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Search of human proteins with 111118994
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|111118994 brain-specific angiogenesis inhibitor 1 precursor
[Homo sapiens]
(1584 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [... 3286 0.0
gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens] 1413 0.0
gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens] 1158 0.0
gi|118572606 hemicentin 1 [Homo sapiens] 248 3e-65
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s... 228 5e-59
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ... 207 8e-53
gi|6912464 latrophilin 2 precursor [Homo sapiens] 193 1e-48
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo... 192 3e-48
gi|163792198 latrophilin 3 precursor [Homo sapiens] 187 5e-47
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens] 179 2e-44
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens] 179 2e-44
gi|4505737 complement factor properdin precursor [Homo sapiens] 174 5e-43
gi|223671861 complement factor properdin precursor [Homo sapiens] 174 5e-43
gi|134031945 SCO-spondin [Homo sapiens] 166 1e-40
gi|147904700 semaphorin 5A [Homo sapiens] 166 2e-40
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 165 4e-40
gi|40317628 thrombospondin 2 precursor [Homo sapiens] 160 1e-38
gi|40317626 thrombospondin 1 precursor [Homo sapiens] 158 5e-38
gi|148806925 EGF, latrophilin and seven transmembrane domain con... 158 5e-38
gi|133930786 egf-like module-containing mucin-like receptor 3 [H... 155 3e-37
gi|59710093 G-protein coupled receptor 112 [Homo sapiens] 151 6e-36
gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens] 150 9e-36
gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens] 150 9e-36
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens] 150 9e-36
gi|45433552 G protein-coupled receptor 133 [Homo sapiens] 150 1e-35
gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo sapi... 146 1e-34
gi|223556014 G-protein coupled receptor 113 isoform 2 [Homo sapi... 146 1e-34
gi|141802362 G-protein coupled receptor 113 isoform 3 [Homo sapi... 146 1e-34
gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens] 139 2e-32
gi|23397681 egf-like module containing, mucin-like, hormone rece... 136 2e-31
>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo
sapiens]
Length = 1584
Score = 3286 bits (8521), Expect = 0.0
Identities = 1584/1584 (100%), Positives = 1584/1584 (100%)
Query: 1 MRGQAAAPGPVWILAPLLLLLLLLGRRARAAAGADAGPGPEPCATLVQGKFFGYFSAAAV 60
MRGQAAAPGPVWILAPLLLLLLLLGRRARAAAGADAGPGPEPCATLVQGKFFGYFSAAAV
Sbjct: 1 MRGQAAAPGPVWILAPLLLLLLLLGRRARAAAGADAGPGPEPCATLVQGKFFGYFSAAAV 60
Query: 61 FPANASRCSWTLRNPDPRRYTLYMKVAKAPVPCSGPGRVRTYQFDSFLESTRTYLGVESF 120
FPANASRCSWTLRNPDPRRYTLYMKVAKAPVPCSGPGRVRTYQFDSFLESTRTYLGVESF
Sbjct: 61 FPANASRCSWTLRNPDPRRYTLYMKVAKAPVPCSGPGRVRTYQFDSFLESTRTYLGVESF 120
Query: 121 DEVLRLCDPSAPLAFLQASKQFLQMRRQQPPQHDGLRPRAGPPGPTDDFSVEYLVVGNRN 180
DEVLRLCDPSAPLAFLQASKQFLQMRRQQPPQHDGLRPRAGPPGPTDDFSVEYLVVGNRN
Sbjct: 121 DEVLRLCDPSAPLAFLQASKQFLQMRRQQPPQHDGLRPRAGPPGPTDDFSVEYLVVGNRN 180
Query: 181 PSRAACQMLCRWLDACLAGSRSSHPCGIMQTPCACLGGEAGGPAAGPLAPRGDVCLRDAV 240
PSRAACQMLCRWLDACLAGSRSSHPCGIMQTPCACLGGEAGGPAAGPLAPRGDVCLRDAV
Sbjct: 181 PSRAACQMLCRWLDACLAGSRSSHPCGIMQTPCACLGGEAGGPAAGPLAPRGDVCLRDAV 240
Query: 241 AGGPENCLTSLTQDRGGHGATGGWKLWSLWGECTRDCGGGLQTRTRTCLPAPGVEGGGCE 300
AGGPENCLTSLTQDRGGHGATGGWKLWSLWGECTRDCGGGLQTRTRTCLPAPGVEGGGCE
Sbjct: 241 AGGPENCLTSLTQDRGGHGATGGWKLWSLWGECTRDCGGGLQTRTRTCLPAPGVEGGGCE 300
Query: 301 GVLEEGRQCNREACGPAGRTSSRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEW 360
GVLEEGRQCNREACGPAGRTSSRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEW
Sbjct: 301 GVLEEGRQCNREACGPAGRTSSRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEW 360
Query: 361 SPWSVCSSTCGEGWQTRTRFCVSSSYSTQCSGPLREQRLCNNSAVCPVHGAWDEWSPWSL 420
SPWSVCSSTCGEGWQTRTRFCVSSSYSTQCSGPLREQRLCNNSAVCPVHGAWDEWSPWSL
Sbjct: 361 SPWSVCSSTCGEGWQTRTRFCVSSSYSTQCSGPLREQRLCNNSAVCPVHGAWDEWSPWSL 420
Query: 421 CSSTCGRGFRDRTRTCRPPQFGGNPCEGPEKQTKFCNIALCPGRAVDGNWNEWSSWSACS 480
CSSTCGRGFRDRTRTCRPPQFGGNPCEGPEKQTKFCNIALCPGRAVDGNWNEWSSWSACS
Sbjct: 421 CSSTCGRGFRDRTRTCRPPQFGGNPCEGPEKQTKFCNIALCPGRAVDGNWNEWSSWSACS 480
Query: 481 ASCSQGRQQRTRECNGPSYGGAECQGHWVETRDCFLQQCPVDGKWQAWASWGSCSVTCGA 540
ASCSQGRQQRTRECNGPSYGGAECQGHWVETRDCFLQQCPVDGKWQAWASWGSCSVTCGA
Sbjct: 481 ASCSQGRQQRTRECNGPSYGGAECQGHWVETRDCFLQQCPVDGKWQAWASWGSCSVTCGA 540
Query: 541 GSQRRERVCSGPFFGGAACQGPQDEYRQCGTQRCPEPHEICDEDNFGAVIWKETPAGEVA 600
GSQRRERVCSGPFFGGAACQGPQDEYRQCGTQRCPEPHEICDEDNFGAVIWKETPAGEVA
Sbjct: 541 GSQRRERVCSGPFFGGAACQGPQDEYRQCGTQRCPEPHEICDEDNFGAVIWKETPAGEVA 600
Query: 601 AVRCPRNATGLILRRCELDEEGIAYWEPPTYIRCVSIDYRNIQMMTREHLAKAQRGLPGE 660
AVRCPRNATGLILRRCELDEEGIAYWEPPTYIRCVSIDYRNIQMMTREHLAKAQRGLPGE
Sbjct: 601 AVRCPRNATGLILRRCELDEEGIAYWEPPTYIRCVSIDYRNIQMMTREHLAKAQRGLPGE 660
Query: 661 GVSEVIQTLVEISQDGTSYSGDLLSTIDVLRNMTEIFRRAYYSPTPGDVQNFVQILSNLL 720
GVSEVIQTLVEISQDGTSYSGDLLSTIDVLRNMTEIFRRAYYSPTPGDVQNFVQILSNLL
Sbjct: 661 GVSEVIQTLVEISQDGTSYSGDLLSTIDVLRNMTEIFRRAYYSPTPGDVQNFVQILSNLL 720
Query: 721 AEENRDKWEEAQLAGPNAKELFRLVEDFVDVIGFRMKDLRDAYQVTDNLVLSIHKLPASG 780
AEENRDKWEEAQLAGPNAKELFRLVEDFVDVIGFRMKDLRDAYQVTDNLVLSIHKLPASG
Sbjct: 721 AEENRDKWEEAQLAGPNAKELFRLVEDFVDVIGFRMKDLRDAYQVTDNLVLSIHKLPASG 780
Query: 781 ATDISFPMKGWRATGDWAKVPEDRVTVSKSVFSTGLTEADEASVFVVGTVLYRNLGSFLA 840
ATDISFPMKGWRATGDWAKVPEDRVTVSKSVFSTGLTEADEASVFVVGTVLYRNLGSFLA
Sbjct: 781 ATDISFPMKGWRATGDWAKVPEDRVTVSKSVFSTGLTEADEASVFVVGTVLYRNLGSFLA 840
Query: 841 LQRNTTVLNSKVISVTVKPPPRSLRTPLEIEFAHMYNGTTNQTCILWDETDVPSSSAPPQ 900
LQRNTTVLNSKVISVTVKPPPRSLRTPLEIEFAHMYNGTTNQTCILWDETDVPSSSAPPQ
Sbjct: 841 LQRNTTVLNSKVISVTVKPPPRSLRTPLEIEFAHMYNGTTNQTCILWDETDVPSSSAPPQ 900
Query: 901 LGPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADANMEKATLPSVTLIVGCGVSSL 960
LGPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADANMEKATLPSVTLIVGCGVSSL
Sbjct: 901 LGPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADANMEKATLPSVTLIVGCGVSSL 960
Query: 961 TLLMLVIIYVSVWRYIRSERSVILINFCLSIISSNALILIGQTQTRNKVVCTLVAAFLHF 1020
TLLMLVIIYVSVWRYIRSERSVILINFCLSIISSNALILIGQTQTRNKVVCTLVAAFLHF
Sbjct: 961 TLLMLVIIYVSVWRYIRSERSVILINFCLSIISSNALILIGQTQTRNKVVCTLVAAFLHF 1020
Query: 1021 FFLSSFCWVLTEAWQSYMAVTGHLRNRLIRKRFLCLGWGLPALVVAISVGFTKAKGYSTM 1080
FFLSSFCWVLTEAWQSYMAVTGHLRNRLIRKRFLCLGWGLPALVVAISVGFTKAKGYSTM
Sbjct: 1021 FFLSSFCWVLTEAWQSYMAVTGHLRNRLIRKRFLCLGWGLPALVVAISVGFTKAKGYSTM 1080
Query: 1081 NYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNKLVSKDGITDKKLKERAGASLWSSC 1140
NYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNKLVSKDGITDKKLKERAGASLWSSC
Sbjct: 1081 NYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNKLVSKDGITDKKLKERAGASLWSSC 1140
Query: 1141 VVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQDAVKCRVV 1200
VVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQDAVKCRVV
Sbjct: 1141 VVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQDAVKCRVV 1200
Query: 1201 DRQEEGNGDSGGSFQNGHAQLMTDFEKDVDLACRSVLNKDIAACRTATITGTLKRPSLPE 1260
DRQEEGNGDSGGSFQNGHAQLMTDFEKDVDLACRSVLNKDIAACRTATITGTLKRPSLPE
Sbjct: 1201 DRQEEGNGDSGGSFQNGHAQLMTDFEKDVDLACRSVLNKDIAACRTATITGTLKRPSLPE 1260
Query: 1261 EEKLKLAHAKGPPTNFNSLPANVSKLHLHGSPRYPGGPLPDFPNHSLTLKRDKAPKSSFV 1320
EEKLKLAHAKGPPTNFNSLPANVSKLHLHGSPRYPGGPLPDFPNHSLTLKRDKAPKSSFV
Sbjct: 1261 EEKLKLAHAKGPPTNFNSLPANVSKLHLHGSPRYPGGPLPDFPNHSLTLKRDKAPKSSFV 1320
Query: 1321 GDGDIFKKLDSELSRAQEKALDTSYVILPTATATLRPKPKEEPKYSIHIDQMPQTRLIHL 1380
GDGDIFKKLDSELSRAQEKALDTSYVILPTATATLRPKPKEEPKYSIHIDQMPQTRLIHL
Sbjct: 1321 GDGDIFKKLDSELSRAQEKALDTSYVILPTATATLRPKPKEEPKYSIHIDQMPQTRLIHL 1380
Query: 1381 STAPEASLPARSPPSRQPPSGGPPEAPPAQPPPPPPPPPPPPQQPLPPPPNLEPAPPSLG 1440
STAPEASLPARSPPSRQPPSGGPPEAPPAQPPPPPPPPPPPPQQPLPPPPNLEPAPPSLG
Sbjct: 1381 STAPEASLPARSPPSRQPPSGGPPEAPPAQPPPPPPPPPPPPQQPLPPPPNLEPAPPSLG 1440
Query: 1441 DPGEPAAHPGPSTGPSTKNENVATLSVSSLERRKSRYAELDFEKIMHTRKRHQDMFQDLN 1500
DPGEPAAHPGPSTGPSTKNENVATLSVSSLERRKSRYAELDFEKIMHTRKRHQDMFQDLN
Sbjct: 1441 DPGEPAAHPGPSTGPSTKNENVATLSVSSLERRKSRYAELDFEKIMHTRKRHQDMFQDLN 1500
Query: 1501 RKLQHAAEKDKEVLGPDSKPEKQQTPNKRPWESLRKAHGTPTWVKKELEPLQPSPLELRS 1560
RKLQHAAEKDKEVLGPDSKPEKQQTPNKRPWESLRKAHGTPTWVKKELEPLQPSPLELRS
Sbjct: 1501 RKLQHAAEKDKEVLGPDSKPEKQQTPNKRPWESLRKAHGTPTWVKKELEPLQPSPLELRS 1560
Query: 1561 VEWERSGATIPLVGQDIIDLQTEV 1584
VEWERSGATIPLVGQDIIDLQTEV
Sbjct: 1561 VEWERSGATIPLVGQDIIDLQTEV 1584
>gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens]
Length = 1522
Score = 1413 bits (3658), Expect = 0.0
Identities = 754/1586 (47%), Positives = 998/1586 (62%), Gaps = 137/1586 (8%)
Query: 43 CATLVQGKFFGYFSAAAVFPANASRCSWTLRNPDPRRYTLYMKVAKAPVPCSGPGRVRTY 102
C+TLV+G +G +S + +FP N + C+WTL NPDP +Y++Y+K +K + CS + Y
Sbjct: 30 CSTLVKGVIYGSYSVSEMFPKNFTNCTWTLENPDPTKYSIYLKFSKKDLSCSNFSLL-AY 88
Query: 103 QFDSFLESTRTYLGVESFDEVLRLCDPSAPLAFLQASKQFLQMRRQQPPQHDGLRPRAGP 162
QFD F L + +++LC+ FLQ K F+Q+RR P GL+ +
Sbjct: 89 QFDHFSHEKIKDL-LRKNHSIMQLCNSKNAFVFLQYDKNFIQIRRVFPTNFPGLQKK--- 144
Query: 163 PGPTDDFSV-EYLVVGNRNPSRAACQMLCRWLDACLAGSRS-SHPCGIMQTPCACLG--G 218
G D S E+LV+ +PS+ C +LC WL++CL + CGIM T C C G
Sbjct: 145 -GEEDQKSFFEFLVLNKVSPSQFGCHVLCTWLESCLKSENGRTESCGIMYTKCTCPQHLG 203
Query: 219 EAGGPAAGPLAPRGDVCLRDAVAGGPENCLTSLTQDRGGHGATGGWKLWSLWGECTRDCG 278
E G + + + L + V E LTQ+
Sbjct: 204 EWG------IDDQSLILLNNVVLPLNEQTEGCLTQE------------------------ 233
Query: 279 GGLQTRTRTCLPAPGVEGGGCEGVLEEGRQCNREACGPAGRTSSRSQSLRSTDARRREEL 338
LQT T+ C + E ++ +E G G + +SQ RS +R +
Sbjct: 234 --LQT-TQVC------------NLTREAKRPPKEEFGMMGDHTIKSQRPRSVHEKRVPQE 278
Query: 339 GDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFCVSSSYSTQCSGPLREQR 398
+ +F QTG+ EEWS WS CS TCG+G Q RTR CVS Y T CSGPLRE R
Sbjct: 279 QADAAKF---MAQTGESGVEEWSQWSTCSVTCGQGSQVRTRTCVSP-YGTHCSGPLRESR 334
Query: 399 LCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRDRTRTCRPPQFGGNPCEGPEKQTKFCNI 458
+CNN+A+CPVHG W+EWSPWSLCS TCGRG R RTR+C PPQ+GG PCEGPE K CNI
Sbjct: 335 VCNNTALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCTPPQYGGRPCEGPETHHKPCNI 394
Query: 459 ALCPGRAVDGNWNEWSSWSACSASCSQGRQQRTRECNGPSYGGAECQGHWVETRDCFLQQ 518
ALCP VDG W EWSSWS CS +CS G QQR+R+C ++GG+EC+G W E+R+C+ +
Sbjct: 395 ALCP---VDGQWQEWSSWSQCSVTCSNGTQQRSRQCTAAAHGGSECRGPWAESRECYNPE 451
Query: 519 CPVDGKWQAWASWGSCSVTCGAGSQRRERVCSGPFFGGAACQGPQDEYRQCGTQRCPEPH 578
C +G+W W W CS +C G +RR R C G G C+G +E R+C QRCP P+
Sbjct: 452 CTANGQWNQWGHWSGCSKSCDGGWERRIRTCQGAVITGQQCEGTGEEVRRCSEQRCPAPY 511
Query: 579 EICDEDNFGAVIWKETPAGEVAAVRCPRNATGLILRRCELDEEGIAYWEPPTYIRCVSID 638
EIC ED +++WK TPAG++A +CP NATG RRC L G+A+WE P++ RC+S +
Sbjct: 512 EICPEDYLMSMVWKRTPAGDLAFNQCPLNATGTTSRRCSLSLHGVAFWEQPSFARCISNE 571
Query: 639 YRNIQMMTREHLAKAQRGLPGEGVSEVIQTLVEISQDGTSYSGDLLSTIDVLRNMTEIFR 698
YR++Q +EHLAK QR L G+G+S+V +TL++++Q Y+GDLL ++++LRN+T+ F+
Sbjct: 572 YRHLQHSIKEHLAKGQRMLAGDGMSQVTKTLLDLTQRKNFYAGDLLMSVEILRNVTDTFK 631
Query: 699 RAYYSPTPGDVQNFVQILSNLLAEENRDKWEEAQLAGPNAKELFRLVEDFVDVIGFRMKD 758
RA Y P VQNF QI+SNLL EEN++KWE+AQ P + EL +++EDF+ ++G M D
Sbjct: 632 RASYIPASDGVQNFFQIVSNLLDEENKEKWEDAQQIYPGSIELMQVIEDFIHIVGMGMMD 691
Query: 759 LRDAYQVTDNLVLSIHKLPASGA-TDISFPMKGWRATGDWAKVPEDRVTVSKSVFS-TGL 816
+++Y +T N+V SI KLPA+ TDI+FPMKG + DWA+ EDRV + KS+F+
Sbjct: 692 FQNSYLMTGNVVASIQKLPAASVLTDINFPMKGRKGMVDWARNSEDRVVIPKSIFTPVSS 751
Query: 817 TEADEASVFVVGTVLYRNLGSFLALQRNTTVLNSKVISVTVKPPPRSLRTPLEIEFAHMY 876
E DE+SVFV+G VLY+NL L RN TV+NSK+I VT++P P++ + LEIE AH+
Sbjct: 752 KELDESSVFVLGAVLYKNLDLILPTLRNYTVINSKIIVVTIRPEPKTTDSFLEIELAHLA 811
Query: 877 NGTTNQTCILWDETDVPSSSAPPQLGPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLS 936
NGT N C+LWD++ S LG WS +GC+TV DA T+CLCDRLSTFAILAQ
Sbjct: 812 NGTLNPYCVLWDDSKTNES-----LGTWSTQGCKTVLTDASHTKCLCDRLSTFAILAQQP 866
Query: 937 ADANMEKATLPSVTLIVGCGVSSLTLLMLVIIYVSVWRYIRSERSVILINFCLSIISSNA 996
+ ME + PSVTLIVG G+S L L+ L ++Y ++WRYIRSERS+ILINFCLSIISSN
Sbjct: 867 REIIMESSGTPSVTLIVGSGLSCLALITLAVVYAALWRYIRSERSIILINFCLSIISSNI 926
Query: 997 LILIGQTQTRNKVVCTLVAAFLHFFFLSSFCWVLTEAWQSYMAVTGHLRNRLIRKRFLCL 1056
LIL+GQTQT NK +CT AFLHFFFL+SFCWVLTEAWQSYMAVTG +R RLIRKRFLCL
Sbjct: 927 LILVGQTQTHNKSICTTTTAFLHFFFLASFCWVLTEAWQSYMAVTGKIRTRLIRKRFLCL 986
Query: 1057 GWGLPALVVAISVGFTKAKGYSTMNYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNK 1116
GWGLPALVVA SVGFT+ KGY T +YCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNK
Sbjct: 987 GWGLPALVVATSVGFTRTKGYGTDHYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNK 1046
Query: 1117 LVSKDGITDKKLKERAG---------------------------------ASLWSSCVVL 1143
LVS+DGI DKKLK RAG ASLWSSCVVL
Sbjct: 1047 LVSRDGILDKKLKHRAGQMSEPHSGLTLKCAKCGVVSTTALSATTASNAMASLWSSCVVL 1106
Query: 1144 PLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQDAVKCRVVDRQ 1203
PLLALTWMSAVLA+TD+RS LFQILFAVFDSL+GFVIVMVHCILRREVQDA +CR+ + Q
Sbjct: 1107 PLLALTWMSAVLAMTDKRSILFQILFAVFDSLQGFVIVMVHCILRREVQDAFRCRLRNCQ 1166
Query: 1204 EEGNGDSGGSFQNGHAQLMTDFEKDVDLACRSVLNKDIAACRTATITGTLKRPSLPEEEK 1263
+ N DS SF NGHAQ+MTDFEKDVD+ACRSVL+KDI CR ATITGTL R SL ++E+
Sbjct: 1167 DPINADSSSSFPNGHAQIMTDFEKDVDIACRSVLHKDIGPCRAATITGTLSRISLNDDEE 1226
Query: 1264 LKLAHAKGPPTNFNSLPANVSKLHLHGSPRYPGGPLP--DFPNHSLTLKRDKAPKSSFVG 1321
K + +G ++++LP NV + P P+ + N L + + ++ ++
Sbjct: 1227 EKGTNPEG--LSYSTLPGNVISKVIIQQPTGLHMPMSMNELSNPCLKKENSELRRTVYLC 1284
Query: 1322 DGDIFKKLDSELSRAQEKALDTSYVILPTATATLRPKPKEEPKYSIHIDQMPQTRLIHLS 1381
D + D ++ QE+ +++ Y+++P ++ +P KEE K +I ++ +P RL+H
Sbjct: 1285 TDDNLRGADMDIVHPQERMMESDYIVMPRSSVNNQPSMKEESKMNIGMETLPHERLLHYK 1344
Query: 1382 TAPEASLPARSPPSRQPPSGGPPEAPPAQPPPPPPPPPPPPQQPLPPPPNLE--PAPPSL 1439
PE ++ PP +Q L P +++ P P
Sbjct: 1345 VNPEFNM----------------------NPPVMDQFNMNLEQHLAPQEHMQNLPFEPRT 1382
Query: 1440 GDPGEPAAHPGPSTGPSTKNENVATLSVSSLERRKSRYAELDFEKIMHTRKRHQDMFQDL 1499
A+ + G S ++E +T+S+SSLERRKSRY++LDFEK+MHTRKRH ++FQ+L
Sbjct: 1383 AVKNFMASELDDNAGLS-RSETGSTISMSSLERRKSRYSDLDFEKVMHTRKRHMELFQEL 1441
Query: 1500 NRKLQHAAEKDKEVLGPDSKPEKQQTPNKRPWESLRKAHGTPTWVK-KELEPLQPSPLEL 1558
N+K Q ++ +++ P++ + PNK PW++ + P + L+ LEL
Sbjct: 1442 NQKFQ-TLDRFRDI--PNTSSMENPAPNKNPWDTFKNPSEYPHYTTINVLDTEAKDALEL 1498
Query: 1559 RSVEWERSGATIPLVGQDIIDLQTEV 1584
R EWE+ +PL Q+ D QTEV
Sbjct: 1499 RPAEWEKC-LNLPLDVQE-GDFQTEV 1522
>gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens]
Length = 1585
Score = 1158 bits (2995), Expect = 0.0
Identities = 694/1699 (40%), Positives = 915/1699 (53%), Gaps = 261/1699 (15%)
Query: 16 PLLLLLLLLGRRARAAAGADAGPGPEPCATLVQGKFFGYFSAAAVFPANASRCSWTLRNP 75
PLLL ++L R A A P P C+ L G +G FS +FP AS CSWTL NP
