BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [Homo sapiens] (691 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [H... 1428 0.0 gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [H... 1174 0.0 gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens] 57 4e-08 gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens] 57 6e-08 gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens] 50 5e-06 gi|15834621 F-box only protein 4 isoform 2 [Homo sapiens] 50 7e-06 gi|15834619 F-box only protein 4 isoform 1 [Homo sapiens] 50 7e-06 gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ... 48 3e-05 gi|27312027 F-box only protein 16 [Homo sapiens] 47 5e-05 gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens] 47 8e-05 gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens] 47 8e-05 gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens] 47 8e-05 gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ... 45 2e-04 gi|118150678 epithelial cell transforming sequence 2 oncogene-li... 42 0.001 gi|219281831 F-box protein 15 isoform 2 [Homo sapiens] 41 0.003 gi|22749363 F-box protein 15 isoform 1 [Homo sapiens] 41 0.003 gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [H... 40 0.006 gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [H... 40 0.006 gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens] 40 0.007 gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens] 39 0.012 gi|48928044 F-box only protein 8 [Homo sapiens] 38 0.027 gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens] 38 0.036 gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens] 38 0.036 gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ... 37 0.061 gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ... 37 0.061 gi|30520327 F-box protein 27 [Homo sapiens] 37 0.080 gi|190194416 F-box and leucine-rich repeat protein 15 [Homo sapi... 36 0.10 gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens] 36 0.10 gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi... 36 0.14 gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [... 35 0.18 >gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [Homo sapiens] Length = 691 Score = 1428 bits (3697), Expect = 0.0 Identities = 691/691 (100%), Positives = 691/691 (100%) Query: 1 MAPFPEEVDVFTAPHWRMKQLVGLYCDKLSKTNFSNNNDFRALLQSLYATFKEFKMHEQI 60 MAPFPEEVDVFTAPHWRMKQLVGLYCDKLSKTNFSNNNDFRALLQSLYATFKEFKMHEQI Sbjct: 1 MAPFPEEVDVFTAPHWRMKQLVGLYCDKLSKTNFSNNNDFRALLQSLYATFKEFKMHEQI 60 Query: 61 ENEYIIGLLQQRSQTIYNVHSDNKLSEMLSLFEKGLKNVKNEYEQLNYAKQLKERLEAFT 120 ENEYIIGLLQQRSQTIYNVHSDNKLSEMLSLFEKGLKNVKNEYEQLNYAKQLKERLEAFT Sbjct: 61 ENEYIIGLLQQRSQTIYNVHSDNKLSEMLSLFEKGLKNVKNEYEQLNYAKQLKERLEAFT 120 Query: 121 RDFLPHMKEEEEVFQPMLMEYFTYEELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEER 180 RDFLPHMKEEEEVFQPMLMEYFTYEELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEER Sbjct: 121 RDFLPHMKEEEEVFQPMLMEYFTYEELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEER 180 Query: 181 QKFFKYSVDEKSDKEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTK 240 QKFFKYSVDEKSDKEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTK Sbjct: 181 QKFFKYSVDEKSDKEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTK 240 Query: 241 TGSLWKHLYPVHWARGDWYSGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEES 300 TGSLWKHLYPVHWARGDWYSGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEES Sbjct: 241 TGSLWKHLYPVHWARGDWYSGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEES 300 Query: 301 AEESIAISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEH 360 AEESIAISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEH Sbjct: 301 AEESIAISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEH 360 Query: 361 LDLTQTDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTSHQSGFLK 420 LDLTQTDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTSHQSGFLK Sbjct: 361 LDLTQTDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTSHQSGFLK 420 Query: 421 TSTSKITSTAWKNKDITMQSTKQYACLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVW 480 TSTSKITSTAWKNKDITMQSTKQYACLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVW Sbjct: 421 TSTSKITSTAWKNKDITMQSTKQYACLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVW 480 Query: 481 MLDAEDLADIEDTVEWRHRNVESLCVMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCAS 540 MLDAEDLADIEDTVEWRHRNVESLCVMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCAS Sbjct: 481 MLDAEDLADIEDTVEWRHRNVESLCVMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCAS 540 Query: 541 PAFAYCGHSFCCTGTALRTMSSLPESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVL 600 PAFAYCGHSFCCTGTALRTMSSLPESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVL Sbjct: 541 PAFAYCGHSFCCTGTALRTMSSLPESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVL 600 Query: 601 LFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFY 660 LFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFY Sbjct: 601 LFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFY 660 Query: 661 