Guide to the Human Genome
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Search of human proteins with 111154090

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
sapiens]
         (653 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa...  1308   0.0  
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa...  1308   0.0  
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa...  1236   0.0  
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]            488   e-138
gi|55770898 Rho GTPase activating protein 25 isoform a [Homo sap...   342   6e-94
gi|7661882 Rho GTPase activating protein 25 isoform b [Homo sapi...   342   6e-94
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]       122   1e-27
gi|54860079 nadrin isoform 1 [Homo sapiens]                           117   4e-26
gi|54860105 nadrin isoform 2 [Homo sapiens]                           117   4e-26
gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b ...   113   5e-25
gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a ...   113   5e-25
gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapi...   111   2e-24
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa...   110   4e-24
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap...   110   4e-24
gi|4757980 beta chimerin isoform 2 [Homo sapiens]                     110   5e-24
gi|91106928 beta chimerin isoform 1 [Homo sapiens]                    110   5e-24
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]            107   5e-23
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]          107   5e-23
gi|56119110 family with sequence similarity 13, member A1 isofor...   106   6e-23
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]               106   8e-23
gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a...   105   1e-22
gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b...   105   1e-22
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]          105   1e-22
gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]           105   2e-22
gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens]   104   2e-22
gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens]   104   2e-22
gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]               104   3e-22
gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapi...   104   3e-22
gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapi...   104   3e-22
gi|188497642 ARHGAP15 [Homo sapiens]                                  101   2e-21

>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
           sapiens]
          Length = 653

 Score = 1308 bits (3386), Expect = 0.0
 Identities = 653/653 (100%), Positives = 653/653 (100%)

Query: 1   MTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPML 60
           MTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPML
Sbjct: 1   MTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPML 60

Query: 61  VEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYL 120
           VEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYL
Sbjct: 61  VEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYL 120

Query: 121 RELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQ 180
           RELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQ
Sbjct: 121 RELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQ 180

Query: 181 SYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAEL 240
           SYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAEL
Sbjct: 181 SYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAEL 240

Query: 241 QSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSESPQRSSMNNGSPTAL 300
           QSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSESPQRSSMNNGSPTAL
Sbjct: 241 QSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSESPQRSSMNNGSPTAL 300

Query: 301 SGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPNG 360
           SGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPNG
Sbjct: 301 SGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPNG 360

Query: 361 SLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNPTNVRNMSWLPNGYVTLRDNK 420
           SLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNPTNVRNMSWLPNGYVTLRDNK
Sbjct: 361 SLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNPTNVRNMSWLPNGYVTLRDNK 420

Query: 421 QKEQAGELGQHNRLSTYDNVHQQFSMMNLDDKQSIDSATWSTSSCEISLPENSNSCRSST 480
           QKEQAGELGQHNRLSTYDNVHQQFSMMNLDDKQSIDSATWSTSSCEISLPENSNSCRSST
Sbjct: 421 QKEQAGELGQHNRLSTYDNVHQQFSMMNLDDKQSIDSATWSTSSCEISLPENSNSCRSST 480

Query: 481 TTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVG 540
           TTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVG
Sbjct: 481 TTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVG 540

Query: 541 NSSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFT 600
           NSSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFT
Sbjct: 541 NSSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFT 600

Query: 601 MIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTVEPRRTERGNTIWIQ 653
           MIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTVEPRRTERGNTIWIQ
Sbjct: 601 MIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTVEPRRTERGNTIWIQ 653


>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
           sapiens]
          Length = 748

 Score = 1308 bits (3386), Expect = 0.0
 Identities = 653/653 (100%), Positives = 653/653 (100%)

Query: 1   MTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPML 60
           MTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPML
Sbjct: 96  MTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPML 155

Query: 61  VEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYL 120
           VEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYL
Sbjct: 156 VEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYL 215

Query: 121 RELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQ 180
           RELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQ
Sbjct: 216 RELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQ 275

Query: 181 SYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAEL 240
           SYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAEL
Sbjct: 276 SYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAEL 335

Query: 241 QSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSESPQRSSMNNGSPTAL 300
           QSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSESPQRSSMNNGSPTAL
Sbjct: 336 QSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSESPQRSSMNNGSPTAL 395

Query: 301 SGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPNG 360
           SGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPNG
Sbjct: 396 SGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPNG 455

Query: 361 SLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNPTNVRNMSWLPNGYVTLRDNK 420
           SLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNPTNVRNMSWLPNGYVTLRDNK
Sbjct: 456 SLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNPTNVRNMSWLPNGYVTLRDNK 515

Query: 421 QKEQAGELGQHNRLSTYDNVHQQFSMMNLDDKQSIDSATWSTSSCEISLPENSNSCRSST 480
           QKEQAGELGQHNRLSTYDNVHQQFSMMNLDDKQSIDSATWSTSSCEISLPENSNSCRSST
Sbjct: 516 QKEQAGELGQHNRLSTYDNVHQQFSMMNLDDKQSIDSATWSTSSCEISLPENSNSCRSST 575

Query: 481 TTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVG 540
           TTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVG
Sbjct: 576 TTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVG 635

Query: 541 NSSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFT 600
           NSSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFT
Sbjct: 636 NSSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFT 695

Query: 601 MIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTVEPRRTERGNTIWIQ 653
           MIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTVEPRRTERGNTIWIQ
Sbjct: 696 MIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTVEPRRTERGNTIWIQ 748


>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
           sapiens]
          Length = 655

 Score = 1236 bits (3197), Expect = 0.0
 Identities = 619/621 (99%), Positives = 619/621 (99%)

Query: 33  FGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQ 92
           F  GIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQ
Sbjct: 35  FRKGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQ 94

Query: 93  DAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVK 152
           DAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVK
Sbjct: 95  DAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVK 154

