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Search of human proteins with 17864088
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17864088 sorting nexin 13 [Homo sapiens]
(957 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17864088 sorting nexin 13 [Homo sapiens] 1917 0.0
gi|38708169 sorting nexin 25 [Homo sapiens] 203 7e-52
gi|24797145 sorting nexin 14 isoform a [Homo sapiens] 83 1e-15
gi|157502171 sorting nexin 19 [Homo sapiens] 62 2e-09
gi|66472382 nischarin [Homo sapiens] 58 4e-08
gi|24797143 sorting nexin 14 isoform b [Homo sapiens] 56 1e-07
gi|31543452 PX domain containing serine/threonine kinase [Homo s... 54 7e-07
gi|13654235 regulator of G-protein signaling 20 isoform b [Homo ... 51 5e-06
gi|41281805 regulator of G-protein signaling 20 isoform a [Homo ... 51 5e-06
gi|34452688 regulator of G-protein signalling 11 isoform 1 [Homo... 50 8e-06
gi|4506507 regulator of G-protein signalling 11 isoform 2 [Homo ... 50 8e-06
gi|115387108 regulator of G-protein signalling 1 [Homo sapiens] 50 1e-05
gi|23238244 sorting nexin 16 isoform a [Homo sapiens] 49 3e-05
gi|23238246 sorting nexin 16 isoform a [Homo sapiens] 49 3e-05
gi|154091028 sorting nexin 29 [Homo sapiens] 49 3e-05
gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [H... 47 1e-04
gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [H... 47 1e-04
gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [H... 47 1e-04
gi|4506509 regulator of G-protein signalling 12 isoform 2 [Homo ... 46 1e-04
gi|38327601 regulator of G-protein signalling 12 isoform 1 [Homo... 46 1e-04
gi|38327599 regulator of G-protein signalling 12 isoform 3 [Homo... 46 1e-04
gi|21493033 A-kinase anchor protein 10 precursor [Homo sapiens] 46 2e-04
gi|21361405 regulator of G-protein signalling 17 [Homo sapiens] 45 3e-04
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 45 3e-04
gi|23111036 sorting nexin 1 isoform c [Homo sapiens] 43 0.001
gi|23111034 sorting nexin 1 isoform a [Homo sapiens] 43 0.001
gi|164664488 regulator of G-protein signaling 4 isoform 3 [Homo ... 42 0.004
gi|5032039 regulator of G-protein signaling 4 isoform 2 [Homo sa... 42 0.004
gi|156416012 regulator of G-protein signaling 4 isoform 1 [Homo ... 42 0.004
gi|23397574 sorting nexin 33 [Homo sapiens] 42 0.004
>gi|17864088 sorting nexin 13 [Homo sapiens]
Length = 957
Score = 1917 bits (4966), Expect = 0.0
Identities = 957/957 (100%), Positives = 957/957 (100%)
Query: 1 MLTEASLSIWGWGSLGIVLFLITFGPFVIFYLTFYILCFVGGGLVVTLLFGKTNSEKYLE 60
MLTEASLSIWGWGSLGIVLFLITFGPFVIFYLTFYILCFVGGGLVVTLLFGKTNSEKYLE
Sbjct: 1 MLTEASLSIWGWGSLGIVLFLITFGPFVIFYLTFYILCFVGGGLVVTLLFGKTNSEKYLE 60
Query: 61 QCEHSFLPPTSPGVPKCLEEMKREARTIKIDRRLTGANIIDEPLQQVIQFSLRDYVQYWY 120
QCEHSFLPPTSPGVPKCLEEMKREARTIKIDRRLTGANIIDEPLQQVIQFSLRDYVQYWY
Sbjct: 61 QCEHSFLPPTSPGVPKCLEEMKREARTIKIDRRLTGANIIDEPLQQVIQFSLRDYVQYWY 120
Query: 121 YTLSDDESFLLEIRQTLQNALIQFATRSKEIDWQPYFTTRIVDDFGTHLRVFRKAQQKIT 180
YTLSDDESFLLEIRQTLQNALIQFATRSKEIDWQPYFTTRIVDDFGTHLRVFRKAQQKIT
Sbjct: 121 YTLSDDESFLLEIRQTLQNALIQFATRSKEIDWQPYFTTRIVDDFGTHLRVFRKAQQKIT 180
Query: 181 EKDDQVKGTAEDLVDTFFEVEVEMEKEVCRDLVCTSPKDEEGFLRDLCEVLLYLLLPPGD 240
EKDDQVKGTAEDLVDTFFEVEVEMEKEVCRDLVCTSPKDEEGFLRDLCEVLLYLLLPPGD
Sbjct: 181 EKDDQVKGTAEDLVDTFFEVEVEMEKEVCRDLVCTSPKDEEGFLRDLCEVLLYLLLPPGD 240
Query: 241 FQNKIMRYFVREILARGILLPLINQLSDPDYINQYVIWMIRDSNCNYEAFMNIIKLSDNI 300
FQNKIMRYFVREILARGILLPLINQLSDPDYINQYVIWMIRDSNCNYEAFMNIIKLSDNI
Sbjct: 241 FQNKIMRYFVREILARGILLPLINQLSDPDYINQYVIWMIRDSNCNYEAFMNIIKLSDNI 300
Query: 301 GELEAVRDKAAEELQYLRSLDTAGDDINTIKNQINSLLFVKKVCDSRIQRLQSGKEINTV 360
GELEAVRDKAAEELQYLRSLDTAGDDINTIKNQINSLLFVKKVCDSRIQRLQSGKEINTV
Sbjct: 301 GELEAVRDKAAEELQYLRSLDTAGDDINTIKNQINSLLFVKKVCDSRIQRLQSGKEINTV 360
Query: 361 KLAANFGKLCTVPLDSILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYRVTAQQQLEVL 420
KLAANFGKLCTVPLDSILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYRVTAQQQLEVL
Sbjct: 361 KLAANFGKLCTVPLDSILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYRVTAQQQLEVL 420
Query: 421 LSRQRDGKHQTNQTKGLLRAAAVGIYEQYLSEKASPRVTVDDYLVAKLADTLNHEDPTPE 480
LSRQRDGKHQTNQTKGLLRAAAVGIYEQYLSEKASPRVTVDDYLVAKLADTLNHEDPTPE