YCDNINGPHADTASGCQNLQCGFRACCRSGE 691 YCDNINGPHADTASGCQNLQCGFRACCRSGE Sbjct: 661 YCDNINGPHADTASGCQNLQCGFRACCRSGE 691 >gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [Homo sapiens] Length = 565 Score = 1174 bits (3036), Expect = 0.0 Identities = 565/565 (100%), Positives = 565/565 (100%) Query: 127 MKEEEEVFQPMLMEYFTYEELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEERQKFFKY 186 MKEEEEVFQPMLMEYFTYEELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEERQKFFKY Sbjct: 1 MKEEEEVFQPMLMEYFTYEELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEERQKFFKY 60 Query: 187 SVDEKSDKEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWK 246 SVDEKSDKEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWK Sbjct: 61 SVDEKSDKEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWK 120 Query: 247 HLYPVHWARGDWYSGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEESAEESIA 306 HLYPVHWARGDWYSGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEESAEESIA Sbjct: 121 HLYPVHWARGDWYSGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEESAEESIA 180 Query: 307 ISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQT 366 ISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQT Sbjct: 181 ISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQT 240 Query: 367 DISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTSHQSGFLKTSTSKI 426 DISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTSHQSGFLKTSTSKI Sbjct: 241 DISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTSHQSGFLKTSTSKI 300 Query: 427 TSTAWKNKDITMQSTKQYACLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVWMLDAED 486 TSTAWKNKDITMQSTKQYACLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVWMLDAED Sbjct: 301 TSTAWKNKDITMQSTKQYACLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVWMLDAED 360 Query: 487 LADIEDTVEWRHRNVESLCVMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCASPAFAYC 546 LADIEDTVEWRHRNVESLCVMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCASPAFAYC Sbjct: 361 LADIEDTVEWRHRNVESLCVMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCASPAFAYC 420 Query: 547 GHSFCCTGTALRTMSSLPESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVLLFLSLS 606 GHSFCCTGTALRTMSSLPESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVLLFLSLS Sbjct: 421 GHSFCCTGTALRTMSSLPESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVLLFLSLS 480 Query: 607 GCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNIN 666 GCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNIN Sbjct: 481 GCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNIN 540 Query: 667 GPHADTASGCQNLQCGFRACCRSGE 691 GPHADTASGCQNLQCGFRACCRSGE Sbjct: 541 GPHADTASGCQNLQCGFRACCRSGE 565 >gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens] Length = 423 Score = 57.4 bits (137), Expect = 4e-08 Identities = 52/199 (26%), Positives = 80/199 (40%), Gaps = 62/199 (31%) Query: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHWARGDWYSGPATELD 267 LP E++L IFS+L+ LCRC+Q+S W+ L GS +W R D ++ ++D Sbjct: 15 LPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGS--------NWQRIDLFN---FQID 63 Query: 268 TEPDDEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVLPY 327 E ++ N+ Sbjct: 64 VEGR------------------------------------------------VVENISKR 75 Query: 328 VGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQ-TDISDSAFDSWSWLGCCQSLR 386 G ++ L L V ++ + C N+EHL+L T I+DS S S C L+ Sbjct: 76 CGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRF--CSKLK 133 Query: 387 HLDLSGCEKITDVALEKIS 405 HLDL+ C IT+ +L+ IS Sbjct: 134 HLDLTSCVSITNSSLKGIS 152 Score = 41.2 bits (95), Expect = 0.003 Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 3/93 (3%) Query: 589 SEKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLV 648 S K+ + R + L+L+GC +ITD +L L+HL+L+ C++IT + L+ + Sbjct: 95 SLKTFAQNCRNIEHLNLNGCTKITDS--TCYSLSRFCSKLKHLDLTSCVSITNSSLKGIS 152 Query: 649 SACPSLNDEYFYYCDNINGPHADT-ASGCQNLQ 680 C +L +CD I + GC+ L+ Sbjct: 153 EGCRNLEYLNLSWCDQITKDGIEALVRGCRGLK 185 Score = 36.6 bits (83), Expect = 0.080 Identities = 23/55 (41%), Positives = 30/55 (54%), Gaps = 2/55 (3%) Query: 600 LLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSL 654 L+ L+L C +ITD G V+ + G L+ L LSGC +T A L L CP L Sbjct: 210 LVSLNLQSCSRITDEG--VVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRL 262 Score = 32.3 bits (72), Expect = 1.5 Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 2/58 (3%) Query: 355 CPNLEHLDLTQTD-ISDSAFDSWSWLGCC-QSLRHLDLSGCEKITDVALEKISRALGI 410 CP L+ L L+ + I+D S C + LR L+L C ITDVALE + G+ Sbjct: 311 CPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHLENCRGL 368 Score = 32.0 bits (71), Expect = 2.0 Identities = 12/25 (48%), Positives = 18/25 (72%) Query: 382 CQSLRHLDLSGCEKITDVALEKISR 406 C+++ HL+L+GC KITD +SR Sbjct: 103 CRNIEHLNLNGCTKITDSTCYSLSR 127 Score = 30.4 bits (67), Expect = 5.7 Identities = 24/83 (28%), Positives = 33/83 (39%), Gaps = 5/83 (6%) Query: 600 LLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYF 659 L L + C +TD G +L LE ++L C+ IT + L L CP L Sbjct: 