Guide to the Human Genome
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Search of human proteins with 164419739

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|164419739 glutamate receptor, ionotrophic, AMPA 4 isoform 3
precursor [Homo sapiens]
         (433 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116284390 glutamate receptor, ionotrophic, AMPA 4 isoform 3 p...   877   0.0  
gi|164419739 glutamate receptor, ionotrophic, AMPA 4 isoform 3 p...   877   0.0  
gi|164419736 glutamate receptor, ionotrophic, AMPA 4 isoform 2 p...   857   0.0  
gi|164419734 glutamate receptor, ionotrophic, AMPA 4 isoform 1 p...   857   0.0  
gi|163659858 glutamate receptor, ionotrophic, AMPA 3 isoform 2 p...   546   e-155
gi|163659856 glutamate receptor, ionotrophic, AMPA 3 isoform 1 p...   546   e-155
gi|134304848 glutamate receptor, ionotropic, AMPA 2 isoform 2 pr...   514   e-146
gi|74275354 glutamate receptor, ionotropic, AMPA 2 isoform 1 pre...   514   e-146
gi|134304851 glutamate receptor, ionotropic, AMPA 2 isoform 3 [H...   477   e-135
gi|167001484 glutamate receptor, ionotropic, AMPA 1 isoform 2 [H...   454   e-128
gi|167001419 glutamate receptor, ionotropic, AMPA 1 isoform 1 [H...   454   e-128
gi|28605145 glutamate receptor, ionotropic, kainate 3 precursor ...   151   1e-36
gi|28416444 glutamate receptor, ionotropic, kainate 1 isoform 2 ...   145   7e-35
gi|4504117 glutamate receptor, ionotropic, kainate 1 isoform 1 p...   136   4e-32
gi|11386137 glutamate receptor, ionotropic, kainate 2 isoform 1 ...   135   9e-32
gi|28559003 glutamate receptor, ionotropic, kainate 2 isoform 2 ...   135   9e-32
gi|29029597 glutamate receptor KA2 precursor [Homo sapiens]            86   5e-17
gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens]    85   1e-16
gi|29029595 glutamate receptor KA1 precursor [Homo sapiens]            76   5e-14
gi|55770852 glutamate receptor, ionotropic, delta 1 precursor [H...    69   8e-12
gi|167003331 N-methyl-D-aspartate receptor subunit 2B precursor ...    36   0.078
gi|112789566 taste receptor, type 1, member 2 [Homo sapiens]           29   7.3  
gi|87116668 hypothetical protein LOC9870 [Homo sapiens]                29   7.3  

>gi|116284390 glutamate receptor, ionotrophic, AMPA 4 isoform 3
           precursor [Homo sapiens]
          Length = 433

 Score =  877 bits (2266), Expect = 0.0
 Identities = 433/433 (100%), Positives = 433/433 (100%)

Query: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
           MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA
Sbjct: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60

Query: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
           PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP
Sbjct: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120

Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
           SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180

Query: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
           VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA
Sbjct: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240

Query: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
           NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL
Sbjct: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300

Query: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
           TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN
Sbjct: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360

Query: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
           VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT
Sbjct: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420

Query: 421 TIMPLMKNPILRN 433
           TIMPLMKNPILRN
Sbjct: 421 TIMPLMKNPILRN 433


>gi|164419739 glutamate receptor, ionotrophic, AMPA 4 isoform 3
           precursor [Homo sapiens]
          Length = 433

 Score =  877 bits (2266), Expect = 0.0
 Identities = 433/433 (100%), Positives = 433/433 (100%)

Query: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
           MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA
Sbjct: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60

Query: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
           PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP
Sbjct: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120

Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
           SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180

Query: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
           VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA
Sbjct: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240

Query: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
           NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL
Sbjct: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300

Query: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
           TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN
Sbjct: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360

Query: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
           VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT
Sbjct: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420

Query: 421 TIMPLMKNPILRN 433
           TIMPLMKNPILRN
Sbjct: 421 TIMPLMKNPILRN 433


>gi|164419736 glutamate receptor, ionotrophic, AMPA 4 isoform 2
           precursor [Homo sapiens]
          Length = 884

 Score =  857 bits (2213), Expect = 0.0
 Identities = 423/423 (100%), Positives = 423/423 (100%)

Query: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
           MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA
Sbjct: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60

Query: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
           PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP
Sbjct: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120

Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
           SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180

Query: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
           VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA
Sbjct: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240

Query: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
           NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL
Sbjct: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300

Query: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
           TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN
Sbjct: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360

Query: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
           VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT
Sbjct: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420

Query: 421 TIM 423
           TIM
Sbjct: 421 TIM 423


>gi|164419734 glutamate receptor, ionotrophic, AMPA 4 isoform 1
           precursor [Homo sapiens]
          Length = 902

 Score =  857 bits (2213), Expect = 0.0
 Identities = 423/423 (100%), Positives = 423/423 (100%)