Sbjct: 421 LSRQRDGKHQTNQTKGLLRAAAVGIYEQYLSEKASPRVTVDDYLVAKLADTLNHEDPTPE 480
Query: 481 IFDDIQRKVYELMLRDERFYPSFRQNALYVRMLAELDMLKDPSFRGSDDGDGESFNGSPT 540
IFDDIQRKVYELMLRDERFYPSFRQNALYVRMLAELDMLKDPSFRGSDDGDGESFNGSPT
Sbjct: 481 IFDDIQRKVYELMLRDERFYPSFRQNALYVRMLAELDMLKDPSFRGSDDGDGESFNGSPT 540
Query: 541 GSINLSLDDLSNVSSDDSVQLHAYISDTGVCNDHGKTYALYAITVHRRNLNSEEMWKTYR 600
GSINLSLDDLSNVSSDDSVQLHAYISDTGVCNDHGKTYALYAITVHRRNLNSEEMWKTYR
Sbjct: 541 GSINLSLDDLSNVSSDDSVQLHAYISDTGVCNDHGKTYALYAITVHRRNLNSEEMWKTYR 600
Query: 601 RYSDFHDFHMRITEQFESLSSILKLPGKKTFNNMDRDFLEKRKKDLNAYLQLLLAPEMMK 660
RYSDFHDFHMRITEQFESLSSILKLPGKKTFNNMDRDFLEKRKKDLNAYLQLLLAPEMMK
Sbjct: 601 RYSDFHDFHMRITEQFESLSSILKLPGKKTFNNMDRDFLEKRKKDLNAYLQLLLAPEMMK 660
Query: 661 ASPALAHYVYDFLENKAYSKGKGDFARKMDTFVNPLRNSMRNVSNAVKSLPDSLAEGMTK 720
ASPALAHYVYDFLENKAYSKGKGDFARKMDTFVNPLRNSMRNVSNAVKSLPDSLAEGMTK
Sbjct: 661 ASPALAHYVYDFLENKAYSKGKGDFARKMDTFVNPLRNSMRNVSNAVKSLPDSLAEGMTK 720
Query: 721 MSDNMGKMSERLGQDIKQSFFKVPPLIPKTDSDPEHRRVSAQLDDNVDDNIPLRVMLLLM 780
MSDNMGKMSERLGQDIKQSFFKVPPLIPKTDSDPEHRRVSAQLDDNVDDNIPLRVMLLLM
Sbjct: 721 MSDNMGKMSERLGQDIKQSFFKVPPLIPKTDSDPEHRRVSAQLDDNVDDNIPLRVMLLLM 780
Query: 781 DEVFDLKERNQWLRRNIKNLLQQLIRATYGDTINRKIVDHVDWMTSPEQVADSVKRFRDA 840
DEVFDLKERNQWLRRNIKNLLQQLIRATYGDTINRKIVDHVDWMTSPEQVADSVKRFRDA
Sbjct: 781 DEVFDLKERNQWLRRNIKNLLQQLIRATYGDTINRKIVDHVDWMTSPEQVADSVKRFRDA 840
Query: 841 FWPNGILAEAVPCRDKSIRMRTRVAGKTKLLAIMPDELKHIIGAETTRKGILRVFEMFQH 900
FWPNGILAEAVPCRDKSIRMRTRVAGKTKLLAIMPDELKHIIGAETTRKGILRVFEMFQH
Sbjct: 841 FWPNGILAEAVPCRDKSIRMRTRVAGKTKLLAIMPDELKHIIGAETTRKGILRVFEMFQH 900
Query: 901 NQLNRRMVYVFLEGFLETLFPQYKFRELFNKLHSRSKQMQKYKQKLQTTQAPSLQKR 957
NQLNRRMVYVFLEGFLETLFPQYKFRELFNKLHSRSKQMQKYKQKLQTTQAPSLQKR
Sbjct: 901 NQLNRRMVYVFLEGFLETLFPQYKFRELFNKLHSRSKQMQKYKQKLQTTQAPSLQKR 957
>gi|38708169 sorting nexin 25 [Homo sapiens]
Length = 840
Score = 203 bits (516), Expect = 7e-52
Identities = 229/936 (24%), Positives = 378/936 (40%), Gaps = 218/936 (23%)
Query: 100 IDEPLQQVIQFSLRDYVQYWYYTLSDDESFLLEIRQTLQNALIQFATRSKEIDWQPYFTT 159
+D+ L++V +S RDY+ WY LS DE L +
Sbjct: 1 MDKALKEVFDYSYRDYILSWYGNLSRDEGQLYHL-------------------------- 34
Query: 160 RIVDDFGTHLRVFRKAQQKITEKDDQVKGTAEDLVDTFFEVEVEME------KEVCRDLV 213
+++DF + R+ +++ D VK D+V T +++ +E R V
Sbjct: 35 -LLEDFW---EIARQLHHRLSHVD-VVKVVCNDVVRTLLTHFCDLKAANARHEEQPRPFV 89
Query: 214 ---CTSPKDEE-GFLRDLCEVLLYLLLPPGDFQNKIMRYFVREILARGILLPLINQLSDP 269
C D+E FL+ VL++ LLP D Q+ +R + EIL +L P++ LS+P
Sbjct: 90 LHACLRNSDDEVRFLQTCSRVLVFCLLPSKDVQSLSLRIMLAEILTTKVLKPVVELLSNP 149
Query: 270 DYINQYVIWMIRDSNC-------------NYEAFMNIIKLSDNIGELEAVRDKAAEE--- 313
DYINQ ++ + +YE F+ +I + ++ L+ +R + E
Sbjct: 150 DYINQMLLAQLAYREQMNEHHKRAYTYAPSYEDFIKLINSNSDVEFLKQLRYQIVVEIIQ 209
Query: 314 ---------LQYLRSLDTAGDDINTI-----KNQINSLLFVKKVCDSRIQRLQSGKEINT 359
L+ + +TA + + K IN L KK C+ RI+ L
Sbjct: 210 ATTISSFPQLKRHKGKETAAMKADLLRARNMKRYINQLTVAKKQCEKRIRILGGPAYDQQ 269
Query: 360 VKLAANFGK----LCTVPLDSILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYRVTAQQ 415
A + G+ + + IL + + F YM++ +A + FW +VE
Sbjct: 270 EDGALDEGEGPQSQKILQFEDILANTFYREHFGMYMERMDKRALISFWESVE-------- 321
Query: 416 QLEVLLSRQRDGKHQTNQTKGLLRAAAVGIYEQYLSEKASPRVTVDDYLVAKLADTLNHE 475
H N K + IY+ + E S ++V+ L ++ L
Sbjct: 322 -------------HLKNANKNEIPQLVGEIYQNFFVE--SKEISVEKSLYKEIQQCLVGN 366
Query: 476 DPTPEIFDDIQRKVYELMLRDERFYPSFRQNALYVRMLAELD------MLKDPSFRGSDD 529
E+F IQ VYE + +R+YPSF + LY ++L + + M+ + G D
Sbjct: 367 KGI-EVFYKIQEDVYETL--KDRYYPSFIVSDLYEKLLIKEEEKHASQMISNKDEMGPRD 423
Query: 530 GDGESFNGSPTGSIN---------------------LSLDDLSNVSSDDS---------- 558
GE T IN +L+ + N D
Sbjct: 424 EAGEEAVDDGTNQINEQASFAVNKLRELNEKLEYKRQALNSIQNAPKPDKKIVSKLKDEI 483
Query: 559 ---------VQLH---------------AYISDTGVCNDHGKTYALYAITVHRRNLNSEE 594
+QLH A I+ V ++G+ Y + V + + E
Sbjct: 484 ILIEKERTDLQLHMARTDWWCENLGMWKASITSGEVTEENGEQLPCYFVMVSLQEVGGVE 543
Query: 595 M--WKTYRRYSDFHDFHMRITEQFESLSSILKLPG--KKTFNNMDRDFLEKRKKDLNAYL 650
W RR S+F + H +++E SL + +LP K F ++D+ F+EK K LN +L
Sbjct: 544 TKNWTVPRRLSEFQNLHRKLSECVPSLKKV-QLPSLSKLPFKSIDQKFMEKSKNQLNKFL 602
Query: 651 QLLLAPEMMKASPALAHYVYDFLENKAYSKGKGDFARKMDTFVNPLRNSMRNVSNAVKSL 710