Sbjct: 18 PLLLSVILSLRLATAF-----DPAPSACSALASGVLYGAFSLQDLFPTIASGCSWTLENP 72
Query: 76 DPRRYTLYMKVAKAPVPCSGPGRVRTYQFDSFLES--------------TRTYLGVESFD 121
DP +Y+LY++ + C+ R D +L + + +G +
Sbjct: 73 DPTKYSLYLRFNRQEQVCAHFAP-RLLPLDHYLVNFTCLRPSPEEAVAQAESEVGRPEEE 131
Query: 122 EV-----LRLCDPSAPLAFLQASKQFLQMRRQQPPQHDGLRPRAGPPGPTDDFSVEYLVV 176
E L LC S P FL K F+Q+ P PR P VE L++
Sbjct: 132 EAEAAAGLELCSGSGPFTFLHFDKNFVQLCLSAEPSE---APRLLAPAALAFRFVEVLLI 188
Query: 177 GNRNPSRAACQMLCRWLDACLAGSRSSHPCGIMQTPCACLGGEAGGPAAGPLAPRGDVCL 236
N N S+ C +LCRW + C G A G A G P G C
Sbjct: 189 NNNNSSQFTCGVLCRWSEEC---------------------GRAAGRACGFAQP-GCSCP 226
Query: 237 RDAVAGGPENCLTSLTQDRGGHGATGGWKLWSLWGECTRDCGGGLQTRTRTCLPAPGVEG 296
+A AG T G T + PG
Sbjct: 227 GEAGAGST-----------------------------TTTSPGPPAAHTLSNALVPGGPA 257
Query: 297 GGCEGVLEEGRQCNREACGPAGRTSSRSQSLRSTDARRREELGDE----------LQQFG 346
E L G S L +T+ R EE +E + G
Sbjct: 258 PPAEADLHSGS----------------SNDLFTTEMRYGEEPEEEPKVKTQWPRSADEPG 301
Query: 347 FPAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFCVSSSYSTQCSGPLREQRLCNNSAVC 406
QTGDPAAEEWSPWSVCS TCG+G Q RTR CVSS Y T CSGPLRE R CNNSA C
Sbjct: 302 LYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSATC 361
Query: 407 PVHGAWDEWSPWSLCSSTCGRGFRDRTRTCRPPQFGGNPCEGPEKQTKFCNIALCPGRAV 466
PVHG W+EW WSLCS +CGRG R R RTC PPQ GG CEGPE QTK C++A CP V
Sbjct: 362 PVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMAACP---V 418
Query: 467 DGNWNEWSSWSACSASCSQGRQQRTRECNGPSYGGAECQGHWVETRDCFLQQCPV-DGKW 525
+G W EW W CS SC+ G QQR+R+C+ A C G +TR+C +CP D KW
Sbjct: 419 EGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSKW 478
Query: 526 QAWASWGSCSVTCGAGSQRRERVCSGPFFGGAACQGPQDEYRQCGTQRCPEPHEICDEDN 585
W +W CS TC G QRR R+C G C+G +E + C +RCP HE+C ++
Sbjct: 479 GPWNAWSLCSKTCDTGWQRRFRMCQATGTQGYPCEGTGEEVKPCSEKRCPAFHEMCRDEY 538
Query: 586 FGAVIWKETPAGEVAAVRCPRNATGLILRRCELDEEGIAYWEPPTYIRCVSIDYRNIQMM 645
+ WK+ AGE+ +CP NA+G RRC L +G+AYW P++ RC+S +YR + +
Sbjct: 539 VMLMTWKKAAAGEIIYNKCPPNASGSASRRCLLSAQGVAYWGLPSFARCISHEYRYLYLS 598
Query: 646 TREHLAKAQRGLPGEGVSEVIQTLVEISQDGTSYSGDLLSTIDVLRNMTEIFRRAYYSPT 705
REHLAK QR L GEG+S+V+++L E+ T YSGDLL ++D+LRN+T+ F+RA Y P+
Sbjct: 599 LREHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDLLFSVDILRNVTDTFKRATYVPS 658
Query: 706 PGDVQNFVQILSNLLAEENRDKWEEAQLAGPNAKELFRLVEDFVDVIGFRMKDLRDAYQV 765
DVQ F Q++S ++ EN++KW++AQ P + L R+VEDF+ ++G +K + + V
Sbjct: 659 ADDVQRFFQVVSFMVDAENKEKWDDAQQVSPGSVHLLRVVEDFIHLVGDALKAFQSSLIV 718
Query: 766 TDNLVLSIHKLPASG-ATDISFPMKGWRATGDWAKVPEDRVTVSKSVFSTGL-------- 816
TDNLV+SI + P S ++DI+FPM+G R DW + EDR+ + K V S
Sbjct: 719 TDNLVISIQREPVSAVSSDITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSSPGKPATSG 778
Query: 817 ---------------------------TEADEASVFVVGTVLYRNLGSFLALQRNTTVLN 849
+ DE+S FV+G VLYR LG L R +
Sbjct: 779 AAGSPGRGRGPGTVPPGPGHSHQRLLPADPDESSYFVIGAVLYRTLGLILPPPRPPLAVT 838
Query: 850 SKVISVTVKPPPRSLRTPL-EIEFAHMYNGTTNQTCILWDETDVPSSSAPPQLGPWSWRG 908
S+V++VTV+PP + PL +E +++ NGTT+ C WD + +SS G W
Sbjct: 839 SRVMTVTVRPPTQPPAEPLITVELSYIINGTTDPHCASWDYSRADASS-----GDWDTEN 893
Query: 909 CRTVPLDALRTRCLCDRLSTFAILAQLSADANMEKATLPSVTLIVGCGVSSLTLLMLVII 968
C+T+ A TRC C LSTFA+LAQ D +E A PSV L++GC VS + LL L+ I
Sbjct: 894 CQTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGSPSVPLVIGCAVSCMALLTLLAI 953
Query: 969 YVSVWRYIRSERSVILINFCLSIISSNALILIGQTQTRNKVVCTLVAAFLHFFFLSSFCW 1028
Y + WR+I+SERS+IL+NFCLSI++SN LIL+GQ++ +K VCT+ AAFLHFFFLSSFCW
Sbjct: 954 YAAFWRFIKSERSIILLNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCW 1013
Query: 1029 VLTEAWQSYMAVTGHLRNRLIRKRFLCLGWGLPALVVAISVGFTKAKGYSTMNYCWLSLE 1088
VLTEAWQSY+AV G +R RL+RKRFLCLGWGLPALVVA+SVGFT+ KGY T +YCWLSLE
Sbjct: 1014 VLTEAWQSYLAVIGRMRTRLVRKRFLCLGWGLPALVVAVSVGFTRTKGYGTSSYCWLSLE 1073
Query: 1089 GGLLYAFVGPAAAVVLVNMVIGILVFNKLVSKDGITDKKLKERAG--------------- 1133
GGLLYAFVGPAA +VLVNM+IGI+VFNKL+++DGI+DK K+RAG
Sbjct: 1074 GGLLYAFVGPAAVIVLVNMLIGIIVFNKLMARDGISDKSKKQRAGSERCPWASLLLPCSA 1133
Query: 1134 ------------------ASLWSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSL 1175
ASLWSSCVVLPLLALTWMSAVLA+TDRRS LFQ LFAVF+S
Sbjct: 1134 CGAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSA 1193
Query: 1176 EGFVIVMVHCILRREVQDAVKCRVVDRQEEGNGDSGGSFQNGHAQLMTDFEKDVDLACRS 1235
+GFVI VHC LRREVQD VKC++ + + + DS S +NG Q+++DFEKDVDLAC++
Sbjct: 1194 QGFVITAVHCFLRREVQDVVKCQMGVCRADESEDSPDSCKNGQLQILSDFEKDVDLACQT 1253
Query: 1236 VLNKDIAACRTATITGTLKRPSLPEEEKLK--LAHAKGPPTNFNSLPANVSKLHLHGSPR 1293
VL K++ C +TITGTL R SL E+E+ K L +G +F+ LP N+ + + SP
Sbjct: 1254 VLFKEVNTCNPSTITGTLSRLSLDEDEEPKSCLVGPEG-SLSFSPLPGNI-LVPMAASPG 1311
Query: 1294 YPGGPLPDFPNHSLTLKRDKAPKSSFVGDGDIFKKLDSELSRAQEKALDTSYVILPTATA 1353
P P +A G+G + ++LD R E + Y++LP T
Sbjct: 1312 LGEPPPP-----------QEANPVYMCGEGGL-RQLDLTWLRPTEPGSEGDYMVLPRRTL 1359
Query: 1354 TLRP---------KPKEEPKYSIHIDQMPQTRLIHLSTAPEASLPARSPPSRQPPSGGPP 1404
+L+P P+ P+ + + + H P + L P+ G
Sbjct: 1360 SLQPGGGGGGGEDAPRARPEGT---PRRAAKTVAHTEGYP-SFLSVDHSGLGLGPAYGSL 1415
Query: 1405 EAPPAQPPPPPPPPPPPPQQPLPPPPNLEPAPPSLGDPGEPAAHPGPSTGPSTKNENVAT 1464
+ P PPPP P Q P +PGE + P T P +T
Sbjct: 1416 QNPYGMTFQPPPPTPSARQVP---------------EPGE-RSRTMPRTVPG------ST 1453
Query: 1465 LSVSSLERRKSRYAELDFEKIMHTRKRHQDMFQDLNRKL--------QHAAEKDKE-VLG 1515
+ + SLER+K RY++LDFEK+MHTRKRH +++ +LN+K Q A+++K +
Sbjct: 1454 MKMGSLERKKLRYSDLDFEKVMHTRKRHSELYHELNQKFHTFDRYRSQSTAKREKRWSVS 1513
Query: 1516 PDSKPEK-----QQTPNKRPWESLRKAHGT-PTWVKKELEPLQPSPLEL----RSVEWER 1565
E+ + +P +RP S + H + T+ L L P P E R+ WE
Sbjct: 1514 SGGAAERSVCTDKPSPGERPSLSQHRRHQSWSTFKSMTLGSLPPKPRERLTLHRAAAWE- 1572
Query: 1566 SGATIPLVGQDIIDLQTEV 1584
T P G D QTEV
Sbjct: 1573 --PTEPPDG----DFQTEV 1585
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 248 bits (633), Expect = 3e-65
Identities = 134/360 (37%), Positives = 169/360 (46%), Gaps = 57/360 (15%)
Query: 231 RGDVCLRDAVAGGPENCLTSLTQDRGGHG----ATGGWKLWSLWGECTRDCGGGLQTRTR 286
R +C + A G + C S + R G W WSLW ECTR CG G QTRTR
Sbjct: 4552 RSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDGSWSEWSLWEECTRSCGRGNQTRTR 4611
Query: 287 TCLPAPGVEGGG--CEGVLEEGRQCNREACGPAGRTSSRSQSLRSTDARRREELGDELQQ 344
TC P V+ GG CEG E CN C G S+
Sbjct: 4612 TC-NNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGAWSA---------------------- 4648
Query: 345 FGFPAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFCVSSSYS---TQCSGPLREQRLCN 401
W PW CS +CG+G QTR R C + + + C G + ++CN
Sbjct: 4649 ---------------WQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCN 4693
Query: 402 NSAVCPVHGAWDEWSPWSLCSSTCGRGFRDRTRTCRPP--QFGGNPCEGPEKQTKFCNIA 459
CP+HG W W+ WS CS +CG G R RTR C P Q+GG CEG + Q+ FCN
Sbjct: 4694 ERN-CPIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSD 4752
Query: 460 LCPGRAVDGNWNEWSSWSACSASCSQGRQQRTRECNGP--SYGGAECQGHWVETRDCFLQ 517
CP GNW+ WS W CS +C+ G+ +R R C+ P S GG C G + + C
Sbjct: 4753 PCP---THGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTD 4809
Query: 518 QCPVDGKWQAWASWGSCSVTCGAGSQRRERVCSG--PFFGGAACQGPQDEYRQCGTQRCP 575
CPVDG W +W SW CS +CG G + R+R+C P GG C G + +C Q CP
Sbjct: 4810 MCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACP 4869
Score = 212 bits (540), Expect = 2e-54
Identities = 99/226 (43%), Positives = 128/226 (56%), Gaps = 13/226 (5%)
Query: 359 EWSPWSVCSSTCGEGWQTRTRFC---VSSSYSTQCSGPLREQRLCNNSAVCPVHGAWDEW 415
+WS W CS TCG+G Q R+R C + ++ C G E R C N CPV G+W EW
Sbjct: 4534 QWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKP-CPVDGSWSEW 4592
Query: 416 SPWSLCSSTCGRGFRDRTRTCRPP--QFGGNPCEGPEKQTKFCNIALCPGRAVDGNWNEW 473
S W C+ +CGRG + RTRTC P Q GG PCEG + CNI CP V G W+ W
Sbjct: 4593 SLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEIIMCNIRPCP---VHGAWSAW 4649
Query: 474 SSWSACSASCSQGRQQRTRECNGP--SYGGAECQGHWVETRDCFLQQCPVDGKWQAWASW 531
W CS SC +G Q R R CN P ++GG+ C G + + C + CP+ GKW WASW
Sbjct: 4650 QPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCPIHGKWATWASW 4709
Query: 532 GSCSVTCGAGSQRRERVCSGPF--FGGAACQGPQDEYRQCGTQRCP 575
+CSV+CG G+++R R CS P +GG C+G + C + CP
Sbjct: 4710 SACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCP 4755
Score = 180 bits (457), Expect = 8e-45
Identities = 78/177 (44%), Positives = 107/177 (60%), Gaps = 9/177 (5%)
Query: 405 VCPVHGAWDEWSPWSLCSSTCGRGFRDRTRTCRP--PQFGGNPCEGPEKQTKFCNIALCP 462
+ VHG + +WS W CS TCG+G + R+R C P GG PC+G + + + C CP
Sbjct: 4525 IVQVHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCP 4584
Query: 463 GRAVDGNWNEWSSWSACSASCSQGRQQRTRECNGPS--YGGAECQGHWVETRDCFLQQCP 520
VDG+W+EWS W C+ SC +G Q RTR CN PS +GG C+G+ VE C ++ CP
Sbjct: 4585 ---VDGSWSEWSLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEIIMCNIRPCP 4641
Query: 521 VDGKWQAWASWGSCSVTCGAGSQRRERVCSG--PFFGGAACQGPQDEYRQCGTQRCP 575
V G W AW WG+CS +CG G+Q R R+C+ P FGG+ C G + + + C + CP
Sbjct: 4642 VHGAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4698
Score = 134 bits (337), Expect = 7e-31
Identities = 79/228 (34%), Positives = 99/228 (43%), Gaps = 27/228 (11%)
Query: 262 GGWKLWSLWGECTRDCGGGLQTRTRTCL-PAPGVEGGGCEGVLEEGRQCNREACGPAGRT 320
G W W WG C+ CG G QTR R C P P G C+G + + CN C G+
Sbjct: 4644 GAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCPIHGKW 4703
Query: 321 ------SSRSQSLRSTDARRREELGDELQQFGFPAPQTGD-----------PAAEEWSPW 363
S+ S S +R D + Q+G + D P WSPW
Sbjct: 4704 ATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTHGNWSPW 4763
Query: 364 S---VCSSTCGEGWQTRTRFCVS---SSYSTQCSGPLREQRLCNNSAVCPVHGAWDEWSP 417
S CS TC G R R C + S+ C GP + + CN +CPV G+W W
Sbjct: 4764 SGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTD-MCPVDGSWGSWHS 4822
Query: 418 WSLCSSTCGRGFRDRTRTCRPPQ--FGGNPCEGPEKQTKFCNIALCPG 463
WS CS++CG G + R R C P GG PC G Q CN+ CPG
Sbjct: 4823 WSQCSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPG 4870
>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
sapiens]
Length = 3014
Score = 228 bits (580), Expect = 5e-59
Identities = 222/887 (25%), Positives = 376/887 (42%), Gaps = 144/887 (16%)
Query: 403 SAVCP----VHGAWDEWSPWS-------LCSSTCGRGFRDRTRTC--RPPQFGGNPCE-G 448
S+ CP H AW+++S C C + C P G CE G
Sbjct: 1878 SSPCPPNSRCHDAWEDYSCVCDKGYLGINCVDACHLNPCENMGACVRSPGSPQGYVCECG 1937
Query: 449 PEKQTKFCNIAL---CPGRAVDGNWNEWSSWSACSASCSQGRQQRTRECNGPSYGGAECQ 505
P +C L CP G W C + S+G + NG +C+
Sbjct: 1938 PSHYGPYCENKLDLPCPR----GWWGN-PVCGPCHCAVSKGFDPDCNKTNGQ----CQCK 1988
Query: 506 GHWVETR--------DCFLQQCPVDGKWQAWASWGSCSVTCGAGSQRRERVCSGPFFGGA 557
++ + DCF GS S TC + + P G
Sbjct: 1989 ENYYKLLAQDTCLPCDCFPH--------------GSHSRTCDMATGQ---CACKPGVIGR 2031
Query: 558 ACQGPQDEYRQCGTQRCPEPHEICDEDNFGAVIWKETPAGEVAAVRCPRNATGLILRRCE 617
C + + + T C + C + + W +T G+ AAV CP+ + G +R C
Sbjct: 2032 QCNRCDNPFAEVTTLGCEVIYNGCPKAFEAGIWWPQTKFGQPAAVPCPKGSVGNAVRHCS 2091
Query: 618 LDEEGIAYWEPPTYIRCVSIDYRNIQMMTREHLAKAQRGLPGEGVSEVIQTLVEISQD-G 676
E+G W PP C +I + +++ M E L++ + + G ++++ L +Q G
Sbjct: 2092 -GEKG---WLPPELFNCTTISFVDLRAMN-EKLSRNETQVDGARALQLVRALRSATQHTG 2146
Query: 677 TSYSGDLLSTIDVLRNMT--EIFRRAYYSPTPGDVQNFVQIL---SNLLAEENRDKWEEA 731
T + D+ + +L ++ E +++ + D ++ S LLA R WE+
Sbjct: 2147 TLFGNDVRTAYQLLGHVLQHESWQQGFDLAATQDADFHEDVIHSGSALLAPATRAAWEQI 2206
Query: 732 QLAGPNAKELFRLVEDFVDVIG--FRMKDLRDAYQVTDNLVLSI---------------- 773
Q + +L R +E + + R LR VT N++L++
Sbjct: 2207 QRSEGGTAQLLRRLEGYFSNVARNVRRTYLRPFVIVTANMILAVDIFDKFNFTGARVPRF 2266
Query: 774 ----HKLPASGATDISFPMKGWRATGDWAKVPEDRV---------------------TVS 808
+ P + +SFP D+ + PE++ T
Sbjct: 2267 DTIHEEFPRELESSVSFP-------ADFFRPPEEKEGPLLRPAGRRTTPQTTRPGPGTER 2319
Query: 809 KSVFSTGLTEADEASVFVVGTVL-YRNLGSFLALQRNTT----------VLNSKVISVTV 857
++ S D+A F V V+ YR LG L + + ++N+ ++S V
Sbjct: 2320 EAPISRRRRHPDDAGQFAVALVIIYRTLGQLLPERYDPDRRSLRLPHRPIINTPMVSTLV 2379
Query: 858 ----KPPPRSLRTPLEIEFAHM-YNGTTNQTCILWDETDVPSSSAPPQLGPWSWRGCRTV 912
P PR L P+ +EFA + T C+ W+ S A G WS RGC +
Sbjct: 2380 YSEGAPLPRPLERPVLVEFALLEVEERTKPVCVFWNH-----SLAVGGTGGWSARGCELL 2434
Query: 913 PLDALRTRCLCDRLSTFAILAQLSADANMEKATLPSVTLIVGCGVS-SLTLLMLVIIYVS 971
+ C C ++FA+L +S N E L VT VS SL L++ + +S
Sbjct: 2435 SRNRTHVACQCSHTASFAVLMDISRRENGEVLPLKIVTY---AAVSLSLAALLVAFVLLS 2491
Query: 972 VWRYIRSERSVILINFCLSIISSNALILIGQTQTRNKVVCTLVAAFLHFFFLSSFCWVLT 1031
+ R +RS I + +++ S + +IG QT N +CT+VA LH+ ++S+F W L
Sbjct: 2492 LVRMLRSNLHSIHKHLAVALFLSQLVFVIGINQTENPFLCTVVAILLHYIYMSTFAWTLV 2551
Query: 1032 EAWQSYMAVTGHLRN--RLIRKRFLCLGWGLPALVVAISVGFTKAKGYSTMNYCWLSLEG 1089
E+ Y +T +RN + + +GWG+PA+V ++VG +GY ++CWLSL+
Sbjct: 2552 ESLHVYRMLT-EVRNIDTGPMRFYYVVGWGIPAIVTGLAVGL-DPQGYGNPDFCWLSLQD 2609
Query: 1090 GLLYAFVGPAAAVVLVNMVIGILVFNKLVSKDGITDKKLKERAGASLWSSCVVLPLLALT 1149
L+++F GP AV+++N V +L + VS K+ + L ++ ++L L++ T
Sbjct: 2610 TLIWSFAGPIGAVIIINTVTSVL--SAKVSCQRKHHYYGKKGIVSLLRTAFLLLLLISAT 2667
Query: 1150 WMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQDAVK 1196
W+ +LAV +R + F LFA+F L+G +++ HC+L +EV+ +K
Sbjct: 2668 WLLGLLAV-NRDALSFHYLFAIFSGLQGPFVLLFHCVLNQEVRKHLK 2713
>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
sapiens]
Length = 2923
Score = 207 bits (526), Expect = 8e-53
Identities = 239/974 (24%), Positives = 381/974 (39%), Gaps = 145/974 (14%)
Query: 280 GLQTRTRTCLPAPGVEGGGCEGVLEEGRQCNREACGPAGRTSSRSQSLRSTDARRREELG 339
GL T PG GG G C R S + + S D E +
Sbjct: 1736 GLHLSNITVGGIPGPAGGVARGF---------RGCLQGVRVSDTPEGVNSLDPSHGESIN 1786
Query: 340 DELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFCVSSSYSTQCSG-----PL 394
E Q P P +P +S C W + + C Y C+ P
Sbjct: 1787 VE-QGCSLPDPCDSNPCP--------ANSYCSNDWDSYSCSCDPGYYGDNCTNVCDLNPC 1837
Query: 395 REQRLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRDRTRTCRPPQFG--GNPCEGPEKQ 452
Q +C P HG E P L G TR +P G G+P GP
Sbjct: 1838 EHQSVCTRKPSAP-HGYTCECPPNYL-------GPYCETRIDQPCPRGWWGHPTCGP--- 1886
Query: 453 TKFCNIALCPGRAVDGNWNEWSSWSACSASCSQGRQQRTRECNGPSYGGAECQGHWVETR 512
CN + G D + N+ S C ++ R P+ +C +R
Sbjct: 1887 ---CNCDVSKG--FDPDCNKTSGECHC-------KENHYRPPGSPTCLLCDCYPTGSLSR 1934
Query: 513 DCFLQQCPVDGKWQAWASWGSCSVTCGAGSQRRERVCSGPFFGGAACQGPQDEYRQCGTQ 572
C P DG+ C G ++ +R C PF + T
Sbjct: 1935 VCD----PEDGQ---------CPCKPGVIGRQCDR-CDNPF-------------AEVTTN 1967
Query: 573 RCPEPHEICDEDNFGAVIWKETPAGEVAAVRCPRNATGLILRRCELDEEGIAYWEPPTYI 632
C ++ C + W T G AA CP+ + G +R C+ + G W PP
Sbjct: 1968 GCEVNYDSCPRAIEAGIWWPRTRFGLPAAAPCPKGSFGTAVRHCD-EHRG---WLPPNLF 2023
Query: 633 RCVSIDYRNIQMMTREHLAKAQRGLPGEGVSEVIQTLVEISQDGTSYSGDLLSTIDVLRN 692
C SI + ++ E L + + GL ++ L +Q Y G + L
Sbjct: 2024 NCTSITFSELKGFA-ERLQRNESGLDSGRSQQLALLLRNATQHTAGYFGSDVKVAYQLAT 2082
Query: 693 MT---EIFRRAYYSPTPGDV---QNFVQILSNLLAEENRDKWEEAQLAGPNAKELFRLVE 746
E +R + DV +N +++ S LL N+ WE Q L + E
Sbjct: 2083 RLLAHESTQRGFGLSATQDVHFTENLLRVGSALLDTANKRHWELIQQTEGGTAWLLQHYE 2142