Query: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
           MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA
Sbjct: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60

Query: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
           PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP
Sbjct: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120

Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
           SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180

Query: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
           VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA
Sbjct: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240

Query: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
           NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL
Sbjct: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300

Query: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
           TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN
Sbjct: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360

Query: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
           VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT
Sbjct: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420

Query: 421 TIM 423
           TIM
Sbjct: 421 TIM 423


>gi|163659858 glutamate receptor, ionotrophic, AMPA 3 isoform 2
           precursor [Homo sapiens]
          Length = 894

 Score =  546 bits (1407), Expect = e-155
 Identities = 253/422 (59%), Positives = 341/422 (80%), Gaps = 3/422 (0%)

Query: 4   ISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFN 63
           + R +  L  G  G + G FP+++ IGGLF+RNT QE++AFR A+ L+NT+ N +E PF+
Sbjct: 11  VLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFH 70

Query: 64  LVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFP 123
           L  HVD+++++NSF+VTNAFCSQ+SRGV+AIFG YD+ S++TLTSFC ALH S +TPSFP
Sbjct: 71  LNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFP 130

Query: 124 TEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSA 183
           T+ + QFV+Q+RP+L+GA+LSLL HY+W  FV+LYDT+RG+SILQAIME A QN W V+A
Sbjct: 131 TDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTA 190

Query: 184 ICVENFNDV-SYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANL 242
             V N  DV  +R+++EE+DRRQEK+++IDCE+ER+  ILEQ+V +GKH +GYHY++ANL
Sbjct: 191 RSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANL 250

Query: 243 GFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-KYTSALT 301
           GF DI LER +HGGAN+TGFQ+V+   PMV + + RW +LD+RE+P ++  P KYTSALT
Sbjct: 251 GFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALT 310

Query: 302 YDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNV 361
           +D +LV+AE FR LRRQ++D+SRRG+AGDCLANPA PW QGID+ER LK V++QG+TGN+
Sbjct: 311 HDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNI 370

Query: 362 QFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTT 421
           QFD YGRR NYT+DV+E+K +G RK GYWN+ ++ V   D   + ND+A+ ENRT+VVTT
Sbjct: 371 QFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSD-QQISNDSASSENRTIVVTT 429

Query: 422 IM 423
           I+
Sbjct: 430 IL 431


>gi|163659856 glutamate receptor, ionotrophic, AMPA 3 isoform 1
           precursor [Homo sapiens]
          Length = 894

 Score =  546 bits (1407), Expect = e-155
 Identities = 253/422 (59%), Positives = 341/422 (80%), Gaps = 3/422 (0%)

Query: 4   ISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFN 63
           + R +  L  G  G + G FP+++ IGGLF+RNT QE++AFR A+ L+NT+ N +E PF+
Sbjct: 11  VLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFH 70

Query: 64  LVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFP 123
           L  HVD+++++NSF+VTNAFCSQ+SRGV+AIFG YD+ S++TLTSFC ALH S +TPSFP
Sbjct: 71  LNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFP 130

Query: 124 TEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSA 183
           T+ + QFV+Q+RP+L+GA+LSLL HY+W  FV+LYDT+RG+SILQAIME A QN W V+A
Sbjct: 131 TDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTA 190

Query: 184 ICVENFNDV-SYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANL 242
             V N  DV  +R+++EE+DRRQEK+++IDCE+ER+  ILEQ+V +GKH +GYHY++ANL
Sbjct: 191 RSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANL 250

Query: 243 GFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-KYTSALT 301
           GF DI LER +HGGAN+TGFQ+V+   PMV + + RW +LD+RE+P ++  P KYTSALT
Sbjct: 251 GFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALT 310

Query: 302 YDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNV 361
           +D +LV+AE FR LRRQ++D+SRRG+AGDCLANPA PW QGID+ER LK V++QG+TGN+
Sbjct: 311 HDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNI 370

Query: 362 QFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTT 421
           QFD YGRR NYT+DV+E+K +G RK GYWN+ ++ V   D   + ND+A+ ENRT+VVTT
Sbjct: 371 QFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSD-QQISNDSASSENRTIVVTT 429

Query: 422 IM 423
           I+
Sbjct: 430 IL 431


>gi|134304848 glutamate receptor, ionotropic, AMPA 2 isoform 2
           precursor [Homo sapiens]
          Length = 883

 Score =  514 bits (1325), Expect = e-146
 Identities = 239/428 (55%), Positives = 330/428 (77%), Gaps = 11/428 (2%)

Query: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
           M+ I    VLL    WGL  G   +S+QIGGLF R  DQEY+AFR+ +   +TS      
Sbjct: 1   MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE----- 55

Query: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
            F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC  LH+S ITP
Sbjct: 56  -FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITP 114

Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
           SFPT+G   FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A +  W 
Sbjct: 115 SFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174

Query: 181 VSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYH 236
           V+AI V N N    D  YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVKGYH
Sbjct: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234

