 1225 SKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRKRAES 1284
Query: 177 HSNSFRLSNGRT----EDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLF 232
S + N + +P + L +PP+P+ +L + I R A+DN F
Sbjct: 1285 DSRKSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKF 1344
Query: 233 REEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFI 292
+E+ ++ Q T E ++ E NK KNRY N++ YDHSRV L+ +EG+P SDY+NA++I
Sbjct: 1345 SQEYESIDPGQ-QFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYI 1403
Query: 293 NGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWT 352
+GY+++N +IA QG ET DFWRMIWEQ +AT+VM+T L+ER KC QYWP +G T
Sbjct: 1404 DGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTET 1463
Query: 353 YGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGML 412
+G ++V++ D L Y VR F + + G R+ + QF FT+WPD GVP P L
Sbjct: 1464 HGLVQVTLLDTVELATYCVRTFALYKNGSSEKRE----VRQFQFTAWPDHGVPEHPTPFL 1519
Query: 413 KFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQR 472
FL++VK CNP AG +VVHCSAGVGRTG F+VIDAML+ + E+ VD+YG V+ +RAQR
Sbjct: 1520 AFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQR 1579
Query: 473 CQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLT 532
MVQT+ QY+FI+ ALLE G+TE+ +L ++QK+ G + G+E EFK+L
Sbjct: 1580 NYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLA 1639
Query: 533 SIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKD 592
S K + + NLP N KNR++ I+PYE RV + RG E +DY+NASFIDGYRQ+
Sbjct: 1640 SSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQK 1699
Query: 593 SYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVE 652
+YIA+QGPL T EDFWRM+WE S +VMLT+L E G+EKC QYWP++ Y V+
Sbjct: 1700 AYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVD 1759
Query: 653 LKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQ 712
E Y +R+ VT+ R+ +SR +RQF F WPE G+P G+G I I V K ++
Sbjct: 1760 PMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKE 1819
Query: 713 QSG-NHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ 771
Q G + PI+VHCSAG GRTG F LS VLER++ EG++D+FQTVK LR QRP MVQT +Q
Sbjct: 1820 QFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQ 1879
Query: 772 YEFCYKVVQEYIDAFSDYA 790
Y+F Y+ EY+ +F YA
Sbjct: 1880 YQFSYRAALEYLGSFDHYA 1898
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
precursor [Homo sapiens]
Length = 1903
Score = 601 bits (1550), Expect = e-172
Identities = 311/679 (45%), Positives = 428/679 (63%), Gaps = 18/679 (2%)
Query: 125 SSTAATTPETFP----PSDETPII----AVMVALSSLLVIVFIIIVLYMLRFKKYKQAGS 176
S AT+P + P D PI ++ + +L +VFII ++ + K K+A S
Sbjct: 1229 SKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRKRAES 1288
Query: 177 HSNSFRLSNGRT----EDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLF 232
S + N + +P + L +PP+P+ +L + I R A+DN F
Sbjct: 1289 DSRKSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKF 1348
Query: 233 REEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFI 292
+E+ ++ Q T E ++ E NK KNRY N++ YDHSRV L+ +EG+P SDY+NA++I
Sbjct: 1349 SQEYESIDPGQ-QFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYI 1407
Query: 293 NGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWT 352
+GY+++N +IA QG ET DFWRMIWEQ +AT+VM+T L+ER KC QYWP +G T
Sbjct: 1408 DGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTET 1467
Query: 353 YGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGML 412
+G ++V++ D L Y VR F + + G R+ + QF FT+WPD GVP P L
Sbjct: 1468 HGLVQVTLLDTVELATYCVRTFALYKNGSSEKRE----VRQFQFTAWPDHGVPEHPTPFL 1523
Query: 413 KFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQR 472
FL++VK CNP AG +VVHCSAGVGRTG F+VIDAML+ + E+ VD+YG V+ +RAQR
Sbjct: 1524 AFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQR 1583
Query: 473 CQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLT 532
MVQT+ QY+FI+ ALLE G+TE+ +L ++QK+ G + G+E EFK+L
Sbjct: 1584 NYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLA 1643
Query: 533 SIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKD 592
S K + + NLP N KNR++ I+PYE RV + RG E +DY+NASFIDGYRQ+
Sbjct: 1644 SSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQK 1703
Query: 593 SYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVE 652
+YIA+QGPL T EDFWRM+WE S +VMLT+L E G+EKC QYWP++ Y V+
Sbjct: 1704 AYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVD 1763
Query: 653 LKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQ 712
E Y +R+ VT+ R+ +SR +RQF F WPE G+P G+G I I V K ++
Sbjct: 1764 PMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKE 1823
Query: 713 QSG-NHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ 771
Q G + PI+VHCSAG GRTG F LS VLER++ EG++D+FQTVK LR QRP MVQT +Q
Sbjct: 1824 QFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQ 1883
Query: 772 YEFCYKVVQEYIDAFSDYA 790
Y+F Y+ EY+ +F YA
Sbjct: 1884 YQFSYRAALEYLGSFDHYA 1902
>gi|18860894 protein tyrosine phosphatase, receptor type, D isoform 4
precursor [Homo sapiens]
Length = 1501
Score = 601 bits (1550), Expect = e-172
Identities = 311/679 (45%), Positives = 428/679 (63%), Gaps = 18/679 (2%)
Query: 125 SSTAATTPETFP----PSDETPII----AVMVALSSLLVIVFIIIVLYMLRFKKYKQAGS 176
S AT+P + P D PI ++ + +L +VFII ++ + K K+A S
Sbjct: 827 SKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRKRAES 886
Query: 177 HSNSFRLSNGRT----EDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLF 232
S + N + +P + L +PP+P+ +L + I R A+DN F
Sbjct: 887 DSRKSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKF 946
Query: 233 REEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFI 292
+E+ ++ Q T E ++ E NK KNRY N++ YDHSRV L+ +EG+P SDY+NA++I
Sbjct: 947 SQEYESIDPGQ-QFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYI 1005
Query: 293 NGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWT 352
+GY+++N +IA QG ET DFWRMIWEQ +AT+VM+T L+ER KC QYWP +G T
Sbjct: 1006 DGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTET 1065
Query: 353 YGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGML 412
+G ++V++ D L Y VR F + + G R+ + QF FT+WPD GVP P L
Sbjct: 1066 HGLVQVTLLDTVELATYCVRTFALYKNGSSEKRE----VRQFQFTAWPDHGVPEHPTPFL 1121
Query: 413 KFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQR 472
FL++VK CNP AG +VVHCSAGVGRTG F+VIDAML+ + E+ VD+YG V+ +RAQR
Sbjct: 1122 AFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQR 1181
Query: 473 CQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLT 532
MVQT+ QY+FI+ ALLE G+TE+ +L ++QK+ G + G+E EFK+L
Sbjct: 1182 NYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLA 1241
Query: 533 SIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKD 592
S K + + NLP N KNR++ I+PYE RV + RG E +DY+NASFIDGYRQ+
Sbjct: 1242 SSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQK 1301
Query: 593 SYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVE 652
+YIA+QGPL T EDFWRM+WE S +VMLT+L E G+EKC QYWP++ Y V+
Sbjct: 1302 AYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVD 1361
Query: 653 LKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQ 712
E Y +R+ VT+ R+ +SR +RQF F WPE G+P G+G I I V K ++
Sbjct: 1362 PMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKE 1421
Query: 713 QSG-NHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ 771
Q G + PI+VHCSAG GRTG F LS VLER++ EG++D+FQTVK LR QRP MVQT +Q
Sbjct: 1422 QFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQ 1481
Query: 772 YEFCYKVVQEYIDAFSDYA 790
Y+F Y+ EY+ +F YA
Sbjct: 1482 YQFSYRAALEYLGSFDHYA 1500
>gi|104487002 protein tyrosine phosphatase, receptor type, D isoform 5
precursor [Homo sapiens]
Length = 1502
Score = 598 bits (1543), Expect = e-171
Identities = 307/678 (45%), Positives = 423/678 (62%), Gaps = 10/678 (1%)
Query: 118 TEPWEGNSSTAATTPETFPPSDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSH 177
T P+ + P+ +E I V L+ + +I +I +L K+A S
Sbjct: 829 TSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKSKPDRKRAESD 888
Query: 178 SNSFRLSNGRT----EDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFR 233
S + N + +P + L +PP+P+ +L + I R A+DN F
Sbjct: 889 SRKSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFS 948
Query: 234 EEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFIN 293
+E+ ++ Q T E ++ E NK KNRY N++ YDHSRV L+ +EG+P SDY+NA++I+
Sbjct: 949 QEYESIDPGQ-QFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYID 1007
