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Search of human proteins with 18375660
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18375660 protein tyrosine phosphatase, non-receptor type 7
isoform 2 [Homo sapiens]
(399 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18375660 protein tyrosine phosphatase, non-receptor type 7 is... 823 0.0
gi|18375658 protein tyrosine phosphatase, non-receptor type 7 is... 742 0.0
gi|4506325 protein tyrosine phosphatase, receptor type, R isofor... 382 e-106
gi|19743917 protein tyrosine phosphatase, receptor type, R isofo... 382 e-106
gi|90652861 protein-tyrosine-phosphatase non-receptor 5 isoform ... 332 3e-91
gi|90652859 protein-tyrosine-phosphatase non-receptor 5 isoform ... 332 3e-91
gi|90652853 protein-tyrosine-phosphatase non-receptor 5 isoform ... 332 3e-91
gi|13677222 receptor-type protein tyrosine phosphatase O isoform... 191 8e-49
gi|13677220 receptor-type protein tyrosine phosphatase O isoform... 191 8e-49
gi|13677218 receptor-type protein tyrosine phosphatase O isoform... 191 8e-49
gi|13677216 receptor-type protein tyrosine phosphatase O isoform... 191 8e-49
gi|13677214 receptor-type protein tyrosine phosphatase O isoform... 191 8e-49
gi|4506323 receptor-type protein tyrosine phosphatase O isoform ... 191 8e-49
gi|18860902 protein tyrosine phosphatase, receptor type, K isofo... 191 1e-48
gi|157952215 protein tyrosine phosphatase, receptor type, B isof... 188 8e-48
gi|157952213 protein tyrosine phosphatase, receptor type, B isof... 188 8e-48
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 187 2e-47
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 186 4e-47
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 186 4e-47
gi|148539860 protein tyrosine phosphatase, receptor type, T isof... 185 5e-47
gi|148539858 protein tyrosine phosphatase, receptor type, T isof... 185 5e-47
gi|208431815 protein tyrosine phosphatase, receptor type, K isof... 184 9e-47
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ... 184 2e-46
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 184 2e-46
gi|104487295 protein tyrosine phosphatase, receptor type, sigma ... 184 2e-46
gi|18641364 protein tyrosine phosphatase, receptor type, C isofo... 184 2e-46
gi|18641347 protein tyrosine phosphatase, receptor type, C isofo... 184 2e-46
gi|18641362 protein tyrosine phosphatase, receptor type, C isofo... 184 2e-46
gi|104487002 protein tyrosine phosphatase, receptor type, D isof... 181 8e-46
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 181 8e-46
>gi|18375660 protein tyrosine phosphatase, non-receptor type 7
isoform 2 [Homo sapiens]
Length = 399
Score = 823 bits (2125), Expect = 0.0
Identities = 399/399 (100%), Positives = 399/399 (100%)
Query: 1 MGASFWPIRQAREQQRRALSFRQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLTLSLGAA 60
MGASFWPIRQAREQQRRALSFRQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLTLSLGAA
Sbjct: 1 MGASFWPIRQAREQQRRALSFRQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLTLSLGAA 60
Query: 61 MTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHP 120
MTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHP
Sbjct: 61 MTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHP 120
Query: 121 LTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRA 180
LTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRA
Sbjct: 121 LTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRA 180
Query: 181 QSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGK 240
QSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGK
Sbjct: 181 QSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGK 240
Query: 241 EKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTP 300
EKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTP
Sbjct: 241 EKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTP 300
Query: 301 ESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILG 360
ESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILG
Sbjct: 301 ESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILG 360
Query: 361 IVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP 399
IVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
Sbjct: 361 IVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP 399
>gi|18375658 protein tyrosine phosphatase, non-receptor type 7
isoform 1 [Homo sapiens]
Length = 360
Score = 742 bits (1915), Expect = 0.0
Identities = 360/360 (100%), Positives = 360/360 (100%)
Query: 40 MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP 99
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
Sbjct: 1 MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP 60
Query: 100 ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA 159
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
Sbjct: 61 ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA 120
Query: 160 SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW 219
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
Sbjct: 121 SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW 180
Query: 220 EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY 279
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
Sbjct: 181 EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY 240
Query: 280 QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC 339
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
Sbjct: 241 QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC 300
Query: 340 FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP 399
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
Sbjct: 301 FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP 360
>gi|4506325 protein tyrosine phosphatase, receptor type, R isoform 1
precursor [Homo sapiens]
Length = 657
Score = 382 bits (982), Expect = e-106
Identities = 192/353 (54%), Positives = 246/353 (69%), Gaps = 7/353 (1%)
Query: 47 RSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTP 106
+ R P + A P P K K + LQERRGSNV+L LD+ SLG +EP S+ TP
Sbjct: 306 QGRGAPEIRATTATSVCPSPFKM---KPIGLQERRGSNVSLTLDMSSLGNIEPFVSIPTP 362
Query: 107 RE-VTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYK 165
RE V + +L++A LTR L+ S L+ EF++IP NFV P+++DIP H +K+RYK
Sbjct: 363 REKVAMEYLQSASRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYK 422
Query: 166 TILPNPQSRVCLGRAQSQEDG--DYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVW 223
TILPNP SRVCL R ++ D YINANYIRGY GKEK +IATQGPM NTV DFW+MVW
Sbjct: 423 TILPNPLSRVCL-RPKNVTDSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVW 481
Query: 224 QEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEER 283
QE+ +IVM+T+L+E EKCV YWP + YG ++ + + EC YT+R L ++
Sbjct: 482 QEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVISVNECDNYTIRNLVLKQGSHT 541
Query: 284 RSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIAT 343
+ VKH +++WPDH+TP+SA PLL+L+ +VEE + GP+VVHCSAGIGRTGCFIAT
Sbjct: 542 QHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIAT 601
