Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 18375658

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18375658 protein tyrosine phosphatase, non-receptor type 7
isoform 1 [Homo sapiens]
         (360 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18375660 protein tyrosine phosphatase, non-receptor type 7 is...   742   0.0  
gi|18375658 protein tyrosine phosphatase, non-receptor type 7 is...   742   0.0  
gi|4506325 protein tyrosine phosphatase, receptor type, R isofor...   382   e-106
gi|19743917 protein tyrosine phosphatase, receptor type, R isofo...   382   e-106
gi|90652861 protein-tyrosine-phosphatase non-receptor 5 isoform ...   332   3e-91
gi|90652859 protein-tyrosine-phosphatase non-receptor 5 isoform ...   332   3e-91
gi|90652853 protein-tyrosine-phosphatase non-receptor 5 isoform ...   332   3e-91
gi|13677222 receptor-type protein tyrosine phosphatase O isoform...   191   7e-49
gi|13677220 receptor-type protein tyrosine phosphatase O isoform...   191   7e-49
gi|13677218 receptor-type protein tyrosine phosphatase O isoform...   191   7e-49
gi|13677216 receptor-type protein tyrosine phosphatase O isoform...   191   7e-49
gi|13677214 receptor-type protein tyrosine phosphatase O isoform...   191   7e-49
gi|4506323 receptor-type protein tyrosine phosphatase O isoform ...   191   7e-49
gi|18860902 protein tyrosine phosphatase, receptor type, K isofo...   191   1e-48
gi|157952215 protein tyrosine phosphatase, receptor type, B isof...   188   7e-48
gi|157952213 protein tyrosine phosphatase, receptor type, B isof...   188   7e-48
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ...   187   2e-47
gi|109633041 protein tyrosine phosphatase, receptor type, F isof...   186   4e-47
gi|109633039 protein tyrosine phosphatase, receptor type, F isof...   186   4e-47
gi|148539860 protein tyrosine phosphatase, receptor type, T isof...   185   5e-47
gi|148539858 protein tyrosine phosphatase, receptor type, T isof...   185   5e-47
gi|208431815 protein tyrosine phosphatase, receptor type, K isof...   184   8e-47
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ...   184   1e-46
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ...   184   1e-46
gi|104487295 protein tyrosine phosphatase, receptor type, sigma ...   184   1e-46
gi|18641364 protein tyrosine phosphatase, receptor type, C isofo...   184   1e-46
gi|18641347 protein tyrosine phosphatase, receptor type, C isofo...   184   1e-46
gi|18641362 protein tyrosine phosphatase, receptor type, C isofo...   184   1e-46
gi|104487002 protein tyrosine phosphatase, receptor type, D isof...   181   7e-46
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor...   181   7e-46

>gi|18375660 protein tyrosine phosphatase, non-receptor type 7
           isoform 2 [Homo sapiens]
          Length = 399

 Score =  742 bits (1915), Expect = 0.0
 Identities = 360/360 (100%), Positives = 360/360 (100%)

Query: 1   MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP 60
           MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
Sbjct: 40  MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP 99

Query: 61  ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA 120
           ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
Sbjct: 100 ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA 159

Query: 121 SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW 180
           SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
Sbjct: 160 SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW 219

Query: 181 EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY 240
           EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
Sbjct: 220 EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY 279

Query: 241 QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC 300
           QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
Sbjct: 280 QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC 339

Query: 301 FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP 360
           FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
Sbjct: 340 FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP 399


>gi|18375658 protein tyrosine phosphatase, non-receptor type 7
           isoform 1 [Homo sapiens]
          Length = 360

 Score =  742 bits (1915), Expect = 0.0
 Identities = 360/360 (100%), Positives = 360/360 (100%)

Query: 1   MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP 60
           MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
Sbjct: 1   MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP 60

Query: 61  ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA 120
           ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
Sbjct: 61  ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA 120

Query: 121 SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW 180
           SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
Sbjct: 121 SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW 180

Query: 181 EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY 240
           EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
Sbjct: 181 EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY 240

Query: 241 QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC 300
           QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
Sbjct: 241 QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC 300

Query: 301 FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP 360
           FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
Sbjct: 301 FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP 360


>gi|4506325 protein tyrosine phosphatase, receptor type, R isoform 1
           precursor [Homo sapiens]
          Length = 657

 Score =  382 bits (982), Expect = e-106
 Identities = 192/353 (54%), Positives = 246/353 (69%), Gaps = 7/353 (1%)

Query: 8   RSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTP 67
           + R  P   +  A    P P K    K + LQERRGSNV+L LD+ SLG +EP  S+ TP
Sbjct: 306 QGRGAPEIRATTATSVCPSPFKM---KPIGLQERRGSNVSLTLDMSSLGNIEPFVSIPTP 362

Query: 68  RE-VTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYK 126
           RE V + +L++A   LTR  L+    S   L+ EF++IP NFV P+++DIP H +K+RYK
Sbjct: 363 REKVAMEYLQSASRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYK 422

Query: 127 TILPNPQSRVCLGRAQSQEDG--DYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVW 184
           TILPNP SRVCL R ++  D    YINANYIRGY GKEK +IATQGPM NTV DFW+MVW
Sbjct: 423 TILPNPLSRVCL-RPKNVTDSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVW 481

Query: 185 QEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEER 244
           QE+  +IVM+T+L+E  EKCV YWP +   YG  ++ +  + EC  YT+R L ++     
Sbjct: 482 QEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVISVNECDNYTIRNLVLKQGSHT 541

Query: 245 RSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIAT 304
           + VKH  +++WPDH+TP+SA PLL+L+ +VEE    +   GP+VVHCSAGIGRTGCFIAT
Sbjct: 542 QHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIAT 601

Query: 305 RIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEE 357
            IGCQQLK  G VD L IVCQLR+DRGGM+QT+EQY+F+HH L LY  +L  E
Sbjct: 602 SIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLYESRLSAE 654


>gi|19743917 protein tyrosine phosphatase, receptor type, R isoform
           2 [Homo sapiens]
          Length = 412

 Score =  382 bits (982), Expect = e-106
 Identities = 192/353 (54%), Positives = 246/353 (69%), Gaps = 7/353 (1%)

Query: 8   RSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTP 67
           + R  P   +  A    P P K    K + LQERRGSNV+L LD+ SLG +EP  S+ TP
Sbjct: 61  QGRGAPEIRATTATSVCPSPFKM---KPIGLQERRGSNVSLTLDMSSLGNIEPFVSIPTP 117

Query: 68  RE-VTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYK 126
           RE V + +L++A   LTR  L+    S   L+ EF++IP NFV P+++DIP H +K+RYK
Sbjct: 118 REKVAMEYLQSASRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYK 177

Query: 127 TILPNPQSRVCLGRAQSQEDG--DYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVW 184
           TILPNP SRVCL R ++  D    YINANYIRGY GKEK +IATQGPM NTV DFW+MVW
Sbjct: 178 TILPNPLSRVCL-RPKNVTDSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVW 236

Query: 185 QEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEER 244
           QE+  +IVM+T+L+E  EKCV YWP +   YG  ++ +  + EC  YT+R L ++     
Sbjct: 237 QEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVISVNECDNYTIRNLVLKQGSHT 296

Query: 245 RSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIAT 304
           + VKH  +++WPDH+TP+SA PLL+L+ +VEE    +   GP+VVHCSAGIGRTGCFIAT
Sbjct: 297 QHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIAT 356

Query: 305 RIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEE 357
            IGCQQLK  G VD L IVCQLR+DRGGM+QT+EQY+F+HH L LY  +L  E
Sbjct: 357 SIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLYESRLSAE 409


>gi|90652861 protein-tyrosine-phosphatase non-receptor 5 isoform b
           [Homo sapiens]
          Length = 533