Query: 294 GYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTY 353
GY+++N +IA QG ET DFWRMIWEQ +AT+VM+T L+ER KC QYWP +G T+
Sbjct: 1008 GYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETH 1067
Query: 354 GNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLK 413
G ++V++ D L Y VR F + + G R+ + QF FT+WPD GVP P L
Sbjct: 1068 GLVQVTLLDTVELATYCVRTFALYKNGSSEKRE----VRQFQFTAWPDHGVPEHPTPFLA 1123
Query: 414 FLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRC 473
FL++VK CNP AG +VVHCSAGVGRTG F+VIDAML+ + E+ VD+YG V+ +RAQR
Sbjct: 1124 FLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRN 1183
Query: 474 QMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTS 533
MVQT+ QY+FI+ ALLE G+TE+ +L ++QK+ G + G+E EFK+L S
Sbjct: 1184 YMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLAS 1243
Query: 534 IKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDS 593
K + + NLP N KNR++ I+PYE RV + RG E +DY+NASFIDGYRQ+ +
Sbjct: 1244 SKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKA 1303
Query: 594 YIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVEL 653
YIA+QGPL T EDFWRM+WE S +VMLT+L E G+EKC QYWP++ Y V+
Sbjct: 1304 YIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDP 1363
Query: 654 KKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQ 713
E Y +R+ VT+ R+ +SR +RQF F WPE G+P G+G I I V K ++Q
Sbjct: 1364 MAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQ 1423
Query: 714 SG-NHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQY 772
G + PI+VHCSAG GRTG F LS VLER++ EG++D+FQTVK LR QRP MVQT +QY
Sbjct: 1424 FGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQY 1483
Query: 773 EFCYKVVQEYIDAFSDYA 790
+F Y+ EY+ +F YA
Sbjct: 1484 QFSYRAALEYLGSFDHYA 1501
>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
isoform 4 precursor [Homo sapiens]
Length = 1505
Score = 589 bits (1518), Expect = e-168
Identities = 306/666 (45%), Positives = 420/666 (63%), Gaps = 20/666 (3%)
Query: 139 DETPII----AVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNS-----FRLSNGRTE 189
D PI+ ++ + +L +VFII ++ + K K +S L+N
Sbjct: 845 DPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPRTKCLLNNADLA 904
Query: 190 DVEPQSVPLLAR----SPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQ 245
P+ + R +P +PP+P+ + E R A+D+ +E+ ++ Q
Sbjct: 905 PHHPKDPVEMRRINFQTPGM-LSHPPIPIADMAEHTERLKANDSLKLSQEYESIDPGQ-Q 962
Query: 246 ATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQ 305
T E ++ E NK KNRY N++ YDHSRV L P+EG+ SDYINA++++GY+ +N +IA Q
Sbjct: 963 FTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQ 1022
Query: 306 GPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTV 365
GP ET DFWRM+WEQ +ATIVM+T L+E+ KC QYWP++G TYG I+V++ D
Sbjct: 1023 GPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIE 1082
Query: 366 LVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQY 425
L + VR F + + G R+ + QF FT+WPD GVP P L FL++VK CNP
Sbjct: 1083 LATFCVRTFSLHKNGSSEKRE----VRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPD 1138
Query: 426 AGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFI 485
AG IVVHCSAGVGRTG F+VIDAML+ + E+ VDVYG V+ +R+QR MVQT+ QY FI
Sbjct: 1139 AGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFI 1198
Query: 486 YQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGN 545
++ALLE G+TE+ SL ++QK+ PG G+E EFK+L + K + + N
Sbjct: 1199 HEALLEAVGCGNTEVPARSLYAYIQKLAQVEPGEHVTGMELEFKRLANSKAHTSRFISAN 1258
Query: 546 LPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTI 605
LP N KNR++ I+PYE RV + RG E +DY+NASFIDGYRQ+ +YIA+QGPL T
Sbjct: 1259 LPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETT 1318
Query: 606 EDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVR 665
EDFWRM+WE S +VMLT+L E G+EKC QYWP++ Y V+ E Y +R
Sbjct: 1319 EDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILR 1378
Query: 666 DLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSG-NHPITVHCS 724
+ VT+ R+ +SR +RQF F WPE G+P G+G I I V K ++Q G + PI+VHCS
Sbjct: 1379 EFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCS 1438
Query: 725 AGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID 784
AG GRTG F LS VLER++ EG++D+FQTVK LR QRP MVQT ++Y+FCY+ EY+
Sbjct: 1439 AGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLG 1498
Query: 785 AFSDYA 790
+F YA
Sbjct: 1499 SFDHYA 1504
>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
isoform 2 precursor [Homo sapiens]
Length = 1910
Score = 589 bits (1518), Expect = e-168
Identities = 306/666 (45%), Positives = 420/666 (63%), Gaps = 20/666 (3%)
Query: 139 DETPII----AVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNS-----FRLSNGRTE 189
D PI+ ++ + +L +VFII ++ + K K +S L+N
Sbjct: 1250 DPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPRTKCLLNNADLA 1309
Query: 190 DVEPQSVPLLAR----SPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQ 245
P+ + R +P +PP+P+ + E R A+D+ +E+ ++ Q
Sbjct: 1310 PHHPKDPVEMRRINFQTPGM-LSHPPIPIADMAEHTERLKANDSLKLSQEYESIDPGQ-Q 1367
Query: 246 ATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQ 305
T E ++ E NK KNRY N++ YDHSRV L P+EG+ SDYINA++++GY+ +N +IA Q
Sbjct: 1368 FTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQ 1427
Query: 306 GPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTV 365
GP ET DFWRM+WEQ +ATIVM+T L+E+ KC QYWP++G TYG I+V++ D
Sbjct: 1428 GPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIE 1487
Query: 366 LVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQY 425
L + VR F + + G R+ + QF FT+WPD GVP P L FL++VK CNP
Sbjct: 1488 LATFCVRTFSLHKNGSSEKRE----VRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPD 1543
Query: 426 AGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFI 485
AG IVVHCSAGVGRTG F+VIDAML+ + E+ VDVYG V+ +R+QR MVQT+ QY FI
Sbjct: 1544 AGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFI 1603
Query: 486 YQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGN 545
++ALLE G+TE+ SL ++QK+ PG G+E EFK+L + K + + N
Sbjct: 1604 HEALLEAVGCGNTEVPARSLYAYIQKLAQVEPGEHVTGMELEFKRLANSKAHTSRFISAN 1663
Query: 546 LPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTI 605
LP N KNR++ I+PYE RV + RG E +DY+NASFIDGYRQ+ +YIA+QGPL T
Sbjct: 1664 LPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETT 1723
Query: 606 EDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVR 665
EDFWRM+WE S +VMLT+L E G+EKC QYWP++ Y V+ E Y +R
Sbjct: 1724 EDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILR 1783
Query: 666 DLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSG-NHPITVHCS 724
+ VT+ R+ +SR +RQF F WPE G+P G+G I I V K ++Q G + PI+VHCS
Sbjct: 1784 EFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCS 1843
Query: 725 AGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID 784
AG GRTG F LS VLER++ EG++D+FQTVK LR QRP MVQT ++Y+FCY+ EY+
Sbjct: 1844 AGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLG 1903
Query: 785 AFSDYA 790
+F YA
Sbjct: 1904 SFDHYA 1909
>gi|104487295 protein tyrosine phosphatase, receptor type, sigma
isoform 3 precursor [Homo sapiens]
Length = 1501
Score = 589 bits (1518), Expect = e-168
Identities = 306/666 (45%), Positives = 420/666 (63%), Gaps = 20/666 (3%)
Query: 139 DETPII----AVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNS-----FRLSNGRTE 189
D PI+ ++ + +L +VFII ++ + K K +S L+N
Sbjct: 841 DPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPRTKCLLNNADLA 900
Query: 190 DVEPQSVPLLAR----SPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQ 245
P+ + R +P +PP+P+ + E R A+D+ +E+ ++ Q
Sbjct: 901 PHHPKDPVEMRRINFQTPGM-LSHPPIPIADMAEHTERLKANDSLKLSQEYESIDPGQ-Q 958
Query: 246 ATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQ 305
T E ++ E NK KNRY N++ YDHSRV L P+EG+ SDYINA++++GY+ +N +IA Q
Sbjct: 959 FTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQ 1018
Query: 306 GPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTV 365
GP ET DFWRM+WEQ +ATIVM+T L+E+ KC QYWP++G TYG I+V++ D
Sbjct: 1019 GPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIE 1078
Query: 366 LVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQY 425
L + VR F + + G R+ + QF FT+WPD GVP P L FL++VK CNP
Sbjct: 1079 LATFCVRTFSLHKNGSSEKRE----VRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPD 1134