Query: 344 RIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEE 396
IGCQQLK G VD L IVCQLR+DRGGM+QT+EQY+F+HH L LY +L E
Sbjct: 602 SIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLYESRLSAE 654
>gi|19743917 protein tyrosine phosphatase, receptor type, R isoform
2 [Homo sapiens]
Length = 412
Score = 382 bits (982), Expect = e-106
Identities = 192/353 (54%), Positives = 246/353 (69%), Gaps = 7/353 (1%)
Query: 47 RSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTP 106
+ R P + A P P K K + LQERRGSNV+L LD+ SLG +EP S+ TP
Sbjct: 61 QGRGAPEIRATTATSVCPSPFKM---KPIGLQERRGSNVSLTLDMSSLGNIEPFVSIPTP 117
Query: 107 RE-VTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYK 165
RE V + +L++A LTR L+ S L+ EF++IP NFV P+++DIP H +K+RYK
Sbjct: 118 REKVAMEYLQSASRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYK 177
Query: 166 TILPNPQSRVCLGRAQSQEDG--DYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVW 223
TILPNP SRVCL R ++ D YINANYIRGY GKEK +IATQGPM NTV DFW+MVW
Sbjct: 178 TILPNPLSRVCL-RPKNVTDSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVW 236
Query: 224 QEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEER 283
QE+ +IVM+T+L+E EKCV YWP + YG ++ + + EC YT+R L ++
Sbjct: 237 QEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVISVNECDNYTIRNLVLKQGSHT 296
Query: 284 RSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIAT 343
+ VKH +++WPDH+TP+SA PLL+L+ +VEE + GP+VVHCSAGIGRTGCFIAT
Sbjct: 297 QHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIAT 356
Query: 344 RIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEE 396
IGCQQLK G VD L IVCQLR+DRGGM+QT+EQY+F+HH L LY +L E
Sbjct: 357 SIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLYESRLSAE 409
>gi|90652861 protein-tyrosine-phosphatase non-receptor 5 isoform b
[Homo sapiens]
Length = 533
Score = 332 bits (852), Expect = 3e-91
Identities = 184/401 (45%), Positives = 238/401 (59%), Gaps = 26/401 (6%)
Query: 7 PIRQAREQQRRALSFRQTSWLSEP------PLGPAPHLSMVQAHGG-RSRAQPLTLSLGA 59
P R+ R SF + W+ E L P P + + A P +L++
Sbjct: 145 PPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTV-- 202
Query: 60 AMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP-ICSVNTPREVTLH-FLRTA 117
K + LQERRGSNV+L LD+ + G E + +PRE + +L +A
Sbjct: 203 -------------KSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSA 249
Query: 118 GHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCL 177
L L + P L+ EF +IP NFV P++ DIPG K+RYKTILPNP SRVCL
Sbjct: 250 SRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCL 309
Query: 178 GRAQSQED-GDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQL 236
+ YINANYIRGY G+EKVYIATQGP+ +TV+DFW MVWQE +IVM+T +
Sbjct: 310 TSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNI 369
Query: 237 REGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPD 296
E EKC YWP E+ Y +I +Q + +Y +R ++++ E R +KH F++WPD
Sbjct: 370 EEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPD 429
Query: 297 HQTPESAGPLLRLVAEVEE-SPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGE 355
+TP+ A PLL LV EVEE + + H PI+VHCSAGIGRTGCFIAT I CQQL+ G
Sbjct: 430 QKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGV 489
Query: 356 VDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEE 396
VDIL CQLR DRGGMIQT EQYQF+HH ++LY QL +
Sbjct: 490 VDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQ 530
>gi|90652859 protein-tyrosine-phosphatase non-receptor 5 isoform a
[Homo sapiens]
Length = 565
Score = 332 bits (852), Expect = 3e-91
Identities = 184/401 (45%), Positives = 238/401 (59%), Gaps = 26/401 (6%)
Query: 7 PIRQAREQQRRALSFRQTSWLSEP------PLGPAPHLSMVQAHGG-RSRAQPLTLSLGA 59
P R+ R SF + W+ E L P P + + A P +L++
Sbjct: 177 PPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTV-- 234
Query: 60 AMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP-ICSVNTPREVTLH-FLRTA 117
K + LQERRGSNV+L LD+ + G E + +PRE + +L +A
Sbjct: 235 -------------KSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSA 281
Query: 118 GHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCL 177
L L + P L+ EF +IP NFV P++ DIPG K+RYKTILPNP SRVCL
Sbjct: 282 SRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCL 341
Query: 178 GRAQSQED-GDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQL 236
+ YINANYIRGY G+EKVYIATQGP+ +TV+DFW MVWQE +IVM+T +
Sbjct: 342 TSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNI 401
Query: 237 REGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPD 296
E EKC YWP E+ Y +I +Q + +Y +R ++++ E R +KH F++WPD
Sbjct: 402 EEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPD 461
Query: 297 HQTPESAGPLLRLVAEVEE-SPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGE 355
+TP+ A PLL LV EVEE + + H PI+VHCSAGIGRTGCFIAT I CQQL+ G
Sbjct: 462 QKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGV 521
Query: 356 VDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEE 396
VDIL CQLR DRGGMIQT EQYQF+HH ++LY QL +
Sbjct: 522 VDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQ 562
>gi|90652853 protein-tyrosine-phosphatase non-receptor 5 isoform a
[Homo sapiens]
Length = 565
Score = 332 bits (852), Expect = 3e-91
Identities = 184/401 (45%), Positives = 238/401 (59%), Gaps = 26/401 (6%)
Query: 7 PIRQAREQQRRALSFRQTSWLSEP------PLGPAPHLSMVQAHGG-RSRAQPLTLSLGA 59
P R+ R SF + W+ E L P P + + A P +L++
Sbjct: 177 PPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTV-- 234
Query: 60 AMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP-ICSVNTPREVTLH-FLRTA 117
K + LQERRGSNV+L LD+ + G E + +PRE + +L +A
Sbjct: 235 -------------KSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSA 281
Query: 118 GHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCL 177
L L + P L+ EF +IP NFV P++ DIPG K+RYKTILPNP SRVCL
Sbjct: 282 SRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCL 341
Query: 178 GRAQSQED-GDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQL 236
+ YINANYIRGY G+EKVYIATQGP+ +TV+DFW MVWQE +IVM+T +
Sbjct: 342 TSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNI 401
Query: 237 REGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPD 296
E EKC YWP E+ Y +I +Q + +Y +R ++++ E R +KH F++WPD
Sbjct: 402 EEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPD 461
Query: 297 HQTPESAGPLLRLVAEVEE-SPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGE 355
+TP+ A PLL LV EVEE + + H PI+VHCSAGIGRTGCFIAT I CQQL+ G
Sbjct: 462 QKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGV 521
Query: 356 VDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEE 396
VDIL CQLR DRGGMIQT EQYQF+HH ++LY QL +
Sbjct: 522 VDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQ 562
>gi|13677222 receptor-type protein tyrosine phosphatase O isoform c
precursor [Homo sapiens]
Length = 405
Score = 191 bits (486), Expect = 8e-49
Identities = 108/258 (41%), Positives = 151/258 (58%), Gaps = 8/258 (3%)
Query: 136 LEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIR 195
