Guide to the Human Genome
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Search of human proteins with 167466278

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|167466278 solute carrier family 5 (iodide transporter),
member 8 [Homo sapiens]
         (610 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|167466278 solute carrier family 5 (iodide transporter), membe...  1222   0.0  
gi|157671931 solute carrier family 5 (sodium/glucose cotransport...   648   0.0  
gi|4507035 solute carrier family 5 (sodium iodide symporter), me...   576   e-164
gi|10863879 solute carrier family 5 (sodium-dependent vitamin tr...   502   e-142
gi|109659839 solute carrier family 5 (sodium/glucose cotransport...   107   4e-23
gi|4507031 solute carrier family 5 (sodium/glucose cotransporter...   104   3e-22
gi|109659836 solute carrier family 5 (sodium/glucose cotransport...   104   3e-22
gi|14140236 solute carrier family 5 (low affinity glucose cotran...   100   7e-21
gi|17941285 solute carrier family 5 (sodium/glucose cotransporte...    99   1e-20
gi|4507033 solute carrier family 5 (sodium/glucose cotransporter...    95   2e-19
gi|110835708 solute carrier family 5 (inositol transporters), me...    94   5e-19
gi|206597483 solute carrier family 5 (sodium/glucose cotransport...    91   3e-18
gi|206597487 solute carrier family 5 (sodium/glucose cotransport...    78   2e-14
gi|11141885 solute carrier family 5 (choline transporter), membe...    67   5e-11
gi|239751877 PREDICTED: hypothetical protein XP_002348035 [Homo ...    34   0.45 
gi|207444687 solute carrier family 41, member 2 [Homo sapiens]         34   0.45 
gi|51702206 solute carrier family 41 member 1 [Homo sapiens]           32   1.3  
gi|45580709 unc-93 homolog B1 [Homo sapiens]                           32   2.2  
gi|4885441 solute carrier family 17 (sodium phosphate), member 4...    31   2.9  
gi|25014088 solute carrier family 34 (sodium phosphate), member ...    31   3.8  
gi|47933348 zinc finger, DHHC domain containing 13 isoform 2 [Ho...    30   5.0  
gi|47933346 zinc finger, DHHC domain containing 13 isoform 1 [Ho...    30   5.0  
gi|239508735 PREDICTED: hypothetical protein [Homo sapiens]            30   6.5  
gi|48717231 olfactory receptor, family 9, subfamily A, member 4 ...    30   8.5  

>gi|167466278 solute carrier family 5 (iodide transporter), member 8
           [Homo sapiens]
          Length = 610

 Score = 1222 bits (3163), Expect = 0.0
 Identities = 610/610 (100%), Positives = 610/610 (100%)

Query: 1   MDTPRGIGTFVVWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALS 60
           MDTPRGIGTFVVWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALS
Sbjct: 1   MDTPRGIGTFVVWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALS 60

Query: 61  LTASFMSAVTVLGTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLE 120
           LTASFMSAVTVLGTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLE
Sbjct: 61  LTASFMSAVTVLGTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLE 120

Query: 121 LRFNKCVRLCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLG 180
           LRFNKCVRLCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLG
Sbjct: 121 LRFNKCVRLCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLG 180

Query: 181 GLKAVIWTDVFQVGIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQRH 240
           GLKAVIWTDVFQVGIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQRH
Sbjct: 181 GLKAVIWTDVFQVGIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQRH 240

Query: 241 TFWTIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGLA 300
           TFWTIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGLA
Sbjct: 241 TFWTIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGLA 300

Query: 301 LYSRYHDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINAL 360
           LYSRYHDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINAL
Sbjct: 301 LYSRYHDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINAL 360

Query: 361 AAVTVEDLIKPYFRSLSERSLSWISQGMSVVYGALCIGMAALASLMGALLQAALSVFGMV 420
           AAVTVEDLIKPYFRSLSERSLSWISQGMSVVYGALCIGMAALASLMGALLQAALSVFGMV
Sbjct: 361 AAVTVEDLIKPYFRSLSERSLSWISQGMSVVYGALCIGMAALASLMGALLQAALSVFGMV 420

Query: 421 GGPLMGLFALGILVPFANSIGALVGLMAGFAISLWVGIGAQIYPPLPERTLPLHLDIQGC 480
           GGPLMGLFALGILVPFANSIGALVGLMAGFAISLWVGIGAQIYPPLPERTLPLHLDIQGC
Sbjct: 421 GGPLMGLFALGILVPFANSIGALVGLMAGFAISLWVGIGAQIYPPLPERTLPLHLDIQGC 480

Query: 481 NSTYNETNLMTTTEMPFTTSVFQIYNVQRTPLMDNWYSLSYLYFSTVGTLVTLLVGILVS 540
           NSTYNETNLMTTTEMPFTTSVFQIYNVQRTPLMDNWYSLSYLYFSTVGTLVTLLVGILVS
Sbjct: 481 NSTYNETNLMTTTEMPFTTSVFQIYNVQRTPLMDNWYSLSYLYFSTVGTLVTLLVGILVS 540

Query: 541 LSTGGRKQNLDPRYILTKEDFLSNFDIFKKKKHVLSYKSHPVEDGGTDNPAFNHIELNSD 600
           LSTGGRKQNLDPRYILTKEDFLSNFDIFKKKKHVLSYKSHPVEDGGTDNPAFNHIELNSD
Sbjct: 541 LSTGGRKQNLDPRYILTKEDFLSNFDIFKKKKHVLSYKSHPVEDGGTDNPAFNHIELNSD 600

Query: 601 QSGKSNGTRL 610
           QSGKSNGTRL
Sbjct: 601 QSGKSNGTRL 610


>gi|157671931 solute carrier family 5 (sodium/glucose
           cotransporter), member 12 [Homo sapiens]
          Length = 618

 Score =  648 bits (1671), Expect = 0.0
 Identities = 321/582 (55%), Positives = 418/582 (71%), Gaps = 16/582 (2%)

Query: 7   IGTFVVWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFM 66
           +  F VWDYVVFA +  IS+ IG+++A     + TS++FL+GGR+M+  PV LSLTASFM
Sbjct: 3   VKNFAVWDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFM 62