Query: 426 AGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFI 485
AG IVVHCSAGVGRTG F+VIDAML+ + E+ VDVYG V+ +R+QR MVQT+ QY FI
Sbjct: 1135 AGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFI 1194
Query: 486 YQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGN 545
++ALLE G+TE+ SL ++QK+ PG G+E EFK+L + K + + N
Sbjct: 1195 HEALLEAVGCGNTEVPARSLYAYIQKLAQVEPGEHVTGMELEFKRLANSKAHTSRFISAN 1254
Query: 546 LPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTI 605
LP N KNR++ I+PYE RV + RG E +DY+NASFIDGYRQ+ +YIA+QGPL T
Sbjct: 1255 LPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETT 1314
Query: 606 EDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVR 665
EDFWRM+WE S +VMLT+L E G+EKC QYWP++ Y V+ E Y +R
Sbjct: 1315 EDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILR 1374
Query: 666 DLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSG-NHPITVHCS 724
+ VT+ R+ +SR +RQF F WPE G+P G+G I I V K ++Q G + PI+VHCS
Sbjct: 1375 EFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCS 1434
Query: 725 AGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID 784
AG GRTG F LS VLER++ EG++D+FQTVK LR QRP MVQT ++Y+FCY+ EY+
Sbjct: 1435 AGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLG 1494
Query: 785 AFSDYA 790
+F YA
Sbjct: 1495 SFDHYA 1500
>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
isoform 1 precursor [Homo sapiens]
Length = 1948
Score = 587 bits (1512), Expect = e-167
Identities = 290/583 (49%), Positives = 390/583 (66%), Gaps = 6/583 (1%)
Query: 209 YPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPY 268
+PP+P+ + E R A+D+ +E+ ++ Q T E ++ E NK KNRY N++ Y
Sbjct: 1370 HPPIPIADMAEHTERLKANDSLKLSQEYESIDPGQ-QFTWEHSNLEVNKPKNRYANVIAY 1428
Query: 269 DHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIV 328
DHSRV L P+EG+ SDYINA++++GY+ +N +IA QGP ET DFWRM+WEQ +ATIV
Sbjct: 1429 DHSRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIV 1488
Query: 329 MVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQ 388
M+T L+E+ KC QYWP++G TYG I+V++ D L + VR F + + G R+
Sbjct: 1489 MMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKRE-- 1546
Query: 389 RLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDA 448
+ QF FT+WPD GVP P L FL++VK CNP AG IVVHCSAGVGRTG F+VIDA
Sbjct: 1547 --VRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDA 1604
Query: 449 MLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETH 508
ML+ + E+ VDVYG V+ +R+QR MVQT+ QY FI++ALLE G+TE+ SL +
Sbjct: 1605 MLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAY 1664
Query: 509 LQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVII 568
+QK+ PG G+E EFK+L + K + + NLP N KNR++ I+PYE RV +
Sbjct: 1665 IQKLAQVEPGEHVTGMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCL 1724
Query: 569 PVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEE 628
RG E +DY+NASFIDGYRQ+ +YIA+QGPL T EDFWRM+WE S +VMLT+L E
Sbjct: 1725 QPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLRE 1784
Query: 629 RGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGW 688
G+EKC QYWP++ Y V+ E Y +R+ VT+ R+ +SR +RQF F W
Sbjct: 1785 MGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDW 1844
Query: 689 PEVGIPSDGKGMISIIAAVQKQQQQSG-NHPITVHCSAGAGRTGTFCALSTVLERVKAEG 747
PE G+P G+G I I V K ++Q G + PI+VHCSAG GRTG F LS VLER++ EG
Sbjct: 1845 PEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEG 1904
Query: 748 ILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYA 790
++D+FQTVK LR QRP MVQT ++Y+FCY+ EY+ +F YA
Sbjct: 1905 VVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYA 1947
>gi|18641364 protein tyrosine phosphatase, receptor type, C isoform 3
precursor [Homo sapiens]
Length = 1256
Score = 471 bits (1212), Expect = e-132
Identities = 267/668 (39%), Positives = 391/668 (58%), Gaps = 56/668 (8%)
Query: 147 MVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTN 206
++A + L+IV I +L +L YK H + + E VE L
Sbjct: 529 LIAFLAFLIIVTSIALLVVL----YKIYDLHKKRSCNLDEQQELVERDDEKQLMN----- 579
Query: 207 RKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNIL 266
P+ D L E R++AD+ +LF EF ++P + + A K N+ KNRYV+IL
Sbjct: 580 --VEPIHADILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDIL 637
Query: 267 PYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTAT 326
PYD++RV L+ + G S+YINAS+I+G++E K+IAAQGP++ETV+DFWRMIWEQ
Sbjct: 638 PYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATV 697
Query: 327 IVMVTNLKERKECKCAQYWP--DQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTN 384
IVMVT +E KCA+YWP ++G +G++ V + DY ++K ++ N
Sbjct: 698 IVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKL------NIVN 751
Query: 385 RKPQ---RLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTG 441
+K + R +T FTSWPD GVP P +LK ++V A + ++G IVVHCSAGVGRTG
Sbjct: 752 KKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTG 811
Query: 442 TFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELE 501
T++ IDAML+ + E KVDVYG+V ++R QRC MVQ + QY+ I+QAL+E+ +G+TE+
Sbjct: 812 TYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVN 871
Query: 502 VTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPY 561
++ L +L + + P + + LE EF++L S + + GN N KNR +IPY
Sbjct: 872 LSELHPYLHNMKKRDPPSEPSPLEAEFQRLPSYRSWRTQ-HIGNQEENKSKNRNSNVIPY 930
Query: 562 EFNRVIIPVKR---------------------GEENTDYVNASFIDGYRQKDSYIASQGP 600
++NRV P+K EE + Y+NASFI Y + + IA+QGP
Sbjct: 931 DYNRV--PLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYWKPEVMIAAQGP 988
Query: 601 LLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECE 660
L TI DFW+MI++ K IVMLTEL+ QE CAQYW +G +YGDI V+LK ++
Sbjct: 989 LKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYW-GEGKQTYGDIEVDLKDTDKSS 1047
Query: 661 SYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAV-----QKQQQQSG 715
+YT+R + +++ SR + Q+ + W +P++ K +IS+I V QK +
Sbjct: 1048 TYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGN 1107
Query: 716 NH----PITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ 771
H P+ +HC G+ +TG FCAL +LE + E ++D+FQ VK+LR RP MV T EQ
Sbjct: 1108 KHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQ 1167
Query: 772 YEFCYKVV 779
Y+F Y V+
Sbjct: 1168 YQFLYDVI 1175
Score = 197 bits (501), Expect = 3e-50
Identities = 96/239 (40%), Positives = 146/239 (61%), Gaps = 4/239 (1%)
Query: 547 PANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIE 606
P N KNR + I+PY++NRV + G+ ++Y+NAS+IDG+++ YIA+QGP T++
Sbjct: 625 PFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVD 684
Query: 607 DFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPS--DGLVSYGDITVELKKEEECESYTV 664
DFWRMIWE K+ IVM+T EE + KCA+YWPS +G ++GD+ V++ + + C Y +
Sbjct: 685 DFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYII 744
Query: 665 RDLLVTNTRENKS-RQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHC 723
+ L + N +E + R++ F WP+ G+P D ++ + V PI VHC
Sbjct: 745 QKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSG-PIVVHC 803
Query: 724 SAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEY 782
SAG GRTGT+ + +LE ++AE +DV+ V LR QR MVQ QY ++ + EY
Sbjct: 804 SAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY 862
Score = 160 bits (404), Expect = 6e-39
Identities = 100/288 (34%), Positives = 146/288 (50%), Gaps = 34/288 (11%)
Query: 235 EFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLT-----PVEGVPDSD---- 285
EF LP+ T ++EENK KNR N++PYD++RV L E DSD
Sbjct: 897 EFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSD 956
Query: 286 ----------YINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKE 335
YINASFI Y + IAAQGP +ET+ DFW+MI+++ IVM+T LK
Sbjct: 957 DDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKH 1016
Query: 336 RKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFH 395
+ CAQYW +G TYG+I V ++D YT+R F ++ + RK R + Q+
Sbjct: 1017 GDQEICAQYW-GEGKQTYGDIEVDLKDTDKSSTYTLRVFELRH----SKRKDSRTVYQYQ 1071
Query: 396 FTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGA----------IVVHCSAGVGRTGTFVV 445
+T+W +P P ++ ++ VK PQ + +++HC G +TG F
Sbjct: 1072 YTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCA 1131
Query: 446 IDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHY 493
+ +L+ TE VD++ V +R R MV T QY F+Y + Y
Sbjct: 1132 LLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTY 1179
