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Search of human proteins with 111154092
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
sapiens]
(748 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 1515 0.0
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa... 1308 0.0
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa... 1236 0.0
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 578 e-165
gi|55770898 Rho GTPase activating protein 25 isoform a [Homo sap... 425 e-119
gi|7661882 Rho GTPase activating protein 25 isoform b [Homo sapi... 425 e-119
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 122 2e-27
gi|54860079 nadrin isoform 1 [Homo sapiens] 117 5e-26
gi|54860105 nadrin isoform 2 [Homo sapiens] 117 5e-26
gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b ... 113 6e-25
gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a ... 113 6e-25
gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapi... 111 3e-24
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 110 5e-24
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 110 5e-24
gi|4757980 beta chimerin isoform 2 [Homo sapiens] 110 6e-24
gi|91106928 beta chimerin isoform 1 [Homo sapiens] 110 6e-24
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 107 5e-23
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 107 5e-23
gi|56119110 family with sequence similarity 13, member A1 isofor... 106 7e-23
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 106 9e-23
gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a... 105 1e-22
gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b... 105 1e-22
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 105 2e-22
gi|156071465 Rho GTPase activating protein 4 [Homo sapiens] 105 2e-22
gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens] 104 3e-22
gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens] 104 3e-22
gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens] 104 3e-22
gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapi... 104 3e-22
gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapi... 104 3e-22
gi|188497642 ARHGAP15 [Homo sapiens] 101 3e-21
>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
sapiens]
Length = 748
Score = 1515 bits (3923), Expect = 0.0
Identities = 748/748 (100%), Positives = 748/748 (100%)
Query: 1 MEENNDSTENPQQGQGRQNAIKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPL 60
MEENNDSTENPQQGQGRQNAIKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPL
Sbjct: 1 MEENNDSTENPQQGQGRQNAIKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPL 60
Query: 61 GTIFLPGNKVSEHPCNEENPGKFLFEVVPGGDRDRMTANHESYLLMASTQNDMEDWVKSI 120
GTIFLPGNKVSEHPCNEENPGKFLFEVVPGGDRDRMTANHESYLLMASTQNDMEDWVKSI
Sbjct: 61 GTIFLPGNKVSEHPCNEENPGKFLFEVVPGGDRDRMTANHESYLLMASTQNDMEDWVKSI 120
Query: 121 RRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQA 180
RRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQA
Sbjct: 121 RRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQA 180
Query: 181 NLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSK 240
NLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSK
Sbjct: 181 NLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSK 240
Query: 241 EEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPK 300
EEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPK
Sbjct: 241 EEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPK 300
Query: 301 VEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQN 360
VEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQN
Sbjct: 301 VEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQN 360
Query: 361 KENNNTKDSPSRQCSWDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMV 420
KENNNTKDSPSRQCSWDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMV
Sbjct: 361 KENNNTKDSPSRQCSWDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMV 420
Query: 421 KKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPNGSLQARRSSSLKVSGTKMGTHSVQNG 480
KKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPNGSLQARRSSSLKVSGTKMGTHSVQNG
Sbjct: 421 KKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPNGSLQARRSSSLKVSGTKMGTHSVQNG 480
Query: 481 TVRMGILNSDTLGNPTNVRNMSWLPNGYVTLRDNKQKEQAGELGQHNRLSTYDNVHQQFS 540
TVRMGILNSDTLGNPTNVRNMSWLPNGYVTLRDNKQKEQAGELGQHNRLSTYDNVHQQFS
Sbjct: 481 TVRMGILNSDTLGNPTNVRNMSWLPNGYVTLRDNKQKEQAGELGQHNRLSTYDNVHQQFS 540
Query: 541 MMNLDDKQSIDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFFGGNFEDPVLDGPPQDD 600
MMNLDDKQSIDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFFGGNFEDPVLDGPPQDD
Sbjct: 541 MMNLDDKQSIDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFFGGNFEDPVLDGPPQDD 600
Query: 601 LSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQEMTKQKI 660
LSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQEMTKQKI
Sbjct: 601 LSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQEMTKQKI 660
Query: 661 EYESRIKSLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQK 720
EYESRIKSLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQK
Sbjct: 661 EYESRIKSLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQK 720
Query: 721 EMEQFFSTFGELTVEPRRTERGNTIWIQ 748
EMEQFFSTFGELTVEPRRTERGNTIWIQ
Sbjct: 721 EMEQFFSTFGELTVEPRRTERGNTIWIQ 748
>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
sapiens]