Q LL+ E + S AL Y FL D+ + +D V +NS
Sbjct: 603 QNLLSDERLCQSEAL----YAFLSPSP------DYLKVID--VQGKKNSF---------- 640
Query: 711 PDSLAEGMTKMSDNMGKMSERLGQDIKQSFFKVPPLIPKTDSDPEHRRVSAQLDDNVDD- 769
++ ERL +D FF + DSD + D+VD
Sbjct: 641 -------------SLSSFLERLPRD----FFSHQEEETEEDSD------LSDYGDDVDGR 677
Query: 770 -NIPLRVMLLLMDEVFDLKERNQWLRRNIKNLLQQLIRATYGDTINRKIVDHVDWMTSPE 828
+ +L+ E+F+L+ +W+RR L L++ T+G TIN++I D V W+ S +
Sbjct: 678 KDALAEPCFMLIGEIFELRGMFKWVRRT----LIALVQVTFGRTINKQIRDTVSWIFSEQ 733
Query: 829 QVADSVKRFRDAFWPNGILAEAVPCRDKSIRMRTRVAGKTKLLAIMPDELKHIIGAETTR 888
+ + FRDAFWPNG LA R K T+ + KLL +PD L+ ++G + R
Sbjct: 734 MLVYYINIFRDAFWPNGKLAPPTTIRSKEQSQETKQRAQQKLLENIPDMLQSLVGQQNAR 793
Query: 889 KGILRVFEMFQHNQLNRRMVYVFLEGFLETLFPQYK 924
GI+++F Q + N+ ++Y +E L L P+ +
Sbjct: 794 HGIIKIFNALQETRANKHLLYALMELLLIELCPELR 829
>gi|24797145 sorting nexin 14 isoform a [Homo sapiens]
Length = 946
Score = 82.8 bits (203), Expect = 1e-15
Identities = 54/184 (29%), Positives = 92/184 (50%), Gaps = 13/184 (7%)
Query: 100 IDEPLQQVIQFSLRDYVQYWYYTLSDDESFLLEIRQTLQNALIQFATRSKEIDWQPYFTT 159
+D L +V++ L ++V WY ++DDESF+ E+R TL+ R ++D T
Sbjct: 133 VDASLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLIRRIHKVDIPSIITK 192
Query: 160 RIVDDFGTHLRVFRKAQQKITEKDDQVKGTAEDLVDTFFEVEVEMEKEVCRDLVCTSPKD 219
+++ H+ V KA+QK+ + + E+ E+ V + S +D
Sbjct: 193 KLLKAAMKHIEVIVKARQKVKNTEFLQQAALEEYGP---ELHVALR----------SRRD 239
Query: 220 EEGFLRDLCEVLLYLLLPPGDFQNKIMRYFVREILARGILLPLINQLSDPDYINQYVIWM 279
E +LR L E+L +LPP + + +REIL+ + LP ++ L+DPD +N +I
Sbjct: 240 ELHYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIF 299
Query: 280 IRDS 283
I DS
Sbjct: 300 IDDS 303
Score = 56.2 bits (134), Expect = 1e-07
Identities = 81/371 (21%), Positives = 151/371 (40%), Gaps = 75/371 (20%)
Query: 587 RRNLNSE-EMWKTYRRYSDFHDFHMRITEQFESLSSILKLPGKKTFNNMDRDFLEKRKKD 645
RR + E E W YRRY +F+ ++TE F +LP K+ + +FL+ ++++
Sbjct: 601 RRAVGHEPEHWSVYRRYLEFYVLESKLTE-FHGAFPDAQLPSKRIIGPKNYEFLKSKREE 659
Query: 646 LNAYLQLLLAPEMMKASPALAHYVYDFLENKAYSKGKGDFARKMDTFVNPLRNSMRNVSN 705
YLQ LL + S LA DFL G+ F K+ V N+
Sbjct: 660 FQEYLQKLLQHPELSNSQLLA----DFLSPNG---GETQFLDKILPDV--------NLGK 704
Query: 706 AVKSLPDSLAEGMTKMSDNMGKMSERLGQDIK---QSFFKVPPLIPKTDSDPEHRRVSAQ 762
+KS+P GK+ + GQ ++ +F S PE +S
Sbjct: 705 IIKSVP--------------GKLMKEKGQHLEPFIMNFINSCESPKPKPSRPELTILSPT 750
Query: 763 LDDNVDDNIPLRVMLLLMDEVF--DLKERNQWLRRNIKNLLQQLIRA----TYGDTINRK 816
++N L +++F + R+ +N +++ Y + R
Sbjct: 751 SENNKK----------LFNDLFKNNANRAENTERKQNQNYFMEVMTVEGVYDYLMYVGRV 800
Query: 817 IVDHVDW-----MTSPEQVADSVKRFRDAFWPNGI---------------LAEAVPCRD- 855
+ DW M + ++++ + D + + L +A+ C +
Sbjct: 801 VFQVPDWLHHLLMGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENT 860
Query: 856 --KSIRMRTRVAGKT--KLLAIMPDELKHIIGAETTRKGILRVFEMFQHNQLNRRMVYVF 911
+S++ + + A +T +++ +PD L IG ET + I +F+ Q LN+++ YV
Sbjct: 861 EPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGEETKYESIRLLFDGLQQPVLNKQLTYVL 920
Query: 912 LEGFLETLFPQ 922
L+ ++ LFP+
Sbjct: 921 LDIVIQELFPE 931
>gi|157502171 sorting nexin 19 [Homo sapiens]
Length = 992
Score = 62.4 bits (150), Expect = 2e-09
Identities = 56/246 (22%), Positives = 110/246 (44%), Gaps = 42/246 (17%)
Query: 37 LCFVGGGLVVTLLFGKTNSEKYLEQCEHSFLP-PTSPGVPKCLEEMKREARTIKIDRRLT 95
L V GG + + L G + +LE+ F+P T P P+ +++RE
Sbjct: 57 LLVVLGGWLGSSLAGVASGRLHLER----FIPLATCPPCPEAERQLERE----------- 101
Query: 96 GANIIDEPLQQVIQFSLRDYVQYWYYTLSDDESFLLEIRQTLQNALIQFATRSKEIDWQP 155
+ + IQ +RD+V WY ++S + +F E+ ++ + + R +D
Sbjct: 102 --------INRTIQMIIRDFVLSWYRSVSQEPAFEEEMEAAMKGLVQELRRRMSVMDSHA 153
Query: 156 YFTTRIVDDFGTHLRVFRKAQQKITEKDDQVKGTAEDLVDTFFEVEVEMEKEVCRDLV-- 213
+ ++ G HL+ + +A++ K+ V+ + + + CR
Sbjct: 154 VAQS-VLTLCGCHLQSYIQAKEATAGKNGPVEPS-------------HLWEAYCRATAPH 199
Query: 214 --CTSPKDEEGFLRDLCEVLLYLLLPPGDFQNKIMRYFVREILARGILLPLINQLSDPDY 271
SP E + R + +LL L+P + + R+ V E++ ++LPLI++LSDPD+
Sbjct: 200 PAVHSPSAEVTYTRGVVNLLLQGLVPKPHLETRTGRHVVVELITCNVILPLISRLSDPDW 259
Query: 272 INQYVI 277
I+ ++
Sbjct: 260 IHLVLV 265
Score = 58.5 bits (140), Expect = 3e-08
Identities = 96/464 (20%), Positives = 165/464 (35%), Gaps = 93/464 (20%)
Query: 539 PTGSINLSLDDLSNVSSDDSVQLHAYISDTGVCNDHGKT----YALYAITV-------HR 587