L+ E LK+ + D+P + K+RY ILP SRV L +E DYINANYI
Sbjct: 129 LQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIP 188
Query: 196 GYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKE-KCVHYWPTEEE-- 252
GY+ ++ YIATQGP+P T +DFW+MV Q++ +IVMLTQ E + KC HYWP EE
Sbjct: 189 GYNSPQE-YIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI 247
Query: 253 TYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTP--ESAGPLLRLV 310
YG + + +E ++ R I Y +E + V H ++AWPDH P +A +L+ V
Sbjct: 248 AYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFV 307
Query: 311 AEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRG 370
V + + GP+++HCSAG+GRTG FIA Q ++ VDILG+V ++R R
Sbjct: 308 HMVRQ--QATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRM 365
Query: 371 GMIQTAEQYQFLHHTLAL 388
M+QT EQY F+H + L
Sbjct: 366 SMVQTEEQYIFIHQCVQL 383
>gi|13677220 receptor-type protein tyrosine phosphatase O isoform d
precursor [Homo sapiens]
Length = 377
Score = 191 bits (486), Expect = 8e-49
Identities = 108/258 (41%), Positives = 151/258 (58%), Gaps = 8/258 (3%)
Query: 136 LEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIR 195
L+ E LK+ + D+P + K+RY ILP SRV L +E DYINANYI
Sbjct: 101 LQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIP 160
Query: 196 GYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKE-KCVHYWPTEEE-- 252
GY+ ++ YIATQGP+P T +DFW+MV Q++ +IVMLTQ E + KC HYWP EE
Sbjct: 161 GYNSPQE-YIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI 219
Query: 253 TYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTP--ESAGPLLRLV 310
YG + + +E ++ R I Y +E + V H ++AWPDH P +A +L+ V
Sbjct: 220 AYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFV 279
Query: 311 AEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRG 370
V + + GP+++HCSAG+GRTG FIA Q ++ VDILG+V ++R R
Sbjct: 280 HMVRQ--QATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRM 337
Query: 371 GMIQTAEQYQFLHHTLAL 388
M+QT EQY F+H + L
Sbjct: 338 SMVQTEEQYIFIHQCVQL 355
>gi|13677218 receptor-type protein tyrosine phosphatase O isoform c
precursor [Homo sapiens]
Length = 405
Score = 191 bits (486), Expect = 8e-49
Identities = 108/258 (41%), Positives = 151/258 (58%), Gaps = 8/258 (3%)
Query: 136 LEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIR 195
L+ E LK+ + D+P + K+RY ILP SRV L +E DYINANYI
Sbjct: 129 LQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIP 188
Query: 196 GYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKE-KCVHYWPTEEE-- 252
GY+ ++ YIATQGP+P T +DFW+MV Q++ +IVMLTQ E + KC HYWP EE
Sbjct: 189 GYNSPQE-YIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI 247
Query: 253 TYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTP--ESAGPLLRLV 310
YG + + +E ++ R I Y +E + V H ++AWPDH P +A +L+ V
Sbjct: 248 AYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFV 307
Query: 311 AEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRG 370
V + + GP+++HCSAG+GRTG FIA Q ++ VDILG+V ++R R
Sbjct: 308 HMVRQ--QATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRM 365
Query: 371 GMIQTAEQYQFLHHTLAL 388
M+QT EQY F+H + L
Sbjct: 366 SMVQTEEQYIFIHQCVQL 383
>gi|13677216 receptor-type protein tyrosine phosphatase O isoform d
precursor [Homo sapiens]
Length = 377
Score = 191 bits (486), Expect = 8e-49
Identities = 108/258 (41%), Positives = 151/258 (58%), Gaps = 8/258 (3%)
Query: 136 LEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIR 195
L+ E LK+ + D+P + K+RY ILP SRV L +E DYINANYI
Sbjct: 101 LQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIP 160
Query: 196 GYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKE-KCVHYWPTEEE-- 252
GY+ ++ YIATQGP+P T +DFW+MV Q++ +IVMLTQ E + KC HYWP EE
Sbjct: 161 GYNSPQE-YIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI 219
Query: 253 TYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTP--ESAGPLLRLV 310
YG + + +E ++ R I Y +E + V H ++AWPDH P +A +L+ V
Sbjct: 220 AYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFV 279
Query: 311 AEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRG 370
V + + GP+++HCSAG+GRTG FIA Q ++ VDILG+V ++R R
Sbjct: 280 HMVRQ--QATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRM 337
Query: 371 GMIQTAEQYQFLHHTLAL 388
M+QT EQY F+H + L
Sbjct: 338 SMVQTEEQYIFIHQCVQL 355
>gi|13677214 receptor-type protein tyrosine phosphatase O isoform a
precursor [Homo sapiens]
Length = 1216
Score = 191 bits (486), Expect = 8e-49
Identities = 108/258 (41%), Positives = 151/258 (58%), Gaps = 8/258 (3%)
Query: 136 LEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIR 195
L+ E LK+ + D+P + K+RY ILP SRV L +E DYINANYI
Sbjct: 940 LQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIP 999
Query: 196 GYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKE-KCVHYWPTEEE-- 252
GY+ ++ YIATQGP+P T +DFW+MV Q++ +IVMLTQ E + KC HYWP EE
Sbjct: 1000 GYNSPQE-YIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI 1058
Query: 253 TYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTP--ESAGPLLRLV 310
YG + + +E ++ R I Y +E + V H ++AWPDH P +A +L+ V
Sbjct: 1059 AYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFV 1118
Query: 311 AEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRG 370
V + + GP+++HCSAG+GRTG FIA Q ++ VDILG+V ++R R
Sbjct: 1119 HMVRQ--QATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRM 1176
Query: 371 GMIQTAEQYQFLHHTLAL 388
M+QT EQY F+H + L
Sbjct: 1177 SMVQTEEQYIFIHQCVQL 1194
>gi|4506323 receptor-type protein tyrosine phosphatase O isoform b
precursor [Homo sapiens]
Length = 1188
Score = 191 bits (486), Expect = 8e-49
Identities = 108/258 (41%), Positives = 151/258 (58%), Gaps = 8/258 (3%)
Query: 136 LEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIR 195
L+ E LK+ + D+P + K+RY ILP SRV L +E DYINANYI
Sbjct: 912 LQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIP 971
Query: 196 GYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKE-KCVHYWPTEEE-- 252
GY+ ++ YIATQGP+P T +DFW+MV Q++ +IVMLTQ E + KC HYWP EE
Sbjct: 972 GYNSPQE-YIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI 1030
Query: 253 TYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTP--ESAGPLLRLV 310
YG + + +E ++ R I Y +E + V H ++AWPDH P +A +L+ V
Sbjct: 1031 AYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFV 1090
Query: 311 AEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRG 370
V + + GP+++HCSAG+GRTG FIA Q ++ VDILG+V ++R R
Sbjct: 1091 HMVRQ--QATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRM 1148
Query: 371 GMIQTAEQYQFLHHTLAL 388
M+QT EQY F+H + L
Sbjct: 1149 SMVQTEEQYIFIHQCVQL 1166
>gi|18860902 protein tyrosine phosphatase, receptor type, K isoform b
[Homo sapiens]
Length = 1440
Score = 191 bits (484), Expect = 1e-48
Identities = 105/230 (45%), Positives = 133/230 (57%), Gaps = 6/230 (2%)
Query: 160 SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW 219
+K+RY I+ SRV L + DYINANYI GY + YIATQGP+ TV DFW
Sbjct: 913 AKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQ-RPSHYIATQGPVHETVYDFW 971