Length = 653
Score = 1308 bits (3386), Expect = 0.0
Identities = 653/653 (100%), Positives = 653/653 (100%)
Query: 96 MTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPML 155
MTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPML
Sbjct: 1 MTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPML 60
Query: 156 VEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYL 215
VEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYL
Sbjct: 61 VEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYL 120
Query: 216 RELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQ 275
RELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQ
Sbjct: 121 RELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQ 180
Query: 276 SYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAEL 335
SYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAEL
Sbjct: 181 SYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAEL 240
Query: 336 QSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSESPQRSSMNNGSPTAL 395
QSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSESPQRSSMNNGSPTAL
Sbjct: 241 QSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSESPQRSSMNNGSPTAL 300
Query: 396 SGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPNG 455
SGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPNG
Sbjct: 301 SGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPNG 360
Query: 456 SLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNPTNVRNMSWLPNGYVTLRDNK 515
SLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNPTNVRNMSWLPNGYVTLRDNK
Sbjct: 361 SLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNPTNVRNMSWLPNGYVTLRDNK 420
Query: 516 QKEQAGELGQHNRLSTYDNVHQQFSMMNLDDKQSIDSATWSTSSCEISLPENSNSCRSST 575
QKEQAGELGQHNRLSTYDNVHQQFSMMNLDDKQSIDSATWSTSSCEISLPENSNSCRSST
Sbjct: 421 QKEQAGELGQHNRLSTYDNVHQQFSMMNLDDKQSIDSATWSTSSCEISLPENSNSCRSST 480
Query: 576 TTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVG 635
TTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVG
Sbjct: 481 TTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVG 540
Query: 636 NSSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFT 695
NSSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFT
Sbjct: 541 NSSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFT 600
Query: 696 MIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTVEPRRTERGNTIWIQ 748
MIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTVEPRRTERGNTIWIQ
Sbjct: 601 MIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTVEPRRTERGNTIWIQ 653
>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
sapiens]
Length = 655
Score = 1236 bits (3197), Expect = 0.0
Identities = 619/621 (99%), Positives = 619/621 (99%)
Query: 128 FGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQ 187
F GIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQ
Sbjct: 35 FRKGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQ 94
Query: 188 DAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVK 247
DAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVK
Sbjct: 95 DAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVK 154
Query: 248 ELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTI 307
ELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTI
Sbjct: 155 ELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTI 214
Query: 308 MEGTVVVQQLMSVMISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTK 367
MEGTVVVQQLMSVMISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTK
Sbjct: 215 MEGTVVVQQLMSVMISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTK 274
Query: 368 DSPSRQCSWDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFN 427
DSPSRQCSWDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFN
Sbjct: 275 DSPSRQCSWDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFN 334
Query: 428 KGSGIVTNGSFSSSNAEGLEKTQTTPNGSLQARRSSSLKVSGTKMGTHSVQNGTVRMGIL 487
KGSGIVTNGSFSSSNAEGLEKTQTTPNGSLQARRSSSLKVSGTKMGTHSVQNGTVRMGIL
Sbjct: 335 KGSGIVTNGSFSSSNAEGLEKTQTTPNGSLQARRSSSLKVSGTKMGTHSVQNGTVRMGIL 394
Query: 488 NSDTLGNPTNVRNMSWLPNGYVTLRDNKQKEQAGELGQHNRLSTYDNVHQQFSMMNLDDK 547
NSDTLGNPTNVRNMSWLPNGYVTLRDNKQKEQAGELGQHNRLSTYDNVHQQFSMMNLDDK
Sbjct: 395 NSDTLGNPTNVRNMSWLPNGYVTLRDNKQKEQAGELGQHNRLSTYDNVHQQFSMMNLDDK 454
Query: 548 QSIDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDY 607
QSIDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDY
Sbjct: 455 QSIDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDY 514
Query: 608 ESKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQEMTKQKIEYESRIK 667
ESKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQEMTKQKIEYESRIK
Sbjct: 515 ESKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQEMTKQKIEYESRIK 574
Query: 668 SLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFS 727
SLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFS
Sbjct: 575 SLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFS 634
Query: 728 TFGELTVEPRRTERGNTIWIQ 748
TFGELTVEPRRTERGNTIWIQ
Sbjct: 635 TFGELTVEPRRTERGNTIWIQ 655
>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
Length = 698
Score = 578 bits (1491), Expect = e-165
Identities = 344/726 (47%), Positives = 447/726 (61%), Gaps = 87/726 (11%)
Query: 21 IKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLPGNKVSEHPCNEENP 80
+K GWL+KQ +K W RWFVL+GDQL+Y+KD+DE KP G I L G +V+E P E+P