Query: 747 DFVDVIGFRMKD--LRDAYQVTDNLVLSIHKLPASGATDISFPMKGWRATGDWAKVPEDR 804
+ + M+ L VT N+V+S+ +L P + G+ E
Sbjct: 2143 AYASALAQNMRHTYLSPFTIVTPNIVISVVRLDKGNFAGAKLP-RYEALRGEQPPDLETT 2201
Query: 805 VTVSKSVFS--------TGLTEADEASVF---------------VVGTVLYRNLGSFLAL 841
V + +SVF G EA E V ++YR L L
Sbjct: 2202 VILPESVFRETPPVVRPAGPGEAQEPEELARRQRRHPELSQGEAVASVIIYRTLAGLLPH 2261
Query: 842 QRNTT----------VLNSKVISVTVKPP----PRSLRTPLEIEFAHMYNGT-TNQTCIL 886
+ ++N+ V+S++V PR+L P+ ++F + T C+
Sbjct: 2262 NYDPDKRSLRVPKRPIINTPVVSISVHDDEELLPRALDKPVTVQFRLLETEERTKPICVF 2321
Query: 887 WDETDVPSSSAPPQLGPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADANMEKATL 946
W+ + + S + G WS RGC V + C C+ +++FA+L +S N E L
Sbjct: 2322 WNHSILVSGT-----GGWSARGCEVVFRNESHVSCQCNHMTSFAVLMDVSRRENGEILPL 2376
Query: 947 PSVTLIVGCGVSSLTLLMLVIIYVSVWRYIRSERSVILINFCLSIISSNALILIGQTQTR 1006
++T V GV+ L L+L ++++ R +RS + I N ++ + + L+G Q
Sbjct: 2377 KTLTY-VALGVT-LAALLLTFFFLTLLRILRSNQHGIRRNLTAALGLAQLVFLLGINQAD 2434
Query: 1007 NKVVCTLVAAFLHFFFLSSFCWVLTEAWQSYMAVTGHLR--NRLIRKRFLCLGWGLPALV 1064
CT++A LHF +L +F W L EA Y A+T +R N + + LGWG+PA +
Sbjct: 2435 LPFACTVIAILLHFLYLCTFSWALLEALHLYRALT-EVRDVNTGPMRFYYMLGWGVPAFI 2493
Query: 1065 VAISVGFTKAKGYSTMNYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNK--LVSKDG 1122
++VG +GY ++CWLS+ L+++F GP A V +++ + IL + G
Sbjct: 2494 TGLAVGL-DPEGYGNPDFCWLSIYDTLIWSFAGPVAFAVSMSVFLYILAARASCAAQRQG 2552
Query: 1123 ITDKKLKERAGASLWSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVM 1182
K+ + L S VL LL+ TW+ A+L+V + + LF LFA + ++G I +
Sbjct: 2553 FE----KKGPVSGLQPSFAVLLLLSATWLLALLSV-NSDTLLFHYLFATCNCIQGPFIFL 2607
Query: 1183 VHCILRREVQDAVK 1196
+ +L +EV+ A+K
Sbjct: 2608 SYVVLSKEVRKALK 2621
>gi|6912464 latrophilin 2 precursor [Homo sapiens]
Length = 1403
Score = 193 bits (490), Expect = 1e-48
Identities = 160/651 (24%), Positives = 285/651 (43%), Gaps = 67/651 (10%)
Query: 575 PEPHEICDEDNFGAVIWKETPAGEVAAVRCPRNATGLILRRCELDEEGIAYWEP--PTYI 632
P P C+ + + W +T G + CP+ G C + W P P
Sbjct: 463 PLPERFCEALDSKGIKWPQTQRGMMVERPCPKGTRGTASYLCMIST---GTWNPKGPDLS 519
Query: 633 RCVSIDYRNIQMMTREHLAKAQRGLPGEGVSEVIQTLVEISQDGTSYSGDLLSTIDVLRN 692
C S + AQ+ GE + + L + ++ G ++GD+ S++ ++
Sbjct: 520 NCTSHWVNQL----------AQKIRSGENAASLANELAKHTK-GPVFAGDVSSSVRLMEQ 568
Query: 693 MTEIFRRAYYSPTPGDVQN--------FVQILSNLLAEENRDKWEEAQLA--GPNAKELF 742
+ +I P + + V + NLL E + W+ + A L
Sbjct: 569 LVDILDAQLQELKPSEKDSAGRSYNKAIVDTVDNLLRPEALESWKHMNSSEQAHTATMLL 628
Query: 743 RLVEDFVDVIGFRMKDLRDAYQVTDNLVLSIHKLPASGAT-DISFPMKGWRATGDWAKVP 801
+E+ V+ + + T+N+VL + L G D FP+ G + G ++
Sbjct: 629 DTLEEGAFVLADNLLEPTRVSMPTENIVLEVAVLSTEGQIQDFKFPL-GIKGAGSSIQLS 687
Query: 802 EDRVTVSKSVFSTGLTEADEASVFVVGTVLYRNLGSFLALQ------------RNTTV-L 848
+ V K GL + VF++ YR+LG FL+ + RN+T+ +
Sbjct: 688 ANTV---KQNSRNGLAKL----VFII----YRSLGQFLSTENATIKLGADFIGRNSTIAV 736
Query: 849 NSKVISVTVKPPPRS--LRTPLEIEFAHMY-NGTTNQTCILWDETDVPSSSAPPQLGPWS 905
NS VISV++ L P+ H+ + N C W+ ++ +G WS
Sbjct: 737 NSHVISVSINKESSRVYLTDPVLFTLPHIDPDNYFNANCSFWNYSE------RTMMGYWS 790
Query: 906 WRGCRTVPLDALRTRCLCDRLSTFAILAQLSADANMEKATLPSVTLIVGCG-VSSLTLLM 964
+GC+ V + RT C C L+ FAIL A + +T+I G V SL L
Sbjct: 791 TQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDGVHELLLTVITWVGIVISLVCLA 850
Query: 965 LVIIYVSVWRYIRSERSVILINFCLSIISSNALILIGQTQTRNKVVCTLVAAFLHFFFLS 1024
+ I +R ++S+R+ I N C+++ + + LIG +T+ + C + A LHFFFL+
Sbjct: 851 ICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKTKYAIACPIFAGLLHFFFLA 910
Query: 1025 SFCWVLTEAWQSYMAVTGHLRNRLIRKRFLCL-GWGLPALVVAISVGFTKAKGYSTMNYC 1083
+F W+ E Q Y+ + + RK++ + G+ PA VV +S K Y T C
Sbjct: 911 AFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSAAI-DYKSYGTEKAC 969
Query: 1084 WLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNKLVSKDGI--TDKKLKERAGASLWSSCV 1141
WL ++ +++F+GP ++L+N++ ++ K+V D E + + +
Sbjct: 970 WLHVDNYFIWSFIGPVTFIILLNIIFLVITLCKMVKHSNTLKPDSSRLENIKSWVLGAFA 1029
Query: 1142 VLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQ 1192
+L LL LTW +L + + + + LF +F++ +G I + HC L+++V+
Sbjct: 1030 LLCLLGLTWSFGLLFINE-ETIVMAYLFTIFNAFQGVFIFIFHCALQKKVR 1079
>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
sapiens]
Length = 3312
Score = 192 bits (487), Expect = 3e-48
Identities = 176/694 (25%), Positives = 305/694 (43%), Gaps = 71/694 (10%)
Query: 556 GAACQGPQDEYRQCGTQRCPEPHEICDEDNFGAVIWKETPAGEVAAVRCPRNATGLILRR 615
G C + + C ++ C + V W +T G +A V CPR A G +R
Sbjct: 2104 GRQCNSCDSPFAEVTASGCRVLYDACPKSLRSGVWWPQTKFGVLATVPCPRGALGAAVRL 2163
Query: 616 CELDEEGIAYWEPPTYIRCVSIDYRNIQMMTREHLAKAQRGLPGEGVSEVIQTLVEISQD 675
C+ + +G W P C S +R + ++ + L + L ++ Q L E++
Sbjct: 2164 CD-EAQG---WLEPDLFNCTSPAFRELSLLL-DGLELNKTALDTMEAKKLAQRLREVTGH 2218
Query: 676 GTSY-SGDLLSTIDVLRNMT--EIFRRAYYSPTPGDV---QNFVQILSNLLAEENRDKW- 728
Y S D+ T +L ++ E ++ + D +N + S LLA E D W
Sbjct: 2219 TDHYFSQDVRVTARLLAHLLAFESHQQGFGLTATQDAHFNENLLWAGSALLAPETGDLWA 2278
Query: 729 ---EEAQLAGPNAKELFRLVEDFVDVIGFRMK--DLRDAYQVTDNLVLSIHKL--PASGA 781
+ A P + L R +E++ + M+ L VT N++LSI ++ P+S
Sbjct: 2279 ALGQRAPGGSPGSAGLVRHLEEYAATLARNMELTYLNPMGLVTPNIMLSIDRMEHPSSPR 2338
Query: 782 TDISFP------MKGWRATGDWAKV----------PEDRVTVSKSVFSTGLTEA------ 819
+P +G A V P + + S S+ ++ +
Sbjct: 2339 GARRYPRYHSNLFRGQDAWDPHTHVLLPSQSPRPSPSEVLPTSSSIENSTTSSVVPPPAP 2398
Query: 820 --DEASVFVVGTVLYRNLGSFLALQ----------RNTTVLNSKVISVTVKPPPRSLR-- 865
E + ++ ++YR LG L Q V+NS V+SV V LR
Sbjct: 2399 PEPEPGISIIILLVYRTLGGLLPAQFQAERRGARLPQNPVMNSPVVSVAVFHGRNFLRGI 2458
Query: 866 --TPLEIEFAHMYNGTTNQT-CILWDETDVPSSSAPPQLGPWSWRGCRTVPLDALRTRCL 922
+P+ +EF + ++ C+ WD + Q G W+ R C V + RC
Sbjct: 2459 LESPISLEFRLLQTANRSKAICVQWDPPGLAE-----QHGVWTARDCELVHRNGSHARCR 2513
Query: 923 CDRLSTFAILAQLSADANME-KATLPSVTLIVGCGVSSLTLLMLVIIYVSVWRYIRSERS 981
C R TF +L S +E L +V V VS L++ I +S+ R ++S
Sbjct: 2514 CSRTGTFGVLMDASPRERLEGDLELLAVFTHVVVAVSVAALVLTAAILLSL-RSLKSNVR 2572
Query: 982 VILINFCLSIISSNALILIGQTQTRNKVVCTLVAAFLHFFFLSSFCWVLTEAWQSY-MAV 1040
I N ++ + L L+G +T N++VCT VA LH+FFLS+F W+ + Y M V
Sbjct: 2573 GIHANVAAALGVAELLFLLGIHRTHNQLVCTAVAILLHYFFLSTFAWLFVQGLHLYRMQV 2632
Query: 1041 TGHLRNRLIRKRFLCLGWGLPALVVAISVGFTKAKGYSTMNYCWLSLEGGLLYAFVGPAA 1100
+R + + LGWG+PA+++ ++VG +GY ++CW+S+ L+++F GP
Sbjct: 2633 EPRNVDRGAMRFYHALGWGVPAVLLGLAVGL-DPEGYGNPDFCWISVHEPLIWSFAGPVV 2691
Query: 1101 AVVLVNMVIGILVFNKLVSKDGITDKKLKERAGASLWSSCVVLPLLALTWMSAVLAVTDR 1160
V+++N + +L S ++ K+ + +L SS ++L L++ +W+ +LAV
Sbjct: 2692 LVIVMNGTMFLLAARTSCSTG---QREAKKTSALTLRSSFLLLLLVSASWLFGLLAVNHS 2748
Query: 1161 RSALFQILFAVFDSLEGFVIVMVHCILRREVQDA 1194
A F L A L+G ++++ C+L + + A
Sbjct: 2749 ILA-FHYLHAGLCGLQGLAVLLLFCVLNADARAA 2781
>gi|163792198 latrophilin 3 precursor [Homo sapiens]
Length = 1469
Score = 187 bits (476), Expect = 5e-47
Identities = 166/677 (24%), Positives = 291/677 (42%), Gaps = 88/677 (12%)
Query: 571 TQRCPEPHEICDEDNFGAVIWKETPAGEVAAVRCPRNATGLILRRCELDEEGIAYWEPPT 630
+ + P E C+ ++W +T G++A CP G+ C L +GI W+P
Sbjct: 488 SSQIPALEESCEAVEAREIMWFKTRQGQIAKQPCPAGTIGVSTYLC-LAPDGI--WDPQ- 543
Query: 631 YIRCVSIDYRNIQMMTREHLAKAQRGLPGEGVSEVIQTLVEISQDGTSYSGDLLSTIDVL 690
D N H+ + + GE + + + L E +++ + +GD+ ++ +
Sbjct: 544 -----GPDLSNCSSPWVNHITQKLKS--GETAANIARELAEQTRNHLN-AGDITYSVRAM 595
Query: 691 RNMTEIFRRAYYSPTPGD---------------------VQNFVQILSNLLAEENRDKWE 729
+ + + TPG VQ V+ ++NLL + + W
Sbjct: 596 DQLVGLLDVQLRNLTPGGKDSAARSLNKLQKRERSCRAYVQAMVETVNNLLQPQALNAWR 655
Query: 730 EAQLAGP--NAKELFRLVEDFVDVIGFRMKDLRDAYQVTDNLVLSIHKLPASG-ATDISF 786
+ + A L VE+ V+ + + TDN+ L + +L G D+ F
Sbjct: 656 DLTTSDQLRAATMLLHTVEESAFVLADNLLKTDIVRENTDNIKLEVARLSTEGNLEDLKF 715
Query: 787 PMKGWRATGDWAKVPEDRVTVSKSVFSTGLTEADEASVFVVGTVLYRNLGSFLALQR--- 843
P + T+ S + L + V VLY NLG +L+ +
Sbjct: 716 PENMGHGS-----------TIQLS--ANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASM 762
Query: 844 ----------NTTVLNSKVISVTVKPPPRS---LRTPLEIEFAHMYNGTTN--QTCILWD 888
++ ++NS VI+ + + L P+ H+ N C W
Sbjct: 763 KLGTEALSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFW- 821
Query: 889 ETDVPSSSAPPQLGPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADANMEKATLPS 948
S S G WS +GCR + + T C C+ L+ FA+L + +
Sbjct: 822 -----SYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLL 876
Query: 949 VTLIVGCGVS-SLTLLMLVIIYVSVWRYIRSERSVILINFCLSIISSNALILIGQTQTRN 1007
+ +I G+ SL L++ I +R ++S+R+ I N C+S+ + L LIG +T
Sbjct: 877 LDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQ 936
Query: 1008 KVVCTLVAAFLHFFFLSSFCWVLTEAWQSY-MAVTGHLRNRLIRKRFLCLGWGLPALVVA 1066
+ C + AA LHFFFL++F W+ E Q Y M V RK F +G+G+PAL+VA
Sbjct: 937 PIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALIVA 996
Query: 1067 ISVGFTKAKGYSTMNYCWLSLEGGLLYAFVGPAAAVVLVNMV-IGILVFNK------LVS 1119
+S + Y T CWL L+ +++F+GPA ++++N++ +GI ++ L
Sbjct: 997 VSAA-VDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKP 1055
Query: 1120 KDGITDKKLKE--RAGASLW--SSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSL 1175
+ G D E R W + +L LL LTW ++ + + + + LF +F+SL
Sbjct: 1056 ESGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTWAFGLMYINE-STVIMAYLFTIFNSL 1114
Query: 1176 EGFVIVMVHCILRREVQ 1192
+G I + HC+L+++V+
Sbjct: 1115 QGMFIFIFHCVLQKKVR 1131
>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
Length = 1474
Score = 179 bits (453), Expect = 2e-44
Identities = 154/671 (22%), Positives = 282/671 (42%), Gaps = 85/671 (12%)
Query: 577 PHEICDEDNFGAVIWKETPAGEVAAVRCPRNATGLILRRCELDEEGIAYWEP--PTYIRC 634
P C+ V W T G + CP+ G+ +C + W P P C
Sbjct: 476 PELFCEPREVRRVQWPATQQGMLVERPCPKGTRGIASFQCL---PALGLWNPRGPDLSNC 532
Query: 635 VSIDYRNIQMMTREHLAKAQRGLPGEGVSEVIQTLVEISQDGTSYSGDLLSTIDVLRNMT 694
S + AQ+ GE + + L ++ G+ Y+GD+ S++ ++ +
Sbjct: 533 TSPWVNQV----------AQKIKSGENAANIASELARHTR-GSIYAGDVSSSVKLMEQLL 581
Query: 695 EIFRRAYYSPTPGD---------------------VQNFVQILSNLLAEENRDKWEEAQL 733
+I + P + ++ V+ + NLL E + W++
Sbjct: 582 DILDAQLQALRPIERESAGKNYNKMHKRERTCKDYIKAVVETVDNLLRPEALESWKDMNA 641
Query: 734 AGP--NAKELFRLVEDFVDVIGFRMKDLRDAYQVTDNLVLSIHKLPASGAT-DISFPMKG 790
A L ++E+ ++ +++ +N+VL + L G ++ FP +
Sbjct: 642 TEQVHTATMLLDVLEEGAFLLADNVREPARFLAAKENVVLEVTVLNTEGQVQELVFPQEE 701
Query: 791 WRATGDWAKVPEDRVTVSKSVFSTGLTEADEASVFVVGTVLYRNLGSFLALQRNTT---- 846
+ S + + + + V V +LY NLG FL+ + T
Sbjct: 702 YPRKN------------SIQLSAKTIKQNSRNGVVKVVFILYNNLGLFLSTENATVKLAG 749
Query: 847 ------------VLNSKVISVTVKPPPRS--LRTPLEIEFAHMYNGTT-NQTCILWDETD 891
V+NS+VI+ ++ L P+ AH+ + N C W+ ++
Sbjct: 750 EAGPGGPGGASLVVNSQVIAASINKESSRVFLMDPVIFTVAHLEDKNHFNANCSFWNYSE 809
Query: 892 VPSSSAPPQLGPWSWRGCRTVPLDALRTRCLCDRLSTFAIL-AQLSADANMEKATLPSVT 950
LG WS +GCR V + T C C L+ FA+L A L SV
Sbjct: 810 ------RSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHREIYQGRINELLLSVI 863
Query: 951 LIVGCGVSSLTLLMLVIIYVSVWRYIRSERSVILINFCLSIISSNALILIGQTQTRNKVV 1010
VG V SL L + I R ++++R+ I N C+++ + L L+G +T+ ++
Sbjct: 864 TWVGI-VISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDKTQYEIA 922
Query: 1011 CTLVAAFLHFFFLSSFCWVLTEAWQSYMAVTGHLRNRLIRKRFLCL-GWGLPALVVAISV 1069
C + A LH+FFL++F W+ E Y+ + + R ++ L G+ PALVV I+
Sbjct: 923 CPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLGGYCFPALVVGIAA 982
Query: 1070 GFTKAKGYSTMNYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNKLVSKDGITDKKLK 1129
+ Y T CWL ++ +++F+GP + V++VN+V ++ +K++ +
Sbjct: 983 AI-DYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSS 1041
Query: 1130 ERAGASLWS--SCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCIL 1187
W+ + +L LL LTW +L + ++ S + LF F++ +G I + HC L
Sbjct: 1042 RLDNIKSWALGAIALLFLLGLTWAFGLLFI-NKESVVMAYLFTTFNAFQGVFIFVFHCAL 1100
Query: 1188 RREV-QDAVKC 1197
+++V ++ KC
Sbjct: 1101 QKKVHKEYSKC 1111
Score = 36.2 bits (82), Expect = 0.26
Identities = 29/97 (29%), Positives = 37/97 (38%), Gaps = 2/97 (2%)
Query: 1357 PKPKEEPKYSIHIDQMPQTRLIHLSTAPEASLPARSPPSRQPPSGGPPEAPPAQPPPPPP 1416
P P P S + R L++ AS A +P R P + P A P PP
Sbjct: 399 PDPSAGPATSPPLSTTTTARPTPLTST--ASPAATTPLRRAPLTTHPVGAINQLGPDLPP 456
Query: 1417 PPPPPPQQPLPPPPNLEPAPPSLGDPGEPAAHPGPST 1453
P P PP PNL +P +P E P+T
Sbjct: 457 ATAPVPSTRRPPAPNLHVSPELFCEPREVRRVQWPAT 493
Score = 35.8 bits (81), Expect = 0.34
Identities = 23/68 (33%), Positives = 23/68 (33%), Gaps = 14/68 (20%)
Query: 1387 SLPARSPPSRQP--------------PSGGPPEAPPAQPPPPPPPPPPPPQQPLPPPPNL 1432
S P SPP R P P A PPPPP PP PP PP L
Sbjct: 1372 SRPLSSPPGRDSLYASGANLRDSPSYPDSSPEGPSEALPPPPPAPPGPPEIYYTSRPPAL 1431
Query: 1433 EPAPPSLG 1440
P G
Sbjct: 1432 VARNPLQG 1439
>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
Length = 1469
Score = 179 bits (453), Expect = 2e-44
Identities = 154/671 (22%), Positives = 282/671 (42%), Gaps = 85/671 (12%)
Query: 577 PHEICDEDNFGAVIWKETPAGEVAAVRCPRNATGLILRRCELDEEGIAYWEP--PTYIRC 634
P C+ V W T G + CP+ G+ +C + W P P C
Sbjct: 471 PELFCEPREVRRVQWPATQQGMLVERPCPKGTRGIASFQCL---PALGLWNPRGPDLSNC 527
Query: 635 VSIDYRNIQMMTREHLAKAQRGLPGEGVSEVIQTLVEISQDGTSYSGDLLSTIDVLRNMT 694
S + AQ+ GE + + L ++ G+ Y+GD+ S++ ++ +
Sbjct: 528 TSPWVNQV----------AQKIKSGENAANIASELARHTR-GSIYAGDVSSSVKLMEQLL 576
Query: 695 EIFRRAYYSPTPGD---------------------VQNFVQILSNLLAEENRDKWEEAQL 733
+I + P + ++ V+ + NLL E + W++
Sbjct: 577 DILDAQLQALRPIERESAGKNYNKMHKRERTCKDYIKAVVETVDNLLRPEALESWKDMNA 636
Query: 734 AGP--NAKELFRLVEDFVDVIGFRMKDLRDAYQVTDNLVLSIHKLPASGAT-DISFPMKG 790
A L ++E+ ++ +++ +N+VL + L G ++ FP +
Sbjct: 637 TEQVHTATMLLDVLEEGAFLLADNVREPARFLAAKENVVLEVTVLNTEGQVQELVFPQEE 696
Query: 791 WRATGDWAKVPEDRVTVSKSVFSTGLTEADEASVFVVGTVLYRNLGSFLALQRNTT---- 846
+ S + + + + V V +LY NLG FL+ + T
Sbjct: 697 YPRKN------------SIQLSAKTIKQNSRNGVVKVVFILYNNLGLFLSTENATVKLAG 744
Query: 847 ------------VLNSKVISVTVKPPPRS--LRTPLEIEFAHMYNGTT-NQTCILWDETD 891
V+NS+VI+ ++ L P+ AH+ + N C W+ ++
Sbjct: 745 EAGPGGPGGASLVVNSQVIAASINKESSRVFLMDPVIFTVAHLEDKNHFNANCSFWNYSE 804
Query: 892 VPSSSAPPQLGPWSWRGCRTVPLDALRTRCLCDRLSTFAIL-AQLSADANMEKATLPSVT 950
LG WS +GCR V + T C C L+ FA+L A L SV
Sbjct: 805 ------RSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHREIYQGRINELLLSVI 858
Query: 951 LIVGCGVSSLTLLMLVIIYVSVWRYIRSERSVILINFCLSIISSNALILIGQTQTRNKVV 1010
VG V SL L + I R ++++R+ I N C+++ + L L+G +T+ ++
Sbjct: 859 TWVGI-VISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDKTQYEIA 917
Query: 1011 CTLVAAFLHFFFLSSFCWVLTEAWQSYMAVTGHLRNRLIRKRFLCL-GWGLPALVVAISV 1069
C + A LH+FFL++F W+ E Y+ + + R ++ L G+ PALVV I+
Sbjct: 918 CPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLGGYCFPALVVGIAA 977
Query: 1070 GFTKAKGYSTMNYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNKLVSKDGITDKKLK 1129
+ Y T CWL ++ +++F+GP + V++VN+V ++ +K++ +
Sbjct: 978 AI-DYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSS 1036