Query: 67  SAVTVLGTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRFNKC 126
           SAVTVLGTPSEVYRFGA F +F   Y FV+++++E+FLPVFY+ GITSTYEYL+LRFNK 
Sbjct: 63  SAVTVLGTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFNKP 122

Query: 127 VRLCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVI 186
           VR   TV++IVQTILYTG+V+YAPALALNQVTGFDLWG+V ATG+VCTFYCTLGGLKAV+
Sbjct: 123 VRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVV 182

Query: 187 WTDVFQVGIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQRHTFWTII 246
           WTD FQ+ +M+ GF +V+IQ     GG   +L  + +G RL+ ++F+ +PL+RHTFWTI 
Sbjct: 183 WTDAFQMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRHTFWTIT 242

Query: 247 IGGTFTWTSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGLALYSRYH 306
           +GGTFTW  IYGVNQS +QR ISCK+   AKL+LY NL+GLW IL C+VF GL +YS + 
Sbjct: 243 VGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCAVFSGLIMYSHFK 302

Query: 307 DCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINALAAVTVE 366
           DCDPWT+  +SAPDQLMPY V++I    PGLPGLFVACA+SGTLSTV+SSINALA VT E
Sbjct: 303 DCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASSINALATVTFE 362

Query: 367 DLIKPYFRSLSERSLSWISQGMSVVYGALCIGMAALASLMGALLQAALSVFGMVGGPLMG 426
           D +K  F  LS++  +WIS+G+ +++G +C  MA  AS+MG ++QA+LS+ GM GGP++G
Sbjct: 363 DFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSMAVAASVMGGVVQASLSIHGMCGGPMLG 422

Query: 427 LFALGILVPFANSIGALVGLMAGFAISLWVGIGAQIYPPLPERTLPLHLDIQGCNSTYNE 486
           LF+LGI+ PF N  GAL GL+ G  +S WV IGA IYP    +T PL L    C  +   
Sbjct: 423 LFSLGIVFPFVNWKGALGGLLTGITLSFWVAIGAFIYPAPASKTWPLPLSTDQCIKSN-- 480

Query: 487 TNLMTTTEMPFTTSVFQIYNVQRTPLMDNWYSLSYLYFSTVGTLVTLLVGILVSLSTGGR 546
              +T T  P  +S        R  + D WYS+SYLY+S VG L  ++ G+++SL T GR
Sbjct: 481 ---VTATGPPVLSS--------RPGIADTWYSISYLYYSAVGCLGCIVAGVIISLIT-GR 528

Query: 547 KQNLDPRYILTKEDFLSNFDIFKKKKHVLSYKSHPVEDGGTD 588
           ++  D + +L +   + N   F  KK+          D GT+
Sbjct: 529 QRGEDIQPLLIRP--VCNLFCFWSKKYKTLCWCGVQHDSGTE 568


>gi|4507035 solute carrier family 5 (sodium iodide symporter),
           member 5 [Homo sapiens]
          Length = 643

 Score =  576 bits (1485), Expect = e-164
 Identities = 283/546 (51%), Positives = 392/546 (71%), Gaps = 5/546 (0%)

Query: 9   TFVVWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSA 68
           TF  WDY VFA ML++S  IG++   A GGQ++++DF  GGRR+ A+PV LSL+ASFMSA
Sbjct: 11  TFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSA 70

Query: 69  VTVLGTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRFNKCVR 128
           V VLG PSE YR+G  F           V++A +F+PVFY+LG+TSTYEYLE+RF++ VR
Sbjct: 71  VQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFSRAVR 130

Query: 129 LCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVIWT 188
           LCGT+ +IV T+LYTGIVIYAPAL LNQVTG D+W ++++TG++CTFY  +GG+KAV+WT
Sbjct: 131 LCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWT 190

Query: 189 DVFQVGIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQRHTFWTIIIG 248
           DVFQV +M++GF  V+ + V++ GG   +L  A +  R+N  +FNP+P  R+TFWT ++G
Sbjct: 191 DVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTFVVG 250

Query: 249 GTFTWTSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGLALYSRYHDC 308
           GT  W S+YGVNQ+QVQRY++C++  QAKL+L IN VGL+ I++ +  CG+ ++  Y DC
Sbjct: 251 GTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFVFYTDC 310

Query: 309 DPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINALAAVTVEDL 368
           DP    ++SAPDQ MP LVLDI +D PG+PGLF+ACAYSGTLST S+SINA+AAVTVEDL
Sbjct: 311 DPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDL 370

Query: 369 IKPYFRSLSERSLSWISQGMSVVYGALCIGMAALASLM-GALLQAALSVFGMVGGPLMGL 427
           IKP  RSL+ R L  IS+G+S++YG+ C+ +AAL+SL+ G +LQ + +V G++ GPL+G 
Sbjct: 371 IKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGA 430

Query: 428 FALGILVPFANSIGALVGLMAGFAISLWVGIGAQIYPPLPERTLPLHLDIQGCNS-TYNE 486
           F LG+ +P  N+ G L GL AG A+SLWV +GA +YPP  +    L      C + + N 
Sbjct: 431 FILGMFLPACNTPGVLAGLGAGLALSLWVALGATLYPPSEQTMRVLPSSAARCVALSVNA 490

Query: 487 TNLMTTTEMPFTTS---VFQIYNVQRTPLMDNWYSLSYLYFSTVGTLVTLLVGILVSLST 543
           + L+    +P   S        +  R  L D++Y++SYLY+  +GTL T+L G L+S  T
Sbjct: 491 SGLLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTVLCGALISCLT 550

Query: 544 GGRKQN 549
           G  K++
Sbjct: 551 GPTKRS 556


>gi|10863879 solute carrier family 5 (sodium-dependent vitamin
           transporter), member 6 [Homo sapiens]
          Length = 635

 Score =  502 bits (1293), Expect = e-142
 Identities = 265/560 (47%), Positives = 360/560 (64%), Gaps = 21/560 (3%)

Query: 3   TPRGIGTFVVWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLT 62
           T  G+ TF + DYVVF  +LV+S AIG+Y+A  G G+ T  + LM  R+M  +PVALSL 
Sbjct: 17  TSVGMSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLL 76

Query: 63  ASFMSAVTVLGTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELR 122
           A+F SAV +LG PSE+YRFG  +      YF  ++I A +F+PVFY+L +TS YEYLELR
Sbjct: 77  ATFQSAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELR 136