Query: 220 EMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQ 278
M+WQE+ + IVM+T L E G+ KC YWP + E YG F++ +M+ EY VR T++
Sbjct: 972 RMIWQEQSACIVMVTNLVEVGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVVRTFTLE 1031
Query: 279 YQ--EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGR 336
+ E R VK F+ WPDH P A LL + V+ S +A GPIVVHCSAG GR
Sbjct: 1032 RRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPSA--GPIVVHCSAGAGR 1089
Query: 337 TGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTL 386
TGC+I I + G VDI V LR R M+QT EQY F+H +
Sbjct: 1090 TGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAI 1139
Score = 103 bits (258), Expect = 2e-22
Identities = 83/269 (30%), Positives = 128/269 (47%), Gaps = 21/269 (7%)
Query: 136 LEEEFLKIPSNFVSP----EDLDI---PGHASKDRYKTILPNPQSRVCLGRAQSQEDGDY 188
L++EF + N V+P ED I P + K+R+ +LP + L E +Y
Sbjct: 1174 LKDEFQTL--NSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDG-ESSNY 1230
Query: 189 INANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWP 248
INA + Y + +I TQ P+PNTV DFW +V+ + IVML ++ + + C YWP
Sbjct: 1231 INAALMDSYR-QPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEV-DLSQGCPQYWP 1288
Query: 249 TEEET-YGPFQIRIQDMK-ECPE----YTVRQLTIQYQEERRSVKHILFSAWPDH-QTPE 301
E YGP Q+ +C + + LT + QE V+ + W H + P
Sbjct: 1289 EEGMLRYGPIQVECMSCSMDCDVINRIFRICNLT-RPQEGYLMVQQFQYLGWASHREVPG 1347
Query: 302 SAGPLLRLVAEVEESPETAAH-PGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILG 360
S L+L+ +VE+ E G ++HC G GR+G F A I + +K + VD+
Sbjct: 1348 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1407
Query: 361 IVCQLRLDRGGMIQTAEQYQFLHHTLALY 389
V LR + M++ EQY+F + Y
Sbjct: 1408 AVKTLRNSKPNMVEAPEQYRFCYDVALEY 1436
>gi|157952215 protein tyrosine phosphatase, receptor type, B isoform a
[Homo sapiens]
Length = 2215
Score = 188 bits (477), Expect = 8e-48
Identities = 99/235 (42%), Positives = 141/235 (60%), Gaps = 7/235 (2%)
Query: 155 IPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNT 214
+P + K+RY ILP +RV L DYINA+YI G + + + YI TQGP+P T
Sbjct: 1942 LPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRRE-YIVTQGPLPGT 2000
Query: 215 VSDFWEMVWQEEVSLIVMLTQ-LREGKEKCVHYWPTEEET--YGPFQIRIQDMKECPEYT 271
DFW+MVW++ V IVM+TQ + +G+ KC HYWP ++++ YG +++ PE+T
Sbjct: 2001 KDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWT 2060
Query: 272 VRQLTIQYQEE---RRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVV 328
+R+ I +E+ R ++H ++ WPDH PE+ L++ V V + + GP VV
Sbjct: 2061 IREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVV 2120
Query: 329 HCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLH 383
HCSAG+GRTG FIA QQL ++ VDI G V LRL R M+QT QY +LH
Sbjct: 2121 HCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLH 2175
>gi|157952213 protein tyrosine phosphatase, receptor type, B isoform b
precursor [Homo sapiens]
Length = 1997
Score = 188 bits (477), Expect = 8e-48
Identities = 99/235 (42%), Positives = 141/235 (60%), Gaps = 7/235 (2%)
Query: 155 IPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNT 214
+P + K+RY ILP +RV L DYINA+YI G + + + YI TQGP+P T
Sbjct: 1724 LPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRRE-YIVTQGPLPGT 1782
Query: 215 VSDFWEMVWQEEVSLIVMLTQ-LREGKEKCVHYWPTEEET--YGPFQIRIQDMKECPEYT 271
DFW+MVW++ V IVM+TQ + +G+ KC HYWP ++++ YG +++ PE+T
Sbjct: 1783 KDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWT 1842
Query: 272 VRQLTIQYQEE---RRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVV 328
+R+ I +E+ R ++H ++ WPDH PE+ L++ V V + + GP VV
Sbjct: 1843 IREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVV 1902
Query: 329 HCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLH 383
HCSAG+GRTG FIA QQL ++ VDI G V LRL R M+QT QY +LH
Sbjct: 1903 HCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLH 1957
>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
isoform 1 precursor [Homo sapiens]
Length = 1948
Score = 187 bits (474), Expect = 2e-47
Identities = 112/310 (36%), Positives = 160/310 (51%), Gaps = 15/310 (4%)
Query: 89 LDVRSLGAVEPICSVNTP-REVTLHFLRTAGHP------LTRWALQRQPPSPKQLEEEFL 141
+++R + P + +P RE HF HP + + + +L +E+
Sbjct: 1339 VEMRRINFQTPDSGLRSPLREPGFHFESMLSHPPIPIADMAEHTERLKANDSLKLSQEYE 1398
Query: 142 KI-PSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGK 200
I P + E ++ + K+RY ++ SRV L + DYINANY+ GY
Sbjct: 1399 SIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRC- 1457
Query: 201 EKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTE-EETYGPFQ 258
+ YIATQGP+P T DFW MVW++ + IVM+T+L E + KC YWP ETYG Q
Sbjct: 1458 QNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQ 1517
Query: 259 IRIQDMKECPEYTVRQLTIQYQ--EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEES 316
+ + D E + VR ++ E+R V+ F+AWPDH PE P L + V+
Sbjct: 1518 VTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTC 1577
Query: 317 PETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTA 376
A GPIVVHCSAG+GRTGCFI +++K VD+ G V +R R M+QT
Sbjct: 1578 NPPDA--GPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTE 1635
Query: 377 EQYQFLHHTL 386
+QY F+H L
Sbjct: 1636 DQYSFIHEAL 1645
Score = 181 bits (458), Expect = 1e-45
Identities = 97/251 (38%), Positives = 142/251 (56%), Gaps = 8/251 (3%)
Query: 145 SNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVY 204
S F+S ++P + K+R I+P +RVCL + E DYINA++I GY ++K Y
Sbjct: 1695 SRFISA---NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYR-QQKAY 1750
Query: 205 IATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEET-YGPFQIRIQ 262
IATQGP+ T DFW M+W+ +++VMLT+LRE G+EKC YWP E Y F +
Sbjct: 1751 IATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPM 1810
Query: 263 DMKECPEYTVRQ--LTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETA 320
P+Y +R+ +T + R+V+ F+ WP+ P+S + + +V ++ E
Sbjct: 1811 AEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQF 1870
Query: 321 AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQ 380
GPI VHCSAG+GRTG FI I ++++ G VDI V LR R M+QT ++YQ
Sbjct: 1871 GQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQ 1930
Query: 381 FLHHTLALYAG 391
F + Y G
Sbjct: 1931 FCYQAALEYLG 1941
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 186 bits (471), Expect = 4e-47
Identities = 100/240 (41%), Positives = 135/240 (56%), Gaps = 7/240 (2%)
Query: 151 EDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGP 210
E+ ++ + K+RY ++ SRV L DYINANYI GY K+ YIATQGP
Sbjct: 1368 ENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYR-KQNAYIATQGP 1426
Query: 211 MPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTE-EETYGPFQIRIQDMKECP 268
+P T+ DFW MVW++ + +VM+T+L E + KC YWP ET G Q+ + D E
Sbjct: 1427 LPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELA 1486
Query: 269 EYTVRQLTIQYQ--EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPI 326
YTVR + E+R ++ F AWPDH PE P+L + V+ A GP+
Sbjct: 1487 TYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDA--GPM 1544
Query: 327 VVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTL 386