Query: 153 ELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTI 212
           ELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTI
Sbjct: 155 ELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTI 214

Query: 213 MEGTVVVQQLMSVMISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTK 272
           MEGTVVVQQLMSVMISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTK
Sbjct: 215 MEGTVVVQQLMSVMISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTK 274

Query: 273 DSPSRQCSWDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFN 332
           DSPSRQCSWDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFN
Sbjct: 275 DSPSRQCSWDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFN 334

Query: 333 KGSGIVTNGSFSSSNAEGLEKTQTTPNGSLQARRSSSLKVSGTKMGTHSVQNGTVRMGIL 392
           KGSGIVTNGSFSSSNAEGLEKTQTTPNGSLQARRSSSLKVSGTKMGTHSVQNGTVRMGIL
Sbjct: 335 KGSGIVTNGSFSSSNAEGLEKTQTTPNGSLQARRSSSLKVSGTKMGTHSVQNGTVRMGIL 394

Query: 393 NSDTLGNPTNVRNMSWLPNGYVTLRDNKQKEQAGELGQHNRLSTYDNVHQQFSMMNLDDK 452
           NSDTLGNPTNVRNMSWLPNGYVTLRDNKQKEQAGELGQHNRLSTYDNVHQQFSMMNLDDK
Sbjct: 395 NSDTLGNPTNVRNMSWLPNGYVTLRDNKQKEQAGELGQHNRLSTYDNVHQQFSMMNLDDK 454

Query: 453 QSIDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDY 512
           QSIDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDY
Sbjct: 455 QSIDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDY 514

Query: 513 ESKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQEMTKQKIEYESRIK 572
           ESKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQEMTKQKIEYESRIK
Sbjct: 515 ESKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQEMTKQKIEYESRIK 574

Query: 573 SLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFS 632
           SLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFS
Sbjct: 575 SLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFS 634

Query: 633 TFGELTVEPRRTERGNTIWIQ 653
           TFGELTVEPRRTERGNTIWIQ
Sbjct: 635 TFGELTVEPRRTERGNTIWIQ 655


>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
          Length = 698

 Score =  488 bits (1257), Expect = e-138
 Identities = 302/647 (46%), Positives = 390/647 (60%), Gaps = 85/647 (13%)

Query: 3   ANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVE 62
           AN E+ LLMAS+Q DMEDWV++IRRVIW P GGGIFGQ+LE+TV +E++YG RLAP+LVE
Sbjct: 118 ANPEALLLMASSQRDMEDWVQAIRRVIWAPLGGGIFGQRLEETVHHERKYGPRLAPLLVE 177

Query: 63  QCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRE 122
           QCVDFIR+RGL EEGLFR+PGQANLV++LQD+FDCGEKP FDS TDVHTVASLLKLYLRE
Sbjct: 178 QCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLRE 237

Query: 123 LPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSY 182
           LPEPV+P+A+YEDFLSCA+LL+K+E  G  ELAKQV +LP  NYNLL+YIC+FLDEVQ+Y
Sbjct: 238 LPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAY 297

Query: 183 SGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDA-ELQ 241
           S VNKMSVQNLATVFGPNILRP+VEDP+TIMEGT +VQ LM+V+I KH  LF     E  
Sbjct: 298 SNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPEGP 357

Query: 242 SKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCS--WDKSESPQRSSMNNGSPTA 299
           + P+ G+                             QC+  W   E  + S    G P  
Sbjct: 358 TSPRGGL-----------------------------QCAVGWGSEEVTRDSQGEPGGP-G 387

Query: 300 LSGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPN 359
           L   +T+S   +   + +SR+ P           G G         S     +K QT P+
Sbjct: 388 LPAHRTSSLDGAAVAV-LSRTAP----------TGPG---------SRCSPGKKVQTLPS 427

Query: 360 GSLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNPTNVRNMSWLPNGYVTLRDN 419
                R+  SL  SG+  G  S    ++ + I++S   GN        WL NG  +LR +
Sbjct: 428 WKSSFRQPRSL--SGSPKGGGS----SLEVPIISSG--GN--------WLMNGLSSLRGH 471

Query: 420 KQKEQAGEL---GQHNRLSTYDNVHQQFSMMNLDDKQSIDSATWS-TSSCEISLPENSNS 475
           ++      L   G   RLSTYDNV     +  +    S+ S  WS  SS E S+  + +S
Sbjct: 472 RRASSGDRLKDSGSVQRLSTYDNVPAPGLVPGI---PSVASMAWSGASSSESSVGGSLSS 528

Query: 476 CRSSTTTCPEQDFFGGN--FEDPVLDGPPQDDLSH-PRDYESKSDHRSVGGRSSRATSSS 532
           C    T C   D    +    D  L+  P    S  P+  +        G  +S +  S 
Sbjct: 529 C----TACRASDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSE 584

Query: 533 DNSETFVGNSSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDEL 592
            +S T     +    AL  LV+ L+ E+ +Q+ EYE  +K +E+ +  L   M  L +EL
Sbjct: 585 PDSPT--REHARRSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEEL 642

Query: 593 DQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTV 639
           DQE+KK+ M+EIK+RN+ERA+EDAE+RN +LQ+EME+FFST G LTV
Sbjct: 643 DQEKKKYIMLEIKLRNSERAREDAERRNQLLQREMEEFFSTLGSLTV 689


>gi|55770898 Rho GTPase activating protein 25 isoform a [Homo
           sapiens]
          Length = 645

 Score =  342 bits (877), Expect = 6e-94
 Identities = 220/646 (34%), Positives = 327/646 (50%), Gaps = 139/646 (21%)

Query: 6   ESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCV 65
           +SY+LMAS+Q +ME+WVK +RRV   P G  +FGQ+L++TV YE+++G  L P+LVE+C 
Sbjct: 127 DSYVLMASSQAEMEEWVKFLRRVAGTPCG--VFGQRLDETVAYEQKFGPHLVPILVEKCA 184