Query: 123 FNKCVRLCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGL 182
           FNK VR+CGTV FI Q ++Y G+V+YAP+LALN VTGFDLW +V+A G+VCT Y  LGGL
Sbjct: 137 FNKTVRVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGL 196

Query: 183 KAVIWTDVFQVGIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQRHTF 242
           KAVIWTDVFQ  +M  G  +VII      GG+  +   A   GR++ +  +P+P  RHTF
Sbjct: 197 KAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVRHTF 256

Query: 243 WTIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGLALY 302
           WT+  GG F   S+YGVNQ+QVQRY+S ++   A LS Y         L      GL ++
Sbjct: 257 WTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCLIGLVMF 316

Query: 303 SRYHDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINALAA 362
           + Y +      +  +APDQ + Y V+D+L+  PGLPGLF+AC +SG+LST+SS+ N+LA 
Sbjct: 317 AYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNSLAT 376

Query: 363 VTVEDLIKPYFRSLSERSLSWISQGMSVVYGALCIGMAALASLMGALLQAALSVFGMVGG 422
           VT+EDLI+P+F   SE     +S+G++  YG LC+GMA ++S MG +LQAA+S+FGMVGG
Sbjct: 377 VTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYISSQMGPVLQAAISIFGMVGG 436

Query: 423 PLMGLFALGILVPFANSIGALVGLMAGFAISLWVGIGAQI------YPPLPERTLPLHLD 476
           PL+GLF LG+  P AN  GA+VGL+AG  ++ W+GIG+ +       PP P       L 
Sbjct: 437 PLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIGSIVTSMGFSMPPSPSNGSSFSLP 496

Query: 477 IQGCNSTYNETNLMTTTEMPFTTSVFQIYNVQRTPLMDNWYSLSYLYFSTVGTLVTLLVG 536
                   N T    TT MP TT         +   +  +YSLSYL++S   +   ++VG
Sbjct: 497 T-------NLTVATVTTLMPLTT-------FSKPTGLQRFYSLSYLWYSAHNSTTVIVVG 542

Query: 537 ILVSLSTGG-RKQNLDPRYI 555
           ++VSL TG  R ++L+P  I
Sbjct: 543 LIVSLLTGRMRGRSLNPATI 562


>gi|109659839 solute carrier family 5 (sodium/glucose
           cotransporter), member 10 isoform 1 [Homo sapiens]
          Length = 612

 Score =  107 bits (266), Expect = 4e-23
 Identities = 116/486 (23%), Positives = 209/486 (43%), Gaps = 50/486 (10%)

Query: 12  VWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSAVTV 71
           V D +V      ++ A+GI+ +     + T   + + GR MT  P+  SL AS   +   
Sbjct: 18  VADIIVITVYFALNVAVGIWSS-CRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLF 76

Query: 72  LGTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRFN-KCVRLC 130
           +G        G   + F +   +V++  A VF+P++    I +  EY++ R+  + +R+ 
Sbjct: 77  IGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRMY 136

Query: 131 GTVLFIVQTILYT-GIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVIWTD 189
            +VL ++ ++     + +YA AL ++   G++ + + + T  +   Y   GGL AVI+TD
Sbjct: 137 LSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTD 196

Query: 190 VFQVGIMVAGFASVIIQAVVMQGGIS-------------TILNDAYDGGRLNFWNFNPNP 236
             Q  IMV G   + I+A    GG               TI N      R +  +   +P
Sbjct: 197 ALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCHLPRTDAMHMFRDP 256

Query: 237 LQRHTFWT-IIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAK----LSLYINLVGLWAI- 290
                 WT +  G T   T  +  +Q  VQR +S +    AK    L+ Y+ ++ +  I 
Sbjct: 257 HTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLPMGLII 316

Query: 291 ----LTCSVFCGLALYSRYH----------------DCDPWTAKKVSAPDQLMPYLVLDI 330
               ++ ++F G  +Y   H                +C      +V   +   P LV+++
Sbjct: 317 MPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSNIAYPKLVMEL 376

Query: 331 LQDYPGLPGLFVACAYSGTLSTVSSSINALAAVTVEDLIKPYFRSLSERSLSWISQGMSV 390
           +    GL GL +A   +  +S+++S  N+ + +   D+ +       ER L  +  G  V
Sbjct: 377 MP--IGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLV--GRLV 432

Query: 391 VYGALCIGMAALASLM----GALLQAALSVFGMVGGPLMGLFALGILVPFANSIGALVGL 446
           +   + + +A +  L     G L     SV   +  P+  +F LG+    AN  GA  GL
Sbjct: 433 IVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGL 492

Query: 447 MAGFAI 452
           +AG  +
Sbjct: 493 IAGLVV 498


>gi|4507031 solute carrier family 5 (sodium/glucose cotransporter),
           member 1 [Homo sapiens]
          Length = 664

 Score =  104 bits (259), Expect = 3e-22
 Identities = 112/477 (23%), Positives = 198/477 (41%), Gaps = 43/477 (9%)

Query: 14  DYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSAVTVLG 73
           D  +     V+  A+G++  F+   + T   F + GR M   P+  SL AS + +   +G
Sbjct: 28  DISIIVIYFVVVMAVGLWAMFSTN-RGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVG 86

Query: 74  TPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRFNKCVRLCGTV 133
                   G     F +    +VV+   +F+P++ K G+ +  EYL  RF    +     
Sbjct: 87  LAGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGG--QRIQVY 144

Query: 134 LFIVQTILY----TGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVIWTD 189
           L ++  +LY        I++ A+ +N   G +L+ A+     +   Y   GGL AVI+TD
Sbjct: 145 LSLLSLLLYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYTD 204

Query: 190 VFQVGIMVAG-----------------FASVIIQAV--VMQGGISTILNDAYDGGRLNFW 230
             Q  IM+ G                 F    ++A+  ++  G +T     Y     +F 
Sbjct: 205 TLQTVIMLVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDGNTTFQEKCYTPRADSFH 264

Query: 231 NFNPNPLQRHTFWTIIIGGTFTWTSIYG-VNQSQVQRYISCKSRFQAK----LSLYINLV 285
            F  +PL     W   I G    T  Y   +Q  VQR +S K+    K    L  Y+ L+
Sbjct: 265 IFR-DPLTGDLPWPGFIFGMSILTLWYWCTDQVIVQRCLSAKNMSHVKGGCILCGYLKLM 323

