Search of human proteins with 169178511

Search of human proteins with 169178511

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169178511 PREDICTED: similar to cofactor required for Sp1
transcriptional activation, subunit 8, 34kDa isoform 1 [Homo sapiens]
         (130 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169178511 PREDICTED: similar to cofactor required for Sp1 tra...   261   1e-70
gi|169178509 PREDICTED: similar to cofactor required for Sp1 tra...   231   9e-62
gi|28558979 mediator complex subunit 27 [Homo sapiens]                231   9e-62
gi|13376725 coiled-coil domain containing 92 [Homo sapiens]            30   0.41 
gi|21450808 PARK2 co-regulated-like isoform 1 [Homo sapiens]           28   1.6  
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    28   2.1  
gi|24233517 IKK interacting protein isoform 1 [Homo sapiens]           28   2.1  
gi|18641360 collectin sub-family member 12 [Homo sapiens]              28   2.7  
gi|40217788 Bardet-Biedl syndrome 12 [Homo sapiens]                    27   3.5  
gi|57863248 zinc finger, CCHC domain containing 11 isoform a [Ho...    27   3.5  
gi|57863246 zinc finger, CCHC domain containing 11 isoform b [Ho...    27   3.5  
gi|57863250 zinc finger, CCHC domain containing 11 isoform c [Ho...    27   3.5  
gi|90903231 huntingtin [Homo sapiens]                                  27   6.0  
gi|31543297 neutral sphingomyelinase (N-SMase) activation associ...    26   7.8  
gi|221625547 neutral sphingomyelinase (N-SMase) activation assoc...    26   7.8  
gi|47778940 C-type lectin, superfamily member 13 [Homo sapiens]        26   7.8  
gi|40068063 TBC1 domain family, member 22B [Homo sapiens]              26   7.8  
gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2 ...    26   7.8  

>gi|169178511 PREDICTED: similar to cofactor required for Sp1
           transcriptional activation, subunit 8, 34kDa isoform 1
           [Homo sapiens]
          Length = 130

 Score =  261 bits (667), Expect = 1e-70
 Identities = 130/130 (100%), Positives = 130/130 (100%)

Query: 1   MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNL 60
           MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNL
Sbjct: 1   MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNL 60

Query: 61  HSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKKEQL 120
           HSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKKEQL
Sbjct: 61  HSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKKEQL 120

Query: 121 SIPRIFHWKV 130
           SIPRIFHWKV
Sbjct: 121 SIPRIFHWKV 130


>gi|169178509 PREDICTED: similar to cofactor required for Sp1
           transcriptional activation, subunit 8, 34kDa isoform 2
           [Homo sapiens]
          Length = 160

 Score =  231 bits (590), Expect = 9e-62
 Identities = 116/116 (100%), Positives = 116/116 (100%)

Query: 1   MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNL 60
           MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNL
Sbjct: 1   MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNL 60

Query: 61  HSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNK 116
           HSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNK
Sbjct: 61  HSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNK 116


>gi|28558979 mediator complex subunit 27 [Homo sapiens]
          Length = 311

 Score =  231 bits (590), Expect = 9e-62
 Identities = 116/116 (100%), Positives = 116/116 (100%)

Query: 1   MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNL 60
           MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNL
Sbjct: 1   MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNL 60

Query: 61  HSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNK 116
           HSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNK
Sbjct: 61  HSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNK 116


>gi|13376725 coiled-coil domain containing 92 [Homo sapiens]
          Length = 331

 Score = 30.4 bits (67), Expect = 0.41
 Identities = 18/79 (22%), Positives = 38/79 (48%)

Query: 42  KETLEGREKAFIAHFQDNLHSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKT 101
           + T++ REK ++   +   H +    +ELE+ ++ +   +         L+S     D +
Sbjct: 120 ENTIKEREKKYLEELKAKSHKLTLLSSELEQRASTIAYLTSQLHAAKKKLMSSSGTSDAS 179

Query: 102 PLYSQLLQAYKWSNKKEQL 120
           P  S +L +YK +  K++L
Sbjct: 180 PSGSPVLASYKPAPPKDKL 198


>gi|21450808 PARK2 co-regulated-like isoform 1 [Homo sapiens]
          Length = 221

 Score = 28.5 bits (62), Expect = 1.6
 Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 2/58 (3%)

Query: 50  KAFIAHFQDNLHSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQL 107
           KA + H  D +    R LN L +LS +VG    +H  H     SL  ++ K P Y  +
Sbjct: 164 KAALVHSDDEVFE--RGLNALVQLSVVVGPSLNDHLKHLLTSGSLSIIKSKIPTYCSI 219


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 28.1 bits (61), Expect = 2.1
 Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 59   NLHSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQ 109
            N++SVN ++N L  ++      S + P+ NSG  S     ++TP Y   +Q
Sbjct: 1978 NVNSVNMNMNTLNAMNGY----SMSQPMMNSGYHSNHGYMNQTPQYPMQMQ 2024


>gi|24233517 IKK interacting protein isoform 1 [Homo sapiens]
          Length = 377

 Score = 28.1 bits (61), Expect = 2.1
 Identities = 22/114 (19%), Positives = 51/114 (44%), Gaps = 2/114 (1%)

Query: 11  LEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNLHSVNRDLNEL 70
           L+  + ++S +      VS + D + D   N+E L  R ++    FQ+      R L E+
Sbjct: 107 LQEATSSMSLMTQFEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEM 166

Query: 71  ERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKKEQLSIPR 124
              +++    SE   +H+   + ++  + +  L ++ L+  + S  +   ++ R
Sbjct: 167 NINTDIF--KSEAKHIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKR 218


>gi|18641360 collectin sub-family member 12 [Homo sapiens]
          Length = 742

 Score = 27.7 bits (60), Expect = 2.7
 Identities = 19/72 (26%), Positives = 34/72 (47%), Gaps = 7/72 (9%)

Query: 4   VINVSVNLEAFSQAISAIQALRSSVSRVF-------DCLKDGMRNKETLEGREKAFIAHF 56
           + N+  +++  SQAI  I+    ++ +VF       D LK+ +++ +TL     A     
Sbjct: 220 ITNLQRSVDDTSQAIQRIKNDFQNLQQVFLQAKKDTDWLKEKVQSLQTLAANNSALAKAN 279

Query: 57  QDNLHSVNRDLN 68
            D L  +N  LN
Sbjct: 280 NDTLEDMNSQLN 291


>gi|40217788 Bardet-Biedl syndrome 12 [Homo sapiens]
          Length = 710

 Score = 27.3 bits (59), Expect = 3.5
 Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 9/90 (10%)

Query: 5   INVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQ------- 57
           I VSV  E  +     + +L   V  +FDC+ D  +    LE    +     Q       
Sbjct: 111 IIVSVMSEGLNFCSEEVVSLHVPVHNIFDCM-DSTKTFSQLETFSVSLCPFLQVPSDTDL 169

Query: 58  -DNLHSVNRDLNELERLSNLVGKPSENHPL 86
            + LH +    ++   +SNL G+P +++ L
Sbjct: 170 IEELHGLKDVASQTLTISNLSGRPLKSYEL 199


>gi|57863248 zinc finger, CCHC domain containing 11 isoform a [Homo
            sapiens]
          Length = 1645

 Score = 27.3 bits (59), Expect = 3.5
 Identities = 10/23 (43%), Positives = 15/23 (65%)

Query: 80   PSENHPLHNSGLLSLDPVQDKTP 102
            P++  P+HN GLL + P+Q   P
Sbjct: 1482 PAQYSPMHNMGLLPMHPLQIPAP 1504


>gi|57863246 zinc finger, CCHC domain containing 11 isoform b [Homo
            sapiens]
          Length = 1644

 Score = 27.3 bits (59), Expect = 3.5
 Identities = 10/23 (43%), Positives = 15/23 (65%)

Query: 80   PSENHPLHNSGLLSLDPVQDKTP 102
            P++  P+HN GLL + P+Q   P
Sbjct: 1481 PAQYSPMHNMGLLPMHPLQIPAP 1503


>gi|57863250 zinc finger, CCHC domain containing 11 isoform c [Homo
            sapiens]
          Length = 1640

 Score = 27.3 bits (59), Expect = 3.5
 Identities = 10/23 (43%), Positives = 15/23 (65%)

Query: 80   PSENHPLHNSGLLSLDPVQDKTP 102
            P++  P+HN GLL + P+Q   P
Sbjct: 1477 PAQYSPMHNMGLLPMHPLQIPAP 1499


>gi|90903231 huntingtin [Homo sapiens]
          Length = 3144

 Score = 26.6 bits (57), Expect = 6.0
 Identities = 12/41 (29%), Positives = 19/41 (46%)