Query: 66  DFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPE 125
           +FI + G  EEG+FRLPGQ NLVK+L+DAFD GE+PSFD +TDVHTVASLLKLYLR+LPE
Sbjct: 185 EFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPE 244

Query: 126 PVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGV 185
           PV+P+++YE FL C +L + +E    +EL KQ+  LP  NY+LL YICRFL E+Q    V
Sbjct: 245 PVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAV 304

Query: 186 NKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAELQSKPQ 245
           NKMSV NLATV G N++R KVEDP  IM GT  +Q++M++MI  H+ LFPK  ++   P 
Sbjct: 305 NKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPP 364

Query: 246 DGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCS--WDKSESPQRSSMNNGSPTALSGS 303
                                + N+ K +P  + S  WD +E   R S  +   +  S S
Sbjct: 365 --------------------AQKNDPKKAPVARSSVGWDATED-LRISRTDSFSSMTSDS 403

Query: 304 KTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPN---- 359
            T SP                 + + AF + S  V          +  ++TQT PN    
Sbjct: 404 DTTSPTGQ--------------QPSDAFPEDSSKVPREKPGDWKMQSRKRTQTLPNRKCF 449

Query: 360 --GSLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNPTNVRNMSWLPNGYVTLR 417
              + Q   SS +++                               +N  W P+      
Sbjct: 450 LTSAFQGANSSKMEI------------------------------FKNEFWSPSSEAKAG 479

Query: 418 DNKQKEQAGELGQ---HNRLSTYDNVHQQFSMMNLDDKQSIDSATWSTSSCEISLPENSN 474
           +  ++  + +L Q     R STYDNV       +L      +++  S+ +C         
Sbjct: 480 EGHRRTMSQDLRQLSDSQRTSTYDNV------PSLPGSPGEEASALSSQAC--------- 524

Query: 475 SCRSSTTTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDYESKSDHRSVGGRSSRATSSSDN 534
                                                 +SK D        + A+ +S+ 
Sbjct: 525 --------------------------------------DSKGD--------TLASPNSET 538

Query: 535 SETFVGNSSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQ 594
                 +      +L  +V  L++E+  QK  YE +IK+LE+ N  +  +++ L++EL++
Sbjct: 539 GPGKKNSGEEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEK 598

Query: 595 ERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTVE 640
           E+KK   +EI +RN ER++ED EKRN  L++E+++F  +  E   E
Sbjct: 599 EKKKSAALEISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTE 644


>gi|7661882 Rho GTPase activating protein 25 isoform b [Homo
           sapiens]
          Length = 638

 Score =  342 bits (877), Expect = 6e-94
 Identities = 220/646 (34%), Positives = 327/646 (50%), Gaps = 139/646 (21%)

Query: 6   ESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCV 65
           +SY+LMAS+Q +ME+WVK +RRV   P G  +FGQ+L++TV YE+++G  L P+LVE+C 
Sbjct: 120 DSYVLMASSQAEMEEWVKFLRRVAGTPCG--VFGQRLDETVAYEQKFGPHLVPILVEKCA 177

Query: 66  DFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPE 125
           +FI + G  EEG+FRLPGQ NLVK+L+DAFD GE+PSFD +TDVHTVASLLKLYLR+LPE
Sbjct: 178 EFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPE 237

Query: 126 PVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGV 185
           PV+P+++YE FL C +L + +E    +EL KQ+  LP  NY+LL YICRFL E+Q    V
Sbjct: 238 PVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAV 297

Query: 186 NKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAELQSKPQ 245
           NKMSV NLATV G N++R KVEDP  IM GT  +Q++M++MI  H+ LFPK  ++   P 
Sbjct: 298 NKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPP 357

Query: 246 DGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCS--WDKSESPQRSSMNNGSPTALSGS 303
                                + N+ K +P  + S  WD +E   R S  +   +  S S
Sbjct: 358 --------------------AQKNDPKKAPVARSSVGWDATED-LRISRTDSFSSMTSDS 396

Query: 304 KTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPN---- 359
            T SP                 + + AF + S  V          +  ++TQT PN    
Sbjct: 397 DTTSPTGQ--------------QPSDAFPEDSSKVPREKPGDWKMQSRKRTQTLPNRKCF 442

Query: 360 --GSLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNPTNVRNMSWLPNGYVTLR 417
              + Q   SS +++                               +N  W P+      
Sbjct: 443 LTSAFQGANSSKMEI------------------------------FKNEFWSPSSEAKAG 472

Query: 418 DNKQKEQAGELGQ---HNRLSTYDNVHQQFSMMNLDDKQSIDSATWSTSSCEISLPENSN 474
           +  ++  + +L Q     R STYDNV       +L      +++  S+ +C         
Sbjct: 473 EGHRRTMSQDLRQLSDSQRTSTYDNV------PSLPGSPGEEASALSSQAC--------- 517

Query: 475 SCRSSTTTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDYESKSDHRSVGGRSSRATSSSDN 534
                                                 +SK D        + A+ +S+ 
Sbjct: 518 --------------------------------------DSKGD--------TLASPNSET 531

Query: 535 SETFVGNSSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQ 594
                 +      +L  +V  L++E+  QK  YE +IK+LE+ N  +  +++ L++EL++
Sbjct: 532 GPGKKNSGEEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEK 591

Query: 595 ERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTVE 640
           E+KK   +EI +RN ER++ED EKRN  L++E+++F  +  E   E
Sbjct: 592 EKKKSAALEISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTE 637


>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
          Length = 818

 Score =  122 bits (305), Expect = 1e-27
 Identities = 69/204 (33%), Positives = 118/204 (57%), Gaps = 8/204 (3%)