Query: 286 GLWAILTCSVFCGLALYSRY------HDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPG 339
            ++ I+         LY+         +C+ +   KV   +   P LV++++ +  GL G
Sbjct: 324 PMF-IMVMPGMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPN--GLRG 380

Query: 340 LFVACAYSGTLSTVSSSINALAAVTVEDLIKPYFRSLSERSLSWISQGMSVVYGALCIGM 399
           L ++   +  +S+++S  N+ + +   D+     +  SE+ L    +   +V   + I  
Sbjct: 381 LMLSVMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKELMIAGRLFILVLIGISIAW 440

Query: 400 AAL--ASLMGALLQAALSVFGMVGGPLMGLFALGILVPFANSIGALVGLMAGFAISL 454
             +  ++  G L     S+   +G P+  +F L I     N  GA  GL+ G  I +
Sbjct: 441 VPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLILGLLIGI 497


>gi|109659836 solute carrier family 5 (sodium/glucose
           cotransporter), member 10 isoform 2 [Homo sapiens]
          Length = 596

 Score =  104 bits (259), Expect = 3e-22
 Identities = 114/471 (24%), Positives = 205/471 (43%), Gaps = 36/471 (7%)

Query: 12  VWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSAVTV 71
           V D +V      ++ A+GI+ +     + T   + + GR MT  P+  SL AS   +   
Sbjct: 18  VADIIVITVYFALNVAVGIWSS-CRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLF 76

Query: 72  LGTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRFN-KCVRLC 130
           +G        G   + F +   +V++  A VF+P++    I +  EY++ R+  + +R+ 
Sbjct: 77  IGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRMY 136

Query: 131 GTVLFIVQTILYT-GIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVIWTD 189
            +VL ++ ++     + +YA AL ++   G++ + + + T  +   Y   GGL AVI+TD
Sbjct: 137 LSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTD 196

Query: 190 VFQVGIMVAGFASVIIQAVVMQGGIS-------------TILNDAYDGGRLNFWNFNPNP 236
             Q  IMV G   + I+A    GG               TI N      R +  +   +P
Sbjct: 197 ALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCHLPRTDAMHMFRDP 256

Query: 237 LQRHTFWT-IIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAK----LSLYINLVGLWAIL 291
                 WT +  G T   T  +  +Q  VQR +S +    AK    L+ Y+ ++ +  I+
Sbjct: 257 HTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLPMGLII 316

Query: 292 TCSVFCGLALYSR------YHDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACA 345
              +    AL+          +C      +V   +   P LV++++    GL GL +A  
Sbjct: 317 MPGMI-SRALFPDDVGCVVPSECLRACGAEVGCSNIAYPKLVMELMP--IGLRGLMIAVM 373

Query: 346 YSGTLSTVSSSINALAAVTVEDLIKPYFRSLSERSLSWISQGMSVVYGALCIGMAALASL 405
            +  +S+++S  N+ + +   D+ +       ER L  +  G  V+   + + +A +  L
Sbjct: 374 LAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLV--GRLVIVALIGVSVAWIPVL 431

Query: 406 M----GALLQAALSVFGMVGGPLMGLFALGILVPFANSIGALVGLMAGFAI 452
                G L     SV   +  P+  +F LG+    AN  GA  GL+AG  +
Sbjct: 432 QDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGLIAGLVV 482


>gi|14140236 solute carrier family 5 (low affinity glucose
           cotransporter), member 4 [Homo sapiens]
          Length = 659

 Score = 99.8 bits (247), Expect = 7e-21
 Identities = 116/475 (24%), Positives = 193/475 (40%), Gaps = 39/475 (8%)

Query: 14  DYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSAVTVLG 73
           D  V     ++  A+G++ A     + T   F + GR M   P+  SL AS + +   +G
Sbjct: 28  DISVIVIYFLVVMAVGLW-AMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSNHYVG 86

Query: 74  TPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRF---NKCVRLC 130
                   G     F +T   +++I   +F+P++ K G+ +  EYL+ RF      V L 
Sbjct: 87  LAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQVYLS 146

Query: 131 GTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVIWTDV 190
              LFI   +L     I+A A+ +    G DL+ A+     +   Y T GGL +VI+TD 
Sbjct: 147 ILSLFIC-VVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIYTDT 205

Query: 191 FQVGIMVAG-----------------FASVIIQAV--VMQGGISTILNDAYDGGRLNFWN 231
            Q  IM+ G                 F    + A   V++G   TI    Y     +F  
Sbjct: 206 LQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTISASCYTPRADSFHI 265

Query: 232 FNPNPLQRHTFWTIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAK----LSLYINLVGL 287
           F         +  II G   T    +  NQ  VQR +  K     K    +  Y+ L+ +
Sbjct: 266 FRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIMCAYLKLLPM 325

Query: 288 WAILTCSVFCGLALYSRY------HDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLF 341
           + ++   +   + LY+         +C       V   +   P +VL+++    GL GL 
Sbjct: 326 FLMVMPGMISRI-LYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLELMPQ--GLRGLM 382

Query: 342 VACAYSGTLSTVSSSINALAAVTVEDLIKPYFRSLSERSLSWISQGMSVVYGALCIGMAA 401
           ++   +  +S+++S  N+ + +   DL     +  SE+ L    +   ++   + I    
Sbjct: 383 LSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGRIFVLLLTVVSIVWVP 442

Query: 402 L--ASLMGALLQAALSVFGMVGGPLMGLFALGILVPFANSIGALVGLMAGFAISL 454
           L   S  G L+    S+   +G P+  +F L I     N  GA  GLM G A+ L
Sbjct: 443 LVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWGLMVGLAMGL 497


>gi|17941285 solute carrier family 5 (sodium/glucose cotransporter),
           member 11 [Homo sapiens]
          Length = 675

 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 109/450 (24%), Positives = 190/450 (42%), Gaps = 43/450 (9%)

Query: 39  QQTSKDFLMGGRRMTAVPVALSLTASFMSAVTVLGTPSEVYRFGAIFSIFAFTYFFVVVI 98
           + T K + + G  M   PV  SL AS + +   +G        G   S +     F V++
Sbjct: 52  RDTVKGYFLAGGDMVWWPVGASLFASNVGSGHFIGLAGSGAATGISVSAYELNGLFSVLM 111