Query: 237 YIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-K 295
           YIIANLGF D  L +   GGANV+GFQ+VD++  +V K ++RW  L+++EYPG+ T   K
Sbjct: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK 294

Query: 296 YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQ 355
           YTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV+++
Sbjct: 295 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE 354

Query: 356 GLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENR 415
           GL+GN++FD  G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+       GNDT+ +EN+
Sbjct: 355 GLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENK 414

Query: 416 TVVVTTIM 423
           TVVVTTI+
Sbjct: 415 TVVVTTIL 422


>gi|74275354 glutamate receptor, ionotropic, AMPA 2 isoform 1
           precursor [Homo sapiens]
          Length = 883

 Score =  514 bits (1325), Expect = e-146
 Identities = 239/428 (55%), Positives = 330/428 (77%), Gaps = 11/428 (2%)

Query: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
           M+ I    VLL    WGL  G   +S+QIGGLF R  DQEY+AFR+ +   +TS      
Sbjct: 1   MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE----- 55

Query: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
            F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC  LH+S ITP
Sbjct: 56  -FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITP 114

Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
           SFPT+G   FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A +  W 
Sbjct: 115 SFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174

Query: 181 VSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYH 236
           V+AI V N N    D  YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVKGYH
Sbjct: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234

Query: 237 YIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-K 295
           YIIANLGF D  L +   GGANV+GFQ+VD++  +V K ++RW  L+++EYPG+ T   K
Sbjct: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK 294

Query: 296 YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQ 355
           YTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV+++
Sbjct: 295 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE 354

Query: 356 GLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENR 415
           GL+GN++FD  G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+       GNDT+ +EN+
Sbjct: 355 GLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENK 414

Query: 416 TVVVTTIM 423
           TVVVTTI+
Sbjct: 415 TVVVTTIL 422


>gi|134304851 glutamate receptor, ionotropic, AMPA 2 isoform 3 [Homo
           sapiens]
          Length = 836

 Score =  477 bits (1228), Expect = e-135
 Identities = 214/371 (57%), Positives = 299/371 (80%), Gaps = 5/371 (1%)

Query: 58  SEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISL 117
           S + F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC  LH+S 
Sbjct: 5   STSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSF 64

Query: 118 ITPSFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQN 177
           ITPSFPT+G   FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A + 
Sbjct: 65  ITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEK 124

Query: 178 GWHVSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVK 233
            W V+AI V N N    D  YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVK
Sbjct: 125 KWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVK 184

Query: 234 GYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETP 293
           GYHYIIANLGF D  L +   GGANV+GFQ+VD++  +V K ++RW  L+++EYPG+ T 
Sbjct: 185 GYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTT 244

Query: 294 P-KYTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQV 352
             KYTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV
Sbjct: 245 TIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQV 304

Query: 353 RIQGLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAI 412
           +++GL+GN++FD  G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+       GNDT+ +
Sbjct: 305 QVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGL 364

Query: 413 ENRTVVVTTIM 423
           EN+TVVVTTI+
Sbjct: 365 ENKTVVVTTIL 375


>gi|167001484 glutamate receptor, ionotropic, AMPA 1 isoform 2 [Homo
           sapiens]
          Length = 906

 Score =  454 bits (1167), Expect = e-128
 Identities = 218/413 (52%), Positives = 296/413 (71%), Gaps = 9/413 (2%)

Query: 13  SGFWGLAMGA-FPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNI 71
           +GF G  +GA FP+++QIGGLF     QE+ AFR A+       +    P  L+P +D +
Sbjct: 10  TGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFAL-------SQLTEPPKLLPQIDIV 62

Query: 72  ETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQFV 131
             ++SF +T  FCSQ+S+GV+AIFG Y++R+V+ LTSFC ALH+  ITPSFP +  +QFV
Sbjct: 63  NISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFV 122

Query: 132 LQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFND 191
           LQLRP L+ AL+S++DHY+W  FV++YD DRG S+LQ +++ A +  W V+A+ +    +
Sbjct: 123 LQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTE 182

Query: 192 VSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLER 251
             YR L ++L++++E+  V+DCE ERL  IL QI+ + K+  GYHYI+ANLGF DI L +
Sbjct: 183 EGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNK 242

Query: 252 FIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSE-TPPKYTSALTYDGVLVMAE 310
           F   GANVTGFQLV++   +  K+M +WK  D R++   +   PKYTSALTYDGV VMAE
Sbjct: 243 FKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAE 302

Query: 311 TFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRV 370
            F+SLRRQ+IDISRRGNAGDCLANPA PWGQGID++R L+QVR +GLTGNVQF+  GRR 
Sbjct: 303 AFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRT 362

Query: 371 NYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIM 423
           NYT+ V E+K  G RK+GYWN+ DK V        G D ++++NRT +VTTI+
Sbjct: 363 NYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTIL 415