Query: 38  FGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDC 97
           FG+ LE+ +      G  +A   +E CV  + + G++EEGLFR+   A+ +K+L+ A DC
Sbjct: 253 FGKPLEEHLTIS---GREIA-FPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDC 308

Query: 98  GEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQ 157
                 + + D H +A  LK YLRELPEP++ +  Y++++  + +  +E++  ++ L   
Sbjct: 309 CVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNV--QEQDKKLQALWNA 366

Query: 158 VKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTV 217
            + LP  N+N ++Y+ +FL ++  Y  VNKM+  N+A V GPN+L P+ E  +T M  TV
Sbjct: 367 CEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTV 426

Query: 218 VVQ--QLMSVMISKHDCLFPKDAE 239
            +Q   ++  +I   D  FP + E
Sbjct: 427 SLQIVGIIEPIIQHADWFFPGEIE 450


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score =  117 bits (292), Expect = 4e-26
 Identities = 71/204 (34%), Positives = 117/204 (57%), Gaps = 8/204 (3%)

Query: 38  FGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDC 97
           FG  LE+ +   KR G  +A + +E CV  + + G+KEEGLFR+   A+ +K+L+ A DC
Sbjct: 250 FGTPLEEHL---KRSGREIA-LPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDC 305

Query: 98  GEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQ 157
                 +  +D H VA  LK YLRELPEP++ +  YE++   A +  ++++  +++L + 
Sbjct: 306 STSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASV--QDQDKKLQDLWRT 363

Query: 158 VKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEG-- 215
            + LP  N+   +Y+ +FL ++   S VNKM+  N+A V GPN+L  + E  L  M    
Sbjct: 364 CQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAAT 423

Query: 216 TVVVQQLMSVMISKHDCLFPKDAE 239
           +V V  ++  +I   D  FP++ E
Sbjct: 424 SVHVVAVIEPIIQHADWFFPEEVE 447


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score =  117 bits (292), Expect = 4e-26
 Identities = 71/204 (34%), Positives = 117/204 (57%), Gaps = 8/204 (3%)

Query: 38  FGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDC 97
           FG  LE+ +   KR G  +A + +E CV  + + G+KEEGLFR+   A+ +K+L+ A DC
Sbjct: 250 FGTPLEEHL---KRSGREIA-LPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDC 305

Query: 98  GEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQ 157
                 +  +D H VA  LK YLRELPEP++ +  YE++   A +  ++++  +++L + 
Sbjct: 306 STSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASV--QDQDKKLQDLWRT 363

Query: 158 VKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEG-- 215
            + LP  N+   +Y+ +FL ++   S VNKM+  N+A V GPN+L  + E  L  M    
Sbjct: 364 CQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAAT 423

Query: 216 TVVVQQLMSVMISKHDCLFPKDAE 239
           +V V  ++  +I   D  FP++ E
Sbjct: 424 SVHVVAVIEPIIQHADWFFPEEVE 447


>gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b
           [Homo sapiens]
          Length = 1075

 Score =  113 bits (283), Expect = 5e-25
 Identities = 60/187 (32%), Positives = 110/187 (58%), Gaps = 8/187 (4%)

Query: 58  PMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFD--SNTDVHTVASL 115
           P++VE C+ +I   GL+++G+FR+PG    V +++++F+ GE P  D  +  D+++VA +
Sbjct: 496 PLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGV 555

Query: 116 LKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRF 175
           LKLY R L  P+ P  +++D +S  KL +  E   V ++ + + +LP V   +++Y+  F
Sbjct: 556 LKLYFRGLENPLFPKERFQDLISTIKLENPAER--VHQIQQILVTLPRVVIVVMRYLFAF 613

Query: 176 LDEVQSYSGVNKMSVQNLATVFGPNILR-PKVEDPLTIMEGTVVVQQLMSVMISKHDCLF 234
           L+ +  YS  N M   NLA  FGP ++  P  +DP++       + +++  +I  H+ +F
Sbjct: 614 LNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQ---AHINEVIKTIIIHHEAIF 670

Query: 235 PKDAELQ 241
           P   EL+
Sbjct: 671 PSPRELE 677


>gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a
           [Homo sapiens]
          Length = 1099

 Score =  113 bits (283), Expect = 5e-25
 Identities = 60/187 (32%), Positives = 110/187 (58%), Gaps = 8/187 (4%)

Query: 58  PMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFD--SNTDVHTVASL 115
           P++VE C+ +I   GL+++G+FR+PG    V +++++F+ GE P  D  +  D+++VA +
Sbjct: 520 PLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGV 579

Query: 116 LKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRF 175
           LKLY R L  P+ P  +++D +S  KL +  E   V ++ + + +LP V   +++Y+  F
Sbjct: 580 LKLYFRGLENPLFPKERFQDLISTIKLENPAER--VHQIQQILVTLPRVVIVVMRYLFAF 637

Query: 176 LDEVQSYSGVNKMSVQNLATVFGPNILR-PKVEDPLTIMEGTVVVQQLMSVMISKHDCLF 234
           L+ +  YS  N M   NLA  FGP ++  P  +DP++       + +++  +I  H+ +F
Sbjct: 638 LNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQ---AHINEVIKTIIIHHEAIF 694

Query: 235 PKDAELQ 241
           P   EL+
Sbjct: 695 PSPRELE 701


>gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo
           sapiens]
          Length = 1085

 Score =  111 bits (277), Expect = 2e-24
 Identities = 61/189 (32%), Positives = 109/189 (57%), Gaps = 8/189 (4%)

Query: 55  RLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFD--SNTDVHTV 112
           ++ P++VE C+ FI   GL+ +G+FR+ G    V +++++F+ GE P  D  SN D+++V
Sbjct: 517 QVIPLIVESCIRFINLYGLQHQGIFRVSGSQVEVNDIKNSFERGENPLADDQSNHDINSV 576