262 LQILEAARCSHLTDAGFTLLARN--CHELEKMDLEECILITDSTLIQLSIHCPKLQALSL 319 Query: 660 YYCDNINGPHADTASGCQNLQCG 682 +C+ I D N CG Sbjct: 320 SHCELITD---DGILHLSNSTCG 339 Score = 30.0 bits (66), Expect = 7.5 Identities = 37/125 (29%), Positives = 43/125 (34%), Gaps = 27/125 (21%) Query: 589 SEKSDQETGRVLLFLSLSGCYQITDHGLRVLTLG---------GGLPYLEH--------- 630 S K E R L +L+LS C QIT G+ L G G LE Sbjct: 147 SLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNY 206 Query: 631 ------LNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADTASG--CQNLQCG 682 LNL C IT G+ + C L C N+ TA G C LQ Sbjct: 207 CHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASL-TALGLNCPRLQIL 265 Query: 683 FRACC 687 A C Sbjct: 266 EAARC 270 >gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens] Length = 436 Score = 57.0 bits (136), Expect = 6e-08 Identities = 53/205 (25%), Positives = 80/205 (39%), Gaps = 62/205 (30%) Query: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHWARGDWYSGPATELD 267 LP E++L IFS+L+ LCRC+QVS W+ L GS +W R D + Sbjct: 28 LPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGS--------NWQRIDLF-------- 71 Query: 268 TEPDDEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVLPY 327 D DI+ ++ N+ Sbjct: 72 ---------------------DFQRDIEGR----------------------VVENISKR 88 Query: 328 VGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQ-TDISDSAFDSWSWLGCCQSLR 386 G ++ L L V +R + C N+E L+L T +D+ S S C LR Sbjct: 89 CGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKF--CSKLR 146 Query: 387 HLDLSGCEKITDVALEKISRALGIL 411 HLDL+ C IT+++L+ +S +L Sbjct: 147 HLDLASCTSITNMSLKALSEGCPLL 171 Score = 41.2 bits (95), Expect = 0.003 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 2/66 (3%) Query: 600 LLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYF 659 L L L+ C IT+ L+ L+ G P LE LN+S C +T G+Q LV C L + Sbjct: 145 LRHLDLASCTSITNMSLKALS--EGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFL 202 Query: 660 YYCDNI 665 C + Sbjct: 203 KGCTQL 208 Score = 39.7 bits (91), Expect = 0.009 Identities = 30/82 (36%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Query: 600 LLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYF 659 L+ L+L C QITD GL +T+ G L+ L SGC IT A L L CP L Sbjct: 223 LVTLNLQTCLQITDEGL--ITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEV 280 Query: 660 YYCDNINGPHADT-ASGCQNLQ 680 C + T A C L+ Sbjct: 281 ARCSQLTDVGFTTLARNCHELE 302 Score = 38.5 bits (88), Expect = 0.021 Identities = 24/63 (38%), Positives = 28/63 (44%), Gaps = 2/63 (3%) Query: 603 LSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYC 662 L L GC Q+ D L+ + G P L LNL CL IT GL + C L C Sbjct: 200 LFLKGCTQLEDEALKYI--GAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGC 257 Query: 663 DNI 665 NI Sbjct: 258 SNI 260 Score = 37.4 bits (85), Expect = 0.047 Identities = 29/67 (43%), Positives = 32/67 (47%), Gaps = 2/67 (2%) Query: 600 LLFLSLSGCYQITDHGLRVLTLGG-GLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEY 658 L LSLS C ITD G+R L G LE + L C IT A L+ L S C SL Sbjct: 327 LQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKS-CHSLERIE 385 Query: 659 FYYCDNI 665 Y C I Sbjct: 386 LYDCQQI 392 Score = 36.2 bits (82), Expect = 0.10 Identities = 29/92 (31%), Positives = 36/92 (39%), Gaps = 3/92 (3%) Query: 590 EKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVS 649 E + G L LSL GC + D+ LR T +E LNL+GC T A L Sbjct: 83 ENISKRCGGFLRKLSLRGCLGVGDNALR--TFAQNCRNIEVLNLNGCTKTTDATCTSLSK 140 Query: 650 ACPSLNDEYFYYCDNINGPHADTAS-GCQNLQ 680 C L C +I S GC L+ Sbjct: 141 FCSKLRHLDLASCTSITNMSLKALSEGCPLLE 172 Score = 32.7 bits (73), Expect = 1.2 Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 2/66 (3%) Query: 600 LLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYF 659 L L ++ C Q+TD G TL LE ++L C+ IT + L L CP L Sbjct: 275 LRILEVARCSQLTDVGFT--TLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSL 332 Query: 660 YYCDNI 665 +C+ I Sbjct: 333 SHCELI 338 >gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens] Length = 491 Score = 50.4 bits (119), Expect = 5e-06 Identities = 92/453 (20%), Positives = 157/453 (34%), Gaps = 109/453 (24%) Query: 200 EHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHWARGDWY 259 + I LP M+ IFS+L +LCRC++V +W Y + W W Sbjct: 109 KEQASIDRLPDHSMVQIFSFLPTNQLCRCARVCRRW-------------YNLAWDPRLW- 154 Query: 260 SGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHG 319 R E ++D + + + +RL Sbjct: 155 -----------------------RTIRLTGETINVDRA-----------LKVLTRRLCQD 180 Query: 320 LIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQT-DISDSAFDSWSW 378 P V ++T+ ++ ++ + + I + CP L L+++ +IS+ A + Sbjct: 181 T-----PNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAV--FDV 233 Query: 379 LGCCQSLRHLDLSGCEKITDVALEKISRALGILTSHQSGFLKTSTSKITSTAWKNKDITM 438 + C +L HLD+SGC K+T ++L T + I + K I++ Sbjct: 234 VSLCPNLEHLDVSGCSKVTCISL-------------------TREASIKLSPLHGKQISI 274 Query: 439 QSTKQYACLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVWMLDAEDLADIEDTVEWRH 498 + C +++E T T Y + V Sbjct: 275 