>gi|18641347 protein tyrosine phosphatase, receptor type, C isoform 1
precursor [Homo sapiens]
Length = 1304
Score = 471 bits (1212), Expect = e-132
Identities = 267/668 (39%), Positives = 391/668 (58%), Gaps = 56/668 (8%)
Query: 147 MVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTN 206
++A + L+IV I +L +L YK H + + E VE L
Sbjct: 577 LIAFLAFLIIVTSIALLVVL----YKIYDLHKKRSCNLDEQQELVERDDEKQLMN----- 627
Query: 207 RKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNIL 266
P+ D L E R++AD+ +LF EF ++P + + A K N+ KNRYV+IL
Sbjct: 628 --VEPIHADILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDIL 685
Query: 267 PYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTAT 326
PYD++RV L+ + G S+YINAS+I+G++E K+IAAQGP++ETV+DFWRMIWEQ
Sbjct: 686 PYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATV 745
Query: 327 IVMVTNLKERKECKCAQYWP--DQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTN 384
IVMVT +E KCA+YWP ++G +G++ V + DY ++K ++ N
Sbjct: 746 IVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKL------NIVN 799
Query: 385 RKPQ---RLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTG 441
+K + R +T FTSWPD GVP P +LK ++V A + ++G IVVHCSAGVGRTG
Sbjct: 800 KKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTG 859
Query: 442 TFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELE 501
T++ IDAML+ + E KVDVYG+V ++R QRC MVQ + QY+ I+QAL+E+ +G+TE+
Sbjct: 860 TYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVN 919
Query: 502 VTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPY 561
++ L +L + + P + + LE EF++L S + + GN N KNR +IPY
Sbjct: 920 LSELHPYLHNMKKRDPPSEPSPLEAEFQRLPSYRSWRTQ-HIGNQEENKSKNRNSNVIPY 978
Query: 562 EFNRVIIPVKR---------------------GEENTDYVNASFIDGYRQKDSYIASQGP 600
++NRV P+K EE + Y+NASFI Y + + IA+QGP
Sbjct: 979 DYNRV--PLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYWKPEVMIAAQGP 1036
Query: 601 LLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECE 660
L TI DFW+MI++ K IVMLTEL+ QE CAQYW +G +YGDI V+LK ++
Sbjct: 1037 LKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYW-GEGKQTYGDIEVDLKDTDKSS 1095
Query: 661 SYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAV-----QKQQQQSG 715
+YT+R + +++ SR + Q+ + W +P++ K +IS+I V QK +
Sbjct: 1096 TYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGN 1155
Query: 716 NH----PITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ 771
H P+ +HC G+ +TG FCAL +LE + E ++D+FQ VK+LR RP MV T EQ
Sbjct: 1156 KHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQ 1215
Query: 772 YEFCYKVV 779
Y+F Y V+
Sbjct: 1216 YQFLYDVI 1223
Score = 197 bits (501), Expect = 3e-50
Identities = 96/239 (40%), Positives = 146/239 (61%), Gaps = 4/239 (1%)
Query: 547 PANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIE 606
P N KNR + I+PY++NRV + G+ ++Y+NAS+IDG+++ YIA+QGP T++
Sbjct: 673 PFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVD 732
Query: 607 DFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPS--DGLVSYGDITVELKKEEECESYTV 664
DFWRMIWE K+ IVM+T EE + KCA+YWPS +G ++GD+ V++ + + C Y +
Sbjct: 733 DFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYII 792
Query: 665 RDLLVTNTRENKS-RQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHC 723
+ L + N +E + R++ F WP+ G+P D ++ + V PI VHC
Sbjct: 793 QKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSG-PIVVHC 851
Query: 724 SAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEY 782
SAG GRTGT+ + +LE ++AE +DV+ V LR QR MVQ QY ++ + EY
Sbjct: 852 SAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY 910
Score = 160 bits (404), Expect = 6e-39
Identities = 100/288 (34%), Positives = 146/288 (50%), Gaps = 34/288 (11%)
Query: 235 EFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLT-----PVEGVPDSD---- 285
EF LP+ T ++EENK KNR N++PYD++RV L E DSD
Sbjct: 945 EFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSD 1004
Query: 286 ----------YINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKE 335
YINASFI Y + IAAQGP +ET+ DFW+MI+++ IVM+T LK
Sbjct: 1005 DDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKH 1064
Query: 336 RKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFH 395
+ CAQYW +G TYG+I V ++D YT+R F ++ + RK R + Q+
Sbjct: 1065 GDQEICAQYW-GEGKQTYGDIEVDLKDTDKSSTYTLRVFELRH----SKRKDSRTVYQYQ 1119
Query: 396 FTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGA----------IVVHCSAGVGRTGTFVV 445
+T+W +P P ++ ++ VK PQ + +++HC G +TG F
Sbjct: 1120 YTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCA 1179
Query: 446 IDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHY 493
+ +L+ TE VD++ V +R R MV T QY F+Y + Y
Sbjct: 1180 LLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTY 1227
>gi|18641362 protein tyrosine phosphatase, receptor type, C isoform 2
precursor [Homo sapiens]
Length = 1143
Score = 471 bits (1212), Expect = e-132
Identities = 267/668 (39%), Positives = 391/668 (58%), Gaps = 56/668 (8%)
Query: 147 MVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTN 206
++A + L+IV I +L +L YK H + + E VE L
Sbjct: 416 LIAFLAFLIIVTSIALLVVL----YKIYDLHKKRSCNLDEQQELVERDDEKQLMN----- 466
Query: 207 RKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNIL 266
P+ D L E R++AD+ +LF EF ++P + + A K N+ KNRYV+IL
Sbjct: 467 --VEPIHADILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDIL 524
Query: 267 PYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTAT 326
PYD++RV L+ + G S+YINAS+I+G++E K+IAAQGP++ETV+DFWRMIWEQ
Sbjct: 525 PYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATV 584
Query: 327 IVMVTNLKERKECKCAQYWP--DQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTN 384
IVMVT +E KCA+YWP ++G +G++ V + DY ++K ++ N
Sbjct: 585 IVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKL------NIVN 638
Query: 385 RKPQ---RLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTG 441
+K + R +T FTSWPD GVP P +LK ++V A + ++G IVVHCSAGVGRTG
Sbjct: 639 KKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTG 698
Query: 442 TFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELE 501
T++ IDAML+ + E KVDVYG+V ++R QRC MVQ + QY+ I+QAL+E+ +G+TE+
Sbjct: 699 TYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVN 758
Query: 502 VTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPY 561
++ L +L + + P + + LE EF++L S + + GN N KNR +IPY
Sbjct: 759 LSELHPYLHNMKKRDPPSEPSPLEAEFQRLPSYRSWRTQ-HIGNQEENKSKNRNSNVIPY 817
Query: 562 EFNRVIIPVKR---------------------GEENTDYVNASFIDGYRQKDSYIASQGP 600
++NRV P+K EE + Y+NASFI Y + + IA+QGP
Sbjct: 818 DYNRV--PLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYWKPEVMIAAQGP 875
Query: 601 LLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECE 660
L TI DFW+MI++ K IVMLTEL+ QE CAQYW +G +YGDI V+LK ++
Sbjct: 876 LKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYW-GEGKQTYGDIEVDLKDTDKSS 934
Query: 661 SYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAV-----QKQQQQSG 715
+YT+R + +++ SR + Q+ + W +P++ K +IS+I V QK +
Sbjct: 935 TYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGN 994
Query: 716 NH----PITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ 771
H P+ +HC G+ +TG FCAL +LE + E ++D+FQ VK+LR RP MV T EQ
Sbjct: 995 KHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQ 1054
Query: 772 YEFCYKVV 779
Y+F Y V+
Sbjct: 1055 YQFLYDVI 1062
Score = 197 bits (501), Expect = 3e-50
Identities = 96/239 (40%), Positives = 146/239 (61%), Gaps = 4/239 (1%)
Query: 547 PANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIE 606
P N KNR + I+PY++NRV + G+ ++Y+NAS+IDG+++ YIA+QGP T++
Sbjct: 512 PFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVD 571
Query: 607 DFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPS--DGLVSYGDITVELKKEEECESYTV 664
DFWRMIWE K+ IVM+T EE + KCA+YWPS +G ++GD+ V++ + + C Y +
Sbjct: 572 DFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYII 631
Query: 665 RDLLVTNTRENKS-RQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHC 723
+ L + N +E + R++ F WP+ G+P D ++ + V PI VHC
Sbjct: 632 QKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSG-PIVVHC 690
Query: 724 SAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEY 782
SAG GRTGT+ + +LE ++AE +DV+ V LR QR MVQ QY ++ + EY
Sbjct: 691 SAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY 749
Score = 160 bits (404), Expect = 6e-39