Query: 99  SAEVFLPVFYKLGITSTYEYLELRFNKCVRLCGTVLFIVQTILYTGIVI--------YAP 150
            A +FLP++    +T+  EYL  RF       G  + I+  +LY  I I        YA 
Sbjct: 112 LAWIFLPIYIAGQVTTMPEYLRKRFG------GIRIPIILAVLYLFIYIFTKISVDMYAG 165

Query: 151 ALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVIWTDVFQVGIMVAGFASVIIQAVVM 210
           A+ + Q    DL+ A+V    +   Y   GGL AVI+TD  Q  IM+ G  +++  +   
Sbjct: 166 AIFIQQSLHLDLYLAIVGLLAITAVYTVAGGLAAVIYTDALQTLIMLIGALTLMGYSFAA 225

Query: 211 QGGISTIL-------------NDAYDGGRLNFWNFNPNPLQRHTFWT-IIIGGTFTWTSI 256
            GG+  +              N +    R + ++   +PL     W  ++ G +      
Sbjct: 226 VGGMEGLKEKYFLALASNRSENSSCGLPREDAFHIFRDPLTSDLPWPGVLFGMSIPSLWY 285

Query: 257 YGVNQSQVQRYISCKSRFQAK----LSLYINLVGLWAILTCSVFCGLALYSRYHDCDPWT 312
           +  +Q  VQR ++ K+   AK    ++ Y+ ++ L+ ++   +   +    +    DP  
Sbjct: 286 WCTDQVIVQRTLAAKNLSHAKGGALMAAYLKVLPLFIMVFPGMVSRILFPDQVACADPEI 345

Query: 313 AKKV-----SAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINALAAVTVED 367
            +K+        D   P LVL++L    GL GL +A   +  +S+++S  N+ + +   D
Sbjct: 346 CQKICSNPSGCSDIAYPKLVLELLP--TGLRGLMMAVMVAALMSSLTSIFNSASTIFTMD 403

Query: 368 LIKPYFRSLSERSLSWISQG---MSVVYGALCIGMAALASLMGALLQAALSVFGMVGGPL 424
           L        SE+ L  + +    + V+   L I +   AS  G L     S+   +  P+
Sbjct: 404 LWNHLRPRASEKELMIVGRVFVLLLVLVSILWIPVVQ-ASQGGQLFIYIQSISSYLQPPV 462

Query: 425 MGLFALGILVPFANSIGALVGLMAGFAISL 454
             +F +G      N  GA  GL++G  + L
Sbjct: 463 AVVFIMGCFWKRTNEKGAFWGLISGLLLGL 492


>gi|4507033 solute carrier family 5 (sodium/glucose cotransporter),
           member 2 [Homo sapiens]
          Length = 672

 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 110/481 (22%), Positives = 204/481 (42%), Gaps = 48/481 (9%)

Query: 14  DYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSAVTVLG 73
           D +V A   ++   +G++ +     + T   + + GR M   PV  SL AS + +   +G
Sbjct: 25  DILVIAAYFLLVIGVGLW-SMCRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGSGHFVG 83

Query: 74  TPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRF-NKCVRLCGT 132
                   G   + F +   FVV++   +F PV+   G+ +  +YL  RF  + +RL  +
Sbjct: 84  LAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFGGRRIRLYLS 143

Query: 133 VLFIVQTIL-YTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVIWTDVF 191
           VL +   I     + +++ A+ + Q  G++++ +V+A   +   Y   GGL A+++TD  
Sbjct: 144 VLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMYTDTV 203

Query: 192 QVGIMVAGFASVIIQAVVMQGGISTILNDAYDG-------------GRLNFWNFNPNP-- 236
           Q  +++ G   ++  A    GG S +  D Y G             G ++ + + P P  
Sbjct: 204 QTFVILGGACILMGYAFHEVGGYSGLF-DKYLGAATSLTVSEDPAVGNISSFCYRPRPDS 262

Query: 237 --LQRHTF-----W-TIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAK----LSLYINL 284
             L RH       W  +++G T      +  +Q  VQR ++ KS    K    L  Y+ L
Sbjct: 263 YHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLTHIKAGCILCGYLKL 322

Query: 285 VGLWAILTCSVFCGLALYSRYHD---------CDPWTAKKVSAPDQLMPYLVLDILQDYP 335
             ++ +    V  G+     Y D         C      +V   +   P LV+ ++ +  
Sbjct: 323 TPMFLM----VMPGMISRILYPDEVACVVPEVCRRVCGTEVGCSNIAYPRLVVKLMPN-- 376

Query: 336 GLPGLFVACAYSGTLSTVSSSINALAAVTVEDLIKPYFRSLSERSLSWISQGMSVVYGAL 395
           GL GL +A   +  +S+++S  N+ + +   D+         +R L  + +   V    +
Sbjct: 377 GLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGRLWVVFIVVV 436

Query: 396 CIGMAAL--ASLMGALLQAALSVFGMVGGPLMGLFALGILVPFANSIGALVGLMAGFAIS 453
            +    +  A+  G L     +V   +  P+  +F L + VP  N  GA  GL+ G  + 
Sbjct: 437 SVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFWGLIGGLLMG 496

Query: 454 L 454
           L
Sbjct: 497 L 497


>gi|110835708 solute carrier family 5 (inositol transporters),
           member 3 [Homo sapiens]
          Length = 718

 Score = 93.6 bits (231), Expect = 5e-19
 Identities = 104/476 (21%), Positives = 192/476 (40%), Gaps = 41/476 (8%)

Query: 14  DYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSAVTVLG 73
           D  + A   ++   IG ++A     + T   + + GR MT V +  SL  S + +   +G
Sbjct: 9   DIAIVALYFILVMCIG-FFAMWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNIGSEHFIG 67

Query: 74  TPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRF--NKCVRLCG 131
                   G     + F    ++ +   VF+P++ + G+ +  EYL  RF  ++      
Sbjct: 68  LAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFA 127

Query: 132 TVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVIWTDVF 191
            +  I+       + +Y+ AL + +  G++L+ +V+    +       GGL AVI+TD  
Sbjct: 128 ALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTL 187