P S S + LS+ +Q + I+ T +H T Y LY + +
Sbjct: 510 PLSSATFSFEPLSSPDGPVIIQ-NLRITGTITAREHSGTGFHPYTLYTVKYETALDGENS 568
Query: 588 RNLNSEEMWKTYRRYSDFHDFHMRITEQFESLSSILKLPGKKT------FNNMDRDFLEK 641
L RRY +F + R+ E+ + I + G K F NMD D +E
Sbjct: 569 SGLQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNVKGPKKLFPDLPFGNMDSDRVEA 628
Query: 642 RKKDLNAYL-QLLLAPEM-----------MKASPALAHYVYDFL---------------- 673
RK L ++L QL PE+ + +A F+
Sbjct: 629 RKSLLESFLKQLCAIPEIANSEEVQEFLALNTDARIAFVKKPFMVSRIDKMVVSAIVDTL 688
Query: 674 ---------------------ENKAYSKGKGDFARKM---DTFVNPLRNSMRNVSNAVKS 709
E+K ++GK ++ + ++P + +
Sbjct: 689 KTAFPRSEPQSPTEELSEAETESKPQTEGKKASKSRLRFSSSKISPALSVTEAQDKILYC 748
Query: 710 LPDSLAEGMTKMSDNMGKMSERLGQDIKQSFFKVPPLIP------KTDSDPEHRRVSAQL 763
L + E T M E+ + ++ K P P + DS V AQ
Sbjct: 749 LQEGNVESETLSMSAMESFIEKQTKLLEMQPTKAPEKDPEQPPKGRVDSCVSDAAVPAQD 808
Query: 764 DDNVDD-------NIPLRVMLLLMDEVFDLKERNQWLRRNIKNLLQQLIRATYGDTINRK 816
N D + L ++LLL+ E QW +N +Q+ +R +G + R
Sbjct: 809 PSNSDPGTETELADTALDLLLLLLTE--------QWKWLCTEN-MQKFLRLIFGTLVQRW 859
Query: 817 IVDHVDWMTSPEQVADSVKRFRDAFWPNGILAE-AVPCRDKSIRMRTRVAGKTKLLAIMP 875
+ V +TSP++ + +++ WP G+L + P R + ++ L+ ++P
Sbjct: 860 LEVQVANLTSPQRWVQYLLLLQESIWPGGVLPKFPRPVRTQEQKLAAEKQALQSLMGVLP 919
Query: 876 DELKHIIGAETTRKGILRVFEMFQHNQLNRRMVYVFLEGFLETL 919
D + I+G R V E Q +NR ++Y + LE L
Sbjct: 920 DLVVEILGVNKCRLSWGLVLESLQQPLINRHLIYCLGDIILEFL 963
>gi|66472382 nischarin [Homo sapiens]
Length = 1504
Score = 58.2 bits (139), Expect = 4e-08
Identities = 34/94 (36%), Positives = 47/94 (50%), Gaps = 6/94 (6%)
Query: 577 TYALYAITVHRRNLNSEEMWKTYRRYSDFHDFHMRITEQFESLSSILKLPGKKTFNNMDR 636
TY +Y I V + W RYSDFHD H ++ + + ++L P KK R
Sbjct: 29 TYTVYIIQV----TDGSHEWTVKHRYSDFHDLHEKLVAERKIDKNLL--PPKKIIGKNSR 82
Query: 637 DFLEKRKKDLNAYLQLLLAPEMMKASPALAHYVY 670
+EKR+KDL YLQ LLA LAH+++
Sbjct: 83 SLVEKREKDLEVYLQKLLAAFPGVTPRVLAHFLH 116
>gi|24797143 sorting nexin 14 isoform b [Homo sapiens]
Length = 893
Score = 56.2 bits (134), Expect = 1e-07
Identities = 81/371 (21%), Positives = 151/371 (40%), Gaps = 75/371 (20%)
Query: 587 RRNLNSE-EMWKTYRRYSDFHDFHMRITEQFESLSSILKLPGKKTFNNMDRDFLEKRKKD 645
RR + E E W YRRY +F+ ++TE F +LP K+ + +FL+ ++++
Sbjct: 548 RRAVGHEPEHWSVYRRYLEFYVLESKLTE-FHGAFPDAQLPSKRIIGPKNYEFLKSKREE 606
Query: 646 LNAYLQLLLAPEMMKASPALAHYVYDFLENKAYSKGKGDFARKMDTFVNPLRNSMRNVSN 705
YLQ LL + S LA DFL G+ F K+ V N+
Sbjct: 607 FQEYLQKLLQHPELSNSQLLA----DFLSPNG---GETQFLDKILPDV--------NLGK 651
Query: 706 AVKSLPDSLAEGMTKMSDNMGKMSERLGQDIK---QSFFKVPPLIPKTDSDPEHRRVSAQ 762
+KS+P GK+ + GQ ++ +F S PE +S
Sbjct: 652 IIKSVP--------------GKLMKEKGQHLEPFIMNFINSCESPKPKPSRPELTILSPT 697
Query: 763 LDDNVDDNIPLRVMLLLMDEVF--DLKERNQWLRRNIKNLLQQLIRA----TYGDTINRK 816
++N L +++F + R+ +N +++ Y + R
Sbjct: 698 SENNKK----------LFNDLFKNNANRAENTERKQNQNYFMEVMTVEGVYDYLMYVGRV 747
Query: 817 IVDHVDW-----MTSPEQVADSVKRFRDAFWPNGI---------------LAEAVPCRD- 855
+ DW M + ++++ + D + + L +A+ C +
Sbjct: 748 VFQVPDWLHHLLMGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENT 807
Query: 856 --KSIRMRTRVAGKT--KLLAIMPDELKHIIGAETTRKGILRVFEMFQHNQLNRRMVYVF 911
+S++ + + A +T +++ +PD L IG ET + I +F+ Q LN+++ YV
Sbjct: 808 EPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGEETKYESIRLLFDGLQQPVLNKQLTYVL 867
Query: 912 LEGFLETLFPQ 922
L+ ++ LFP+
Sbjct: 868 LDIVIQELFPE 878
Score = 54.7 bits (130), Expect = 4e-07
Identities = 38/134 (28%), Positives = 64/134 (47%), Gaps = 13/134 (9%)
Query: 150 EIDWQPYFTTRIVDDFGTHLRVFRKAQQKITEKDDQVKGTAEDLVDTFFEVEVEMEKEVC 209
E+D T +++ H+ V KA+QK+ + + E+ E+ V +
Sbjct: 139 EVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEFLQQAALEEYGP---ELHVALR---- 191
Query: 210 RDLVCTSPKDEEGFLRDLCEVLLYLLLPPGDFQNKIMRYFVREILARGILLPLINQLSDP 269
S +DE +LR L E+L +LPP + + +REIL+ + LP ++ L+DP
Sbjct: 192 ------SRRDELHYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVFLPSLDFLADP 245
Query: 270 DYINQYVIWMIRDS 283
D +N +I I DS
Sbjct: 246 DTVNHLLIIFIDDS 259
>gi|31543452 PX domain containing serine/threonine kinase [Homo
sapiens]
Length = 578
Score = 53.9 bits (128), Expect = 7e-07
Identities = 43/131 (32%), Positives = 63/131 (48%), Gaps = 13/131 (9%)