Query: 80   PSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKKEQL 120
            P  +HPL   G +SL+ V      Y  L+++  W+     L
Sbjct: 2078 PVSSHPLDGDGHVSLETVSPDKDWYVHLVKSQCWTRSDSAL 2118


>gi|31543297 neutral sphingomyelinase (N-SMase) activation
           associated factor isoform 1 [Homo sapiens]
          Length = 917

 Score = 26.2 bits (56), Expect = 7.8
 Identities = 19/84 (22%), Positives = 39/84 (46%), Gaps = 7/84 (8%)

Query: 40  RNKETLEGREKAFIAHFQDNLHS-VNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQ 98
           ++K+ LE        +  ++LH  ++      ++ S+ VG  +  HPL   G + L+ +Q
Sbjct: 492 KSKDALESN------YVSEHLHEWIDLIFGYKQKGSDAVGAHNVFHPLTYEGGVDLNSIQ 545

Query: 99  DKTPLYSQLLQAYKWSNKKEQLSI 122
           D     + L Q  ++    +QL +
Sbjct: 546 DPDEKVAMLTQILEFGQTPKQLFV 569


>gi|221625547 neutral sphingomyelinase (N-SMase) activation
           associated factor isoform 2 [Homo sapiens]
          Length = 948

 Score = 26.2 bits (56), Expect = 7.8
 Identities = 19/84 (22%), Positives = 39/84 (46%), Gaps = 7/84 (8%)

Query: 40  RNKETLEGREKAFIAHFQDNLHS-VNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQ 98
           ++K+ LE        +  ++LH  ++      ++ S+ VG  +  HPL   G + L+ +Q
Sbjct: 523 KSKDALESN------YVSEHLHEWIDLIFGYKQKGSDAVGAHNVFHPLTYEGGVDLNSIQ 576

Query: 99  DKTPLYSQLLQAYKWSNKKEQLSI 122
           D     + L Q  ++    +QL +
Sbjct: 577 DPDEKVAMLTQILEFGQTPKQLFV 600


>gi|47778940 C-type lectin, superfamily member 13 [Homo sapiens]
          Length = 589

 Score = 26.2 bits (56), Expect = 7.8
 Identities = 15/67 (22%), Positives = 26/67 (38%)

Query: 10  NLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNLHSVNRDLNE 69
           N+   +  I  +     + SR    LK GM+N   L  + +   ++ Q     + R   +
Sbjct: 368 NVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGD 427

Query: 70  LERLSNL 76
           LE    L
Sbjct: 428 LENTKAL 434


>gi|40068063 TBC1 domain family, member 22B [Homo sapiens]
          Length = 505

 Score = 26.2 bits (56), Expect = 7.8
 Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 1/39 (2%)

Query: 48  REKAFIAHFQDNLHSVNRDLNELERLSNLVGKPSENHPL 86
           REK  +  F+  L S N DL+EL + S   G P E  P+
Sbjct: 181 REKTRLEKFRQLLSSQNTDLDELRKCS-WPGVPREVRPI 218


>gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2
           [Homo sapiens]
          Length = 1235

 Score = 26.2 bits (56), Expect = 7.8
 Identities = 24/109 (22%), Positives = 46/109 (42%), Gaps = 8/109 (7%)

Query: 21  IQALRSSVSRVFDCLKDGMRNKETLEG---REKAFIAHFQDNLHSVNRDLNELERLSNLV 77
           I+ L        DCLK+  + +ETL     + K+ ++ F + L+ +  +L     +    
Sbjct: 435 IEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEFNEELNLIRSELQN-AGIDTHE 493

Query: 78  GKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKKEQLSIPRIF 126
           GK  +        L  L P      ++ +L       +KK QL++ ++F
Sbjct: 494 GKRQQKRAEVLEHLKRLYP----DSVFGRLFDLCHPIHKKYQLAVTKVF 538


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,518,095
Number of Sequences: 37866
Number of extensions: 182361
Number of successful extensions: 544
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 533
Number of HSP's gapped (non-prelim): 19
length of query: 130
length of database: 18,247,518
effective HSP length: 90
effective length of query: 40
effective length of database: 14,839,578
effective search space: 593583120
effective search space used: 593583120
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.