 Score =  332 bits (851), Expect = 3e-91
 Identities = 174/338 (51%), Positives = 220/338 (65%), Gaps = 7/338 (2%)

Query: 27  PEKTPAK---KHVRLQERRGSNVALMLDVRSLGAVEP-ICSVNTPREVTLH-FLRTAGHP 81
           PE  P     K + LQERRGSNV+L LD+ + G  E     + +PRE +   +L +A   
Sbjct: 193 PEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRV 252

Query: 82  LTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRA 141
           L    L  +   P  L+ EF +IP NFV P++ DIPG   K+RYKTILPNP SRVCL   
Sbjct: 253 LQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSP 312

Query: 142 QSQED-GDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG 200
              +    YINANYIRGY G+EKVYIATQGP+ +TV+DFW MVWQE   +IVM+T + E 
Sbjct: 313 DPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEM 372

Query: 201 KEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQT 260
            EKC  YWP E+  Y   +I +Q +    +Y +R ++++   E R +KH  F++WPD +T
Sbjct: 373 NEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKT 432

Query: 261 PESAGPLLRLVAEVEE-SPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDI 319
           P+ A PLL LV EVEE + +   H  PI+VHCSAGIGRTGCFIAT I CQQL+  G VDI
Sbjct: 433 PDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDI 492

Query: 320 LGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEE 357
           L   CQLR DRGGMIQT EQYQF+HH ++LY  QL  +
Sbjct: 493 LKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQ 530


>gi|90652859 protein-tyrosine-phosphatase non-receptor 5 isoform a
           [Homo sapiens]
          Length = 565

 Score =  332 bits (851), Expect = 3e-91
 Identities = 174/338 (51%), Positives = 220/338 (65%), Gaps = 7/338 (2%)

Query: 27  PEKTPAK---KHVRLQERRGSNVALMLDVRSLGAVEP-ICSVNTPREVTLH-FLRTAGHP 81
           PE  P     K + LQERRGSNV+L LD+ + G  E     + +PRE +   +L +A   
Sbjct: 225 PEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRV 284

Query: 82  LTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRA 141
           L    L  +   P  L+ EF +IP NFV P++ DIPG   K+RYKTILPNP SRVCL   
Sbjct: 285 LQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSP 344

Query: 142 QSQED-GDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG 200
              +    YINANYIRGY G+EKVYIATQGP+ +TV+DFW MVWQE   +IVM+T + E 
Sbjct: 345 DPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEM 404

Query: 201 KEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQT 260
            EKC  YWP E+  Y   +I +Q +    +Y +R ++++   E R +KH  F++WPD +T
Sbjct: 405 NEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKT 464

Query: 261 PESAGPLLRLVAEVEE-SPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDI 319
           P+ A PLL LV EVEE + +   H  PI+VHCSAGIGRTGCFIAT I CQQL+  G VDI
Sbjct: 465 PDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDI 524

Query: 320 LGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEE 357
           L   CQLR DRGGMIQT EQYQF+HH ++LY  QL  +
Sbjct: 525 LKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQ 562


>gi|90652853 protein-tyrosine-phosphatase non-receptor 5 isoform a
           [Homo sapiens]
          Length = 565

 Score =  332 bits (851), Expect = 3e-91
 Identities = 174/338 (51%), Positives = 220/338 (65%), Gaps = 7/338 (2%)

Query: 27  PEKTPAK---KHVRLQERRGSNVALMLDVRSLGAVEP-ICSVNTPREVTLH-FLRTAGHP 81
           PE  P     K + LQERRGSNV+L LD+ + G  E     + +PRE +   +L +A   
Sbjct: 225 PEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRV 284

Query: 82  LTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRA 141
           L    L  +   P  L+ EF +IP NFV P++ DIPG   K+RYKTILPNP SRVCL   
Sbjct: 285 LQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSP 344

Query: 142 QSQED-GDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG 200
              +    YINANYIRGY G+EKVYIATQGP+ +TV+DFW MVWQE   +IVM+T + E 
Sbjct: 345 DPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEM 404

Query: 201 KEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQT 260
            EKC  YWP E+  Y   +I +Q +    +Y +R ++++   E R +KH  F++WPD +T
Sbjct: 405 NEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKT 464

Query: 261 PESAGPLLRLVAEVEE-SPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDI 319
           P+ A PLL LV EVEE + +   H  PI+VHCSAGIGRTGCFIAT I CQQL+  G VDI
Sbjct: 465 PDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDI 524

Query: 320 LGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEE 357
           L   CQLR DRGGMIQT EQYQF+HH ++LY  QL  +
Sbjct: 525 LKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQ 562


>gi|13677222 receptor-type protein tyrosine phosphatase O isoform c
           precursor [Homo sapiens]
          Length = 405

 Score =  191 bits (486), Expect = 7e-49
 Identities = 108/258 (41%), Positives = 151/258 (58%), Gaps = 8/258 (3%)

Query: 97  LEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIR 156
           L+ E LK+    +     D+P +  K+RY  ILP   SRV L     +E  DYINANYI 
Sbjct: 129 LQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIP 188

Query: 157 GYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKE-KCVHYWPTEEE-- 213
           GY+  ++ YIATQGP+P T +DFW+MV Q++  +IVMLTQ  E +  KC HYWP  EE  
Sbjct: 189 GYNSPQE-YIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI 247

Query: 214 TYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTP--ESAGPLLRLV 271
            YG   + +   +E  ++  R   I Y +E + V H  ++AWPDH  P   +A  +L+ V
Sbjct: 248 AYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFV 307

Query: 272 AEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRG 331
             V +  +     GP+++HCSAG+GRTG FIA     Q ++    VDILG+V ++R  R 
Sbjct: 308 HMVRQ--QATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRM 365

Query: 332 GMIQTAEQYQFLHHTLAL 349
            M+QT EQY F+H  + L
Sbjct: 366 SMVQTEEQYIFIHQCVQL 383


>gi|13677220 receptor-type protein tyrosine phosphatase O isoform d
           precursor [Homo sapiens]
          Length = 377

 Score =  191 bits (486), Expect = 7e-49
 Identities = 108/258 (41%), Positives = 151/258 (58%), Gaps = 8/258 (3%)

Query: 97  LEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIR 156
           L+ E LK+    +     D+P +  K+RY  ILP   SRV L     +E  DYINANYI 
Sbjct: 101 LQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIP 160

Query: 157 GYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKE-KCVHYWPTEEE-- 213
           GY+  ++ YIATQGP+P T +DFW+MV Q++  +IVMLTQ  E +  KC HYWP  EE  
Sbjct: 161 GYNSPQE-YIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI 219

Query: 214 TYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTP--ESAGPLLRLV 271
            YG   + +   +E  ++  R   I Y +E + V H  ++AWPDH  P   +A  +L+ V
Sbjct: 220 AYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFV 279

Query: 272 AEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRG 331
             V +  +     GP+++HCSAG+GRTG FIA     Q ++    VDILG+V ++R  R 
Sbjct: 280 HMVRQ--QATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRM 337

Query: 332 GMIQTAEQYQFLHHTLAL 349
            M+QT EQY F+H  + L
Sbjct: 338 SMVQTEEQYIFIHQCVQL 355


>gi|13677218 receptor-type protein tyrosine phosphatase O isoform c
           precursor [Homo sapiens]
          Length = 405

 Score =  191 bits (486), Expect = 7e-49
 Identities = 108/258 (41%), Positives = 151/258 (58%), Gaps = 8/258 (3%)

Query: 97  LEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIR 156
           L+ E LK+    +     D+P +  K+RY  ILP   SRV L     +E  DYINANYI 
Sbjct: 129 LQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIP 188