Identities = 100/288 (34%), Positives = 146/288 (50%), Gaps = 34/288 (11%)
Query: 235 EFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLT-----PVEGVPDSD---- 285
EF LP+ T ++EENK KNR N++PYD++RV L E DSD
Sbjct: 784 EFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSD 843
Query: 286 ----------YINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKE 335
YINASFI Y + IAAQGP +ET+ DFW+MI+++ IVM+T LK
Sbjct: 844 DDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKH 903
Query: 336 RKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFH 395
+ CAQYW +G TYG+I V ++D YT+R F ++ + RK R + Q+
Sbjct: 904 GDQEICAQYW-GEGKQTYGDIEVDLKDTDKSSTYTLRVFELRH----SKRKDSRTVYQYQ 958
Query: 396 FTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGA----------IVVHCSAGVGRTGTFVV 445
+T+W +P P ++ ++ VK PQ + +++HC G +TG F
Sbjct: 959 YTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCA 1018
Query: 446 IDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHY 493
+ +L+ TE VD++ V +R R MV T QY F+Y + Y
Sbjct: 1019 LLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTY 1066
>gi|18860902 protein tyrosine phosphatase, receptor type, K isoform b
[Homo sapiens]
Length = 1440
Score = 441 bits (1135), Expect = e-123
Identities = 236/588 (40%), Positives = 356/588 (60%), Gaps = 16/588 (2%)
Query: 205 TNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVN 264
T + +P + V L + IN D+ F+EE+ + A+ + A K++N+ KNRY N
Sbjct: 861 TGQLHPAIRVADLLQHINLMKTSDSYGFKEEYESFFEGQ-SASWDVAKKDQNRAKNRYGN 919
Query: 265 ILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNT 324
I+ YDHSRV L PVE P SDYINA++I+GYQ + +IA QGP ETV DFWRMIW++ +
Sbjct: 920 IIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETVYDFWRMIWQEQS 979
Query: 325 ATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTN 384
A IVMVTNL E KC +YWPD YG+ +V+ ++ L +Y VR F +++ G
Sbjct: 980 ACIVMVTNLVEVGRVKCYKYWPDD-TEVYGDFKVTCVEMEPLAEYVVRTFTLERRGYNEI 1038
Query: 385 RKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFV 444
R+ + QFHFT WPD GVP+ G+L F+++VK NP AG IVVHCSAG GRTG ++
Sbjct: 1039 RE----VKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPSAGPIVVHCSAGAGRTGCYI 1094
Query: 445 VIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTS 504
VID MLDM E VD+Y V +R++R MVQT+ QY+FI+ A+LE L G+T + V
Sbjct: 1095 VIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACLCGETAIPVCE 1154
Query: 505 LETHLQKIYNKIPGTSNNGLEEEFKKLTSI--KIQNDKMRTGNLPANMKKNRVLQIIPYE 562
+ + T+++ L++EF+ L S+ ++Q + LP N KNR + ++P +
Sbjct: 1155 FKAAYFDMIRIDSQTNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPD 1214
Query: 563 FNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVM 622
+ G E+++Y+NA+ +D YRQ ++I +Q PL +T++DFWR+++++ SIVM
Sbjct: 1215 RCLPFLITIDG-ESSNYINAALMDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVM 1273
Query: 623 LTELEERGQEKCAQYWPSDGLVSYGDITVE-LKKEEECESYTVRDLLVTNTRENKS-RQI 680
L E++ + C QYWP +G++ YG I VE + +C+ + TR + +
Sbjct: 1274 LNEVDL--SQGCPQYWPEEGMLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLMV 1331
Query: 681 RQFHFHGW-PEVGIPSDGKGMISIIAAVQKQQQ--QSGNHPITVHCSAGAGRTGTFCALS 737
+QF + GW +P + + +I V+K Q+ + G +HC G GR+G FCA+
Sbjct: 1332 QQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIG 1391
Query: 738 TVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDA 785
V+E VK + ++DVF VK+LR +P+MV+ EQY FCY V EY+++
Sbjct: 1392 IVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLES 1439
>gi|157419150 protein tyrosine phosphatase, receptor type, M isoform 2
precursor [Homo sapiens]
Length = 1452
Score = 440 bits (1131), Expect = e-123
Identities = 235/601 (39%), Positives = 361/601 (60%), Gaps = 21/601 (3%)
Query: 192 EPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAA 251
EP VP T + +P + V L + I + + F+EE+ + A ++A
Sbjct: 865 EPADVPY-----QTGQLHPAIRVADLLQHITQMKCAEGYGFKEEYESFFEGQ-SAPWDSA 918
Query: 252 SKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEET 311
K+EN+ KNRY NI+ YDHSRV L +EG +SDYIN ++I+GY N +IA QGP +ET
Sbjct: 919 KKDENRMKNRYGNIIAYDHSRVRLQTIEGDTNSDYINGNYIDGYHRPNHYIATQGPMQET 978
Query: 312 VNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTV 371
+ DFWRM+W +NTA+I+MVTNL E KC +YWPD Y +I+V++ + +L +Y +
Sbjct: 979 IYDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWPDD-TEIYKDIKVTLIETELLAEYVI 1037
Query: 372 RKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVV 431
R F +++ G R+ I QFHFT WPD GVP+ G+L F+++VK+ +P AG +VV
Sbjct: 1038 RTFAVEKRGVHEIRE----IRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPSAGPLVV 1093
Query: 432 HCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE 491
HCSAG GRTG F+VID MLDM E VD+Y V +R++R MVQT+ QYVFI+ A+LE
Sbjct: 1094 HCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILE 1153
Query: 492 HYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSI--KIQNDKMRTGNLPAN 549
L GDT + + + + + P T+++ ++EEF+ L + ++ + LP N
Sbjct: 1154 ACLCGDTSVPASQVRSLYYDMNKLDPQTNSSQIKEEFRTLNMVTPTLRVEDCSIALLPRN 1213
Query: 550 MKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFW 609
+KNR + I+P + + G E+++Y+NA+ +D Y+Q ++I +Q PL +T++DFW
Sbjct: 1214 HEKNRCMDILPPDRCLPFLITIDG-ESSNYINAALMDSYKQPSAFIVTQHPLPNTVKDFW 1272
Query: 610 RMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLV 669
R++ ++ S+VML +++ + C QYWP +G+ +G I VE + E R +
Sbjct: 1273 RLVLDYHCTSVVMLNDVDP--AQLCPQYWPENGVHRHGPIQVEFVSADLEEDIISRIFRI 1330
Query: 670 TNTR--ENKSRQIRQFHFHGWPEV-GIPSDGKGMISIIAAVQKQQQQ--SGNHPITVHCS 724
N ++ R ++QF F GWP P + + +I V K Q++ G VHC
Sbjct: 1331 YNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRTVVHCL 1390
Query: 725 AGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID 784
G GR+GTFCA+S V E ++ + +DVF VK+LR +P+MV L+QY+FCY+V EY++
Sbjct: 1391 NGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLN 1450
Query: 785 A 785
+
Sbjct: 1451 S 1451
>gi|157419152 protein tyrosine phosphatase, receptor type, M isoform 1
precursor [Homo sapiens]
Length = 1465
Score = 440 bits (1131), Expect = e-123
Identities = 235/601 (39%), Positives = 361/601 (60%), Gaps = 21/601 (3%)
Query: 192 EPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAA 251
EP VP T + +P + V L + I + + F+EE+ + A ++A
Sbjct: 878 EPADVPY-----QTGQLHPAIRVADLLQHITQMKCAEGYGFKEEYESFFEGQ-SAPWDSA 931
Query: 252 SKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEET 311
K+EN+ KNRY NI+ YDHSRV L +EG +SDYIN ++I+GY N +IA QGP +ET
Sbjct: 932 KKDENRMKNRYGNIIAYDHSRVRLQTIEGDTNSDYINGNYIDGYHRPNHYIATQGPMQET 991
Query: 312 VNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTV 371
+ DFWRM+W +NTA+I+MVTNL E KC +YWPD Y +I+V++ + +L +Y +
Sbjct: 992 IYDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWPDD-TEIYKDIKVTLIETELLAEYVI 1050
Query: 372 RKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVV 431
R F +++ G R+ I QFHFT WPD GVP+ G+L F+++VK+ +P AG +VV
Sbjct: 1051 RTFAVEKRGVHEIRE----IRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPSAGPLVV 1106
Query: 432 HCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE 491
HCSAG GRTG F+VID MLDM E VD+Y V +R++R MVQT+ QYVFI+ A+LE
Sbjct: 1107 HCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILE 1166
Query: 492 HYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSI--KIQNDKMRTGNLPAN 549
L GDT + + + + + P T+++ ++EEF+ L + ++ + LP N
Sbjct: 1167 ACLCGDTSVPASQVRSLYYDMNKLDPQTNSSQIKEEFRTLNMVTPTLRVEDCSIALLPRN 1226
Query: 550 MKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFW 609
+KNR + I+P + + G E+++Y+NA+ +D Y+Q ++I +Q PL +T++DFW
Sbjct: 1227 HEKNRCMDILPPDRCLPFLITIDG-ESSNYINAALMDSYKQPSAFIVTQHPLPNTVKDFW 1285
Query: 610 RMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLV 669
R++ ++ S+VML +++ + C QYWP +G+ +G I VE + E R +
Sbjct: 1286 RLVLDYHCTSVVMLNDVDP--AQLCPQYWPENGVHRHGPIQVEFVSADLEEDIISRIFRI 1343
Query: 670 TNTR--ENKSRQIRQFHFHGWPEV-GIPSDGKGMISIIAAVQKQQQQ--SGNHPITVHCS 724
N ++ R ++QF F GWP P + + +I V K Q++ G VHC
Sbjct: 1344 YNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRTVVHCL 1403
Query: 725 AGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID 784
G GR+GTFCA+S V E ++ + +DVF VK+LR +P+MV L+QY+FCY+V EY++
Sbjct: 1404 NGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLN 1463
Query: 785 A 785
+
Sbjct: 1464 S 1464
>gi|208431815 protein tyrosine phosphatase, receptor type, K isoform a
[Homo sapiens]
Length = 1446