Query: 1130 ERAGASLWS--SCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCIL 1187
W+ + +L LL LTW +L + ++ S + LF F++ +G I + HC L
Sbjct: 1037 RLDNIKSWALGAIALLFLLGLTWAFGLLFI-NKESVVMAYLFTTFNAFQGVFIFVFHCAL 1095
Query: 1188 RREV-QDAVKC 1197
+++V ++ KC
Sbjct: 1096 QKKVHKEYSKC 1106
Score = 36.2 bits (82), Expect = 0.26
Identities = 29/97 (29%), Positives = 37/97 (38%), Gaps = 2/97 (2%)
Query: 1357 PKPKEEPKYSIHIDQMPQTRLIHLSTAPEASLPARSPPSRQPPSGGPPEAPPAQPPPPPP 1416
P P P S + R L++ AS A +P R P + P A P PP
Sbjct: 394 PDPSAGPATSPPLSTTTTARPTPLTST--ASPAATTPLRRAPLTTHPVGAINQLGPDLPP 451
Query: 1417 PPPPPPQQPLPPPPNLEPAPPSLGDPGEPAAHPGPST 1453
P P PP PNL +P +P E P+T
Sbjct: 452 ATAPVPSTRRPPAPNLHVSPELFCEPREVRRVQWPAT 488
Score = 35.8 bits (81), Expect = 0.34
Identities = 23/68 (33%), Positives = 23/68 (33%), Gaps = 14/68 (20%)
Query: 1387 SLPARSPPSRQP--------------PSGGPPEAPPAQPPPPPPPPPPPPQQPLPPPPNL 1432
S P SPP R P P A PPPPP PP PP PP L
Sbjct: 1367 SRPLSSPPGRDSLYASGANLRDSPSYPDSSPEGPSEALPPPPPAPPGPPEIYYTSRPPAL 1426
Query: 1433 EPAPPSLG 1440
P G
Sbjct: 1427 VARNPLQG 1434
>gi|4505737 complement factor properdin precursor [Homo sapiens]
Length = 469
Score = 174 bits (442), Expect = 5e-43
Identities = 106/312 (33%), Positives = 133/312 (42%), Gaps = 63/312 (20%)
Query: 262 GGWKLWSLWGECTRDCGGGLQTRTRTCL-PAPGVEGGGCEGVLEEGRQCNREACGPAGRT 320
GGW W W C+ C G +TR R C PAP GG C G +E C+ + P
Sbjct: 137 GGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKC-GGHCPGQAQESEACDTQQVCPT--- 192
Query: 321 SSRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEG----WQT 376
A W PW+ CS++C G +T
Sbjct: 193 ---------------------------------HGAWATWGPWTPCSASCHGGPHEPKET 219
Query: 377 RTRFCVSSSYSTQ-----CSGPLREQRLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRD 431
R+R C + S + C G EQR C CPV G W W P S C TCG G
Sbjct: 220 RSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTM 279
Query: 432 RTRTCRPP--QFGGNPCEGPEKQTKFCNIAL-CPGRAVDGNWNEWSSWSAC------SAS 482
RTC P Q GG C G +T CN A+ CP VDG W+ W WS C S S
Sbjct: 280 EQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCP---VDGEWDSWGEWSPCIRRNMKSIS 336
Query: 483 CSQ--GRQQRTRECNGPSYGGAECQGHWVETRDCF-LQQCPVDGKWQAWASWGSCSVTCG 539
C + G+Q R R C G + G C G + R C+ +Q CP+ G W W++WG C CG
Sbjct: 337 CQEIPGQQSRGRTCRGRKFDGHRCAGQQQDIRHCYSIQHCPLKGSWSEWSTWGLCMPPCG 396
Query: 540 AGSQR-RERVCS 550
R R+R+C+
Sbjct: 397 PNPTRARQRLCT 408
Score = 172 bits (436), Expect = 2e-42
Identities = 109/337 (32%), Positives = 135/337 (40%), Gaps = 64/337 (18%)
Query: 264 WKLWSLWGECTRDCGGGLQTRTRTCLPAPG-VEGGGCEGVLEEGRQ-CNREACGPAGRTS 321
W LWS W C+ C G Q R R C+ G G G LE Q C + C P
Sbjct: 80 WSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQCCP----- 134
Query: 322 SRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFC 381
E+G W PW CS TC +G +TR R C
Sbjct: 135 ---------------EMG----------------GWSGWGPWEPCSVTCSKGTRTRRRAC 163
Query: 382 --VSSSYSTQCSGPLREQRLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRD----RTRT 435
+ C G +E C+ VCP HGAW W PW+ CS++C G + R+R
Sbjct: 164 NHPAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRK 223
Query: 436 CRPPQFG----GNPCEGPEKQTKFC-NIALCPGRAVDGNWNEWSSWSACSASCSQGRQQR 490
C P+ G PC G + + C + CP V G W W S C +C G+
Sbjct: 224 CSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCP---VAGGWGPWGPVSPCPVTCGLGQTME 280
Query: 491 TRECNG--PSYGGAECQGHWVETRDC-FLQQCPVDGKWQAWASWGSC------SVTCG-- 539
R CN P +GG C G T C CPVDG+W +W W C S++C
Sbjct: 281 QRTCNHPVPQHGGPFCAGDATRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEI 340
Query: 540 AGSQRRERVCSGPFFGGAACQGPQDEYRQC-GTQRCP 575
G Q R R C G F G C G Q + R C Q CP
Sbjct: 341 PGQQSRGRTCRGRKFDGHRCAGQQQDIRHCYSIQHCP 377
Score = 80.9 bits (198), Expect = 9e-15
Identities = 61/216 (28%), Positives = 81/216 (37%), Gaps = 39/216 (18%)
Query: 262 GGWKLWSLWGECTRDCGGG----LQTRTRTCL---PAPGVEGGGCEGVLEEGRQCN---- 310
G W W W C+ C GG +TR+R C P+ G C G+ E R+C
Sbjct: 194 GAWATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPP 253
Query: 311 ---REACGPAGRTSSRSQSLRSTDARRREELGDELQQFGFP---------------APQT 352
GP G S + + + Q G P P
Sbjct: 254 CPVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCP 313
Query: 353 GDPAAEEWSPWSVC------SSTCGE--GWQTRTRFCVSSSYST-QCSGPLREQRLCNNS 403
D + W WS C S +C E G Q+R R C + +C+G ++ R C +
Sbjct: 314 VDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRKFDGHRCAGQQQDIRHCYSI 373
Query: 404 AVCPVHGAWDEWSPWSLCSSTCG-RGFRDRTRTCRP 438
CP+ G+W EWS W LC CG R R R C P
Sbjct: 374 QHCPLKGSWSEWSTWGLCMPPCGPNPTRARQRLCTP 409
Score = 43.1 bits (100), Expect = 0.002
Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 11/102 (10%)
Query: 483 CSQGRQQRTRECNGPSYGGAECQGHWVETRDCF-------LQQCPVDGKWQAWASWGSCS 535
C ++ + +C G GG + + T + Q C +W W++W CS
Sbjct: 32 CFTQYEESSGKCKGLLGGGVSVEDCCLNTAFAYQKRSGGLCQPCR-SPRWSLWSTWAPCS 90
Query: 536 VTCGAGSQRRERVC---SGPFFGGAACQGPQDEYRQCGTQRC 574
VTC GSQ R R C +G G A + + + C Q+C
Sbjct: 91 VTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQC 132
>gi|223671861 complement factor properdin precursor [Homo sapiens]
Length = 469
Score = 174 bits (442), Expect = 5e-43
Identities = 106/312 (33%), Positives = 133/312 (42%), Gaps = 63/312 (20%)
Query: 262 GGWKLWSLWGECTRDCGGGLQTRTRTCL-PAPGVEGGGCEGVLEEGRQCNREACGPAGRT 320
GGW W W C+ C G +TR R C PAP GG C G +E C+ + P
Sbjct: 137 GGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKC-GGHCPGQAQESEACDTQQVCPT--- 192
Query: 321 SSRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEG----WQT 376
A W PW+ CS++C G +T
Sbjct: 193 ---------------------------------HGAWATWGPWTPCSASCHGGPHEPKET 219
Query: 377 RTRFCVSSSYSTQ-----CSGPLREQRLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRD 431
R+R C + S + C G EQR C CPV G W W P S C TCG G
Sbjct: 220 RSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTM 279
Query: 432 RTRTCRPP--QFGGNPCEGPEKQTKFCNIAL-CPGRAVDGNWNEWSSWSAC------SAS 482
RTC P Q GG C G +T CN A+ CP VDG W+ W WS C S S
Sbjct: 280 EQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCP---VDGEWDSWGEWSPCIRRNMKSIS 336
Query: 483 CSQ--GRQQRTRECNGPSYGGAECQGHWVETRDCF-LQQCPVDGKWQAWASWGSCSVTCG 539
C + G+Q R R C G + G C G + R C+ +Q CP+ G W W++WG C CG
Sbjct: 337 CQEIPGQQSRGRTCRGRKFDGHRCAGQQQDIRHCYSIQHCPLKGSWSEWSTWGLCMPPCG 396
Query: 540 AGSQR-RERVCS 550
R R+R+C+
Sbjct: 397 PNPTRARQRLCT 408
Score = 172 bits (436), Expect = 2e-42
Identities = 109/337 (32%), Positives = 135/337 (40%), Gaps = 64/337 (18%)
Query: 264 WKLWSLWGECTRDCGGGLQTRTRTCLPAPG-VEGGGCEGVLEEGRQ-CNREACGPAGRTS 321
W LWS W C+ C G Q R R C+ G G G LE Q C + C P
Sbjct: 80 WSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQCCP----- 134
Query: 322 SRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFC 381
E+G W PW CS TC +G +TR R C
Sbjct: 135 ---------------EMG----------------GWSGWGPWEPCSVTCSKGTRTRRRAC 163
Query: 382 --VSSSYSTQCSGPLREQRLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRD----RTRT 435
+ C G +E C+ VCP HGAW W PW+ CS++C G + R+R
Sbjct: 164 NHPAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRK 223
Query: 436 CRPPQFG----GNPCEGPEKQTKFC-NIALCPGRAVDGNWNEWSSWSACSASCSQGRQQR 490
C P+ G PC G + + C + CP V G W W S C +C G+
Sbjct: 224 CSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCP---VAGGWGPWGPVSPCPVTCGLGQTME 280
Query: 491 TRECNG--PSYGGAECQGHWVETRDC-FLQQCPVDGKWQAWASWGSC------SVTCG-- 539
R CN P +GG C G T C CPVDG+W +W W C S++C
Sbjct: 281 QRTCNHPVPQHGGPFCAGDATRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEI 340
Query: 540 AGSQRRERVCSGPFFGGAACQGPQDEYRQC-GTQRCP 575
G Q R R C G F G C G Q + R C Q CP
Sbjct: 341 PGQQSRGRTCRGRKFDGHRCAGQQQDIRHCYSIQHCP 377
Score = 80.9 bits (198), Expect = 9e-15
Identities = 61/216 (28%), Positives = 81/216 (37%), Gaps = 39/216 (18%)
Query: 262 GGWKLWSLWGECTRDCGGG----LQTRTRTCL---PAPGVEGGGCEGVLEEGRQCN---- 310
G W W W C+ C GG +TR+R C P+ G C G+ E R+C
Sbjct: 194 GAWATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPP 253
Query: 311 ---REACGPAGRTSSRSQSLRSTDARRREELGDELQQFGFP---------------APQT 352
GP G S + + + Q G P P
Sbjct: 254 CPVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCP 313
Query: 353 GDPAAEEWSPWSVC------SSTCGE--GWQTRTRFCVSSSYST-QCSGPLREQRLCNNS 403
D + W WS C S +C E G Q+R R C + +C+G ++ R C +
Sbjct: 314 VDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRKFDGHRCAGQQQDIRHCYSI 373
Query: 404 AVCPVHGAWDEWSPWSLCSSTCG-RGFRDRTRTCRP 438
CP+ G+W EWS W LC CG R R R C P
Sbjct: 374 QHCPLKGSWSEWSTWGLCMPPCGPNPTRARQRLCTP 409
Score = 43.1 bits (100), Expect = 0.002
Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 11/102 (10%)
Query: 483 CSQGRQQRTRECNGPSYGGAECQGHWVETRDCF-------LQQCPVDGKWQAWASWGSCS 535
C ++ + +C G GG + + T + Q C +W W++W CS
Sbjct: 32 CFTQYEESSGKCKGLLGGGVSVEDCCLNTAFAYQKRSGGLCQPCR-SPRWSLWSTWAPCS 90
Query: 536 VTCGAGSQRRERVC---SGPFFGGAACQGPQDEYRQCGTQRC 574
VTC GSQ R R C +G G A + + + C Q+C
Sbjct: 91 VTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQC 132
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 166 bits (421), Expect = 1e-40
Identities = 114/352 (32%), Positives = 149/352 (42%), Gaps = 64/352 (18%)
Query: 262 GGWKLWSLWGECTRDCGGGLQTRTRTCLPAPGVEGGG-CEGVLEEGRQCNREACGPAGRT 320
G W +W WG C+ CGGG Q+R R+C+ P GG C G +E C + C +G T
Sbjct: 2556 GAWAMWEAWGPCSVSCGGGHQSRQRSCVDPPPKNGGAPCPGASQERAPCGLQPC--SGGT 2613
Query: 321 SSRSQSLRSTDARRREELGDELQQFGF--PAPQTG-DPAAEEWSPWSVCSSTCGEGWQTR 377
R + +L Q G P P + DP A CS C EG +
Sbjct: 2614 DCE---------LGRVYVSADLCQKGLVPPCPPSCLDPKANR-----SCSGHCVEGCRCP 2659
Query: 378 TRFCVSSSYSTQCSGPLRE----------------------QRLCNNSAV------CPVH 409
+ + T+C PL E Q +C + CP+
Sbjct: 2660 PGLLL---HDTRCL-PLSECPCLVGEELKWPGVSFLLGNCSQCVCEKGELLCQPGGCPLP 2715
Query: 410 GAWDEWSPWSLCSSTCGRGFRDRTRTCR--PPQFGGNPCEGPEKQTKFCNIALCPGRAVD 467
W WS W+ C +CG G R R R+ P +GG PCEG ++ + C+ +C G V
Sbjct: 2716 CGWSAWSSWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCEGDRQELQGCH-TVC-GTEVF 2773
Query: 468 GNWNEWSSWSACSASC-----SQGRQQRTRECNGPSYGGAECQGHWVETRDCFLQQCPVD 522
G W W+SWS+CS SC G + R+R C PS G + C G + C CPV
Sbjct: 2774 G-WTPWTSWSSCSQSCLAPGGGPGWRSRSRLC--PSPGDSSCPGDATQEEPCSPPVCPVP 2830
Query: 523 GKWQAWASWGSCSVTCGAGSQRRERVCSGPFFGGAACQGPQDEYRQCGTQRC 574
W WA W +CS C G Q R R CS G C GP + R C TQ C
Sbjct: 2831 SIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQPC 2882
Score = 151 bits (381), Expect = 6e-36
Identities = 104/372 (27%), Positives = 138/372 (37%), Gaps = 89/372 (23%)
Query: 256 GGHGATGGWKLWSLWGECTRDCGGGLQTRTRTCLPAPGVEGGG-CEGVLEEGRQCNREAC 314
GG GW WS W C R CG G++ R R+ P GG CEG +E + C+ C
Sbjct: 2710 GGCPLPCGWSAWSSWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCEGDRQELQGCH-TVC 2768
Query: 315 GPAGRTSSRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSVCSSTC---- 370
G + FG+ W+ WS CS +C
Sbjct: 2769 G--------------------------TEVFGW----------TPWTSWSSCSQSCLAPG 2792
Query: 371 -GEGWQTRTRFCVSSSYSTQCSGPLREQRLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGF 429
G GW++R+R C S S+ C G ++ C + VCPV W W+PWS CS+ C G
Sbjct: 2793 GGPGWRSRSRLCPSPGDSS-CPGDATQEEPC-SPPVCPVPSIWGLWAPWSTCSAPCDGGI 2850
Query: 430 RDRTRTCRPPQFGGNPCEGPEKQTKFCNIALCPGRA------------------------ 465
+ R R+C G C GP QT+ CN C +
Sbjct: 2851 QTRGRSCSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQCHQEGGPCPRLCL 2910
Query: 466 VDGNWNEWSSWSACSASCSQGRQQRTRECNGPSYGGAECQGHWVET-------------- 511
G E + + A +C G C S + G +
Sbjct: 2911 TQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTC 2970
Query: 512 ----RDCFLQQCPVDGKWQAWASWGSCSVTCGAGSQRRERVCSGP--FFGGAACQGPQDE 565
C ++CPV W W W CS +C G +RR R + P FGGA CQGP E
Sbjct: 2971 VSGKMACTSERCPVACGWSPWTLWSLCSCSCNVGIRRRFRAGTAPPAAFGGAECQGPTME 3030
Query: 566 YRQCGTQRCPEP 577
C + CP P
Sbjct: 3031 AEFCSLRPCPGP 3042
Score = 147 bits (371), Expect = 8e-35
Identities = 125/414 (30%), Positives = 156/414 (37%), Gaps = 102/414 (24%)
Query: 262 GGWKLWSLWGECTRDCGGGLQTRTRTCL----PAPGVE---------------------- 295
G W W W +C+ CGGG Q R+R C P P +
Sbjct: 3646 GVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRE 3705
Query: 296 ---GGGC---------------EGVLEEGRQC------NREACG---PAGRTSSRSQSLR 328
G GC EG EEG C +R AC P T+ Q L
Sbjct: 3706 CQPGEGCPFSCAHVTQQVGCFSEGC-EEGCHCPEGTFQHRLACVQECPCVLTAWLLQELG 3764
Query: 329 STDARRREELG--DELQQFGFPAPQTG-------------------DPAAEEWSPWSVCS 367
+T + LG DEL G D WSPW CS
Sbjct: 3765 ATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFGPWSPWGPCS 3824
Query: 368 STCGE-GWQTRTRFCVSSSYSTQ---CSGPLREQRL-------CNNSAVCPVHG---AWD 413
+CG G +TR+R CV + + C GP ++ S V PV G W
Sbjct: 3825 RSCGGLGTRTRSRQCVLTMPTLSGQGCRGPRQDLECPSPDCPGAEGSTVEPVTGLPGGWG 3884
Query: 414 EWSPWSLCSSTCGR----GFRDRTRTCRPPQFGGNPC-EGPEKQTKFCNIALCPGR---A 465
WS WS CS +C +R RTR C G+P E P + +CPG A
Sbjct: 3885 PWSSWSPCSRSCTDPARPAWRSRTRLCLANCTMGDPLQERPCNLPSCTELPVCPGPGCGA 3944
Query: 466 VDGNWNEWSSWSACSASCSQGRQQRTRECNGPSYGGAECQG---HWVETRDCFLQQCPVD 522
+ +W W+ W CS SC G+Q+R R P GG C + E R C L+ CPV
Sbjct: 3945 GNCSWTSWAPWEPCSRSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVP 4004
Query: 523 GKWQAWASWGSCSVTCGAGSQRRERVCSGP--FFGGAACQGPQDEYRQCGTQRC 574
G W W+ W C +CG G R R CS P GGA C G + + R C C
Sbjct: 4005 GGWSRWSPWSWCDRSCGGGQSLRSRSCSSPPSKNGGAPCAGERHQARLCNPMPC 4058
Score = 132 bits (333), Expect = 2e-30
Identities = 132/487 (27%), Positives = 173/487 (35%), Gaps = 117/487 (24%)
Query: 196 CLAGSRSSHPCGIMQTPCAC-------LGGEAGGPAAGPLAPRGDVCLRDAVAGGPENCL 248
C G+ + + PC LG G P PL P ++ + NC
Sbjct: 3736 CPEGTFQHRLACVQECPCVLTAWLLQELGATIGDPGQ-PLGPGDELDSGQTLRTSCGNCS 3794
Query: 249 TSLTQDRGGHG-----------ATGGWKLWSLWGECTRDCGG-GLQTRTRTC-LPAPGVE 295
+ HG A GG+ WS WG C+R CGG G +TR+R C L P +
Sbjct: 3795 CA-------HGKLSCSLDDCFEADGGFGPWSPWGPCSRSCGGLGTRTRSRQCVLTMPTLS 3847
Query: 296 GGGCEGVLEEGRQCNREACGPAGRT--------------SSRSQSLRS-TDARRRE---- 336
G GC G ++ + + G G T SS S RS TD R
Sbjct: 3848 GQGCRGPRQDLECPSPDCPGAEGSTVEPVTGLPGGWGPWSSWSPCSRSCTDPARPAWRSR 3907
Query: 337 --------ELGDELQQFGFPAPQ-------------TGDPAAEEWSPWSVCSSTCGEGWQ 375
+GD LQ+ P G+ + W+PW CS +CG G Q
Sbjct: 3908 TRLCLANCTMGDPLQERPCNLPSCTELPVCPGPGCGAGNCSWTSWAPWEPCSRSCGVGQQ 3967
Query: 376 TRTR-FCVSSSYSTQCSGPL---REQRLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRD 431
R R + C L +E+R CN A CPV G W WSPWS C +CG G
Sbjct: 3968 RRLRAYRPPGPGGHWCPNILTAYQERRFCNLRA-CPVPGGWSRWSPWSWCDRSCGGGQSL 4026
Query: 432 RTRTCR--PPQFGGNPCEGPEKQTKFCNIALCPGRAVDGNWNEWSSWSACSASCS----- 484
R+R+C P + GG PC G Q + CN C G + + C CS
Sbjct: 4027 RSRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAG-MEVVTCANRCPRRCSDLQEG 4085
Query: 485 ---QGRQQRTRECNGPS-----------YGGAEC---QGH-WVE---------------- 510
Q Q + C P G +C QGH W