Sbjct: 39 LKAGWLKKQRSIMKNWQQRWFVLRGDQLFYYKDKDEIKPQGFISLQGTQVTELPPGPEDP 98
Query: 81 GKFLFEVVPGG--DRDRMTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLE 138
GK LFE+ PGG +R+++ AN E+ LLMAS+Q DMEDWV++IRRVIW P GGGIFGQ+LE
Sbjct: 99 GKHLFEISPGGAGEREKVPANPEALLLMASSQRDMEDWVQAIRRVIWAPLGGGIFGQRLE 158
Query: 139 DTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSF 198
+TV +E++YG RLAP+LVEQCVDFIR+RGL EEGLFR+PGQANLV++LQD+FDCGEKP F
Sbjct: 159 ETVHHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLF 218
Query: 199 DSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPV 258
DS TDVHTVASLLKLYLRELPEPV+P+A+YEDFLSCA+LL+K+E G ELAKQV +LP
Sbjct: 219 DSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQ 278
Query: 259 VNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLM 318
NYNLL+YIC+FLDEVQ+YS VNKMSVQNLATVFGPNILRP+VEDP+TIMEGT +VQ LM
Sbjct: 279 ANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLM 338
Query: 319 SVMISKHDCLFPKDA-ELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCS-- 375
+V+I KH LF E + P+ G+ QC+
Sbjct: 339 TVLIRKHSQLFTAPVPEGPTSPRGGL-----------------------------QCAVG 369
Query: 376 WDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTN 435
W E + S G P L +T+S + + +SR+ P G G
Sbjct: 370 WGSEEVTRDSQGEPGGP-GLPAHRTSSLDGAAVAV-LSRTAP----------TGPG---- 413
Query: 436 GSFSSSNAEGLEKTQTTPNGSLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNP 495
S +K QT P+ R+ SL SG+ G S ++ + I++S GN
Sbjct: 414 -----SRCSPGKKVQTLPSWKSSFRQPRSL--SGSPKGGGS----SLEVPIISSG--GN- 459
Query: 496 TNVRNMSWLPNGYVTLRDNKQKEQAGEL---GQHNRLSTYDNVHQQFSMMNLDDKQSIDS 552
WL NG +LR +++ L G RLSTYDNV + + S+ S
Sbjct: 460 -------WLMNGLSSLRGHRRASSGDRLKDSGSVQRLSTYDNVPAPGLVPGI---PSVAS 509
Query: 553 ATWS-TSSCEISLPENSNSCRSSTTTCPEQDFFGGN--FEDPVLDGPPQDDLSH-PRDYE 608
WS SS E S+ + +SC T C D + D L+ P S P+ +
Sbjct: 510 MAWSGASSSESSVGGSLSSC----TACRASDSSARSSLHTDWALEPSPLPSSSEDPKSLD 565
Query: 609 SKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQEMTKQKIEYESRIKS 668
G +S + S +S T + AL LV+ L+ E+ +Q+ EYE +K
Sbjct: 566 LDHSMDEAGAGASNSEPSEPDSPT--REHARRSEALQGLVTELRAELCRQRTEYERSVKR 623
Query: 669 LEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFST 728
+E+ + L M L +ELDQE+KK+ M+EIK+RN+ERA+EDAE+RN +LQ+EME+FFST
Sbjct: 624 IEEGSADLRKRMSRLEEELDQEKKKYIMLEIKLRNSERAREDAERRNQLLQREMEEFFST 683
Query: 729 FGELTV 734
G LTV
Sbjct: 684 LGSLTV 689
>gi|55770898 Rho GTPase activating protein 25 isoform a [Homo
sapiens]
Length = 645
Score = 425 bits (1092), Expect = e-119
Identities = 264/741 (35%), Positives = 386/741 (52%), Gaps = 147/741 (19%)
Query: 7 STENPQQGQGRQNAIKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLP 66
ST NP + IK GWL+KQ VK W R+FVL+ QLYY+KDE++TKP G ++LP
Sbjct: 39 STPNPLE-----RPIKMGWLKKQRSIVKNWQQRYFVLRAQQLYYYKDEEDTKPQGCMYLP 93
Query: 67 GNKVSEHPCNEENPGKFLFEVVPGG-DRDRMTANHESYLLMASTQNDMEDWVKSIRRVIW 125
G + E N E GKF+FE++P D++RM +SY+LMAS+Q +ME+WVK +RRV
Sbjct: 94 GCTIKEIATNPEEAGKFVFEIIPASWDQNRM--GQDSYVLMASSQAEMEEWVKFLRRVAG 151
Query: 126 GPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKE 185
P G +FGQ+L++TV YE+++G L P+LVE+C +FI + G EEG+FRLPGQ NLVK+
Sbjct: 152 TPCG--VFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQ 209
Query: 186 LQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAG 245
L+DAFD GE+PSFD +TDVHTVASLLKLYLR+LPEPV+P+++YE FL C +L + +E
Sbjct: 210 LRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKA 269
Query: 246 VKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPL 305
+EL KQ+ LP NY+LL YICRFL E+Q VNKMSV NLATV G N++R KVEDP
Sbjct: 270 QQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPA 329
Query: 306 TIMEGTVVVQQLMSVMISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNN 365
IM GT +Q++M++MI H+ LFPK ++ P + N+
Sbjct: 330 VIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPP--------------------AQKND 369
Query: 366 TKDSPSRQCS--WDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMVKKN 423
K +P + S WD +E R S + + S S T SP + +
Sbjct: 370 PKKAPVARSSVGWDATED-LRISRTDSFSSMTSDSDTTSPTGQ--------------QPS 414
Query: 424 PAFNKGSGIVTNGSFSSSNAEGLEKTQTTPN------GSLQARRSSSLKVSGTKMGTHSV 477
AF + S V + ++TQT PN + Q SS +++
Sbjct: 415 DAFPEDSSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEI---------- 464
Query: 478 QNGTVRMGILNSDTLGNPTNVRNMSWLPNGYVTLRDNKQKEQAGELGQ---HNRLSTYDN 534
+N W P+ + ++ + +L Q R STYDN
Sbjct: 465 --------------------FKNEFWSPSSEAKAGEGHRRTMSQDLRQLSDSQRTSTYDN 504
Query: 535 VHQQFSMMNLDDKQSIDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFFGGNFEDPVLD 594
V +L +++ S+ +C
Sbjct: 505 V------PSLPGSPGEEASALSSQAC---------------------------------- 524
Query: 595 GPPQDDLSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQE 654
+SK D + A+ +S+ + +L +V L++E
Sbjct: 525 -------------DSKGD--------TLASPNSETGPGKKNSGEEEIDSLQRMVQELRKE 563
Query: 655 MTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKR 714
+ QK YE +IK+LE+ N + +++ L++EL++E+KK +EI +RN ER++ED EKR
Sbjct: 564 IETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAALEISLRNMERSREDVEKR 623
Query: 715 NDMLQKEMEQFFSTFGELTVE 735
N L++E+++F + E E
Sbjct: 624 NKALEEEVKEFVKSMKEPKTE 644
>gi|7661882 Rho GTPase activating protein 25 isoform b [Homo
sapiens]
Length = 638
Score = 425 bits (1092), Expect = e-119
Identities = 264/741 (35%), Positives = 386/741 (52%), Gaps = 147/741 (19%)
Query: 7 STENPQQGQGRQNAIKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLP 66
ST NP + IK GWL+KQ VK W R+FVL+ QLYY+KDE++TKP G ++LP
Sbjct: 32 STPNPLE-----RPIKMGWLKKQRSIVKNWQQRYFVLRAQQLYYYKDEEDTKPQGCMYLP 86
Query: 67 GNKVSEHPCNEENPGKFLFEVVPGG-DRDRMTANHESYLLMASTQNDMEDWVKSIRRVIW 125
G + E N E GKF+FE++P D++RM +SY+LMAS+Q +ME+WVK +RRV
Sbjct: 87 GCTIKEIATNPEEAGKFVFEIIPASWDQNRM--GQDSYVLMASSQAEMEEWVKFLRRVAG 144
Query: 126 GPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKE 185
P G +FGQ+L++TV YE+++G L P+LVE+C +FI + G EEG+FRLPGQ NLVK+
Sbjct: 145 TPCG--VFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQ 202
Query: 186 LQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAG 245
L+DAFD GE+PSFD +TDVHTVASLLKLYLR+LPEPV+P+++YE FL C +L + +E
Sbjct: 203 LRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKA 262
Query: 246 VKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPL 305
+EL KQ+ LP NY+LL YICRFL E+Q VNKMSV NLATV G N++R KVEDP
Sbjct: 263 QQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPA 322
Query: 306 TIMEGTVVVQQLMSVMISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNN 365
IM GT +Q++M++MI H+ LFPK ++ P + N+
Sbjct: 323 VIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPP--------------------AQKND 362
Query: 366 TKDSPSRQCS--WDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMVKKN 423
K +P + S WD +E R S + + S S T SP + +
Sbjct: 363 PKKAPVARSSVGWDATED-LRISRTDSFSSMTSDSDTTSPTGQ--------------QPS 407
Query: 424 PAFNKGSGIVTNGSFSSSNAEGLEKTQTTPN------GSLQARRSSSLKVSGTKMGTHSV 477
AF + S V + ++TQT PN + Q SS +++
Sbjct: 408 DAFPEDSSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEI---------- 457
Query: 478 QNGTVRMGILNSDTLGNPTNVRNMSWLPNGYVTLRDNKQKEQAGELGQ---HNRLSTYDN 534
+N W P+ + ++ + +L Q R STYDN
Sbjct: 458 --------------------FKNEFWSPSSEAKAGEGHRRTMSQDLRQLSDSQRTSTYDN 497
Query: 535 VHQQFSMMNLDDKQSIDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFFGGNFEDPVLD 594
V +L +++ S+ +C
Sbjct: 498 V------PSLPGSPGEEASALSSQAC---------------------------------- 517
Query: 595 GPPQDDLSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQE 654
+SK D + A+ +S+ + +L +V L++E
Sbjct: 518 -------------DSKGD--------TLASPNSETGPGKKNSGEEEIDSLQRMVQELRKE 556
Query: 655 MTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKR 714
+ QK YE +IK+LE+ N + +++ L++EL++E+KK +EI +RN ER++ED EKR
Sbjct: 557 IETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAALEISLRNMERSREDVEKR 616
Query: 715 NDMLQKEMEQFFSTFGELTVE 735
N L++E+++F + E E
Sbjct: 617 NKALEEEVKEFVKSMKEPKTE 637
>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
Length = 818
Score = 122 bits (305), Expect = 2e-27
Identities = 69/204 (33%), Positives = 118/204 (57%), Gaps = 8/204 (3%)
Query: 133 FGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDC 192
FG+ LE+ + G +A +E CV + + G++EEGLFR+ A+ +K+L+ A DC
Sbjct: 253 FGKPLEEHLTIS---GREIA-FPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDC 308
Query: 193 GEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQ 252
+ + D H +A LK YLRELPEP++ + Y++++ + + +E++ ++ L
Sbjct: 309 CVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNV--QEQDKKLQALWNA 366
Query: 253 VKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTV 312
+ LP N+N ++Y+ +FL ++ Y VNKM+ N+A V GPN+L P+ E +T M TV
Sbjct: 367 CEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTV 426
Query: 313 VVQ--QLMSVMISKHDCLFPKDAE 334
+Q ++ +I D FP + E
Sbjct: 427 SLQIVGIIEPIIQHADWFFPGEIE 450
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 117 bits (292), Expect = 5e-26
Identities = 71/204 (34%), Positives = 117/204 (57%), Gaps = 8/204 (3%)
Query: 133 FGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDC 192
FG LE+ + KR G +A + +E CV + + G+KEEGLFR+ A+ +K+L+ A DC
Sbjct: 250 FGTPLEEHL---KRSGREIA-LPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDC 305
Query: 193 GEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQ 252
+ +D H VA LK YLRELPEP++ + YE++ A + ++++ +++L +
Sbjct: 306 STSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASV--QDQDKKLQDLWRT 363
Query: 253 VKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEG-- 310
+ LP N+ +Y+ +FL ++ S VNKM+ N+A V GPN+L + E L M
Sbjct: 364 CQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAAT 423
Query: 311 TVVVQQLMSVMISKHDCLFPKDAE 334
+V V ++ +I D FP++ E
Sbjct: 424 SVHVVAVIEPIIQHADWFFPEEVE 447
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 117 bits (292), Expect = 5e-26
Identities = 71/204 (34%), Positives = 117/204 (57%), Gaps = 8/204 (3%)
Query: 133 FGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDC 192
FG LE+ + KR G +A + +E CV + + G+KEEGLFR+ A+ +K+L+ A DC
Sbjct: 250 FGTPLEEHL---KRSGREIA-LPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDC 305
Query: 193 GEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQ 252
+ +D H VA LK YLRELPEP++ + YE++ A + ++++ +++L +
Sbjct: 306 STSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASV--QDQDKKLQDLWRT 363
Query: 253 VKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEG-- 310
+ LP N+ +Y+ +FL ++ S VNKM+ N+A V GPN+L + E L M
Sbjct: 364 CQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAAT 423
Query: 311 TVVVQQLMSVMISKHDCLFPKDAE 334
+V V ++ +I D FP++ E
Sbjct: 424 SVHVVAVIEPIIQHADWFFPEEVE 447
>gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b
[Homo sapiens]