Query: 157 GYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKE-KCVHYWPTEEE-- 213
           GY+  ++ YIATQGP+P T +DFW+MV Q++  +IVMLTQ  E +  KC HYWP  EE  
Sbjct: 189 GYNSPQE-YIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI 247

Query: 214 TYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTP--ESAGPLLRLV 271
            YG   + +   +E  ++  R   I Y +E + V H  ++AWPDH  P   +A  +L+ V
Sbjct: 248 AYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFV 307

Query: 272 AEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRG 331
             V +  +     GP+++HCSAG+GRTG FIA     Q ++    VDILG+V ++R  R 
Sbjct: 308 HMVRQ--QATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRM 365

Query: 332 GMIQTAEQYQFLHHTLAL 349
            M+QT EQY F+H  + L
Sbjct: 366 SMVQTEEQYIFIHQCVQL 383


>gi|13677216 receptor-type protein tyrosine phosphatase O isoform d
           precursor [Homo sapiens]
          Length = 377

 Score =  191 bits (486), Expect = 7e-49
 Identities = 108/258 (41%), Positives = 151/258 (58%), Gaps = 8/258 (3%)

Query: 97  LEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIR 156
           L+ E LK+    +     D+P +  K+RY  ILP   SRV L     +E  DYINANYI 
Sbjct: 101 LQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIP 160

Query: 157 GYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKE-KCVHYWPTEEE-- 213
           GY+  ++ YIATQGP+P T +DFW+MV Q++  +IVMLTQ  E +  KC HYWP  EE  
Sbjct: 161 GYNSPQE-YIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI 219

Query: 214 TYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTP--ESAGPLLRLV 271
            YG   + +   +E  ++  R   I Y +E + V H  ++AWPDH  P   +A  +L+ V
Sbjct: 220 AYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFV 279

Query: 272 AEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRG 331
             V +  +     GP+++HCSAG+GRTG FIA     Q ++    VDILG+V ++R  R 
Sbjct: 280 HMVRQ--QATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRM 337

Query: 332 GMIQTAEQYQFLHHTLAL 349
            M+QT EQY F+H  + L
Sbjct: 338 SMVQTEEQYIFIHQCVQL 355


>gi|13677214 receptor-type protein tyrosine phosphatase O isoform a
            precursor [Homo sapiens]
          Length = 1216

 Score =  191 bits (486), Expect = 7e-49
 Identities = 108/258 (41%), Positives = 151/258 (58%), Gaps = 8/258 (3%)

Query: 97   LEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIR 156
            L+ E LK+    +     D+P +  K+RY  ILP   SRV L     +E  DYINANYI 
Sbjct: 940  LQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIP 999

Query: 157  GYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKE-KCVHYWPTEEE-- 213
            GY+  ++ YIATQGP+P T +DFW+MV Q++  +IVMLTQ  E +  KC HYWP  EE  
Sbjct: 1000 GYNSPQE-YIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI 1058

Query: 214  TYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTP--ESAGPLLRLV 271
             YG   + +   +E  ++  R   I Y +E + V H  ++AWPDH  P   +A  +L+ V
Sbjct: 1059 AYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFV 1118

Query: 272  AEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRG 331
              V +  +     GP+++HCSAG+GRTG FIA     Q ++    VDILG+V ++R  R 
Sbjct: 1119 HMVRQ--QATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRM 1176

Query: 332  GMIQTAEQYQFLHHTLAL 349
             M+QT EQY F+H  + L
Sbjct: 1177 SMVQTEEQYIFIHQCVQL 1194


>gi|4506323 receptor-type protein tyrosine phosphatase O isoform b
            precursor [Homo sapiens]
          Length = 1188

 Score =  191 bits (486), Expect = 7e-49
 Identities = 108/258 (41%), Positives = 151/258 (58%), Gaps = 8/258 (3%)

Query: 97   LEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIR 156
            L+ E LK+    +     D+P +  K+RY  ILP   SRV L     +E  DYINANYI 
Sbjct: 912  LQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIP 971

Query: 157  GYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKE-KCVHYWPTEEE-- 213
            GY+  ++ YIATQGP+P T +DFW+MV Q++  +IVMLTQ  E +  KC HYWP  EE  
Sbjct: 972  GYNSPQE-YIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI 1030

Query: 214  TYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTP--ESAGPLLRLV 271
             YG   + +   +E  ++  R   I Y +E + V H  ++AWPDH  P   +A  +L+ V
Sbjct: 1031 AYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFV 1090

Query: 272  AEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRG 331
              V +  +     GP+++HCSAG+GRTG FIA     Q ++    VDILG+V ++R  R 
Sbjct: 1091 HMVRQ--QATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRM 1148

Query: 332  GMIQTAEQYQFLHHTLAL 349
             M+QT EQY F+H  + L
Sbjct: 1149 SMVQTEEQYIFIHQCVQL 1166


>gi|18860902 protein tyrosine phosphatase, receptor type, K isoform b
            [Homo sapiens]
          Length = 1440

 Score =  191 bits (484), Expect = 1e-48
 Identities = 105/230 (45%), Positives = 133/230 (57%), Gaps = 6/230 (2%)

Query: 121  SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW 180
            +K+RY  I+    SRV L   +     DYINANYI GY  +   YIATQGP+  TV DFW
Sbjct: 913  AKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQ-RPSHYIATQGPVHETVYDFW 971

Query: 181  EMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQ 239
             M+WQE+ + IVM+T L E G+ KC  YWP + E YG F++   +M+   EY VR  T++
Sbjct: 972  RMIWQEQSACIVMVTNLVEVGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVVRTFTLE 1031

Query: 240  YQ--EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGR 297
             +   E R VK   F+ WPDH  P  A  LL  +  V+ S   +A  GPIVVHCSAG GR
Sbjct: 1032 RRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPSA--GPIVVHCSAGAGR 1089

Query: 298  TGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTL 347
            TGC+I   I     +  G VDI   V  LR  R  M+QT EQY F+H  +
Sbjct: 1090 TGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAI 1139



 Score =  103 bits (258), Expect = 2e-22
 Identities = 83/269 (30%), Positives = 128/269 (47%), Gaps = 21/269 (7%)

Query: 97   LEEEFLKIPSNFVSP----EDLDI---PGHASKDRYKTILPNPQSRVCLGRAQSQEDGDY 149
            L++EF  +  N V+P    ED  I   P +  K+R+  +LP  +    L      E  +Y
Sbjct: 1174 LKDEFQTL--NSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDG-ESSNY 1230

Query: 150  INANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWP 209
            INA  +  Y  +   +I TQ P+PNTV DFW +V+    + IVML ++ +  + C  YWP
Sbjct: 1231 INAALMDSYR-QPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEV-DLSQGCPQYWP 1288

Query: 210  TEEET-YGPFQIRIQDMK-ECPE----YTVRQLTIQYQEERRSVKHILFSAWPDH-QTPE 262
             E    YGP Q+       +C      + +  LT + QE    V+   +  W  H + P 
Sbjct: 1289 EEGMLRYGPIQVECMSCSMDCDVINRIFRICNLT-RPQEGYLMVQQFQYLGWASHREVPG 1347

Query: 263  SAGPLLRLVAEVEESPETAAH-PGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILG 321
            S    L+L+ +VE+  E      G  ++HC  G GR+G F A  I  + +K +  VD+  
Sbjct: 1348 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1407

Query: 322  IVCQLRLDRGGMIQTAEQYQFLHHTLALY 350
             V  LR  +  M++  EQY+F +     Y
Sbjct: 1408 AVKTLRNSKPNMVEAPEQYRFCYDVALEY 1436


>gi|157952215 protein tyrosine phosphatase, receptor type, B isoform a
            [Homo sapiens]
          Length = 2215

 Score =  188 bits (477), Expect = 7e-48
 Identities = 99/235 (42%), Positives = 141/235 (60%), Gaps = 7/235 (2%)