Sbjct: 4086 IVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAG 4145
Query: 511 TRDCFLQQC--PVDGKWQAWASWGSCSVTCGAGSQRRERVCSGPFFGGAACQGPQDEYRQ 568
C Q C P W W++W CS +CG Q+ S C+ Q + +
Sbjct: 4146 QLSCTAQPCPPPTHCAWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQSQSQP 4205
Query: 569 CGTQRCP 575
C CP
Sbjct: 4206 CPQPSCP 4212
Score = 127 bits (319), Expect = 9e-29
Identities = 98/337 (29%), Positives = 127/337 (37%), Gaps = 56/337 (16%)
Query: 262 GGWKLWSLWGECTRDCGGGLQTRTRTCLPAPGVEGGG-CEGVLEEGRQCNREACGPAGRT 320
GGW WS W C R CGGG R+R+C P GG C G + R CN C
Sbjct: 4005 GGWSRWSPWSWCDRSCGGGQSLRSRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPA 4064
Query: 321 SSRSQSLRSTDARRREEL-------GDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEG 373
+ + RR +L D++ Q G P+ P C T +G
Sbjct: 4065 GMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHCDCTDAQG 4124
Query: 374 WQTRTRFCVSSSYSTQCSG-PLREQRLCNNSAVC--PVHGAWDEWSPWSLCSSTCG-RGF 429
+ S + C+ + +L + C P H AW WS WS CS +CG RG
Sbjct: 4125 HS----WAPGSQHQDACNNCSCQAGQLSCTAQPCPPPTHCAWSHWSAWSPCSHSCGPRGQ 4180
Query: 430 RDRTRT---------CRPPQFGGNPCEGP--------------------EKQTKFCNI-- 458
+ R R+ CR Q PC P + + + C+
Sbjct: 4181 QSRFRSSTSGSWAPECREEQSQSQPCPQPSCPPLCLQGTRSRTLGDSWLQGECQRCSCTP 4240
Query: 459 --ALCPGR--AVDGNWNEWSSWSACSASCSQGRQQRTRECN--GPSYGGAECQGHWVETR 512
+C AV W WSSWS C SC G Q RTR C P + C G +TR
Sbjct: 4241 EGVICEDTECAVPEAWTLWSSWSDCPVSCGGGNQVRTRACRAAAPHHRSPPCLGPDTQTR 4300
Query: 513 DCFLQQCPVDGKWQAWASWGSCSVTCGAGSQRRERVC 549
Q CP + +W WG CS +CG G R C
Sbjct: 4301 Q---QPCPGLLEACSWGPWGPCSRSCGPGLASRSGSC 4334
Score = 125 bits (315), Expect = 2e-28
Identities = 114/408 (27%), Positives = 144/408 (35%), Gaps = 91/408 (22%)
Query: 257 GHGATGGWKLWSLWGECTRDCGGGLQTRTRTC-LPAPGVEGGGCEGVLEEGRQCNREACG 315
G GGW W W C+R CGGGL++RTR C P P G CEG +G C C
Sbjct: 3248 GCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCP 3307
Query: 316 PAGRTSSRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAE-EWSPWSVCSSTCGEGW 374
T+ G E G P P++ D W C G+
Sbjct: 3308 VTNCTAIE---------------GAEYSPCGPPCPRSCDDLVHCVWRCQPGCYCPPGQVL 3352
Query: 375 QTRTRFCVSSSYSTQCSGPLREQRL-----------CNNSAV-----------CPVHGAW 412
+ CV + + C L QR CN+ CPV G W
Sbjct: 3353 SSNGAICVQPGHCS-CLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGW 3411
Query: 413 DEWSPWSLCSSTCGRGFRDRTRTCR--PPQFGGNPC------EGPEKQTKFC-NIALCPG 463
WS W++CS C R R+R C PQ GG PC G + Q + C + A CP
Sbjct: 3412 CPWSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSYATCP- 3470
Query: 464 RAVDGNWNEWSSWSACSASCSQGRQQRTRECNGP--SYGGAECQGHWVETRDC--FLQQC 519
VDG W W WS C G+ R+R C+ P GG C G+ ++R C QC
Sbjct: 3471 --VDGAWGPWGPWSPCDMCL--GQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQC 3526
Query: 520 PVDGKWQAWASWG---------------------SCSVTCGA--GSQRRERVCSGPFFGG 556
G Q+ G C TCG G ++ +C P
Sbjct: 3527 TDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPP--AH 3584
Query: 557 AACQGPQDEYRQCGTQRCPEPHEICDEDNFGAVIWKETPAGEVAAVRC 604
CQ Q G PE F + W+ GEV C
Sbjct: 3585 CRCQ------YQPGAMGIPENQSRSAGSRFSS--WESLEPGEVVTGPC 3624
Score = 117 bits (293), Expect = 9e-26
Identities = 87/286 (30%), Positives = 106/286 (37%), Gaps = 66/286 (23%)
Query: 353 GDPAAEEWSPWSVCSSTCGEGWQTRTRFCVSSSYSTQ---------------CSGPLREQ 397
G+P W+PWS CS++CG R RFC S + CSGP E+
Sbjct: 3182 GEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAEE 3241
Query: 398 RLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRDRTRTC--RPPQFGGNPCEGPEKQTKF 455
C C G W W PWS CS +CG G R RTR C PPQ G+ CEGP Q +
Sbjct: 3242 EPCLLQG-CDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQGEV 3300
Query: 456 CNIALCPGRAVDGNWNEWSSWSACSASCSQGRQQRTR-------ECNGP-----SYGGAE 503
C CP + E + +S C C + C P S GA
Sbjct: 3301 CQALPCP--VTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRCQPGCYCPPGQVLSSNGAI 3358
Query: 504 C--------------QGHWVETR-----------------DCFLQQCPVDGKWQAWASWG 532
C Q H R +C CPV G W W+ W
Sbjct: 3359 CVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGWCPWSEWT 3418
Query: 533 SCSVTCGAGSQRRERVCS--GPFFGGAACQGPQDEY-RQCGTQRCP 575
CS C ++ R R C+ P GGA C G E Q + CP
Sbjct: 3419 MCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACP 3464
Score = 113 bits (283), Expect = 1e-24
Identities = 97/369 (26%), Positives = 124/369 (33%), Gaps = 104/369 (28%)
Query: 263 GWKLWSLWGECTRDCGGGLQTRTRTCLPAPGVEGGG-CEGVLEEGRQCNREAC-GPAGRT 320
GW W+LW C+ C G++ R R P GG C+G E C+ C GP G
Sbjct: 2987 GWSPWTLWSLCSCSCNVGIRRRFRAGTAPPAAFGGAECQGPTMEAEFCSLRPCPGPGG-- 3044
Query: 321 SSRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRF 380
EW PWS CS CG G++ RTR
Sbjct: 3045 --------------------------------------EWGPWSPCSVPCGGGYRNRTRG 3066
Query: 381 CVSS--SYST----QCSGPLREQRLCNNSAVCPVHGAWDEWS--PWSLCSSTCGRGFRDR 432
S +ST C+GP+ +CP W + + P S + RG
Sbjct: 3067 SSRSLMEFSTCGLQPCAGPV--------PGMCPRDKQWLDCAQGPASCAELSAPRGTNQT 3118
Query: 433 --------------TRTCRPPQ-----FGGN----------PCEGPEKQTKF-CNIALCP 462
C P Q G+ PCE + N + P
Sbjct: 3119 CHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWP 3178
Query: 463 GRAVDGNWNEWSSWSACSASCSQGRQQRTRECNG--------------PSYGGAECQGHW 508
+ W+ W+ WS CSASC R R R C P+ C G
Sbjct: 3179 CAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPE 3238
Query: 509 VETRDCFLQQCPVDGKWQAWASWGSCSVTCGAGSQRRERVCSGPFFGGAA--CQGPQDEY 566
E C LQ C G W W W CS +CG G + R R C P G C+GP+ +
Sbjct: 3239 AEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQG 3298
Query: 567 RQCGTQRCP 575
C CP
Sbjct: 3299 EVCQALPCP 3307
Score = 109 bits (272), Expect = 2e-23
Identities = 89/340 (26%), Positives = 127/340 (37%), Gaps = 71/340 (20%)
Query: 306 GRQCNREACGPAGRTSSRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSV 365
G +R C P+ + + L A RR +L + Q G D WS WS
Sbjct: 2456 GLPASRALCSPSQLSCGSGECL---SAERRCDLRPDCQD-GSDEDGCVDCVLAPWSVWSS 2511
Query: 366 CSSTCGEGWQTRTRFCVSSSYSTQCSGPLREQRLCNNSA---VCPVHGAWDEWSPWSLCS 422
CS +CG G + + + G R + S CPV GAW W W CS
Sbjct: 2512 CSRSCGLGLTFQRQELLRPPLP---GGSCPRDRFRSQSCFVQACPVAGAWAMWEAWGPCS 2568
Query: 423 STCGRGFRDRTRTC--RPPQFGGNPCEGPEKQTKFCNIALCPGRA--------VDGNWNE 472
+CG G + R R+C PP+ GG PC G ++ C + C G V + +
Sbjct: 2569 VSCGGGHQSRQRSCVDPPPKNGGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQ 2628
Query: 473 WSSWSACSASCSQGRQQRTRECNGPSYGGAECQGHWV--ETR------------------ 512
C SC + R+ C+G G C + +TR
Sbjct: 2629 KGLVPPCPPSCLDPKANRS--CSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWP 2686
Query: 513 ----------DCFLQQ---------CPVDGKWQAWASWGSCSVTCGAGSQRRERVCSGP- 552
C ++ CP+ W AW+SW C +CG+G + R R S P
Sbjct: 2687 GVSFLLGNCSQCVCEKGELLCQPGGCPLPCGWSAWSSWAPCDRSCGSGVRARFRSPSNPP 2746
Query: 553 -FFGGAACQGPQDEYRQCGTQRCPEPHEICDEDNFGAVIW 591
+GGA C+G + E + C H +C + FG W
Sbjct: 2747 AAWGGAPCEGDRQELQGC--------HTVCGTEVFGWTPW 2778
Score = 108 bits (269), Expect = 5e-23
Identities = 96/368 (26%), Positives = 124/368 (33%), Gaps = 100/368 (27%)
Query: 267 WSLWGECTRDCGGGLQTRTRTCLPAPGVEGGGCEGVLEEGRQCNREACGPAGRTSSRSQS 326
WS+W C+R CG GL T R L P + GG C + C +AC AG
Sbjct: 2506 WSVWSSCSRSCGLGL-TFQRQELLRPPLPGGSCPRDRFRSQSCFVQACPVAG-------- 2556
Query: 327 LRSTDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFCVS--- 383
A W W CS +CG G Q+R R CV
Sbjct: 2557 -----------------------------AWAMWEAWGPCSVSCGGGHQSRQRSCVDPPP 2587
Query: 384 SSYSTQCSGPLREQR-----------------------LCNNSAVCPVHGAWDEWSPWSL 420
+ C G +E+ LC V P + +
Sbjct: 2588 KNGGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCLDPKANRS 2647
Query: 421 CSSTCGRGFRD------RTRTCRP----PQFGGNPCEGP--------------EKQTKFC 456
CS C G R C P P G + P EK C
Sbjct: 2648 CSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNCSQCVCEKGELLC 2707
Query: 457 NIALCPGRAVDGNWNEWSSWSACSASCSQGRQQRTRECNGP--SYGGAECQGHWVETRDC 514
CP + W+ WSSW+ C SC G + R R + P ++GGA C+G E + C
Sbjct: 2708 QPGGCP---LPCGWSAWSSWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCEGDRQELQGC 2764
Query: 515 FLQQCPVDGKWQAWASWGSCSVTC-----GAGSQRRERVCSGPFFGGAACQGPQDEYRQC 569
W W SW SCS +C G G + R R+C P G ++C G + C
Sbjct: 2765 HTVCGTEVFGWTPWTSWSSCSQSCLAPGGGPGWRSRSRLCPSP--GDSSCPGDATQEEPC 2822
Query: 570 GTQRCPEP 577
CP P
Sbjct: 2823 SPPVCPVP 2830
Score = 106 bits (265), Expect = 2e-22
Identities = 123/487 (25%), Positives = 150/487 (30%), Gaps = 150/487 (30%)
Query: 181 PSRAACQMLCRWLDACLAGSRS----SHPCGIMQT---PCACLGG----------EAGGP 223
P C +WLD C G S S P G QT C C G P
Sbjct: 3085 PVPGMCPRDKQWLD-CAQGPASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCP 3143
Query: 224 AA--GPLAPRGDVCLRDAVAGGPENC--LTSLTQDRGGHGATGG---WKLWSLWGECTRD 276
A G L P G +R ENC ++ L + G W W+ W +C+
Sbjct: 3144 CAHEGHLYPPGSTVVRPC-----ENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSAS 3198
Query: 277 CGGGLQTRTRTC-------------LPAPGVEGGGCEGVLEEGRQCNREACGPAGRTSSR 323
CG R R C LP P C G E C + C AG
Sbjct: 3199 CGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPCLLQGCDRAGGWG-- 3256
Query: 324 SQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFC-- 381
W PWS CS +CG G ++RTR C
Sbjct: 3257 -----------------------------------PWGPWSHCSRSCGGGLRSRTRACDQ 3281
Query: 382 -VSSSYSTQCSGPLREQRLCNNSAVCPVHGAWD-EWSPWSLCSSTCGRGFRDRTR---TC 436
C GP + +C + CPV E + +S C C R D C
Sbjct: 3282 PPPQGLGDYCEGPRAQGEVC-QALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRC 3340
Query: 437 RPPQFGGNPCEGPEKQTKFCNIALC--PGRA----------------------------- 465
+P C P Q N A+C PG
Sbjct: 3341 QP------GCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCL 3394
Query: 466 ------------VDGNWNEWSSWSACSASCSQGRQQRTR--ECNGPSYGGAECQGHWVET 511
V G W WS W+ CS C + R+R C P +GGA C G E
Sbjct: 3395 EGRLNCTDLPCPVPGGWCPWSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEA 3454
Query: 512 RDCFLQQ-------CPVDGKWQAWASWGSCSVTCGAGSQRRERVCSGPFF--GGAACQGP 562
++ CPVDG W W W C + G R R CS P GG C G
Sbjct: 3455 GAQHQREACPSYATCPVDGAWGPWGPWSPCDMC--LGQSHRSRACSRPPTPEGGRPCPGN 3512
Query: 563 QDEYRQC 569
+ R C
Sbjct: 3513 HTQSRPC 3519
Score = 106 bits (264), Expect = 2e-22
Identities = 79/286 (27%), Positives = 105/286 (36%), Gaps = 74/286 (25%)
Query: 360 WSPWSVCSSTCGEGWQTRTRFCVSSSYS---TQCSGPLRE------QRLCNNSAVCPVHG 410
WS W++CS C ++R+R C + C+G E + C + A CPV G
Sbjct: 3414 WSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSYATCPVDG 3473
Query: 411 AWDEWSPWSLCSSTCGRGFRDRTRTCRPPQFGGNPCEGPEKQTKFC--NIALCP------ 462
AW W PWS C G+ R R + P GG PC G Q++ C N C
Sbjct: 3474 AWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQ 3533
Query: 463 -----GRAVDGNWNEWSSWSAC---------SASCSQGRQQRTRECNGPSYGGAECQ--- 505
G+ + + S S C + C G+ + C P++ + Q
Sbjct: 3534 SLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGA 3593
Query: 506 ---------------GHW-------VETRDC--------FLQ-----QCPVDGKWQAWAS 530
W V T C LQ CP G W +W
Sbjct: 3594 MGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWGP 3653
Query: 531 WGSCSVTCGAGSQRRERVCSGPFFGGAACQGPQDEYRQCGTQRCPE 576
W CSV+CG G Q R R C+ P C GP + R C TQ C E
Sbjct: 3654 WEDCSVSCGGGEQLRSRRCARP-----PCPGPARQSRTCSTQVCRE 3694
Score = 94.0 bits (232), Expect = 1e-18
Identities = 91/319 (28%), Positives = 112/319 (35%), Gaps = 59/319 (18%)
Query: 298 GCEGVLEEGRQCNREACGPAGRTSSRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAA 357
GC+G+L CGP S+ + + R+ A L D AP A+
Sbjct: 4518 GCQGLLPLSEWSEWSPCGPCLPPSALAPASRT--ALEEHWLRDPTGLSPTLAPLL---AS 4572
Query: 358 EEWSPWSVCSSTCGEGWQTRTRFCVSSSYSTQCSGPLREQRLCNNSAVCPVHGAWDEWSP 417
E+ G W C + PL +QRLC + CP W W P
Sbjct: 4573 EQHRHRLCLDPATGRPWTGAPHLCTA---------PLSQQRLCPDPGACPDSCQWSLWGP 4623
Query: 418 WSLCSSTCGRGFRDRTRT--------CRPP----QFGGNPCEGPEKQTKFCNIAL---CP 462
WS C C GFR R R CR P G PC E Q + CP
Sbjct: 4624 WSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCP 4683
Query: 463 GRAVDGNWNEWSSWSA-CSASCSQGRQQRTRE----------CNGPSYGGA--------- 502
D W+ C C Q ++ C PS +
Sbjct: 4684 HSCAD-LWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAV 4742
Query: 503 --ECQGHWV--ETRDCFLQQCPVDGKWQAWASWGSCSVTCGAGSQRRERVCSGPFFGGAA 558
+CQ E+ C Q+CPV G W AW+S CS CG G+ R R C G G A
Sbjct: 4743 QLDCQNCTCVNESLVCPHQECPVLGPWSAWSS---CSAPCGGGTMERHRTCEGG-PGVAP 4798
Query: 559 CQGPQDEYRQ-CGTQRCPE 576
CQ E RQ C Q CPE
Sbjct: 4799 CQAQDTEQRQECNLQPCPE 4817
Score = 83.2 bits (204), Expect = 2e-15
Identities = 108/430 (25%), Positives = 138/430 (32%), Gaps = 109/430 (25%)
Query: 213 CACLG---GEAGGPAAGPLAPRGDVCLRDAVAGGPENCLTSLTQDRGGHGATGGWKLWSL 269
C+CL G+ P A P G C G NC T L GGW WS
Sbjct: 3365 CSCLDLLTGQRHHPGARLARPDG--CNHCTCLEGRLNC-TDLPCP-----VPGGWCPWSE 3416
Query: 270 WGECTRDCGGGLQTRTRTCL-PAPGVEGGGCEGVL-EEGRQCNREACGPAGRTSSRSQSL 327
W C++ C G ++R+R C P P G C G E G Q REAC P+ T
Sbjct: 3417 WTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREAC-PSYATCPV---- 3471
Query: 328 RSTDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFCV---SS 384
D A W PWS C G+ R+R C +
Sbjct: 3472 --------------------------DGAWGPWGPWSPCDMCLGQSH--RSRACSRPPTP 3503
Query: 385 SYSTQCSGPLREQRLCN-NSAVC--------------PVHGAWDEWSPWSLCSS------ 423
C G + R C NS C P + + SP S+C
Sbjct: 3504 EGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQ 3563
Query: 424 -TCG--RGFRDRTRTCRPP-----QFGGNPCEGPEKQTKFCNI------ALCPGRAVDGN 469
TCG G + C PP Q+ PE Q++ +L PG V G
Sbjct: 3564 PTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGP 3623
Query: 470 ------------------------WNEWSSWSACSASCSQGRQQRTRECNGPSYGGAECQ 505
W+ W W CS SC G Q R+R C P G Q
Sbjct: 3624 CDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQ 3683
Query: 506 GHWVETRDCFLQQCPVDGKWQAWASWGSCSVTCGAGSQRRERVCSGPFFGGAACQGPQDE 565
T+ C CP ++ C +C +Q+ G G C +
Sbjct: 3684 SRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEG-CEEGCHCPEGTFQ 3742
Query: 566 YRQCGTQRCP 575
+R Q CP
Sbjct: 3743 HRLACVQECP 3752
Score = 80.9 bits (198), Expect = 9e-15
Identities = 109/421 (25%), Positives = 145/421 (34%), Gaps = 68/421 (16%)
Query: 188 MLCRWLDACLAGS-RSSHPCGIMQTPCACLGGEAGGPAAGPLAPRGDVCLRDAVAGGPEN 246
+LC D C G+ S+PC Q AC G PA L CL A E+
Sbjct: 1433 LLCDRQDDCGDGTDEPSYPCP--QGLLACADGRCLPPAL--LCDGHPDCLD---AADEES 1485
Query: 247 CLTSLTQDRGGHGATGGWKLWSLW-GECTRDCGGGLQTRTRTC----LPAPGVEG--GGC 299
CL +T G G L ++ + DC G C LP P G
Sbjct: 1486 CLGQVTCVPGEVSCVDGTCLGAIQLCDGVWDCPDGADEGPGHCPLPSLPTPPASTLPGPS 1545
Query: 300 EGVLEEGRQCNREA-----CGPAG-RTSSRSQSLRSTDARRREELGDELQQFGFPAPQTG 353
G L+ A CGP R S + R + E+ D + G G
Sbjct: 1546 PGSLDTASSPLASASPAPPCGPFEFRCGSGECTPRGWRCDQEEDCADGSDERG-----CG 1600
Query: 354 DPAAEEWSPWSVCSSTCGEGWQTRTRFCVSSSYSTQCSGPLREQRLCNNSAVCPVHGAWD 413
P A +P C G C P ++LC+ CP D
Sbjct: 1601 GPCAPHHAP-------CARG--------------PHCVSP---EQLCDGVRQCP--DGSD 1634
Query: 414 EWSPWSLCSSTCGRGFRDRTRTCRPPQFGGNP--------CEGPEKQTKFCNIALCPGRA 465
E C G +RT P N C+G + + P