VVHCSAG+GRTGCFI +++K VDI G V +R R M+QT +QY F+H L
Sbjct: 1545 VVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEAL 1604
Score = 174 bits (442), Expect = 1e-43
Identities = 93/251 (37%), Positives = 141/251 (56%), Gaps = 8/251 (3%)
Query: 145 SNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVY 204
S F+S ++P + K+R I+P +RVCL + E DYINA+++ GY ++K Y
Sbjct: 1654 SRFISA---NLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYR-QQKAY 1709
Query: 205 IATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEET-YGPFQIRIQ 262
IATQGP+ + DFW M+W+ ++IVMLT+LRE G+EKC YWP E Y F +
Sbjct: 1710 IATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPM 1769
Query: 263 DMKECPEYTVRQ--LTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETA 320
P+Y +R+ +T + R+++ F+ WP+ P++ + + +V ++ E
Sbjct: 1770 AEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQF 1829
Query: 321 AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQ 380
GPI VHCSAG+GRTG FI I ++++ G VD+ V LR R M+QT +QYQ
Sbjct: 1830 GQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQ 1889
Query: 381 FLHHTLALYAG 391
+ Y G
Sbjct: 1890 LCYRAALEYLG 1900
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 186 bits (471), Expect = 4e-47
Identities = 100/240 (41%), Positives = 135/240 (56%), Gaps = 7/240 (2%)
Query: 151 EDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGP 210
E+ ++ + K+RY ++ SRV L DYINANYI GY K+ YIATQGP
Sbjct: 1359 ENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYR-KQNAYIATQGP 1417
Query: 211 MPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTE-EETYGPFQIRIQDMKECP 268
+P T+ DFW MVW++ + +VM+T+L E + KC YWP ET G Q+ + D E
Sbjct: 1418 LPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELA 1477
Query: 269 EYTVRQLTIQYQ--EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPI 326
YTVR + E+R ++ F AWPDH PE P+L + V+ A GP+
Sbjct: 1478 TYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDA--GPM 1535
Query: 327 VVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTL 386
VVHCSAG+GRTGCFI +++K VDI G V +R R M+QT +QY F+H L
Sbjct: 1536 VVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEAL 1595
Score = 174 bits (442), Expect = 1e-43
Identities = 93/251 (37%), Positives = 141/251 (56%), Gaps = 8/251 (3%)
Query: 145 SNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVY 204
S F+S ++P + K+R I+P +RVCL + E DYINA+++ GY ++K Y
Sbjct: 1645 SRFISA---NLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYR-QQKAY 1700
Query: 205 IATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEET-YGPFQIRIQ 262
IATQGP+ + DFW M+W+ ++IVMLT+LRE G+EKC YWP E Y F +
Sbjct: 1701 IATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPM 1760
Query: 263 DMKECPEYTVRQ--LTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETA 320
P+Y +R+ +T + R+++ F+ WP+ P++ + + +V ++ E
Sbjct: 1761 AEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQF 1820
Query: 321 AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQ 380
GPI VHCSAG+GRTG FI I ++++ G VD+ V LR R M+QT +QYQ
Sbjct: 1821 GQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQ 1880
Query: 381 FLHHTLALYAG 391
+ Y G
Sbjct: 1881 LCYRAALEYLG 1891
>gi|148539860 protein tyrosine phosphatase, receptor type, T isoform 2
precursor [Homo sapiens]
Length = 1441
Score = 185 bits (470), Expect = 5e-47
Identities = 104/232 (44%), Positives = 134/232 (57%), Gaps = 10/232 (4%)
Query: 160 SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW 219
+K+RY I+ SRV L DYINANYI GY + + YIATQGPM TV DFW
Sbjct: 914 NKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYH-RPRHYIATQGPMQETVKDFW 972
Query: 220 EMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQ 278
M+WQE + IVM+T L E G+ KCV YWP + E YG ++ + + + EY +R T+Q
Sbjct: 973 RMIWQENSASIVMVTNLVEVGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQ 1032
Query: 279 YQ--EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVE--ESPETAAHPGPIVVHCSAGI 334
+ E R ++ F++WPDH P A LL V +V+ PE GPIVVHCSAG
Sbjct: 1033 KKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEA----GPIVVHCSAGA 1088
Query: 335 GRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTL 386
GRTGCFIA + G VDI V +LR R ++QT EQY F+H +
Sbjct: 1089 GRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAI 1140
Score = 120 bits (302), Expect = 2e-27
Identities = 84/267 (31%), Positives = 140/267 (52%), Gaps = 15/267 (5%)
Query: 135 QLEEEF--LKIPSNFVSPEDLDI---PGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYI 189
Q+++EF L I + V PED I P + K+R +LP + L E +YI
Sbjct: 1174 QIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDG-ESSNYI 1232
Query: 190 NANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPT 249
NA + + + ++ TQ P+PNTV+DFW +V+ S +VML ++ + + C+ YWP
Sbjct: 1233 NAALMDSHK-QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEM-DTAQFCMQYWPE 1290
Query: 250 EEE-TYGPFQIRI--QDMKECPEYTVRQLT--IQYQEERRSVKHILFSAWPDHQ-TPESA 303
+ YGP Q+ D+ E + + ++ + Q+ R V+H+ + WP ++ TP S
Sbjct: 1291 KTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSK 1350
Query: 304 GPLLRLVAEVEESPETA-AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIV 362
LL++V +E+ E G VVHC G GR+G F A C+ ++ + +D+ IV
Sbjct: 1351 RSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1410
Query: 363 CQLRLDRGGMIQTAEQYQFLHHTLALY 389
LR ++ M++T EQY+F++ Y
Sbjct: 1411 KTLRNNKSNMVETLEQYKFVYEVALEY 1437
>gi|148539858 protein tyrosine phosphatase, receptor type, T isoform 1
precursor [Homo sapiens]
Length = 1460
Score = 185 bits (470), Expect = 5e-47
Identities = 104/232 (44%), Positives = 134/232 (57%), Gaps = 10/232 (4%)
Query: 160 SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW 219
+K+RY I+ SRV L DYINANYI GY + + YIATQGPM TV DFW
Sbjct: 933 NKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYH-RPRHYIATQGPMQETVKDFW 991
Query: 220 EMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQ 278
M+WQE + IVM+T L E G+ KCV YWP + E YG ++ + + + EY +R T+Q
Sbjct: 992 RMIWQENSASIVMVTNLVEVGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQ 1051
Query: 279 YQ--EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVE--ESPETAAHPGPIVVHCSAGI 334
+ E R ++ F++WPDH P A LL V +V+ PE GPIVVHCSAG
Sbjct: 1052 KKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEA----GPIVVHCSAGA 1107
Query: 335 GRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTL 386
GRTGCFIA + G VDI V +LR R ++QT EQY F+H +
Sbjct: 1108 GRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAI 1159
Score = 120 bits (302), Expect = 2e-27
Identities = 84/267 (31%), Positives = 140/267 (52%), Gaps = 15/267 (5%)
Query: 135 QLEEEF--LKIPSNFVSPEDLDI---PGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYI 189
Q+++EF L I + V PED I P + K+R +LP + L E +YI
Sbjct: 1193 QIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDG-ESSNYI 1251
Query: 190 NANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPT 249
NA + + + ++ TQ P+PNTV+DFW +V+ S +VML ++ + + C+ YWP
Sbjct: 1252 NAALMDSHK-QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEM-DTAQFCMQYWPE 1309