Length = 1075
Score = 113 bits (283), Expect = 6e-25
Identities = 60/187 (32%), Positives = 110/187 (58%), Gaps = 8/187 (4%)
Query: 153 PMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFD--SNTDVHTVASL 210
P++VE C+ +I GL+++G+FR+PG V +++++F+ GE P D + D+++VA +
Sbjct: 496 PLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGV 555
Query: 211 LKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRF 270
LKLY R L P+ P +++D +S KL + E V ++ + + +LP V +++Y+ F
Sbjct: 556 LKLYFRGLENPLFPKERFQDLISTIKLENPAER--VHQIQQILVTLPRVVIVVMRYLFAF 613
Query: 271 LDEVQSYSGVNKMSVQNLATVFGPNILR-PKVEDPLTIMEGTVVVQQLMSVMISKHDCLF 329
L+ + YS N M NLA FGP ++ P +DP++ + +++ +I H+ +F
Sbjct: 614 LNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQ---AHINEVIKTIIIHHEAIF 670
Query: 330 PKDAELQ 336
P EL+
Sbjct: 671 PSPRELE 677
>gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a
[Homo sapiens]
Length = 1099
Score = 113 bits (283), Expect = 6e-25
Identities = 60/187 (32%), Positives = 110/187 (58%), Gaps = 8/187 (4%)
Query: 153 PMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFD--SNTDVHTVASL 210
P++VE C+ +I GL+++G+FR+PG V +++++F+ GE P D + D+++VA +
Sbjct: 520 PLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGV 579
Query: 211 LKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRF 270
LKLY R L P+ P +++D +S KL + E V ++ + + +LP V +++Y+ F
Sbjct: 580 LKLYFRGLENPLFPKERFQDLISTIKLENPAER--VHQIQQILVTLPRVVIVVMRYLFAF 637
Query: 271 LDEVQSYSGVNKMSVQNLATVFGPNILR-PKVEDPLTIMEGTVVVQQLMSVMISKHDCLF 329
L+ + YS N M NLA FGP ++ P +DP++ + +++ +I H+ +F
Sbjct: 638 LNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQ---AHINEVIKTIIIHHEAIF 694
Query: 330 PKDAELQ 336
P EL+
Sbjct: 695 PSPRELE 701
>gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo
sapiens]
Length = 1085
Score = 111 bits (277), Expect = 3e-24
Identities = 61/189 (32%), Positives = 109/189 (57%), Gaps = 8/189 (4%)
Query: 150 RLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFD--SNTDVHTV 207
++ P++VE C+ FI GL+ +G+FR+ G V +++++F+ GE P D SN D+++V
Sbjct: 517 QVIPLIVESCIRFINLYGLQHQGIFRVSGSQVEVNDIKNSFERGENPLADDQSNHDINSV 576
Query: 208 ASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYI 267
A +LKLY R L P+ P ++ D +SC ++ + E A + K + +LP +++Y+
Sbjct: 577 AGVLKLYFRGLENPLFPKERFNDLISCIRIDNLYERA--LHIRKLLLTLPRSVLIVMRYL 634
Query: 268 CRFLDEVQSYSGVNKMSVQNLATVFGPNILR-PKVEDPLTIMEGTVVVQQLMSVMISKHD 326
FL+ + YS N M NLA FGP ++ P+++D ++ V +++ +I H+
Sbjct: 635 FAFLNHLSQYSDENMMDPYNLAICFGPTLMPVPEIQDQVSCQ---AHVNEIIKTIIIHHE 691
Query: 327 CLFPKDAEL 335
+FP EL
Sbjct: 692 TIFPDAKEL 700
>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
sapiens]
Length = 521
Score = 110 bits (275), Expect = 5e-24
Identities = 64/182 (35%), Positives = 108/182 (59%), Gaps = 9/182 (4%)
Query: 153 PMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNT--DVHTVASL 210
P V+QC+ + RGL +GL+R+ G +++L+ D E+ D DVH +
Sbjct: 343 PRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGA 402
Query: 211 LKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAG-VKELAKQVKSLPVVNYNLLKYICR 269
LKL+ RELPEP+ P++ + F++ KL + + V++L V+SLP N++ L+ + +
Sbjct: 403 LKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDL---VRSLPAPNHDTLRMLFQ 459
Query: 270 FLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQ-QLMSVMISKHDCL 328
L V + N+MSVQ++A VFGP +LRP+VE+ T M T+V Q Q++ +++ + +
Sbjct: 460 HLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEE--TSMPMTMVFQNQVVELILQQCADI 517
Query: 329 FP 330
FP
Sbjct: 518 FP 519
>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
sapiens]
Length = 548
Score = 110 bits (275), Expect = 5e-24
Identities = 64/182 (35%), Positives = 108/182 (59%), Gaps = 9/182 (4%)
Query: 153 PMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNT--DVHTVASL 210
P V+QC+ + RGL +GL+R+ G +++L+ D E+ D DVH +
Sbjct: 370 PRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGA 429
Query: 211 LKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAG-VKELAKQVKSLPVVNYNLLKYICR 269
LKL+ RELPEP+ P++ + F++ KL + + V++L V+SLP N++ L+ + +
Sbjct: 430 LKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDL---VRSLPAPNHDTLRMLFQ 486
Query: 270 FLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQ-QLMSVMISKHDCL 328
L V + N+MSVQ++A VFGP +LRP+VE+ T M T+V Q Q++ +++ + +
Sbjct: 487 HLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEE--TSMPMTMVFQNQVVELILQQCADI 544
Query: 329 FP 330
FP
Sbjct: 545 FP 546
>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
Length = 468
Score = 110 bits (274), Expect = 6e-24
Identities = 62/184 (33%), Positives = 101/184 (54%), Gaps = 5/184 (2%)
Query: 149 NRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDC-GEKPSFDSNT--DVH 205
N PM+V+ C+ I RGLK EGL+R+ G +++++ AFD GEK +N D++
Sbjct: 287 NTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDIN 346
Query: 206 TVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLK 265
+ LKLY R+LP PVI Y Y F+ AK+ + +E ++ + + + LP +Y L+
Sbjct: 347 IITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADER--LEAVHEVLMLLPPAHYETLR 404
Query: 266 YICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKH 325
Y+ L +V N M+ +NL VFGP ++RP + LT + + ++ ++I
Sbjct: 405 YLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENE 464
Query: 326 DCLF 329
D LF
Sbjct: 465 DVLF 468
>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