Query: 556 DDSVQLHAYISDTGVCNDHGKTYALYAITVHRRNLNSEEMWKTYRRYSDFHDFHMRITEQ 615
DD+V L A I + H + Y I V +R ++ E W+ RRYSDF + + Q
Sbjct: 15 DDTVPLTAAIEASQSLQSHTE----YIIRV-QRGISVENSWQIVRRYSDFDLLNNSL--Q 67
Query: 616 FESLSSILKLPGKKTFNNMDRDFLEKRKKDLNAYLQLLLAPEMMKASPALAHYVYDFLEN 675
LS L LP KK NMDR+F+ +R+K L YL ++ ++ + V FL+
Sbjct: 68 IAGLS--LPLPPKKLIGNMDREFIAERQKGLQNYLNVITTNHIL----SNCELVKKFLDP 121
Query: 676 KAYSKGKGDFA 686
YS + A
Sbjct: 122 NNYSANYTEIA 132
>gi|13654235 regulator of G-protein signaling 20 isoform b [Homo
sapiens]
Length = 241
Score = 51.2 bits (121), Expect = 5e-06
Identities = 36/144 (25%), Positives = 64/144 (44%), Gaps = 28/144 (19%)
Query: 375 DSILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYRVTAQQQLEVLLSRQRDGKHQTNQT 434
D ++V F ++++ + ++ FWM E + A
Sbjct: 117 DKLMVTPAGRNAFREFLRTEFSEENMLFWMACEELKKEAN-------------------- 156
Query: 435 KGLLRAAAVGIYEQYLSEKASPRVTVDDYLVAKLADTLNHE--DPTPEIFDDIQRKVYEL 492
K ++ A IYE Y+S + V++D +++ + +N +P+ IFDD Q ++Y L
Sbjct: 157 KNIIEEKARIIYEDYISILSPKEVSLD----SRVREVINRNMVEPSQHIFDDAQLQIYTL 212
Query: 493 MLRDERFYPSFRQNALYVRMLAEL 516
M RD YP F +A+Y +L L
Sbjct: 213 MHRDS--YPRFMNSAVYKDLLQSL 234
>gi|41281805 regulator of G-protein signaling 20 isoform a [Homo
sapiens]
Length = 388
Score = 51.2 bits (121), Expect = 5e-06
Identities = 36/144 (25%), Positives = 64/144 (44%), Gaps = 28/144 (19%)
Query: 375 DSILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYRVTAQQQLEVLLSRQRDGKHQTNQT 434
D ++V F ++++ + ++ FWM E + A
Sbjct: 264 DKLMVTPAGRNAFREFLRTEFSEENMLFWMACEELKKEAN-------------------- 303
Query: 435 KGLLRAAAVGIYEQYLSEKASPRVTVDDYLVAKLADTLNHE--DPTPEIFDDIQRKVYEL 492
K ++ A IYE Y+S + V++D +++ + +N +P+ IFDD Q ++Y L
Sbjct: 304 KNIIEEKARIIYEDYISILSPKEVSLD----SRVREVINRNMVEPSQHIFDDAQLQIYTL 359
Query: 493 MLRDERFYPSFRQNALYVRMLAEL 516
M RD YP F +A+Y +L L
Sbjct: 360 MHRDS--YPRFMNSAVYKDLLQSL 381
>gi|34452688 regulator of G-protein signalling 11 isoform 1 [Homo
sapiens]
Length = 467
Score = 50.4 bits (119), Expect = 8e-06
Identities = 38/139 (27%), Positives = 60/139 (43%), Gaps = 25/139 (17%)
Query: 377 ILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYRVTAQQQLEVLLSRQRDGKHQTNQTKG 436
+L D V FMD++ + +L FW E R AQ Q+ L+
Sbjct: 307 LLEDPVGRAHFMDFLGKEFSGENLSFWEACEELRYGAQAQVPTLVD-------------- 352
Query: 437 LLRAAAVGIYEQYLSEKASPRVTVDDYLVAKLADTLNHEDPTPEIFDDIQRKVYELMLRD 496
+YEQ+L+ A+ V +D + + + L P + DD Q +Y LM +D
Sbjct: 353 -------AVYEQFLAPGAAHWVNIDSRTMEQTLEGL--RQPHRYVLDDAQLHIYMLMKKD 403
Query: 497 ERFYPSFRQNALYVRMLAE 515
YP F ++ +Y +LAE
Sbjct: 404 S--YPRFLKSDMYKALLAE 420
>gi|4506507 regulator of G-protein signalling 11 isoform 2 [Homo
sapiens]
Length = 446
Score = 50.4 bits (119), Expect = 8e-06
Identities = 38/139 (27%), Positives = 60/139 (43%), Gaps = 25/139 (17%)
Query: 377 ILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYRVTAQQQLEVLLSRQRDGKHQTNQTKG 436
+L D V FMD++ + +L FW E R AQ Q+ L+
Sbjct: 286 LLEDPVGRAHFMDFLGKEFSGENLSFWEACEELRYGAQAQVPTLVD-------------- 331
Query: 437 LLRAAAVGIYEQYLSEKASPRVTVDDYLVAKLADTLNHEDPTPEIFDDIQRKVYELMLRD 496
+YEQ+L+ A+ V +D + + + L P + DD Q +Y LM +D
Sbjct: 332 -------AVYEQFLAPGAAHWVNIDSRTMEQTLEGL--RQPHRYVLDDAQLHIYMLMKKD 382
Query: 497 ERFYPSFRQNALYVRMLAE 515
YP F ++ +Y +LAE
Sbjct: 383 S--YPRFLKSDMYKALLAE 399
>gi|115387108 regulator of G-protein signalling 1 [Homo sapiens]
Length = 209
Score = 50.1 bits (118), Expect = 1e-05
Identities = 41/179 (22%), Positives = 77/179 (43%), Gaps = 27/179 (15%)
Query: 340 VKKVCDSRIQRLQSGKEINTVK--LAANFGKLCTVPLDSILVDNVALQFFMDYMQQTGGQ 397
+K S I L+SG + + K L+A + L+ +L + F +++ +
Sbjct: 50 MKAYLRSMIPHLESGMKSSKSKDVLSAAEVMQWSQSLEKLLANQTGQNVFGSFLKSEFSE 109
Query: 398 AHLFFWMTVEGYRVTAQQQLEVLLSRQRDGKHQTNQTKGLLRAAAVGIYEQYLSEKASPR 457
++ FW+ E Y+ T LL A IY+ ++ A+ +
Sbjct: 110 ENIEFWLACEDYKKTESD---------------------LLPCKAEEIYKAFVHSDAAKQ 148
Query: 458 VTVDDYLVAKLADTLNHEDPTPEIFDDIQRKVYELMLRDERFYPSFRQNALYVRMLAEL 516
+ +D A + + PTP FD+ Q+ +Y LM +D YP F ++ +Y+ +L +L
Sbjct: 149 INIDFRTRESTAKKI--KAPTPTCFDEAQKVIYTLMEKDS--YPRFLKSDIYLNLLNDL 203
>gi|23238244 sorting nexin 16 isoform a [Homo sapiens]
Length = 344
Score = 48.5 bits (114), Expect = 3e-05