Score = 435 bits (1118), Expect = e-122
Identities = 236/594 (39%), Positives = 356/594 (59%), Gaps = 22/594 (3%)
Query: 205 TNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVN 264
T + +P + V L + IN D+ F+EE+ + A+ + A K++N+ KNRY N
Sbjct: 861 TGQLHPAIRVADLLQHINLMKTSDSYGFKEEYESFFEGQ-SASWDVAKKDQNRAKNRYGN 919
Query: 265 ILPYDHSRVHLTPVEGVPDSDYINASFIN------GYQEKNKFIAAQGPKEETVNDFWRM 318
I+ YDHSRV L PVE P SDYINA++I+ GYQ + +IA QGP ETV DFWRM
Sbjct: 920 IIAYDHSRVILQPVEDDPSSDYINANYIDIWLYRDGYQRPSHYIATQGPVHETVYDFWRM 979
Query: 319 IWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQ 378
IW++ +A IVMVTNL E KC +YWPD YG+ +V+ ++ L +Y VR F +++
Sbjct: 980 IWQEQSACIVMVTNLVEVGRVKCYKYWPDD-TEVYGDFKVTCVEMEPLAEYVVRTFTLER 1038
Query: 379 VGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVG 438
G R+ + QFHFT WPD GVP+ G+L F+++VK NP AG IVVHCSAG G
Sbjct: 1039 RGYNEIRE----VKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPSAGPIVVHCSAGAG 1094
Query: 439 RTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDT 498
RTG ++VID MLDM E VD+Y V +R++R MVQT+ QY+FI+ A+LE L G+T
Sbjct: 1095 RTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACLCGET 1154
Query: 499 ELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSI--KIQNDKMRTGNLPANMKKNRVL 556
+ V + + T+++ L++EF+ L S+ ++Q + LP N KNR +
Sbjct: 1155 AIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRNHDKNRFM 1214
Query: 557 QIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWK 616
++P + + G E+++Y+NA+ +D YRQ ++I +Q PL +T++DFWR+++++
Sbjct: 1215 DMLPPDRCLPFLITIDG-ESSNYINAALMDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYG 1273
Query: 617 SCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVE-LKKEEECESYTVRDLLVTNTREN 675
SIVML E++ + C QYWP +G++ YG I VE + +C+ + TR
Sbjct: 1274 CTSIVMLNEVDL--SQGCPQYWPEEGMLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQ 1331
Query: 676 KS-RQIRQFHFHGW-PEVGIPSDGKGMISIIAAVQKQQQ--QSGNHPITVHCSAGAGRTG 731
+ ++QF + GW +P + + +I V+K Q+ + G +HC G GR+G
Sbjct: 1332 EGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSG 1391
Query: 732 TFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDA 785
FCA+ V+E VK + ++DVF VK+LR +P+MV+ EQY FCY V EY+++
Sbjct: 1392 MFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLES 1445
>gi|148539860 protein tyrosine phosphatase, receptor type, T isoform 2
precursor [Homo sapiens]
Length = 1441
Score = 434 bits (1117), Expect = e-121
Identities = 231/584 (39%), Positives = 352/584 (60%), Gaps = 16/584 (2%)
Query: 210 PPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYD 269
P + V L + I + F+EE+ ALP A+ + A ++EN+ KNRY NI+ YD
Sbjct: 867 PAIRVADLLQHITQMKRGQGYGFKEEYEALPEGQT-ASWDTAKEDENRNKNRYGNIISYD 925
Query: 270 HSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVM 329
HSRV L ++G P SDYINA++I+GY +IA QGP +ETV DFWRMIW++N+A+IVM
Sbjct: 926 HSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVM 985
Query: 330 VTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQR 389
VTNL E KC +YWPD YG+I+V++ + L +Y +R F +Q+ G R+
Sbjct: 986 VTNLVEVGRVKCVRYWPDD-TEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRE--- 1041
Query: 390 LITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAM 449
+ FHFTSWPD GVP G+L F+++VK NP AG IVVHCSAG GRTG F+ ID M
Sbjct: 1042 -LRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTM 1100
Query: 450 LDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHL 509
LDM E VD++ V +RAQR +VQT+ QYVF++ A+LE L G+T + V +
Sbjct: 1101 LDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLY 1160
Query: 510 QKIYNKIPGTSNNGLEEEFKKLTSI--KIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVI 567
I P T+++ +++EF+ L + +++ + G LP N KNR + ++P + +
Sbjct: 1161 YNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLD-RCLP 1219
Query: 568 IPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELE 627
+ E+++Y+NA+ +D ++Q +++ +Q PL +T+ DFWR+++++ S+VML E++
Sbjct: 1220 FLISVDGESSNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMD 1279
Query: 628 ERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTR--ENKSRQIRQFHF 685
+ C QYWP YG I VE + E R + N ++ R ++ +
Sbjct: 1280 T--AQFCMQYWPEKTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQY 1337
Query: 686 HGWPEV-GIPSDGKGMISIIAAVQK-QQQQSGNHPIT-VHCSAGAGRTGTFCALSTVLER 742
GWP P + ++ ++ ++K Q+Q G T VHC G GR+GTFCA+ +V E
Sbjct: 1338 IGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEM 1397
Query: 743 VKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAF 786
++ + I+DVF VK+LR + +MV+TLEQY+F Y+V EY+ +F
Sbjct: 1398 IQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF 1441
>gi|148539858 protein tyrosine phosphatase, receptor type, T isoform 1
precursor [Homo sapiens]
Length = 1460
Score = 434 bits (1117), Expect = e-121
Identities = 231/584 (39%), Positives = 352/584 (60%), Gaps = 16/584 (2%)
Query: 210 PPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYD 269
P + V L + I + F+EE+ ALP A+ + A ++EN+ KNRY NI+ YD
Sbjct: 886 PAIRVADLLQHITQMKRGQGYGFKEEYEALPEGQT-ASWDTAKEDENRNKNRYGNIISYD 944
Query: 270 HSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVM 329
HSRV L ++G P SDYINA++I+GY +IA QGP +ETV DFWRMIW++N+A+IVM
Sbjct: 945 HSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVM 1004
Query: 330 VTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQR 389
VTNL E KC +YWPD YG+I+V++ + L +Y +R F +Q+ G R+
Sbjct: 1005 VTNLVEVGRVKCVRYWPDD-TEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRE--- 1060
Query: 390 LITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAM 449
+ FHFTSWPD GVP G+L F+++VK NP AG IVVHCSAG GRTG F+ ID M
Sbjct: 1061 -LRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTM 1119
Query: 450 LDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHL 509
LDM E VD++ V +RAQR +VQT+ QYVF++ A+LE L G+T + V +
Sbjct: 1120 LDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLY 1179
Query: 510 QKIYNKIPGTSNNGLEEEFKKLTSI--KIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVI 567
I P T+++ +++EF+ L + +++ + G LP N KNR + ++P + +
Sbjct: 1180 YNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLD-RCLP 1238
Query: 568 IPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELE 627
+ E+++Y+NA+ +D ++Q +++ +Q PL +T+ DFWR+++++ S+VML E++
Sbjct: 1239 FLISVDGESSNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMD 1298
Query: 628 ERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTR--ENKSRQIRQFHF 685
+ C QYWP YG I VE + E R + N ++ R ++ +
Sbjct: 1299 T--AQFCMQYWPEKTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQY 1356
Query: 686 HGWPEV-GIPSDGKGMISIIAAVQK-QQQQSGNHPIT-VHCSAGAGRTGTFCALSTVLER 742
GWP P + ++ ++ ++K Q+Q G T VHC G GR+GTFCA+ +V E
Sbjct: 1357 IGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEM 1416
Query: 743 VKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAF 786
++ + I+DVF VK+LR + +MV+TLEQY+F Y+V EY+ +F
Sbjct: 1417 IQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF 1460
>gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1
precursor [Homo sapiens]
Length = 2315
Score = 408 bits (1048), Expect = e-113
Identities = 256/761 (33%), Positives = 399/761 (52%), Gaps = 36/761 (4%)
Query: 42 PVKEEAKT----SNPTSSLTSLSVAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSI 97
P+ E+K ++ S + + + + N T N D+D S +
Sbjct: 1532 PLSPESKAWAVLTSDEESGSGQGTSDSLNENETSTDFSFADTNEKDADGILAAGDSEITP 1591
Query: 98 GITISPNGTWLPDNQFTDARTEPWEGNSSTAATTPETFPPSDETPIIAVMVALSSLLVIV 157
G SP + +N +E NSS + E + +V +S+L I
Sbjct: 1592 GFPQSPTSSVTSENSEVFHVSEAEASNSSHESRIGLAEGLESEKKAVIPLVIVSALTFIC 1651
Query: 158 FIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSV-PLLARSPSTNRKYPPLPVDK 216
+++V ++ ++K Q +H ++ R P + P+ + K+ P V
Sbjct: 1652 LVVLVGILIYWRKCFQT-AHFYLEDSTSPRVISTPPTPIFPISDDVGAIPIKHFPKHVAD 1710
Query: 217 LEEEINRRMADDNKLFREEFNALPACPIQA--TCEAASKEENKEKNRYVNILPYDHSRVH 274
L ++ + +E + + +C + T ++++ +NK KNRY+NI+ YDHSRV
Sbjct: 1711 LHASSG--FTEEFETLKEFYQEVQSCTVDLGITADSSNHPDNKHKNRYINIVAYDHSRVK 1768
Query: 275 LTPVEGVPD--SDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTN 332
L + +DYINA++++GY +IAAQGP + T DFWRMIWE N IVM+TN
Sbjct: 1769 LAQLAEKDGKLTDYINANYVDGYNRPKAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITN 1828
Query: 333 LKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQV----GDMTNRKPQ 388