Sbjct: 1635 EGP--DACGGLPALGGPNRTGLPCPEYTCPNGTCIGFQLVCDGQPDCGRPGQVGPSPEEQ 1692
Query: 466 VDGNWNEWSSWSACSASCSQGRQQRTRECNGPSYGGAE-CQGHWVETRDCFLQQCPVDGK 524
G W WS W CS +C Q R+R C+ + C G +++ CF CPVDG+
Sbjct: 1693 GCGAWGPWSPWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTAACPVDGE 1752
Query: 525 WQAWASWGSCSVTCGAGSQRRERVCSGPFFGGAACQG-PQDEYRQCGTQRCPE---PHEI 580
W W+ W CS C G+ R+R C P GG C P + T+ CP+ P+
Sbjct: 1753 WSTWSPWSVCSEPC-RGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNAT 1811
Query: 581 C 581
C
Sbjct: 1812 C 1812
Score = 73.2 bits (178), Expect = 2e-12
Identities = 118/490 (24%), Positives = 148/490 (30%), Gaps = 120/490 (24%)
Query: 192 WLDACLAGSRSSHPCGIMQTPCACLGGEAGGPAAGPLAPRGDVCLRDAVAGGPENCLTSL 251
W C S PC P CL G G +G+ C R + PE +
Sbjct: 4192 WAPECREEQSQSQPCPQPSCPPLCLQGTRSR-TLGDSWLQGE-CQRCSCT--PEGVICED 4247
Query: 252 TQDRGGHGATGGWKLWSLWGECTRDCGGGLQTRTRTC-LPAPGVEGGGCEGVLEEGRQ-- 308
T+ W LWS W +C CGGG Q RTR C AP C G + RQ
Sbjct: 4248 TEC----AVPEAWTLWSSWSDCPVSCGGGNQVRTRACRAAAPHHRSPPCLGPDTQTRQQP 4303
Query: 309 -------CNREACGPAGRT-----SSRSQSLRSTDARRREELGDELQQFGFPAPQTGDPA 356
C+ GP R+ +SRS S A+ +G P
Sbjct: 4304 CPGLLEACSWGPWGPCSRSCGPGLASRSGSCPCLMAKADPTCNSTFLHLDTQGCYSG-PC 4362
Query: 357 AEE-----WSPWSVCSSTCGEGWQTRTRF-----------------------CVSSSYST 388
EE WS W+ CS C Q R R C+ S+ S
Sbjct: 4363 PEECVWSSWSSWTRCS--CRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSE 4420
Query: 389 QCSGPLREQRLCNN--SAVCPVHGAWDEWSPWSLCSSTC--GRGFRDRTRTCRPP----- 439
P E C + + +C H + C C +G ++ C PP
Sbjct: 4421 DSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNC 4480
Query: 440 ------------------QFGGNPCEGPEKQTKFCNIALCPGRAVDGNWNEWSSWSAC-- 479
Q G CE + C C G W+EWS C
Sbjct: 4481 WHTSAAGAGMTLAPGDRLQLGCKECECRRGELH-CTSQGCQGLLPLSEWSEWSPCGPCLP 4539
Query: 480 -SASCSQGR-------------------------QQRTRECNGPSYG----GAE--CQGH 507
SA R Q R R C P+ G GA C
Sbjct: 4540 PSALAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPATGRPWTGAPHLCTAP 4599
Query: 508 WVETRDC-FLQQCPVDGKWQAWASWGSCSVTCGAGSQRRERVCSGPFFGGAACQGPQDEY 566
+ R C CP +W W W C V C G + R R GG C+ P +
Sbjct: 4600 LSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGG--CREPWAQ- 4656
Query: 567 RQCGTQRCPE 576
C CPE
Sbjct: 4657 ESCNGGPCPE 4666
Score = 68.9 bits (167), Expect = 4e-11
Identities = 106/419 (25%), Positives = 130/419 (31%), Gaps = 106/419 (25%)
Query: 197 LAGSRSSHPCGIMQTPCA----------------CLGGEAGGPAAGPLAPRGDVCLRDAV 240
LA + + PCG + C C G GP AP C R
Sbjct: 1556 LASASPAPPCGPFEFRCGSGECTPRGWRCDQEEDCADGSDERGCGGPCAPHHAPCARGPH 1615
Query: 241 AGGPENCLTSLTQ----------DRGGHGATGGWKLWSL--------WGEC--------- 273
PE + Q GG A GG L G C
Sbjct: 1616 CVSPEQLCDGVRQCPDGSDEGPDACGGLPALGGPNRTGLPCPEYTCPNGTCIGFQLVCDG 1675
Query: 274 TRDCGGGLQTRTRTCLPAPGVEGGGCEGVLEEGRQCNREACGPAGRTSSRSQSLRSTDAR 333
DCG R P+P +G G G C+R CGP G+ SR S
Sbjct: 1676 QPDCG-----RPGQVGPSPEEQGCGAWGPWSPWGPCSR-TCGPWGQGRSRRCSPLGLLVL 1729
Query: 334 RREELGDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFCVSSSYSTQCSGP 393
+ + Q F A D WSPWSVCS C G TR R C S +
Sbjct: 1730 QNCPGPEHQSQACFTAACPVDGEWSTWSPWSVCSEPC-RGTMTRQRQCHSPQNGGRTCAA 1788
Query: 394 L-------REQRLCNNSAVCPVHGAWDE--WSPWSLCSSTCGRGFRDRTRTCRPPQFGGN 444
L R+ + C CP E + P + C TC TC P G+
Sbjct: 1789 LPGGLHSTRQTKPCPQDG-CPNATCSGELMFQPCAPCPLTCDD--ISGQVTCPPDWPCGS 1845
Query: 445 P-CEGPEKQT-----------------------------KFCNIALC-----------PG 463
P C PE Q C + +C P
Sbjct: 1846 PGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLNPD 1905
Query: 464 RAVDGNWNEWSSWSACSASC-SQGRQQRTRECNG--PSYGGAECQGHWVETRDCFLQQC 519
AVD W+ WS W+ C C SQ Q R N PS G +C+G + R C + C
Sbjct: 1906 CAVDCGWSSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEPC 1964
Score = 47.8 bits (112), Expect = 9e-05
Identities = 70/273 (25%), Positives = 97/273 (35%), Gaps = 65/273 (23%)
Query: 267 WSLWGECTRDCGGGLQTRTRTCLPAPGVEGGGCEGVLEEGRQ-CNREACG--PAGRTSSR 323
WS W C+ CGGG R RTC PGV C+ E RQ CN + C P G+ S
Sbjct: 4769 WSAWSSCSAPCGGGTMERHRTCEGGPGV--APCQAQDTEQRQECNLQPCPECPPGQVLSA 4826
Query: 324 SQS--------LRSTDARRREEL-------GDELQQFGFPAPQTGDPAAEEWSPWSVCSS 368
+ L+ +E G +L G P T P + PW + +
Sbjct: 4827 CATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGL-TL 4885
Query: 369 TCGEGWQTRTRFCVSSSYSTQCSGPLREQRLCNNSAV--------CPVHGAWDEWSP--W 418
T E Q V + T+C +C+ A P W + +P
Sbjct: 4886 TLEEQAQELPPGTVLTRNCTRC--------VCHGGAFSCSLVDCQVPPGETWQQVAPGEL 4937
Query: 419 SLCSSTCGRGFRDRTRT-----------CRPPQF--GGNPCEGPEKQTKFCNIAL--CPG 463
LC TC +T++ C+P F PC PE + ++ PG
Sbjct: 4938 GLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCV-PEDHCECWHLGRPHLPG 4996
Query: 464 RAVDGNWNEWSSWSAC-SASCSQGRQQRTRECN 495
+EW AC S C GR T+ C+
Sbjct: 4997 -------SEWQ--EACESCLCLSGRPVCTQHCS 5020
Score = 41.6 bits (96), Expect = 0.006
Identities = 36/138 (26%), Positives = 49/138 (35%), Gaps = 4/138 (2%)
Query: 272 ECTRDCGGGLQTRTRTCLPAPGVEGGGCEG--VLEEGRQCNREACGPAGRTSSRSQSLRS 329
+C C L R + CL P G C ++++GR +C +++ S L
Sbjct: 4681 QCPHSCAD-LWDRVQ-CLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAP 4738
Query: 330 TDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFCVSSSYSTQ 389
A + + P P WS WS CS+ CG G R R C
Sbjct: 4739 AQAVQLDCQNCTCVNESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAP 4798
Query: 390 CSGPLREQRLCNNSAVCP 407
C EQR N CP
Sbjct: 4799 CQAQDTEQRQECNLQPCP 4816
>gi|147904700 semaphorin 5A [Homo sapiens]
Length = 1074
Score = 166 bits (420), Expect = 2e-40
Identities = 126/408 (30%), Positives = 160/408 (39%), Gaps = 66/408 (16%)
Query: 211 TPCACLGGEAGGPAAGPLAPRGDVCLRDAVAGGPENCLTSLTQDRGGHGATGGWKLWSLW 270
TPC G A G R C A G C + GGW W+ W
Sbjct: 550 TPCT----HTDGSAVGSCLCRTRSCDSPAPQCGGWQC-EGPGMEIANCSRNGGWTPWTSW 604
Query: 271 GECTRDCGGGLQTRTRTCL-PAPGVEGGGCEGVLEEGRQCNREAC----------GPAGR 319
C+ CG G Q R R+C P P G C G E R CN GP R
Sbjct: 605 SPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWGPWER 664
Query: 320 TSSRSQSLRSTDARRRE-ELGDELQQFGF--------PAPQTGDPAAEEWSPWS-VCSST 369
+++ ARRR E G + P P+ W+PW+ V S
Sbjct: 665 CTAQCGG--GIQARRRICENGPDCAGCNVEYQSCNTNPCPEL--KKTTPWTPWTPVNISD 720
Query: 370 CGEGWQTRTRFCVSSSYST----QCSGPLREQRLCNNSAVC------------------- 406
G ++ R R+ + + + E R C++
Sbjct: 721 NGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSA 780
Query: 407 -PVHGAWDEWSPWSLCSSTCGRGFRDRTRTCRPPQ--FGGNPCEGPEKQTKFCNIALCPG 463
V+GAW W+ WS CS C RG R+R R C P+ +GG PC GP + + CNI CP
Sbjct: 781 HTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCP- 839
Query: 464 RAVDGNWNEWSSWSACSASCSQGRQQRTRECNGPS--YGGAECQGHWVETRDCFLQQCPV 521
VDG W+ WS W+ CSA+C G RTR C+ P+ YGG C G E C Q CP
Sbjct: 840 --VDGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPE 897
Query: 522 DGKWQAWASWGSCSVTCGAGSQRRERVCSGPFFGGAACQGPQDEYRQC 569
W W+ W C + G Q R R C F G+ C G E R C
Sbjct: 898 S--WSEWSDWSECEAS---GVQVRARQCILLFPMGSQCSGNTTESRPC 940
Score = 146 bits (369), Expect = 1e-34
Identities = 103/345 (29%), Positives = 132/345 (38%), Gaps = 77/345 (22%)
Query: 262 GGWKLWSLWGECTRDCG---GGLQTRTRTC-LPAPGVEGGGCEGVLEEGRQCNREACGPA 317
G + +WS W CT G G RTR+C PAP G CEG E C+R
Sbjct: 541 GHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRN----G 596
Query: 318 GRTSSRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEGWQTR 377
G T W+ WS CS+TCG G+Q R
Sbjct: 597 GWT--------------------------------------PWTSWSPCSTTCGIGFQVR 618
Query: 378 TRFCVSSS---YSTQCSGPLREQRLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRDRTR 434
R C + + C G RE+R CN +CP H W W PW C++ CG G + R R
Sbjct: 619 QRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWGPWERCTAQCGGGIQARRR 678
Query: 435 TCRPPQFGGNPCEGPEKQTKFCNIALCPGRAVDGNWNEWSSWS--------------ACS 480
C G C G + + CN CP W W+ + C
Sbjct: 679 ICE----NGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISDNGGHYEQRFRYTCK 734
Query: 481 ASCSQ------GRQQ-RTRECNGPSYGGAECQGHWVE-TRDCFLQQCPVDGKWQAWASWG 532
A + GRQ+ R C+ G G + R V+G W AW SW
Sbjct: 735 ARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSAHTVNGAWSAWTSWS 794
Query: 533 SCSVTCGAGSQRRERVCSG--PFFGGAACQGPQDEYRQCGTQRCP 575
CS C G + R+RVC+ P +GG C GP EY++C CP
Sbjct: 795 QCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCP 839
Score = 121 bits (303), Expect = 6e-27
Identities = 73/212 (34%), Positives = 92/212 (43%), Gaps = 21/212 (9%)
Query: 373 GWQTRTRFCVSSSYSTQCSGPLREQRLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRD- 431
GW + C S S + + C + V G + WSPW+ C+ T G
Sbjct: 505 GWDVVMKKCTSLEESLSMTQWEQSISACPTRNLT-VDGHFGVWSPWTPCTHTDGSAVGSC 563
Query: 432 --RTRTC--RPPQFGGNPCEGPEKQTKFCNIALCPGRAVDGNWNEWSSWSACSASCSQGR 487
RTR+C PQ GG CEGP + C + +G W W+SWS CS +C G
Sbjct: 564 LCRTRSCDSPAPQCGGWQCEGPGMEIANC--------SRNGGWTPWTSWSPCSTTCGIGF 615
Query: 488 QQRTRECNGPS--YGGAECQGHWVETRDCFLQ-QCPVDGKWQAWASWGSCSVTCGAGSQR 544
Q R R C+ P+ +GG C G E R C CP W W W C+ CG G Q
Sbjct: 616 QVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWGPWERCTAQCGGGIQA 675
Query: 545 RERVCSGPFFGGAACQGPQDEYRQCGTQRCPE 576
R R+C G C G EY+ C T CPE
Sbjct: 676 RRRICE----NGPDCAGCNVEYQSCNTNPCPE 703
Score = 86.7 bits (213), Expect = 2e-16
Identities = 49/131 (37%), Positives = 63/131 (48%), Gaps = 14/131 (10%)
Query: 457 NIALCPGR--AVDGNWNEWSSWSACS---ASCSQGRQQRTRECNGPS--YGGAECQGHWV 509
+I+ CP R VDG++ WS W+ C+ S RTR C+ P+ GG +C+G +
Sbjct: 528 SISACPTRNLTVDGHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGM 587
Query: 510 ETRDCFLQQCPVDGKWQAWASWGSCSVTCGAGSQRRERVCSGPF--FGGAACQGPQDEYR 567
E + C +G W W SW CS TCG G Q R+R CS P GG C G E R
Sbjct: 588 E-----IANCSRNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREER 642
Query: 568 QCGTQRCPEPH 578
C PH
Sbjct: 643 YCNEHLLCPPH 653
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 165 bits (417), Expect = 4e-40
Identities = 108/321 (33%), Positives = 136/321 (42%), Gaps = 39/321 (12%)
Query: 264 WKLWSLWGECTRDCGGGLQTRTRTCLPAPGVEGGGCEGVLEEGRQCNREACGPAGRTSSR 323
W W W +C+ +CGGG+Q+R R C G C G E + CN E C R +
Sbjct: 725 WASWGSWSKCSSNCGGGMQSRRRAC-----ENGNSCLGCGVEFKTCNPEGCPEVRRNTPW 779
Query: 324 SQSL--RSTDARRREELGDELQQFGFPA-PQTGDPAAEEWSPWSVCSSTCGEGWQTRTRF 380
+ L T R+E Q+F F DP ++ +T TR
Sbjct: 780 TPWLPVNVTQGGARQE-----QRFRFTCRAPLADPHGLQFGRR-----------RTETRT 823
Query: 381 CVSSSYSTQCSGPLREQRLCNNSAVCP--VHGAWDEWSPWSLCSSTCGRGFRDRTRTCRP 438
C + S C + L + + P V G W W PWS CS C GFR R RTC
Sbjct: 824 CPADG-SGSCDTDALVEVLLRSGSTSPHTVSGGWAAWGPWSSCSRDCELGFRVRKRTCTN 882
Query: 439 PQ--FGGNPCEGPEKQTKFCNIALCPGRAVDGNWNEWSSWSACSASCSQGRQQRTRECNG 496
P+ GG PC G + + CN CP R G W+ W+SWS CSASC G QRTR C
Sbjct: 883 PEPRNGGLPCVGDAAEYQDCNPQACPVR---GAWSCWTSWSPCSASCGGGHYQRTRSCTS 939
Query: 497 PSYGGAE--CQGHWVETRDCFLQQCPVDGKWQAWASWGSCSVTCGAGSQRRERVCSGPFF 554
P+ E C G E C Q CP W W+ W C+ G+Q R R C
Sbjct: 940 PAPSPGEDICLGLHTEEALCATQACPEG--WSPWSEWSKCT---DDGAQSRSRHCEELLP 994
Query: 555 GGAACQGPQDEYRQCGTQRCP 575
G +AC G + R C P
Sbjct: 995 GSSACAGNSSQSRPCPYSEIP 1015
Score = 159 bits (401), Expect = 3e-38
Identities = 115/343 (33%), Positives = 133/343 (38%), Gaps = 69/343 (20%)
Query: 262 GGWKLWSLWGECTRDCGGGLQTRTRTCL-PAPGVEGGGCEGVLEEGRQCNREACGPAGRT 320
G W WS W C+ CG G Q R R+C PAP G C G E R CN
Sbjct: 665 GAWTPWSSWALCSTSCGIGFQVRQRSCSNPAPRHGGRICVGKSREERFCNENT------- 717
Query: 321 SSRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRF 380
P P A+ W WS CSS CG G Q+R R
Sbjct: 718 ---------------------------PCPVPIFWAS--WGSWSKCSSNCGGGMQSRRRA 748
Query: 381 CVSSSYSTQCSGPLREQRLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRDRTR---TCR 437
C + + C G E + CN CP W+PW + T G G R R TCR
Sbjct: 749 CENGN---SCLGCGVEFKTCNPEG-CPEVRRNTPWTPWLPVNVTQG-GARQEQRFRFTCR 803
Query: 438 PP-------QFGGNPCEG---PEKQTKFCN------IALCPG----RAVDGNWNEWSSWS 477
P QFG E P + C+ + L G V G W W WS
Sbjct: 804 APLADPHGLQFGRRRTETRTCPADGSGSCDTDALVEVLLRSGSTSPHTVSGGWAAWGPWS 863
Query: 478 ACSASCSQGRQQRTRECNGPS--YGGAECQGHWVETRDCFLQQCPVDGKWQAWASWGSCS 535
+CS C G + R R C P GG C G E +DC Q CPV G W W SW CS
Sbjct: 864 SCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAEYQDCNPQACPVRGAWSCWTSWSPCS 923
Query: 536 VTCGAGSQRRERVCS--GPFFGGAACQGPQDEYRQCGTQRCPE 576
+CG G +R R C+ P G C G E C TQ CPE
Sbjct: 924 ASCGGGHYQRTRSCTSPAPSPGEDICLGLHTEEALCATQACPE 966
Score = 120 bits (302), Expect = 8e-27
Identities = 84/245 (34%), Positives = 106/245 (43%), Gaps = 28/245 (11%)
Query: 352 TGDPAAEEWSPWSVCSSTCGEGWQT---RTRFCVS---SSYSTQCSGPLREQRLCNNSAV 405
T D WSPW C G+ + R R C S C GP + A
Sbjct: 607 TRDGGFGPWSPWQPCEHLDGDNSGSCLCRARSCDSPRPRCGGLDCLGP------AIHIAN 660
Query: 406 CPVHGAWDEWSPWSLCSSTCGRGFRDRTRTCR--PPQFGGNPCEGPEKQTKFCN-IALCP 462
C +GAW WS W+LCS++CG GF+ R R+C P+ GG C G ++ +FCN CP
Sbjct: 661 CSRNGAWTPWSSWALCSTSCGIGFQVRQRSCSNPAPRHGGRICVGKSREERFCNENTPCP 720
Query: 463 GRAVDGNWNEWSSWSACSASCSQGRQQRTRECNGPSYGGAECQGHWVETRDCFLQQCPVD 522
V W W SWS CS++C G Q R R C G C G VE + C + CP
Sbjct: 721 ---VPIFWASWGSWSKCSSNCGGGMQSRRRACE----NGNSCLGCGVEFKTCNPEGCPEV 773
Query: 523 GKWQAWASWGSCSVTCGAG--SQRRERVCSGPFFGGAACQGPQDEYRQCGTQRCP-EPHE 579
+ W W +VT G QR C P A G Q R+ T+ CP +
Sbjct: 774 RRNTPWTPWLPVNVTQGGARQEQRFRFTCRAPL---ADPHGLQFGRRRTETRTCPADGSG 830
Query: 580 ICDED 584
CD D
Sbjct: 831 SCDTD 835
Score = 98.2 bits (243), Expect = 6e-20
Identities = 65/209 (31%), Positives = 82/209 (39%), Gaps = 47/209 (22%)
Query: 258 HGATGGWKLWSLWGECTRDCGGGLQTRTRTCL-PAPGVEGGGCEGVLEEGRQCNREACGP 316
H +GGW W W C+RDC G + R RTC P P G C G E + CN +AC
Sbjct: 850 HTVSGGWAAWGPWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAEYQDCNPQACPV 909
Query: 317 AGRTSSRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEGWQT 376
G S W+ WS CS++CG G
Sbjct: 910 RGAWSC-------------------------------------WTSWSPCSASCGGGHYQ 932
Query: 377 RTRFCVSSSYSTQ---CSGPLREQRLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRDRT 433
RTR C S + S C G E+ LC A CP W WS WS C+ G + R+
Sbjct: 933 RTRSCTSPAPSPGEDICLGLHTEEALCATQA-CP--EGWSPWSEWSKCTDD---GAQSRS 986
Query: 434 RTCRPPQFGGNPCEGPEKQTKFCNIALCP 462
R C G + C G Q++ C + P
Sbjct: 987 RHCEELLPGSSACAGNSSQSRPCPYSEIP 1015
>gi|40317628 thrombospondin 2 precursor [Homo sapiens]
Length = 1172
Score = 160 bits (404), Expect = 1e-38
Identities = 76/193 (39%), Positives = 102/193 (52%), Gaps = 10/193 (5%)
Query: 390 CSGPLREQRLCNNSAVCPVHG--AWDEWSPWSLCSSTCGRGFRDRTRTCRPPQFGGNPCE 447
C+ P + C S + V G W W+ W+ CS TCG G + R R+C N C
Sbjct: 360 CASPSFVEGECCPSCLHSVDGEEGWSPWAEWTQCSVTCGSGTQQRGRSC---DVTSNTCL 416
Query: 448 GPEKQTKFCNIALCPGRA-VDGNWNEWSSWSACSASCSQGRQQRTRECNGP--SYGGAEC 504
GP QT+ C+++ C R DG W+ WS WS+CS +C G R R CN P GG C
Sbjct: 417 GPSIQTRACSLSKCDTRIRQDGGWSHWSPWSSCSVTCGVGNITRIRLCNSPVPQMGGKNC 476
Query: 505 QGHWVETRDCFLQQCPVDGKWQAWASWGSCSVTCGAGSQRRERVCSG--PFFGGAACQGP 562
+G ET+ C CP+DG+W W+ W +C+VTC G + R RVC+ P +GG AC G