Query: 116  IPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNT 175
            +P +  K+RY  ILP   +RV L         DYINA+YI G + + + YI TQGP+P T
Sbjct: 1942 LPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRRE-YIVTQGPLPGT 2000

Query: 176  VSDFWEMVWQEEVSLIVMLTQ-LREGKEKCVHYWPTEEET--YGPFQIRIQDMKECPEYT 232
              DFW+MVW++ V  IVM+TQ + +G+ KC HYWP ++++  YG   +++      PE+T
Sbjct: 2001 KDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWT 2060

Query: 233  VRQLTIQYQEE---RRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVV 289
            +R+  I  +E+    R ++H  ++ WPDH  PE+   L++ V  V +    +   GP VV
Sbjct: 2061 IREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVV 2120

Query: 290  HCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLH 344
            HCSAG+GRTG FIA     QQL ++  VDI G V  LRL R  M+QT  QY +LH
Sbjct: 2121 HCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLH 2175


>gi|157952213 protein tyrosine phosphatase, receptor type, B isoform b
            precursor [Homo sapiens]
          Length = 1997

 Score =  188 bits (477), Expect = 7e-48
 Identities = 99/235 (42%), Positives = 141/235 (60%), Gaps = 7/235 (2%)

Query: 116  IPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNT 175
            +P +  K+RY  ILP   +RV L         DYINA+YI G + + + YI TQGP+P T
Sbjct: 1724 LPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRRE-YIVTQGPLPGT 1782

Query: 176  VSDFWEMVWQEEVSLIVMLTQ-LREGKEKCVHYWPTEEET--YGPFQIRIQDMKECPEYT 232
              DFW+MVW++ V  IVM+TQ + +G+ KC HYWP ++++  YG   +++      PE+T
Sbjct: 1783 KDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWT 1842

Query: 233  VRQLTIQYQEE---RRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVV 289
            +R+  I  +E+    R ++H  ++ WPDH  PE+   L++ V  V +    +   GP VV
Sbjct: 1843 IREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVV 1902

Query: 290  HCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLH 344
            HCSAG+GRTG FIA     QQL ++  VDI G V  LRL R  M+QT  QY +LH
Sbjct: 1903 HCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLH 1957


>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
            isoform 1 precursor [Homo sapiens]
          Length = 1948

 Score =  187 bits (474), Expect = 2e-47
 Identities = 112/310 (36%), Positives = 160/310 (51%), Gaps = 15/310 (4%)

Query: 50   LDVRSLGAVEPICSVNTP-REVTLHFLRTAGHP------LTRWALQRQPPSPKQLEEEFL 102
            +++R +    P   + +P RE   HF     HP      +     + +     +L +E+ 
Sbjct: 1339 VEMRRINFQTPDSGLRSPLREPGFHFESMLSHPPIPIADMAEHTERLKANDSLKLSQEYE 1398

Query: 103  KI-PSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGK 161
             I P    + E  ++  +  K+RY  ++    SRV L   +     DYINANY+ GY   
Sbjct: 1399 SIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRC- 1457

Query: 162  EKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTE-EETYGPFQ 219
            +  YIATQGP+P T  DFW MVW++  + IVM+T+L E  + KC  YWP    ETYG  Q
Sbjct: 1458 QNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQ 1517

Query: 220  IRIQDMKECPEYTVRQLTIQYQ--EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEES 277
            + + D  E   + VR  ++      E+R V+   F+AWPDH  PE   P L  +  V+  
Sbjct: 1518 VTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTC 1577

Query: 278  PETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTA 337
                A  GPIVVHCSAG+GRTGCFI      +++K    VD+ G V  +R  R  M+QT 
Sbjct: 1578 NPPDA--GPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTE 1635

Query: 338  EQYQFLHHTL 347
            +QY F+H  L
Sbjct: 1636 DQYSFIHEAL 1645



 Score =  181 bits (458), Expect = 1e-45
 Identities = 97/251 (38%), Positives = 142/251 (56%), Gaps = 8/251 (3%)

Query: 106  SNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVY 165
            S F+S    ++P +  K+R   I+P   +RVCL   +  E  DYINA++I GY  ++K Y
Sbjct: 1695 SRFISA---NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYR-QQKAY 1750

Query: 166  IATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEET-YGPFQIRIQ 223
            IATQGP+  T  DFW M+W+   +++VMLT+LRE G+EKC  YWP E    Y  F +   
Sbjct: 1751 IATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPM 1810

Query: 224  DMKECPEYTVRQ--LTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETA 281
                 P+Y +R+  +T     + R+V+   F+ WP+   P+S    +  + +V ++ E  
Sbjct: 1811 AEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQF 1870

Query: 282  AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQ 341
               GPI VHCSAG+GRTG FI   I  ++++  G VDI   V  LR  R  M+QT ++YQ
Sbjct: 1871 GQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQ 1930

Query: 342  FLHHTLALYAG 352
            F +     Y G
Sbjct: 1931 FCYQAALEYLG 1941


>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
            precursor [Homo sapiens]
          Length = 1907

 Score =  186 bits (471), Expect = 4e-47
 Identities = 100/240 (41%), Positives = 135/240 (56%), Gaps = 7/240 (2%)

Query: 112  EDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGP 171
            E+ ++  +  K+RY  ++    SRV L         DYINANYI GY  K+  YIATQGP
Sbjct: 1368 ENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYR-KQNAYIATQGP 1426

Query: 172  MPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTE-EETYGPFQIRIQDMKECP 229
            +P T+ DFW MVW++  + +VM+T+L E  + KC  YWP    ET G  Q+ + D  E  
Sbjct: 1427 LPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELA 1486

Query: 230  EYTVRQLTIQYQ--EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPI 287
             YTVR   +      E+R ++   F AWPDH  PE   P+L  +  V+      A  GP+
Sbjct: 1487 TYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDA--GPM 1544

Query: 288  VVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTL 347
            VVHCSAG+GRTGCFI      +++K    VDI G V  +R  R  M+QT +QY F+H  L
Sbjct: 1545 VVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEAL 1604



 Score =  174 bits (442), Expect = 8e-44
 Identities = 93/251 (37%), Positives = 141/251 (56%), Gaps = 8/251 (3%)

Query: 106  SNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVY 165
            S F+S    ++P +  K+R   I+P   +RVCL   +  E  DYINA+++ GY  ++K Y
Sbjct: 1654 SRFISA---NLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYR-QQKAY 1709

Query: 166  IATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEET-YGPFQIRIQ 223
            IATQGP+  +  DFW M+W+   ++IVMLT+LRE G+EKC  YWP E    Y  F +   
Sbjct: 1710 IATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPM 1769

Query: 224  DMKECPEYTVRQ--LTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETA 281
                 P+Y +R+  +T     + R+++   F+ WP+   P++    +  + +V ++ E  
Sbjct: 1770 AEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQF 1829

Query: 282  AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQ 341
               GPI VHCSAG+GRTG FI   I  ++++  G VD+   V  LR  R  M+QT +QYQ
Sbjct: 1830 GQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQ 1889

Query: 342  FLHHTLALYAG 352
              +     Y G
Sbjct: 1890 LCYRAALEYLG 1900


>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
            precursor [Homo sapiens]
          Length = 1898

 Score =  186 bits (471), Expect = 4e-47
 Identities = 100/240 (41%), Positives = 135/240 (56%), Gaps = 7/240 (2%)

Query: 112  EDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGP 171
            E+ ++  +  K+RY  ++    SRV L         DYINANYI GY  K+  YIATQGP
Sbjct: 1359 ENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYR-KQNAYIATQGP 1417

Query: 172  MPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTE-EETYGPFQIRIQDMKECP 229
            +P T+ DFW MVW++  + +VM+T+L E  + KC  YWP    ET G  Q+ + D  E  
Sbjct: 1418 LPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELA 1477