Query: 192 QVGIMVAGFASVIIQAVVMQGGIS-------------TILNDAYDGGRLNFWNFNP---- 234
           Q  +M+ G  +++I +++  GG               T +   Y+    N  N +P    
Sbjct: 188 QALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNVSPKKEA 247

Query: 235 -----NPLQRHTFWT-IIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAK----LSLYINL 284
                NP      W   I+G T      +  +Q  VQR ++ K+   AK    ++ ++ L
Sbjct: 248 LKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKL 307

Query: 285 VGLWAILTCSVFC------GLALYSRYHDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLP 338
           + ++ I+   +         +A  +  H C      +    +   P LV+ ++    GL 
Sbjct: 308 LPMFIIVVPGMISRILFTDDIACINPEH-CMLVCGSRAGCSNIAYPRLVMKLVP--VGLR 364

Query: 339 GLFVACAYSGTLSTVSSSINALAAVTVEDLIKPYFRSLSERSLSWISQGMSVVYGALCIG 398
           GL +A   +  +S + S  N+ + +   D+ K   +S S R L  + +        + I 
Sbjct: 365 GLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVISIA 424

Query: 399 MAALASLM--GALLQAALSVFGMVGGPLMGLFALGILVPFANSIGALVGLMAGFAI 452
              +   M  G +      V   +  P+  LF L I     N  GA  G MAGF +
Sbjct: 425 WVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVL 480


>gi|206597483 solute carrier family 5 (sodium/glucose
           cotransporter), member 9 isoform 2 [Homo sapiens]
          Length = 681

 Score = 90.9 bits (224), Expect = 3e-18
 Identities = 111/470 (23%), Positives = 201/470 (42%), Gaps = 32/470 (6%)

Query: 13  WDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSAVTVL 72
           +D  V     V   A+GI+ +     + T   + + GR M+  P+  SL +S + +   +
Sbjct: 36  YDISVVVIYFVFVIAVGIWSSIRAS-RGTIGGYFLAGRSMSWWPIGASLMSSNVGSGLFI 94

Query: 73  GTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRFN-KCVRLCG 131
           G        G     F +   ++++    VF+PV+   G+ +  +YL+ RF  + +++  
Sbjct: 95  GLAGTGAAGGLAVGGFEWNATWLLLALGWVFVPVYIAAGVVTMPQYLKKRFGGQRIQVYM 154

Query: 132 TVLFIVQTILYTGIV--IYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVIWTD 189
           +VL ++  I +T I   I++ AL +    G++L+ +     VV   Y   GGL AVI+TD
Sbjct: 155 SVLSLILYI-FTKISTDIFSGALFIQMALGWNLYLSTGILLVVTAVYTIAGGLMAVIYTD 213

Query: 190 VFQVGIMVAGFASVII---QAVVMQGGIS----------TILNDAYDGGRLNFWNFNPNP 236
             Q  IMV G   ++    Q V    G+           T+ N      R + ++   +P
Sbjct: 214 ALQTVIMVGGALVLMFLGFQDVGWYPGLEQRYRQAIPNVTVPNTTCHLPRPDAFHILRDP 273

Query: 237 LQRHTFWT-IIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAK----LSLYINLVGLWAIL 291
           +     W  +I G T   T  +  +Q  VQR +S KS   AK    L  Y+ ++ ++ I+
Sbjct: 274 VSGDIPWPGLIFGLTVLATWCWCTDQVIVQRSLSAKSLSHAKGGSVLGGYLKILPMFFIV 333

Query: 292 TCSVFCGLALYSRYHDCDPWTAKK-----VSAPDQLMPYLVLDILQDYPGLPGLFVACAY 346
              +             DP   ++     V   +   P LV+ ++    GL GL +A   
Sbjct: 334 MPGMISRALFPDEVGCVDPDVCQRICGARVGCSNIAYPKLVMALMP--VGLRGLMIAVIM 391

Query: 347 SGTLSTVSSSINALAAVTVEDLIKPYFRSLSERSLSWISQGMSVVYGALCIGMAAL--AS 404
           +  +S+++S  N+ + +   D+ + + R  +E+ L  + +   V    + I    +  +S
Sbjct: 392 AALMSSLTSIFNSSSTLFTIDVWQRFRRKSTEQELMVVGRVFVVFLVVISILWIPIIQSS 451

Query: 405 LMGALLQAALSVFGMVGGPLMGLFALGILVPFANSIGALVGLMAGFAISL 454
             G L     +V   +  P+  LF L I        GA  GL+ G  + L
Sbjct: 452 NSGQLFDYIQAVTSYLAPPITALFLLAIFCKRVTEPGAFWGLVFGLGVGL 501


>gi|206597487 solute carrier family 5 (sodium/glucose
           cotransporter), member 9 isoform 1 [Homo sapiens]
          Length = 706

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 94/381 (24%), Positives = 166/381 (43%), Gaps = 31/381 (8%)

Query: 102 VFLPVFYKLGITSTYEYLELRFN-KCVRLCGTVLFIVQTILYTGIV--IYAPALALNQVT 158
           VF+PV+   G+ +  +YL+ RF  + +++  +VL ++  I +T I   I++ AL +    
Sbjct: 149 VFVPVYIAAGVVTMPQYLKKRFGGQRIQVYMSVLSLILYI-FTKISTDIFSGALFIQMAL 207

Query: 159 GFDLWGAVVATGVVCTFYCTLGGLKAVIWTDVFQVGIMVAGFASVII---QAVVMQGGIS 215
           G++L+ +     VV   Y   GGL AVI+TD  Q  IMV G   ++    Q V    G+ 
Sbjct: 208 GWNLYLSTGILLVVTAVYTIAGGLMAVIYTDALQTVIMVGGALVLMFLGFQDVGWYPGLE 267

Query: 216 ----------TILNDAYDGGRLNFWNFNPNPLQRHTFWT-IIIGGTFTWTSIYGVNQSQV 264
                     T+ N      R + ++   +P+     W  +I G T   T  +  +Q  V
Sbjct: 268 QRYRQAIPNVTVPNTTCHLPRPDAFHILRDPVSGDIPWPGLIFGLTVLATWCWCTDQVIV 327