L E+ KC QYWP G YGN V+ + V VL YTVR F ++ G R
Sbjct: 1829 LVEKGRRKCDQYWPADGSEEYGNFLVTQKSVQVLAYYTVRNFTLRNTKIKKGSQKGRPSG 1888
Query: 389 RLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDA 448
R++TQ+H+T WPD GVP + +L F++K G +VVHCSAGVGRTGT++V+D+
Sbjct: 1889 RVVTQYHYTQWPDMGVPEYSLPVLTFVRKAAYAKRHAVGPVVVHCSAGVGRTGTYIVLDS 1948
Query: 449 MLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETH 508
ML + E V+++GF+ IR+QR +VQT+ QYVFI+ L+E L +TE+ L++H
Sbjct: 1949 MLQQIQHEGTVNIFGFLKHIRSQRNYLVQTEEQYVFIHDTLVEAILSKETEV----LDSH 2004
Query: 509 LQKIYNK--IPG-TSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNR 565
+ N IPG LE++F+ L+ IQ N +KNR IIP E +R
Sbjct: 2005 IHAYVNALLIPGPAGKTKLEKQFQLLSQSNIQQSDYSAALKQCNREKNRTSSIIPVERSR 2064
Query: 566 VIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTE 625
V I G E TDY+NAS+I GY Q + +I +Q PLLHTI+DFWRMIW+ + +VM+ +
Sbjct: 2065 VGISSLSG-EGTDYINASYIMGYYQSNEFIITQHPLLHTIKDFWRMIWDHNAQLVVMIPD 2123
Query: 626 LEERGQEKCAQYWPS-DGLVSYGDITVELKKEE-EC----ESYTVRDLLVTNTRENKSRQ 679
+ +++ YWP+ D ++ V L EE +C E ++D ++ T+++ +
Sbjct: 2124 GQNMAEDEFV-YWPNKDEPINCESFKVTLMAEEHKCLSNEEKLIIQDFILEATQDDYVLE 2182
Query: 680 IRQFHFHGWPEVGIP-SDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALST 738
+R F WP P S +IS+I K++ + + P+ VH G GTFCAL+T
Sbjct: 2183 VRHFQCPKWPNPDSPISKTFELISVI----KEEAANRDGPMIVHDEHGGVTAGTFCALTT 2238
Query: 739 VLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVV 779
++ +++ E +DV+Q K + L RP + +EQY+F YKV+
Sbjct: 2239 LMHQLEKENSVDVYQVAKMINLMRPGVFADIEQYQFLYKVI 2279
Score = 201 bits (510), Expect = 3e-51
Identities = 105/282 (37%), Positives = 167/282 (59%), Gaps = 19/282 (6%)
Query: 520 SNNGLEEEFKKLTSI--KIQNDKMRTG------NLPANMKKNRVLQIIPYEFNRVIIP-- 569
+++G EEF+ L ++Q+ + G N P N KNR + I+ Y+ +RV +
Sbjct: 1713 ASSGFTEEFETLKEFYQEVQSCTVDLGITADSSNHPDNKHKNRYINIVAYDHSRVKLAQL 1772
Query: 570 VKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEER 629
++ + TDY+NA+++DGY + +YIA+QGPL T EDFWRMIWE IVM+T L E+
Sbjct: 1773 AEKDGKLTDYINANYVDGYNRPKAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEK 1832
Query: 630 GQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQ--------IR 681
G+ KC QYWP+DG YG+ V K + YTVR+ + NT+ K Q +
Sbjct: 1833 GRRKCDQYWPADGSEEYGNFLVTQKSVQVLAYYTVRNFTLRNTKIKKGSQKGRPSGRVVT 1892
Query: 682 QFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLE 741
Q+H+ WP++G+P +++ + ++ + P+ VHCSAG GRTGT+ L ++L+
Sbjct: 1893 QYHYTQWPDMGVPEYSLPVLTFVRKAAYAKRHAVG-PVVVHCSAGVGRTGTYIVLDSMLQ 1951
Query: 742 RVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI 783
+++ EG +++F +K +R QR ++VQT EQY F + + E I
Sbjct: 1952 QIQHEGTVNIFGFLKHIRSQRNYLVQTEEQYVFIHDTLVEAI 1993
Score = 116 bits (291), Expect = 7e-26
Identities = 82/269 (30%), Positives = 130/269 (48%), Gaps = 12/269 (4%)
Query: 245 QATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAA 304
Q+ AA K+ N+EKNR +I+P + SRV ++ + G +DYINAS+I GY + N+FI
Sbjct: 2037 QSDYSAALKQCNREKNRTSSIIPVERSRVGISSLSG-EGTDYINASYIMGYYQSNEFIIT 2095
Query: 305 QGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQ----GCWTYGNIRVSV 360
Q P T+ DFWRMIW+ N +VM+ + + E + YWP++ C ++ + +
Sbjct: 2096 QHPLLHTIKDFWRMIWDHNAQLVVMIPDGQNMAEDEFV-YWPNKDEPINCESF-KVTLMA 2153
Query: 361 EDVTVLVDYTVRKFCIQQ-VGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVK 419
E+ L + K IQ + + T + F WP+ P + L + K +
Sbjct: 2154 EEHKCLSNE--EKLIIQDFILEATQDDYVLEVRHFQCPKWPNPDSPISKTFELISVIKEE 2211
Query: 420 ACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTD 479
A N G ++VH G GTF + ++ + E VDVY I R +
Sbjct: 2212 AANRD--GPMIVHDEHGGVTAGTFCALTTLMHQLEKENSVDVYQVAKMINLMRPGVFADI 2269
Query: 480 MQYVFIYQALLEHYLYGDTELEVTSLETH 508
QY F+Y+ +L E TSL+++
Sbjct: 2270 EQYQFLYKVILSLVSTRQEENPSTSLDSN 2298
>gi|194097398 protein tyrosine phosphatase, receptor type, G precursor
[Homo sapiens]
Length = 1445
Score = 404 bits (1039), Expect = e-112
Identities = 246/702 (35%), Positives = 381/702 (54%), Gaps = 54/702 (7%)
Query: 120 PWEGNSSTAATTPETFPPSDETPIIAVMVALSSLLVIVFIIIVLYML------------R 167
P E N+S + P P+I V AL+ + +I+ I +++Y R
Sbjct: 718 PAEKNTSGMISRPAPGRMEWIIPLIVVS-ALTFVCLILLIAVLVYWRGCNKIKSKGFPRR 776
Query: 168 FKKYKQAGSHSNS-----FRLSNGRTED------VEPQSVPLLARSPSTNRKYPPLPVDK 216
F++ +G F+ ++ ED V +S+P++ +PV +
Sbjct: 777 FREVPSSGERGEKGSRKCFQTAHFYVEDSSSPRVVPNESIPIIPIPDDMEA----IPVKQ 832
Query: 217 LEEEINRRMADDNKLFREEFNALPACP--IQATCEAASKEENKEKNRYVNILPYDHSRVH 274
+ I +++ F E+F + C + T E ++ ENK KNRY+NIL YDHSRV
Sbjct: 833 FVKHIGELYSNNQHGFSEDFEEVQRCTADMNITAEHSNHPENKHKNRYINILAYDHSRVK 892
Query: 275 LTPVEGVPD--SDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTN 332
L P+ G SDYINA++++GY + +IA QGP + T DFWRMIWEQNT IVM+TN
Sbjct: 893 LRPLPGKDSKHSDYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITN 952
Query: 333 LKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQ-------QVGDMTNR 385
L E+ KC QYWP + YGNI V+++ + YTVR+F I+ Q G+ R
Sbjct: 953 LVEKGRRKCDQYWPTENSEEYGNIIVTLKSTKIHACYTVRRFSIRNTKVKKGQKGNPKGR 1012
Query: 386 KPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVV 445
+ +R++ Q+H+T WPD GVP + +L F+++ A G ++VHCSAGVGRTGT++V
Sbjct: 1013 QNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPETGPVLVHCSAGVGRTGTYIV 1072
Query: 446 IDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSL 505
ID+ML + + V+V GF+ IR QR +VQT+ QY+FI+ ALLE L +TE+ L
Sbjct: 1073 IDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSNQL 1132
Query: 506 ETHLQKIYNKIPGT-SNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFN 564
+++ I IPG LE++FK +T + + + N +KNR ++P E
Sbjct: 1133 HSYVNSIL--IPGVGGKTRLEKQFKLVTQCNAKYVECFSAQKECNKEKNRNSSVVPSERA 1190
Query: 565 RVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLT 624
RV + G + TDY+NAS+I GY + + +I +Q PL HT +DFWRMIW+ + IVML
Sbjct: 1191 RVGLAPLPGMKGTDYINASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLP 1250
Query: 625 ELEERGQEKCAQYWPS-DGLVSYGDITVEL-KKEEEC----ESYTVRDLLVTNTRENKSR 678
+ + +++ YWPS + ++ TV L K+ C E + D ++ T+++
Sbjct: 1251 DNQSLAEDEFV-YWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVL 1309
Query: 679 QIRQFHFHGWPEVGIP-SDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALS 737
++R F WP P S +I++I K++ + + P VH GA G CAL+
Sbjct: 1310 EVRHFQCPKWPNPDAPISSTFELINVI----KEEALTRDGPTIVHDEYGAVSAGMLCALT 1365
Query: 738 TVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVV 779
T+ ++++ E +DVFQ K + L RP + +EQY+F YK +
Sbjct: 1366 TLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFIYKAM 1407
Score = 195 bits (495), Expect = 2e-49
Identities = 103/298 (34%), Positives = 168/298 (56%), Gaps = 19/298 (6%)
Query: 500 LEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQ-NDKMRTGNLPANMKKNRVLQI 558
+ V H+ ++Y+ + +G E+F+++ N N P N KNR + I
Sbjct: 828 IPVKQFVKHIGELYSN----NQHGFSEDFEEVQRCTADMNITAEHSNHPENKHKNRYINI 883
Query: 559 IPYEFNRVIIPVKRGEEN--TDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWK 616
+ Y+ +RV + G+++ +DY+NA+++DGY + +YIA+QGPL T EDFWRMIWE
Sbjct: 884 LAYDHSRVKLRPLPGKDSKHSDYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQN 943
Query: 617 SCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENK 676
+ IVM+T L E+G+ KC QYWP++ YG+I V LK + YTVR + NT+ K
Sbjct: 944 TGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIVTLKSTKIHACYTVRRFSIRNTKVKK 1003
Query: 677 S-----------RQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSA 725
R + Q+H+ WP++G+P +++ + + P+ VHCSA
Sbjct: 1004 GQKGNPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPETG-PVLVHCSA 1062
Query: 726 GAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI 783
G GRTGT+ + ++L+++K + ++V +K +R QR ++VQT EQY F + + E I
Sbjct: 1063 GVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAI 1120
Score = 113 bits (283), Expect = 6e-25
Identities = 77/264 (29%), Positives = 121/264 (45%), Gaps = 14/264 (5%)
Query: 234 EEFNALPACPIQ-ATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFI 292
++F + C + C +A KE NKEKNR +++P + +RV L P+ G+ +DYINAS+I
Sbjct: 1152 KQFKLVTQCNAKYVECFSAQKECNKEKNRNSSVVPSERARVGLAPLPGMKGTDYINASYI 1211
Query: 293 NGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQ---- 348
GY N+FI Q P T DFWRMIW+ N IVM+ + + E + YWP +
Sbjct: 1212 MGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFV-YWPSREESM 1270
