BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens] (835 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens] 1745 0.0 gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens] 1410 0.0 gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens] 1371 0.0 gi|23397681 egf-like module containing, mucin-like, hormone rece... 1056 0.0 gi|23397689 egf-like module containing, mucin-like, hormone rece... 1037 0.0 gi|23397685 egf-like module containing, mucin-like, hormone rece... 728 0.0 gi|23397693 egf-like module containing, mucin-like, hormone rece... 708 0.0 gi|23397683 egf-like module containing, mucin-like, hormone rece... 692 0.0 gi|23397691 egf-like module containing, mucin-like, hormone rece... 673 0.0 gi|23397687 egf-like module containing, mucin-like, hormone rece... 550 e-156 gi|40807489 egf-like module containing, mucin-like, hormone rece... 437 e-122 gi|133930786 egf-like module-containing mucin-like receptor 3 [H... 311 1e-84 gi|6912464 latrophilin 2 precursor [Homo sapiens] 294 2e-79 gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens] 291 1e-78 gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens] 291 1e-78 gi|148806925 EGF, latrophilin and seven transmembrane domain con... 291 1e-78 gi|163792198 latrophilin 3 precursor [Homo sapiens] 280 3e-75 gi|45433552 G protein-coupled receptor 133 [Homo sapiens] 191 2e-48 gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s... 189 7e-48 gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ... 166 8e-41 gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo sapi... 159 1e-38 gi|223556014 G-protein coupled receptor 113 isoform 2 [Homo sapi... 159 1e-38 gi|141802362 G-protein coupled receptor 113 isoform 3 [Homo sapi... 159 1e-38 gi|24430141 fibrillin 1 precursor [Homo sapiens] 158 2e-38 gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo... 158 2e-38 gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens] 154 2e-37 gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens] 154 2e-37 gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens] 154 2e-37 gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens] 154 2e-37 gi|56237021 fibrillin 3 precursor [Homo sapiens] 153 6e-37 >gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens] Length = 835 Score = 1745 bits (4519), Expect = 0.0 Identities = 835/835 (100%), Positives = 835/835 (100%) Query: 1 MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE 60 MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE Sbjct: 1 MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE 60 Query: 61 TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC 120 TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC Sbjct: 61 TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC 120 Query: 121 QQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNN 180 QQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNN Sbjct: 121 QQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNN 180 Query: 181 VGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 240 VGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG Sbjct: 181 VGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 240 Query: 241 WKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN 300 WKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN Sbjct: 241 WKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN 300 Query: 301 VIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTEL 360 VIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTEL Sbjct: 301 VIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTEL 360 Query: 361 TLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHS 420 TLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHS Sbjct: 361 TLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHS 420 Query: 421 KKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDP 480 KKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDP Sbjct: 421 KKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDP 480 Query: 481 PAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHY 540 PAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHY Sbjct: 481 PAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHY 540 Query: 541 DVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAG 600 DVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAG Sbjct: 541 DVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAG 600 Query: 601 IENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGY 660 IENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGY Sbjct: 601 IENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGY 660 Query: 661 GVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQ 720 GVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQ Sbjct: 661 GVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQ 720 Query: 721 KFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGA 780 KFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGA Sbjct: 721 KFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGA 780 Query: 781 FLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI 835 FLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI Sbjct: 781 FLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI 835 >gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens] Length = 742 Score = 1410 bits (3650), Expect = 0.0 Identities = 712/835 (85%), Positives = 720/835 (86%), Gaps = 93/835 (11%) Query: 1 MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE 60 MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE Sbjct: 1 MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE 60 Query: 61 TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC 120 TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC Sbjct: 61 TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC 120 Query: 121 QQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNN 180 C S C NT+GSY+C+C PG+K Sbjct: 121 SSGQHQCDSSTVCFNTVGSYSCRCRPGWK------------------------------- 149 Query: 181 VGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 240 P G PN +TVCED + F+T Sbjct: 150 -------------PRHGIPNNQKDTVCED---------------MTFST----------- 170 Query: 241 WKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN 300 W P G+ HSQTLSRFFDKVQDLGRDSKTSSAEVTIQN Sbjct: 171 WTPPPGV-----------------------HSQTLSRFFDKVQDLGRDSKTSSAEVTIQN 207 Query: 301 VIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTEL 360 VIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTEL Sbjct: 208 VIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTEL 267 Query: 361 TLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHS 420 TLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHS Sbjct: 268 TLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHS 327 Query: 421 KKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDP 480 KKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDP Sbjct: 328 KKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDP 387 Query: 481 PAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHY 540 PAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHY Sbjct: 388 PAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHY 447 Query: 541 DVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAG 600 DVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAG Sbjct: 448 DVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAG 507 Query: 601 IENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGY 660 IENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGY Sbjct: 508 IENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGY 567 Query: 661 GVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQ 720 GVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQ Sbjct: 568 GVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQ 627 Query: 721 KFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGA 780 KFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGA Sbjct: 628 KFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGA 687 Query: 781 FLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI 835 FLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI Sbjct: 688 FLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI 742 >gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens] Length = 786 Score = 1371 bits (3549), Expect = 0.0 Identities = 696/843 (82%), Positives = 712/843 (84%), Gaps = 65/843 (7%) Query: 1 MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE 60 MGGRVFLAFCVWLTL P Sbjct: 1 MGGRVFLAFCVWLTL------------------------------------------PGA 18 Query: 61 TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC 120 D CA C + S C N C C+PG+ S T E TC D++EC Sbjct: 19 ETQDSRGCAR----WCPQNSSCVNATA---CRCNPGFSSFSEIITTPTE---TCDDINEC 68 Query: 121 QQNPRL-CKSYGTCVNTLGSYTCQCLPGFK-------FIPEDPKVCTDVNECTSGQNPCH 172 ++ C + C NT GSY C C PG++ F E C DV+EC C Sbjct: 69 ATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCK 128 Query: 173 SSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGS 232 S C+N +GSY C+C PG++ IP P VC DVDECSSGQHQCDSSTVCFNTVGS Sbjct: 129 SYGTCVNTLGSYTCQCLPGFKFIPEDPK-----VCTDVDECSSGQHQCDSSTVCFNTVGS 183 Query: 233 YSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTS 292 YSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTS Sbjct: 184 YSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTS 243 Query: 293 SAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTY 352 SAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTY Sbjct: 244 SAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTY 303 Query: 353 ISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLA 412 ISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLA Sbjct: 304 ISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLA 363 Query: 413 NASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESS 472 NASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESS Sbjct: 364 NASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESS 423 Query: 473 DGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSS 532 DGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSS Sbjct: 424 DGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSS 483 Query: 533 FAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFV 592 FAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFV Sbjct: 484 FAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFV 543 Query: 593 GSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLST 652 GSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLST Sbjct: 544 GSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLST 603 Query: 653 RWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFV 712 RWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFV Sbjct: 604 RWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFV 663 Query: 713 TTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFT 772 TTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFT Sbjct: 664 TTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFT 723 Query: 773 ILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASE 832 ILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASE Sbjct: 724 ILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASE 783 Query: 833 SGI 835 SGI Sbjct: 784 SGI 786 >gi|23397681 egf-like module containing, mucin-like, hormone receptor-like sequence 2 isoform a [Homo sapiens] Length = 823 Score = 1056 bits (2731), Expect = 0.0 Identities = 508/811 (62%), Positives = 610/811 (75%), Gaps = 28/811 (3%) Query: 1 MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57 MGGRVFL AFCVWLTLPGAETQDSRGCARWCPQ+SSCVNATACRCNPGFSSFSEIITT Sbjct: 1 MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60 Query: 58 PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117 P ETCDDINECAT SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV Sbjct: 61 PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120 Query: 118 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHC 177 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK PEDPK+CTDVNECTSGQNPCHSSTHC Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHC 180 Query: 178 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 237 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC Sbjct: 181 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 240 Query: 238 RPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVT 297 RPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRD K A T Sbjct: 241 RPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDYKPGLANNT 300 Query: 298 IQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSN 357 IQ++++ +DEL+EAPGD+E L +H +A+ LL LED++R L+K+L G + P+ Sbjct: 301 IQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAG 360 Query: 358 TELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLN 417 TEL+L +Q++ D++VT+ Q+ A M+L+W A + DPGP+V G++SI M LLA A L Sbjct: 361 TELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGPSVVGLVSIPGMGKLLAEAPLV 420 Query: 418 LHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAG 477 L +KQ L E ++ ++ LS V S FLS+N+T+ L+SP+ F FSH Sbjct: 421 LEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSH--------- 471 Query: 478 RDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILM 537 + V+ PRQ++LC FW+ + GHWAT GC +G+++ ST C+C+HLSSFA+LM Sbjct: 472 -----RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLM 524 Query: 538 AHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGST 595 AHYDV ED LT+IT +GL++SL CLLL LTFLL + IQ + T++HL L +CLF+ Sbjct: 525 AHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHL 584 Query: 596 IFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY-----FLVVRVFQGQGL 650 +FL I+ G +V C ++AG LHY +LA WM LE L L+ VV Sbjct: 585 LFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRF 642 Query: 651 STRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVI 710 + + +GYGVP + V +SAA YG P CWL E+GF+W FLGPV I N V+ Sbjct: 643 MKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVL 702 Query: 711 FVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYV 770 F+ T+W L + S +N ++ L+ R L A AQLF+LGCTW G+ + V+ Y+ Sbjct: 703 FLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYL 762 Query: 771 FTILNCLQGAFLYLLHCLLNKKVREEYRKWA 801 FTI+N LQG F++L++CLL+++VRE+Y KW+ Sbjct: 763 FTIINSLQGVFIFLVYCLLSQQVREQYGKWS 793 >gi|23397689 egf-like module containing, mucin-like, hormone receptor-like sequence 2 isoform e [Homo sapiens] Length = 812 Score = 1037 bits (2681), Expect = 0.0 Identities = 503/811 (62%), Positives = 602/811 (74%), Gaps = 39/811 (4%) Query: 1 MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57 MGGRVFL AFCVWLTLPGAETQDSRGCARWCPQ+SSCVNATACRCNPGFSSFSEIITT Sbjct: 1 MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60 Query: 58 PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117 P ETCDDINECAT SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV Sbjct: 61 PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120 Query: 118 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHC 177 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK PEDPK+CTDVNECTSGQNPCHSSTHC Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHC 180 Query: 178 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 237 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC Sbjct: 181 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 240 Query: 238 RPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVT 297 RPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRD K A T Sbjct: 241 RPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDYKPGLANNT 300 Query: 298 IQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSN 357 IQ++++ +DEL+EAPGD+E L +H +A+ LL LED++R L+K+L G + P+ Sbjct: 301 IQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAG 360 Query: 