Query: 230  EYTVRQLTIQYQ--EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPI 287
             YTVR   +      E+R ++   F AWPDH  PE   P+L  +  V+      A  GP+
Sbjct: 1478 TYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDA--GPM 1535

Query: 288  VVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTL 347
            VVHCSAG+GRTGCFI      +++K    VDI G V  +R  R  M+QT +QY F+H  L
Sbjct: 1536 VVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEAL 1595



 Score =  174 bits (442), Expect = 8e-44
 Identities = 93/251 (37%), Positives = 141/251 (56%), Gaps = 8/251 (3%)

Query: 106  SNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVY 165
            S F+S    ++P +  K+R   I+P   +RVCL   +  E  DYINA+++ GY  ++K Y
Sbjct: 1645 SRFISA---NLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYR-QQKAY 1700

Query: 166  IATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEET-YGPFQIRIQ 223
            IATQGP+  +  DFW M+W+   ++IVMLT+LRE G+EKC  YWP E    Y  F +   
Sbjct: 1701 IATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPM 1760

Query: 224  DMKECPEYTVRQ--LTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETA 281
                 P+Y +R+  +T     + R+++   F+ WP+   P++    +  + +V ++ E  
Sbjct: 1761 AEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQF 1820

Query: 282  AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQ 341
               GPI VHCSAG+GRTG FI   I  ++++  G VD+   V  LR  R  M+QT +QYQ
Sbjct: 1821 GQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQ 1880

Query: 342  FLHHTLALYAG 352
              +     Y G
Sbjct: 1881 LCYRAALEYLG 1891


>gi|148539860 protein tyrosine phosphatase, receptor type, T isoform 2
            precursor [Homo sapiens]
          Length = 1441

 Score =  185 bits (470), Expect = 5e-47
 Identities = 104/232 (44%), Positives = 134/232 (57%), Gaps = 10/232 (4%)

Query: 121  SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW 180
            +K+RY  I+    SRV L         DYINANYI GY  + + YIATQGPM  TV DFW
Sbjct: 914  NKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYH-RPRHYIATQGPMQETVKDFW 972

Query: 181  EMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQ 239
             M+WQE  + IVM+T L E G+ KCV YWP + E YG  ++ + + +   EY +R  T+Q
Sbjct: 973  RMIWQENSASIVMVTNLVEVGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQ 1032

Query: 240  YQ--EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVE--ESPETAAHPGPIVVHCSAGI 295
             +   E R ++   F++WPDH  P  A  LL  V +V+    PE     GPIVVHCSAG 
Sbjct: 1033 KKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEA----GPIVVHCSAGA 1088

Query: 296  GRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTL 347
            GRTGCFIA        +  G VDI   V +LR  R  ++QT EQY F+H  +
Sbjct: 1089 GRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAI 1140



 Score =  120 bits (302), Expect = 1e-27
 Identities = 84/267 (31%), Positives = 140/267 (52%), Gaps = 15/267 (5%)

Query: 96   QLEEEF--LKIPSNFVSPEDLDI---PGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYI 150
            Q+++EF  L I +  V PED  I   P +  K+R   +LP  +    L      E  +YI
Sbjct: 1174 QIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDG-ESSNYI 1232

Query: 151  NANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPT 210
            NA  +  +  +   ++ TQ P+PNTV+DFW +V+    S +VML ++ +  + C+ YWP 
Sbjct: 1233 NAALMDSHK-QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEM-DTAQFCMQYWPE 1290

Query: 211  EEE-TYGPFQIRI--QDMKECPEYTVRQLT--IQYQEERRSVKHILFSAWPDHQ-TPESA 264
            +    YGP Q+     D+ E   + + ++    + Q+  R V+H+ +  WP ++ TP S 
Sbjct: 1291 KTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSK 1350

Query: 265  GPLLRLVAEVEESPETA-AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIV 323
              LL++V  +E+  E      G  VVHC  G GR+G F A    C+ ++ +  +D+  IV
Sbjct: 1351 RSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1410

Query: 324  CQLRLDRGGMIQTAEQYQFLHHTLALY 350
              LR ++  M++T EQY+F++     Y
Sbjct: 1411 KTLRNNKSNMVETLEQYKFVYEVALEY 1437


>gi|148539858 protein tyrosine phosphatase, receptor type, T isoform 1
            precursor [Homo sapiens]
          Length = 1460

 Score =  185 bits (470), Expect = 5e-47
 Identities = 104/232 (44%), Positives = 134/232 (57%), Gaps = 10/232 (4%)

Query: 121  SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW 180
            +K+RY  I+    SRV L         DYINANYI GY  + + YIATQGPM  TV DFW
Sbjct: 933  NKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYH-RPRHYIATQGPMQETVKDFW 991

Query: 181  EMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQ 239
             M+WQE  + IVM+T L E G+ KCV YWP + E YG  ++ + + +   EY +R  T+Q
Sbjct: 992  RMIWQENSASIVMVTNLVEVGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQ 1051

Query: 240  YQ--EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVE--ESPETAAHPGPIVVHCSAGI 295
             +   E R ++   F++WPDH  P  A  LL  V +V+    PE     GPIVVHCSAG 
Sbjct: 1052 KKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEA----GPIVVHCSAGA 1107

Query: 296  GRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTL 347
            GRTGCFIA        +  G VDI   V +LR  R  ++QT EQY F+H  +
Sbjct: 1108 GRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAI 1159



 Score =  120 bits (302), Expect = 1e-27
 Identities = 84/267 (31%), Positives = 140/267 (52%), Gaps = 15/267 (5%)

Query: 96   QLEEEF--LKIPSNFVSPEDLDI---PGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYI 150
            Q+++EF  L I +  V PED  I   P +  K+R   +LP  +    L      E  +YI
Sbjct: 1193 QIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDG-ESSNYI 1251

Query: 151  NANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPT 210
            NA  +  +  +   ++ TQ P+PNTV+DFW +V+    S +VML ++ +  + C+ YWP 
Sbjct: 1252 NAALMDSHK-QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEM-DTAQFCMQYWPE 1309

Query: 211  EEE-TYGPFQIRI--QDMKECPEYTVRQLT--IQYQEERRSVKHILFSAWPDHQ-TPESA 264
            +    YGP Q+     D+ E   + + ++    + Q+  R V+H+ +  WP ++ TP S 
Sbjct: 1310 KTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSK 1369

Query: 265  GPLLRLVAEVEESPETA-AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIV 323
              LL++V  +E+  E      G  VVHC  G GR+G F A    C+ ++ +  +D+  IV
Sbjct: 1370 RSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1429

Query: 324  CQLRLDRGGMIQTAEQYQFLHHTLALY 350
              LR ++  M++T EQY+F++     Y
Sbjct: 1430 KTLRNNKSNMVETLEQYKFVYEVALEY 1456


>gi|208431815 protein tyrosine phosphatase, receptor type, K isoform a
            [Homo sapiens]
          Length = 1446

 Score =  184 bits (468), Expect = 8e-47
 Identities = 105/235 (44%), Positives = 135/235 (57%), Gaps = 10/235 (4%)

Query: 121  SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGY---DGKEKV--YIATQGPMPNT 175
            +K+RY  I+    SRV L   +     DYINANYI  +   DG ++   YIATQGP+  T
Sbjct: 913  AKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDIWLYRDGYQRPSHYIATQGPVHET 972

Query: 176  VSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVR 234
            V DFW M+WQE+ + IVM+T L E G+ KC  YWP + E YG F++   +M+   EY VR
Sbjct: 973  VYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVVR 1032