>gi|167001419 glutamate receptor, ionotropic, AMPA 1 isoform 1 [Homo
           sapiens]
          Length = 906

 Score =  454 bits (1167), Expect = e-128
 Identities = 218/413 (52%), Positives = 296/413 (71%), Gaps = 9/413 (2%)

Query: 13  SGFWGLAMGA-FPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNI 71
           +GF G  +GA FP+++QIGGLF     QE+ AFR A+       +    P  L+P +D +
Sbjct: 10  TGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFAL-------SQLTEPPKLLPQIDIV 62

Query: 72  ETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQFV 131
             ++SF +T  FCSQ+S+GV+AIFG Y++R+V+ LTSFC ALH+  ITPSFP +  +QFV
Sbjct: 63  NISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFV 122

Query: 132 LQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFND 191
           LQLRP L+ AL+S++DHY+W  FV++YD DRG S+LQ +++ A +  W V+A+ +    +
Sbjct: 123 LQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTE 182

Query: 192 VSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLER 251
             YR L ++L++++E+  V+DCE ERL  IL QI+ + K+  GYHYI+ANLGF DI L +
Sbjct: 183 EGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNK 242

Query: 252 FIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSE-TPPKYTSALTYDGVLVMAE 310
           F   GANVTGFQLV++   +  K+M +WK  D R++   +   PKYTSALTYDGV VMAE
Sbjct: 243 FKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAE 302

Query: 311 TFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRV 370
            F+SLRRQ+IDISRRGNAGDCLANPA PWGQGID++R L+QVR +GLTGNVQF+  GRR 
Sbjct: 303 AFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRT 362

Query: 371 NYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIM 423
           NYT+ V E+K  G RK+GYWN+ DK V        G D ++++NRT +VTTI+
Sbjct: 363 NYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTIL 415


>gi|28605145 glutamate receptor, ionotropic, kainate 3 precursor
           [Homo sapiens]
          Length = 919

 Score =  151 bits (381), Expect = 1e-36
 Identities = 117/438 (26%), Positives = 201/438 (45%), Gaps = 38/438 (8%)

Query: 10  LLFSGFWGLAMGAFPSSVQIGGLF---------IRNTDQEYTAFRLAIFLHNTS--PNAS 58
           LL   FW       P  ++IGG+F         + N ++    F   I   N +  PN +
Sbjct: 19  LLVCAFWIPDSRGMPHVIRIGGIFEYADGPNAQVMNAEEHAFRFSANIINRNRTLLPNTT 78

Query: 59  EAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSAL---HI 115
                L   +  I   +SF  T   C Q + GV AIFG       + + S C+AL   HI
Sbjct: 79  -----LTYDIQRIHFHDSFEATKKACDQLALGVVAIFGPSQGSCTNAVQSICNALEVPHI 133

Query: 116 SLITPSFPTEGESQFVLQLRP---SLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIME 172
            L     P + +  F + L P   SL  A+L L+ + +W     +YD   G   LQ ++ 
Sbjct: 134 QLRWKHHPLDNKDTFYVNLYPDYASLSHAILDLVQYLKWRSATVVYDDSTGLIRLQELIM 193

Query: 173 KAGQNGWHVSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHV 232
              +    +    +   +D S R LL+E+ R +E + + DC       IL+Q +++G   
Sbjct: 194 APSRYNIRLKIRQLPIDSDDS-RPLLKEMKRGREFRIIFDCSHTMAAQILKQAMAMGMMT 252

Query: 233 KGYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSET 292
           + YH+I   L    + LE + + G N+TGF++++ + P V  ++++W     +  P SE+
Sbjct: 253 EYYHFIFTTLDLYALDLEPYRYSGVNLTGFRILNVDNPHVSAIVEKWSMERLQAAPRSES 312

Query: 293 -----PPKYTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMER 347
                     +AL YD V +++  ++   +  +      N+  C  + A  W  G     
Sbjct: 313 GLLDGVMMTDAALLYDAVHIVSVCYQRAPQMTV------NSLQCHRHKA--WRFGGRFMN 364

Query: 348 TLKQVRIQGLTGNVQFDH-YGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLG 406
            +K+ + +GLTG + F+   G R ++ +D+  LK  G  KVG W+  D L + +     G
Sbjct: 365 FIKEAQWEGLTGRIVFNKTSGLRTDFDLDIISLKEDGLEKVGVWSPADGLNITEVAKGRG 424

Query: 407 -NDTAAIENRTVVVTTIM 423
            N T ++ NR+++VTT++
Sbjct: 425 PNVTDSLTNRSLIVTTVL 442


>gi|28416444 glutamate receptor, ionotropic, kainate 1 isoform 2
           precursor [Homo sapiens]
          Length = 905

 Score =  145 bits (366), Expect = 7e-35
 Identities = 110/416 (26%), Positives = 190/416 (45%), Gaps = 25/416 (6%)