Query: 113 ASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYI 172
           A +LKLY R L  P+ P  ++ D +SC ++ +  E A    + K + +LP     +++Y+
Sbjct: 577 AGVLKLYFRGLENPLFPKERFNDLISCIRIDNLYERA--LHIRKLLLTLPRSVLIVMRYL 634

Query: 173 CRFLDEVQSYSGVNKMSVQNLATVFGPNILR-PKVEDPLTIMEGTVVVQQLMSVMISKHD 231
             FL+ +  YS  N M   NLA  FGP ++  P+++D ++       V +++  +I  H+
Sbjct: 635 FAFLNHLSQYSDENMMDPYNLAICFGPTLMPVPEIQDQVSCQ---AHVNEIIKTIIIHHE 691

Query: 232 CLFPKDAEL 240
            +FP   EL
Sbjct: 692 TIFPDAKEL 700


>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
           sapiens]
          Length = 521

 Score =  110 bits (275), Expect = 4e-24
 Identities = 64/182 (35%), Positives = 108/182 (59%), Gaps = 9/182 (4%)

Query: 58  PMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNT--DVHTVASL 115
           P  V+QC+  +  RGL  +GL+R+ G    +++L+   D  E+   D     DVH +   
Sbjct: 343 PRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGA 402

Query: 116 LKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAG-VKELAKQVKSLPVVNYNLLKYICR 174
           LKL+ RELPEP+ P++ +  F++  KL  +   +  V++L   V+SLP  N++ L+ + +
Sbjct: 403 LKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDL---VRSLPAPNHDTLRMLFQ 459

Query: 175 FLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQ-QLMSVMISKHDCL 233
            L  V  +   N+MSVQ++A VFGP +LRP+VE+  T M  T+V Q Q++ +++ +   +
Sbjct: 460 HLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEE--TSMPMTMVFQNQVVELILQQCADI 517

Query: 234 FP 235
           FP
Sbjct: 518 FP 519


>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
           sapiens]
          Length = 548

 Score =  110 bits (275), Expect = 4e-24
 Identities = 64/182 (35%), Positives = 108/182 (59%), Gaps = 9/182 (4%)

Query: 58  PMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNT--DVHTVASL 115
           P  V+QC+  +  RGL  +GL+R+ G    +++L+   D  E+   D     DVH +   
Sbjct: 370 PRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGA 429

Query: 116 LKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAG-VKELAKQVKSLPVVNYNLLKYICR 174
           LKL+ RELPEP+ P++ +  F++  KL  +   +  V++L   V+SLP  N++ L+ + +
Sbjct: 430 LKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDL---VRSLPAPNHDTLRMLFQ 486

Query: 175 FLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQ-QLMSVMISKHDCL 233
            L  V  +   N+MSVQ++A VFGP +LRP+VE+  T M  T+V Q Q++ +++ +   +
Sbjct: 487 HLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEE--TSMPMTMVFQNQVVELILQQCADI 544

Query: 234 FP 235
           FP
Sbjct: 545 FP 546


>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
          Length = 468

 Score =  110 bits (274), Expect = 5e-24
 Identities = 62/184 (33%), Positives = 101/184 (54%), Gaps = 5/184 (2%)

Query: 54  NRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDC-GEKPSFDSNT--DVH 110
           N   PM+V+ C+  I  RGLK EGL+R+ G    +++++ AFD  GEK    +N   D++
Sbjct: 287 NTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDIN 346

Query: 111 TVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLK 170
            +   LKLY R+LP PVI Y  Y  F+  AK+ + +E   ++ + + +  LP  +Y  L+
Sbjct: 347 IITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADER--LEAVHEVLMLLPPAHYETLR 404

Query: 171 YICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKH 230
           Y+   L +V      N M+ +NL  VFGP ++RP  +  LT +      + ++ ++I   
Sbjct: 405 YLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENE 464

Query: 231 DCLF 234
           D LF
Sbjct: 465 DVLF 468


>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
          Length = 332

 Score =  110 bits (274), Expect = 5e-24
 Identities = 62/184 (33%), Positives = 101/184 (54%), Gaps = 5/184 (2%)

Query: 54  NRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDC-GEKPSFDSNT--DVH 110
           N   PM+V+ C+  I  RGLK EGL+R+ G    +++++ AFD  GEK    +N   D++
Sbjct: 151 NTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDIN 210

Query: 111 TVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLK 170
            +   LKLY R+LP PVI Y  Y  F+  AK+ + +E   ++ + + +  LP  +Y  L+
Sbjct: 211 IITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADER--LEAVHEVLMLLPPAHYETLR 268

Query: 171 YICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKH 230
           Y+   L +V      N M+ +NL  VFGP ++RP  +  LT +      + ++ ++I   
Sbjct: 269 YLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENE 328

Query: 231 DCLF 234
           D LF
Sbjct: 329 DVLF 332


>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
          Length = 459

 Score =  107 bits (266), Expect = 5e-23
 Identities = 59/180 (32%), Positives = 100/180 (55%), Gaps = 5/180 (2%)

Query: 58  PMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFD-CGEKPSFDSN--TDVHTVAS 114
           PM+V+ C+  I  RGL  EGL+R+ G ++L+++++ AFD  GEK     N   D++ +  
Sbjct: 282 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 341

Query: 115 LLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICR 174
            LKLY R+LP P+I Y  Y  F+  AK++  +E+  ++ L + +K LP  +   L+Y+  
Sbjct: 342 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQ--LETLHEALKLLPPAHCETLRYLMA 399

Query: 175 FLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLF 234
            L  V  +   N M+ +NL  VFGP ++R    D +  +      + ++ ++I   D LF
Sbjct: 400 HLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459