Query: 235  QLTIQYQ--EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCS 292
              T++ +   E R VK   F+ WPDH  P  A  LL  +  V+ S   +A  GPIVVHCS
Sbjct: 1033 TFTLERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPSA--GPIVVHCS 1090

Query: 293  AGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTL 347
            AG GRTGC+I   I     +  G VDI   V  LR  R  M+QT EQY F+H  +
Sbjct: 1091 AGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAI 1145



 Score =  103 bits (258), Expect = 2e-22
 Identities = 83/269 (30%), Positives = 128/269 (47%), Gaps = 21/269 (7%)

Query: 97   LEEEFLKIPSNFVSP----EDLDI---PGHASKDRYKTILPNPQSRVCLGRAQSQEDGDY 149
            L++EF  +  N V+P    ED  I   P +  K+R+  +LP  +    L      E  +Y
Sbjct: 1180 LKDEFQTL--NSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDG-ESSNY 1236

Query: 150  INANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWP 209
            INA  +  Y  +   +I TQ P+PNTV DFW +V+    + IVML ++ +  + C  YWP
Sbjct: 1237 INAALMDSYR-QPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEV-DLSQGCPQYWP 1294

Query: 210  TEEET-YGPFQIRIQDMK-ECPE----YTVRQLTIQYQEERRSVKHILFSAWPDH-QTPE 262
             E    YGP Q+       +C      + +  LT + QE    V+   +  W  H + P 
Sbjct: 1295 EEGMLRYGPIQVECMSCSMDCDVINRIFRICNLT-RPQEGYLMVQQFQYLGWASHREVPG 1353

Query: 263  SAGPLLRLVAEVEESPETAAH-PGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILG 321
            S    L+L+ +VE+  E      G  ++HC  G GR+G F A  I  + +K +  VD+  
Sbjct: 1354 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1413

Query: 322  IVCQLRLDRGGMIQTAEQYQFLHHTLALY 350
             V  LR  +  M++  EQY+F +     Y
Sbjct: 1414 AVKTLRNSKPNMVEAPEQYRFCYDVALEY 1442


>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
            isoform 4 precursor [Homo sapiens]
          Length = 1505

 Score =  184 bits (466), Expect = 1e-46
 Identities = 103/257 (40%), Positives = 142/257 (55%), Gaps = 8/257 (3%)

Query: 96   QLEEEFLKI-PSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANY 154
            +L +E+  I P    + E  ++  +  K+RY  ++    SRV L   +     DYINANY
Sbjct: 949  KLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANY 1008

Query: 155  IRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTE-E 212
            + GY   +  YIATQGP+P T  DFW MVW++  + IVM+T+L E  + KC  YWP    
Sbjct: 1009 VDGYRC-QNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGT 1067

Query: 213  ETYGPFQIRIQDMKECPEYTVRQLTIQYQ--EERRSVKHILFSAWPDHQTPESAGPLLRL 270
            ETYG  Q+ + D  E   + VR  ++      E+R V+   F+AWPDH  PE   P L  
Sbjct: 1068 ETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAF 1127

Query: 271  VAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR 330
            +  V+      A  GPIVVHCSAG+GRTGCFI      +++K    VD+ G V  +R  R
Sbjct: 1128 LRRVKTCNPPDA--GPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQR 1185

Query: 331  GGMIQTAEQYQFLHHTL 347
              M+QT +QY F+H  L
Sbjct: 1186 NYMVQTEDQYSFIHEAL 1202



 Score =  181 bits (458), Expect = 1e-45
 Identities = 97/251 (38%), Positives = 142/251 (56%), Gaps = 8/251 (3%)

Query: 106  SNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVY 165
            S F+S    ++P +  K+R   I+P   +RVCL   +  E  DYINA++I GY  ++K Y
Sbjct: 1252 SRFISA---NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYR-QQKAY 1307

Query: 166  IATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEET-YGPFQIRIQ 223
            IATQGP+  T  DFW M+W+   +++VMLT+LRE G+EKC  YWP E    Y  F +   
Sbjct: 1308 IATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPM 1367

Query: 224  DMKECPEYTVRQ--LTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETA 281
                 P+Y +R+  +T     + R+V+   F+ WP+   P+S    +  + +V ++ E  
Sbjct: 1368 AEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQF 1427

Query: 282  AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQ 341
               GPI VHCSAG+GRTG FI   I  ++++  G VDI   V  LR  R  M+QT ++YQ
Sbjct: 1428 GQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQ 1487

Query: 342  FLHHTLALYAG 352
            F +     Y G
Sbjct: 1488 FCYQAALEYLG 1498


>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
            isoform 2 precursor [Homo sapiens]
          Length = 1910

 Score =  184 bits (466), Expect = 1e-46
 Identities = 103/257 (40%), Positives = 142/257 (55%), Gaps = 8/257 (3%)

Query: 96   QLEEEFLKI-PSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANY 154
            +L +E+  I P    + E  ++  +  K+RY  ++    SRV L   +     DYINANY
Sbjct: 1354 KLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANY 1413

Query: 155  IRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTE-E 212
            + GY   +  YIATQGP+P T  DFW MVW++  + IVM+T+L E  + KC  YWP    
Sbjct: 1414 VDGYRC-QNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGT 1472

Query: 213  ETYGPFQIRIQDMKECPEYTVRQLTIQYQ--EERRSVKHILFSAWPDHQTPESAGPLLRL 270
            ETYG  Q+ + D  E   + VR  ++      E+R V+   F+AWPDH  PE   P L  
Sbjct: 1473 ETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAF 1532

Query: 271  VAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR 330
            +  V+      A  GPIVVHCSAG+GRTGCFI      +++K    VD+ G V  +R  R
Sbjct: 1533 LRRVKTCNPPDA--GPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQR 1590

Query: 331  GGMIQTAEQYQFLHHTL 347
              M+QT +QY F+H  L
Sbjct: 1591 NYMVQTEDQYSFIHEAL 1607



 Score =  181 bits (458), Expect = 1e-45
 Identities = 97/251 (38%), Positives = 142/251 (56%), Gaps = 8/251 (3%)

Query: 106  SNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVY 165
            S F+S    ++P +  K+R   I+P   +RVCL   +  E  DYINA++I GY  ++K Y
Sbjct: 1657 SRFISA---NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYR-QQKAY 1712

Query: 166  IATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEET-YGPFQIRIQ 223
            IATQGP+  T  DFW M+W+   +++VMLT+LRE G+EKC  YWP E    Y  F +   
Sbjct: 1713 IATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPM 1772

Query: 224  DMKECPEYTVRQ--LTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETA 281
                 P+Y +R+  +T     + R+V+   F+ WP+   P+S    +  + +V ++ E  
Sbjct: 1773 AEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQF 1832

Query: 282  AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQ 341
               GPI VHCSAG+GRTG FI   I  ++++  G VDI   V  LR  R  M+QT ++YQ
Sbjct: 1833 GQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQ 1892

Query: 342  FLHHTLALYAG 352
            F +     Y G
Sbjct: 1893 FCYQAALEYLG 1903


>gi|104487295 protein tyrosine phosphatase, receptor type, sigma
            isoform 3 precursor [Homo sapiens]
          Length = 1501

 Score =  184 bits (466), Expect = 1e-46
 Identities = 103/257 (40%), Positives = 142/257 (55%), Gaps = 8/257 (3%)

Query: 96   QLEEEFLKI-PSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANY 154
            +L +E+  I P    + E  ++  +  K+RY  ++    SRV L   +     DYINANY
Sbjct: 945  KLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANY 1004

Query: 155  IRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTE-E 212
            + GY   +  YIATQGP+P T  DFW MVW++  + IVM+T+L E  + KC  YWP    
Sbjct: 1005 VDGYRC-QNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGT 1063