Query: 24  PSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPF---NLVPHVDNIETANSFAVT 80
           P  ++IGG+F    ++      LA     TS N +        L   +  I   +SF  +
Sbjct: 34  PQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEAS 93

Query: 81  NAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFP---TEGESQFVLQLRP- 136
              C Q + GV A+FG     SV  + S C+AL +  I   +     + +  F + L P 
Sbjct: 94  RRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPD 153

Query: 137 --SLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFNDVSY 194
             ++  A+L L+ +Y W     +Y+   G   LQ +++   +    +    + + N  + 
Sbjct: 154 YAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDA- 212

Query: 195 RQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIH 254
           + LL+E+ + +E   + DC  E    IL+QI+ +G   + YHY    L    + LE + +
Sbjct: 213 KPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRY 272

Query: 255 GGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSET-----PPKYTSALTYDGVLVMA 309
            G N+TGF+L++ + P V  ++++W     +  P  ET          +AL YD V ++A
Sbjct: 273 SGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVA 332

Query: 310 ETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDH-YGR 368
               S R  ++ +S          +   PW  G      +K+ R  GLTG++ F+   G 
Sbjct: 333 --IASHRASQLTVS------SLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGL 384

Query: 369 RVNYTMDVFELKSTGPRKVGYWNDMDKLVLI-QDVPTLGNDTAAIENRTVVVTTIM 423
           R ++ +D+  LK  G  K+G WN    L +   +     N T ++ NRT++VTTI+
Sbjct: 385 RKDFDLDIISLKEEGTEKIGIWNSNSGLNMTDSNKDKSSNITDSLANRTLIVTTIL 440


>gi|4504117 glutamate receptor, ionotropic, kainate 1 isoform 1
           precursor [Homo sapiens]
          Length = 918

 Score =  136 bits (342), Expect = 4e-32
 Identities = 110/431 (25%), Positives = 191/431 (44%), Gaps = 40/431 (9%)

Query: 24  PSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPF---NLVPHVDNIETANSFAVT 80
           P  ++IGG+F    ++      LA     TS N +        L   +  I   +SF  +
Sbjct: 34  PQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEAS 93

Query: 81  NAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFP---TEGESQFVLQLRP- 136
              C Q + GV A+FG     SV  + S C+AL +  I   +     + +  F + L P 
Sbjct: 94  RRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPD 153

Query: 137 --SLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFNDVSY 194
             ++  A+L L+ +Y W     +Y+   G   LQ +++   +    +    + + N  + 
Sbjct: 154 YAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDA- 212

Query: 195 RQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIH 254
           + LL+E+ + +E   + DC  E    IL+QI+ +G   + YHY    L    + LE + +
Sbjct: 213 KPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRY 272

Query: 255 GGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSET-----PPKYTSALTYDGVLVMA 309
            G N+TGF+L++ + P V  ++++W     +  P  ET          +AL YD V ++A
Sbjct: 273 SGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVA 332

Query: 310 ETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDH-YGR 368
               S R  ++ +S          +   PW  G      +K+ R  GLTG++ F+   G 
Sbjct: 333 --IASHRASQLTVS------SLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGL 384

Query: 369 RVNYTMDVFELKSTGP---------------RKVGYWNDMDKLVLI-QDVPTLGNDTAAI 412
           R ++ +D+  LK  G                +K+G WN    L +   +     N T ++
Sbjct: 385 RKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTDSNKDKSSNITDSL 444

Query: 413 ENRTVVVTTIM 423
            NRT++VTTI+
Sbjct: 445 ANRTLIVTTIL 455


>gi|11386137 glutamate receptor, ionotropic, kainate 2 isoform 1
           precursor [Homo sapiens]
          Length = 908

 Score =  135 bits (339), Expect = 9e-32
 Identities = 115/443 (25%), Positives = 194/443 (43%), Gaps = 37/443 (8%)

Query: 3   IISRQIVLLFSGFW-GLAMGAFPSSVQIGGLF----IRNTDQEYTAFRLAIFLHNTS--- 54
           +  R + LL    W G + G     ++ GG+F          E  AFR A+   N +   
Sbjct: 12  VFRRTVKLLLCLLWIGYSQGT-THVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTL 70

Query: 55  -PNASEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSAL 113
            PN +     L      I   +SF  +   C Q S GV AIFG     S + + S C+AL
Sbjct: 71  LPNTT-----LTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNAL 125

Query: 114 ---HISLITPSFPTEGESQFVLQLRP---SLRGALLSLLDHYEWNCFVFLYDTDRGYSIL 167
              HI        ++ +  F + L P   SL  A+L L+  ++W     +YD   G   L
Sbjct: 126 GVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRL 185

Query: 168 QAIMEKAGQNGWHVSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVS 227
           Q +++   +    +  I     +    + LL+E+ R +E   + DC  E    IL+Q ++
Sbjct: 186 QELIKAPSRYNLRLK-IRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALA 244