Sbjct: 477 KGSGRETKACQGAPCPIDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGKACVGD 536
Query: 563 QDEYRQCGTQRCP 575
E + C + CP
Sbjct: 537 VQERQMCNKRSCP 549
Score = 154 bits (388), Expect = 9e-37
Identities = 89/231 (38%), Positives = 107/231 (46%), Gaps = 40/231 (17%)
Query: 353 GDPAAEEWSPWSVCSSTCGEGWQTRTRFCVSSSYSTQCSGPLREQRLCNNSAVCPVH--- 409
G+ W+ W+ CS TCG G Q R R C S C GP + R C+ S C
Sbjct: 380 GEEGWSPWAEWTQCSVTCGSGTQQRGRSC--DVTSNTCLGPSIQTRACSLSK-CDTRIRQ 436
Query: 410 -GAWDEWSPWSLCSSTCGRGFRDRTRTCRP--PQFGGNPCEGPEKQTKFCNIALCPGRAV 466
G W WSPWS CS TCG G R R C PQ GG C+G ++TK C A CP +
Sbjct: 437 DGGWSHWSPWSSCSVTCGVGNITRIRLCNSPVPQMGGKNCKGSGRETKACQGAPCP---I 493
Query: 467 DGNWNEWSSWSACSASCSQGRQQRTRECNG--PSYGGAECQGHWVETRDCFLQQCPVDGK 524
DG W+ WS WSAC+ +C+ G ++RTR CN P YGG C G E + C + CPVDG
Sbjct: 494 DGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCNKRSCPVDG- 552
Query: 525 WQAWASWGSCSVTCGAGSQRRERVCSGPFFGGAACQGPQDEYRQCGTQRCP 575
S P F GA C D CG+ CP
Sbjct: 553 -----------------------CLSNPCFPGAQCSSFPDGSWSCGS--CP 578
Score = 127 bits (320), Expect = 7e-29
Identities = 75/211 (35%), Positives = 91/211 (43%), Gaps = 46/211 (21%)
Query: 263 GWKLWSLWGECTRDCGGGLQTRTRTCLPAPGVEGGGCEGVLEEGRQCNREACGPAGRTSS 322
GW W+ W +C+ CG G Q R R+C V C G + R C+ C
Sbjct: 383 GWSPWAEWTQCSVTCGSGTQQRGRSC----DVTSNTCLGPSIQTRACSLSKC-------- 430
Query: 323 RSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFC- 381
D R R++ G WSPWS CS TCG G TR R C
Sbjct: 431 --------DTRIRQDGG-----------------WSHWSPWSSCSVTCGVGNITRIRLCN 465
Query: 382 --VSSSYSTQCSGPLREQRLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRDRTRTCR-- 437
V C G RE + C A CP+ G W WSPWS C+ TC G R+RTR C
Sbjct: 466 SPVPQMGGKNCKGSGRETKAC-QGAPCPIDGRWSPWSPWSACTVTCAGGIRERTRVCNSP 524
Query: 438 PPQFGGNPCEGPEKQTKFCNIALCPGRAVDG 468
PQ+GG C G ++ + CN CP VDG
Sbjct: 525 EPQYGGKACVGDVQERQMCNKRSCP---VDG 552
Score = 78.6 bits (192), Expect = 5e-14
Identities = 63/205 (30%), Positives = 80/205 (39%), Gaps = 57/205 (27%)
Query: 247 CLTSLTQDRGGHGATGGWKLWSLWGECTRDCGGGLQTRTRTC-LPAPGVEGGGCEGVLEE 305
C T + QD GGW WS W C+ CG G TR R C P P + G C+G E
Sbjct: 430 CDTRIRQD-------GGWSHWSPWSSCSVTCGVGNITRIRLCNSPVPQMGGKNCKGSGRE 482
Query: 306 GRQCNREACGPAGRTSSRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSV 365
+ C C GR S WSPWS
Sbjct: 483 TKACQGAPCPIDGRWS-------------------------------------PWSPWSA 505
Query: 366 CSSTCGEGWQTRTRFCVSSS---YSTQCSGPLREQRLCNNSAVCPVHGAW-DEWSPWSLC 421
C+ TC G + RTR C S C G ++E+++CN + CPV G + P + C
Sbjct: 506 CTVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCNKRS-CPVDGCLSNPCFPGAQC 564
Query: 422 SSTCGRGFRDRTRTCR--PPQFGGN 444
SS F D + +C P F GN
Sbjct: 565 SS-----FPDGSWSCGSCPVGFLGN 584
Score = 59.7 bits (143), Expect = 2e-08
Identities = 31/85 (36%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 243 GPENCLTSLTQDRGGHGAT----GGWKLWSLWGECTRDCGGGLQTRTRTC-LPAPGVEGG 297
G +NC S + + GA G W WS W CT C GG++ RTR C P P G
Sbjct: 472 GGKNCKGSGRETKACQGAPCPIDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGK 531
Query: 298 GCEGVLEEGRQCNREACGPAGRTSS 322
C G ++E + CN+ +C G S+
Sbjct: 532 ACVGDVQERQMCNKRSCPVDGCLSN 556
>gi|40317626 thrombospondin 1 precursor [Homo sapiens]
Length = 1170
Score = 158 bits (399), Expect = 5e-38
Identities = 87/238 (36%), Positives = 113/238 (47%), Gaps = 21/238 (8%)
Query: 400 CNNSAV-----CP-------VHGAWDEWSPWSLCSSTCGRGFRDRTRTCRPPQFGGNPCE 447
C+N+ V CP W WS W+ CS++CG G + R R+C N CE
Sbjct: 358 CSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLN---NRCE 414
Query: 448 GPEKQTKFCNIALCPGR-AVDGNWNEWSSWSACSASCSQGRQQRTRECNGPS--YGGAEC 504
G QT+ C+I C R DG W+ WS WS+CS +C G R R CN PS G C
Sbjct: 415 GSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPC 474
Query: 505 QGHWVETRDCFLQQCPVDGKWQAWASWGSCSVTCGAGSQRRERVCSGPF--FGGAACQGP 562
+G ET+ C CP++G W W+ W CSVTCG G Q+R R+C+ P FGG C G
Sbjct: 475 EGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGD 534
Query: 563 QDEYRQCGTQRCPEPHEICDEDNFGAVIWKETPAGEVAAVRCPRNATGLILRRCELDE 620
E + C Q CP F V P G CP +G ++ ++DE
Sbjct: 535 VTENQICNKQDCP-IDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDE 591
Score = 151 bits (381), Expect = 6e-36
Identities = 85/232 (36%), Positives = 105/232 (45%), Gaps = 41/232 (17%)
Query: 354 DPAAEEWSPWSV---CSSTCGEGWQTRTRFCVSSSYSTQCSGPLREQRLCNNSAV---CP 407
D A + WSPWS CS++CG G Q R R C S + +C G + R C+
Sbjct: 376 DSADDGWSPWSEWTSCSTSCGNGIQQRGRSC--DSLNNRCEGSSVQTRTCHIQECDKRFK 433
Query: 408 VHGAWDEWSPWSLCSSTCGRGFRDRTRTCR--PPQFGGNPCEGPEKQTKFCNIALCPGRA 465
G W WSPWS CS TCG G R R C PQ G PCEG ++TK C CP
Sbjct: 434 QDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACP--- 490
Query: 466 VDGNWNEWSSWSACSASCSQGRQQRTRECNGPS--YGGAECQGHWVETRDCFLQQCPVDG 523
++G W WS W CS +C G Q+R+R CN P+ +GG +C G E + C Q CP+DG
Sbjct: 491 INGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDG 550
Query: 524 KWQAWASWGSCSVTCGAGSQRRERVCSGPFFGGAACQGPQDEYRQCGTQRCP 575
S P F G C D +CG CP
Sbjct: 551 ------------------------CLSNPCFAGVKCTSYPDGSWKCGA--CP 576
Score = 133 bits (335), Expect = 1e-30
Identities = 76/214 (35%), Positives = 95/214 (44%), Gaps = 46/214 (21%)
Query: 260 ATGGWKLWSLWGECTRDCGGGLQTRTRTCLPAPGVEGGGCEGVLEEGRQCNREACGPAGR 319
A GW WS W C+ CG G+Q R R+C CEG + R C+ + C
Sbjct: 378 ADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSL----NNRCEGSSVQTRTCHIQEC----- 428
Query: 320 TSSRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTR 379
D R +++ G WSPWS CS TCG+G TR R
Sbjct: 429 -----------DKRFKQDGG-----------------WSHWSPWSSCSVTCGDGVITRIR 460
Query: 380 FCVSSS---YSTQCSGPLREQRLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRDRTRTC 436
C S S C G RE + C A CP++G W WSPW +CS TCG G + R+R C
Sbjct: 461 LCNSPSPQMNGKPCEGEARETKACKKDA-CPINGGWGPWSPWDICSVTCGGGVQKRSRLC 519
Query: 437 R--PPQFGGNPCEGPEKQTKFCNIALCPGRAVDG 468
PQFGG C G + + CN CP +DG
Sbjct: 520 NNPTPQFGGKDCVGDVTENQICNKQDCP---IDG 550
Score = 108 bits (269), Expect = 5e-23
Identities = 66/215 (30%), Positives = 92/215 (42%), Gaps = 23/215 (10%)
Query: 389 QCSGPLREQRLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRDRTRTCRPPQFGGNPCEG 448
+ + LR LC ++ V + +EW+ S C ++ C+ PC
Sbjct: 307 ELANELRRPPLCYHNGVQYRNN--EEWTVDSCTECHC----QNSVTICKKVSCPIMPCSN 360
Query: 449 PEKQTKFCNIALCPGRAVDGNWNEWSSWSACSASCSQGRQQRTRECNGPSYGGAECQGHW 508
C P + D W+ WS W++CS SC G QQR R C+ + C+G
Sbjct: 361 ATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLN---NRCEGSS 417
Query: 509 VETRDCFLQQC----PVDGKWQAWASWGSCSVTCGAGSQRRERVCSGPF--FGGAACQGP 562
V+TR C +Q+C DG W W+ W SCSVTCG G R R+C+ P G C+G
Sbjct: 418 VQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGE 477
Query: 563 QDEYRQCGTQRCP--------EPHEICDEDNFGAV 589
E + C CP P +IC G V
Sbjct: 478 ARETKACKKDACPINGGWGPWSPWDICSVTCGGGV 512
>gi|148806925 EGF, latrophilin and seven transmembrane domain
containing 1 [Homo sapiens]
Length = 690
Score = 158 bits (399), Expect = 5e-38
Identities = 138/549 (25%), Positives = 239/549 (43%), Gaps = 66/549 (12%)
Query: 693 MTEIFRRAYYSPTPGDVQNFVQIL---SNLLAEENRDKWEEAQLAGPNAKELFRLVEDFV 749
+ E++R + +P D+ +++IL S+LL +N + L+ E + V +FV
Sbjct: 143 LQEVYRNSVTDLSPTDIITYIEILAESSSLLGYKNNTISAKDTLSNSTLTEFVKTVNNFV 202
Query: 750 DVIGFRMKD--------------LRDAYQVTDNLVLSIHKLPA--SGATDIS-----FPM 788
F + D + Q T + S K + +TDI+ F
Sbjct: 203 QRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRISQSFQKTTEFDTNSTDIALKVFFFDS 262
Query: 789 KGWRATGDWAKVPEDRVTVSKSVFSTGLTEADEASVFVVGTVLYRNLGSFLALQRNTTV- 847
+ + D + ++F D V V Y+++G L+ N +
Sbjct: 263 YNMKHIHPHMNMDGDYI----NIFPKRKAAYDSNGNVAVAFVYYKSIGPLLSSSDNFLLK 318
Query: 848 ------------LNSKVISVTVKPPPRSLRTPLEIEFAHMYNGTTNQ---TCILWDETDV 892
+ S VISV++ P +L +I F + T++ C W+
Sbjct: 319 PQNYDNSEEEERVISSVISVSMSSNPPTLYELEKITFTLSHRKVTDRYRSLCAFWNY--- 375
Query: 893 PSSSAPPQLGPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADANMEKATLPSVTLI 952
S G WS GC + T C C+ L+ FAIL ++ + +T I
Sbjct: 376 ---SPDTMNGSWSSEGCELTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYNI--LTRI 430
Query: 953 VGCGVSSLTLLMLVIIYVSVWRY--IRSERSVILINFCLSIISSNALILIGQTQTRNKVV 1010
G+ ++L+ L I + W + I+S R+ I N C S+ + + L+G NK+
Sbjct: 431 TQLGII-ISLICLAICIFTFWFFSEIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLF 489
Query: 1011 CTLVAAFLHFFFLSSFCWVLTEAWQSYMAVTGHLRNR-LIRKRFLCLGWGLPALVVAISV 1069
C+++A LH+FFL++F W+ E Y+ V G + N+ + K F G+ PA+V V
Sbjct: 490 CSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVIYNKGFLHKNFYIFGYLSPAVV----V 545
Query: 1070 GFTKAKG---YSTMNYCWLSLEGGLLYAFVGPAAAVVLVNMV-IGILVFNKLVSKDGI-T 1124
GF+ A G Y T CWLS E +++F+GPA ++LVN++ G++++ G+
Sbjct: 546 GFSAALGYRYYGTTKVCWLSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKP 605
Query: 1125 DKKLKERAGASLWSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVH 1184
+ E + + +L LL TW+ VL V S + LF V ++ +G I +
Sbjct: 606 EVSCFENIRSCARGALALLFLLGTTWIFGVLHVV-HASVVTAYLFTVSNAFQGMFIFLFL 664
Query: 1185 CILRREVQD 1193
C+L R++Q+
Sbjct: 665 CVLSRKIQE 673
>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
sapiens]
Length = 652
Score = 155 bits (392), Expect = 3e-37
Identities = 110/403 (27%), Positives = 198/403 (49%), Gaps = 32/403 (7%)
Query: 808 SKSVFSTGLTEADEASVFVVGTVLYRNLGSFLAL-------QRNTTVLNSKVISVTVKPP 860
S + + + + D + + Y +LG+ + +++ LNS+V+S + P
Sbjct: 218 SMDIRCSDIIQGDTQGPSAIAFISYSSLGNIINATFFEEMDKKDQVYLNSQVVSAAIGPK 277
Query: 861 PR-SLRTPLEIEFAH--MYNGTTNQTCILWDETDVPSSSAPPQLGPWSWRGCRTVPLDAL 917
SL + + F H M T C+ W T S WS GC + ++
Sbjct: 278 RNVSLSKSVTLTFQHVKMTPSTKKVFCVYWKSTGQGSQ--------WSRDGCFLIHVNKS 329
Query: 918 RTRCLCDRLSTFAILAQLSADANMEKATLPSVTLIVGCGVSSLTLLMLVIIYVSVWRYIR 977
T C C LS+FA+L L++ E+ + +V VG VS L LL+ + ++ + + IR
Sbjct: 330 HTMCNCSHLSSFAVLMALTSQ---EEDPVLTVITYVGLSVSLLCLLLAALTFL-LCKAIR 385
Query: 978 SERSVILINFCLSIISSNALILIGQTQTRNKVVCTLVAAFLHFFFLSSFCWVLTEAWQSY 1037
+ + + + L + ++ L L+G +T KV+C+++A LH+ +L++F W+L E +
Sbjct: 386 NTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLF 445
Query: 1038 M------AVTGHLRNRLIRKRFLCLGWGLPALVVAISVGFTKAKGYSTMNYCWLSLEGGL 1091
+ V NRL++ +G+G+PA+ VAIS + Y T + CWL L+ G
Sbjct: 446 LTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAA-SWPHLYGTADRCWLHLDQGF 504
Query: 1092 LYAFVGPAAAVVLVNMVIGILVFNKLVSKDGITDKKLK--ERAGASLWSSCVVLPLLALT 1149
+++F+GP A+ N+V+ ILVF L K + ++ + + + L +L T
Sbjct: 505 MWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCT 564
Query: 1150 WMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQ 1192
W +L V + + LF + +SL+GF I +V+C+L ++VQ
Sbjct: 565 WCLGLLQV-GPAAQVMAYLFTIINSLQGFFIFLVYCLLSQQVQ 606
>gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
Length = 3080
Score = 151 bits (381), Expect = 6e-36
Identities = 157/643 (24%), Positives = 278/643 (43%), Gaps = 80/643 (12%)
Query: 587 GAVIWKETPAGEVAAVRCPRNATGLILRRCELD-EEGIAYWEPPTYIRCVSIDYRNIQMM 645
G W T E A RC +N G R C + G + WE P + +C + +++
Sbjct: 2397 GTYKWLLTNPTETAQTRCIKNEDGNATRFCSISINTGKSQWEKPKFKQCKLLQELPDKIV 2456
Query: 646 TREHLAKAQRGLPGEGVSEVIQTLVEISQD-GTSYSGDLLSTIDVLRNMTEIFRRAYYSP 704
++ + E V+E I L+ S G + ++S I + EI +
Sbjct: 2457 DLANITISDEN--AEDVAEHILNLINESPALGKEETKIIVSKISDISQCDEISMNLTHV- 2513
Query: 705 TPGDVQNFVQILSNLLAEENRDKWEEAQLAGPNAKELFRLVE------DF------VDVI 752
+QI++ +L ++N + +++ E+ R++E +F + V
Sbjct: 2514 -------MLQIINVVLEKQNNSASDLHEISN----EILRIIERTGHKMEFSGQIANLTVA 2562
Query: 753 GFRMKDLRDAYQVTDNLVLSIHKLPASGATDI---SFPMKGWRATGDWAKVPEDRVTVSK 809
G + LR + D + SIH +I + P+ G A+ K +R+ +S
Sbjct: 2563 GLALAVLRGDHTF-DGMAFSIHSYEEGTDPEIFLGNVPVGGILASIYLPKSLTERIPLSN 2621
Query: 810 SVFSTGLTEADEASVFVVGTVLYRNLG--SFLALQRNTTVLNSKVISVTVKPPP--RSLR 865
+ T+L+ G S + T L + V+S ++ ++L
Sbjct: 2622 -----------------LQTILFNFFGQTSLFKTKNVTKALTTYVVSASISDDMFIQNLA 2664
Query: 866 TPLEIEFAHMYNGTTNQT---CILWDETDVPSSSAPPQLGPWSWRGCRTVPLDALRTRCL 922
P+ I H+ G N C WD + LG W+ GC+ + T C
Sbjct: 2665 DPVVITLQHI-GGNQNYGQVHCAFWDFENNNG------LGGWNSSGCKVKETNVNYTICQ 2717
Query: 923 CDRLSTFAILAQLSADA--NMEKATLPSVTLIVGCGVSSLTLLMLVIIYVSVWRYIRSER 980
CD L+ F +L LS ++ + L +T GCG+SS+ L + V+ Y++ + +
Sbjct: 2718 CDHLTHFGVLMDLSRSTVDSVNEQILALITY-TGCGISSIFLGVAVVTYIAFHKLRKDYP 2776
Query: 981 SVILINFCLSIISSNALILIGQ--TQTRNKVVCTLVAAFLHFFFLSSFCWVLTEAWQSYM 1038
+ ILIN C +++ N + LI + + VC A LH+F L SF W+ EA Y+
Sbjct: 2777 AKILINLCTALLMLNLVFLINSWLSSFQKVGVCITAAVALHYFLLVSFTWMGLEAVHMYL 2836
Query: 1039 AVTG----HLRNRLIRKRFLCLGWGLPALVVAISVGFTKAKGYSTMN----YCWLSLEGG 1090
A+ ++ N ++ +F +GWG+PA++VAI+V K Y T++ +CW+ +
Sbjct: 2837 ALVKVFNIYIPNYIL--KFCLVGWGIPAIMVAITVS-VKKDLYGTLSPTTPFCWIKDDSI 2893
Query: 1091 LLYAFVGPAAAVVLVNMVIGILVFNKLVSKDGITDKKLKERAGASLWSSCVVLPLLALTW 1150
+ V + L+N+ + V +L S K ++ L + + LL LTW
Sbjct: 2894 FYISVVAYFCLIFLMNLSMFCTVLVQLNSVKSQIQKTRRKMILHDLKGTMSLTFLLGLTW 2953
Query: 1151 MSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQD 1193
A A R+ F LFA+F++L+GF I + HC+++ V++
Sbjct: 2954 GFAFFAWGPMRN-FFLYLFAIFNTLQGFFIFVFHCVMKESVRE 2995
>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
Length = 786
Score = 150 bits (379), Expect = 9e-36
Identities = 95/297 (31%), Positives = 157/297 (52%), Gaps = 12/297 (4%)
Query: 902 GPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADANMEKATLPSVTLIVGCGVSSLT 961
G W+ GC+ + T C C LS+FAIL A ++E L +T VG +S
Sbjct: 457 GHWATEGCQVLGSKNGSTTCQCSHLSSFAILM---AHYDVEDWKLTLITR-VGLALSLFC 512
Query: 962 LLMLVIIYVSVWRYIRSERSVILINFCLSIISSNALILIGQTQTRNKVV--CTLVAAFLH 1019
LL+ ++ ++ V R I+ R+ I ++ C+ + + + L G +V C LVA LH
Sbjct: 513 LLLCILTFLLV-RPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLH 571
Query: 1020 FFFLSSFCWVLTEAWQSYMAVTGHLRNRLIRKRFLCL-GWGLPALVVAISVGFTKAKGYS 1078
+ FL++FCW+ E + Y V + + + R+LCL G+G+P L+V +S +KGY
Sbjct: 572 YCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIY-SKGYG 630
Query: 1079 TMNYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNKLVSK--DGITDKKLKERAGASL 1136
YCWL E G L++F+GP ++L N VI + KL K + D K ++A A
Sbjct: 631 RPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALT 690
Query: 1137 WSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQD 1193
++ L LL TW+ L + D RS + +F + + L+G + ++HC+L ++V++
Sbjct: 691 ITAIAQLFLLGCTWVFG-LFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVRE 746
>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
Length = 742
Score = 150 bits (379), Expect = 9e-36
Identities = 95/297 (31%), Positives = 157/297 (52%), Gaps = 12/297 (4%)
Query: 902 GPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADANMEKATLPSVTLIVGCGVSSLT 961
G W+ GC+ + T C C LS+FAIL A ++E L +T VG +S
Sbjct: 413 GHWATEGCQVLGSKNGSTTCQCSHLSSFAILM---AHYDVEDWKLTLITR-VGLALSLFC 468
Query: 962 LLMLVIIYVSVWRYIRSERSVILINFCLSIISSNALILIGQTQTRNKVV--CTLVAAFLH 1019