Query: 213  ETYGPFQIRIQDMKECPEYTVRQLTIQYQ--EERRSVKHILFSAWPDHQTPESAGPLLRL 270
            ETYG  Q+ + D  E   + VR  ++      E+R V+   F+AWPDH  PE   P L  
Sbjct: 1064 ETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAF 1123

Query: 271  VAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR 330
            +  V+      A  GPIVVHCSAG+GRTGCFI      +++K    VD+ G V  +R  R
Sbjct: 1124 LRRVKTCNPPDA--GPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQR 1181

Query: 331  GGMIQTAEQYQFLHHTL 347
              M+QT +QY F+H  L
Sbjct: 1182 NYMVQTEDQYSFIHEAL 1198



 Score =  181 bits (458), Expect = 1e-45
 Identities = 97/251 (38%), Positives = 142/251 (56%), Gaps = 8/251 (3%)

Query: 106  SNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVY 165
            S F+S    ++P +  K+R   I+P   +RVCL   +  E  DYINA++I GY  ++K Y
Sbjct: 1248 SRFISA---NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYR-QQKAY 1303

Query: 166  IATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEET-YGPFQIRIQ 223
            IATQGP+  T  DFW M+W+   +++VMLT+LRE G+EKC  YWP E    Y  F +   
Sbjct: 1304 IATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPM 1363

Query: 224  DMKECPEYTVRQ--LTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETA 281
                 P+Y +R+  +T     + R+V+   F+ WP+   P+S    +  + +V ++ E  
Sbjct: 1364 AEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQF 1423

Query: 282  AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQ 341
               GPI VHCSAG+GRTG FI   I  ++++  G VDI   V  LR  R  M+QT ++YQ
Sbjct: 1424 GQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQ 1483

Query: 342  FLHHTLALYAG 352
            F +     Y G
Sbjct: 1484 FCYQAALEYLG 1494


>gi|18641364 protein tyrosine phosphatase, receptor type, C isoform
           3 precursor [Homo sapiens]
          Length = 1256

 Score =  184 bits (466), Expect = 1e-46
 Identities = 104/260 (40%), Positives = 146/260 (56%), Gaps = 12/260 (4%)

Query: 100 EFLKIPSNFVS--PEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRG 157
           EF  IP  F     ++   P + +K+RY  ILP   +RV L         +YINA+YI G
Sbjct: 606 EFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDG 665

Query: 158 YDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPTEEE--- 213
           +    K YIA QGP   TV DFW M+W+++ ++IVM+T+  EG + KC  YWP+ EE   
Sbjct: 666 FKEPRK-YIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTR 724

Query: 214 TYGPFQIRIQDMKECPEYTVRQLTIQYQEER---RSVKHILFSAWPDHQTPESAGPLLRL 270
            +G   ++I   K CP+Y +++L I  ++E+   R V HI F++WPDH  PE    LL+L
Sbjct: 725 AFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKL 784

Query: 271 VAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR 330
              V       +  GPIVVHCSAG+GRTG +I      + L+A  +VD+ G V +LR  R
Sbjct: 785 RRRVNAFSNFFS--GPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQR 842

Query: 331 GGMIQTAEQYQFLHHTLALY 350
             M+Q   QY  +H  L  Y
Sbjct: 843 CLMVQVEAQYILIHQALVEY 862



 Score =  145 bits (366), Expect = 5e-35
 Identities = 94/302 (31%), Positives = 155/302 (51%), Gaps = 34/302 (11%)

Query: 80   HPLTRWALQRQPPS-PKQLEEEFLKIPS--NFVSPEDLDIPGHASKDRYKTILPNPQSRV 136
            HP      +R PPS P  LE EF ++PS  ++ +    +   + SK+R   ++P   +RV
Sbjct: 876  HPYLHNMKKRDPPSEPSPLEAEFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRV 935

Query: 137  CLGR-------------------AQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVS 177
             L                     + S+E   YINA++I  Y  K +V IA QGP+  T+ 
Sbjct: 936  PLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSY-WKPEVMIAAQGPLKETIG 994

Query: 178  DFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQL 236
            DFW+M++Q +V +IVMLT+L+ G +E C  YW   ++TYG  ++ ++D  +   YT+R  
Sbjct: 995  DFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGKQTYGDIEVDLKDTDKSSTYTLRVF 1054

Query: 237  TIQY--QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEES-PETAAHPG-------P 286
             +++  +++ R+V    ++ W   Q P     L+ ++  V++  P+  +  G       P
Sbjct: 1055 ELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTP 1114

Query: 287  IVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHT 346
            +++HC  G  +TG F A     +  +    VDI  +V  LR  R GM+ T EQYQFL+  
Sbjct: 1115 LLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDV 1174

Query: 347  LA 348
            +A
Sbjct: 1175 IA 1176


>gi|18641347 protein tyrosine phosphatase, receptor type, C isoform
           1 precursor [Homo sapiens]
          Length = 1304

 Score =  184 bits (466), Expect = 1e-46
 Identities = 104/260 (40%), Positives = 146/260 (56%), Gaps = 12/260 (4%)

Query: 100 EFLKIPSNFVS--PEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRG 157
           EF  IP  F     ++   P + +K+RY  ILP   +RV L         +YINA+YI G
Sbjct: 654 EFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDG 713

Query: 158 YDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPTEEE--- 213
           +    K YIA QGP   TV DFW M+W+++ ++IVM+T+  EG + KC  YWP+ EE   
Sbjct: 714 FKEPRK-YIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTR 772

Query: 214 TYGPFQIRIQDMKECPEYTVRQLTIQYQEER---RSVKHILFSAWPDHQTPESAGPLLRL 270
            +G   ++I   K CP+Y +++L I  ++E+   R V HI F++WPDH  PE    LL+L
Sbjct: 773 AFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKL 832

Query: 271 VAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR 330
              V       +  GPIVVHCSAG+GRTG +I      + L+A  +VD+ G V +LR  R
Sbjct: 833 RRRVNAFSNFFS--GPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQR 890

Query: 331 GGMIQTAEQYQFLHHTLALY 350
             M+Q   QY  +H  L  Y
Sbjct: 891 CLMVQVEAQYILIHQALVEY 910



 Score =  145 bits (366), Expect = 5e-35
 Identities = 94/302 (31%), Positives = 155/302 (51%), Gaps = 34/302 (11%)

Query: 80   HPLTRWALQRQPPS-PKQLEEEFLKIPS--NFVSPEDLDIPGHASKDRYKTILPNPQSRV 136
            HP      +R PPS P  LE EF ++PS  ++ +    +   + SK+R   ++P   +RV
Sbjct: 924  HPYLHNMKKRDPPSEPSPLEAEFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRV 983

Query: 137  CLGR-------------------AQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVS 177
             L                     + S+E   YINA++I  Y  K +V IA QGP+  T+ 
Sbjct: 984  PLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSY-WKPEVMIAAQGPLKETIG 1042

Query: 178  DFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQL 236
            DFW+M++Q +V +IVMLT+L+ G +E C  YW   ++TYG  ++ ++D  +   YT+R  
Sbjct: 1043 DFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGKQTYGDIEVDLKDTDKSSTYTLRVF 1102

Query: 237  TIQY--QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEES-PETAAHPG-------P 286
             +++  +++ R+V    ++ W   Q P     L+ ++  V++  P+  +  G       P
Sbjct: 1103 ELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTP 1162

Query: 287  IVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHT 346
            +++HC  G  +TG F A     +  +    VDI  +V  LR  R GM+ T EQYQFL+  
Sbjct: 1163 LLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDV 1222

Query: 347  LA 348
            +A
Sbjct: 1223 IA 1224


>gi|18641362 protein tyrosine phosphatase, receptor type, C isoform
           2 precursor [Homo sapiens]
          Length = 1143