Query: 228 VGKHVKGYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRW--KKLDQR 285
           +G   + YHYI   L    + +E + + G N+TGF++++     V  ++++W  ++L   
Sbjct: 245 MGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMERLQAP 304

Query: 286 EYPGSETPPKY---TSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQG 342
             P S     +    +AL YD V V++   +   +  +             N   PW  G
Sbjct: 305 PKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTV--------SSLQCNRHKPWRFG 356

Query: 343 IDMERTLKQVRIQGLTGNVQFDH-YGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQD 401
                 +K+   +GLTG + F+   G R ++ +DV  LK  G  K+G W+    L + + 
Sbjct: 357 TRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTES 416

Query: 402 VP-TLGNDTAAIENRTVVVTTIM 423
                 N T ++ NR+++VTTI+
Sbjct: 417 QKGKPANITDSLSNRSLIVTTIL 439


>gi|28559003 glutamate receptor, ionotropic, kainate 2 isoform 2
           precursor [Homo sapiens]
          Length = 869

 Score =  135 bits (339), Expect = 9e-32
 Identities = 115/443 (25%), Positives = 194/443 (43%), Gaps = 37/443 (8%)

Query: 3   IISRQIVLLFSGFW-GLAMGAFPSSVQIGGLF----IRNTDQEYTAFRLAIFLHNTS--- 54
           +  R + LL    W G + G     ++ GG+F          E  AFR A+   N +   
Sbjct: 12  VFRRTVKLLLCLLWIGYSQGT-THVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTL 70

Query: 55  -PNASEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSAL 113
            PN +     L      I   +SF  +   C Q S GV AIFG     S + + S C+AL
Sbjct: 71  LPNTT-----LTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNAL 125

Query: 114 ---HISLITPSFPTEGESQFVLQLRP---SLRGALLSLLDHYEWNCFVFLYDTDRGYSIL 167
              HI        ++ +  F + L P   SL  A+L L+  ++W     +YD   G   L
Sbjct: 126 GVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRL 185

Query: 168 QAIMEKAGQNGWHVSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVS 227
           Q +++   +    +  I     +    + LL+E+ R +E   + DC  E    IL+Q ++
Sbjct: 186 QELIKAPSRYNLRLK-IRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALA 244

Query: 228 VGKHVKGYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRW--KKLDQR 285
           +G   + YHYI   L    + +E + + G N+TGF++++     V  ++++W  ++L   
Sbjct: 245 MGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMERLQAP 304

Query: 286 EYPGSETPPKY---TSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQG 342
             P S     +    +AL YD V V++   +   +  +             N   PW  G
Sbjct: 305 PKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTV--------SSLQCNRHKPWRFG 356

Query: 343 IDMERTLKQVRIQGLTGNVQFDH-YGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQD 401
                 +K+   +GLTG + F+   G R ++ +DV  LK  G  K+G W+    L + + 
Sbjct: 357 TRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTES 416

Query: 402 VP-TLGNDTAAIENRTVVVTTIM 423
                 N T ++ NR+++VTTI+
Sbjct: 417 QKGKPANITDSLSNRSLIVTTIL 439


>gi|29029597 glutamate receptor KA2 precursor [Homo sapiens]
          Length = 980

 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 95/403 (23%), Positives = 162/403 (40%), Gaps = 44/403 (10%)

Query: 45  RLAIFLHNTSPNAS-EAPFNLVPHVD--NIETANSFAVTNAFCSQYSRGVFAIFGLYDK- 100
           RLA+ L     N   E P      VD   ++  + +  T+  C    +GV ++ G     
Sbjct: 41  RLALALAREQINGIIEVPAKARVEVDIFELQRDSQYETTDTMCQILPKGVVSVLGPSSSP 100

Query: 101 RSVHTLTSFCSALHISLITPSFPTEGESQFV----LQLRPSLRGALLS---LLDHYEW-- 151
            S  T++  C    I  I          Q++    + L PS     L+   +L  + +  
Sbjct: 101 ASASTVSHICGEKEIPHIKVGPEETPRLQYLRFASVSLYPSNEDVSLAVSRILKSFNYPS 160

Query: 152 --------NCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFNDVSYRQLLEELDR 203
                    C + L +  RG+ I +  +          S   +++  D +   LL+E+  
Sbjct: 161 ASLICAKAECLLRLEELVRGFLISKETL----------SVRMLDDSRDPT--PLLKEIRD 208

Query: 204 RQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIHGGANVTGFQ 263
            +    +ID        IL +   +G     Y YI+  + F  + L+  +   +N+ GF 
Sbjct: 209 DKVSTIIIDANASISHLILRKASELGMTSAFYKYILTTMDFPILHLDGIVEDSSNILGFS 268

Query: 264 LVDFNTPMVIKLMDRWKKLDQREYPGSET--PPKYTSALTYDGVLVMAETFRSLRRQKID 321
           + + + P   + + R   +  RE   + T   P  ++AL +D V V+    R L R    
Sbjct: 269 MFNTSHPFYPEFV-RSLNMSWRENCEASTYLGPALSAALMFDAVHVVVSAVRELNR---- 323