Length = 332
Score = 110 bits (274), Expect = 6e-24
Identities = 62/184 (33%), Positives = 101/184 (54%), Gaps = 5/184 (2%)
Query: 149 NRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDC-GEKPSFDSNT--DVH 205
N PM+V+ C+ I RGLK EGL+R+ G +++++ AFD GEK +N D++
Sbjct: 151 NTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDIN 210
Query: 206 TVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLK 265
+ LKLY R+LP PVI Y Y F+ AK+ + +E ++ + + + LP +Y L+
Sbjct: 211 IITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADER--LEAVHEVLMLLPPAHYETLR 268
Query: 266 YICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKH 325
Y+ L +V N M+ +NL VFGP ++RP + LT + + ++ ++I
Sbjct: 269 YLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENE 328
Query: 326 DCLF 329
D LF
Sbjct: 329 DVLF 332
>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
Length = 459
Score = 107 bits (266), Expect = 5e-23
Identities = 59/180 (32%), Positives = 100/180 (55%), Gaps = 5/180 (2%)
Query: 153 PMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFD-CGEKPSFDSN--TDVHTVAS 209
PM+V+ C+ I RGL EGL+R+ G ++L+++++ AFD GEK N D++ +
Sbjct: 282 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 341
Query: 210 LLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICR 269
LKLY R+LP P+I Y Y F+ AK++ +E+ ++ L + +K LP + L+Y+
Sbjct: 342 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQ--LETLHEALKLLPPAHCETLRYLMA 399
Query: 270 FLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLF 329
L V + N M+ +NL VFGP ++R D + + + ++ ++I D LF
Sbjct: 400 HLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459
>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
Length = 433
Score = 107 bits (266), Expect = 5e-23
Identities = 59/180 (32%), Positives = 100/180 (55%), Gaps = 5/180 (2%)
Query: 153 PMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFD-CGEKPSFDSN--TDVHTVAS 209
PM+V+ C+ I RGL EGL+R+ G ++L+++++ AFD GEK N D++ +
Sbjct: 256 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 315
Query: 210 LLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICR 269
LKLY R+LP P+I Y Y F+ AK++ +E+ ++ L + +K LP + L+Y+
Sbjct: 316 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQ--LETLHEALKLLPPAHCETLRYLMA 373
Query: 270 FLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLF 329
L V + N M+ +NL VFGP ++R D + + + ++ ++I D LF
Sbjct: 374 HLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 433
>gi|56119110 family with sequence similarity 13, member A1 isoform a
[Homo sapiens]
Length = 1023
Score = 106 bits (265), Expect = 7e-23
Identities = 66/179 (36%), Positives = 103/179 (57%), Gaps = 8/179 (4%)
Query: 153 PMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLK 212
P +V V+++ Q GL +EGLFR+ G +V++L+ F+ G + DV + ASLLK
Sbjct: 59 PAVVWNIVEYLTQHGLTQEGLFRVNGNVKVVEQLRLKFESGVPVELGKDGDVCSAASLLK 118
Query: 213 LYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKE--LAKQVKSLPVVNYNLLKYICRF 270
L+LRELP+ +I A F+ L ++ V+E L +K LP +Y LLKY+C+F
Sbjct: 119 LFLRELPDSLITSALQPRFIQ----LFQDGRNDVQESSLRDLIKELPDTHYCLLKYLCQF 174
Query: 271 LDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLF 329
L +V + N+M+V NLATVFGPN V L M+ + ++M+ ++ ++ LF
Sbjct: 175 LTKVAKHHVQNRMNVHNLATVFGPNCFH--VPPGLEGMKEQDLCNKIMAKILENYNTLF 231
Score = 34.3 bits (77), Expect = 0.43
Identities = 69/328 (21%), Positives = 113/328 (34%), Gaps = 54/328 (16%)
Query: 442 NAEGLEKTQTTPNGSLQARRSSSLKVSGTKMGT-HSVQNGTVRMGILNSDTLGNPTNVRN 500
N + +EK G R + S TK+ H Q+G V M LNS T +
Sbjct: 445 NTQEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDD 504
Query: 501 MSWLPNGYVTLRDNKQKEQAGELGQHNRLST--------YDNVHQQFSMMNLDDKQSI-- 550
W+ + + K E+ G QH T + QQ + D ++S
Sbjct: 505 FEWMSD------ERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVS 558
Query: 551 -----------DSATWSTSSCEISLPENSNSCRSSTTTCPEQDFFGGNFEDPVLDGPPQD 599
D W S + NS P+ G +LD D
Sbjct: 559 EVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQ----AGRLIRQLLD-EDSD 613
Query: 600 DLSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQEMTKQK 659
+ PR Y + + + S NS +F+ SS SL S ++
Sbjct: 614 PMLSPRFYAYGQSRQYLD--DTEVPPSPPNSHSFMRRRSS------SLGSYDDEQEDLTP 665
Query: 660 IEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDM-- 717
+ RI+SL+++ + D ++E+K K N E K ND+
Sbjct: 666 AQLTRRIQSLKKK-------IRKFEDRFEEEKKYRPSHSDKAANPEVLK----WTNDLAK 714
Query: 718 LQKEMEQFFSTFGELTVEPRRTERGNTI 745
++++++ E + PR +R NT+
Sbjct: 715 FRRQLKESKLKISEEDLTPRMRQRSNTL 742
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 106 bits (264), Expect = 9e-23
Identities = 67/182 (36%), Positives = 98/182 (53%), Gaps = 7/182 (3%)
Query: 156 VEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYL 215
+E CV + G+KEEGLFRL A+++K L+ + +D H VA LK YL
Sbjct: 293 IEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCSDPHAVAGALKSYL 352
Query: 216 RELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQ 275
RELPEP++ + Y+D++ A L KE A ++ L + LP N + L+Y+ +FL +
Sbjct: 353 RELPEPLMTFDLYDDWMRAASL--KEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLA 410
Query: 276 SYSGVNKMSVQNLATVFGPNILRP--KVEDPLTIMEGTVVVQQLMSV---MISKHDCLFP 330
VNKM+ N+A V GPN+L P K D + +V Q++ V +I D LFP
Sbjct: 411 EEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQSADTLFP 470
Query: 331 KD 332
D
Sbjct: 471 GD 472
>gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a