RYLDMTDCF----------VLEDEGLHTIAAHCTQLTHLY-----------LRRCVRLTD 313 Query: 499 RNVESLCVMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCASPAFAYCGHSFCCTGTALR 558 + L V+ AS S S C GLR + + A+CG T +R Sbjct: 314 EGLRYL-VIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGR---VTDVGIR 369 Query: 559 TMSSLPESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVLLFLSLSGCYQITDHGLRV 618 ++ C K + + G E + + L L + C ++D GL Sbjct: 370 YVAK------YCSKLRYLNARGCEGITDHGVEYLAKNCTK-LKSLDIGKCPLVSDTGLEC 422 Query: 619 LTLGGGLPYLEHLNLSGCLTITGAGLQDLVSAC 651 L L L+ L+L C +ITG GLQ + + C Sbjct: 423 LAL--NCFNLKRLSLKSCESITGQGLQIVAANC 453 Score = 47.4 bits (111), Expect = 5e-05 Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 19/91 (20%) Query: 594 QETGRVLLFL---SLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSA 650 Q+T V L L ++SGC ++TD GL T+ P L L +SGC I+ + D+VS Sbjct: 179 QDTPNVCLMLETVTVSGCRRLTDRGL--YTIAQCCPELRRLEVSGCYNISNEAVFDVVSL 236 Query: 651 CPSLNDEYFYYCDNINGPHADTASGCQNLQC 681 CP+L H D SGC + C Sbjct: 237 CPNLE-------------HLD-VSGCSKVTC 253 Score = 37.4 bits (85), Expect = 0.047 Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 3/82 (3%) Query: 600 LLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYF 659 L +L+ GC ITDHG+ L L+ L++ C ++ GL+ L C +L Sbjct: 378 LRYLNARGCEGITDHGVEY--LAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSL 435 Query: 660 YYCDNINGPHAD-TASGCQNLQ 680 C++I G A+ C +LQ Sbjct: 436 KSCESITGQGLQIVAANCFDLQ 457 Score = 35.8 bits (81), Expect = 0.14 Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 2/55 (3%) Query: 602 FLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLND 656 +L ++ C+ + D GL T+ L HL L C+ +T GL+ LV C S+ + Sbjct: 276 YLDMTDCFVLEDEGLH--TIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCASIKE 328 Score = 35.8 bits (81), Expect = 0.14 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%) Query: 600 LLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYF 659 L +LS++ C ++TD G+R + L +LN GC IT G++ L C L Sbjct: 352 LRYLSIAHCGRVTDVGIRY--VAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDI 409 Query: 660 YYCDNINGPHADTASGCQNLQC 681 C + +DT C L C Sbjct: 410 GKCPLV----SDTGLECLALNC 427 >gi|15834621 F-box only protein 4 isoform 2 [Homo sapiens] Length = 307 Score = 50.1 bits (118), Expect = 7e-06 Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 3/86 (3%) Query: 191 KSDKEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLY- 249 ++ EV E ++ +T LP +V L I S+L+P +LC+ + W++ + LW++ Sbjct: 45 RTTSREEVDEAASTLTRLPIDVQLYILSFLSPHDLCQLGSTNHYWNETVRDPILWRYFLL 104 Query: 250 --PVHWARGDWYSGPATELDTEPDDE 273 W+ DW S P E+ +P E Sbjct: 105 RDLPSWSSVDWKSLPDLEILKKPISE 130 >gi|15834619 F-box only protein 4 isoform 1 [Homo sapiens] Length = 387 Score = 50.1 bits (118), Expect = 7e-06 Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 3/86 (3%) Query: 191 KSDKEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLY- 249 ++ EV E ++ +T LP +V L I S+L+P +LC+ + W++ + LW++ Sbjct: 45 RTTSREEVDEAASTLTRLPIDVQLYILSFLSPHDLCQLGSTNHYWNETVRDPILWRYFLL 104 Query: 250 --PVHWARGDWYSGPATELDTEPDDE 273 W+ DW S P E+ +P E Sbjct: 105 RDLPSWSSVDWKSLPDLEILKKPISE 130 >gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 [Homo sapiens] Length = 690 Score = 48.1 bits (113), Expect = 3e-05 Identities = 121/565 (21%), Positives = 211/565 (37%), Gaps = 73/565 (12%) Query: 156 AQHCSQKDTAELLRGLSLWNHAEERQKFFKYSVDEKSDKEAEVSEH--------STGITH 207 A+H S+K EL+ L + + K + E+S+ S I+ Sbjct: 98 ARHKSKKKEDELILKHELQLKKWKNRLILKRAAAEESNFPERSSSEVFLVDETLKCDISL 157 Query: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLW--------KHLYPVHWARGDWY 259 LP +L IF YL+ +++ C QV+ W +T+ SLW K++ P + Sbjct: 158 LPERAILQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFSSVKNVIPDKYIVSTLQ 217 Query: 260 SGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEESAEESI--------AISIAQ 311 L ++ + S + ++ ++ + +ES+ + Sbjct: 218 RWRLNVLRLNFRGCLLRPKTFRSVSHCRNLQELNVSDCPTFTDESMRHISEGCPGVLCLN 277 Query: 312 MEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILEL---CPNLEHLDLTQ-TD 367 + + +LP +++ L LAY + K + Q L L C L +LDL+ T Sbjct: 278 LSNTTITNRTMRLLPRHFHNLQNLSLAYCRRFTDKGL-QYLNLGNGCHKLIYLDLSGCTQ 336 Query: 368 ISDSAFDSWSWLGCCQSLRHLDLSGCEKITD----VALEKISRALGIL---TSHQSG--F 418 IS F + C + HL ++ +TD +EK SR ++ H S F Sbjct: 337 ISVQGFRYIA--NSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTF 394 Query: 419 LKTSTSKITSTAWK-NKDITMQSTK-------QYACLHDLTNKGIGEEIDNEHPWTKPVS 470 S K+ ++ NK +T S K + ++ KGI + K ++ Sbjct: 395 RALSACKLRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQLT 454 Query: 471 SENFTS-PYVWMLDAEDLADIEDTVEWRHRNVESLCVMETASNFSCSTSGCFSKDIVGLR 529 N + + + + D ++ R N+ S CV + ++ + C + + + LR Sbjct: 455 VLNLANCVRIGDMGLKQFLDGPASMRIRELNL-SNCVRLSDASVMKLSERCPNLNYLSLR 513 Query: 530 TSVCWQQHCASPAFAYCGHSFCCTGTALRTMSSLPESSAMCRKAARTRLPRGKDLIYFGS 589 +H + Y + F ++ S+ S L R K L Sbjct: 514 NC----EHLTAQGIGYIVNIF--------SLVSIDLSGTDISNEGLNVLSRHKKL----K 557 Query: 590 EKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVS 649 E S E R+ QITD + +L+ YL L++SGC+ +T L+DL Sbjct: 558 ELSVSECYRI-----TDDGIQITDSAMEMLS--AKCHYLHILDISGCVLLTDQILEDLQI 610 Query: 650 ACPSLNDEYFYYCDNINGPHADTAS 674 C L YC NI+ A S Sbjct: 611 GCKQLRILKMQYCTNISKKAAQRMS 635 Score = 32.3 bits (72), Expect = 1.5 Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 2/78 (2%) Query: 600 LLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYF 659 L++L LSGC QI+ G R + + HL ++ T+T ++ LV C + F Sbjct: 326 LIYLDLSGCTQISVQGFRY--IANSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLVF 383 Query: 660 YYCDNINGPHADTASGCQ 677 +I+ S C+ Sbjct: 384 TGAPHISDCTFRALSACK 401 >gi|27312027 F-box only protein 16 [Homo sapiens] Length = 292 Score = 47.4 bits (111), Expect = 5e-05 Identities = 29/80 (36%), Positives = 39/80 (48%), Gaps = 9/80 (11%) Query: 180 RQKFFKYSVDEKSDKEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLT 239 +QKF + EK EA T LP + L IFS+L+P+ LCRC+QV W L Sbjct: 69 QQKFCCRKLQEKIPAEA-----LDFTTKLPRVLSLYIFSFLDPRSLCRCAQVCWHWKNLA 123 Query: 240 KTGSLWKHLYPVHWARGDWY 259 + LW + R +WY Sbjct: 124 ELDQLWM----LKCLRFNWY 139 >gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens] Length = 843 Score = 46.6 bits (109), Expect = 8e-05 Identities = 22/42 (52%), Positives = 28/42 (66%) Query: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLY 249 LP EV+L IFSYL Q+LCR + V ++S+L LWK LY Sbjct: 75 LPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLY 116 >gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens] Length = 686 Score = 46.6 bits (109), Expect = 8e-05 Identities = 22/42 (52%), Positives = 28/42 (66%) Query: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLY 249 LP EV+L IFSYL Q+LCR + V ++S+L LWK LY Sbjct: 75 LPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLY 116 >gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens] Length = 585 Score = 46.6 bits (109), Expect = 8e-05 Identities = 22/42 (52%), Positives = 28/42 (66%) Query: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLY 249 LP EV+L IFSYL Q+LCR + V ++S+L LWK LY Sbjct: 75 LPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLY 116 >gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 [Homo sapiens] Length = 735 Score = 45.4 bits (106), Expect = 2e-04 Identities = 27/75 (36%), Positives = 39/75 (52%), Gaps = 2/75 (2%) Query: 600 LLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYF 659 L LS++GC +ITD + +L+ YL L++SGC+ +T L+DL C L Sbjct: 608 LTSLSIAGCPKITDSAMEMLS--AKCHYLHILDISGCVLLTDQILEDLQIGCKQLRILKM 665 Query: 660 YYCDNINGPHADTAS 674 YC NI+ A S Sbjct: 666 QYCTNISKKAAQRMS 680 Score = 43.5 bits (101), Expect = 7e-04 Identities = 21/52 (40%), Positives = 32/52 (61%) Query: 603 LSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSL 654 LSL+ C + TD GL+ L LG G L +L+LSGC I+ G + + ++C + Sbjct: 301 LSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRYIANSCTGI 352 Score = 41.2 bits (95), Expect = 0.003 Identities = 21/66 (31%), Positives = 34/66 (51%) Query: 600 LLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYF 659 L L+L+ C +I D GL+ G + LNLS C+ ++ A + L CP+LN Sbjct: 453 LTVLNLANCVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNLNYLSL 512 Query: 660 YYCDNI 665 C+++ Sbjct: 513 RNCEHL 518 Score = 38.1 bits (87), Expect = 0.027 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 8/98 (8%) Query: 156 AQHCSQKDTAELLRGLSLWNHAEERQKFFKYSVDEKSDKEAEVSEH--------STGITH 207 A+H S+K EL+ L + + K + E+S+ S I+ Sbjct: 98 ARHKSKKKEDELILKHELQLKKWKNRLILKRAAAEESNFPERSSSEVFLVDETLKCDISL 157 Query: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLW 245 LP +L IF YL+ +++ C QV+ W +T+ SLW Sbjct: 158 LPERAILQIFFYLSLKDVIICGQVNHAWMLMTQLNSLW 195 Score = 36.6 bits (83), Expect = 0.080 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 3/71 (4%) Query: 335 LVLAYSSAVSSKMVRQILELCPNLEHLDLTQTD-ISDSAFDSWSWLGCCQSLRHLDLSGC 393 L ++Y S +S +++ + C NL L + I+DSA + S C L LD+SGC Sbjct: 585 LDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPKITDSAMEMLS--AKCHYLHILDISGC 642 Query: 394 EKITDVALEKI 404 +TD LE + Sbjct: 643 VLLTDQILEDL 653 Score = 35.8 bits (81), Expect = 0.14 Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 13/135 (9%) Query: 518 SGCFSKDIVGLRTSVCWQQHCASPAFAYCGHSFCCTGTALRTMSSLPESSAMCRKAARTR 577 +GC ++ L S C Q + F Y +S CTG T++ +P + C KA + Sbjct: 321 NGCHK--LIYLDLSGCTQ--ISVQGFRYIANS--CTGIMHLTINDMPTLTDNCVKALVEK 374 Query: 578 LPRGKDLIYFGSEKSDQETGRVLLFLSL-----SGCYQITDHGLRVLTLGGGLPYLEHLN 632 R L++ G+ T R L L G ++TD + + P L H+ Sbjct: 375 CSRITSLVFTGAPHISDCTFRALSACKLRKIRFEGNKRVTDASFKF--IDKNYPNLSHIY 432 Query: 633 LSGCLTITGAGLQDL 647 ++ C IT + L+ L Sbjct: 433 MADCKGITDSSLRSL 447 Score = 33.5 bits (75), Expect = 0.68 Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 6/81 (7%) Query: 603 LSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYC 662 LS+S CY+ITD G++ + LEHL++S C ++ ++ L C +L C Sbjct: 559 LSVSECYRITDDGIQAFCKSSLI--LEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGC 616 Query: 663 DNINGPHADTASGCQNLQCGF 683 I D+A + +C + Sbjct: 617 PKI----TDSAMEMLSAKCHY 633 Score = 32.7 bits (73), Expect = 1.2 Identities = 19/49 (38%), Positives = 30/49 (61%), Gaps = 3/49 (6%) Query: 358 LEHLDLTQ-TDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVALEKIS 405 LEHLD++ + +SD + + C +L L ++GC KITD A+E +S Sbjct: 582 LEHLDVSYCSQLSDMIIKALAIY--CINLTSLSIAGCPKITDSAMEMLS 628 Score = 32.3 bits (72), Expect = 1.5 Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 2/78 (2%) Query: 600 LLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYF 659 L++L LSGC QI+ G R + + HL ++ T+T ++ LV C + F Sbjct: 326 LIYLDLSGCTQISVQGFRY--IANSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLVF 383 Query: 660 YYCDNINGPHADTASGCQ 677 +I+ S C+ Sbjct: 384 TGAPHISDCTFRALSACK 401 >gi|118150678 epithelial cell transforming sequence 2 oncogene-like [Homo sapiens] Length = 904 Score = 42.4 bits (98), Expect = 0.001 Identities = 19/40 (47%), Positives = 26/40 (65%) Query: 206 THLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLW 245 T LP + L IFS+L+P++LC +QVS W LT+ LW Sbjct: 79 TVLPRFISLYIFSFLSPKDLCAAAQVSWPWKFLTEQDCLW 118 >gi|219281831 F-box protein 15 isoform 2 [Homo sapiens] Length = 510 Score = 41.2 bits (95), Expect = 0.003 Identities = 49/197 (24%), Positives = 79/197 (40%), Gaps = 39/197 (19%) Query: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHW--ARGDWYSGPATE 265 +P E++L IFSYL+ L VS ++ L +W +Y + AR +W + Sbjct: 77 MPSEILLKIFSYLDAVSLLCTGCVSRRFYHLANDNFIWIGIYSTAFSPARSNWKFNSVEK 136 Query: 266 LDTEPDDEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVL 325 + V+++ E+ +E I IA + K L ++ V Sbjct: 137 IAMSMSFLSVQDK-----------------EAGYWKKEYITKQIASV-KAALADILKPVN 178 Query: 326 PYVGTSVKT------LVLAYSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWL 379 PY G VKT L ++ + K ++ + +EH+DL+ D S + W Sbjct: 179 PYTGLPVKTKEALRIFGLGWAIILKEKGGKEYI-----MEHVDLSINDTSVTVI----WY 229 Query: 380 G----CCQSLRHLDLSG 392 G C SL LDL G Sbjct: 230 GKKWPCLASLSTLDLCG 246 >gi|22749363 F-box protein 15 isoform 1 [Homo sapiens] Length = 434 Score = 41.2 bits (95), Expect = 0.003 Identities = 49/197 (24%), Positives = 79/197 (40%), Gaps = 39/197 (19%) Query: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHW--ARGDWYSGPATE 265 +P E++L IFSYL+ L VS ++ L +W +Y + AR +W + Sbjct: 1 MPSEILLKIFSYLDAVSLLCTGCVSRRFYHLANDNFIWIGIYSTAFSPARSNWKFNSVEK 60 Query: 266 LDTEPDDEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVL 325 + V+++ E+ +E I IA + K L ++ V Sbjct: 61 IAMSMSFLSVQDK-----------------EAGYWKKEYITKQIASV-KAALADILKPVN 102 Query: 326 PYVGTSVKT------LVLAYSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWL 379 PY G VKT L ++ + K ++ + +EH+DL+ D S + W Sbjct: 103 PYTGLPVKTKEALRIFGLGWAIILKEKGGKEYI-----MEHVDLSINDTSVTVI----WY 153 Query: 380 G----CCQSLRHLDLSG 392 G C SL LDL G Sbjct: 154 GKKWPCLASLSTLDLCG 170 >gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [Homo sapiens] Length = 532 Score = 40.4 bits (93), Expect = 0.006 Identities = 18/41 (43%), Positives = 26/41 (63%) Query: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHL 248 LP E+ ++IF YL+ +EL RC+QVS W + + LW L Sbjct: 53 LPYELAINIFQYLDRKELGRCAQVSKTWKVIAEDEVLWYRL 93 >gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [Homo sapiens] Length = 598 Score = 40.4 bits (93), Expect = 0.006 Identities = 18/41 (43%), Positives = 26/41 (63%) Query: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHL 248 LP E+ ++IF YL+ +EL RC+QVS W + + LW L Sbjct: 119 LPYELAINIFQYLDRKELGRCAQVSKTWKVIAEDEVLWYRL 159 >gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens] Length = 621 Score = 40.0 bits (92), Expect = 0.007 Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 5/104 (4%) Query: 331 SVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWLGC-CQSLRHLD 389 S+K LVL Y + V + IL C L+HL L + + S +G C+ LR LD Sbjct: 427 SLKRLVL-YRTKVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLD 485 Query: 390 LSGCEKITDVALEKISRALGILTSHQSGF---LKTSTSKITSTA 430 L C+ IT+ + +++ +L G+ L++ST T A Sbjct: 486 LWRCKNITENGIAELASGCPLLEELDLGWCPTLQSSTGCFTRLA 529 Score = 32.3 bits (72), Expect = 1.5 Identities = 26/97 (26%), Positives = 39/97 (40%), Gaps = 23/97 (23%) Query: 325 LPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQTD-ISDSAFDS-------- 375 L G+ + L L+ S ++ + I E+CPNL+ L+L+ D + AF+ Sbjct: 370 LKVCGSELVRLELSCSHFLNETCLEVISEMCPNLQALNLSSCDKLPPQAFNHIAKLCSLK 429 Query: 376 --------------WSWLGCCQSLRHLDLSGCEKITD 398 S L C L+HL L C I D Sbjct: 430 RLVLYRTKVEQTALLSILNFCSELQHLSLGSCVMIED 466 >gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens] Length = 326 Score = 39.3 bits (90), Expect = 0.012 Identities = 17/44 (38%), Positives = 26/44 (59%) Query: 205 ITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHL 248 + LP V+L IFSYL ++ R S+V +W +L LW+H+ Sbjct: 4 LVELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHV 47 >gi|48928044 F-box only protein 8 [Homo sapiens] Length = 319 Score = 38.1 bits (87), Expect = 0.027 Identities = 21/67 (31%), Positives = 31/67 (46%), Gaps = 3/67 (4%) Query: 194 KEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHW 253 ++++ E + LPPE+ +I SYLN +LC S V W L LW+ L W Sbjct: 60 