Identities = 30/79 (37%), Positives = 44/79 (55%), Gaps = 6/79 (7%)
Query: 578 YALYAITVHRRNLNSEEMWKTYRRYSDFHDFHMRITEQFESLSSILKLPGKKTF-NNMDR 636
+ +Y I V + EE W +RRY+DF + ++ E F L LP K+ F +N +
Sbjct: 124 FTVYKILVKK---TPEESWVVFRRYTDFSRLNDKLKEMFPGFR--LALPPKRWFKDNYNA 178
Query: 637 DFLEKRKKDLNAYLQLLLA 655
DFLE R+ L A+LQ L+A
Sbjct: 179 DFLEDRQLGLQAFLQNLVA 197
>gi|23238246 sorting nexin 16 isoform a [Homo sapiens]
Length = 344
Score = 48.5 bits (114), Expect = 3e-05
Identities = 30/79 (37%), Positives = 44/79 (55%), Gaps = 6/79 (7%)
Query: 578 YALYAITVHRRNLNSEEMWKTYRRYSDFHDFHMRITEQFESLSSILKLPGKKTF-NNMDR 636
+ +Y I V + EE W +RRY+DF + ++ E F L LP K+ F +N +
Sbjct: 124 FTVYKILVKK---TPEESWVVFRRYTDFSRLNDKLKEMFPGFR--LALPPKRWFKDNYNA 178
Query: 637 DFLEKRKKDLNAYLQLLLA 655
DFLE R+ L A+LQ L+A
Sbjct: 179 DFLEDRQLGLQAFLQNLVA 197
>gi|154091028 sorting nexin 29 [Homo sapiens]
Length = 428
Score = 48.5 bits (114), Expect = 3e-05
Identities = 27/115 (23%), Positives = 53/115 (46%), Gaps = 14/115 (12%)
Query: 549 DLSNVSSDDSVQ---------LHAYISDTGVCNDHGKTYALYAITVHRRNLNSEEMWKTY 599
DLS S D S+ ++ +I + + +Y + + + ++ W Y
Sbjct: 252 DLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIK----DDEWNIY 307
Query: 600 RRYSDFHDFHMRITEQFESLSSILKLPGKKTFNNMDRDFLEKRKKDLNAYLQLLL 654
RRY++F H ++ ++ + + P KK N D F+E+R+K L YL+ ++
Sbjct: 308 RRYTEFRSLHHKLQNKYPQVRA-YNFPPKKAIGNKDAKFVEERRKQLQNYLRSVM 361
>gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [Homo
sapiens]
Length = 464
Score = 46.6 bits (109), Expect = 1e-04
Identities = 23/65 (35%), Positives = 43/65 (66%), Gaps = 4/65 (6%)
Query: 596 WKTYRRYSDFHDFHMRITEQFESLSSILKLPGKKTF-NNMDRDFLEKRKKDLNAYLQ-LL 653
W +RRY++F + + +QF +++ LK+P K+ F +N D DF+++R+ LN ++Q L+
Sbjct: 45 WFVFRRYAEFDKLYNTLKKQFPAMA--LKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLV 102
Query: 654 LAPEM 658
PE+
Sbjct: 103 RYPEL 107
>gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
sapiens]
Length = 496
Score = 46.6 bits (109), Expect = 1e-04
Identities = 23/65 (35%), Positives = 43/65 (66%), Gaps = 4/65 (6%)
Query: 596 WKTYRRYSDFHDFHMRITEQFESLSSILKLPGKKTF-NNMDRDFLEKRKKDLNAYLQ-LL 653
W +RRY++F + + +QF +++ LK+P K+ F +N D DF+++R+ LN ++Q L+
Sbjct: 45 WFVFRRYAEFDKLYNTLKKQFPAMA--LKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLV 102
Query: 654 LAPEM 658
PE+
Sbjct: 103 RYPEL 107
>gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
sapiens]
Length = 496
Score = 46.6 bits (109), Expect = 1e-04
Identities = 23/65 (35%), Positives = 43/65 (66%), Gaps = 4/65 (6%)
Query: 596 WKTYRRYSDFHDFHMRITEQFESLSSILKLPGKKTF-NNMDRDFLEKRKKDLNAYLQ-LL 653
W +RRY++F + + +QF +++ LK+P K+ F +N D DF+++R+ LN ++Q L+
Sbjct: 45 WFVFRRYAEFDKLYNTLKKQFPAMA--LKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLV 102
Query: 654 LAPEM 658
PE+
Sbjct: 103 RYPEL 107
>gi|4506509 regulator of G-protein signalling 12 isoform 2 [Homo
sapiens]
Length = 1376
Score = 46.2 bits (108), Expect = 1e-04
Identities = 43/181 (23%), Positives = 78/181 (43%), Gaps = 32/181 (17%)
Query: 372 VPLDSILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYRVTAQQQLEVLLSRQRDGKHQT 431
V + +L D V +++F D++++ + ++ FW E + + L R R+
Sbjct: 714 VSFERLLQDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRARE----- 768
Query: 432 NQTKGLLRAAAVGIYEQYLSEKASPRVTVDDYLVAKLADTLNHEDPTPEIFDDIQRKVYE 491
I+ ++L KA+ V +D A+LAD + P P++F + Q +++
Sbjct: 769 -------------IFSKFLCSKATTPVNIDSQ--AQLADDVLRA-PHPDMFKEQQLQIFN 812
Query: 492 LMLRDERFYPSFRQNALYVR-MLAELDMLKDPSFRGSDDGDGESFNGSPTGSINLSLDDL 550
LM D Y F ++ LY +LAE++ G D + SP +L D
Sbjct: 813 LMKFDS--YTRFLKSPLYQECILAEVE--------GRALPDSQQVPSSPASKHSLGSDHS 862
Query: 551 S 551
S
Sbjct: 863 S 863
>gi|38327601 regulator of G-protein signalling 12 isoform 1 [Homo
sapiens]
Length = 1447
Score = 46.2 bits (108), Expect = 1e-04
Identities = 43/181 (23%), Positives = 78/181 (43%), Gaps = 32/181 (17%)
Query: 372 VPLDSILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYRVTAQQQLEVLLSRQRDGKHQT 431
V + +L D V +++F D++++ + ++ FW E + + L R R+
Sbjct: 714 VSFERLLQDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRARE----- 768
Query: 432 NQTKGLLRAAAVGIYEQYLSEKASPRVTVDDYLVAKLADTLNHEDPTPEIFDDIQRKVYE 491