Query: 250 EEE-TYGPFQIRI--QDMKECPEYTVRQLT--IQYQEERRSVKHILFSAWPDHQ-TPESA 303
+ YGP Q+ D+ E + + ++ + Q+ R V+H+ + WP ++ TP S
Sbjct: 1310 KTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSK 1369
Query: 304 GPLLRLVAEVEESPETA-AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIV 362
LL++V +E+ E G VVHC G GR+G F A C+ ++ + +D+ IV
Sbjct: 1370 RSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1429
Query: 363 CQLRLDRGGMIQTAEQYQFLHHTLALY 389
LR ++ M++T EQY+F++ Y
Sbjct: 1430 KTLRNNKSNMVETLEQYKFVYEVALEY 1456
>gi|208431815 protein tyrosine phosphatase, receptor type, K isoform a
[Homo sapiens]
Length = 1446
Score = 184 bits (468), Expect = 9e-47
Identities = 105/235 (44%), Positives = 135/235 (57%), Gaps = 10/235 (4%)
Query: 160 SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGY---DGKEKV--YIATQGPMPNT 214
+K+RY I+ SRV L + DYINANYI + DG ++ YIATQGP+ T
Sbjct: 913 AKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDIWLYRDGYQRPSHYIATQGPVHET 972
Query: 215 VSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVR 273
V DFW M+WQE+ + IVM+T L E G+ KC YWP + E YG F++ +M+ EY VR
Sbjct: 973 VYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVVR 1032
Query: 274 QLTIQYQ--EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCS 331
T++ + E R VK F+ WPDH P A LL + V+ S +A GPIVVHCS
Sbjct: 1033 TFTLERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPSA--GPIVVHCS 1090
Query: 332 AGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTL 386
AG GRTGC+I I + G VDI V LR R M+QT EQY F+H +
Sbjct: 1091 AGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAI 1145
Score = 103 bits (258), Expect = 2e-22
Identities = 83/269 (30%), Positives = 128/269 (47%), Gaps = 21/269 (7%)
Query: 136 LEEEFLKIPSNFVSP----EDLDI---PGHASKDRYKTILPNPQSRVCLGRAQSQEDGDY 188
L++EF + N V+P ED I P + K+R+ +LP + L E +Y
Sbjct: 1180 LKDEFQTL--NSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDG-ESSNY 1236
Query: 189 INANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWP 248
INA + Y + +I TQ P+PNTV DFW +V+ + IVML ++ + + C YWP
Sbjct: 1237 INAALMDSYR-QPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEV-DLSQGCPQYWP 1294
Query: 249 TEEET-YGPFQIRIQDMK-ECPE----YTVRQLTIQYQEERRSVKHILFSAWPDH-QTPE 301
E YGP Q+ +C + + LT + QE V+ + W H + P
Sbjct: 1295 EEGMLRYGPIQVECMSCSMDCDVINRIFRICNLT-RPQEGYLMVQQFQYLGWASHREVPG 1353
Query: 302 SAGPLLRLVAEVEESPETAAH-PGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILG 360
S L+L+ +VE+ E G ++HC G GR+G F A I + +K + VD+
Sbjct: 1354 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1413
Query: 361 IVCQLRLDRGGMIQTAEQYQFLHHTLALY 389
V LR + M++ EQY+F + Y
Sbjct: 1414 AVKTLRNSKPNMVEAPEQYRFCYDVALEY 1442
>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
isoform 4 precursor [Homo sapiens]
Length = 1505
Score = 184 bits (466), Expect = 2e-46
Identities = 103/257 (40%), Positives = 142/257 (55%), Gaps = 8/257 (3%)
Query: 135 QLEEEFLKI-PSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANY 193
+L +E+ I P + E ++ + K+RY ++ SRV L + DYINANY
Sbjct: 949 KLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANY 1008
Query: 194 IRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTE-E 251
+ GY + YIATQGP+P T DFW MVW++ + IVM+T+L E + KC YWP
Sbjct: 1009 VDGYRC-QNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGT 1067
Query: 252 ETYGPFQIRIQDMKECPEYTVRQLTIQYQ--EERRSVKHILFSAWPDHQTPESAGPLLRL 309
ETYG Q+ + D E + VR ++ E+R V+ F+AWPDH PE P L
Sbjct: 1068 ETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAF 1127
Query: 310 VAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR 369
+ V+ A GPIVVHCSAG+GRTGCFI +++K VD+ G V +R R
Sbjct: 1128 LRRVKTCNPPDA--GPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQR 1185
Query: 370 GGMIQTAEQYQFLHHTL 386
M+QT +QY F+H L
Sbjct: 1186 NYMVQTEDQYSFIHEAL 1202
Score = 181 bits (458), Expect = 1e-45
Identities = 97/251 (38%), Positives = 142/251 (56%), Gaps = 8/251 (3%)
Query: 145 SNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVY 204
S F+S ++P + K+R I+P +RVCL + E DYINA++I GY ++K Y
Sbjct: 1252 SRFISA---NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYR-QQKAY 1307
Query: 205 IATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEET-YGPFQIRIQ 262
IATQGP+ T DFW M+W+ +++VMLT+LRE G+EKC YWP E Y F +
Sbjct: 1308 IATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPM 1367
Query: 263 DMKECPEYTVRQ--LTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETA 320
P+Y +R+ +T + R+V+ F+ WP+ P+S + + +V ++ E
Sbjct: 1368 AEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQF 1427
Query: 321 AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQ 380
GPI VHCSAG+GRTG FI I ++++ G VDI V LR R M+QT ++YQ
Sbjct: 1428 GQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQ 1487
Query: 381 FLHHTLALYAG 391
F + Y G
Sbjct: 1488 FCYQAALEYLG 1498
>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
isoform 2 precursor [Homo sapiens]
Length = 1910
Score = 184 bits (466), Expect = 2e-46
Identities = 103/257 (40%), Positives = 142/257 (55%), Gaps = 8/257 (3%)
Query: 135 QLEEEFLKI-PSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANY 193
+L +E+ I P + E ++ + K+RY ++ SRV L + DYINANY
Sbjct: 1354 KLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANY 1413
Query: 194 IRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTE-E 251
+ GY + YIATQGP+P T DFW MVW++ + IVM+T+L E + KC YWP
Sbjct: 1414 VDGYRC-QNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGT 1472
Query: 252 ETYGPFQIRIQDMKECPEYTVRQLTIQYQ--EERRSVKHILFSAWPDHQTPESAGPLLRL 309
ETYG Q+ + D E + VR ++ E+R V+ F+AWPDH PE P L
Sbjct: 1473 ETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAF 1532
Query: 310 VAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR 369
+ V+ A GPIVVHCSAG+GRTGCFI +++K VD+ G V +R R
Sbjct: 1533 LRRVKTCNPPDA--GPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQR 1590
Query: 370 GGMIQTAEQYQFLHHTL 386
M+QT +QY F+H L
Sbjct: 1591 NYMVQTEDQYSFIHEAL 1607
Score = 181 bits (458), Expect = 1e-45
Identities = 97/251 (38%), Positives = 142/251 (56%), Gaps = 8/251 (3%)
Query: 145 SNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVY 204
S F+S ++P + K+R I+P +RVCL + E DYINA++I GY ++K Y
Sbjct: 1657 SRFISA---NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYR-QQKAY 1712
Query: 205 IATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEET-YGPFQIRIQ 262
IATQGP+ T DFW M+W+ +++VMLT+LRE G+EKC YWP E Y F +
Sbjct: 1713 IATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPM 1772
Query: 263 DMKECPEYTVRQ--LTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETA 320
P+Y +R+ +T + R+V+ F+ WP+ P+S + + +V ++ E
Sbjct: 1773 AEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQF 1832
Query: 321 AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQ 380
GPI VHCSAG+GRTG FI I ++++ G VDI V LR R M+QT ++YQ
Sbjct: 1833 GQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQ 1892
Query: 381 FLHHTLALYAG 391
F + Y G
Sbjct: 1893 FCYQAALEYLG 1903