RKSKEQEGFINLEMLPPELSFTILSYLNATDLCLASCV---WQDLANDELLWQGLCKSTW 116 Query: 254 ARGDWYS 260 Y+ Sbjct: 117 GHCSIYN 123 >gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens] Length = 223 Score = 37.7 bits (86), Expect = 0.036 Identities = 35/139 (25%), Positives = 64/139 (46%), Gaps = 11/139 (7%) Query: 290 EDADIDESEESAEESIA-----ISIAQMEKRLLHGLIHNVLPYVGT---SVKTLVLAYSS 341 ++ D+ + + S+A + + Q+ LL L N L V S++ L L++ S Sbjct: 78 QELDLTACSKLTDASLAKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCS 137 Query: 342 AVSSKMVRQILELCPNLEHLDLTQ-TDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVA 400 +S K Q P L+HL+L+ + + + D+ C+ LR LD++ C I A Sbjct: 138 RLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIG--QACRQLRVLDVATCPGINMAA 195 Query: 401 LEKISRALGILTSHQSGFL 419 + + L ++ QS F+ Sbjct: 196 VRRFQAQLPQVSCVQSRFV 214 Score = 37.7 bits (86), Expect = 0.036 Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 8/105 (7%) Query: 589 SEKSDQETGRVLLFL-----SLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAG 643 S+ +D +VL FL SLS ++TD+GL + + G P LEHL LS C ++ G Sbjct: 86 SKLTDASLAKVLQFLQLRQLSLSLLPELTDNGL--VAVARGCPSLEHLALSHCSRLSDKG 143 Query: 644 LQDLVSACPSLNDEYFYYCDNINGPHADT-ASGCQNLQCGFRACC 687 S+ P L C + D C+ L+ A C Sbjct: 144 WAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATC 188 Score = 32.3 bits (72), Expect = 1.5 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 2/64 (3%) Query: 603 LSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYC 662 L+LS C +++D G P L+HLNLS C + L + AC L C Sbjct: 131 LALSHCSRLSDKGWA--QAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATC 188 Query: 663 DNIN 666 IN Sbjct: 189 PGIN 192 >gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens] Length = 223 Score = 37.7 bits (86), Expect = 0.036 Identities = 35/139 (25%), Positives = 64/139 (46%), Gaps = 11/139 (7%) Query: 290 EDADIDESEESAEESIA-----ISIAQMEKRLLHGLIHNVLPYVGT---SVKTLVLAYSS 341 ++ D+ + + S+A + + Q+ LL L N L V S++ L L++ S Sbjct: 78 QELDLTACSKLTDASLAKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCS 137 Query: 342 AVSSKMVRQILELCPNLEHLDLTQ-TDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVA 400 +S K Q P L+HL+L+ + + + D+ C+ LR LD++ C I A Sbjct: 138 RLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIG--QACRQLRVLDVATCPGINMAA 195 Query: 401 LEKISRALGILTSHQSGFL 419 + + L ++ QS F+ Sbjct: 196 VRRFQAQLPQVSCVQSRFV 214 Score = 37.7 bits (86), Expect = 0.036 Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 8/105 (7%) Query: 589 SEKSDQETGRVLLFL-----SLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAG 643 S+ +D +VL FL SLS ++TD+GL + + G P LEHL LS C ++ G Sbjct: 86 SKLTDASLAKVLQFLQLRQLSLSLLPELTDNGL--VAVARGCPSLEHLALSHCSRLSDKG 143 Query: 644 LQDLVSACPSLNDEYFYYCDNINGPHADT-ASGCQNLQCGFRACC 687 S+ P L C + D C+ L+ A C Sbjct: 144 WAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATC 188 Score = 32.3 bits (72), Expect = 1.5 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 2/64 (3%) Query: 603 LSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYC 662 L+LS C +++D G P L+HLNLS C + L + AC L C Sbjct: 131 LALSHCSRLSDKGWA--QAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATC 188 Query: 663 DNIN 666 IN Sbjct: 189 PGIN 192 >gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo sapiens] Length = 424 Score = 37.0 bits (84), Expect = 0.061 Identities = 56/232 (24%), Positives = 87/232 (37%), Gaps = 37/232 (15%) Query: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHWARGDWYSGPATELD 267 LP E++L IFS L EL + S V +W +L SLW+ L T + Sbjct: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL-------------DLTGKN 146 Query: 268 TEPD--DEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVL 325 PD + R + + + + + +S + +E LHG++ Sbjct: 147 LHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCS 206 Query: 326 PYVGTSVKTLVLA----YSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWLGC 381 S++ L L+ + A +S +VR L C S F + L Sbjct: 207 KLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGF------------SEFALQTLLSS 254 Query: 382 CQSLRHLDLSGC----EKITDVALEKISRALGILTSHQSGFLKTSTSKITST 429 C L L+LS C EK VA+ +S + L + SG+ K ST Sbjct: 255 CSRLDELNLSWCFDFTEKHVQVAVAHVSETITQL--NLSGYRKNLQKSDLST 304 Score = 32.0 bits (71), Expect = 2.0 Identities = 16/46 (34%), Positives = 23/46 (50%) Query: 628 LEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADTA 673 L LNLSGC + LQ L+S+C L++ +C + H A Sbjct: 232 LVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVA 277 Score = 31.2 bits (69), Expect = 3.4 Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 5/106 (4%) Query: 327 YVGTSVKTLVLA-YSSAVSSKMVRQILELCPNLEHLDLTQT-DISDSAFDSWSWLGCCQS 384 +V ++ L L+ Y + + ++ CPNL HLDL+ + + + F + L Sbjct: 280 HVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQL---NY 336 Query: 385 LRHLDLSGCEKITDVALEKISRALGILTSHQSGFLKTSTSKITSTA 430 L+HL LS C I L ++ + T G + T ++ A Sbjct: 337 LQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPDGTLQLLKEA 382 >gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo sapiens] Length = 410 Score = 37.0 