>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
          Length = 433

 Score =  107 bits (266), Expect = 5e-23
 Identities = 59/180 (32%), Positives = 100/180 (55%), Gaps = 5/180 (2%)

Query: 58  PMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFD-CGEKPSFDSN--TDVHTVAS 114
           PM+V+ C+  I  RGL  EGL+R+ G ++L+++++ AFD  GEK     N   D++ +  
Sbjct: 256 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 315

Query: 115 LLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICR 174
            LKLY R+LP P+I Y  Y  F+  AK++  +E+  ++ L + +K LP  +   L+Y+  
Sbjct: 316 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQ--LETLHEALKLLPPAHCETLRYLMA 373

Query: 175 FLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLF 234
            L  V  +   N M+ +NL  VFGP ++R    D +  +      + ++ ++I   D LF
Sbjct: 374 HLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 433


>gi|56119110 family with sequence similarity 13, member A1 isoform a
           [Homo sapiens]
          Length = 1023

 Score =  106 bits (265), Expect = 6e-23
 Identities = 66/179 (36%), Positives = 103/179 (57%), Gaps = 8/179 (4%)

Query: 58  PMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLK 117
           P +V   V+++ Q GL +EGLFR+ G   +V++L+  F+ G       + DV + ASLLK
Sbjct: 59  PAVVWNIVEYLTQHGLTQEGLFRVNGNVKVVEQLRLKFESGVPVELGKDGDVCSAASLLK 118

Query: 118 LYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKE--LAKQVKSLPVVNYNLLKYICRF 175
           L+LRELP+ +I  A    F+     L ++    V+E  L   +K LP  +Y LLKY+C+F
Sbjct: 119 LFLRELPDSLITSALQPRFIQ----LFQDGRNDVQESSLRDLIKELPDTHYCLLKYLCQF 174

Query: 176 LDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLF 234
           L +V  +   N+M+V NLATVFGPN     V   L  M+   +  ++M+ ++  ++ LF
Sbjct: 175 LTKVAKHHVQNRMNVHNLATVFGPNCFH--VPPGLEGMKEQDLCNKIMAKILENYNTLF 231



 Score = 34.3 bits (77), Expect = 0.37
 Identities = 69/328 (21%), Positives = 113/328 (34%), Gaps = 54/328 (16%)

Query: 347 NAEGLEKTQTTPNGSLQARRSSSLKVSGTKMGT-HSVQNGTVRMGILNSDTLGNPTNVRN 405
           N + +EK      G    R     + S TK+   H  Q+G V M  LNS      T   +
Sbjct: 445 NTQEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDD 504

Query: 406 MSWLPNGYVTLRDNKQKEQAGELGQHNRLST--------YDNVHQQFSMMNLDDKQSI-- 455
             W+ +      + K  E+ G   QH    T          +  QQ +    D ++S   
Sbjct: 505 FEWMSD------ERKGNEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQDAGDQEESFVS 558

Query: 456 -----------DSATWSTSSCEISLPENSNSCRSSTTTCPEQDFFGGNFEDPVLDGPPQD 504
                      D   W       S  +  NS        P+     G     +LD    D
Sbjct: 559 EVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQ----AGRLIRQLLD-EDSD 613

Query: 505 DLSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQEMTKQK 564
            +  PR Y      + +    +    S  NS +F+   SS      SL S   ++     
Sbjct: 614 PMLSPRFYAYGQSRQYLD--DTEVPPSPPNSHSFMRRRSS------SLGSYDDEQEDLTP 665

Query: 565 IEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDM-- 622
            +   RI+SL+++       +    D  ++E+K       K  N E  K      ND+  
Sbjct: 666 AQLTRRIQSLKKK-------IRKFEDRFEEEKKYRPSHSDKAANPEVLK----WTNDLAK 714

Query: 623 LQKEMEQFFSTFGELTVEPRRTERGNTI 650
            ++++++      E  + PR  +R NT+
Sbjct: 715 FRRQLKESKLKISEEDLTPRMRQRSNTL 742


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score =  106 bits (264), Expect = 8e-23
 Identities = 67/182 (36%), Positives = 98/182 (53%), Gaps = 7/182 (3%)

Query: 61  VEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYL 120
           +E CV  +   G+KEEGLFRL   A+++K L+           +  +D H VA  LK YL
Sbjct: 293 IEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCSDPHAVAGALKSYL 352

Query: 121 RELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQ 180
           RELPEP++ +  Y+D++  A L  KE  A ++ L +    LP  N + L+Y+ +FL  + 
Sbjct: 353 RELPEPLMTFDLYDDWMRAASL--KEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLA 410

Query: 181 SYSGVNKMSVQNLATVFGPNILRP--KVEDPLTIMEGTVVVQQLMSV---MISKHDCLFP 235
               VNKM+  N+A V GPN+L P  K  D   +   +V   Q++ V   +I   D LFP
Sbjct: 411 EEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQSADTLFP 470

Query: 236 KD 237
            D
Sbjct: 471 GD 472


>gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a
           [Homo sapiens]
          Length = 1071

 Score =  105 bits (263), Expect = 1e-22
 Identities = 64/200 (32%), Positives = 113/200 (56%), Gaps = 10/200 (5%)

Query: 45  TVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKP-SF 103
           TVR  K+  ++  P++VE C+ FI + GL+ EG+FR+ G    V ++++AF+ GE P + 
Sbjct: 494 TVR--KQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKNAFERGEDPLAG 551

Query: 104 DSNT-DVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLP 162
           D N  D+ ++A +LKLY R L  P+ P   + D ++C  + + +E A    + K +  LP
Sbjct: 552 DQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERA--LHIRKVLLVLP 609

Query: 163 VVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILR-PKVEDPLTIMEGTVVVQQ 221
                +++Y+  FL+ +  +S  N M   NLA  FGP+++  P+  D ++       V +
Sbjct: 610 KTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSCQ---AHVNE 666