 Score =  184 bits (466), Expect = 1e-46
 Identities = 104/260 (40%), Positives = 146/260 (56%), Gaps = 12/260 (4%)

Query: 100 EFLKIPSNFVS--PEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRG 157
           EF  IP  F     ++   P + +K+RY  ILP   +RV L         +YINA+YI G
Sbjct: 493 EFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDG 552

Query: 158 YDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPTEEE--- 213
           +    K YIA QGP   TV DFW M+W+++ ++IVM+T+  EG + KC  YWP+ EE   
Sbjct: 553 FKEPRK-YIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTR 611

Query: 214 TYGPFQIRIQDMKECPEYTVRQLTIQYQEER---RSVKHILFSAWPDHQTPESAGPLLRL 270
            +G   ++I   K CP+Y +++L I  ++E+   R V HI F++WPDH  PE    LL+L
Sbjct: 612 AFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKL 671

Query: 271 VAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR 330
              V       +  GPIVVHCSAG+GRTG +I      + L+A  +VD+ G V +LR  R
Sbjct: 672 RRRVNAFSNFFS--GPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQR 729

Query: 331 GGMIQTAEQYQFLHHTLALY 350
             M+Q   QY  +H  L  Y
Sbjct: 730 CLMVQVEAQYILIHQALVEY 749



 Score =  145 bits (366), Expect = 5e-35
 Identities = 94/302 (31%), Positives = 155/302 (51%), Gaps = 34/302 (11%)

Query: 80   HPLTRWALQRQPPS-PKQLEEEFLKIPS--NFVSPEDLDIPGHASKDRYKTILPNPQSRV 136
            HP      +R PPS P  LE EF ++PS  ++ +    +   + SK+R   ++P   +RV
Sbjct: 763  HPYLHNMKKRDPPSEPSPLEAEFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRV 822

Query: 137  CLGR-------------------AQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVS 177
             L                     + S+E   YINA++I  Y  K +V IA QGP+  T+ 
Sbjct: 823  PLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSY-WKPEVMIAAQGPLKETIG 881

Query: 178  DFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQL 236
            DFW+M++Q +V +IVMLT+L+ G +E C  YW   ++TYG  ++ ++D  +   YT+R  
Sbjct: 882  DFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGKQTYGDIEVDLKDTDKSSTYTLRVF 941

Query: 237  TIQY--QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEES-PETAAHPG-------P 286
             +++  +++ R+V    ++ W   Q P     L+ ++  V++  P+  +  G       P
Sbjct: 942  ELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTP 1001

Query: 287  IVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHT 346
            +++HC  G  +TG F A     +  +    VDI  +V  LR  R GM+ T EQYQFL+  
Sbjct: 1002 LLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDV 1061

Query: 347  LA 348
            +A
Sbjct: 1062 IA 1063


>gi|104487002 protein tyrosine phosphatase, receptor type, D isoform 5
            precursor [Homo sapiens]
          Length = 1502

 Score =  181 bits (460), Expect = 7e-46
 Identities = 98/251 (39%), Positives = 142/251 (56%), Gaps = 8/251 (3%)

Query: 106  SNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVY 165
            S F+S    ++P +  K+R   I+P   +RVCL   +  E  DYINA++I GY  ++K Y
Sbjct: 1249 SRFISA---NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYR-QQKAY 1304

Query: 166  IATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEET-YGPFQIRIQ 223
            IATQGP+  T  DFW M+W+   +++VMLT+LRE G+EKC  YWP E    Y  F +   
Sbjct: 1305 IATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPM 1364

Query: 224  DMKECPEYTVRQ--LTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETA 281
                 P+Y +R+  +T     + R+V+   F+ WP+   P+S    +  + +V ++ E  
Sbjct: 1365 AEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQF 1424

Query: 282  AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQ 341
               GPI VHCSAG+GRTG FI   I  ++++  G VDI   V  LR  R  M+QT +QYQ
Sbjct: 1425 GQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQ 1484

Query: 342  FLHHTLALYAG 352
            F +     Y G
Sbjct: 1485 FSYRAALEYLG 1495



 Score =  181 bits (459), Expect = 9e-46
 Identities = 96/230 (41%), Positives = 130/230 (56%), Gaps = 7/230 (3%)

Query: 122  KDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWE 181
            K+RY  ++    SRV L   +     DY+NANYI GY  K+  YIATQG +P T  DFW 
Sbjct: 973  KNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYR-KQNAYIATQGSLPETFGDFWR 1031

Query: 182  MVWQEEVSLIVMLTQLRE-GKEKCVHYWPTE-EETYGPFQIRIQDMKECPEYTVRQLTIQ 239
            M+W++  + +VM+T+L E  + KC  YWP+   ET+G  Q+ + D  E   Y VR   + 
Sbjct: 1032 MIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALY 1091

Query: 240  YQ--EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGR 297
                 E+R V+   F+AWPDH  PE   P L  +  V+      A  GP+VVHCSAG+GR
Sbjct: 1092 KNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDA--GPMVVHCSAGVGR 1149

Query: 298  TGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTL 347
            TGCFI      +++K    VDI G V  +R  R  M+QT +QY F+H  L
Sbjct: 1150 TGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1199


>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
            precursor [Homo sapiens]
          Length = 1912

 Score =  181 bits (460), Expect = 7e-46
 Identities = 98/251 (39%), Positives = 142/251 (56%), Gaps = 8/251 (3%)

Query: 106  SNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVY 165
            S F+S    ++P +  K+R   I+P   +RVCL   +  E  DYINA++I GY  ++K Y
Sbjct: 1659 SRFISA---NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYR-QQKAY 1714

Query: 166  IATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEET-YGPFQIRIQ 223
            IATQGP+  T  DFW M+W+   +++VMLT+LRE G+EKC  YWP E    Y  F +   
Sbjct: 1715 IATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPM 1774

Query: 224  DMKECPEYTVRQ--LTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETA 281
                 P+Y +R+  +T     + R+V+   F+ WP+   P+S    +  + +V ++ E  
Sbjct: 1775 AEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQF 1834

Query: 282  AHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQ 341
               GPI VHCSAG+GRTG FI   I  ++++  G VDI   V  LR  R  M+QT +QYQ
Sbjct: 1835 GQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQ 1894

Query: 342  FLHHTLALYAG 352
            F +     Y G
Sbjct: 1895 FSYRAALEYLG 1905



 Score =  181 bits (459), Expect = 9e-46
 Identities = 96/230 (41%), Positives = 130/230 (56%), Gaps = 7/230 (3%)

Query: 122  KDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWE 181
            K+RY  ++    SRV L   +     DY+NANYI GY  K+  YIATQG +P T  DFW 
Sbjct: 1383 KNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYR-KQNAYIATQGSLPETFGDFWR 1441

Query: 182  MVWQEEVSLIVMLTQLRE-GKEKCVHYWPTE-EETYGPFQIRIQDMKECPEYTVRQLTIQ 239
            M+W++  + +VM+T+L E  + KC  YWP+   ET+G  Q+ + D  E   Y VR   + 
Sbjct: 1442 MIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALY 1501

Query: 240  YQ--EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGR 297
                 E+R V+   F+AWPDH  PE   P L  +  V+      A  GP+VVHCSAG+GR
Sbjct: 1502 KNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDA--GPMVVHCSAGVGR 1559

Query: 298  TGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTL 347
            TGCFI      +++K    VDI G V  +R  R  M+QT +QY F+H  L
Sbjct: 1560 TGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1609


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,467,670
Number of Sequences: 37866
Number of extensions: 814373
Number of successful extensions: 2652
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 103
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2057
Number of HSP's gapped (non-prelim): 146
length of query: 360
length of database: 18,247,518
effective HSP length: 103
effective length of query: 257
effective length of database: 14,347,320
effective search space: 3687261240
effective search space used: 3687261240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press