I+ ++L KA+ V +D A+LAD + P P++F + Q +++
Sbjct: 769 -------------IFSKFLCSKATTPVNIDSQ--AQLADDVLRA-PHPDMFKEQQLQIFN 812
Query: 492 LMLRDERFYPSFRQNALYVR-MLAELDMLKDPSFRGSDDGDGESFNGSPTGSINLSLDDL 550
LM D Y F ++ LY +LAE++ G D + SP +L D
Sbjct: 813 LMKFDS--YTRFLKSPLYQECILAEVE--------GRALPDSQQVPSSPASKHSLGSDHS 862
Query: 551 S 551
S
Sbjct: 863 S 863
>gi|38327599 regulator of G-protein signalling 12 isoform 3 [Homo
sapiens]
Length = 799
Score = 46.2 bits (108), Expect = 1e-04
Identities = 43/181 (23%), Positives = 78/181 (43%), Gaps = 32/181 (17%)
Query: 372 VPLDSILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYRVTAQQQLEVLLSRQRDGKHQT 431
V + +L D V +++F D++++ + ++ FW E + + L R R+
Sbjct: 66 VSFERLLQDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRARE----- 120
Query: 432 NQTKGLLRAAAVGIYEQYLSEKASPRVTVDDYLVAKLADTLNHEDPTPEIFDDIQRKVYE 491
I+ ++L KA+ V +D A+LAD + P P++F + Q +++
Sbjct: 121 -------------IFSKFLCSKATTPVNIDSQ--AQLADDVLRA-PHPDMFKEQQLQIFN 164
Query: 492 LMLRDERFYPSFRQNALYVR-MLAELDMLKDPSFRGSDDGDGESFNGSPTGSINLSLDDL 550
LM D Y F ++ LY +LAE++ G D + SP +L D
Sbjct: 165 LMKFDS--YTRFLKSPLYQECILAEVE--------GRALPDSQQVPSSPASKHSLGSDHS 214
Query: 551 S 551
S
Sbjct: 215 S 215
>gi|21493033 A-kinase anchor protein 10 precursor [Homo sapiens]
Length = 662
Score = 45.8 bits (107), Expect = 2e-04
Identities = 63/248 (25%), Positives = 103/248 (41%), Gaps = 37/248 (14%)
Query: 371 TVPLDSILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYRVTAQQQLEVLLSRQRDGKHQ 430
TV L IL AL +F +YM++ L FW+ + + Q QL Q DG+
Sbjct: 377 TVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNF----QSQL-AAKKGQYDGQEA 431
Query: 431 TNQTKGLLRAAAVGIYEQYLSEKASPRVTVDDYLVAKLADTLNHE-DPTPEIFDDIQRKV 489
N A+ +Y++Y S +A+ + DD + ++ + E P P F R+
Sbjct: 432 QND--------AMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQA 483
Query: 490 YELMLRDERFYPSFRQNALYVRMLAELDMLKDPSFRGSDDGDGESFNGSPTGSINLSLDD 549
+ M ++ F P F + LY + L +L S RG + G N S T ++ D
Sbjct: 484 WTTM--EKVFLPGFLSSNLYYKYLNDL----IHSVRGDEFLGG---NVSLTAPGSVGPPD 534
Query: 550 LSNVSSDDSVQLHAYISDTGVCNDHGKTYALY--AITVHRRNLNSEEMWK-------TYR 600
S+ S DS + + + K + AI V +L+ E +++ T+
Sbjct: 535 ESHPGSSDSSASQSSVKKASI-----KILKNFDEAIIVDAASLDPESLYQRTYAGKMTFG 589
Query: 601 RYSDFHDF 608
R SD F
Sbjct: 590 RVSDLGQF 597
>gi|21361405 regulator of G-protein signalling 17 [Homo sapiens]
Length = 210
Score = 45.1 bits (105), Expect = 3e-04
Identities = 35/164 (21%), Positives = 68/164 (41%), Gaps = 36/164 (21%)
Query: 348 IQRLQSGKEINTVKLAANFGKLCTVPLDSILVDNVALQFFMDYMQQTGGQAHLFFWMTVE 407
++ Q+ + + NF K+ P L F ++++ + +L FW+ E
Sbjct: 67 LEECQNPTAEEVLSWSQNFDKMMKAPAGRNL--------FREFLRTEYSEENLLFWLACE 118
Query: 408 GYRVTAQQQLEVLLSRQRDGKHQTNQTKGLLRAAAVGIYEQYLSEKASPRVTVDDYLVAK 467
+ Q K ++ A IYE Y+S + V++D ++
Sbjct: 119 DLK--------------------KEQNKKVIEEKARMIYEDYISILSPKEVSLD----SR 154
Query: 468 LADTLNHE--DPTPEIFDDIQRKVYELMLRDERFYPSFRQNALY 509
+ + +N DP P +++D Q ++Y LM RD +P F + +Y
Sbjct: 155 VREVINRNLLDPNPHMYEDAQLQIYTLMHRDS--FPRFLNSQIY 196
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 45.1 bits (105), Expect = 3e-04
Identities = 22/73 (30%), Positives = 38/73 (52%), Gaps = 1/73 (1%)
Query: 593 EEMWKTYRRYSDFHDFHMRITEQFESLSSILKLPGKKTFNNMDRDFLEKRKKDLNAYLQL 652
+E W +RRYS F + H + ++ L++ L+ P KK F N D + +R+ L YL+
Sbjct: 1212 DETWTVFRRYSRFREMHKTLKLKYAELAA-LEFPPKKLFGNKDERVIAERRSHLEKYLRD 1270
Query: 653 LLAPEMMKASPAL 665
+ + A+ L
Sbjct: 1271 FFSVMLQSATSPL 1283
>gi|23111036 sorting nexin 1 isoform c [Homo sapiens]
Length = 474
Score = 43.1 bits (100), Expect = 0.001
Identities = 36/148 (24%), Positives = 60/148 (40%), Gaps = 16/148 (10%)
Query: 548 DDLSNVSSDDSVQLHAYISDTGVCNDHGKTYALYAITVHRR-NLNSEEMWKTYRRYSDFH 606
++L +D L I+D D Y Y +T L + + RR+SDF
Sbjct: 132 EELEEEEQEDQFDLTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFL 191
Query: 607 DFHMRITEQFESLSSILKLPGKKTFNNMDR-----------DFLEKRKKDLNAYLQLLLA 655
+ +++E+ I+ P +K+ M + +FLEKR+ L YLQ ++
Sbjct: 192 GLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVN 251
Query: 656 PEMMKASPALAHYVYDFLENKAYSKGKG 683
M P V +FLE + + G
Sbjct: 252 HPTMLQDPD----VREFLEKEELPRAVG 275