LL+ ++ ++ V R I+ R+ I ++ C+ + + + L G +V C LVA LH
Sbjct: 469 LLLCILTFLLV-RPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLH 527
Query: 1020 FFFLSSFCWVLTEAWQSYMAVTGHLRNRLIRKRFLCL-GWGLPALVVAISVGFTKAKGYS 1078
+ FL++FCW+ E + Y V + + + R+LCL G+G+P L+V +S +KGY
Sbjct: 528 YCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIY-SKGYG 586
Query: 1079 TMNYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNKLVSK--DGITDKKLKERAGASL 1136
YCWL E G L++F+GP ++L N VI + KL K + D K ++A A
Sbjct: 587 RPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALT 646
Query: 1137 WSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQD 1193
++ L LL TW+ L + D RS + +F + + L+G + ++HC+L ++V++
Sbjct: 647 ITAIAQLFLLGCTWVFG-LFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVRE 702
>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
Length = 835
Score = 150 bits (379), Expect = 9e-36
Identities = 95/297 (31%), Positives = 157/297 (52%), Gaps = 12/297 (4%)
Query: 902 GPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADANMEKATLPSVTLIVGCGVSSLT 961
G W+ GC+ + T C C LS+FAIL A ++E L +T VG +S
Sbjct: 506 GHWATEGCQVLGSKNGSTTCQCSHLSSFAILM---AHYDVEDWKLTLITR-VGLALSLFC 561
Query: 962 LLMLVIIYVSVWRYIRSERSVILINFCLSIISSNALILIGQTQTRNKVV--CTLVAAFLH 1019
LL+ ++ ++ V R I+ R+ I ++ C+ + + + L G +V C LVA LH
Sbjct: 562 LLLCILTFLLV-RPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLH 620
Query: 1020 FFFLSSFCWVLTEAWQSYMAVTGHLRNRLIRKRFLCL-GWGLPALVVAISVGFTKAKGYS 1078
+ FL++FCW+ E + Y V + + + R+LCL G+G+P L+V +S +KGY
Sbjct: 621 YCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIY-SKGYG 679
Query: 1079 TMNYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNKLVSK--DGITDKKLKERAGASL 1136
YCWL E G L++F+GP ++L N VI + KL K + D K ++A A
Sbjct: 680 RPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALT 739
Query: 1137 WSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQD 1193
++ L LL TW+ L + D RS + +F + + L+G + ++HC+L ++V++
Sbjct: 740 ITAIAQLFLLGCTWVFG-LFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVRE 795
>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
Length = 874
Score = 150 bits (378), Expect = 1e-35
Identities = 102/304 (33%), Positives = 159/304 (52%), Gaps = 14/304 (4%)
Query: 902 GPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSAD--ANMEKATLPSVTLIVGCGVSS 959
G WS GC + + C C L+ FAIL Q+ A + L S++ VGC +S
Sbjct: 520 GVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVALSSISY-VGCSLSV 578
Query: 960 LTLLMLVIIY--VSVWRYIRSERSVILINFCLSIISSNALILIGQTQTRNKVVCTLVAAF 1017
L L+ ++ + +S IR++R I N +++ + L+LI C ++A
Sbjct: 579 LCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEPGTTPCQVMAVL 638
Query: 1018 LHFFFLSSFCWVLTEAWQSYMAVTGHLRNRLIRKRFLC-LGWGLPALVVAISVGFTKAKG 1076
LH+FFLS+F W+L E Y V + + R+ +GWG P L+ IS+ F
Sbjct: 639 LHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGFPLLICIISLSFA-MDS 697
Query: 1077 YSTMNYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILV-FNKLVSKDGITDKKLKERAGA- 1134
Y T N CWLSL G ++AFV PA V++VN IGIL+ +++S+ + K+ A
Sbjct: 698 YGTSNNCWLSLASGAIWAFVAPALFVIVVN--IGILIAVTRVISQISADNYKIHGDPSAF 755
Query: 1135 --SLWSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQ 1192
+ + V+LP+L +W+ VLAV + + +FQ +FA +SL+G I + HC+L EV+
Sbjct: 756 KLTAKAVAVLLPILGTSWVFGVLAV-NGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEVR 814
Query: 1193 DAVK 1196
A K
Sbjct: 815 AAFK 818
>gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo sapiens]
Length = 1079
Score = 146 bits (369), Expect = 1e-34
Identities = 155/636 (24%), Positives = 269/636 (42%), Gaps = 50/636 (7%)
Query: 581 CDEDNFGAVIWKETPAGEVAAVRCPRNATGLILRRCELDEEGIAYWEPPTYIRCVSIDYR 640
C ED + W T AG VA CP + G++ R C D W P + D R
Sbjct: 431 CPEDA-SVLTWNVTKAGHVAQAPCPESKRGIVRRLCGAD----GVWGP---VHSSCTDAR 482
Query: 641 NIQMMTREHLAKAQRGLPGEGVSEVIQTLVEISQDGTSYSGDLLSTIDVLRNMTEIFRRA 700
+ + TR L +A +G P E V +++ L + + +S S DLL+ + ++ + ++ A
Sbjct: 483 LLALFTRTKLLQAGQGSPAEEVPQILAQLPGQAAEASSPS-DLLTLLSTMKYVAKVVAEA 541
Query: 701 YYSPTPGDVQNFVQILSNLLAEENRDKWEEAQLAGPNAKELFRLVEDFVDVIGFRMKDLR 760
++N + +L + R W AQ P A L + + +D
Sbjct: 542 RIQLDRRALKNLLIATDKVLDMDTRSLWTLAQARKPWAGSTLLLAVETL-ACSLCPQDHP 600
Query: 761 DAYQVTDNLVLSIHKLPASGAT-DISFPMKG--WRATGDWAKVPEDRVTVSKSVFSTGLT 817
A+ + + L+ S P A ISFP + + P R S+ S L
Sbjct: 601 FAFSLPNVLLQSQLFGPTFPADYSISFPTRPPLQAQIPRHSLAPLVRNGTEISITSLVLR 660
Query: 818 EADEASVFVVGTVLYRNLGSFLALQRNTTVLNSKVISVTVKPPPRSLRTPLEIEFAHMYN 877
+ D +L N G L T VIS+ S + + ++F N
Sbjct: 661 KLDH--------LLPSNYGQGLGDSLYATPGLVLVISIMAGDRAFS-QGEVIMDFG---N 708
Query: 878 GTTNQTCILWDETDVPSSSAPPQLGPWSWRGCRTVPLDALRT-RCLCDRLSTFAILAQLS 936
+ C+ WD + G WS GC+ A T +CLC L+ F++L +S
Sbjct: 709 TDGSPHCVFWDHSLFQGR------GGWSKEGCQAQVASASPTAQCLCQHLTAFSVL--MS 760
Query: 937 ADANMEKATLPSVTLIVGCGVSSLTLLMLVIIYVSVWRYIRSE-----RSVILINFCLSI 991
E+ L +T VG G S L LL+ + +Y VWR + R L+N +
Sbjct: 761 PHTVPEEPALALLTQ-VGLGASILALLVCLGVYWLVWRVVVRNKISYFRHAALLNMVFCL 819
Query: 992 ISSNALILIGQ--TQTRNKVVCTLVAAFLHFFFLSSFCWVLTEAW---QSYMAVTGHLRN 1046
++++ L + +C A HF +L++F W+L +A + V L
Sbjct: 820 LAADTCFLGAPFLSPGPRSPLCLAAAFLCHFLYLATFFWMLAQALVLAHQLLFVFHQLAK 879
Query: 1047 RLIRKRFLCLGWGLPALVVAISVGFTKAKG-YSTMNYCWLSLEGGLLYAFVGPAAAVVLV 1105
+ + LG+ P + +++G +G Y CWL +GG LY FVGP A++ V
Sbjct: 880 HRVLPLMVLLGYLCPLGLAGVTLGLYLPQGQYLREGECWLDGKGGALYTFVGPVLAIIGV 939
Query: 1106 NMVIGILVFNKLVS---KDGITDKKLKERAGASLWSSCVVLPLLALTWMSAVLAVTDRRS 1162
N ++ + KL+ +G +K + G + + ++ P+ LTW + + + S
Sbjct: 940 NGLVLAMAMLKLLRPSLSEGPPAEKRQALLGV-IKALLILTPIFGLTWGLGLATLLEEVS 998
Query: 1163 ALFQILFAVFDSLEGFVIVMVHCILRREVQDAVKCR 1198
+ +F + ++L+G I++ C++ R++Q+A++ R
Sbjct: 999 TVPHYIFTILNTLQGVFILLFGCLMDRKIQEALRKR 1034
>gi|223556014 G-protein coupled receptor 113 isoform 2 [Homo sapiens]
Length = 997
Score = 146 bits (369), Expect = 1e-34
Identities = 155/636 (24%), Positives = 269/636 (42%), Gaps = 50/636 (7%)
Query: 581 CDEDNFGAVIWKETPAGEVAAVRCPRNATGLILRRCELDEEGIAYWEPPTYIRCVSIDYR 640
C ED + W T AG VA CP + G++ R C D W P + D R
Sbjct: 362 CPEDA-SVLTWNVTKAGHVAQAPCPESKRGIVRRLCGAD----GVWGP---VHSSCTDAR 413
Query: 641 NIQMMTREHLAKAQRGLPGEGVSEVIQTLVEISQDGTSYSGDLLSTIDVLRNMTEIFRRA 700
+ + TR L +A +G P E V +++ L + + +S S DLL+ + ++ + ++ A
Sbjct: 414 LLALFTRTKLLQAGQGSPAEEVPQILAQLPGQAAEASSPS-DLLTLLSTMKYVAKVVAEA 472
Query: 701 YYSPTPGDVQNFVQILSNLLAEENRDKWEEAQLAGPNAKELFRLVEDFVDVIGFRMKDLR 760
++N + +L + R W AQ P A L + + +D
Sbjct: 473 RIQLDRRALKNLLIATDKVLDMDTRSLWTLAQARKPWAGSTLLLAVETL-ACSLCPQDHP 531
Query: 761 DAYQVTDNLVLSIHKLPASGAT-DISFPMKG--WRATGDWAKVPEDRVTVSKSVFSTGLT 817
A+ + + L+ S P A ISFP + + P R S+ S L
Sbjct: 532 FAFSLPNVLLQSQLFGPTFPADYSISFPTRPPLQAQIPRHSLAPLVRNGTEISITSLVLR 591
Query: 818 EADEASVFVVGTVLYRNLGSFLALQRNTTVLNSKVISVTVKPPPRSLRTPLEIEFAHMYN 877
+ D +L N G L T VIS+ S + + ++F N
Sbjct: 592 KLDH--------LLPSNYGQGLGDSLYATPGLVLVISIMAGDRAFS-QGEVIMDFG---N 639
Query: 878 GTTNQTCILWDETDVPSSSAPPQLGPWSWRGCRTVPLDALRT-RCLCDRLSTFAILAQLS 936
+ C+ WD + G WS GC+ A T +CLC L+ F++L +S
Sbjct: 640 TDGSPHCVFWDHSLFQGR------GGWSKEGCQAQVASASPTAQCLCQHLTAFSVL--MS 691
Query: 937 ADANMEKATLPSVTLIVGCGVSSLTLLMLVIIYVSVWRYIRSE-----RSVILINFCLSI 991
E+ L +T VG G S L LL+ + +Y VWR + R L+N +
Sbjct: 692 PHTVPEEPALALLTQ-VGLGASILALLVCLGVYWLVWRVVVRNKISYFRHAALLNMVFCL 750
Query: 992 ISSNALILIGQ--TQTRNKVVCTLVAAFLHFFFLSSFCWVLTEAW---QSYMAVTGHLRN 1046
++++ L + +C A HF +L++F W+L +A + V L
Sbjct: 751 LAADTCFLGAPFLSPGPRSPLCLAAAFLCHFLYLATFFWMLAQALVLAHQLLFVFHQLAK 810
Query: 1047 RLIRKRFLCLGWGLPALVVAISVGFTKAKG-YSTMNYCWLSLEGGLLYAFVGPAAAVVLV 1105
+ + LG+ P + +++G +G Y CWL +GG LY FVGP A++ V
Sbjct: 811 HRVLPLMVLLGYLCPLGLAGVTLGLYLPQGQYLREGECWLDGKGGALYTFVGPVLAIIGV 870
Query: 1106 NMVIGILVFNKLVS---KDGITDKKLKERAGASLWSSCVVLPLLALTWMSAVLAVTDRRS 1162
N ++ + KL+ +G +K + G + + ++ P+ LTW + + + S
Sbjct: 871 NGLVLAMAMLKLLRPSLSEGPPAEKRQALLGV-IKALLILTPIFGLTWGLGLATLLEEVS 929
Query: 1163 ALFQILFAVFDSLEGFVIVMVHCILRREVQDAVKCR 1198
+ +F + ++L+G I++ C++ R++Q+A++ R
Sbjct: 930 TVPHYIFTILNTLQGVFILLFGCLMDRKIQEALRKR 965
>gi|141802362 G-protein coupled receptor 113 isoform 3 [Homo sapiens]
Length = 873
Score = 146 bits (369), Expect = 1e-34
Identities = 155/636 (24%), Positives = 269/636 (42%), Gaps = 50/636 (7%)
Query: 581 CDEDNFGAVIWKETPAGEVAAVRCPRNATGLILRRCELDEEGIAYWEPPTYIRCVSIDYR 640
C ED + W T AG VA CP + G++ R C D W P + D R
Sbjct: 232 CPEDA-SVLTWNVTKAGHVAQAPCPESKRGIVRRLCGAD----GVWGP---VHSSCTDAR 283
Query: 641 NIQMMTREHLAKAQRGLPGEGVSEVIQTLVEISQDGTSYSGDLLSTIDVLRNMTEIFRRA 700
+ + TR L +A +G P E V +++ L + + +S S DLL+ + ++ + ++ A
Sbjct: 284 LLALFTRTKLLQAGQGSPAEEVPQILAQLPGQAAEASSPS-DLLTLLSTMKYVAKVVAEA 342
Query: 701 YYSPTPGDVQNFVQILSNLLAEENRDKWEEAQLAGPNAKELFRLVEDFVDVIGFRMKDLR 760
++N + +L + R W AQ P A L + + +D
Sbjct: 343 RIQLDRRALKNLLIATDKVLDMDTRSLWTLAQARKPWAGSTLLLAVETL-ACSLCPQDHP 401
Query: 761 DAYQVTDNLVLSIHKLPASGAT-DISFPMKG--WRATGDWAKVPEDRVTVSKSVFSTGLT 817
A+ + + L+ S P A ISFP + + P R S+ S L
Sbjct: 402 FAFSLPNVLLQSQLFGPTFPADYSISFPTRPPLQAQIPRHSLAPLVRNGTEISITSLVLR 461
Query: 818 EADEASVFVVGTVLYRNLGSFLALQRNTTVLNSKVISVTVKPPPRSLRTPLEIEFAHMYN 877
+ D +L N G L T VIS+ S + + ++F N
Sbjct: 462 KLDH--------LLPSNYGQGLGDSLYATPGLVLVISIMAGDRAFS-QGEVIMDFG---N 509
Query: 878 GTTNQTCILWDETDVPSSSAPPQLGPWSWRGCRTVPLDALRT-RCLCDRLSTFAILAQLS 936
+ C+ WD + G WS GC+ A T +CLC L+ F++L +S
Sbjct: 510 TDGSPHCVFWDHSLFQGR------GGWSKEGCQAQVASASPTAQCLCQHLTAFSVL--MS 561
Query: 937 ADANMEKATLPSVTLIVGCGVSSLTLLMLVIIYVSVWRYIRSE-----RSVILINFCLSI 991
E+ L +T VG G S L LL+ + +Y VWR + R L+N +
Sbjct: 562 PHTVPEEPALALLTQ-VGLGASILALLVCLGVYWLVWRVVVRNKISYFRHAALLNMVFCL 620
Query: 992 ISSNALILIGQ--TQTRNKVVCTLVAAFLHFFFLSSFCWVLTEAW---QSYMAVTGHLRN 1046
++++ L + +C A HF +L++F W+L +A + V L
Sbjct: 621 LAADTCFLGAPFLSPGPRSPLCLAAAFLCHFLYLATFFWMLAQALVLAHQLLFVFHQLAK 680
Query: 1047 RLIRKRFLCLGWGLPALVVAISVGFTKAKG-YSTMNYCWLSLEGGLLYAFVGPAAAVVLV 1105
+ + LG+ P + +++G +G Y CWL +GG LY FVGP A++ V
Sbjct: 681 HRVLPLMVLLGYLCPLGLAGVTLGLYLPQGQYLREGECWLDGKGGALYTFVGPVLAIIGV 740
Query: 1106 NMVIGILVFNKLVS---KDGITDKKLKERAGASLWSSCVVLPLLALTWMSAVLAVTDRRS 1162
N ++ + KL+ +G +K + G + + ++ P+ LTW + + + S
Sbjct: 741 NGLVLAMAMLKLLRPSLSEGPPAEKRQALLGV-IKALLILTPIFGLTWGLGLATLLEEVS 799
Query: 1163 ALFQILFAVFDSLEGFVIVMVHCILRREVQDAVKCR 1198
+ +F + ++L+G I++ C++ R++Q+A++ R
Sbjct: 800 TVPHYIFTILNTLQGVFILLFGCLMDRKIQEALRKR 835
>gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens]
Length = 910
Score = 139 bits (350), Expect = 2e-32
Identities = 135/566 (23%), Positives = 237/566 (41%), Gaps = 87/566 (15%)
Query: 662 VSEVIQTL-VEISQDGTSYSGDLLSTIDVLRNMTEIFRRAYYSPTPGDVQNFVQILSNLL 720
VS +Q L V I Q+ ++ G+L S + +L N++ + +++ + +++ + I N+L
Sbjct: 323 VSSFVQNLSVIIRQNPSTTVGNLASVVSILSNISSLSLASHFRVSNSTMEDVISIADNIL 382
Query: 721 AEENRDKW----EEAQLAGPNAKELFRLVEDFVDVIGFRMKDLR----------DAYQVT 766
+ W E + A E + V + R + Q+
Sbjct: 383 NSASVTNWTVLLREEKYASSRLLETLENISTLVPPTALPLNFSRKFIDWKGIPVNKSQLK 442
Query: 767 DNLVLSIHKLPASGATDISFPMKGWRATGDWAKVPEDRVTVSKSVFSTGLTEADEASVFV 826
I P + S P++G RV + F L E
Sbjct: 443 RGYSYQIKMCPQN----TSIPIRG-------------RVLIGSDQFQRSLPET------- 478
Query: 827 VGTVLYRNLGSFLALQRNTTV-LNSKVISVTVKPPPRSLRTPLEIEFAHMYNGTTNQTCI 885
+ ++ LG+ L + +N +N VIS ++ + + F+ + + + C+
Sbjct: 479 IISMASLTLGNILPVSKNGNAQVNGPVISTVIQ---NYSINEVFLFFSKIESNLSQPHCV 535
Query: 886 LWDETDVPSSSAPPQLGPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADANMEKAT 945
WD + + W+ GC V C C L++F+IL + +
Sbjct: 536 FWDFSHLQ----------WNDAGCHLVNETQDIVTCQCTHLTSFSILMSPFVPSTI---- 581
Query: 946 LPSVTLI--VGCGVSSLTLLMLVIIYVSVWRYIRSE-----RSVILINFCLSIISSNALI 998
P V I VG G+S +L++ +II W+ I+ R + ++N LS++ ++
Sbjct: 582 FPVVKWITYVGLGISIGSLILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWF 641
Query: 999 LIG---QTQTRNKVVCTLVAAFLHFFFLSSFCWVLTEAW---QSYMAVTGHLRNRLIRKR 1052
++G T VCT F HFF+LS F W+L + V H+ L+
Sbjct: 642 IVGATVDTTVNPSGVCTAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAV 701
Query: 1053 FLCLGWGLPALVVAISVGFTKAKG-YSTMNYCWLSLEGGL--LYAFVGPAAAVVLVNMVI 1109
CLG+G P ++ I++ T+ Y + CWL+ G L AFV PA A+V VN V+
Sbjct: 702 GFCLGYGCPLIISVITIAVTQPSNTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVV 761
Query: 1110 GILVFNKL--------VSKDGITDKKLKERAGASLWSSCVVLPLLALTWMSAVLAVTDRR 1161
+LV KL +S+D DK R G SL ++ PLL LTW + + D +
Sbjct: 762 VLLVLTKLWRPTVGERLSRD---DKATIIRVGKSL---LILTPLLGLTWGFGIGTIVDSQ 815
Query: 1162 SALFQILFAVFDSLEGFVIVMVHCIL 1187
+ + ++FA+ ++ +GF I+ +L
Sbjct: 816 NLAWHVIFALLNAFQGFFILCFGILL 841
>gi|23397681 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform a [Homo sapiens]
Length = 823
Score = 136 bits (342), Expect = 2e-31
Identities = 100/365 (27%), Positives = 179/365 (49%), Gaps = 26/365 (7%)
Query: 841 LQRNTTVLNSKVISVTVKP-PPRSLRTPLEIEFAHMYNGTTNQT-CILWDETDVPSSSAP 898
LQ + +L S VIS + ++L +P+ F+H + C+ W+
Sbjct: 437 LQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKVLCVFWEH-------GQ 489
Query: 899 PQLGPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADANMEKATLPSVTLIVGCGVS 958
G W+ GC T+ T C C LS+FA+L D E L +T + G VS
Sbjct: 490 NGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVL-MAHYDVQEEDPVLTVITYM-GLSVS 547
Query: 959 SLTLLMLVIIYVSVWRYIRSERSVILINFCLSIISSNALILIGQTQTRNKVVCTLVAAFL 1018
L LL+ + ++ + + I++ + + + L + ++ L L+ QT +KV+C+++A L
Sbjct: 548 LLCLLLAALTFL-LCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTL 606
Query: 1019 HFFFLSSFCWVLTEAWQSYM------AVTGHLRNRLIRKRFLCLGWGLPALVVAISVGFT 1072
H+ +L++ W+L EA ++ V NR ++K +G+G+PA+ VAIS +
Sbjct: 607 HYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAA-S 665
Query: 1073 KAKGYSTMNYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVF----NKLVSKDGITDKKL 1128
+ Y T + CWL E G ++ F+GP A+ VN+V+ ++ N+L S +
Sbjct: 666 RPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLR 725
Query: 1129 KERAGASLWSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILR 1188
R A + + L +L TW +L V + + LF + +SL+G I +V+C+L
Sbjct: 726 NTRMLA--FKATAQLFILGCTWCLGILQV-GPAARVMAYLFTIINSLQGVFIFLVYCLLS 782
Query: 1189 REVQD 1193
++V++
Sbjct: 783 QQVRE 787
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,248,936
Number of Sequences: 37866
Number of extensions: 4716353
Number of successful extensions: 115241
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1448
Number of HSP's successfully gapped in prelim test: 1185
Number of HSP's that attempted gapping in prelim test: 33605
Number of HSP's gapped (non-prelim): 29992
length of query: 1584
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1468
effective length of database: 13,855,062
effective search space: 20339231016
effective search space used: 20339231016
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.