358 TELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLN 417 TEL+L +Q++ D++VT+ Q+ A M+L+W A + DPG M LLA A L Sbjct: 361 TELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPG-----------MGKLLAEAPLV 409 Query: 418 LHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAG 477 L +KQ L E ++ ++ LS V S FLS+N+T+ L+SP+ F FSH Sbjct: 410 LEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSH--------- 460 Query: 478 RDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILM 537 + V+ PRQ++LC FW+ + GHWAT GC +G+++ ST C+C+HLSSFA+LM Sbjct: 461 -----RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLM 513 Query: 538 AHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGST 595 AHYDV ED LT+IT +GL++SL CLLL LTFLL + IQ + T++HL L +CLF+ Sbjct: 514 AHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHL 573 Query: 596 IFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY-----FLVVRVFQGQGL 650 +FL I+ G +V C ++AG LHY +LA WM LE L L+ VV Sbjct: 574 LFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRF 631 Query: 651 STRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVI 710 + + +GYGVP + V +SAA YG P CWL E+GF+W FLGPV I N V+ Sbjct: 632 MKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVL 691 Query: 711 FVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYV 770 F+ T+W L + S +N ++ L+ R L A AQLF+LGCTW G+ + V+ Y+ Sbjct: 692 FLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYL 751 Query: 771 FTILNCLQGAFLYLLHCLLNKKVREEYRKWA 801 FTI+N LQG F++L++CLL+++VRE+Y KW+ Sbjct: 752 FTIINSLQGVFIFLVYCLLSQQVREQYGKWS 782 >gi|23397685 egf-like module containing, mucin-like, hormone receptor-like sequence 2 isoform c [Homo sapiens] Length = 730 Score = 728 bits (1878), Expect = 0.0 Identities = 388/811 (47%), Positives = 497/811 (61%), Gaps = 121/811 (14%) Query: 1 MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57 MGGRVFL AFCVWLTLPGAETQDSRGCARWCPQ+SSCVNATACRCNPGFSSFSEIITT Sbjct: 1 MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60 Query: 58 PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117 P ETCDDINECAT SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV Sbjct: 61 PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120 Query: 118 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHC 177 DEC C S C NT+GSY+C+C PG+K Sbjct: 121 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK---------------------------- 152 Query: 178 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 237 P G PN +TVCED + F+T Sbjct: 153 ----------------PRHGIPNNQKDTVCED---------------MTFST-------- 173 Query: 238 RPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVT 297 W P G+ HSQTLSRFFDKVQDLGRD K A T Sbjct: 174 ---WTPPPGV-----------------------HSQTLSRFFDKVQDLGRDYKPGLANNT 207 Query: 298 IQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSN 357 IQ++++ +DEL+EAPGD+E L +H +A+ LL LED++R L+K+L G + P+ Sbjct: 208 IQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAG 267 Query: 358 TELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLN 417 TEL+L +Q++ D++VT+ Q+ A M+L+W A + DPGP+V G++SI M LLA A L Sbjct: 268 TELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGPSVVGLVSIPGMGKLLAEAPLV 327 Query: 418 LHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAG 477 L +KQ L E ++ ++ LS V S FLS+N+T+ L+SP+ F FSH Sbjct: 328 LEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSH--------- 378 Query: 478 RDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILM 537 + V+ PRQ++LC FW+ + GHWAT GC +G+++ ST C+C+HLSSFA+LM Sbjct: 379 -----RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLM 431 Query: 538 AHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGST 595 AHYDV ED LT+IT +GL++SL CLLL LTFLL + IQ + T++HL L +CLF+ Sbjct: 432 AHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHL 491 Query: 596 IFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY-----FLVVRVFQGQGL 650 +FL I+ G +V C ++AG LHY +LA WM LE L L+ VV Sbjct: 492 LFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRF 549 Query: 651 STRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVI 710 + + +GYGVP + V +SAA YG P CWL E+GF+W FLGPV I N V+ Sbjct: 550 MKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVL 609 Query: 711 FVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYV 770 F+ T+W L + S +N ++ L+ R L A AQLF+LGCTW G+ + V+ Y+ Sbjct: 610 FLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYL 669 Query: 771 FTILNCLQGAFLYLLHCLLNKKVREEYRKWA 801 FTI+N LQG F++L++CLL+++VRE+Y KW+ Sbjct: 670 FTIINSLQGVFIFLVYCLLSQQVREQYGKWS 700 >gi|23397693 egf-like module containing, mucin-like, hormone receptor-like sequence 2 isoform g [Homo sapiens] Length = 719 Score = 708 bits (1828), Expect = 0.0 Identities = 383/811 (47%), Positives = 489/811 (60%), Gaps = 132/811 (16%) Query: 1 MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57 MGGRVFL AFCVWLTLPGAETQDSRGCARWCPQ+SSCVNATACRCNPGFSSFSEIITT Sbjct: 1 MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60 Query: 58 PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117 P ETCDDINECAT SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV Sbjct: 61 PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120 Query: 118 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHC 177 DEC C S C NT+GSY+C+C PG+K Sbjct: 121 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK---------------------------- 152 Query: 178 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 237 P G PN +TVCED + F+T Sbjct: 153 ----------------PRHGIPNNQKDTVCED---------------MTFST-------- 173 Query: 238 RPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVT 297 W P G+ HSQTLSRFFDKVQDLGRD K A T Sbjct: 174 ---WTPPPGV-----------------------HSQTLSRFFDKVQDLGRDYKPGLANNT 207 Query: 298 IQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSN 357 IQ++++ +DEL+EAPGD+E L +H +A+ LL LED++R L+K+L G + P+ Sbjct: 208 IQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAG 267 Query: 358 TELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLN 417 TEL+L +Q++ D++VT+ Q+ A M+L+W A + DPG M LLA A L Sbjct: 268 TELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPG-----------MGKLLAEAPLV 316 Query: 418 LHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAG 477 L +KQ L E ++ ++ LS V S FLS+N+T+ L+SP+ F FSH Sbjct: 317 LEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSH--------- 367 Query: 478 RDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILM 537 + V+ PRQ++LC FW+ + GHWAT GC +G+++ ST C+C+HLSSFA+LM Sbjct: 368 -----RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLM 420 Query: 538 AHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGST 595 AHYDV ED LT+IT +GL++SL CLLL LTFLL + IQ + T++HL L +CLF+ Sbjct: 421 AHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHL 480 Query: 596 IFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY-----FLVVRVFQGQGL 650 +FL I+ G +V C ++AG LHY +LA WM LE L L+ VV Sbjct: 481 LFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRF 538 Query: 651 STRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVI 710 + + +GYGVP + V +SAA YG P CWL E+GF+W FLGPV I N V+ Sbjct: 539 MKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVL 598 Query: 711 FVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYV 770 F+ T+W L + S +N ++ L+ R L A AQLF+LGCTW G+ + V+ Y+ Sbjct: 599 FLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYL 658 Query: 771 FTILNCLQGAFLYLLHCLLNKKVREEYRKWA 801 FTI+N LQG F++L++CLL+++VRE+Y KW+ Sbjct: 659 FTIINSLQGVFIFLVYCLLSQQVREQYGKWS 689 >gi|23397683 egf-like module containing, mucin-like, hormone receptor-like sequence 2 isoform b [Homo sapiens] Length = 774 Score = 692 bits (1786), Expect = 0.0 Identities = 373/819 (45%), Positives = 490/819 (59%), Gaps = 93/819 (11%) Query: 1 MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57 MGGRVFL AFCVWLTL Sbjct: 1 MGGRVFLVFLAFCVWLTL------------------------------------------ 18 Query: 58 PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117 P D CA C + S C N C C+PG+ S T E TC D+ Sbjct: 19 PGAETQDSRGCAR----WCPQDSSCVNATA---CRCNPGFSSFSEIITTPME---TCDDI 68 Query: 118 DECQQNPRL-CKSYGTCVNTLGSYTCQCLPGFK-------FIPEDPKVCTDVNECTSGQN 169 +EC ++ C + C NT GSY C C PG++ F E C DV+EC Sbjct: 69 NECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPR 128 Query: 170 PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNT 229 C S C+N +GSY C+C PG++ P P +C DVDECSSGQHQCDSSTVCFNT Sbjct: 129 LCKSYGTCVNTLGSYTCQCLPGFKLKPEDPK-----LCTDVDECSSGQHQCDSSTVCFNT 183 Query: 230 VGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDS 289 VGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRD Sbjct: 184 VGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDY 243 Query: 290 KTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGP 349 K A TIQ++++ +DEL+EAPGD+E L +H +A+ LL LED++R L+K+L G Sbjct: 244 KPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGL 303 Query: 350 FTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTT 409 + P+ TEL+L +Q++ D++VT+ Q+ A M+L+W A + DPGP+V G++SI M Sbjct: 304 LNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGPSVVGLVSIPGMGK 363 Query: 410 LLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHL 469 LLA A L L +KQ L E ++ ++ LS V S FLS+N+T+ L+SP+ F FSH Sbjct: 364 LLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSH- 422 Query: 470 ESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSH 529 + V+ PRQ++LC FW+ + GHWAT GC +G+++ ST C+C+H Sbjct: 423 -------------RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTH 467 Query: 530 LSSFAILMAHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLC 587 LSSFA+LMAHYDV ED LT+IT +GL++SL CLLL LTFLL + IQ + T++HL L Sbjct: 468 LSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLS 527 Query: 588 ICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY-----FLVV 642 +CLF+ +FL I+ G +V C ++AG LHY +LA WM LE L L+ VV Sbjct: 528 LCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVV 585 Query: 643 RVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTF 702 + + +GYGVP + V +SAA YG P CWL E+GF+W FLGPV Sbjct: 586 NYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCA 645 Query: 703 IILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDD 762 I N V+F+ T+W L + S +N ++ L+ R L A AQLF+LGCTW G+ Sbjct: 646 IFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGP 705 Query: 763 RSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWA 801 + V+ Y+FTI+N LQG F++L++CLL+++VRE+Y KW+ Sbjct: 706 AARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWS 744 >gi|23397691 egf-like module containing, mucin-like, hormone receptor-like sequence 2 isoform f [Homo sapiens] Length = 763 Score = 673 bits (1736), Expect = 0.0 Identities = 368/819 (44%), Positives = 482/819 (58%), Gaps = 104/819 (12%) Query: 1 MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57 MGGRVFL AFCVWLTL Sbjct: 1 MGGRVFLVFLAFCVWLTL------------------------------------------ 18 Query: 58 PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117 P D CA C + S C N C C+PG+ S T E TC D+ Sbjct: 19 PGAETQDSRGCAR----WCPQDSSCVNATA---CRCNPGFSSFSEIITTPME---TCDDI 68 Query: 118 DECQQNPRL-CKSYGTCVNTLGSYTCQCLPGFK-------FIPEDPKVCTDVNECTSGQN 169 +EC ++ C + C NT GSY C C PG++ F E C DV+EC Sbjct: 69 NECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPR 128 Query: 170 PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNT 229 C S C+N +GSY C+C PG++ P P +C DVDECSSGQHQCDSSTVCFNT Sbjct: 129 LCKSYGTCVNTLGSYTCQCLPGFKLKPEDPK-----LCTDVDECSSGQHQCDSSTVCFNT 183 Query: 230 VGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDS 289 VGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRD Sbjct: 184 VGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDY 243 Query: 290 KTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGP 349 K A TIQ++++ +DEL+EAPGD+E L +H +A+ LL LED++R L+K+L G Sbjct: 244 KPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGL 303 Query: 350 FTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTT 409 + P+ TEL+L +Q++ D++VT+ Q+ A M+L+W A + DPG M Sbjct: 304 LNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPG-----------MGK 352 Query: 410 LLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHL 469 LLA A L L +KQ L E ++ ++ LS V S FLS+N+T+ L+SP+ F FSH Sbjct: 353 LLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSH- 411 Query: 470 ESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSH 529 + V+ PRQ++LC FW+ + GHWAT GC +G+++ ST C+C+H Sbjct: 412 -------------RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTH 456 Query: 530 LSSFAILMAHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLC 587 LSSFA+LMAHYDV ED LT+IT +GL++SL CLLL LTFLL + IQ + T++HL L Sbjct: 457 LSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLS 516 Query: 588 ICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY-----FLVV 642 +CLF+ +FL I+ G +V C ++AG LHY +LA WM LE L L+ VV Sbjct: 517 LCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVV 574 Query: 643 RVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTF 702 + + +GYGVP + V +SAA YG P CWL E+GF+W FLGPV Sbjct: 575 NYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCA 634 Query: 703 IILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDD 762 I N V+F+ T+W L + S +N ++ L+ R L A AQLF+LGCTW G+ Sbjct: 635 IFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGP 694 Query: 763 RSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWA 801 + V+ Y+FTI+N LQG F++L++CLL+++VRE+Y KW+ Sbjct: 695 AARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWS 733 >gi|23397687 egf-like module containing, mucin-like, hormone receptor-like sequence 2 isoform d [Homo sapiens] Length = 681 Score = 550 bits (1418), Expect = e-156 Identities = 286/641 (44%), Positives = 402/641 (62%), Gaps = 32/641 (4%) Query: 171 CHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSS-GQHQCDSSTVCFNT 229 C + C+N CRC PG+ P T C+D++EC++ + C + C+NT Sbjct: 33 CPQDSSCVNATA---CRCNPGFSSFSEIITTPMET-CDDINECATLSKVSCGKFSDCWNT 88 Query: 230 VGSYSCRCRPGWKPRHGIPN--NQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGR 287 GSY C C PG++P G N+ + C+DMTFSTWTPPPGVHSQTLSRFFDKVQDLGR Sbjct: 89 EGSYDCVCSPGYEPVSGAKTFKNESENTCQDMTFSTWTPPPGVHSQTLSRFFDKVQDLGR 148 Query: 288 DSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPK 347 D K A TIQ++++ +DEL+EAPGD+E L +H +A+ LL LED++R L+K+L Sbjct: 149 DYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSN 208 Query: 348 GPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNM 407 G + P+ TEL+L +Q++ D++VT+ Q+ A M+L+W A + DPGP+V G++SI M Sbjct: 209 GLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGPSVVGLVSIPGM 268 Query: 408 TTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFS 467 LLA A L L +KQ L E ++ ++ LS V S FLS+N+T+ L+SP+ F FS Sbjct: 269 GKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFS 328 Query: 468 HLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQC 527 H + V+ PRQ++LC FW+ + GHWAT GC +G+++ ST C+C Sbjct: 329 H--------------RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRC 372 Query: 528 SHLSSFAILMAHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLH 585 +HLSSFA+LMAHYDV ED LT+IT +GL++SL CLLL LTFLL + IQ + T++HL Sbjct: 373 THLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQ 432 Query: 586 LCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY-----FL 640 L +CLF+ +FL I+ G +V C ++AG LHY +LA WM LE L L+ Sbjct: 433 LSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLT 490 Query: 641 VVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPV 700 VV + + +GYGVP + V +SAA YG P CWL E+GF+W FLGPV Sbjct: 491 VVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPV 550 Query: 701 TFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIF 760 I N V+F+ T+W L + S +N ++ L+ R L A AQLF+LGCTW G+ Sbjct: 551 CAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQV 610 Query: 761 DDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWA 801 + V+ Y+FTI+N LQG F++L++CLL+++VRE+Y KW+ Sbjct: 611 GPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWS 651 Score = 247 bits (630), Expect = 4e-65 Identities = 113/120 (94%), Positives = 115/120 (95%), Gaps = 3/120 (2%) Query: 1 MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57 MGGRVFL AFCVWLTLPGAETQDSRGCARWCPQ+SSCVNATACRCNPGFSSFSEIITT Sbjct: 1 MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60 Query: 58 PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117 P ETCDDINECAT SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQD+ Sbjct: 61 PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDM 120 >gi|40807489 egf-like module containing, mucin-like, hormone receptor-like sequence 1 [Homo sapiens] Length = 886 Score = 437 bits (1125), Expect = e-122 Identities = 275/853 (32%), Positives = 425/853 (49%), Gaps = 105/853 (12%) Query: 16 PGAETQDSRGCARW---CPQNSSCVNATA---CRCNPGFSSFSEIITTPTE----TCDDI 65 PG +D C++ C NSSC N + C C GFSS + P + +C DI Sbjct: 74 PGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133 Query: 66 NECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPR 125 NEC T S C + SDC N+ GSY C C G+ +TC+DVDEC +PR Sbjct: 134 NECLTSSV--CPEHSDCVNSMGSYSCSCQVGFI----------SRNSTCEDVDECA-DPR 180 Query: 126 LCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKV------CTDVNECTSGQNPCHSSTHCLN 179 C + TC NT+G+Y+C C PGF+ C D++ECT C ++ C N Sbjct: 181 ACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTE---MCPINSTCTN 237 Query: 180 NVGSYQCRCRPGWQPIPGSPNGPNNTV-CEDVDECSSGQHQCDSSTVCFNTVGSYSCRCR 238 GSY C C PG+ P G N + V C D+DEC C +++C N +GSYSC C Sbjct: 238 TPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCI 297 Query: 239 PGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVT- 297 G+ P + C+ + F + + ++Q + A V+ Sbjct: 298 AGFHPNPEGSQKDGNFSCQRVLFKC--------KEDVIPDNKQIQQCQEGTAVKPAYVSF 349 Query: 298 ---IQNVIKLVDELMEAPGDVEALAP------PVRHLIAT------QLLSNLEDIMRILA 342 I N+ ++D++ E V +L PV I+T + S+L + Sbjct: 350 CAQINNIFSVLDKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLESV 409 Query: 343 KSLPKGPF----TYISPS------NTELTLMIQERGDKNVTMG--QSSARMKLNWAVAAG 390 +S+ F I+P+ + E ++ +E ++NVT+ +MK+ + Sbjct: 410 ESMTLASFWKPSANITPAVRTEYLDIESKVINKECSEENVTLDLVAKGDKMKIGCSTIEE 469 Query: 391 AEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFL 450 +E +S M ++L H E ++L+ S V + Sbjct: 470 SESTETTGVAFVSFVGMESVLNERFFKDHQAPLTTSE---------IKLKMNSRVVGGIM 520 Query: 451 SHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWAT 510 + + PI++ +++ P K P +C W +D +GG W + Sbjct: 521 TGEKKDGFSDPIIYTLENIQ---------PKQKFERP------ICVSWSTDV-KGGRWTS 564 Query: 511 EGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVE-DWKLTLITRVGLALSLFCLLLCILTF 569 GC +L + T C C+ +++ A++MA ++ D+ L +I+ VG+ +SL CL+L I TF Sbjct: 565 FGCVILEASETYTICSCNQMANLAVIMASGELTMDFSLYIISHVGIIISLVCLVLAIATF 624 Query: 570 LLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCW 629 LL R I+ T +HLHLC+CL + T+FLAGI ++G C ++AG LHY FLA F W Sbjct: 625 LLCRSIRNHNTYLHLHLCVCLLLAKTLFLAGIHKTDNKMG--CAIIAGFLHYLFLACFFW 682 Query: 630 MSLEGLELYFLV-----VRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYC 684 M +E + L+ +V V F + + +C GYG+P+L+V +SA++ +GYG C Sbjct: 683 MLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRC 742 Query: 685 WLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIA 744 WL+ E GF+WSFLGPV +I+ N+++ T+W L Q+ S +N ++ LK R LT A A Sbjct: 743 WLNTETGFIWSFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFA 802 Query: 745 QLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLV 804 QLF+LGC+WV G+F + V+ Y+FTI+N LQGAF++L+HCLLN +VREEY++W + Sbjct: 803 QLFILGCSWVLGIFQIGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQVREEYKRW---I 859 Query: 805 AGGSKYSEFTSTT 817 G +K S + T+ Sbjct: 860 TGKTKPSSQSQTS 872 Score = 132 bits (333), Expect = 1e-30 Identities = 75/194 (38%), Positives = 100/194 (51%), Gaps = 22/194 (11%) Query: 76 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVN 135 C ++ C NT SY C C G+ +G FK+ C+D+DEC Q+P+ C +C N Sbjct: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR-CKDIDECSQSPQPCGPNSSCKN 99 Query: 136 TLGSYTCQCLPGFK------FIPEDPK--VCTDVNEC-TSGQNPCHSSTHCLNNVGSYQC 186 G Y C CL GF ++P P CTD+NEC TS P HS C+N++GSY C Sbjct: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSD--CVNSMGSYSC 157 Query: 187 RCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHG 246 C+ G+ N+ CEDVDEC+ C C NTVG+YSC C PG++ G Sbjct: 158 SCQVGFI--------SRNSTCEDVDECAD-PRACPEHATCNNTVGNYSCFCNPGFESSSG 208 Query: 247 IPNNQ-KDTVCEDM 259 + Q CED+ Sbjct: 209 HLSFQGLKASCEDI 222 Score = 97.8 bits (242), Expect = 4e-20 Identities = 55/161 (34%), Positives = 78/161 (48%), Gaps = 25/161 (15%) Query: 108 NESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIP-----EDPKV-CTDV 161 N N C+D LC +Y TC NT+ SY C C GF +DP V C D+ Sbjct: 29 NTKGNNCRD-------STLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDI 81 Query: 162 NECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGS---PNGPNNTVCEDVDECSSGQH 218 +EC+ PC ++ C N G Y+C C G+ G+ P P N C D++EC + Sbjct: 82 DECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS- 140 Query: 219 QCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDM 259 C + C N++GSYSC C+ G+ R ++ CED+ Sbjct: 141 VCPEHSDCVNSMGSYSCSCQVGFISR--------NSTCEDV 173 >gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo sapiens] Length = 652 Score = 311 bits (798), Expect = 1e-84 Identities = 209/672 (31%), Positives = 326/672 (48%), Gaps = 90/672 (13%) Query: 171 CHSSTHCLNNVGSYQCRCRPGWQPIPGSP--NGPNNTVCEDVDECSSGQH-QCDSSTVCF 227 C + C+NN C C G+ G P T C D++EC+ C + VC+ Sbjct: 31 CPPNASCVNNT---HCTCNHGYTSGSGQKLFTFPLET-CNDINECTPPYSVYCGFNAVCY 86 Query: 228 NTVGSYSCRCRPGWKPRHGIP--NNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDL 285 N GS+ C+C PG++ G +N + C+D T S T + L + DK + L Sbjct: 87 NVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDTTSSKTTEG----RKELQKIVDKFESL 142 Query: 286 ----------GRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLE 335 GR +S+A +++V V E AL P + ++ Q Sbjct: 143 LTNQTLWRTEGRQEISSTATTILRDVESKVLET--------ALKDPEQKVLKIQ-----N 189 Query: 336 DIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPG 395 D + I +++ +ER N+ + +S ++ + + + G Sbjct: 190 DSVAIETQAITDN--------------CSEERKTFNLNVQMNSMDIRCSDIIQGDTQ--G 233 Query: 396 PAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNT 455 P+ +S ++ ++ KK +++Y +S V S + Sbjct: 234 PSAIAFISYSSLGNIINATFFEEMDKK----DQVYLNS----------QVVSAAIGPKRN 279 Query: 456 KELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQV 515 L+ + F H++ + P K V C +WKS + +G W+ +GC + Sbjct: 280 VSLSKSVTLTFQHVKMT-------PSTKKVF--------CVYWKS-TGQGSQWSRDGCFL 323 Query: 516 LGSKNGSTTCQCSHLSSFAILMA-HYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRP 574 + T C CSHLSSFA+LMA ED LT+IT VGL++SL CLLL LTFLL + Sbjct: 324 IHVNKSHTMCNCSHLSSFAVLMALTSQEEDPVLTVITYVGLSVSLLCLLLAALTFLLCKA 383 Query: 575 IQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEG 634 I+ + T++HL L +CLF+ +FL GI+ +V C ++AG LHY +LAAF WM LEG Sbjct: 384 IRNTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKV--LCSIIAGALHYLYLAAFTWMLLEG 441 Query: 635 LELYF----LVVRVFQGQGLSTRWLCL-IGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFE 689 + L+ L V + +W+ +GYGVP + V +SAA + YG CWL + Sbjct: 442 VHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLD 501 Query: 690 QGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLL 749 QGF+WSFLGPV I N V+F+ W L +K S +N ++ ++ R L A AQLF+L Sbjct: 502 QGFMWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFIL 561 Query: 750 GCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSK 809 GCTW GL + V+ Y+FTI+N LQG F++L++CLL+++V+++Y+KW + Sbjct: 562 GCTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREIVKSKS 621 Query: 810 YSEFTSTTSGTG 821 SE + +S G Sbjct: 622 ESETYTLSSKMG 633 Score = 114 bits (285), Expect = 4e-25 Identities = 55/109 (50%), Positives = 69/109 (63%), Gaps = 2/109 (1%) Query: 10 CVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFS--EIITTPTETCDDINE 67 C L+L GA TQ ++ CP N+SCVN T C CN G++S S ++ T P ETC+DINE Sbjct: 11 CFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLETCNDINE 70 Query: 68 CATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQD 116 C P V CG + C+N EGS+ C C PGY SG + F N +ENTCQD Sbjct: 71 CTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQD 119 Score = 53.9 bits (128), Expect = 6e-07 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 8/105 (7%) Query: 72 SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRL-CKSY 130 +K SC K + + C C+ GY SG K F E TC D++EC + C Sbjct: 24 TKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLE-TCNDINECTPPYSVYCGFN 82 Query: 131 GTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSST 175 C N GS+ CQC+PG++ + + S +N C +T Sbjct: 83 AVCYNVEGSFYCQCVPGYRLHSGNEQF------SNSNENTCQDTT 121 >gi|6912464 latrophilin 2 precursor [Homo sapiens] Length = 1403 Score = 294 bits (753), Expect = 2e-79 Identities = 153/368 (41%), Positives = 218/368 (59%), Gaps = 30/368 (8%) Query: 444 AVNSIFLSHNNTKE-----LNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFW 498 AVNS +S + KE L P+LF H++ P C+FW Sbjct: 735 AVNSHVISVSINKESSRVYLTDPVLFTLPHID----------------PDNYFNANCSFW 778 Query: 499 K-SDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYD------VEDWKLTLIT 551 S+ G+W+T+GC+++ + TTC CSHL++FAILMAH + V + LT+IT Sbjct: 779 NYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDGVHELLLTVIT 838 Query: 552 RVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLR 611 VG+ +SL CL +CI TF R +Q R TIH +LCI LF+ IFL GI+ + + Sbjct: 839 WVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKT--KYAIA 896 Query: 612 CRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSA 671 C + AGLLH+ FLAAF WM LEG++LY ++V VF+ + ++ + GY P +VGVSA Sbjct: 897 CPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSA 956 Query: 672 AIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKK 731 AI K YG + CWL + F+WSF+GPVTFIIL N + V T+ K+ + + + PD + Sbjct: 957 AIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNIIFLVITLCKMVKHSNTLKPDSSR 1016 Query: 732 LKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNK 791 L+ ++ + A A L LLG TW FGL ++ ++V+ Y+FTI N QG F+++ HC L K Sbjct: 1017 LENIKSWVLGAFALLCLLGLTWSFGLLFINEETIVMAYLFTIFNAFQGVFIFIFHCALQK 1076 Query: 792 KVREEYRK 799 KVR+EY K Sbjct: 1077 KVRKEYGK 1084 >gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens] Length = 1474 Score = 291 bits (746), Expect = 1e-78 Identities = 159/399 (39%), Positives = 232/399 (58%), Gaps = 35/399 (8%) Query: 445 VNSIFLSHNNTKE-----LNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWK 499 VNS ++ + KE L P++F +HLE + C+FW Sbjct: 763 VNSQVIAASINKESSRVFLMDPVIFTVAHLEDKNHFNAN----------------CSFWN 806 Query: 500 -SDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWK-----LTLITRV 553 S+ G+W+T+GC+++ S TTC CSHL++FA+LMAH ++ + L++IT V Sbjct: 807 YSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHREIYQGRINELLLSVITWV 866 Query: 554 GLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCR 613 G+ +SL CL +CI TF +R +Q R TIH +LCI LF+ +FL GI+ Q + C Sbjct: 867 GIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDKT--QYEIACP 924 Query: 614 LVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAI 673 + AGLLHY FLAAF W+ LEG+ LY L+V VF+ + T++ L GY P L+VG++AAI Sbjct: 925 IFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLGGYCFPALVVGIAAAI 984 Query: 674 YSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLK 733 + YG + CWL + F+WSF+GPV+F+I+ N V + T+ K+ + S + PD +L Sbjct: 985 DYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLD 1044 Query: 734 KARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKV 793 ++ + AIA LFLLG TW FGL + S+V+ Y+FT N QG F+++ HC L KKV Sbjct: 1045 NIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAYLFTTFNAFQGVFIFVFHCALQKKV 1104 Query: 794 REEYRKWACLVAGGSKYSEFTSTTSGT-GHNQTRALRAS 831 +EY K CL Y S GT G +T A+R++ Sbjct: 1105 HKEYSK--CL---RHSYCCIRSPPGGTHGSLKTSAMRSN 1138 >gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens] Length = 1469 Score = 291 bits (746), Expect = 1e-78 Identities = 159/399 (39%), Positives = 232/399 (58%), Gaps = 35/399 (8%) Query: 445 VNSIFLSHNNTKE-----LNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWK 499 VNS ++ + KE L P++F +HLE + C+FW Sbjct: 758 VNSQVIAASINKESSRVFLMDPVIFTVAHLEDKNHFNAN----------------CSFWN 801 Query: 500 -SDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWK-----LTLITRV 553 S+ G+W+T+GC+++ S TTC CSHL++FA+LMAH ++ + L++IT V Sbjct: 802 YSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHREIYQGRINELLLSVITWV 861 Query: 554 GLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCR 613 G+ +SL CL +CI TF +R +Q R TIH +LCI LF+ +FL GI+ Q + C Sbjct: 862 GIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDKT--QYEIACP 919 Query: 614 LVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAI 673 + AGLLHY FLAAF W+ LEG+ LY L+V VF+ + T++ L GY P L+VG++AAI Sbjct: 920 IFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLGGYCFPALVVGIAAAI 979 Query: 674 YSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLK 733 + YG + CWL + F+WSF+GPV+F+I+ N V + T+ K+ + S + PD +L Sbjct: 980 DYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLD 1039 Query: 734 KARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKV 793 ++ + AIA LFLLG TW FGL + S+V+ Y+FT N QG F+++ HC L KKV Sbjct: 1040 NIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAYLFTTFNAFQGVFIFVFHCALQKKV 1099 Query: 794 REEYRKWACLVAGGSKYSEFTSTTSGT-GHNQTRALRAS 831 +EY K CL Y S GT G +T A+R++ Sbjct: 1100 HKEYSK--CL---RHSYCCIRSPPGGTHGSLKTSAMRSN 1133 >gi|148806925 EGF, latrophilin and seven transmembrane domain containing 1 [Homo sapiens] Length = 690 Score = 291 bits (746), Expect = 1e-78 Identities = 209/702 (29%), Positives = 328/702 (46%), Gaps = 104/702 (14%) Query: 158 CTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQ 217 C+ CT + PC + C G C C G+ +G T+CED +EC + Sbjct: 16 CSYTQNCT--KTPCLPNAKCEIRNGIEACYCNMGF-------SGNGVTICEDDNECGNLT 66 Query: 218 HQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVH------ 271 C + C NT GSY C C PG++ +NQ + D T H Sbjct: 67 QSCGENANCTNTEGSYYCMCVPGFRSS----SNQDRFITNDGTVCIENVNANCHLDNVCI 122 Query: 272 ----SQTLSR--------------FFDKVQDL-------------------GRDSKTSSA 294 ++TL++ + + V DL G + T SA Sbjct: 123 AANINKTLTKIRSIKEPVALLQEVYRNSVTDLSPTDIITYIEILAESSSLLGYKNNTISA 182 Query: 295 EVTIQN-----VIKLVDELMEAPGDV--EALAPPVRHLIATQLLSNLEDIMRILAKSLPK 347 + T+ N +K V+ ++ V + L+ R T+L+ +E +++S K Sbjct: 183 KDTLSNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRISQSFQK 242 Query: 348 GPFTYISPSNTELTLMIQERGDKNVT-----MGQSSARMKLNWAVAAGAEDPGPAVAGIL 402 T ++T++ L + N+ M + + A + G + Sbjct: 243 T--TEFDTNSTDIALKVFFFDSYNMKHIHPHMNMDGDYINIFPKRKAAYDSNGNVAVAFV 300 Query: 403 SIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHN--NTKELNS 460 +++ LL+++ L + + E E R +S+V S+ +S N EL Sbjct: 301 YYKSIGPLLSSSDNFLLKPQNYDNSEEEE--------RVISSVISVSMSSNPPTLYELEK 352 Query: 461 PILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDR-GGHWATEGCQVLGSK 519 I F SH + +D R LCAFW D G W++EGC++ S Sbjct: 353 -ITFTLSHRKVTD----------------RYRSLCAFWNYSPDTMNGSWSSEGCELTYSN 395 Query: 520 NGSTTCQCSHLSSFAILMAH---YDVEDWK-LTLITRVGLALSLFCLLLCILTFLLVRPI 575 T+C+C+HL+ FAILM+ ++D+ LT IT++G+ +SL CL +CI TF I Sbjct: 396 ETHTSCRCNHLTHFAILMSSGPSIGIKDYNILTRITQLGIIISLICLAICIFTFWFFSEI 455 Query: 576 QGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGL 635 Q +RTTIH +LC LF+ +FL GI + L C ++AGLLHY FLAAF WM +EG+ Sbjct: 456 QSTRTTIHKNLCCSLFLAELVFLVGINTNTNK--LFCSIIAGLLHYFFLAAFAWMCIEGI 513 Query: 636 ELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWS 695 LY +VV V +G + + GY P ++VG SAA+ + YG + CWL E F+WS Sbjct: 514 HLYLIVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWS 573 Query: 696 FLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVF 755 F+GP IIL N + F ++K+ + + + P++ + R+ A+A LFLLG TW+F Sbjct: 574 FIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTWIF 633 Query: 756 GLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEY 797 G+ S+V Y+FT+ N QG F++L C+L++K++EEY Sbjct: 634 GVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEY 675 Score = 59.3 bits (142), Expect = 1e-08 Identities = 33/88 (37%), Positives = 42/88 (47%), Gaps = 10/88 (11%) Query: 30 CPQNSSCV---NATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTE 86 C N+ C AC CN GFS I C+D NEC ++ SCG+ ++C NTE Sbjct: 27 CLPNAKCEIRNGIEACYCNMGFSGNGVTI------CEDDNECGNLTQ-SCGENANCTNTE 79 Query: 87 GSYDCVCSPGYEPVSGAKTFKNESENTC 114 GSY C+C PG+ S F C Sbjct: 80 GSYYCMCVPGFRSSSNQDRFITNDGTVC 107 Score = 52.0 bits (123), Expect = 2e-06 Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 11/109 (10%) Query: 72 SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYG 131 +K C + C G C C+ G F C+D +EC + C Sbjct: 23 TKTPCLPNAKCEIRNGIEACYCNMG---------FSGNGVTICEDDNECGNLTQSCGENA 73 Query: 132 TCVNTLGSYTCQCLPGFKFIP-EDPKVCTDVNECTSGQNP-CHSSTHCL 178 C NT GSY C C+PGF+ +D + D C N CH C+ Sbjct: 74 NCTNTEGSYYCMCVPGFRSSSNQDRFITNDGTVCIENVNANCHLDNVCI 122 >gi|163792198 latrophilin 3 precursor [Homo sapiens] Length = 1469 Score = 280 bits (717), Expect = 3e-75 Identities = 155/394 (39%), Positives = 227/394 (57%), Gaps = 25/394 (6%) Query: 450 LSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELL----CAFWK-SDSDR 504 LS N++ +NSP++ A + E S+ DP V + E C+FW S Sbjct: 769 LSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTM 828 Query: 505 GGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVE------DWKLTLITRVGLALS 558 G+W+T+GC++L + TTC C+HL++FA+LMAH +V+ D L +IT VG+ LS Sbjct: 829 TGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLS 888 Query: 559 LFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGL 618 L CLL+CI TF R +Q R TIH +LCI LFV +FL GI + C + A L Sbjct: 889 LVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIA--CAVFAAL 946 Query: 619 LHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGY 678 LH+ FLAAF WM LEG++LY ++V VF+ + ++ L+GYG+P LIV VSAA+ + Y Sbjct: 947 LHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSY 1006 Query: 679 GRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKK---- 734 G + CWL + F+WSF+GP T II+ N + ++K+ + + P+ L Sbjct: 1007 GTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNINYE 1066 Query: 735 -----ARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLL 789 ++ I AIA L LLG TW FGL ++ ++++ Y+FTI N LQG F+++ HC+L Sbjct: 1067 DNRPFIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHCVL 1126 Query: 790 NKKVREEYRKWA---CLVAGGSKYSEFTSTTSGT 820 KKVR+EY K C ++ S + TSG+ Sbjct: 1127 QKKVRKEYGKCLRTHCCSGKSTESSIGSGKTSGS 1160 >gi|45433552 G protein-coupled receptor 133 [Homo sapiens] Length = 874 Score = 191 bits (486), Expect = 2e-48 Identities = 113/316 (35%), Positives = 171/316 (54%), Gaps = 19/316 (6%) Query: 495 CAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVE-----DWKLTL 549 CAF S G W+ GC + + C+C+HL++FAILM +E L+ Sbjct: 510 CAFLDFSSGEGV-WSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVALSS 568 Query: 550 ITRVGLALSLFCLLLCILTFLL---VRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGG 606 I+ VG +LS+ CL+ ++TF + V I+ R IH +L + V + L E G Sbjct: 569 ISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEPG 628 Query: 607 QVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLI 666 C+++A LLHY FL+AF WM +EGL LY +V++VF + R+ +G+G PLLI Sbjct: 629 TTP--CQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGFPLLI 686 Query: 667 VGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEIN 726 +S + YG CWL G +W+F+ P F+I+ N I + +T+ S+I+ Sbjct: 687 CIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIA----VTRVISQIS 742 Query: 727 PDMKKL---KKARALTITAIAQLF-LLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFL 782 D K+ A LT A+A L +LG +WVFG+ + ++V Y+F LN LQG F+ Sbjct: 743 ADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFI 802 Query: 783 YLLHCLLNKKVREEYR 798 +L HCLLN +VR ++ Sbjct: 803 FLFHCLLNSEVRAAFK 818 >gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo sapiens] Length = 3014 Score = 189 bits (481), Expect = 7e-48 Identities = 122/408 (29%), Positives = 196/408 (48%), Gaps = 39/408 (9%) Query: 426 LEEIYESSIRGVQLRRLSAVNSIFLSHNNTKE-------LNSPILFAFSHLESSDGEAGR 478 L E Y+ R ++L +N+ +S E L P+L F+ LE + Sbjct: 2351 LPERYDPDRRSLRLPHRPIINTPMVSTLVYSEGAPLPRPLERPVLVEFALLEVEE----- 2405 Query: 479 DPPAKDVMPGPRQELLCAFWKSDSDRGGH--WATEGCQVLGSKNGSTTCQCSHLSSFAIL 536 R + +C FW GG W+ GC++L CQCSH +SFA+L Sbjct: 2406 -----------RTKPVCVFWNHSLAVGGTGGWSARGCELLSRNRTHVACQCSHTASFAVL 2454 Query: 537 M---AHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVG 593 M + E L ++T ++LSL LL+ + LVR ++ + +IH HL + LF+ Sbjct: 2455 MDISRRENGEVLPLKIVTYAAVSLSLAALLVAFVLLSLVRMLRSNLHSIHKHLAVALFLS 2514 Query: 594 STIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTR 653 +F+ GI C +VA LLHY +++ F W +E L +Y ++ V R Sbjct: 2515 QLVFVIGINQTENP--FLCTVVAILLHYIYMSTFAWTLVESLHVYRMLTEVRNIDTGPMR 2572 Query: 654 WLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVT 713 + ++G+G+P ++ G++ + +GYG P +CWL + +WSF GP+ +I+ N V V Sbjct: 2573 FYYVVGWGIPAIVTGLAVGLDPQGYGNPDFCWLSLQDTLIWSFAGPIGAVIIINTVTSVL 2632 Query: 714 TVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTI 773 + Q+ K +L TA L L+ TW+ GL + +L Y+F I Sbjct: 2633 SAKVSCQR----KHHYYGKKGIVSLLRTAFLLLLLISATWLLGLLAVNRDALSFHYLFAI 2688 Query: 774 LNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSK-YSEFTSTTSGT 820 + LQG F+ L HC+LN++VR+ + V GG K + E ++TT T Sbjct: 2689 FSGLQGPFVLLFHCVLNQEVRKHLKG----VLGGRKLHLEDSATTRAT 2732 Score = 48.9 bits (115), Expect = 2e-05 Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 25/113 (22%) Query: 37 VNATACRCNPGFSSFSEIITTPTETCD-DINECATPSKVSCGKFSDCWNTEGSYDCVCSP 95 +N CRC PGF+ + C+ +I+ C + CG C + EG Y C C Sbjct: 1344 INGLRCRCPPGFTG---------DYCETEIDLCYSD---PCGANGRCRSREGGYTCEC-- 1389 Query: 96 GYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTL-GSYTCQCLPG 147 +E +G + C + +CK+ GTCVN L G + C C PG Sbjct: 1390 -FEDFTGEHCEVDARSGRCAN--------GVCKNGGTCVNLLIGGFHCVCPPG 1433 Score = 45.4 bits (106), Expect = 2e-04 Identities = 55/232 (23%), Positives = 79/232 (34%), Gaps = 57/232 (24%) Query: 24 RGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCW 83 RGC + + N N + + + CD + C + C S C Sbjct: 1838 RGCMQGVRMGGTPTNVATLNMN------NALKVRVKDGCDVDDPCTSSP---CPPNSRCH 1888 Query: 84 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGS---Y 140 + Y CVC GY ++ C VD C NP C++ G CV + GS Y Sbjct: 1889 DAWEDYSCVCDKGYLGIN------------C--VDACHLNP--CENMGACVRSPGSPQGY 1932 Query: 141 TCQCLPGFKFIPEDPKVCTDVNECTSG--QNPCHSSTHCLNNVG--------SYQCRCRP 190 C+C P + K+ C G NP HC + G + QC+C+ Sbjct: 1933 VCECGPSHYGPYCENKLDL---PCPRGWWGNPVCGPCHCAVSKGFDPDCNKTNGQCQCKE 1989 Query: 191 GWQPIPGSPNGPNNTVCEDVDECSSGQHQ--CDSSTVCFNTVGSYSCRCRPG 240 + + C D G H CD +T C C+PG Sbjct: 1990 NYYKLLA------QDTCLPCDCFPHGSHSRTCDMAT--------GQCACKPG 2027 Score = 42.7 bits (99), Expect = 0.001 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 20/103 (19%) Query: 91 CVCSPGYEPVSGAKTFKNESENTCQ-DVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 149 C C PG+ + + C+ ++D C +P C + G C + G YTC+C Sbjct: 1349 CRCPPGF------------TGDYCETEIDLCYSDP--CGANGRCRSREGGYTCECFE--D 1392 Query: 150 FIPEDPKVCTDVNECTSGQNPCHSSTHCLN-NVGSYQCRCRPG 191 F E +V C +G C + C+N +G + C C PG Sbjct: 1393 FTGEHCEVDARSGRCANG--VCKNGGTCVNLLIGGFHCVCPPG 1433 >gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo sapiens] Length = 2923 Score = 166 bits (420), Expect = 8e-41 Identities = 112/404 (27%), Positives = 189/404 (46%), Gaps = 37/404 (9%) Query: 412 ANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLS---HNNT----KELNSPILF 464 A AS+ ++ L Y+ R +++ + +N+ +S H++ + L+ P+ Sbjct: 2245 AVASVIIYRTLAGLLPHNYDPDKRSLRVPKRPIINTPVVSISVHDDEELLPRALDKPVTV 2304 Query: 465 AFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSD---SDRGGHWATEGCQVLGSKNG 521 F LE+ + R + +C FW S GG W+ GC+V+ Sbjct: 2305 QFRLLETEE----------------RTKPICVFWNHSILVSGTGG-WSARGCEVVFRNES 2347 Query: 522 STTCQCSHLSSFAILM---AHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGS 578 +CQC+H++SFA+LM + E L +T V L ++L LLL L+R ++ + Sbjct: 2348 HVSCQCNHMTSFAVLMDVSRRENGEILPLKTLTYVALGVTLAALLLTFFFLTLLRILRSN 2407 Query: 579 RTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY 638 + I +L L + +FL GI + C ++A LLH+ +L F W LE L LY Sbjct: 2408 QHGIRRNLTAALGLAQLVFLLGINQ--ADLPFACTVIAILLHFLYLCTFSWALLEALHLY 2465 Query: 639 FLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLG 698 + V R+ ++G+GVP I G++ + +GYG P +CWL +WSF G Sbjct: 2466 RALTEVRDVNTGPMRFYYMLGWGVPAFITGLAVGLDPEGYGNPDFCWLSIYDTLIWSFAG 2525 Query: 699 PVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLF 758 PV F + + +++ + +K L + A L LL TW+ L Sbjct: 2526 PVAFAVSMSVFLYILAA---RASCAAQRQGFEKKGPVSGLQ-PSFAVLLLLSATWLLALL 2581 Query: 759 IFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWAC 802 + +L+ Y+F NC+QG F++L + +L+K+VR+ K AC Sbjct: 2582 SVNSDTLLFHYLFATCNCIQGPFIFLSYVVLSKEVRKAL-KLAC 2624 Score = 51.2 bits (121), Expect = 4e-06 Identities = 34/112 (30%), Positives = 44/112 (39%), Gaps = 23/112 (20%) Query: 37 VNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPG 96 V CRC PGF+ + T + C CG C + EG Y C+C G Sbjct: 1269 VGGLRCRCPPGFTG--DYCETEVDLC---------YSRPCGPHGRCRSREGGYTCLCRDG 1317 Query: 97 YEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTL-GSYTCQCLPG 147 Y +G + C P +CK+ GTCVN L G + C C G Sbjct: 1318 Y---TGEHCEVSARSGRC--------TPGVCKNGGTCVNLLVGGFKCDCPSG 1358 Score = 44.3 bits (103), Expect = 5e-04 Identities = 32/109 (29%), Positives = 44/109 (40%), Gaps = 18/109 (16%) Query: 134 VNTLGSYTCQCLPGFKFIPEDPKVC-TDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGW 192 ++ +G C+C PGF C T+V+ C S PC C + G Y C CR G+ Sbjct: 1266 IHPVGGLRCRCPPGFT-----GDYCETEVDLCYS--RPCGPHGRCRSREGGYTCLCRDGY 1318 Query: 193 QPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFN-TVGSYSCRCRPG 240 G + V C+ G C + C N VG + C C G Sbjct: 1319 -------TGEHCEVSARSGRCTPG--VCKNGGTCVNLLVGGFKCDCPSG 1358 Score = 43.9 bits (102), Expect = 6e-04 Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 20/107 (18%) Query: 87 GSYDCVCSPGYEPVSGAKTFKNESENTCQ-DVDECQQNPRLCKSYGTCVNTLGSYTCQCL 145 G C C PG+ + + C+ +VD C P C +G C + G YTC C Sbjct: 1270 GGLRCRCPPGF------------TGDYCETEVDLCYSRP--CGPHGRCRSREGGYTCLCR 1315 Query: 146 PGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLN-NVGSYQCRCRPG 191 G + E +V CT G C + C+N VG ++C C G Sbjct: 1316 DG--YTGEHCEVSARSGRCTPG--VCKNGGTCVNLLVGGFKCDCPSG 1358 Score = 41.6 bits (96), Expect = 0.003 Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 19/87 (21%) Query: 158 CTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQ 217 C+ + C S NPC ++++C N+ SY C C PG+ G N T D++ C + Sbjct: 1791 CSLPDPCDS--NPCPANSYCSNDWDSYSCSCDPGYY-------GDNCTNVCDLNPC---E 1838 Query: 218 HQCDSSTVCFNTVGS---YSCRCRPGW 241 HQ +VC + Y+C C P + Sbjct: 1839 HQ----SVCTRKPSAPHGYTCECPPNY 1861 Score = 40.8 bits (94), Expect = 0.005 Identities = 52/199 (26%), Positives = 67/199 (33%), Gaps = 52/199 (26%) Query: 76 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVN 135 C S C N SY C C PGY + C +V C NP C+ C Sbjct: 1802 CPANSYCSNDWDSYSCSCDPGY------------YGDNCTNV--CDLNP--CEHQSVCTR 1845 Query: 136 TLGS---YTCQCLPGFKFIPEDPKVCTDVNE-CTSGQ------NPCHSST------HCLN 179 + YTC+C P + P T +++ C G PC+ C Sbjct: 1846 KPSAPHGYTCECPPNYL----GPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDC-- 1899 Query: 180 NVGSYQCRCRPGWQPIPGS---------PNGPNNTVCEDVD---ECSSG--QHQCDSSTV 225 N S +C C+ PGS P G + VC+ D C G QCD Sbjct: 1900 NKTSGECHCKENHYRPPGSPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCDN 1959 Query: 226 CFNTVGSYSCRCRPGWKPR 244 F V + C PR Sbjct: 1960 PFAEVTTNGCEVNYDSCPR 1978 Score = 36.6 bits (83), Expect = 0.099 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 13/69 (18%) Query: 178 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCE-DVDECSSGQHQCDSSTVCFNTVGSYSCR 236 ++ VG +CRC PG+ CE +VD C S C C + G Y+C Sbjct: 1266 IHPVGGLRCRCPPGF----------TGDYCETEVDLCYS--RPCGPHGRCRSREGGYTCL 1313 Query: 237 CRPGWKPRH 245 CR G+ H Sbjct: 1314 CRDGYTGEH 1322 >gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo sapiens] Length = 1079 Score = 159 bits (402), Expect = 1e-38 Identities = 106/322 (32%), Positives = 160/322 (49%), Gaps = 14/322 (4%) Query: 495 CAFWKSDSDRG-GHWATEGCQV-LGSKNGSTTCQCSHLSSFAILMAHYDV-EDWKLTLIT 551 C FW +G G W+ EGCQ + S + + C C HL++F++LM+ + V E+ L L+T Sbjct: 715 CVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFSVLMSPHTVPEEPALALLT 774 Query: 552 RVGLALSLFCLLLCILTFLLV------RPIQGSRTTIHLHLCICLFVGSTIFLAGIENEG 605 +VGL S+ LL+C+ + LV I R L++ CL T FL Sbjct: 775 QVGLGASILALLVCLGVYWLVWRVVVRNKISYFRHAALLNMVFCLLAADTCFLGAPFLSP 834 Query: 606 GQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQ--GQGLSTRWLCLIGYGVP 663 G C A L H+ +LA F WM + L L ++ VF + + L+GY P Sbjct: 835 GPRSPLCLAAAFLCHFLYLATFFWMLAQALVLAHQLLFVFHQLAKHRVLPLMVLLGYLCP 894 Query: 664 LLIVGVSAAIY--SKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQK 721 L + GV+ +Y Y R CWLD + G L++F+GPV II N ++ + KL + Sbjct: 895 LGLAGVTLGLYLPQGQYLREGECWLDGKGGALYTFVGPVLAIIGVNGLVLAMAMLKLLRP 954 Query: 722 FSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLF-IFDDRSLVLTYVFTILNCLQGA 780 P +K + + + + G TW GL + ++ S V Y+FTILN LQG Sbjct: 955 SLSEGPPAEKRQALLGVIKALLILTPIFGLTWGLGLATLLEEVSTVPHYIFTILNTLQGV 1014 Query: 781 FLYLLHCLLNKKVREEYRKWAC 802 F+ L CL+++K++E RK C Sbjct: 1015 FILLFGCLMDRKIQEALRKRFC 1036 >gi|223556014 G-protein coupled receptor 113 isoform 2 [Homo sapiens] Length = 997 Score = 159 bits (402), Expect = 1e-38 Identities = 106/322 (32%), Positives = 160/322 (49%), Gaps = 14/322 (4%) Query: 495 CAFWKSDSDRG-GHWATEGCQV-LGSKNGSTTCQCSHLSSFAILMAHYDV-EDWKLTLIT 551 C FW +G G W+ EGCQ + S + + C C HL++F++LM+ + V E+ L L+T Sbjct: 646 CVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFSVLMSPHTVPEEPALALLT 705 Query: 552 RVGLALSLFCLLLCILTFLLV------RPIQGSRTTIHLHLCICLFVGSTIFLAGIENEG 605 +VGL S+ LL+C+ + LV I R L++ CL T FL Sbjct: 706 QVGLGASILALLVCLGVYWLVWRVVVRNKISYFRHAALLNMVFCLLAADTCFLGAPFLSP 765 Query: 606 GQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQ--GQGLSTRWLCLIGYGVP 663 G C A L H+ +LA F WM + L L ++ VF + + L+GY P Sbjct: 766 GPRSPLCLAAAFLCHFLYLATFFWMLAQALVLAHQLLFVFHQLAKHRVLPLMVLLGYLCP 825 Query: 664 LLIVGVSAAIY--SKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQK 721 L + GV+ +Y Y R CWLD + G L++F+GPV II N ++ + KL + Sbjct: 826 LGLAGVTLGLYLPQGQYLREGECWLDGKGGALYTFVGPVLAIIGVNGLVLAMAMLKLLRP 885 Query: 722 FSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLF-IFDDRSLVLTYVFTILNCLQGA 780 P +K + + + + G TW GL + ++ S V Y+FTILN LQG Sbjct: 886 SLSEGPPAEKRQALLGVIKALLILTPIFGLTWGLGLATLLEEVSTVPHYIFTILNTLQGV 945 Query: 781 FLYLLHCLLNKKVREEYRKWAC 802 F+ L CL+++K++E RK C Sbjct: 946 FILLFGCLMDRKIQEALRKRFC 967 >gi|141802362 G-protein coupled receptor 113 isoform 3 [Homo sapiens] Length = 873 Score = 159 bits (402), Expect = 1e-38 Identities = 106/322 (32%), Positives = 160/322 (49%), Gaps = 14/322 (4%) Query: 495 CAFWKSDSDRG-GHWATEGCQV-LGSKNGSTTCQCSHLSSFAILMAHYDV-EDWKLTLIT 551 C FW +G G W+ EGCQ + S + + C C HL++F++LM+ + V E+ L L+T Sbjct: 516 CVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFSVLMSPHTVPEEPALALLT 575 Query: 552 RVGLALSLFCLLLCILTFLLV------RPIQGSRTTIHLHLCICLFVGSTIFLAGIENEG 605 +VGL S+ LL+C+ + LV I R L++ CL T FL Sbjct: 576 QVGLGASILALLVCLGVYWLVWRVVVRNKISYFRHAALLNMVFCLLAADTCFLGAPFLSP 635 Query: 606 GQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQ--GQGLSTRWLCLIGYGVP 663 G C A L H+ +LA F WM + L L ++ VF + + L+GY P Sbjct: 636 GPRSPLCLAAAFLCHFLYLATFFWMLAQALVLAHQLLFVFHQLAKHRVLPLMVLLGYLCP 695 Query: 664 LLIVGVSAAIY--SKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQK 721 L + GV+ +Y Y R CWLD + G L++F+GPV II N ++ + KL + Sbjct: 696 LGLAGVTLGLYLPQGQYLREGECWLDGKGGALYTFVGPVLAIIGVNGLVLAMAMLKLLRP 755 Query: 722 FSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLF-IFDDRSLVLTYVFTILNCLQGA 780 P +K + + + + G TW GL + ++ S V Y+FTILN LQG Sbjct: 756 SLSEGPPAEKRQALLGVIKALLILTPIFGLTWGLGLATLLEEVSTVPHYIFTILNTLQGV 815 Query: 781 FLYLLHCLLNKKVREEYRKWAC 802 F+ L CL+++K++E RK C Sbjct: 816 FILLFGCLMDRKIQEALRKRFC 837 >gi|24430141 fibrillin 1 precursor [Homo sapiens] Length = 2871 Score = 158 bits (399), Expect = 2e-38 Identities = 89/219 (40%), Positives = 107/219 (48%), Gaps = 31/219 (14%) Query: 27 ARWCPQNSSCVNATA---CRCNPGFSSFSEIITTPTET-CDDINECATPSKVSCGKFSDC 82 A CP N CVN C CNPG+ S TP C DI+EC+ + C F C Sbjct: 1163 AHLCP-NGRCVNLIGKYQCACNPGYHS------TPDRLFCVDIDECSIMNG-GCETF--C 1212 Query: 83 WNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTC 142 N+EGSY+C C PG+ + + +C D+DEC+ NP +C G C N G Y C Sbjct: 1213 TNSEGSYECSCQPGFALMP--------DQRSCTDIDECEDNPNICDG-GQCTNIPGEYRC 1263 Query: 143 QCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGP 202 C GF ED K C DVNEC N C S T C N GS+ C C G+ G Sbjct: 1264 LCYDGF-MASEDMKTCVDVNECDLNPNICLSGT-CENTKGSFICHCDMGYSGKKGK---- 1317 Query: 203 NNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241 T C D++EC G H C VC NT GS+ C C PGW Sbjct: 1318 --TGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW 1354 Score = 150 bits (379), Expect = 5e-36 Identities = 81/205 (39%), Positives = 110/205 (53%), Gaps = 25/205 (12%) Query: 37 VNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPG 96 + + CRC+ GF+ SE C DI+EC + CG+ C NT G ++C C G Sbjct: 1048 IGSFKCRCDSGFALDSE-----ERNCTDIDECRISPDL-CGR-GQCVNTPGDFECKCDEG 1100 Query: 97 YEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPK 156 YE SG KN C D+DECQ++P LC+ G C NT GSY C+C PG + P + Sbjct: 1101 YE--SGFMMMKN-----CMDIDECQRDPLLCRG-GVCHNTEGSYRCECPPGHQLSP-NIS 1151 Query: 157 VCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSG 216 C D+NEC + C + C+N +G YQC C PG+ + P+ C D+DECS Sbjct: 1152 ACIDINECELSAHLCPNG-RCVNLIGKYQCACNPGYH------STPDRLFCVDIDECSIM 1204 Query: 217 QHQCDSSTVCFNTVGSYSCRCRPGW 241 C+ T C N+ GSY C C+PG+ Sbjct: 1205 NGGCE--TFCTNSEGSYECSCQPGF 1227 Score = 147 bits (372), Expect = 3e-35 Identities = 77/217 (35%), Positives = 102/217 (47%), Gaps = 28/217 (12%) Query: 25 GCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWN 84 GC +C + C C PGF+ + +C DI+EC + G C N Sbjct: 1207 GCETFCTNSEGSYE---CSCQPGFALMPD-----QRSCTDIDECEDNPNICDG--GQCTN 1256 Query: 85 TEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQC 144 G Y C+C G+ +E TC DV+EC NP +C S GTC NT GS+ C C Sbjct: 1257 IPGEYRCLCYDGF--------MASEDMKTCVDVNECDLNPNICLS-GTCENTKGSFICHC 1307 Query: 145 LPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNN 204 G+ + CTD+NEC G + C C N GS++C C PGW + Sbjct: 1308 DMGYSG-KKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIG--------DG 1358 Query: 205 TVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241 C D+DECS+G H C C NT+GSY C C+ G+ Sbjct: 1359 IKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY 1395 Score = 130 bits (327), Expect = 5e-30 Identities = 80/234 (34%), Positives = 118/234 (50%), Gaps = 41/234 (17%) Query: 30 CPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECAT-PSKVSCGKFSDCWNT 85 C +N+ C+N C C PG+ T T C+D NEC P+ S G+ C +T Sbjct: 1818 CQRNAECINTAGSYRCDCKPGYRF------TSTGQCNDRNECQEIPNICSHGQ---CIDT 1868 Query: 86 EGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCL 145 GS+ C+C G++ N+ + C D++EC+++ C + GTC NT+GS+ C+C Sbjct: 1869 VGSFYCLCHTGFKT--------NDDQTMCLDINECERDA--CGN-GTCRNTIGSFNCRCN 1917 Query: 146 PGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNT 205 GF I C DV+EC SG + C+N VGS+QC+C G++ P+ Sbjct: 1918 HGF--ILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEV------APDGR 1969 Query: 206 VCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDM 259 C D++EC +C T C N GSY C C PG+ + N+K CED+ Sbjct: 1970 TCVDINECLLEPRKCAPGT-CQNLDGSYRCICPPGYSLQ-----NEK---CEDI 2014 Score = 124 bits (311), Expect = 4e-28 Identities = 73/214 (34%), Positives = 104/214 (48%), Gaps = 33/214 (15%) Query: 32 QNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGS 88 ++ C+N C C G+ I E C D +EC+ + CG C N G Sbjct: 2138 KHGQCINTDGSYRCECPFGY------ILAGNE-CVDTDECSVGNP--CGN-GTCKNVIGG 2187 Query: 89 YDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGF 148 ++C C G+EP TC+D++EC QNP LC CVNT GSY C+C G+ Sbjct: 2188 FECTCEEGFEP---------GPMMTCEDINECAQNPLLCAF--RCVNTYGSYECKCPVGY 2236 Query: 149 KFIPEDPKVCTDVNECTSGQNPC-HSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVC 207 + ED ++C D +EC G++ C C N +G+Y C C PG+Q P+ C Sbjct: 2237 -VLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQ------RRPDGEGC 2289 Query: 208 EDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241 D +EC + C++ C NT GSY+C C G+ Sbjct: 2290 VDENECQTKPGICENGR-CLNTRGSYTCECNDGF 2322 Score = 122 bits (305), Expect = 2e-27 Identities = 75/216 (34%), Positives = 106/216 (49%), Gaps = 33/216 (15%) Query: 28 RWCPQNSSCV---NATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWN 84 R+ QN C+ + C CN GF C D++EC K C +C N Sbjct: 457 RYLCQNGRCIPTPGSCRCECNKGFQ------LDLRGECIDVDEC---EKNPCAG-GECIN 506 Query: 85 TEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQC 144 +GSY C C GY+ + C+D+DEC QN R+C + G C+NT GS+ C C Sbjct: 507 NQGSYTCQCRAGYQ--------STLTRTECRDIDECLQNGRICNN-GRCINTDGSFHCVC 557 Query: 145 LPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNN 204 GF + D K C D++EC S +N C + C+N GS++C C+PG+Q + Sbjct: 558 NAGF-HVTRDGKNCEDMDEC-SIRNMCLNGM-CINEDGSFKCICKPGFQ------LASDG 608 Query: 205 TVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 240 C+D++EC + + C NT GSY C C PG Sbjct: 609 RYCKDINECETPGICMNGR--CVNTDGSYRCECFPG 642 Score = 119 bits (297), Expect = 2e-26 Identities = 76/217 (35%), Positives = 105/217 (48%), Gaps = 29/217 (13%) Query: 30 CPQNSSCVNATACRCN-PGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGS 88 CP S+ AT C PGF +I T DI+EC V + C N GS Sbjct: 1736 CPIPSTDEFATLCGSQRPGF-----VIDIYTGLPVDIDECREIPGVC--ENGVCINMVGS 1788 Query: 89 YDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGF 148 + C C G+ F N+ C+D+DECQ P +C+ C+NT GSY C C PG+ Sbjct: 1789 FRCECPVGF--------FYNDKLLVCEDIDECQNGP-VCQRNAECINTAGSYRCDCKPGY 1839 Query: 149 KFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCE 208 +F C D NEC N C S C++ VGS+ C C G++ + T+C Sbjct: 1840 RFTSTGQ--CNDRNECQEIPNIC-SHGQCIDTVGSFYCLCHTGFK------TNDDQTMCL 1890 Query: 209 DVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRH 245 D++EC + C + T C NT+GS++CRC G+ H Sbjct: 1891 DINECE--RDACGNGT-CRNTIGSFNCRCNHGFILSH 1924 Score = 114 bits (284), Expect = 5e-25 Identities = 73/217 (33%), Positives = 101/217 (46%), Gaps = 35/217 (16%) Query: 30 CPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTE 86 C +++ C N C C+PG+ C D++EC+ + + C + +DC NT Sbjct: 1333 CGKHAVCTNTAGSFKCSCSPGWIGDGI-------KCTDLDECSNGTHM-CSQHADCKNTM 1384 Query: 87 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 146 GSY C+C GY TC D+DEC +N LC + G C+N G Y C+C Sbjct: 1385 GSYRCLCKEGY----------TGDGFTCTDLDECSENLNLCGN-GQCLNAPGGYRCECDM 1433 Query: 147 GFKFIPE-DPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNT 205 G F+P D K C D++EC S N C T C N G ++C C G++ N + Sbjct: 1434 G--FVPSADGKACEDIDEC-SLPNICVFGT-CHNLPGLFRCECEIGYELDRSGGNCTDVN 1489 Query: 206 VCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 242 C D C SG C NT GSY C C P ++ Sbjct: 1490 ECLDPTTCISGN--------CVNTPGSYICDCPPDFE 1518 Score = 113 bits (282), Expect = 8e-25 Identities = 74/209 (35%), Positives = 100/209 (47%), Gaps = 33/209 (15%) Query: 36 CVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCV 92 CVN C+C PGF T +C D NEC + + CG C NT GS+ C Sbjct: 2500 CVNTIGGFTCKCPPGF-------TQHHTSCIDNNECTSDINL-CGSKGICQNTPGSFTCE 2551 Query: 93 CSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIP 152 C G+ +++ ++C+DVDEC+ N R +G C N +G Y C C G+ Sbjct: 2552 CQRGFS--------LDQTGSSCEDVDECEGNHRC--QHG-CQNIIGGYRCSCPQGY-LQH 2599 Query: 153 EDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDE 212 C D NEC S + C ++ C N +GSY+C C G+Q S C+D++E Sbjct: 2600 YQWNQCVDENECLSA-HICGGAS-CHNTLGSYKCMCPAGFQYEQFSGG------CQDINE 2651 Query: 213 CSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241 C S Q C S C NT G Y C C PG+ Sbjct: 2652 CGSAQAPC--SYGCSNTEGGYLCGCPPGY 2678 Score = 108 bits (269), Expect = 3e-23 Identities = 71/215 (33%), Positives = 98/215 (45%), Gaps = 33/215 (15%) Query: 31 PQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEG 87 P N C N C C G+ I+ +C D++ECAT +C C NT G Sbjct: 2454 PCNFICKNTEGSYQCSCPKGY-----ILQEDGRSCKDLDECATKQH-NCQFL--CVNTIG 2505 Query: 88 SYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPG 147 + C C PG+ + +C D +EC + LC S G C NT GS+TC+C G Sbjct: 2506 GFTCKCPPGF----------TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRG 2555 Query: 148 FKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVC 207 F + + C DV+EC G + C C N +G Y+C C G+ C Sbjct: 2556 FS-LDQTGSSCEDVDEC-EGNHRCQHG--CQNIIGGYRCSCPQGYL------QHYQWNQC 2605 Query: 208 EDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 242 D +EC S H C ++ C NT+GSY C C G++ Sbjct: 2606 VDENECLSA-HICGGAS-CHNTLGSYKCMCPAGFQ 2638 Score = 103 bits (258), Expect = 5e-22 Identities = 71/243 (29%), Positives = 99/243 (40%), Gaps = 52/243 (21%) Query: 32 QNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGS 88 Q C+N CRC G+ + T CDD+NEC TP CG C+NT G+ Sbjct: 1618 QGGKCINTFGSFQCRCPTGY-----YLNEDTRVCDDVNECETPG--ICGP-GTCYNTVGN 1669 Query: 89 YDCVCSPGYEPVSGAKTFKNESENTC-----QDVDECQQNP--RLCKSYGTCVNTLG--- 138 Y C+C P Y V+G + + C D C + K C +G Sbjct: 1670 YTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAW 1729 Query: 139 SYTCQCLPGFKFIPEDPKVCT-------------------DVNECTSGQNPCHSSTHCLN 179 + C+ P IP + T D++EC C + C+N Sbjct: 1730 NKPCEQCP----IPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGV-CIN 1784 Query: 180 NVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRP 239 VGS++C C G+ VCED+DEC +G C + C NT GSY C C+P Sbjct: 1785 MVGSFRCECPVGFF------YNDKLLVCEDIDECQNGP-VCQRNAECINTAGSYRCDCKP 1837 Query: 240 GWK 242 G++ Sbjct: 1838 GYR 1840 Score = 101 bits (251), Expect = 3e-21 Identities = 75/250 (30%), Positives = 107/250 (42%), Gaps = 75/250 (30%) Query: 32 QNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECAT-PSKVSCGKFSDCWNTEG 87 +N C+N C+CN G+ + TC DINEC P K + G C N +G Sbjct: 1943 RNGQCINTVGSFQCQCNEGYE-----VAPDGRTCVDINECLLEPRKCAPGT---CQNLDG 1994 Query: 88 SYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPG 147 SY C+C PGY + +NE C+D+DEC + P +C + GTC NT GS+ C C G Sbjct: 1995 SYRCICPPGY-------SLQNEK---CEDIDECVEEPEIC-ALGTCSNTEGSFKCLCPEG 2043 Query: 148 FKFIPEDPKVCTDV-----------NECTSGQNPCHSSTHCLNNVGSYQCRCR-PGW--- 192 F + + C D+ +C+S ++ HS C C + GW Sbjct: 2044 FS-LSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECC-------CALKGEGWGDP 2095 Query: 193 -QPIPGSPN---------------GPNNTV-----CEDVDECSSGQHQCDSSTVCFNTVG 231 + P P+ GP+++ C++ D C GQ C NT G Sbjct: 2096 CELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQ--------CINTDG 2147 Query: 232 SYSCRCRPGW 241 SY C C G+ Sbjct: 2148 SYRCECPFGY 2157 Score = 100 bits (250), Expect = 4e-21 Identities = 74/246 (30%), Positives = 106/246 (43%), Gaps = 47/246 (19%) Query: 32 QNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKV---SCGKFSDCWNT 85 +N C+N C CN GF++ + + C D E ++V C S N Sbjct: 2303 ENGRCLNTRGSYTCECNDGFTA-----SPNQDECLDNREGYCFTEVLQNMCQIGSSNRNP 2357 Query: 86 EGSYDCVCSPGYE--------PVSGAKTFKNESEN------TCQDVDECQQNPRLCKSYG 131 +C C G P G FK + D+DEC+ +C++ G Sbjct: 2358 VTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRN-G 2416 Query: 132 TCVNTLGSYTCQCLPGFKFIPEDPKV----CTDVNECTSGQNPCHSSTHCLNNVGSYQCR 187 CVN GSY C C G+ P + C D+NEC PC+ C N GSYQC Sbjct: 2417 ECVNDRGSYHCICKTGYT-----PDITGTSCVDLNECNQAPKPCNFI--CKNTEGSYQCS 2469 Query: 188 CRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHG- 246 C G+ + C+D+DEC++ QH C +C NT+G ++C+C PG+ H Sbjct: 2470 CPKGYIL------QEDGRSCKDLDECATKQHNCQF--LCVNTIGGFTCKCPPGFTQHHTS 2521 Query: 247 -IPNNQ 251 I NN+ Sbjct: 2522 CIDNNE 2527 Score = 100 bits (248), Expect = 7e-21 Identities = 72/255 (28%), Positives = 108/255 (42%), Gaps = 47/255 (18%) Query: 14 TLPGAETQDSRGC---ARWCPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINE 67 TL E +D C R C N C+N C CN GF +T + C+D++E Sbjct: 522 TLTRTECRDIDECLQNGRIC-NNGRCINTDGSFHCVCNAGFH-----VTRDGKNCEDMDE 575 Query: 68 CATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLC 127 C+ + G C N +GS+ C+C PG++ S + C+D++EC+ P +C Sbjct: 576 CSIRNMCLNGM---CINEDGSFKCICKPGFQLASDGRY--------CKDINECE-TPGIC 623 Query: 128 KSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDV---NECTSGQNPCHSSTHCLNNVGSY 184 + G CVNT GSY C+C PG + D +VC D + C G V Sbjct: 624 MN-GRCVNTDGSYRCECFPGLA-VGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKS 681 Query: 185 QCRCR-------PGWQPIPGSPNGPNNTVC----------EDVDECSSGQHQCDSSTVCF 227 +C C QP P + +C D++EC+ C + +C Sbjct: 682 ECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNG-ICE 740 Query: 228 NTVGSYSCRCRPGWK 242 N G+Y C C G++ Sbjct: 741 NLRGTYKCICNSGYE 755 Score = 99.0 bits (245), Expect = 2e-20 Identities = 57/161 (35%), Positives = 82/161 (50%), Gaps = 22/161 (13%) Query: 82 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 141 C T GS C C+ G F+ + C DVDEC++NP C G C+N GSYT Sbjct: 465 CIPTPGSCRCECNKG---------FQLDLRGECIDVDECEKNP--CAG-GECINNQGSYT 512 Query: 142 CQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNG 201 CQC G++ + C D++EC C++ C+N GS+ C C G+ N Sbjct: 513 CQCRAGYQSTLTRTE-CRDIDECLQNGRICNNG-RCINTDGSFHCVCNAGFHVTRDGKN- 569 Query: 202 PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 242 CED+DECS ++ C + +C N GS+ C C+PG++ Sbjct: 570 -----CEDMDECSI-RNMC-LNGMCINEDGSFKCICKPGFQ 603 Score = 99.0 bits (245), Expect = 2e-20 Identities = 80/267 (29%), Positives = 108/267 (40%), Gaps = 50/267 (18%) Query: 30 CPQNS-----SCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSD 81 C QN CVN C+C G+ ++ C D +EC K + Sbjct: 2210 CAQNPLLCAFRCVNTYGSYECKCPVGY-----VLREDRRMCKDEDECEEGKHDCTEKQME 2264 Query: 82 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 141 C N G+Y C+C PGY+ + C D +ECQ P +C++ G C+NT GSYT Sbjct: 2265 CKNLIGTYMCICGPGYQ--------RRPDGEGCVDENECQTKPGICEN-GRCLNTRGSYT 2315 Query: 142 CQCLPGFKFIPEDPKVCTDVNE--CTSG--QNPCHSSTHCLNNVGSYQCRC--RPGWQ-- 193 C+C GF P + C D E C + QN C + N V +C C GW Sbjct: 2316 CECNDGFTASPNQDE-CLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPH 2374 Query: 194 ----PIPGS-------PNGPN-NTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241 P G+ P+G T D+DEC C + C N GSY C C+ G+ Sbjct: 2375 CEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGE-CVNDRGSYHCICKTGY 2433 Query: 242 KPRHGIPNNQKDTVCEDMTFSTWTPPP 268 P + T C D+ P P Sbjct: 2434 TP------DITGTSCVDLNECNQAPKP 2454 Score = 98.6 bits (244), Expect = 2e-20 Identities = 72/232 (31%), Positives = 102/232 (43%), Gaps = 33/232 (14%) Query: 32 QNSSCVNATA---CRCNPGFSSFSE---IITTPTETCD---DINECATP------SKVSC 76 +N CVN C+C G + + + ETC + EC P C Sbjct: 922 KNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACC 981 Query: 77 GKFSDCWNTEGSYDCVC--SPGYE------PVSGAKTFKNESENTCQDVDECQQNPRLCK 128 W TE +C +P YE P K N + +D++EC+ P LC Sbjct: 982 CSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITN-GKPFFKDINECKMIPSLC- 1039 Query: 129 SYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRC 188 ++G C NT+GS+ C+C GF E+ + CTD++EC + C C+N G ++C+C Sbjct: 1040 THGKCRNTIGSFKCRCDSGFALDSEE-RNCTDIDECRISPDLC-GRGQCVNTPGDFECKC 1097 Query: 189 RPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 240 G++ G N C D+DEC C VC NT GSY C C PG Sbjct: 1098 DEGYE--SGFMMMKN---CMDIDECQRDPLLCRGG-VCHNTEGSYRCECPPG 1143 Score = 97.1 bits (240), Expect = 6e-20 Identities = 84/291 (28%), Positives = 116/291 (39%), Gaps = 87/291 (29%) Query: 13 LTLPGAETQDSRGCA-RWCPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINEC 68 +T G +D C+ R N C+N C C PGF S+ C DINEC Sbjct: 563 VTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASD-----GRYCKDINEC 617 Query: 69 ATPSKVSCGKFSDCWNTEGSYDCVCSP----------------------GYE------PV 100 TP G+ C NT+GSY C C P GY+ P+ Sbjct: 618 ETPGICMNGR---CVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPL 674 Query: 101 SGAKTFKNE------------------SENTCQ----------------DVDECQQNPRL 126 GA T K+E ++N+ + D++EC +P + Sbjct: 675 FGAVT-KSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDI 733 Query: 127 CKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQC 186 C + G C N G+Y C C G++ + K C D+NEC C + C N GS+ C Sbjct: 734 CPN-GICENLRGTYKCICNSGYE-VDSTGKNCVDINECVLNSLLCDNG-QCRNTPGSFVC 790 Query: 187 RCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 237 C G+ P+ CED+DEC S C + VC N+ GS+ C C Sbjct: 791 TCPKGFI------YKPDLKTCEDIDECESS--PCING-VCKNSPGSFICEC 832 Score = 97.1 bits (240), Expect = 6e-20 Identities = 77/268 (28%), Positives = 102/268 (38%), Gaps = 83/268 (30%) Query: 30 CPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSY 89 CP +S C PG +S DINECA + C N G+Y Sbjct: 699 CPAQNSAEYQALCSSGPGMTSAGS----------DINECALDPDICPNGI--CENLRGTY 746 Query: 90 DCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 149 C+C+ GYE S K C D++EC N LC + G C NT GS+ C C GF Sbjct: 747 KCICNSGYEVDSTGK--------NCVDINECVLNSLLCDN-GQCRNTPGSFVCTCPKGFI 797 Query: 150 FIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPG------------------ 191 + P D K C D++EC S +PC + C N+ GS+ C C Sbjct: 798 YKP-DLKTCEDIDECES--SPCINGV-CKNSPGSFICECSSESTLDPTKTICIETIKGTC 853 Query: 192 WQPI---------------------PGSPNGPNNTVC------------------EDVDE 212 WQ + G+ G T+C ED+DE Sbjct: 854 WQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDE 913 Query: 213 CSSGQHQCDSSTVCFNTVGSYSCRCRPG 240 C C + +C NT GS+ C+C G Sbjct: 914 CEVFPGVCKNG-LCVNTRGSFKCQCPSG 940 Score = 96.3 bits (238), Expect = 1e-19 Identities = 81/259 (31%), Positives = 104/259 (40%), Gaps = 58/259 (22%) Query: 33 NSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSY 89 N C+NA C C+ GF + + + C+DI+EC+ P+ F C N G + Sbjct: 1417 NGQCLNAPGGYRCECDMGF-----VPSADGKACEDIDECSLPNICV---FGTCHNLPGLF 1468 Query: 90 DCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 149 C C GYE + S C DV+EC +P C S G CVNT GSY C C P F+ Sbjct: 1469 RCECEIGYE--------LDRSGGNCTDVNECL-DPTTCIS-GNCVNTPGSYICDCPPDFE 1518 Query: 150 FIPEDPK-VCTDVNECTSGQNP--CHSSTHCLNNVG----SYQCRCRPG--WQP------ 194 P V T C P + T C N +G C C G W Sbjct: 1519 LNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCP 1578 Query: 195 ----------IPGS----PNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 240 PG PN P + ED+DEC C C NT GS+ CRC G Sbjct: 1579 AVNTSEYKILCPGGEGFRPN-PITVILEDIDECQELPGLCQGGK-CINTFGSFQCRCPTG 1636 Query: 241 WKPRHGIPNNQKDTVCEDM 259 + N+ VC+D+ Sbjct: 1637 YY------LNEDTRVCDDV 1649 Score = 89.0 bits (219), Expect = 2e-17 Identities = 69/229 (30%), Positives = 91/229 (39%), Gaps = 21/229 (9%) Query: 26 CARWCPQNSSCVNATACRCNPGFSSFS---EIITTPTETCDDINECATP-SKVSCGKFSD 81 C C CV C C GF+ + T P T C S + C K + Sbjct: 150 CESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTK-TL 208 Query: 82 CWNTEG---SYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLG 138 C T G + C P N CQDVDECQ P LC+ G C+NT+G Sbjct: 209 CCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQG-GNCINTVG 267 Query: 139 SYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGS 198 S+ C+C G K + E + C D++EC++ C C N V SY C+C PG+ Sbjct: 268 SFECKCPAGHK-LNEVSQKCEDIDECSTIPGICEGG-ECTNTVSSYFCKCPPGFY----- 320 Query: 199 PNGPNNTVCEDV--DECSSGQHQCDSSTVCFNTVGSYSCRCRPG--WKP 243 P+ T C DV C + S ++ C C G W P Sbjct: 321 -TSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSP 368 Score = 81.6 bits (200), Expect = 3e-15 Identities = 71/232 (30%), Positives = 94/232 (40%), Gaps = 54/232 (23%) Query: 59 TETCDDINECAT-PSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117 T +DI+EC P GK C NT GS+ C C GY + NE C DV Sbjct: 1601 TVILEDIDECQELPGLCQGGK---CINTFGSFQCRCPTGY--------YLNEDTRVCDDV 1649 Query: 118 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHC 177 +EC+ P +C GTC NT+G+YTC C P + + C D+ +N + C Sbjct: 1650 NECE-TPGICGP-GTCYNTVGNYTCICPPDYMQV-NGGNNCMDMRRSLCYRNYYADNQTC 1706 Query: 178 ----LNNVGSYQCRCR----PGWQ------PIPGSPNGPNNTVC---------------- 207 L N+ C C W PIP + T+C Sbjct: 1707 DGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFA--TLCGSQRPGFVIDIYTGLP 1764 Query: 208 EDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDM 259 D+DEC C++ VC N VGS+ C C G+ N K VCED+ Sbjct: 1765 VDIDECREIPGVCENG-VCINMVGSFRCECPVGFF------YNDKLLVCEDI 1809 Score = 77.8 bits (190), Expect = 4e-14 Identities = 70/263 (26%), Positives = 101/263 (38%), Gaps = 68/263 (25%) Query: 32 QNSSCVNATACRCNPGF---SSFSEIITTPTET------------------CDDINECAT 70 ++S C+N C+ +PG SE PT+T C+ AT Sbjct: 812 ESSPCINGV-CKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGAT 870 Query: 71 PSKVSCGKFSDCWN---TEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLC 127 C W T D +C GY + G + C+D+DEC+ P +C Sbjct: 871 LKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQ---------CEDIDECEVFPGVC 921 Query: 128 KSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVN-----------ECTSGQNPCHSSTH 176 K+ G CVNT GS+ CQC G + ++C D+ ECT H Sbjct: 922 KN-GLCVNTRGSFKCQCPSGMT-LDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDA 979 Query: 177 CLNNVGSY-------QCRCR--PGWQPIPGSPNGPNNTVCE---------DVDECSSGQH 218 C +VG+ +C R P ++ + P GP E D++EC Sbjct: 980 CCCSVGAAWGTEECEECPMRNTPEYEEL--CPRGPGFATKEITNGKPFFKDINECKMIPS 1037 Query: 219 QCDSSTVCFNTVGSYSCRCRPGW 241 C C NT+GS+ CRC G+ Sbjct: 1038 LCTHGK-CRNTIGSFKCRCDSGF 1059 Score = 75.5 bits (184), Expect = 2e-13 Identities = 66/244 (27%), Positives = 97/244 (39%), Gaps = 47/244 (19%) Query: 22 DSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSD 81 + R CA QN + C C PG+S E C+DI+EC ++ Sbjct: 1980 EPRKCAPGTCQNLD--GSYRCICPPGYS-------LQNEKCEDIDECVEEPEICA--LGT 2028 Query: 82 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQ---DVDECQQNPRLCKSYGTCVNTLG 138 C NTEGS+ C+C G+ S + ++ + C + +C S C L Sbjct: 2029 CSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALK 2088 Query: 139 SY----TCQCLP---------------GFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLN 179 C+ P G P+D V D++EC H C+N Sbjct: 2089 GEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAV--DMDECKEPDVCKHGQ--CIN 2144 Query: 180 NVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRP 239 GSY+C C G+ + G+ C D DECS G + C + T C N +G + C C Sbjct: 2145 TDGSYRCECPFGYI-LAGNE-------CVDTDECSVG-NPCGNGT-CKNVIGGFECTCEE 2194 Query: 240 GWKP 243 G++P Sbjct: 2195 GFEP 2198 Score = 68.2 bits (165), Expect = 3e-11 Identities = 62/235 (26%), Positives = 88/235 (37%), Gaps = 33/235 (14%) Query: 16 PGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVS 75 P ++ + C C SC + C C G+ C + C P++ + Sbjct: 109 PSCGSRSIQHCNIRCMNGGSCSD-DHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCA 167 Query: 76 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTC-- 133 C T G C Y F S CQ Q + +C C Sbjct: 168 C--------TYGFTGPQCERDYRT---GPCFTVISNQMCQG----QLSGIVCTKTLCCAT 212 Query: 134 VNTLGSYTCQCLPGFK------FIPE-DPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQC 186 V + C+ P FIP C DV+EC + C +C+N VGS++C Sbjct: 213 VGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGG-NCINTVGSFEC 271 Query: 187 RCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241 +C G + S CED+DECS+ C+ C NTV SY C+C PG+ Sbjct: 272 KCPAGHKLNEVSQK------CEDIDECSTIPGICEGGE-CTNTVSSYFCKCPPGF 319 Score = 65.5 bits (158), Expect = 2e-10 Identities = 58/207 (28%), Positives = 78/207 (37%), Gaps = 38/207 (18%) Query: 62 CDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTC---QDVD 118 C+DI+EC V K C NT GS+ C C G + + + TC + + Sbjct: 908 CEDIDECEVFPGVC--KNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDE 965 Query: 119 EC-------QQNPRLCKSYGTCVNTLGSYTCQCL------------PGF--KFIPEDPKV 157 EC + C S G T C PGF K I Sbjct: 966 ECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPF 1025 Query: 158 CTDVNECTSGQNPCHSSTH--CLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSS 215 D+NEC + C TH C N +GS++CRC G+ N C D+DEC Sbjct: 1026 FKDINECKMIPSLC---THGKCRNTIGSFKCRCDSGFALDSEERN------CTDIDECRI 1076 Query: 216 GQHQCDSSTVCFNTVGSYSCRCRPGWK 242 C C NT G + C+C G++ Sbjct: 1077 SPDLCGRGQ-CVNTPGDFECKCDEGYE 1102 Score = 55.1 bits (131), Expect = 3e-07 Identities = 80/303 (26%), Positives = 107/303 (35%), Gaps = 72/303 (23%) Query: 3 GRVFLAFCV--WLTLPGAETQDSRGCARWCPQNSSCVNATACR--CNPGFSSFSEIITTP 58 G + A+C W TLPG + C+ CR C GF S + T P Sbjct: 60 GSRYNAYCCPGWKTLPGG---------------NQCI-VPICRHSCGDGFCSRPNMCTCP 103 Query: 59 TETCDDINECATPSKVSCGKFSDCWNTEGSYD--CVCSPGYEPVSGAKTFKNESENTCQD 116 + C + S C C N D C+C GY G + E+ C + Sbjct: 104 SGQIAP--SCGSRSIQHCN--IRCMNGGSCSDDHCLCQKGY---IGTHCGQPVCESGCLN 156 Query: 117 VDECQQNPRLCKSYG-------------TCVNTLGSYTCQC-LPGFKFIPEDPKVCTDVN 162 C R +YG C + + CQ L G VCT Sbjct: 157 GGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGI--------VCTKTL 208 Query: 163 EC-TSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCD 221 C T G+ H C + CR G+ IP G C+DVDEC + C Sbjct: 209 CCATVGRAWGHPCEMC----PAQPHPCRRGF--IPNIRTG----ACQDVDECQAIPGLCQ 258 Query: 222 SSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTP---PPGVHSQTLSRF 278 C NTVGS+ C+C G K N+ CED+ + P G + T+S + Sbjct: 259 GGN-CINTVGSFECKCPAGHK------LNEVSQKCEDIDECSTIPGICEGGECTNTVSSY 311 Query: 279 FDK 281 F K Sbjct: 312 FCK 314 >gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo sapiens] Length = 3312 Score = 158 bits (399), Expect = 2e-38 Identities = 109/389 (28%), Positives = 183/389 (47%), Gaps = 40/389 (10%) Query: 430 YESSIRGVQLRRLSAVNS------IFLSHNNTKE-LNSPILFAFSHLESSDGEAGRDPPA 482 +++ RG +L + +NS +F N + L SPI F L++++ Sbjct: 2424 FQAERRGARLPQNPVMNSPVVSVAVFHGRNFLRGILESPISLEFRLLQTAN--------- 2474 Query: 483 KDVMPGPRQELLCAFWKSD--SDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHY 540 R + +C W +++ G W C+++ C+CS +F +LM Sbjct: 2475 -------RSKAICVQWDPPGLAEQHGVWTARDCELVHRNGSHARCRCSRTGTFGVLMDAS 2527 Query: 541 DVEDWK-----LTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGST 595 E + L + T V +A+S+ L+L L +R ++ + IH ++ L V Sbjct: 2528 PRERLEGDLELLAVFTHVVVAVSVAALVLTAAILLSLRSLKSNVRGIHANVAAALGVAEL 2587 Query: 596 IFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWL 655 +FL GI Q L C VA LLHY FL+ F W+ ++GL LY + V + R+ Sbjct: 2588 LFLLGIHRTHNQ--LVCTAVAILLHYFFLSTFAWLFVQGLHLYRMQVEPRNVDRGAMRFY 2645 Query: 656 CLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTV 715 +G+GVP +++G++ + +GYG P +CW+ + +WSF GPV +I+ N +F Sbjct: 2646 HALGWGVPAVLLGLAVGLDPEGYGNPDFCWISVHEPLIWSFAGPVVLVIVMNGTMF---- 2701 Query: 716 WKLTQKFSEINPDMKKLKKARALTI-TAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTIL 774 L + + ++ KK ALT+ ++ L L+ +W+FGL + L Y+ L Sbjct: 2702 --LLAARTSCSTGQREAKKTSALTLRSSFLLLLLVSASWLFGLLAVNHSILAFHYLHAGL 2759 Query: 775 NCLQGAFLYLLHCLLNKKVREEYRKWACL 803 LQG + LL C+LN R + ACL Sbjct: 2760 CGLQGLAVLLLFCVLNADARAAWMP-ACL 2787 Score = 48.5 bits (114), Expect = 3e-05 Identities = 33/114 (28%), Positives = 51/114 (44%), Gaps = 25/114 (21%) Query: 91 CVCSPGYEPVSGAKTFKNESENTCQ-DVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 149 C C PG+ + + C+ ++D C NP C++ G C G YTC C P + Sbjct: 1421 CRCPPGF------------TGDFCETELDLCYSNP--CRNGGACARREGGYTCVCRP--R 1464 Query: 150 FIPEDPKVCTDVNECTSGQNPCHSSTHCLNNV-GSYQCRCRPGWQPIPGSPNGP 202 F ED ++ T+ C G C + C + G ++C+C P G+ GP Sbjct: 1465 FTGEDCELDTEAGRCVPG--VCRNGGTCTDAPNGGFRCQC-----PAGGAFEGP 1511 Score = 43.1 bits (100), Expect = 0.001 Identities = 31/110 (28%), Positives = 44/110 (40%), Gaps = 23/110 (20%) Query: 42 CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 101 CRC PGF+ + T + C + P C C EG Y CVC P + Sbjct: 1421 CRCPPGFTG--DFCETELDLC-----YSNP----CRNGGACARREGGYTCVCRPRF---- 1465 Query: 102 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNT-LGSYTCQCLPGFKF 150 E+ D + + P +C++ GTC + G + CQC G F Sbjct: 1466 -------TGEDCELDTEAGRCVPGVCRNGGTCTDAPNGGFRCQCPAGGAF 1508 Score = 41.6 bits (96), Expect = 0.003 Identities = 48/195 (24%), Positives = 69/195 (35%), Gaps = 53/195 (27%) Query: 62 CDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQ 121 C N CA+ C +DC + ++ C C PGY C VD C Sbjct: 1944 CVVTNACASGP---CPPHADCRDLWQTFSCTCQPGYYGPG------------C--VDACL 1986 Query: 122 QNPRLCKSYGTCVNTLGS---YTCQCLPGF-------KFIPEDPKVCTDVNECTSGQNPC 171 NP C++ G+C + G+ YTC C+ G+ + + P+ C PC Sbjct: 1987 LNP--CQNQGSCRHLPGAPHGYTCDCVGGYFGHHCEHRMDQQCPRGWWGSPTC----GPC 2040 Query: 172 HSSTH------CLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTV 225 + H C N + QC C+ P G ++ + D S C Sbjct: 2041 NCDVHKGFDPNC--NKTNGQCHCK----EFHYRPRGSDSCLPCDCYPVGSTSRSC----- 2089 Query: 226 CFNTVGSYSCRCRPG 240 S C CRPG Sbjct: 2090 ---APHSGQCPCRPG 2101 Score = 38.9 bits (89), Expect = 0.020 Identities = 28/109 (25%), Positives = 43/109 (39%), Gaps = 18/109 (16%) Query: 134 VNTLGSYTCQCLPGFKFIPEDPKVC-TDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGW 192 + + C+C PGF C T+++ C S NPC + C G Y C CRP + Sbjct: 1413 IQPIAGLRCRCPPGFT-----GDFCETELDLCYS--NPCRNGGACARREGGYTCVCRPRF 1465 Query: 193 QPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTV-GSYSCRCRPG 240 G + + + C G C + C + G + C+C G Sbjct: 1466 -------TGEDCELDTEAGRCVPG--VCRNGGTCTDAPNGGFRCQCPAG 1505 >gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens] Length = 995 Score = 154 bits (390), Expect = 2e-37 Identities = 146/584 (25%), Positives = 248/584 (42%), Gaps = 72/584 (12%) Query: 254 TVCEDMTFSTWTPPPG----VHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN-VIKLVDEL 308 TV +T + PP V++ ++S ++V + + S E + +I V L Sbjct: 327 TVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLGSLEPNLAGEMINQVSRL 386 Query: 309 MEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERG 368 + +P D+ LAP +A +LL ++DI L S T IS ++ L L + Sbjct: 387 LHSPPDM--LAP-----LAQRLLKVVDDIGLQLNFSN-----TTISLTSPSLALAVIRVN 434 Query: 369 DKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEE 428 + A+ N V+ + P ++ I ++ L + L S+ Q E Sbjct: 435 ASSFNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFFE 494 Query: 429 ----IYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKD 484 + S+ + L +S V S +++ + L + H+ S E Sbjct: 495 TPALFQDPSLENLSL--ISYVISSSVANLTVRNLTRNVTVTLKHINPSQDEL-------- 544 Query: 485 VMPGPRQELLCAFWKSDSDRG-GHWATEGCQVLGSKNGSTTCQCSHLSSFAILM-----A 538 + C FW + G G W+ GC V + T C CSHL+SF +L+ + Sbjct: 545 -------TVRCVFWDLGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTS 597 Query: 539 HYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTT-IHLHLCICLFVGSTIF 597 + LT IT +G LS L + ++T++ I+ + I + LC L + + +F Sbjct: 598 VLPAQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVF 657 Query: 598 LAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLS-TRWLC 656 L ++ C VA LHY L +F WM LE +Y +V+VF C Sbjct: 658 LLDSWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFC 717 Query: 657 LIGYGVPLLIVGVSAAIYSKGYGRPRY-----------CWLDFEQGFLWSFLGPVTFIIL 705 ++G+GVP ++V + I YG Y CW++ F + +G I L Sbjct: 718 IVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFL 777 Query: 706 CNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQL-------FLLGCTWVFGLF 758 N +F+ + +L + +KK K+ A T+I L FLLG TW F F Sbjct: 778 LNVSMFIVVLVQLCR--------IKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFF 829 Query: 759 IFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWAC 802 + ++ Y+F I N LQG F+++ +C+ + VR+++R++ C Sbjct: 830 AWGPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWRRYLC 873 >gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens] Length = 1003 Score = 154 bits (390), Expect = 2e-37 Identities = 146/584 (25%), Positives = 248/584 (42%), Gaps = 72/584 (12%) Query: 254 TVCEDMTFSTWTPPPG----VHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN-VIKLVDEL 308 TV +T + PP V++ ++S ++V + + S E + +I V L Sbjct: 335 TVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLGSLEPNLAGEMINQVSRL 394 Query: 309 MEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERG 368 + +P D+ LAP +A +LL ++DI L S T IS ++ L L + Sbjct: 395 LHSPPDM--LAP-----LAQRLLKVVDDIGLQLNFSN-----TTISLTSPSLALAVIRVN 442 Query: 369 DKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEE 428 + A+ N V+ + P ++ I ++ L + L S+ Q E Sbjct: 443 ASSFNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFFE 502 Query: 429 ----IYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKD 484 + S+ + L +S V S +++ + L + H+ S E Sbjct: 503 TPALFQDPSLENLSL--ISYVISSSVANLTVRNLTRNVTVTLKHINPSQDEL-------- 552 Query: 485 VMPGPRQELLCAFWKSDSDRG-GHWATEGCQVLGSKNGSTTCQCSHLSSFAILM-----A 538 + C FW + G G W+ GC V + T C CSHL+SF +L+ + Sbjct: 553 -------TVRCVFWDLGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTS 605 Query: 539 HYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTT-IHLHLCICLFVGSTIF 597 + LT IT +G LS L + ++T++ I+ + I + LC L + + +F Sbjct: 606 VLPAQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVF 665 Query: 598 LAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLS-TRWLC 656 L ++ C VA LHY L +F WM LE +Y +V+VF C Sbjct: 666 LLDSWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFC 725 Query: 657 LIGYGVPLLIVGVSAAIYSKGYGRPRY-----------CWLDFEQGFLWSFLGPVTFIIL 705 ++G+GVP ++V + I YG Y CW++ F + +G I L Sbjct: 726 IVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFL 785 Query: 706 CNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQL-------FLLGCTWVFGLF 758 N +F+ + +L + +KK K+ A T+I L FLLG TW F F Sbjct: 786 LNVSMFIVVLVQLCR--------IKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFF 837 Query: 759 IFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWAC 802 + ++ Y+F I N LQG F+++ +C+ + VR+++R++ C Sbjct: 838 AWGPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWRRYLC 881 >gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens] Length = 1017 Score = 154 bits (390), Expect = 2e-37 Identities = 146/584 (25%), Positives = 248/584 (42%), Gaps = 72/584 (12%) Query: 254 TVCEDMTFSTWTPPPG----VHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN-VIKLVDEL 308 TV +T + PP V++ ++S ++V + + S E + +I V L Sbjct: 349 TVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLGSLEPNLAGEMINQVSRL 408 Query: 309 MEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERG 368 + +P D+ LAP +A +LL ++DI L S T IS ++ L L + Sbjct: 409 LHSPPDM--LAP-----LAQRLLKVVDDIGLQLNFSN-----TTISLTSPSLALAVIRVN 456 Query: 369 DKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEE 428 + A+ N V+ + P ++ I ++ L + L S+ Q E Sbjct: 457 ASSFNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFFE 516 Query: 429 ----IYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKD 484 + S+ + L +S V S +++ + L + H+ S E Sbjct: 517 TPALFQDPSLENLSL--ISYVISSSVANLTVRNLTRNVTVTLKHINPSQDEL-------- 566 Query: 485 VMPGPRQELLCAFWKSDSDRG-GHWATEGCQVLGSKNGSTTCQCSHLSSFAILM-----A 538 + C FW + G G W+ GC V + T C CSHL+SF +L+ + Sbjct: 567 -------TVRCVFWDLGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTS 619 Query: 539 HYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTT-IHLHLCICLFVGSTIF 597 + LT IT +G LS L + ++T++ I+ + I + LC L + + +F Sbjct: 620 VLPAQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVF 679 Query: 598 LAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLS-TRWLC 656 L ++ C VA LHY L +F WM LE +Y +V+VF C Sbjct: 680 LLDSWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFC 739 Query: 657 LIGYGVPLLIVGVSAAIYSKGYGRPRY-----------CWLDFEQGFLWSFLGPVTFIIL 705 ++G+GVP ++V + I YG Y CW++ F + +G I L Sbjct: 740 IVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFL 799 Query: 706 CNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQL-------FLLGCTWVFGLF 758 N +F+ + +L + +KK K+ A T+I L FLLG TW F F Sbjct: 800 LNVSMFIVVLVQLCR--------IKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFF 851 Query: 759 IFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWAC 802 + ++ Y+F I N LQG F+++ +C+ + VR+++R++ C Sbjct: 852 AWGPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWRRYLC 895 >gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens] Length = 1014 Score = 154 bits (390), Expect = 2e-37 Identities = 146/584 (25%), Positives = 248/584 (42%), Gaps = 72/584 (12%) Query: 254 TVCEDMTFSTWTPPPG----VHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN-VIKLVDEL 308 TV +T + PP V++ ++S ++V + + S E + +I V L Sbjct: 346 TVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLGSLEPNLAGEMINQVSRL 405 Query: 309 MEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERG 368 + +P D+ LAP +A +LL ++DI L S T IS ++ L L + Sbjct: 406 LHSPPDM--LAP-----LAQRLLKVVDDIGLQLNFSN-----TTISLTSPSLALAVIRVN 453 Query: 369 DKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEE 428 + A+ N V+ + P ++ I ++ L + L S+ Q E Sbjct: 454 ASSFNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFFE 513 Query: 429 ----IYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKD 484 + S+ + L +S V S +++ + L + H+ S E Sbjct: 514 TPALFQDPSLENLSL--ISYVISSSVANLTVRNLTRNVTVTLKHINPSQDEL-------- 563 Query: 485 VMPGPRQELLCAFWKSDSDRG-GHWATEGCQVLGSKNGSTTCQCSHLSSFAILM-----A 538 + C FW + G G W+ GC V + T C CSHL+SF +L+ + Sbjct: 564 -------TVRCVFWDLGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTS 616 Query: 539 HYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTT-IHLHLCICLFVGSTIF 597 + LT IT +G LS L + ++T++ I+ + I + LC L + + +F Sbjct: 617 VLPAQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVF 676 Query: 598 LAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLS-TRWLC 656 L ++ C VA LHY L +F WM LE +Y +V+VF C Sbjct: 677 LLDSWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFC 736 Query: 657 LIGYGVPLLIVGVSAAIYSKGYGRPRY-----------CWLDFEQGFLWSFLGPVTFIIL 705 ++G+GVP ++V + I YG Y CW++ F + +G I L Sbjct: 737 IVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFL 796 Query: 706 CNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQL-------FLLGCTWVFGLF 758 N +F+ + +L + +KK K+ A T+I L FLLG TW F F Sbjct: 797 LNVSMFIVVLVQLCR--------IKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFF 848 Query: 759 IFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWAC 802 + ++ Y+F I N LQG F+++ +C+ + VR+++R++ C Sbjct: 849 AWGPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWRRYLC 892 >gi|56237021 fibrillin 3 precursor [Homo sapiens] Length = 2809 Score = 153 bits (387), Expect = 6e-37 Identities = 92/235 (39%), Positives = 112/235 (47%), Gaps = 32/235 (13%) Query: 13 LTLPGAETQDSRGCAR---WCPQNSSCVN---ATACRCNPGFSSFSEIITTPTETCDDIN 66 LT G +D C+ CP + CVN A C C+ GF S T + C DIN Sbjct: 1104 LTAKGTACEDIDECSLSDGLCP-HGQCVNVIGAFQCSCHAGFQS-----TPDRQGCVDIN 1157 Query: 67 ECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRL 126 EC + G C NTEGSY C C GY + + C DVDEC++NPR+ Sbjct: 1158 ECRVQNG---GCDVHCINTEGSYRCSCGQGYSLMPDGRA--------CADVDECEENPRV 1206 Query: 127 CKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQC 186 C G C N G + C C GF P D + C DV+EC + C C N GS+ C Sbjct: 1207 CDQ-GHCTNMPGGHRCLCYDGFMATP-DMRTCVDVDECDLNPHICLHGD-CENTKGSFVC 1263 Query: 187 RCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241 C+ G+ G+ T C DVDEC G H CDS C N GS+SCRC PGW Sbjct: 1264 HCQLGYMVRKGA------TGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGW 1312 Score = 130 bits (326), Expect = 7e-30 Identities = 84/240 (35%), Positives = 111/240 (46%), Gaps = 32/240 (13%) Query: 13 LTLPGAETQDSRGC---ARW------CPQNSSCVNATACRCNPGFSSFSEIITTPTETCD 63 +TLPG D C A W CP S A+ C GF+S + P Sbjct: 928 VTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYK-- 985 Query: 64 DINECAT-PSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQ 122 D+NEC P + G C NT GS+ C C+ G+ + E C D+DEC+ Sbjct: 986 DVNECKVFPGLCTHGT---CRNTVGSFHCACAGGFA--------LDAQERNCTDIDECRI 1034 Query: 123 NPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVG 182 +P LC GTCVNT GS+ C+C PG++ K C DV+EC C T C N G Sbjct: 1035 SPDLC-GQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGT-CTNTDG 1092 Query: 183 SYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 242 SY+C+C PG + T CED+DECS C C N +G++ C C G++ Sbjct: 1093 SYKCQCPPGHELT------AKGTACEDIDECSLSDGLCPHGQ-CVNVIGAFQCSCHAGFQ 1145 Score = 129 bits (325), Expect = 9e-30 Identities = 82/262 (31%), Positives = 111/262 (42%), Gaps = 58/262 (22%) Query: 35 SCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDC 91 +CVN C C PG+ S ++ + C D++ECA + G C NT+GSY C Sbjct: 1043 TCVNTPGSFECECFPGYESGFMLM----KNCMDVDECARDPLLCRG--GTCTNTDGSYKC 1096 Query: 92 VCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFI 151 C PG+E + C+D+DEC + LC +G CVN +G++ C C GF+ Sbjct: 1097 QCPPGHELTAKG--------TACEDIDECSLSDGLCP-HGQCVNVIGAFQCSCHAGFQST 1147 Query: 152 PEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGS------------- 198 P D + C D+NEC C HC+N GSY+C C G+ +P Sbjct: 1148 P-DRQGCVDINECRVQNGGC--DVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENP 1204 Query: 199 -----------PNG------------PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSC 235 P G P+ C DVDEC H C C NT GS+ C Sbjct: 1205 RVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGD-CENTKGSFVC 1263 Query: 236 RCRPGWKPRHGIPNNQKDTVCE 257 C+ G+ R G CE Sbjct: 1264 HCQLGYMVRKGATGCSDVDECE 1285 Score = 125 bits (313), Expect = 2e-28 Identities = 77/231 (33%), Positives = 111/231 (48%), Gaps = 34/231 (14%) Query: 14 TLPGAETQDSRGCARWCPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECAT 70 T G + + R A C + C+N+ C C G++ TC D++EC+ Sbjct: 2358 TAEGRDVDECRMLAHLCA-HGECINSLGSFRCHCQAGYTP-----DATATTCLDMDECSQ 2411 Query: 71 PSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSY 130 K C C NT+GS+ C C GY E TC+D+DEC C+ Sbjct: 2412 VPK-PCTFL--CKNTKGSFLCSCPRGY--------LLEEDGRTCKDLDECTSRQHNCQFL 2460 Query: 131 GTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 190 CVNT+G++TC+C PGF + + C D +EC++ PC + HC N GS++C C Sbjct: 2461 --CVNTVGAFTCRCPPGFT---QHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQ 2515 Query: 191 GWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241 G+ + S +G CEDV+EC G H+C C N +G Y C C G+ Sbjct: 2516 GF-TLVSSGHG-----CEDVNEC-DGPHRCQHG--CQNQLGGYRCSCPQGF 2557 Score = 124 bits (310), Expect = 5e-28 Identities = 82/246 (33%), Positives = 111/246 (45%), Gaps = 35/246 (14%) Query: 30 CPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECAT-PSKVSCGKFSDCWNT 85 C QN+ C+N C+C G+ +P C NEC P+ S G DC +T Sbjct: 1774 CQQNADCINIPGSYRCKCTRGYK------LSPGGACVGRNECREIPNVCSHG---DCMDT 1824 Query: 86 EGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCL 145 EGSY C+C G++ + + C D+DEC + P C + GTC N +GSY C C Sbjct: 1825 EGSYMCLCHRGFQA--------SADQTLCMDIDECDRQP--CGN-GTCKNIIGSYNCLCF 1873 Query: 146 PGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNT 205 PGF C D +ECT+ HCLN GS+ C C+ G++ N Sbjct: 1874 PGFVVTHNGD--CVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKN----- 1926 Query: 206 VCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPR--HGIPNNQKDTVCEDMTFST 263 C D +EC S C T C N GS+ C C PG++ + H I ++ F T Sbjct: 1927 -CVDTNECLSLAGTCLPGT-CQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGT 1984 Query: 264 WTPPPG 269 T PG Sbjct: 1985 CTNSPG 1990 Score = 120 bits (300), Expect = 7e-27 Identities = 72/213 (33%), Positives = 106/213 (49%), Gaps = 30/213 (14%) Query: 33 NSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSY 89 N C+N C C GF+ S ++ C+D++EC + C + +DC N GSY Sbjct: 1734 NGICINQIGSFRCECPAGFNYNSILLA-----CEDVDECGSRES-PCQQNADCINIPGSY 1787 Query: 90 DCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 149 C C+ GY+ G C +EC++ P +C S+G C++T GSY C C GF+ Sbjct: 1788 RCKCTRGYKLSPGG---------ACVGRNECREIPNVC-SHGDCMDTEGSYMCLCHRGFQ 1837 Query: 150 FIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCED 209 D +C D++EC + PC + T C N +GSY C C PG+ +N C D Sbjct: 1838 -ASADQTLCMDIDECD--RQPCGNGT-CKNIIGSYNCLCFPGFVVT-------HNGDCVD 1886 Query: 210 VDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 242 DEC++ Q C NT GS+ C C+ G++ Sbjct: 1887 FDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFE 1919 Score = 113 bits (283), Expect = 6e-25 Identities = 73/211 (34%), Positives = 101/211 (47%), Gaps = 33/211 (15%) Query: 30 CPQNSSCVN---ATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTE 86 C ++SC+N + +CRC PG+ C D++EC + C DC N Sbjct: 1291 CDSHASCLNIPGSFSCRCLPGWVGDGF-------ECHDLDECVSQEH-RCSPRGDCLNVP 1342 Query: 87 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 146 GSY C C G+ +G F C+D DEC +N LC + G C+N G Y C+C Sbjct: 1343 GSYRCTCRQGF---AGDGFF-------CEDRDECAENVDLCDN-GQCLNAPGGYRCECEM 1391 Query: 147 GFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTV 206 GF ED + C DV+EC G N C + C N G ++C C G++ G N Sbjct: 1392 GFD-PTEDHRACQDVDECAQG-NLCAFGS-CENLPGMFRCICNGGYELDRGGGN------ 1442 Query: 207 CEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 237 C D++EC+ + + VC NT GSY C C Sbjct: 1443 CTDINECADPVNCING--VCINTPGSYLCSC 1471 Score = 110 bits (276), Expect = 4e-24 Identities = 69/218 (31%), Positives = 96/218 (44%), Gaps = 29/218 (13%) Query: 30 CPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSY 89 CPQ S C G + P ++ +D+NECA V C NT+GS+ Sbjct: 2056 CPQEGSAAFQELCPFGHG------AVPGPDDSREDVNECAENPGVCTNGV--CVNTDGSF 2107 Query: 90 DCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 149 C C GY + + C D DEC GTC N +G + C C GF+ Sbjct: 2108 RCECPFGYS--------LDFTGINCVDTDECSVGHPC--GQGTCTNVIGGFECACADGFE 2157 Query: 150 FIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCED 209 P C D++EC+ NP + C N GSY C C G+ + +C D Sbjct: 2158 --PGLMMTCEDIDECSL--NPLLCAFRCHNTEGSYLCTCPAGYTL------REDGAMCRD 2207 Query: 210 VDECSSGQHQCDSSTV-CFNTVGSYSCRCRPGWKPRHG 246 VDEC+ GQ C + + C N +G+++C C PG +P G Sbjct: 2208 VDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPG 2245 Score = 110 bits (274), Expect = 7e-24 Identities = 70/199 (35%), Positives = 92/199 (46%), Gaps = 30/199 (15%) Query: 42 CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 101 C CN G++ C D++EC + S DC N G+Y C C PG++ Sbjct: 433 CECNVGYTQ------DVRGECIDVDECTS----SPCHHGDCVNIPGTYHCRCYPGFQATP 482 Query: 102 GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDV 161 + C DVDEC + LC G CVNT GS+ C C GF+ P D K C D Sbjct: 483 --------TRQACVDVDECIVSGGLCH-LGRCVNTEGSFQCVCNAGFELSP-DGKNCVDH 532 Query: 162 NECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCD 221 NEC + C + CLN GS+ C C+PG+ PG C D+DEC + + Sbjct: 533 NECATS-TMCVNGV-CLNEDGSFSCLCKPGFLLAPG------GHYCMDIDECQTPGICVN 584 Query: 222 SSTVCFNTVGSYSCRCRPG 240 C NT GS+ C+C G Sbjct: 585 GH--CTNTEGSFRCQCLGG 601 Score = 107 bits (267), Expect = 5e-23 Identities = 82/289 (28%), Positives = 110/289 (38%), Gaps = 79/289 (27%) Query: 22 DSRGCA---------RWCPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECA 69 D R CA R C Q C N C C GF + T TC D++EC Sbjct: 1190 DGRACADVDECEENPRVCDQGH-CTNMPGGHRCLCYDGFMA-----TPDMRTCVDVDECD 1243 Query: 70 TPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKS 129 + DC NT+GS+ C C GY GA C DVDEC+ C S Sbjct: 1244 LNPHICL--HGDCENTKGSFVCHCQLGYMVRKGA--------TGCSDVDECEVGGHNCDS 1293 Query: 130 YGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCH----------------- 172 + +C+N GS++C+CLPG+ D C D++EC S ++ C Sbjct: 1294 HASCLNIPGSFSCRCLPGWV---GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCR 1350 Query: 173 -----------------------SSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCED 209 + CLN G Y+C C G+ P ++ C+D Sbjct: 1351 QGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPT------EDHRACQD 1404 Query: 210 VDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCED 258 VDEC+ G S C N G + C C G++ G N C D Sbjct: 1405 VDECAQGNLCAFGS--CENLPGMFRCICNGGYELDRGGGNCTDINECAD 