[Homo sapiens]
Length = 1071
Score = 105 bits (263), Expect = 1e-22
Identities = 64/200 (32%), Positives = 113/200 (56%), Gaps = 10/200 (5%)
Query: 140 TVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKP-SF 198
TVR K+ ++ P++VE C+ FI + GL+ EG+FR+ G V ++++AF+ GE P +
Sbjct: 494 TVR--KQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKNAFERGEDPLAG 551
Query: 199 DSNT-DVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLP 257
D N D+ ++A +LKLY R L P+ P + D ++C + + +E A + K + LP
Sbjct: 552 DQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERA--LHIRKVLLVLP 609
Query: 258 VVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILR-PKVEDPLTIMEGTVVVQQ 316
+++Y+ FL+ + +S N M NLA FGP+++ P+ D ++ V +
Sbjct: 610 KTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSCQ---AHVNE 666
Query: 317 LMSVMISKHDCLFPKDAELQ 336
L+ +I +H+ +FP EL+
Sbjct: 667 LIKTIIIQHENIFPSPRELE 686
>gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b
[Homo sapiens]
Length = 836
Score = 105 bits (263), Expect = 1e-22
Identities = 64/200 (32%), Positives = 113/200 (56%), Gaps = 10/200 (5%)
Query: 140 TVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKP-SF 198
TVR K+ ++ P++VE C+ FI + GL+ EG+FR+ G V ++++AF+ GE P +
Sbjct: 494 TVR--KQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKNAFERGEDPLAG 551
Query: 199 DSNT-DVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLP 257
D N D+ ++A +LKLY R L P+ P + D ++C + + +E A + K + LP
Sbjct: 552 DQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERA--LHIRKVLLVLP 609
Query: 258 VVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILR-PKVEDPLTIMEGTVVVQQ 316
+++Y+ FL+ + +S N M NLA FGP+++ P+ D ++ V +
Sbjct: 610 KTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSCQ---AHVNE 666
Query: 317 LMSVMISKHDCLFPKDAELQ 336
L+ +I +H+ +FP EL+
Sbjct: 667 LIKTIIIQHENIFPSPRELE 686
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 105 bits (262), Expect = 2e-22
Identities = 86/321 (26%), Positives = 145/321 (45%), Gaps = 34/321 (10%)
Query: 108 STQNDMEDWVKSIRRVIWGPF-----GGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDF 162
S D W K I ++ F G FG +L+D + NR P++V+ C
Sbjct: 1115 SPPKDKGTWRKGIPSIMRKTFEKKPTATGTFGVRLDDC---PPAHTNRYIPLIVDICCKL 1171
Query: 163 IRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKP---SFDSNTDVHTVASLLKLYLRELP 219
+ +RGL+ G++R+PG + +Q+ + G D D++ ++SLLK + R+LP
Sbjct: 1172 VEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLP 1231
Query: 220 EPVIPYAKYEDFLSCAKLLSKEEEAG-VKELAKQVKSLPVVNYNLLKYICRFLDEVQSYS 278
EP+ KY DF+ + KE+ +K L + + LP +Y LK++ L V S
Sbjct: 1232 EPLFTNDKYADFIEANR---KEDPLDRLKTLKRLIHDLPEHHYETLKFLSAHLKTVAENS 1288
Query: 279 GVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQ-QLMSVMISKHDCLF-------- 329
NKM +NLA VFGP ++R ED +T M + Q +++ +I HD F
Sbjct: 1289 EKNKMEPRNLAIVFGPTLVRTS-EDNMTHMVTHMPDQYKIVETLIQHHDWFFTEEGAEEP 1347
Query: 330 ----PKDAELQSKPQDGVSN--NNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSESPQ 383
+++ + S+P + + N + + G + ++ T DS + SW +
Sbjct: 1348 LTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPGDV---SDSATSDSTKSKGSWGSGKDQY 1404
Query: 384 RSSMNNGSPTALSGSKTNSPK 404
+ S A + K PK
Sbjct: 1405 SRELLVSSIFAAASRKRKKPK 1425
Score = 37.0 bits (84), Expect = 0.067
Identities = 31/118 (26%), Positives = 50/118 (42%), Gaps = 27/118 (22%)
Query: 19 NAIKCGWL----------RKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLPGN 68
+A K GWL ++ GG ++ W + VL+G LY +KD+ E P
Sbjct: 931 DAAKEGWLHFRPLVTDKGKRVGGSIRPWKQMYVVLRGHSLYLYKDKREQTTPSEEEQP-- 988
Query: 69 KVSEHPC-----NEENPGKFLFEVVPGGDRDRMTANHESYLLMASTQNDMEDWVKSIR 121
+S + C E K +F R+T + L A ++DM W+K+I+
Sbjct: 989 -ISVNACLIDISYSETKRKNVF---------RLTTSDCECLFQAEDRDDMLAWIKTIQ 1036
>gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]
Length = 946
Score = 105 bits (261), Expect = 2e-22
Identities = 64/181 (35%), Positives = 102/181 (56%), Gaps = 8/181 (4%)
Query: 153 PMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNT--DVHTVASL 210
P++VE C+ FI GL+ EG+FR+ G V E++DAF+ GE P + T D+ +VA +
Sbjct: 521 PLVVESCIRFINLNGLQHEGIFRVSGAQLRVSEIRDAFERGEDPLVEGCTAHDLDSVAGV 580
Query: 211 LKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRF 270
LKLY R L P+ P + + L+ ++L + E V+ +++ + LP +L+Y+ F
Sbjct: 581 LKLYFRSLEPPLFPPDLFGELLASSELEATAER--VEHVSRLLWRLPAPVLVVLRYLFTF 638
Query: 271 LDEVQSYSGVNKMSVQNLATVFGPNILR-PKVEDPLTIMEGTVVVQQLMSVMISKHDCLF 329
L+ + YS N M NLA FGP +L P +DP+ + V QL+ +I + D +F
Sbjct: 639 LNHLAQYSDENMMDPYNLAVCFGPTLLPVPAGQDPVALQGR---VNQLVQTLIVQPDRVF 695
Query: 330 P 330
P
Sbjct: 696 P 696
>gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens]
Length = 887
Score = 104 bits (260), Expect = 3e-22
Identities = 68/206 (33%), Positives = 117/206 (56%), Gaps = 11/206 (5%)
Query: 132 IFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRG-LKEEGLFRLPGQANLVKELQDAF 190
IFG L++ + + + P +V VD+I + G L+++GLF++ G A V+ L+ +
Sbjct: 20 IFGIPLDEL--QQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRY 77
Query: 191 DCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELA 250
D GE+ DV + SLL+ +L+ELPEPVIP + + + ++ + E+E G ++L
Sbjct: 78 DSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFG-RKLR 136
Query: 251 KQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNI--LRPKVEDPLTIM 308
++ LP VNY+LLK++CRFL V S+ S +LA VFGP++ + VED M