>gi|104487295 protein tyrosine phosphatase, receptor type, sigma
isoform 3 precursor [Homo sapiens]
Length = 1501
Score = 184 bits (466), Expect = 2e-46
Identities = 103/257 (40%), Positives = 142/257 (55%), Gaps = 8/257 (3%)
Query: 135 QLEEEFLKI-PSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANY 193
+L +E+ I P + E ++ + K+RY ++ SRV L + DYINANY
Sbjct: 945 KLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANY 1004
Query: 194 IRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTE-E 251
+ GY + YIATQGP+P T DFW MVW++ + IVM+T+L E + KC YWP
Sbjct: 1005 VDGYRC-QNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGT 1063
Query: 252 ETYGPFQIRIQDMKECPEYTVRQLTIQYQ--EERRSVKHILFSAWPDHQTPESAGPLLRL 309
ETYG Q+ + D E + VR ++ E+R V+ F+AWPDH PE P L
Sbjct: 1064 ETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAF 1123
Query: 310 VAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR 369
+ V+ A GPIVVHCSAG+GRTGCFI +++K VD+ G V +R R
Sbjct: 1124 LRRVKTCNPPDA--GPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQR 1181
Query: 370 GGMIQTAEQYQFLHHTL 386
M+QT +QY F+H L
Sbjct: 1182 NYMVQTEDQYSFIHEAL 1198
Score = 181 bits (458), Expect = 1e-45
Identities = 97/251 (38%), Positives = 142/251 (56%), Gaps = 8/251 (3%)
Query: 145 SNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVY 204
S F+S ++P + K+R I+P +RVCL + E DYINA++I GY ++K Y
Sbjct: 1248 SRFISA---NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYR-QQKAY 1303
Query: 205 IATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEET-YGPFQIRIQ 262
IATQGP+ T DFW M+W+ +++VMLT+LRE G+EKC YWP E Y F +
Sbjct: 1304 IATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPM 1363
Query: 263 DMKECPEYTVRQ--LTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETA 320
P+Y +R+ +T + R+V+ F+ WP+ P+S + + +V ++ E
Sbjct: 1364 AEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQF 1423
Query: 321 AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQ 380
GPI VHCSAG+GRTG FI I ++++ G VDI V LR R M+QT ++YQ
Sbjct: 1424 GQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQ 1483
Query: 381 FLHHTLALYAG 391
F + Y G
Sbjct: 1484 FCYQAALEYLG 1494
>gi|18641364 protein tyrosine phosphatase, receptor type, C isoform
3 precursor [Homo sapiens]
Length = 1256
Score = 184 bits (466), Expect = 2e-46
Identities = 104/260 (40%), Positives = 146/260 (56%), Gaps = 12/260 (4%)
Query: 139 EFLKIPSNFVS--PEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRG 196
EF IP F ++ P + +K+RY ILP +RV L +YINA+YI G
Sbjct: 606 EFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDG 665
Query: 197 YDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPTEEE--- 252
+ K YIA QGP TV DFW M+W+++ ++IVM+T+ EG + KC YWP+ EE
Sbjct: 666 FKEPRK-YIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTR 724
Query: 253 TYGPFQIRIQDMKECPEYTVRQLTIQYQEER---RSVKHILFSAWPDHQTPESAGPLLRL 309
+G ++I K CP+Y +++L I ++E+ R V HI F++WPDH PE LL+L
Sbjct: 725 AFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKL 784
Query: 310 VAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR 369
V + GPIVVHCSAG+GRTG +I + L+A +VD+ G V +LR R
Sbjct: 785 RRRVNAFSNFFS--GPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQR 842
Query: 370 GGMIQTAEQYQFLHHTLALY 389
M+Q QY +H L Y
Sbjct: 843 CLMVQVEAQYILIHQALVEY 862
Score = 145 bits (366), Expect = 6e-35
Identities = 94/302 (31%), Positives = 155/302 (51%), Gaps = 34/302 (11%)
Query: 119 HPLTRWALQRQPPS-PKQLEEEFLKIPS--NFVSPEDLDIPGHASKDRYKTILPNPQSRV 175
HP +R PPS P LE EF ++PS ++ + + + SK+R ++P +RV
Sbjct: 876 HPYLHNMKKRDPPSEPSPLEAEFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRV 935
Query: 176 CLGR-------------------AQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVS 216
L + S+E YINA++I Y K +V IA QGP+ T+
Sbjct: 936 PLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSY-WKPEVMIAAQGPLKETIG 994
Query: 217 DFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQL 275
DFW+M++Q +V +IVMLT+L+ G +E C YW ++TYG ++ ++D + YT+R
Sbjct: 995 DFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGKQTYGDIEVDLKDTDKSSTYTLRVF 1054
Query: 276 TIQY--QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEES-PETAAHPG-------P 325
+++ +++ R+V ++ W Q P L+ ++ V++ P+ + G P
Sbjct: 1055 ELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTP 1114
Query: 326 IVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHT 385
+++HC G +TG F A + + VDI +V LR R GM+ T EQYQFL+
Sbjct: 1115 LLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDV 1174
Query: 386 LA 387
+A
Sbjct: 1175 IA 1176
>gi|18641347 protein tyrosine phosphatase, receptor type, C isoform
1 precursor [Homo sapiens]
Length = 1304
Score = 184 bits (466), Expect = 2e-46
Identities = 104/260 (40%), Positives = 146/260 (56%), Gaps = 12/260 (4%)
Query: 139 EFLKIPSNFVS--PEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRG 196
EF IP F ++ P + +K+RY ILP +RV L +YINA+YI G
Sbjct: 654 EFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDG 713
Query: 197 YDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPTEEE--- 252
+ K YIA QGP TV DFW M+W+++ ++IVM+T+ EG + KC YWP+ EE
Sbjct: 714 FKEPRK-YIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTR 772
Query: 253 TYGPFQIRIQDMKECPEYTVRQLTIQYQEER---RSVKHILFSAWPDHQTPESAGPLLRL 309
+G ++I K CP+Y +++L I ++E+ R V HI F++WPDH PE LL+L
Sbjct: 773 AFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKL 832
Query: 310 VAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR 369
V + GPIVVHCSAG+GRTG +I + L+A +VD+ G V +LR R
Sbjct: 833 RRRVNAFSNFFS--GPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQR 890
Query: 370 GGMIQTAEQYQFLHHTLALY 389
M+Q QY +H L Y
Sbjct: 891 CLMVQVEAQYILIHQALVEY 910
Score = 145 bits (366), Expect = 6e-35
Identities = 94/302 (31%), Positives = 155/302 (51%), Gaps = 34/302 (11%)
Query: 119 HPLTRWALQRQPPS-PKQLEEEFLKIPS--NFVSPEDLDIPGHASKDRYKTILPNPQSRV 175
HP +R PPS P LE EF ++PS ++ + + + SK+R ++P +RV
Sbjct: 924 HPYLHNMKKRDPPSEPSPLEAEFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRV 983
Query: 176 CLGR-------------------AQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVS 216
L + S+E YINA++I Y K +V IA QGP+ T+
Sbjct: 984 PLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSY-WKPEVMIAAQGPLKETIG 1042
Query: 217 DFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQL 275
DFW+M++Q +V +IVMLT+L+ G +E C YW ++TYG ++ ++D + YT+R
Sbjct: 1043 DFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGKQTYGDIEVDLKDTDKSSTYTLRVF 1102
Query: 276 TIQY--QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEES-PETAAHPG-------P 325
+++ +++ R+V ++ W Q P L+ ++ V++ P+ + G P
Sbjct: 1103 ELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTP 1162
Query: 326 IVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHT 385
+++HC G +TG F A + + VDI +V LR R GM+ T EQYQFL+
Sbjct: 1163 LLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDV 1222
Query: 386 LA 387
+A
Sbjct: 1223 IA 1224
>gi|18641362 protein tyrosine phosphatase, receptor type, C isoform