>gi|23111034 sorting nexin 1 isoform a [Homo sapiens]
Length = 522
Score = 43.1 bits (100), Expect = 0.001
Identities = 36/148 (24%), Positives = 60/148 (40%), Gaps = 16/148 (10%)
Query: 548 DDLSNVSSDDSVQLHAYISDTGVCNDHGKTYALYAITVHRR-NLNSEEMWKTYRRYSDFH 606
++L +D L I+D D Y Y +T L + + RR+SDF
Sbjct: 132 EELEEEEQEDQFDLTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFL 191
Query: 607 DFHMRITEQFESLSSILKLPGKKTFNNMDR-----------DFLEKRKKDLNAYLQLLLA 655
+ +++E+ I+ P +K+ M + +FLEKR+ L YLQ ++
Sbjct: 192 GLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVN 251
Query: 656 PEMMKASPALAHYVYDFLENKAYSKGKG 683
M P V +FLE + + G
Sbjct: 252 HPTMLQDPD----VREFLEKEELPRAVG 275
>gi|164664488 regulator of G-protein signaling 4 isoform 3 [Homo
sapiens]
Length = 187
Score = 41.6 bits (96), Expect = 0.004
Identities = 34/184 (18%), Positives = 78/184 (42%), Gaps = 24/184 (13%)
Query: 330 IKNQINSLLFVKKVCDSRIQRLQSGKEINTVKLAANFGKLCTVPLDSILVDNVALQFFMD 389
+K+++ LL C+ + K + +++ K L++++ L F
Sbjct: 1 MKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKA 60
Query: 390 YMQQTGGQAHLFFWMTVEGYRVTAQQQLEVLLSRQRDGKHQTNQTKGLLRAAAVGIYEQY 449
+++ + ++ FW++ E Y+ ++ L A IY ++
Sbjct: 61 FLKSEYSEENIDFWISCEEYKKI--------------------KSPSKLSPKAKKIYNEF 100
Query: 450 LSEKASPRVTVDDYLVAKLADTLNHEDPTPEIFDDIQRKVYELMLRDERFYPSFRQNALY 509
+S +A+ V +D + + N +PT FD+ Q+K++ LM +D Y F ++ Y
Sbjct: 101 ISVQATKEVNLDS--CTREETSRNMLEPTITCFDEAQKKIFNLMEKDS--YRRFLKSRFY 156
Query: 510 VRML 513
+ ++
Sbjct: 157 LDLV 160
>gi|5032039 regulator of G-protein signaling 4 isoform 2 [Homo
sapiens]
Length = 205
Score = 41.6 bits (96), Expect = 0.004
Identities = 34/184 (18%), Positives = 78/184 (42%), Gaps = 24/184 (13%)
Query: 330 IKNQINSLLFVKKVCDSRIQRLQSGKEINTVKLAANFGKLCTVPLDSILVDNVALQFFMD 389
+K+++ LL C+ + K + +++ K L++++ L F
Sbjct: 19 MKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKA 78
Query: 390 YMQQTGGQAHLFFWMTVEGYRVTAQQQLEVLLSRQRDGKHQTNQTKGLLRAAAVGIYEQY 449
+++ + ++ FW++ E Y+ ++ L A IY ++
Sbjct: 79 FLKSEYSEENIDFWISCEEYKKI--------------------KSPSKLSPKAKKIYNEF 118
Query: 450 LSEKASPRVTVDDYLVAKLADTLNHEDPTPEIFDDIQRKVYELMLRDERFYPSFRQNALY 509
+S +A+ V +D + + N +PT FD+ Q+K++ LM +D Y F ++ Y
Sbjct: 119 ISVQATKEVNLDS--CTREETSRNMLEPTITCFDEAQKKIFNLMEKDS--YRRFLKSRFY 174
Query: 510 VRML 513
+ ++
Sbjct: 175 LDLV 178
>gi|156416012 regulator of G-protein signaling 4 isoform 1 [Homo
sapiens]
Length = 302
Score = 41.6 bits (96), Expect = 0.004
Identities = 34/184 (18%), Positives = 78/184 (42%), Gaps = 24/184 (13%)
Query: 330 IKNQINSLLFVKKVCDSRIQRLQSGKEINTVKLAANFGKLCTVPLDSILVDNVALQFFMD 389
+K+++ LL C+ + K + +++ K L++++ L F
Sbjct: 116 MKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKA 175
Query: 390 YMQQTGGQAHLFFWMTVEGYRVTAQQQLEVLLSRQRDGKHQTNQTKGLLRAAAVGIYEQY 449
+++ + ++ FW++ E Y+ ++ L A IY ++
Sbjct: 176 FLKSEYSEENIDFWISCEEYKKI--------------------KSPSKLSPKAKKIYNEF 215
Query: 450 LSEKASPRVTVDDYLVAKLADTLNHEDPTPEIFDDIQRKVYELMLRDERFYPSFRQNALY 509
+S +A+ V +D + + N +PT FD+ Q+K++ LM +D Y F ++ Y
Sbjct: 216 ISVQATKEVNLDS--CTREETSRNMLEPTITCFDEAQKKIFNLMEKDS--YRRFLKSRFY 271
Query: 510 VRML 513
+ ++
Sbjct: 272 LDLV 275
>gi|23397574 sorting nexin 33 [Homo sapiens]
Length = 574
Score = 41.6 bits (96), Expect = 0.004
Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Query: 599 YRRYSDFHDFHMRITEQFESLSSILKLPGKKTFNNMDRDFLEKRKKDLNAYLQLLLAPEM 658
YRRY F + R+ +F ++ S+ LP K+ + DF+EKRK+ L ++ + + +
Sbjct: 264 YRRYKHFDWLYNRLLHKF-TVISVPHLPEKQATGRFEEDFIEKRKRRLILWMDHMTSHPV 322
Query: 659 MKASPALAHYVYDFLENKAYSKGK 682
+ H++ L++K + GK
Sbjct: 323 LSQYEGFQHFL-SCLDDKQWKMGK 345
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,904,903
Number of Sequences: 37866
Number of extensions: 1474232
Number of successful extensions: 4128
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 65
Number of HSP's that attempted gapping in prelim test: 4055
Number of HSP's gapped (non-prelim): 108
length of query: 957
length of database: 18,247,518
effective HSP length: 112
effective length of query: 845
effective length of database: 14,006,526
effective search space: 11835514470
effective search space used: 11835514470
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.