Query: 349 GCWTYGNIRVSVEDVTVLVD--YTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPF 406
C + +S + + + + + F ++ D + + F WP+ P
Sbjct: 1271 NCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLE----VRHFQCPKWPNPDAPI 1326
Query: 407 TPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVS 466
+ L + K +A G +VH G G + + + E VDV+
Sbjct: 1327 SSTFELINVIKEEALTRD--GPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAK 1384
Query: 467 RIRAQRCQMVQTDMQYVFIYQALL 490
I R + QY FIY+A+L
Sbjct: 1385 MINLMRPGVFTDIEQYQFIYKAML 1408
>gi|110735404 protein tyrosine phosphatase, receptor type, U isoform 1
precursor [Homo sapiens]
Length = 1436
Score = 404 bits (1039), Expect = e-112
Identities = 214/586 (36%), Positives = 334/586 (56%), Gaps = 17/586 (2%)
Query: 205 TNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVN 264
T + +P + V L + IN+ + F++E+ + +A K++ + +R
Sbjct: 857 TGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESF-----FEGWDATKKKDKVKGSRQEP 911
Query: 265 ILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNT 324
+ YD RV L P+ G P++DYINA++I+GY N FIA QGPK E V DFWRM+W+++
Sbjct: 912 MPAYDRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHC 971
Query: 325 ATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTN 384
++IVM+T L E KC++YWP+ TYG+I++ + L +Y VR F +++ G
Sbjct: 972 SSIVMITKLVEVGRVKCSRYWPEDSD-TYGDIKIMLVKTETLAEYVVRTFALERRGYSAR 1030
Query: 385 RKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFV 444
+ + QFHFT+WP+ GVP+ G+L F+++VKA P AG IV+HCSAG GRTG ++
Sbjct: 1031 HE----VRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPIVIHCSAGTGRTGCYI 1086
Query: 445 VIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTS 504
V+D MLDM E VD+Y V + ++R M+QT+ QY+FI+ A+LE L G+T + V+
Sbjct: 1087 VLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGETTIPVSE 1146
Query: 505 LETHLQKIYNKIPGTSNNGLEEEFKKLTSI--KIQNDKMRTGNLPANMKKNRVLQIIPYE 562
+ +++ P ++++ L EEF+ L S+ + ++ LP N KNR + ++P +
Sbjct: 1147 FKATYKEMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPD 1206
Query: 563 FNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVM 622
+ G+ N +Y+NA+ D Y + ++I + PL T DFWR+++++ SIVM
Sbjct: 1207 RCLPFLISTDGDSN-NYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVM 1265
Query: 623 LTELEERGQE-KCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQ-- 679
L +L + C QYWP G YG + VE E R V N +
Sbjct: 1266 LNQLNQSNSAWPCLQYWPEPGRQQYGLMEVEFMSGTADEDLVARVFRVQNISRLQEGHLL 1325
Query: 680 IRQFHFHGWPEV-GIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALST 738
+R F F W P K + ++A V K Q +SG+ VHC G GR+GTFCA +T
Sbjct: 1326 VRHFQFLRWSAYRDTPDSKKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACAT 1385
Query: 739 VLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID 784
VLE ++ ++DVF K+LR +P+MV+T++QY FCY V EY++
Sbjct: 1386 VLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLE 1431
>gi|110735402 protein tyrosine phosphatase, receptor type, U isoform 3
precursor [Homo sapiens]
Length = 1446
Score = 404 bits (1039), Expect = e-112
Identities = 214/586 (36%), Positives = 334/586 (56%), Gaps = 17/586 (2%)
Query: 205 TNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVN 264
T + +P + V L + IN+ + F++E+ + +A K++ + +R
Sbjct: 867 TGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESF-----FEGWDATKKKDKVKGSRQEP 921
Query: 265 ILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNT 324
+ YD RV L P+ G P++DYINA++I+GY N FIA QGPK E V DFWRM+W+++
Sbjct: 922 MPAYDRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHC 981
Query: 325 ATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTN 384
++IVM+T L E KC++YWP+ TYG+I++ + L +Y VR F +++ G
Sbjct: 982 SSIVMITKLVEVGRVKCSRYWPEDSD-TYGDIKIMLVKTETLAEYVVRTFALERRGYSAR 1040
Query: 385 RKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFV 444
+ + QFHFT+WP+ GVP+ G+L F+++VKA P AG IV+HCSAG GRTG ++
Sbjct: 1041 HE----VRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPIVIHCSAGTGRTGCYI 1096
Query: 445 VIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTS 504
V+D MLDM E VD+Y V + ++R M+QT+ QY+FI+ A+LE L G+T + V+
Sbjct: 1097 VLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGETTIPVSE 1156
Query: 505 LETHLQKIYNKIPGTSNNGLEEEFKKLTSI--KIQNDKMRTGNLPANMKKNRVLQIIPYE 562
+ +++ P ++++ L EEF+ L S+ + ++ LP N KNR + ++P +
Sbjct: 1157 FKATYKEMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPD 1216
Query: 563 FNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVM 622
+ G+ N +Y+NA+ D Y + ++I + PL T DFWR+++++ SIVM
Sbjct: 1217 RCLPFLISTDGDSN-NYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVM 1275
Query: 623 LTELEERGQE-KCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQ-- 679
L +L + C QYWP G YG + VE E R V N +
Sbjct: 1276 LNQLNQSNSAWPCLQYWPEPGRQQYGLMEVEFMSGTADEDLVARVFRVQNISRLQEGHLL 1335
Query: 680 IRQFHFHGWPEV-GIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALST 738
+R F F W P K + ++A V K Q +SG+ VHC G GR+GTFCA +T
Sbjct: 1336 VRHFQFLRWSAYRDTPDSKKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACAT 1395
Query: 739 VLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID 784
VLE ++ ++DVF K+LR +P+MV+T++QY FCY V EY++
Sbjct: 1396 VLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLE 1441
>gi|110735406 protein tyrosine phosphatase, receptor type, U isoform 2
precursor [Homo sapiens]
Length = 1442
Score = 398 bits (1022), Expect = e-110
Identities = 214/592 (36%), Positives = 334/592 (56%), Gaps = 23/592 (3%)
Query: 205 TNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVN 264
T + +P + V L + IN+ + F++E+ + +A K++ + +R
Sbjct: 857 TGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESF-----FEGWDATKKKDKVKGSRQEP 911
Query: 265 ILPYDHSRVHLTPVEGVPDSDYINASFIN------GYQEKNKFIAAQGPKEETVNDFWRM 318
+ YD RV L P+ G P++DYINA++I+ GY N FIA QGPK E V DFWRM
Sbjct: 912 MPAYDRHRVKLHPMLGDPNADYINANYIDIRINREGYHRSNHFIATQGPKPEMVYDFWRM 971
Query: 319 IWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQ 378
+W+++ ++IVM+T L E KC++YWP+ TYG+I++ + L +Y VR F +++
Sbjct: 972 VWQEHCSSIVMITKLVEVGRVKCSRYWPEDSD-TYGDIKIMLVKTETLAEYVVRTFALER 1030
Query: 379 VGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVG 438
G + + QFHFT+WP+ GVP+ G+L F+++VKA P AG IV+HCSAG G
Sbjct: 1031 RGYSARHE----VRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPIVIHCSAGTG 1086
Query: 439 RTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDT 498
RTG ++V+D MLDM E VD+Y V + ++R M+QT+ QY+FI+ A+LE L G+T
Sbjct: 1087 RTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGET 1146
Query: 499 ELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSI--KIQNDKMRTGNLPANMKKNRVL 556
+ V+ + +++ P ++++ L EEF+ L S+ + ++ LP N KNR +
Sbjct: 1147 TIPVSEFKATYKEMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSM 1206
Query: 557 QIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWK 616
++P + + G+ N +Y+NA+ D Y + ++I + PL T DFWR+++++
Sbjct: 1207 DVLPPDRCLPFLISTDGDSN-NYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYG 1265
Query: 617 SCSIVMLTELEERGQE-KCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTREN 675
SIVML +L + C QYWP G YG + VE E R V N
Sbjct: 1266 CTSIVMLNQLNQSNSAWPCLQYWPEPGRQQYGLMEVEFMSGTADEDLVARVFRVQNISRL 1325
Query: 676 KSRQ--IRQFHFHGWPEV-GIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGT 732
+ +R F F W P K + ++A V K Q +SG+ VHC G GR+GT
Sbjct: 1326 QEGHLLVRHFQFLRWSAYRDTPDSKKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGT 1385
Query: 733 FCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID 784
FCA +TVLE ++ ++DVF K+LR +P+MV+T++QY FCY V EY++
Sbjct: 1386 FCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLE 1437
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,842,143
Number of Sequences: 37866
Number of extensions: 1354308
Number of successful extensions: 6071
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 136
Number of HSP's successfully gapped in prelim test: 69
Number of HSP's that attempted gapping in prelim test: 4117
Number of HSP's gapped (non-prelim): 944
length of query: 793
length of database: 18,247,518
effective HSP length: 110
effective length of query: 683
effective length of database: 14,082,258
effective search space: 9618182214
effective search space used: 9618182214
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.