Sbjct: 137 FLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFHIYTDVED----M 191
Query: 309 EGTVVVQQLMSVMISKHDCLFPKDAE 334
+ +V ++M+ ++ + F + E
Sbjct: 192 KEQEIVSRIMAGLLENYYEFFENEEE 217
>gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens]
Length = 915
Score = 104 bits (260), Expect = 3e-22
Identities = 68/206 (33%), Positives = 117/206 (56%), Gaps = 11/206 (5%)
Query: 132 IFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRG-LKEEGLFRLPGQANLVKELQDAF 190
IFG L++ + + + P +V VD+I + G L+++GLF++ G A V+ L+ +
Sbjct: 20 IFGIPLDEL--QQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRY 77
Query: 191 DCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELA 250
D GE+ DV + SLL+ +L+ELPEPVIP + + + ++ + E+E G ++L
Sbjct: 78 DSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFG-RKLR 136
Query: 251 KQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNI--LRPKVEDPLTIM 308
++ LP VNY+LLK++CRFL V S+ S +LA VFGP++ + VED M
Sbjct: 137 FLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFHIYTDVED----M 191
Query: 309 EGTVVVQQLMSVMISKHDCLFPKDAE 334
+ +V ++M+ ++ + F + E
Sbjct: 192 KEQEIVSRIMAGLLENYYEFFENEEE 217
>gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]
Length = 555
Score = 104 bits (259), Expect = 3e-22
Identities = 60/186 (32%), Positives = 102/186 (54%), Gaps = 6/186 (3%)
Query: 144 EKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTD 203
+K G + P+L V ++R++GL+ EGLFR V+E+Q ++ G+ +FD D
Sbjct: 324 DKNQGELIPPVL-RFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGD 382
Query: 204 VHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNL 263
+H A +LK +LRELP+P++ + YE L + S G +++ ++SLP NY +
Sbjct: 383 IHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQI---LRSLPEHNYVV 439
Query: 264 LKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMIS 323
L+Y+ FL V S NKM+ NLA VFG N++ P ++ + V + ++I
Sbjct: 440 LRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWP--SQGVSSLSALVPLNMFTELLIE 497
Query: 324 KHDCLF 329
++ +F
Sbjct: 498 YYEKIF 503
>gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo
sapiens]
Length = 433
Score = 104 bits (259), Expect = 3e-22
Identities = 60/186 (32%), Positives = 102/186 (54%), Gaps = 6/186 (3%)
Query: 144 EKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTD 203
+K G + P+L V ++R++GL+ EGLFR V+E+Q ++ G+ +FD D
Sbjct: 202 DKNQGELIPPVL-RFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGD 260
Query: 204 VHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNL 263
+H A +LK +LRELP+P++ + YE L + S G +++ ++SLP NY +
Sbjct: 261 IHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQI---LRSLPEHNYVV 317
Query: 264 LKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMIS 323
L+Y+ FL V S NKM+ NLA VFG N++ P ++ + V + ++I
Sbjct: 318 LRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWP--SQGVSSLSALVPLNMFTELLIE 375
Query: 324 KHDCLF 329
++ +F
Sbjct: 376 YYEKIF 381
>gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo
sapiens]
Length = 464
Score = 104 bits (259), Expect = 3e-22
Identities = 60/186 (32%), Positives = 102/186 (54%), Gaps = 6/186 (3%)
Query: 144 EKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTD 203
+K G + P+L V ++R++GL+ EGLFR V+E+Q ++ G+ +FD D
Sbjct: 233 DKNQGELIPPVL-RFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGD 291
Query: 204 VHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNL 263
+H A +LK +LRELP+P++ + YE L + S G +++ ++SLP NY +
Sbjct: 292 IHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQI---LRSLPEHNYVV 348
Query: 264 LKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMIS 323
L+Y+ FL V S NKM+ NLA VFG N++ P ++ + V + ++I
Sbjct: 349 LRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWP--SQGVSSLSALVPLNMFTELLIE 406
Query: 324 KHDCLF 329
++ +F
Sbjct: 407 YYEKIF 412
>gi|188497642 ARHGAP15 [Homo sapiens]
Length = 475
Score = 101 bits (251), Expect = 3e-21
Identities = 59/205 (28%), Positives = 107/205 (52%), Gaps = 9/205 (4%)
Query: 132 IFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFD 191
IFG L E N P V+QC++ + +RGL +G++R+ G +++L+ +
Sbjct: 278 IFGSHLHKVCERE----NSTVPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVN 333
Query: 192 CGEKPSFDSNT--DVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKEL 249
EK + D + D+H V LK++ RELPEP+ PY+ +E F+ K ++ ++ +
Sbjct: 334 QEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIK--KQDNNTRIEAV 391
Query: 250 AKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIME 309
V+ LP N + +K + L ++ + + N MS Q+L VFGP +LR + E +
Sbjct: 392 KSLVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLRAENETGNMAIH 451
Query: 310 GTVVVQQLMSVMISKHDCLFPKDAE 334
V Q+ +M+S++ +F + +
Sbjct: 452 -MVYQNQIAELMLSEYSKIFGSEED 475
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,470,127
Number of Sequences: 37866
Number of extensions: 1393658
Number of successful extensions: 6245
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 247
Number of HSP's successfully gapped in prelim test: 264
Number of HSP's that attempted gapping in prelim test: 4978
Number of HSP's gapped (non-prelim): 1253
length of query: 748
length of database: 18,247,518
effective HSP length: 110
effective length of query: 638
effective length of database: 14,082,258
effective search space: 8984480604
effective search space used: 8984480604
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.