Query: 322 ISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRVNYTMDVFELKS 381
            S+           A  W  G  +   L+ V   GLTG V+F+  G+R NYT+ + E   
Sbjct: 324 -SQEIGVKPLACTSANIWPHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKSR 382

Query: 382 TGPRKVGYWNDMDKLVLIQDVPTLG-NDTAAIENRTVVVTTIM 423
            G R++G W       L  +  TL  N +  + N+T+VVTTI+
Sbjct: 383 QGHREIGVW--YSNRTLAMNATTLDINLSQTLANKTLVVTTIL 423


>gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens]
          Length = 1007

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 91/432 (21%), Positives = 171/432 (39%), Gaps = 45/432 (10%)

Query: 25  SSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVTNAFC 84
           S + IG +F  +  ++   FR A+   N +    +    +   V  ++  N F      C
Sbjct: 25  SIIHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTE-KITFSVTFVDGNNPFQAVQEAC 83

Query: 85  SQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLI-----TPSFPTEG--------ESQFV 131
              ++G+ A+       S  +L S   A+HI  +     T   P  G           + 
Sbjct: 84  ELMNQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRNDDYT 143

Query: 132 LQLRPS--LRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENF 189
           L +RP   L   +L ++  Y W  F+  YD++     +Q  ++K  Q G  V+   VEN 
Sbjct: 144 LSVRPPVYLHDVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKVSQQGMDVALQKVENN 203

Query: 190 NDVSYRQL-----LEELDRRQE--KKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANL 242
            +     L     +EEL+R ++  ++ ++       ++ + ++V         H+II N 
Sbjct: 204 INKMITTLFDTMRIEELNRYRDTLRRAILVMNPATAKSFITEVVETNLVAFDCHWIIINE 263

Query: 243 GFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPK------- 295
              D+ ++  +    ++    ++    P+   +  R  + + R    +   PK       
Sbjct: 264 EINDVDVQELVR--RSIGRLTIIRQTFPVPQNISQRCFRGNHR-ISSTLCDPKDPFAQNM 320

Query: 296 -YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAG--DCLANPAAPWGQGIDMERTLKQV 352
             ++   YD VL++A  F     +K++  +  +     C+   + PW  G  M  T+K+ 
Sbjct: 321 EISNLYIYDTVLLLANAF----HKKLEDRKWHSMASLSCIRKNSKPWQGGRSMLETIKKG 376

Query: 353 RIQGLTGNVQFDHYGRRVNYTMDVF-----ELKSTGPRKVGYWNDMDKLVLIQDVPTLGN 407
            + GLTG ++F   G   N   ++      E    G RK+G WN +  L        L N
Sbjct: 377 GVSGLTGELEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLNGSLTDKKLEN 436

Query: 408 DTAAIENRTVVV 419
           +   +  R V V
Sbjct: 437 NMRGVVLRVVTV 448


>gi|29029595 glutamate receptor KA1 precursor [Homo sapiens]
          Length = 956

 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 60/240 (25%), Positives = 103/240 (42%), Gaps = 18/240 (7%)

Query: 197 LLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIHGG 256
           LL+E+   +    +I         IL +   +G     Y YI  NL F    ++  +   
Sbjct: 203 LLKEIRDDKTATIIIHANASMSHTILLKAAELGMVSAYYTYIFTNLEFSLQRMDSLVDDR 262

Query: 257 ANVTGFQLVD----FNTPMVIKLMDRWKK-LDQREYPGSETPPKYTSALTYDGVLVMAET 311
            N+ GF + +    F       L   W++  D   + G    P  +SAL +D V  +   
Sbjct: 263 VNILGFSIFNQSHAFFQEFAQSLNQSWQENCDHVPFTG----PALSSALLFDAVYAVVTA 318

Query: 312 FRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRVN 371
            + L R     S+           A  W  G  +   L+ V ++GLTG+++F+  G+R N
Sbjct: 319 VQELNR-----SQEIGVKPLSCGSAQIWQHGTSLMNYLRMVELEGLTGHIEFNSKGQRSN 373

Query: 372 YTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIMPLMKNPIL 431
           Y + + +    G R++G W+  + L +   +    N +  + N T+VVTTI   ++NP L
Sbjct: 374 YALKILQFTRNGFRQIGQWHVAEGLSMDSHL-YASNISDTLFNTTLVVTTI---LENPYL 429


>gi|55770852 glutamate receptor, ionotropic, delta 1 precursor [Homo
           sapiens]
          Length = 1009

 Score = 68.9 bits (167), Expect = 8e-12
 Identities = 80/373 (21%), Positives = 142/373 (38%), Gaps = 45/373 (12%)