2 precursor [Homo sapiens]
Length = 1143
Score = 184 bits (466), Expect = 2e-46
Identities = 104/260 (40%), Positives = 146/260 (56%), Gaps = 12/260 (4%)
Query: 139 EFLKIPSNFVS--PEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRG 196
EF IP F ++ P + +K+RY ILP +RV L +YINA+YI G
Sbjct: 493 EFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDG 552
Query: 197 YDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPTEEE--- 252
+ K YIA QGP TV DFW M+W+++ ++IVM+T+ EG + KC YWP+ EE
Sbjct: 553 FKEPRK-YIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTR 611
Query: 253 TYGPFQIRIQDMKECPEYTVRQLTIQYQEER---RSVKHILFSAWPDHQTPESAGPLLRL 309
+G ++I K CP+Y +++L I ++E+ R V HI F++WPDH PE LL+L
Sbjct: 612 AFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKL 671
Query: 310 VAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR 369
V + GPIVVHCSAG+GRTG +I + L+A +VD+ G V +LR R
Sbjct: 672 RRRVNAFSNFFS--GPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQR 729
Query: 370 GGMIQTAEQYQFLHHTLALY 389
M+Q QY +H L Y
Sbjct: 730 CLMVQVEAQYILIHQALVEY 749
Score = 145 bits (366), Expect = 6e-35
Identities = 94/302 (31%), Positives = 155/302 (51%), Gaps = 34/302 (11%)
Query: 119 HPLTRWALQRQPPS-PKQLEEEFLKIPS--NFVSPEDLDIPGHASKDRYKTILPNPQSRV 175
HP +R PPS P LE EF ++PS ++ + + + SK+R ++P +RV
Sbjct: 763 HPYLHNMKKRDPPSEPSPLEAEFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRV 822
Query: 176 CLGR-------------------AQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVS 216
L + S+E YINA++I Y K +V IA QGP+ T+
Sbjct: 823 PLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSY-WKPEVMIAAQGPLKETIG 881
Query: 217 DFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQL 275
DFW+M++Q +V +IVMLT+L+ G +E C YW ++TYG ++ ++D + YT+R
Sbjct: 882 DFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGKQTYGDIEVDLKDTDKSSTYTLRVF 941
Query: 276 TIQY--QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEES-PETAAHPG-------P 325
+++ +++ R+V ++ W Q P L+ ++ V++ P+ + G P
Sbjct: 942 ELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTP 1001
Query: 326 IVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHT 385
+++HC G +TG F A + + VDI +V LR R GM+ T EQYQFL+
Sbjct: 1002 LLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDV 1061
Query: 386 LA 387
+A
Sbjct: 1062 IA 1063
>gi|104487002 protein tyrosine phosphatase, receptor type, D isoform 5
precursor [Homo sapiens]
Length = 1502
Score = 181 bits (460), Expect = 8e-46
Identities = 98/251 (39%), Positives = 142/251 (56%), Gaps = 8/251 (3%)
Query: 145 SNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVY 204
S F+S ++P + K+R I+P +RVCL + E DYINA++I GY ++K Y
Sbjct: 1249 SRFISA---NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYR-QQKAY 1304
Query: 205 IATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEET-YGPFQIRIQ 262
IATQGP+ T DFW M+W+ +++VMLT+LRE G+EKC YWP E Y F +
Sbjct: 1305 IATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPM 1364
Query: 263 DMKECPEYTVRQ--LTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETA 320
P+Y +R+ +T + R+V+ F+ WP+ P+S + + +V ++ E
Sbjct: 1365 AEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQF 1424
Query: 321 AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQ 380
GPI VHCSAG+GRTG FI I ++++ G VDI V LR R M+QT +QYQ
Sbjct: 1425 GQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQ 1484
Query: 381 FLHHTLALYAG 391
F + Y G
Sbjct: 1485 FSYRAALEYLG 1495
Score = 181 bits (459), Expect = 1e-45
Identities = 96/230 (41%), Positives = 130/230 (56%), Gaps = 7/230 (3%)
Query: 161 KDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWE 220
K+RY ++ SRV L + DY+NANYI GY K+ YIATQG +P T DFW
Sbjct: 973 KNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYR-KQNAYIATQGSLPETFGDFWR 1031
Query: 221 MVWQEEVSLIVMLTQLRE-GKEKCVHYWPTE-EETYGPFQIRIQDMKECPEYTVRQLTIQ 278
M+W++ + +VM+T+L E + KC YWP+ ET+G Q+ + D E Y VR +
Sbjct: 1032 MIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALY 1091
Query: 279 YQ--EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGR 336
E+R V+ F+AWPDH PE P L + V+ A GP+VVHCSAG+GR
Sbjct: 1092 KNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDA--GPMVVHCSAGVGR 1149
Query: 337 TGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTL 386
TGCFI +++K VDI G V +R R M+QT +QY F+H L
Sbjct: 1150 TGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1199
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 181 bits (460), Expect = 8e-46
Identities = 98/251 (39%), Positives = 142/251 (56%), Gaps = 8/251 (3%)
Query: 145 SNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVY 204
S F+S ++P + K+R I+P +RVCL + E DYINA++I GY ++K Y
Sbjct: 1659 SRFISA---NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYR-QQKAY 1714
Query: 205 IATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEET-YGPFQIRIQ 262
IATQGP+ T DFW M+W+ +++VMLT+LRE G+EKC YWP E Y F +
Sbjct: 1715 IATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPM 1774
Query: 263 DMKECPEYTVRQ--LTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETA 320
P+Y +R+ +T + R+V+ F+ WP+ P+S + + +V ++ E
Sbjct: 1775 AEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQF 1834
Query: 321 AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQ 380
GPI VHCSAG+GRTG FI I ++++ G VDI V LR R M+QT +QYQ
Sbjct: 1835 GQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQ 1894
Query: 381 FLHHTLALYAG 391
F + Y G
Sbjct: 1895 FSYRAALEYLG 1905
Score = 181 bits (459), Expect = 1e-45
Identities = 96/230 (41%), Positives = 130/230 (56%), Gaps = 7/230 (3%)
Query: 161 KDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWE 220
K+RY ++ SRV L + DY+NANYI GY K+ YIATQG +P T DFW
Sbjct: 1383 KNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYR-KQNAYIATQGSLPETFGDFWR 1441
Query: 221 MVWQEEVSLIVMLTQLRE-GKEKCVHYWPTE-EETYGPFQIRIQDMKECPEYTVRQLTIQ 278
M+W++ + +VM+T+L E + KC YWP+ ET+G Q+ + D E Y VR +
Sbjct: 1442 MIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALY 1501
Query: 279 YQ--EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGR 336
E+R V+ F+AWPDH PE P L + V+ A GP+VVHCSAG+GR
Sbjct: 1502 KNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDA--GPMVVHCSAGVGR 1559
Query: 337 TGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTL 386
TGCFI +++K VDI G V +R R M+QT +QY F+H L
Sbjct: 1560 TGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1609
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,328,064
Number of Sequences: 37866
Number of extensions: 935571
Number of successful extensions: 3188
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 103
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2593
Number of HSP's gapped (non-prelim): 152
length of query: 399
length of database: 18,247,518
effective HSP length: 104
effective length of query: 295
effective length of database: 14,309,454
effective search space: 4221288930
effective search space used: 4221288930
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.