Query: 265 QRYISCKSRFQAK----LSLYINLVGLWAILTCSVFCGLALYSRYHDCDPWTAKK----- 315
           QR +S KS   AK    L  Y+ ++ ++ I+   +             DP   ++     
Sbjct: 328 QRSLSAKSLSHAKGGSVLGGYLKILPMFFIVMPGMISRALFPDEVGCVDPDVCQRICGAR 387

Query: 316 VSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINALAAVTVEDLIKPYFRS 375
           V   +   P LV+ ++    GL GL +A   +  +S+++S  N+ + +   D+ + + R 
Sbjct: 388 VGCSNIAYPKLVMALMP--VGLRGLMIAVIMAALMSSLTSIFNSSSTLFTIDVWQRFRRK 445

Query: 376 LSERSLSWISQGMSVVYGALCIGMAAL--ASLMGALLQAALSVFGMVGGPLMGLFALGIL 433
            +E+ L  + +   V    + I    +  +S  G L     +V   +  P+  LF L I 
Sbjct: 446 STEQELMVVGRVFVVFLVVISILWIPIIQSSNSGQLFDYIQAVTSYLAPPITALFLLAIF 505

Query: 434 VPFANSIGALVGLMAGFAISL 454
                  GA  GL+ G  + L
Sbjct: 506 CKRVTEPGAFWGLVFGLGVGL 526


>gi|11141885 solute carrier family 5 (choline transporter), member 7
           [Homo sapiens]
          Length = 580

 Score = 67.0 bits (162), Expect = 5e-11
 Identities = 94/453 (20%), Positives = 194/453 (42%), Gaps = 46/453 (10%)

Query: 28  IGIYYAF----AGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSAVTVLGTPSEVY--RF 81
           +GI+ A+    +G  ++ S+  ++GGR +  +    ++TA+++    + GT   VY   +
Sbjct: 21  VGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYVPGY 80

Query: 82  GAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRFNKCVRLCGTVLFI---VQ 138
           G  ++     Y   +++    F       G  +  +  +  + K +   G +LFI   + 
Sbjct: 81  GLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRM---GGLLFIPALMG 137

Query: 139 TILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVIWTDVFQ-----V 193
            + +   +  A    ++ +   D+  +V+ + ++ T Y  +GGL +V +TDV Q     V
Sbjct: 138 EMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGGLYSVAYTDVVQLFCIFV 197

Query: 194 GIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQRHTFWTIIIGGTFTW 253
           G+ ++   ++   AV   G   T ++  Y    L   + +       +F  +++GG   W
Sbjct: 198 GLWISVPFALSHPAVADIG--FTAVHAKYQKPWLGTVDSSEVYSWLDSFLLLMLGG-IPW 254

Query: 254 TSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGLALYS------RYHD 307
                  Q+  QR +S  S   A++  ++   G   +   ++  G    S       Y  
Sbjct: 255 -------QAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDWNQTAYGL 307

Query: 308 CDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINALAAVTVED 367
            DP T ++    D ++P ++  +   Y    GL    A    +S+  SSI + +++   +
Sbjct: 308 PDPKTTEEA---DMILPIVLQYLCPVYISFFGLGAVSA--AVMSSADSSILSASSMFARN 362

Query: 368 LIKPYFR-SLSERSLSWISQGMSVVYGALCIGMAALASLMGALLQAALSVFGMVGGP--L 424
           + +  FR + S++ + W+ +    V+GA    MA L   +  L   +  +  +V  P  L
Sbjct: 363 IYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQLL 422

Query: 425 MGLFALGILVPFANSIGALVGLMAGFAISLWVG 457
             LF  G      N+ GA+ G ++G  + +  G
Sbjct: 423 CVLFVKG-----TNTYGAVAGYVSGLFLRITGG 450


>gi|239751877 PREDICTED: hypothetical protein XP_002348035 [Homo
           sapiens]
          Length = 944

 Score = 33.9 bits (76), Expect = 0.45
 Identities = 19/42 (45%), Positives = 23/42 (54%)

Query: 393 GALCIGMAALASLMGALLQAALSVFGMVGGPLMGLFALGILV 434
           G    G+AALA+L+G L +    V    GG L GL ALG  V
Sbjct: 478 GGALEGLAALATLVGPLARVVPQVVAQPGGALEGLAALGTFV 519


>gi|207444687 solute carrier family 41, member 2 [Homo sapiens]
          Length = 573

 Score = 33.9 bits (76), Expect = 0.45
 Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 5/104 (4%)

Query: 357 INALAAVTVEDLIKPYFRSLSERSLSWISQGMSVVYGALCIGMAALAS-LMGALLQAALS 415
           I  LA   V+  +  +  +++   L WI +G   +  ++ +  +++A+  + +LLQ  + 
Sbjct: 238 IGNLALKQVQATVVGFLAAVAAIILGWIPEGKYYLDHSILLCSSSVATAFIASLLQGIIM 297

Query: 416 VFGMVGGPLMGLFALGILVPFANSIGALVGLMAGFAISLWVGIG 459
           V  +VG    G+    +  P A S G L+ L    AI  W+  G
Sbjct: 298 VGVIVGSKKTGINPDNVATPIAASFGDLITL----AILAWISQG 337


>gi|51702206 solute carrier family 41 member 1 [Homo sapiens]
          Length = 513

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 22/110 (20%), Positives = 51/110 (46%), Gaps = 5/110 (4%)

Query: 360 LAAVTVEDLIKPYFRSLSERSLSWISQG-MSVVYGALCIGMAALASLMGALLQAALSVFG 418
           +A + V+  +  +  S++     WI  G  S+ +  L    +   + + +L+   + +  
Sbjct: 180 MALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGV 239

Query: 419 MVGGPLMGLFALGILVPFANSIGALV--GLMAGFAISLWVGIG--AQIYP 464
           ++G   +G+    +  P A S+G L+   L++G +  L++ +     IYP
Sbjct: 240 IIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYLELNHWRYIYP 289


>gi|45580709 unc-93 homolog B1 [Homo sapiens]
          Length = 597

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 39/162 (24%), Positives = 67/162 (41%), Gaps = 19/162 (11%)

Query: 387 GMSVVYGALCIGMAALASLMGALLQAALSVFGMVGGPLMGLFALGILVPFANSIGALVGL 446
           G+++ YG   +G+  LA L+ A         G     L+GL  L +  P     GA V L
Sbjct: 360 GIALGYGVCSVGLERLAYLLVAYS------LGASAASLLGLLGLWLPRPVPLVAGAGVHL 413