Query: 222 LMSVMISKHDCLFPKDAELQ 241
           L+  +I +H+ +FP   EL+
Sbjct: 667 LIKTIIIQHENIFPSPRELE 686


>gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b
           [Homo sapiens]
          Length = 836

 Score =  105 bits (263), Expect = 1e-22
 Identities = 64/200 (32%), Positives = 113/200 (56%), Gaps = 10/200 (5%)

Query: 45  TVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKP-SF 103
           TVR  K+  ++  P++VE C+ FI + GL+ EG+FR+ G    V ++++AF+ GE P + 
Sbjct: 494 TVR--KQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKNAFERGEDPLAG 551

Query: 104 DSNT-DVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLP 162
           D N  D+ ++A +LKLY R L  P+ P   + D ++C  + + +E A    + K +  LP
Sbjct: 552 DQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERA--LHIRKVLLVLP 609

Query: 163 VVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILR-PKVEDPLTIMEGTVVVQQ 221
                +++Y+  FL+ +  +S  N M   NLA  FGP+++  P+  D ++       V +
Sbjct: 610 KTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSCQ---AHVNE 666

Query: 222 LMSVMISKHDCLFPKDAELQ 241
           L+  +I +H+ +FP   EL+
Sbjct: 667 LIKTIIIQHENIFPSPRELE 686


>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
          Length = 1958

 Score =  105 bits (262), Expect = 1e-22
 Identities = 86/321 (26%), Positives = 145/321 (45%), Gaps = 34/321 (10%)

Query: 13   STQNDMEDWVKSIRRVIWGPF-----GGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDF 67
            S   D   W K I  ++   F       G FG +L+D       + NR  P++V+ C   
Sbjct: 1115 SPPKDKGTWRKGIPSIMRKTFEKKPTATGTFGVRLDDC---PPAHTNRYIPLIVDICCKL 1171

Query: 68   IRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKP---SFDSNTDVHTVASLLKLYLRELP 124
            + +RGL+  G++R+PG    +  +Q+  + G        D   D++ ++SLLK + R+LP
Sbjct: 1172 VEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLP 1231

Query: 125  EPVIPYAKYEDFLSCAKLLSKEEEAG-VKELAKQVKSLPVVNYNLLKYICRFLDEVQSYS 183
            EP+    KY DF+   +   KE+    +K L + +  LP  +Y  LK++   L  V   S
Sbjct: 1232 EPLFTNDKYADFIEANR---KEDPLDRLKTLKRLIHDLPEHHYETLKFLSAHLKTVAENS 1288

Query: 184  GVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQ-QLMSVMISKHDCLF-------- 234
              NKM  +NLA VFGP ++R   ED +T M   +  Q +++  +I  HD  F        
Sbjct: 1289 EKNKMEPRNLAIVFGPTLVRTS-EDNMTHMVTHMPDQYKIVETLIQHHDWFFTEEGAEEP 1347

Query: 235  ----PKDAELQSKPQDGVSN--NNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSESPQ 288
                 +++ + S+P   + +   N  +   + G +    ++ T DS   + SW   +   
Sbjct: 1348 LTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPGDV---SDSATSDSTKSKGSWGSGKDQY 1404

Query: 289  RSSMNNGSPTALSGSKTNSPK 309
               +   S  A +  K   PK
Sbjct: 1405 SRELLVSSIFAAASRKRKKPK 1425


>gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]
          Length = 946

 Score =  105 bits (261), Expect = 2e-22
 Identities = 64/181 (35%), Positives = 102/181 (56%), Gaps = 8/181 (4%)

Query: 58  PMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNT--DVHTVASL 115
           P++VE C+ FI   GL+ EG+FR+ G    V E++DAF+ GE P  +  T  D+ +VA +
Sbjct: 521 PLVVESCIRFINLNGLQHEGIFRVSGAQLRVSEIRDAFERGEDPLVEGCTAHDLDSVAGV 580

Query: 116 LKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRF 175
           LKLY R L  P+ P   + + L+ ++L +  E   V+ +++ +  LP     +L+Y+  F
Sbjct: 581 LKLYFRSLEPPLFPPDLFGELLASSELEATAER--VEHVSRLLWRLPAPVLVVLRYLFTF 638

Query: 176 LDEVQSYSGVNKMSVQNLATVFGPNILR-PKVEDPLTIMEGTVVVQQLMSVMISKHDCLF 234
           L+ +  YS  N M   NLA  FGP +L  P  +DP+ +      V QL+  +I + D +F
Sbjct: 639 LNHLAQYSDENMMDPYNLAVCFGPTLLPVPAGQDPVALQGR---VNQLVQTLIVQPDRVF 695

Query: 235 P 235
           P
Sbjct: 696 P 696


>gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens]
          Length = 887

 Score =  104 bits (260), Expect = 2e-22
 Identities = 68/206 (33%), Positives = 117/206 (56%), Gaps = 11/206 (5%)

Query: 37  IFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRG-LKEEGLFRLPGQANLVKELQDAF 95
           IFG  L++    +  + +   P +V   VD+I + G L+++GLF++ G A  V+ L+  +
Sbjct: 20  IFGIPLDEL--QQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRY 77

Query: 96  DCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELA 155
           D GE+       DV +  SLL+ +L+ELPEPVIP + +   +  ++  + E+E G ++L 
Sbjct: 78  DSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFG-RKLR 136

Query: 156 KQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNI--LRPKVEDPLTIM 213
             ++ LP VNY+LLK++CRFL  V S+      S  +LA VFGP++  +   VED    M
Sbjct: 137 FLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFHIYTDVED----M 191