1451 Score = 107 bits (266), Expect = 6e-23 Identities = 77/204 (37%), Positives = 92/204 (45%), Gaps = 41/204 (20%) Query: 16 PGAETQDSRGCA----------RWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDI 65 PG T+ CA + CP S C G ITT DI Sbjct: 634 PGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLG-------ITTDGR---DI 683 Query: 66 NECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPR 125 NECA +V C N GSY CVC+ GYE + K C DVDEC N Sbjct: 684 NECALDPEVCANGV--CENLRGSYRCVCNLGYEAGASGKD--------CTDVDECALNSL 733 Query: 126 LCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQ 185 LC + G C N+ GSY+C C PGF F +D ++C DV+EC S +PC S C N GSY Sbjct: 734 LCDN-GWCQNSPGSYSCSCPPGFHFW-QDTEICKDVDECLS--SPCVSGV-CRNLAGSYT 788 Query: 186 CRCRPGWQPIPGSPNGPNNTVCED 209 C+C PGS P+ T C D Sbjct: 789 CKCG------PGSRLDPSGTFCLD 806 Score = 107 bits (266), Expect = 6e-23 Identities = 73/212 (34%), Positives = 97/212 (45%), Gaps = 38/212 (17%) Query: 36 CVN---ATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCV 92 CVN A CRC PGF T + C D +EC+ CG C NT GS+ C Sbjct: 2461 CVNTVGAFTCRCPPGF-------TQHHQACFDNDECSAQPG-PCGAHGHCHNTPGSFRCE 2512 Query: 93 CSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIP 152 C G+ VS S + C+DV+EC P C+ C N LG Y C C GF Sbjct: 2513 CHQGFTLVS--------SGHGCEDVNECD-GPHRCQH--GCQNQLGGYRCSCPQGFTQHS 2561 Query: 153 EDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGW---QPIPGSPNGPNNTVCED 209 + + C D NEC C S++ C N +G ++C C G+ Q + G C++ Sbjct: 2562 QWAQ-CVDENECALSPPTCGSAS-CRNTLGGFRCVCPSGFDFDQALGG---------CQE 2610 Query: 210 VDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241 VDEC+ + C S C NT G + C C G+ Sbjct: 2611 VDECAGRRGPCSYS--CANTPGGFLCGCPQGY 2640 Score = 106 bits (264), Expect = 1e-22 Identities = 74/235 (31%), Positives = 107/235 (45%), Gaps = 41/235 (17%) Query: 33 NSSCVNATA---CRCNPGFSSFSEIITTPTET-CDDINE---CATPSKVSCGKFSDCWNT 85 N CVN C C+ GF +PT T C DI + A + C S Sbjct: 2265 NGRCVNTAGSFRCDCDEGFQP------SPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEA 2318 Query: 86 EGSYDCVCSPGYE--------PVSGAKTFK----NESENTCQ--DVDECQQNPRLCKSYG 131 +C C G P+ G ++ + S T + DVDEC+ LC ++G Sbjct: 2319 VTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLC-AHG 2377 Query: 132 TCVNTLGSYTCQCLPGFKFIPE-DPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 190 C+N+LGS+ C C G+ P+ C D++EC+ PC + C N GS+ C C Sbjct: 2378 ECINSLGSFRCHCQAGYT--PDATATTCLDMDECSQVPKPC--TFLCKNTKGSFLCSCPR 2433 Query: 191 GWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRH 245 G+ + C+D+DEC+S QH C +C NTVG+++CRC PG+ H Sbjct: 2434 GYLL------EEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRCPPGFTQHH 2480 Score = 105 bits (263), Expect = 1e-22 Identities = 62/182 (34%), Positives = 82/182 (45%), Gaps = 22/182 (12%) Query: 64 DINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN 123 DI+EC + C N GS+ C C G+ N C+DVDEC Sbjct: 1721 DIDECGEIPAICANGI--CINQIGSFRCECPAGFN--------YNSILLACEDVDECGSR 1770 Query: 124 PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGS 183 C+ C+N GSY C+C G+K P C NEC N C S C++ GS Sbjct: 1771 ESPCQQNADCINIPGSYRCKCTRGYKLSPGG--ACVGRNECREIPNVC-SHGDCMDTEGS 1827 Query: 184 YQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP 243 Y C C G+Q + T+C D+DEC + C + T C N +GSY+C C PG+ Sbjct: 1828 YMCLCHRGFQA------SADQTLCMDIDECD--RQPCGNGT-CKNIIGSYNCLCFPGFVV 1878 Query: 244 RH 245 H Sbjct: 1879 TH 1880 Score = 105 bits (263), Expect = 1e-22 Identities = 76/243 (31%), Positives = 105/243 (43%), Gaps = 35/243 (14%) Query: 13 LTLPGAETQDSRGCARWCP-QNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINEC 68 L G D+ C+ P +C N C C GF + TC+DI+EC Sbjct: 2117 LDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMM------TCEDIDEC 2170 Query: 69 ATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCK 128 + + + C NTEGSY C C GY E C+DVDEC + C Sbjct: 2171 SLNPLLCAFR---CHNTEGSYLCTCPAGYT--------LREDGAMCRDVDECADGQQDCH 2219 Query: 129 SYGT-CVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCR 187 + G C N +G++ C C PG + +P + CTD NEC + + C + C+N GS++C Sbjct: 2220 ARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNG-RCVNTAGSFRCD 2278 Query: 188 CRPGWQPIPGSPNGPNNTVCEDVDE--CSSG--QHQCDSSTVCFNTVGSYSCRC--RPGW 241 C G+QP P T C D+ + C + Q C S + V C C GW Sbjct: 2279 CDEGFQP------SPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW 2332 Query: 242 KPR 244 PR Sbjct: 2333 GPR 2335 Score = 105 bits (261), Expect = 2e-22 Identities = 62/160 (38%), Positives = 83/160 (51%), Gaps = 22/160 (13%) Query: 82 CWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT 141 C T SY C C+ GY + C DVDEC +P C +G CVN G+Y Sbjct: 424 CLPTPSSYRCECNVGYT---------QDVRGECIDVDECTSSP--CH-HGDCVNIPGTYH 471 Query: 142 CQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNG 201 C+C PGF+ P + C DV+EC CH C+N GS+QC C G++ SP+G Sbjct: 472 CRCYPGFQATP-TRQACVDVDECIVSGGLCHLG-RCVNTEGSFQCVCNAGFEL---SPDG 526 Query: 202 PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241 N C D +EC++ C + VC N GS+SC C+PG+ Sbjct: 527 KN---CVDHNECATST-MCVNG-VCLNEDGSFSCLCKPGF 561 Score = 101 bits (252), Expect = 3e-21 Identities = 86/293 (29%), Positives = 112/293 (38%), Gaps = 97/293 (33%) Query: 22 DSRGCA--RWCPQNSSCVNAT--------ACRCNPGFSSFSEIITTPTETCDDINECATP 71 D + C C ++ CVN +C C PGF ++ C DI+EC TP Sbjct: 525 DGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGF-----LLAPGGHYCMDIDECQTP 579 Query: 72 SKVSCGKFSDCWNTEGSYDC----------------------VCSPGYEPVSGAKTFKN- 108 G C NTEGS+ C C E S A+ F Sbjct: 580 GICVNGH---CTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGT 636 Query: 109 --ESENTC------------------------------------QDVDECQQNPRLCKSY 130 +SE C +D++EC +P +C + Sbjct: 637 VTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGRDINECALDPEVCAN- 695 Query: 131 GTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 190 G C N GSY C C G++ K CTDV+EC C + C N+ GSY C C P Sbjct: 696 GVCENLRGSYRCVCNLGYE-AGASGKDCTDVDECALNSLLCDNGW-CQNSPGSYSCSCPP 753 Query: 191 G---WQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 240 G WQ + +C+DVDEC S C S VC N GSY+C+C PG Sbjct: 754 GFHFWQ---------DTEICKDVDECLSSP--CVSG-VCRNLAGSYTCKCGPG 794 Score = 97.4 bits (241), Expect = 5e-20 Identities = 60/170 (35%), Positives = 78/170 (45%), Gaps = 23/170 (13%) Query: 26 CARWCPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDC 82 C R N +C N C C PGF + T C D +EC T C +F C Sbjct: 1851 CDRQPCGNGTCKNIIGSYNCLCFPGF------VVTHNGDCVDFDECTTLVGQVC-RFGHC 1903 Query: 83 WNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTC 142 NT GS+ C+C G+E + K C D +EC C GTC N GS+ C Sbjct: 1904 LNTAGSFHCLCQDGFELTADGK--------NCVDTNECLSLAGTCLP-GTCQNLEGSFRC 1954 Query: 143 QCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGW 192 C PGF+ + C D++EC+ N C T C N+ GS+QC C PG+ Sbjct: 1955 ICPPGFQVQSDH---CIDIDECSEEPNLCLFGT-CTNSPGSFQCLCPPGF 2000 Score = 95.5 bits (236), Expect = 2e-19 Identities = 73/240 (30%), Positives = 105/240 (43%), Gaps = 47/240 (19%) Query: 32 QNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGS 88 Q CVN C C PG+ ++ T C+DI+EC+T S + CG C+NT G+ Sbjct: 1575 QGGDCVNTFGSFQCECPPGYH-----LSEHTRICEDIDECSTHSGI-CGP-GTCYNTLGN 1627 Query: 89 YDCVCSPGYEPVSGAK----------------TFKNE-SENTCQDVDECQQN-----PRL 126 Y CVC Y V+G T +NE + N + + C N R Sbjct: 1628 YTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQAWNRP 1687 Query: 127 CKSYGTCVNTLGSYTC-QCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQ 185 C++ T ++ C PGF K D++EC C + C+N +GS++ Sbjct: 1688 CEACPTPISPDYQILCGNQAPGFLTDIHTGKP-LDIDECGEIPAICANGI-CINQIGSFR 1745 Query: 186 CRCRPGWQPIPGSPNGPNNTV---CEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 242 C C G+ N++ CEDVDEC S + C + C N GSY C+C G+K Sbjct: 1746 CECPAGFN---------YNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYK 1796 Score = 89.4 bits (220), Expect = 1e-17 Identities = 68/230 (29%), Positives = 95/230 (41%), Gaps = 43/230 (18%) Query: 36 CVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCV 92 CVN C CN GF ++ + C D NECAT + G C N +GS+ C+ Sbjct: 505 CVNTEGSFQCVCNAGFE-----LSPDGKNCVDHNECATSTMCVNGV---CLNEDGSFSCL 556 Query: 93 CSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIP 152 C PG+ G + C D+DECQ P +C + G C NT GS+ CQCL G + Sbjct: 557 CKPGFLLAPGG--------HYCMDIDECQ-TPGICVN-GHCTNTEGSFRCQCLGGLA-VG 605 Query: 153 EDPKVCTDVN---ECTSGQNPCHSSTHCLNNVGSYQCRCR-------PGWQPIPGSPNGP 202 D +VC D + C + V +C C Q P + Sbjct: 606 TDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAE 665 Query: 203 NNTVCE----------DVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 242 +C D++EC+ C ++ VC N GSY C C G++ Sbjct: 666 FQALCSSGLGITTDGRDINECALDPEVC-ANGVCENLRGSYRCVCNLGYE 714 Score = 87.4 bits (215), Expect = 5e-17 Identities = 74/266 (27%), Positives = 100/266 (37%), Gaps = 73/266 (27%) Query: 33 NSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSY 89 N C+NA C C GF T C D++ECA + + F C N G + Sbjct: 1375 NGQCLNAPGGYRCECEMGFDP-----TEDHRACQDVDECAQGNLCA---FGSCENLPGMF 1426 Query: 90 DCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK 149 C+C+ GYE G C D++EC +P C + G C+NT GSY C C F+ Sbjct: 1427 RCICNGGYELDRGG--------GNCTDINECA-DPVNCIN-GVCINTPGSYLCSCPQDFE 1476 Query: 150 FIPEDPKVCTDVNE-------------------------------CTSGQ---NPCHSST 175 P C D C+ G+ NPC Sbjct: 1477 LNPSGVG-CVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCP 1535 Query: 176 HCLNNVGSYQCRCRPGWQPIPGSPNGPN--NTVCEDVDECSSGQHQCDSSTVCFNTVGSY 233 + N Y+ C PG G PN + ED+DEC C C NT GS+ Sbjct: 1536 --MANTTEYRTLC-PG-----GEGFQPNRITVILEDIDECQELPGLCQGGD-CVNTFGSF 1586 Query: 234 SCRCRPGWKPRHGIPNNQKDTVCEDM 259 C C PG+ ++ +CED+ Sbjct: 1587 QCECPPGYH------LSEHTRICEDI 1606 Score = 84.7 bits (208), Expect = 3e-16 Identities = 50/129 (38%), Positives = 66/129 (51%), Gaps = 15/129 (11%) Query: 115 QDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPK-VCTDVNECTSGQNPCHS 173 Q +D C+ LC + G C+ T SY C+C G+ +D + C DV+ECTS +PCH Sbjct: 407 QTIDICRHFTNLCLN-GRCLPTPSSYRCECNVGYT---QDVRGECIDVDECTS--SPCHH 460 Query: 174 STHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSY 233 C+N G+Y CRC PG+Q P C DVDEC C C NT GS+ Sbjct: 461 GD-CVNIPGTYHCRCYPGFQATP------TRQACVDVDECIVSGGLCHLGR-CVNTEGSF 512 Query: 234 SCRCRPGWK 242 C C G++ Sbjct: 513 QCVCNAGFE 521 Score = 82.8 bits (203), Expect = 1e-15 Identities = 51/166 (30%), Positives = 72/166 (43%), Gaps = 24/166 (14%) Query: 30 CPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTE 86 C + C N C C+ GF+ + + C+D+NEC P + G C N Sbjct: 2496 CGAHGHCHNTPGSFRCECHQGFT-----LVSSGHGCEDVNECDGPHRCQHG----CQNQL 2546 Query: 87 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 146 G Y C C G+ ++ C D +EC +P C S +C NTLG + C C Sbjct: 2547 GGYRCSCPQGFT--------QHSQWAQCVDENECALSPPTCGS-ASCRNTLGGFRCVCPS 2597 Query: 147 GFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGW 192 GF F + C +V+EC + PC S C N G + C C G+ Sbjct: 2598 GFDF-DQALGGCQEVDECAGRRGPC--SYSCANTPGGFLCGCPQGY 2640 Score = 78.6 bits (192), Expect = 2e-14 Identities = 40/121 (33%), Positives = 62/121 (51%), Gaps = 7/121 (5%) Query: 115 QDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSS 174 +D+DECQ+ P LC+ G CVNT GS+ C+C PG+ + E ++C D++EC++ C Sbjct: 1562 EDIDECQELPGLCQG-GDCVNTFGSFQCECPPGY-HLSEHTRICEDIDECSTHSGICGPG 1619 Query: 175 THCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYS 234 T C N +G+Y C C + + NG NN + C + + + FN Sbjct: 1620 T-CYNTLGNYTCVCPAEYLQV----NGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMC 1674 Query: 235 C 235 C Sbjct: 1675 C 1675 Score = 75.1 bits (183), Expect = 3e-13 Identities = 66/234 (28%), Positives = 87/234 (37%), Gaps = 41/234 (17%) Query: 44 CNPGFSSFSEIITTPTETCDDINECAT-PSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSG 102 C GF+ + + TCDD+NEC + P G+ C NT GS+ C C G + Sbjct: 855 CARGFARMTGV------TCDDVNECESFPGVCPNGR---CVNTAGSFRCECPEGLMLDAS 905 Query: 103 AKTFKNESENTC---QDVDECQQNPRLCKSYGTCVNTLGSY---TCQCLP---------- 146 + + C D DEC C ++G+ C+ P Sbjct: 906 GRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASL 965 Query: 147 ---GFKFIPED----PKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSP 199 G F D DVNEC C T C N VGS+ C C G+ Sbjct: 966 CPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT-CRNTVGSFHCACAGGFALDAQER 1024 Query: 200 NGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKD 253 N C D+DEC C T C NT GS+ C C PG++ + N D Sbjct: 1025 N------CTDIDECRISPDLCGQGT-CVNTPGSFECECFPGYESGFMLMKNCMD 1071 Score = 67.0 bits (162), Expect = 7e-11 Identities = 74/291 (25%), Positives = 110/291 (37%), Gaps = 90/291 (30%) Query: 29 WCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVS------------- 75 WC QNS + +C C PGF + + TE C D++EC + VS Sbjct: 739 WC-QNSP--GSYSCSCPPGFHFWQD-----TEICKDVDECLSSPCVSGVCRNLAGSYTCK 790 Query: 76 CGKFS---------------DCW----------NTEGSY---DCVCSPG----------- 96 CG S CW N +G+ +C + G Sbjct: 791 CGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCE 850 Query: 97 YEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPK 156 +P A+ F + TC DV+EC+ P +C + G CVNT GS+ C+C G + + Sbjct: 851 IDPAC-ARGFARMTGVTCDDVNECESFPGVCPN-GRCVNTAGSFRCECPEGL-MLDASGR 907 Query: 157 VCTDV-----------NECTSGQNPCHSSTHCLNNVGS---YQCRCRPGWQPIPGS---P 199 +C DV +EC + C ++G+ +C P + + + P Sbjct: 908 LCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCP 967 Query: 200 NG---------PNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 241 G +DV+EC C T C NTVGS+ C C G+ Sbjct: 968 RGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT-CRNTVGSFHCACAGGF 1017 Score = 53.1 bits (126), Expect = 1e-06 Identities = 39/145 (26%), Positives = 51/145 (35%), Gaps = 16/145 (11%) Query: 26 CARWCPQNSSCVNATACRCNPGFSSFS---EIITTPT------ETCD-DINECATPSKVS 75 C R C C+ C C GF + T P E C + + Sbjct: 151 CDRGCHNGGRCIGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALC 210 Query: 76 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVN 135 C W C P N CQDVDECQ P LC+ G+CVN Sbjct: 211 CATVGRAWGLP----CELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQG-GSCVN 265 Query: 136 TLGSYTCQCLPGFKFIPEDPKVCTD 160 +GS+ C+C G + + + C D Sbjct: 266 MVGSFHCRCPVGHR-LSDSSAACED 289 Score = 45.4 bits (106), Expect = 2e-04 Identities = 72/273 (26%), Positives = 90/273 (32%), Gaps = 61/273 (22%) Query: 3 GRVFLAFCV--WLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE 60 G F A+C W T PG C R C + C C C G T Sbjct: 61 GSRFHAYCCPGWRTFPGRSQCVVPICRRACGEGF-CSQPNLCTCADG---------TLAP 110 Query: 61 TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYE-PVSGAKTFKNESEN--TCQDV 117 +C + VSC C C+C GY V G N C Sbjct: 111 SCGVSR--GSGCSVSCMNGGTCRGAS----CLCQKGYTGTVCGQPICDRGCHNGGRCIGP 164 Query: 118 DECQ-----QNPRLCKSY--GTCVNTLGSYTCQC-LPGFKFIPEDPKVCTDVNEC-TSGQ 168 + C P+ + Y G C +G CQ L G VCT C T G+ Sbjct: 165 NRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGL--------VCTKALCCATVGR 216 Query: 169 N---PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTV 225 PC + CR G+ IP G C+DVDEC + C + Sbjct: 217 AWGLPCELCP-------AQPHPCRRGF--IPNIHTG----ACQDVDECQAVPGLCQGGS- 262 Query: 226 CFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCED 258 C N VGS+ CRC G + + CED Sbjct: 263 CVNMVGSFHCRCPVGHR------LSDSSAACED 289 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.136 0.441 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 35,725,865 Number of Sequences: 37866 Number of extensions: 1767206 Number of successful extensions: 9501 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 189 Number of HSP's successfully gapped in prelim test: 118 Number of HSP's that attempted gapping in prelim test: 4531 Number of HSP's gapped (non-prelim): 1417 length of query: 835 length of database: 18,247,518 effective HSP length: 111 effective length of query: 724 effective length of database: 14,044,392 effective search space: 10168139808 effective search space used: 10168139808 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.