Query: 25  SSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVTNAFC 84
           S + IG +F  N  ++   F+LA+   + + +  ++   +   +  IE  N F      C
Sbjct: 22  SIIHIGAIFEENAAKDDRVFQLAVSDLSLNDDILQSE-KITYSIKVIEANNPFQAVQEAC 80

Query: 85  SQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQFVLQLRPS------- 137
              ++G+ A+       S + L S   A+HI  +       G  +    L PS       
Sbjct: 81  DLMTQGILALVTSTGCASANALQSLTDAMHIPHLFVQRNPGGSPRTACHLNPSPDGEAYT 140

Query: 138 --------LRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVEN- 188
                   L   +L L+    W  FV  YD++     LQ+ +++A + G  VS   V+  
Sbjct: 141 LASRPPVRLNDVMLRLVTELRWQKFVMFYDSEYDIRGLQSFLDQASRLGLDVSLQKVDKN 200

Query: 189 ----FNDVSYRQLLEELDRRQE--KKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANL 242
               F  +      EEL+R ++  ++ ++    +   + + + V      K  H++  N 
Sbjct: 201 ISHVFTSLFTTMKTEELNRYRDTLRRAILLLSPQGAHSFINEAVETNLASKDSHWVFVNE 260

Query: 243 GFKDISLERFIHGG-----------ANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSE 291
              D  +   +H              +    Q    N   +  L+      D +E  G  
Sbjct: 261 EISDPEILDLVHSALGRMTVVRQIFPSAKDNQKCTRNNHRISSLL-----CDPQE--GYL 313

Query: 292 TPPKYTSALTYDGVLVMAETF-RSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLK 350
              + ++   YD VL++A  F R L  +K       N   C+     PW  G  M  T+K
Sbjct: 314 QMLQISNLYLYDSVLMLANAFHRKLEDRKWHSMASLN---CIRKSTKPWNGGRSMLDTIK 370

Query: 351 QVRIQGLTGNVQF 363
           +  I GLTG ++F
Sbjct: 371 KGHITGLTGVMEF 383


>gi|167003331 N-methyl-D-aspartate receptor subunit 2B precursor
           [Homo sapiens]
          Length = 1484

 Score = 35.8 bits (81), Expect = 0.078
 Identities = 35/161 (21%), Positives = 64/161 (39%), Gaps = 20/161 (12%)

Query: 99  DKRSVHTLTSFCSALHISLITPSFPTEG----------ESQFVLQLRPSLR---GALLSL 145
           D+ ++  +  F SA     +TP     G          ES    Q  PS+      +L++
Sbjct: 104 DQEAIAQILDFISA---QTLTPILGIHGGSSMIMADKDESSMFFQFGPSIEQQASVMLNI 160

Query: 146 LDHYEWNCFVFLYDTDRGYSILQAIMEKAGQN---GWHVSAICVENFN-DVSYRQLLEEL 201
           ++ Y+W  F  +     GY      +    +N   GW +  + + + + D    ++  +L
Sbjct: 161 MEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVGWELEEVLLLDMSLDDGDSKIQNQL 220

Query: 202 DRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANL 242
            + Q    ++ C  E    I E   SVG    GY +I+ +L
Sbjct: 221 KKLQSPIILLYCTKEEATYIFEVANSVGLTGYGYTWIVPSL 261


>gi|112789566 taste receptor, type 1, member 2 [Homo sapiens]
          Length = 839

 Score = 29.3 bits (64), Expect = 7.3
 Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 8/85 (9%)

Query: 85  SQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTE---GESQFVLQLRPSLRG- 140
           S Y   V A+ G  +  SV T+ +F S   +  IT S  ++    + +F   LR +    
Sbjct: 129 SNYISRVVAVIGPDNSESVMTVANFLSLFLLPQITYSAISDELRDKVRFPALLRTTPSAD 188

Query: 141 ----ALLSLLDHYEWNCFVFLYDTD 161
               A++ L+ H+ WN  + L  +D
Sbjct: 189 HHIEAMVQLMLHFRWNWIIVLVSSD 213


>gi|87116668 hypothetical protein LOC9870 [Homo sapiens]
          Length = 823

 Score = 29.3 bits (64), Expect = 7.3
 Identities = 17/74 (22%), Positives = 31/74 (41%)

Query: 43  AFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRS 102
           AFR+ +F  N  P  +  P  L  H+ ++E A    VT     + +  V  +     K  
Sbjct: 77  AFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQEPNSNVVKVAFTVRKAG 136

Query: 103 VHTLTSFCSALHIS 116
            + +T     L+++
Sbjct: 137 RYEITVKLGGLNVA 150


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.138    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,415,103
Number of Sequences: 37866
Number of extensions: 656327
Number of successful extensions: 1391
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1323
Number of HSP's gapped (non-prelim): 24
length of query: 433
length of database: 18,247,518
effective HSP length: 105
effective length of query: 328
effective length of database: 14,271,588
effective search space: 4681080864
effective search space used: 4681080864
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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