Query: 214 EGTVVVQQLMSVMISKHDCLFPKDAE 239
           +   +V ++M+ ++  +   F  + E
Sbjct: 192 KEQEIVSRIMAGLLENYYEFFENEEE 217


>gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens]
          Length = 915

 Score =  104 bits (260), Expect = 2e-22
 Identities = 68/206 (33%), Positives = 117/206 (56%), Gaps = 11/206 (5%)

Query: 37  IFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRG-LKEEGLFRLPGQANLVKELQDAF 95
           IFG  L++    +  + +   P +V   VD+I + G L+++GLF++ G A  V+ L+  +
Sbjct: 20  IFGIPLDEL--QQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRY 77

Query: 96  DCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELA 155
           D GE+       DV +  SLL+ +L+ELPEPVIP + +   +  ++  + E+E G ++L 
Sbjct: 78  DSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFG-RKLR 136

Query: 156 KQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNI--LRPKVEDPLTIM 213
             ++ LP VNY+LLK++CRFL  V S+      S  +LA VFGP++  +   VED    M
Sbjct: 137 FLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFHIYTDVED----M 191

Query: 214 EGTVVVQQLMSVMISKHDCLFPKDAE 239
           +   +V ++M+ ++  +   F  + E
Sbjct: 192 KEQEIVSRIMAGLLENYYEFFENEEE 217


>gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]
          Length = 555

 Score =  104 bits (259), Expect = 3e-22
 Identities = 60/186 (32%), Positives = 102/186 (54%), Gaps = 6/186 (3%)

Query: 49  EKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTD 108
           +K  G  + P+L    V ++R++GL+ EGLFR       V+E+Q  ++ G+  +FD   D
Sbjct: 324 DKNQGELIPPVL-RFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGD 382

Query: 109 VHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNL 168
           +H  A +LK +LRELP+P++ +  YE  L    + S     G +++   ++SLP  NY +
Sbjct: 383 IHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQI---LRSLPEHNYVV 439

Query: 169 LKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMIS 228
           L+Y+  FL  V   S  NKM+  NLA VFG N++ P     ++ +   V +     ++I 
Sbjct: 440 LRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWP--SQGVSSLSALVPLNMFTELLIE 497

Query: 229 KHDCLF 234
            ++ +F
Sbjct: 498 YYEKIF 503


>gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo
           sapiens]
          Length = 433

 Score =  104 bits (259), Expect = 3e-22
 Identities = 60/186 (32%), Positives = 102/186 (54%), Gaps = 6/186 (3%)

Query: 49  EKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTD 108
           +K  G  + P+L    V ++R++GL+ EGLFR       V+E+Q  ++ G+  +FD   D
Sbjct: 202 DKNQGELIPPVL-RFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGD 260

Query: 109 VHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNL 168
           +H  A +LK +LRELP+P++ +  YE  L    + S     G +++   ++SLP  NY +
Sbjct: 261 IHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQI---LRSLPEHNYVV 317

Query: 169 LKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMIS 228
           L+Y+  FL  V   S  NKM+  NLA VFG N++ P     ++ +   V +     ++I 
Sbjct: 318 LRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWP--SQGVSSLSALVPLNMFTELLIE 375

Query: 229 KHDCLF 234
            ++ +F
Sbjct: 376 YYEKIF 381


>gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo
           sapiens]
          Length = 464

 Score =  104 bits (259), Expect = 3e-22
 Identities = 60/186 (32%), Positives = 102/186 (54%), Gaps = 6/186 (3%)

Query: 49  EKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTD 108
           +K  G  + P+L    V ++R++GL+ EGLFR       V+E+Q  ++ G+  +FD   D
Sbjct: 233 DKNQGELIPPVL-RFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGD 291

Query: 109 VHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNL 168
           +H  A +LK +LRELP+P++ +  YE  L    + S     G +++   ++SLP  NY +
Sbjct: 292 IHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQI---LRSLPEHNYVV 348

Query: 169 LKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMIS 228
           L+Y+  FL  V   S  NKM+  NLA VFG N++ P     ++ +   V +     ++I 
Sbjct: 349 LRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWP--SQGVSSLSALVPLNMFTELLIE 406

Query: 229 KHDCLF 234
            ++ +F
Sbjct: 407 YYEKIF 412


>gi|188497642 ARHGAP15 [Homo sapiens]
          Length = 475

 Score =  101 bits (251), Expect = 2e-21
 Identities = 59/205 (28%), Positives = 107/205 (52%), Gaps = 9/205 (4%)

Query: 37  IFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFD 96
           IFG  L      E    N   P  V+QC++ + +RGL  +G++R+ G    +++L+   +
Sbjct: 278 IFGSHLHKVCERE----NSTVPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVN 333

Query: 97  CGEKPSFDSNT--DVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKEL 154
             EK + D +   D+H V   LK++ RELPEP+ PY+ +E F+   K   ++    ++ +
Sbjct: 334 QEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIK--KQDNNTRIEAV 391

Query: 155 AKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIME 214
              V+ LP  N + +K +   L ++ + +  N MS Q+L  VFGP +LR + E     + 
Sbjct: 392 KSLVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLRAENETGNMAIH 451

Query: 215 GTVVVQQLMSVMISKHDCLFPKDAE 239
             V   Q+  +M+S++  +F  + +
Sbjct: 452 -MVYQNQIAELMLSEYSKIFGSEED 475


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.359 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,723,809
Number of Sequences: 37866
Number of extensions: 1141214
Number of successful extensions: 5778
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 204
Number of HSP's successfully gapped in prelim test: 240
Number of HSP's that attempted gapping in prelim test: 4626
Number of HSP's gapped (non-prelim): 1137
length of query: 653
length of database: 18,247,518
effective HSP length: 109
effective length of query: 544
effective length of database: 14,120,124
effective search space: 7681347456
effective search space used: 7681347456
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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