Query: 447 MAGFAISLWVGIGAQIYPPLPERTLPLHL--DIQGCNSTYNETNLMTTTEMPFTTS---- 500
           +  F +  W  +     P + + +  L++   + G  S  N+T L T   + +       
Sbjct: 414 LLTFILFFWAPV-----PRVLQHSWILYVAAALWGVGSALNKTGLSTLLGILYEDKERQD 468

Query: 501 -VFQIYNVQRTPLMDNWYSLSYLYF-STVGTLVTLLVGILVS 540
            +F IY+  +   +   Y  S L+  + +  L+  LV   VS
Sbjct: 469 FIFTIYHWWQAVAIFTVYLGSSLHMKAKLAVLLVTLVAAAVS 510


>gi|4885441 solute carrier family 17 (sodium phosphate), member 4
           [Homo sapiens]
          Length = 497

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 48/187 (25%), Positives = 73/187 (39%), Gaps = 14/187 (7%)

Query: 270 CKSRFQAKLSLYINLVGLWAILTCSVFCGLALYSRYHDCDPWTAKKVSAPDQLMPYLVLD 329
           C   +   +   I  + LWAIL  S FC    Y  ++    +T   +S+  Q        
Sbjct: 277 CSPGWSLPIRAMIKSLPLWAILV-SYFCE---YWLFYTIMAYTPTYISSVLQAN-LRDSG 331

Query: 330 ILQDYPGLPGLFVACAYSGTLSTVSSSINALAAVTVEDL---IKPYFRSLSERSLSWISQ 386
           IL   P + G  +     G L+    S   L  +T+  L   I   F S+   SL W+  
Sbjct: 332 ILSALPFVVGC-ICIILGGLLADFLLSRKILRLITIRKLFTAIGVLFPSVILVSLPWVRS 390

Query: 387 GMSVVYGALCIGMAALASLMGALLQAALSVFGMVGGPLMGLFALGILVPFANSIGALVGL 446
             S+    L      L+S + +  ++   V  +   P    F  G+L  FA+  GA+   
Sbjct: 391 SHSMTMTFL-----VLSSAISSFCESGALVNFLDIAPRYTGFLKGLLQVFAHIAGAISPT 445

Query: 447 MAGFAIS 453
            AGF IS
Sbjct: 446 AAGFFIS 452


>gi|25014088 solute carrier family 34 (sodium phosphate), member 3
           [Homo sapiens]
          Length = 599

 Score = 30.8 bits (68), Expect = 3.8
 Identities = 22/53 (41%), Positives = 32/53 (60%), Gaps = 8/53 (15%)

Query: 383 WISQGMSVVYGALCIGMAALA-SLMGALLQAALSVFGMVGGPLMGLFALGILV 434
           W++ G+ ++ G L + +AA   SL G ++ AA      VGGPL+GL  L ILV
Sbjct: 486 WVA-GVYLLLGFLLLPLAAFGLSLAGGMVLAA------VGGPLVGLVLLVILV 531


>gi|47933348 zinc finger, DHHC domain containing 13 isoform 2 [Homo
           sapiens]
          Length = 492

 Score = 30.4 bits (67), Expect = 5.0
 Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 11/58 (18%)

Query: 45  FLMGGRRMTAVPVALSLTASFMSAVT--------VLGTPSEVYRFGAIFSIFAFTYFF 94
           FL+G + +  +P A  L++ F   +T        + G P   + F  IFSI AF YFF
Sbjct: 207 FLVGYKNLVYLPTAFLLSSVFWIFMTWFILFFPDLAGAP---FYFSFIFSIVAFLYFF 261


>gi|47933346 zinc finger, DHHC domain containing 13 isoform 1 [Homo
           sapiens]
          Length = 622

 Score = 30.4 bits (67), Expect = 5.0
 Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 11/58 (18%)

Query: 45  FLMGGRRMTAVPVALSLTASFMSAVT--------VLGTPSEVYRFGAIFSIFAFTYFF 94
           FL+G + +  +P A  L++ F   +T        + G P   + F  IFSI AF YFF
Sbjct: 337 FLVGYKNLVYLPTAFLLSSVFWIFMTWFILFFPDLAGAP---FYFSFIFSIVAFLYFF 391


>gi|239508735 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 233

 Score = 30.0 bits (66), Expect = 6.5
 Identities = 17/74 (22%), Positives = 32/74 (43%), Gaps = 9/74 (12%)

Query: 84  IFSIFAFTYFFVVVISAEVFLPVF---------YKLGITSTYEYLELRFNKCVRLCGTVL 134
           ++ I+ +TY + V I   + + V+         Y       Y Y+ +  + CV +C  + 
Sbjct: 44  MYGIYVYTYIYCVYICVYIHIYVYIYIYVCIYVYTYIYVCIYVYICVYIHICVYICVYIH 103

Query: 135 FIVQTILYTGIVIY 148
             V   +YT I +Y
Sbjct: 104 ICVYICVYTHICVY 117


>gi|48717231 olfactory receptor, family 9, subfamily A, member 4
           [Homo sapiens]
          Length = 314

 Score = 29.6 bits (65), Expect = 8.5
 Identities = 28/106 (26%), Positives = 42/106 (39%), Gaps = 10/106 (9%)

Query: 71  VLGTPSEVYRFGAIFSIFAFTYF----------FVVVISAEVFLPVFYKLGITSTYEYLE 120
           +LG P        +F+IF F Y            +V +   +  P+++ LG  S  E L 
Sbjct: 13  LLGFPGSEELHHILFAIFFFFYLVTLMGNTVIIMIVCVDKRLQSPMYFFLGHLSALEILV 72

Query: 121 LRFNKCVRLCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAV 166
                 V L G +L  +QTI  +  V+          T F L GA+
Sbjct: 73  TTIIVPVMLWGLLLPGMQTIYLSACVVQLFLYLAVGTTEFALLGAM 118


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.140    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,560,434
Number of Sequences: 37866
Number of extensions: 903714
Number of successful extensions: 2414
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2365
Number of HSP's gapped (non-prelim): 36
length of query: 610
length of database: 18,247,518
effective HSP length: 108
effective length of query: 502
effective length of database: 14,157,990
effective search space: 7107310980
effective search space used: 7107310980
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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