bits (84), Expect = 0.061 Identities = 56/232 (24%), Positives = 87/232 (37%), Gaps = 37/232 (15%) Query: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHWARGDWYSGPATELD 267 LP E++L IFS L EL + S V +W +L SLW+ L T + Sbjct: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL-------------DLTGKN 146 Query: 268 TEPD--DEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVL 325 PD + R + + + + + +S + +E LHG++ Sbjct: 147 LHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCS 206 Query: 326 PYVGTSVKTLVLA----YSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWLGC 381 S++ L L+ + A +S +VR L C S F + L Sbjct: 207 KLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGF------------SEFALQTLLSS 254 Query: 382 CQSLRHLDLSGC----EKITDVALEKISRALGILTSHQSGFLKTSTSKITST 429 C L L+LS C EK VA+ +S + L + SG+ K ST Sbjct: 255 CSRLDELNLSWCFDFTEKHVQVAVAHVSETITQL--NLSGYRKNLQKSDLST 304 Score = 32.0 bits (71), Expect = 2.0 Identities = 16/46 (34%), Positives = 23/46 (50%) Query: 628 LEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADTA 673 L LNLSGC + LQ L+S+C L++ +C + H A Sbjct: 232 LVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVA 277 Score = 32.0 bits (71), Expect = 2.0 Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 5/83 (6%) Query: 327 YVGTSVKTLVLA-YSSAVSSKMVRQILELCPNLEHLDLTQT-DISDSAFDSWSWLGCCQS 384 +V ++ L L+ Y + + ++ CPNL HLDL+ + + + F + L Sbjct: 280 HVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQL---NY 336 Query: 385 LRHLDLSGCEKITDVALEKISRA 407 L+HL LS C I L ++RA Sbjct: 337 LQHLSLSRCYDIIPETLLLVTRA 359 >gi|30520327 F-box protein 27 [Homo sapiens] Length = 283 Score = 36.6 bits (83), Expect = 0.080 Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 1/47 (2%) Query: 200 EHSTGITHLPPEVMLSIFSYLNPQELC-RCSQVSMKWSQLTKTGSLW 245 E + ++ LPPE++L + S++ P+ L RC QV W L +LW Sbjct: 21 EEALDLSQLPPELLLVVLSHVPPRTLLGRCRQVCRGWRALVDGQALW 67 >gi|190194416 F-box and leucine-rich repeat protein 15 [Homo sapiens] Length = 300 Score = 36.2 bits (82), Expect = 0.10 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 2/72 (2%) Query: 594 QETGRVLLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPS 653 Q G L LSL+ + D ++ L P L HL+L+GCL + G++ L CP Sbjct: 189 QRRGAGLRSLSLAVNANVGDAAVQ--ELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPV 246 Query: 654 LNDEYFYYCDNI 665 L +C ++ Sbjct: 247 LRSLRVRHCHHV 258 Score = 35.0 bits (79), Expect = 0.23 Identities = 36/159 (22%), Positives = 59/159 (37%), Gaps = 38/159 (23%) Query: 286 HEWDEDADIDE--SEESAEESIAIS-IAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSA 342 HEW D D+ + S+A+ Q+ +R L L ++ L LA+ Sbjct: 98 HEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGC-----PRLQRLSLAHCDW 152 Query: 343 VSSKMVRQILELCPNLEHLDLT----------------------------QTDISDSAFD 374 V +R + + CP LE LDLT ++ D+A Sbjct: 153 VDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQ 212 Query: 375 SWSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTS 413 + C L HLDL+GC ++ + ++ +L S Sbjct: 213 ELA--RNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRS 249 Score = 35.0 bits (79), Expect = 0.23 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 2/54 (3%) Query: 603 LSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLND 656 ++L GC Q++ L L G P L+ L+L+ C + G L+ L CP+L + Sbjct: 119 VALGGCGQLSRRALGALA--EGCPRLQRLSLAHCDWVDGLALRGLADRCPALEE 170 Score = 34.3 bits (77), Expect = 0.40 Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 1/78 (1%) Query: 329 GTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWLGCCQSLRHL 388 G +++L LA ++ V V+++ CP L HLDLT + + + C LR L Sbjct: 192 GAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGC-LRVGSDGVRTLAEYCPVLRSL 250 Query: 389 DLSGCEKITDVALEKISR 406 + C + + +L ++ + Sbjct: 251 RVRHCHHVAESSLSRLRK 268 >gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens] Length = 479 Score = 36.2 bits (82), Expect = 0.10 Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 15/74 (20%) Query: 603 LSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDL-----------VSAC 651 L L C++IT+HG V+ + LP L L+LSGC +T G++ + +S C Sbjct: 299 LRLLSCWEITNHG--VVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWC 356 Query: 652 PSLNDEYFYY--CD 663 P + D Y CD Sbjct: 357 PRITDMALEYVACD 370 Score = 33.5 bits (75), Expect = 0.68 Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 3/78 (3%) Query: 329 GTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQ-TDISDSAFDSWSWLGCCQSLRH 387 G S TL L +++ V ++ PNL L L+ + ++D + + + LR Sbjct: 293 GHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVA--ENLRKLRS 350 Query: 388 LDLSGCEKITDVALEKIS 405 LDLS C +ITD+ALE ++ Sbjct: 351 LDLSWCPRITDMALEYVA 368 Score = 33.1 bits (74), Expect = 0.88 Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 3/90 (3%) Query: 600 LLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYF 659 L LSLSGC ++TD G+ + + L L L+LS C IT L+ + L + Sbjct: 322 LTALSLSGCSKVTDDGVEL--VAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELVL 379 Query: 660 YYCDNINGPHADTASGCQNLQCGF-RACCR 688 C I S +L+ + R CC+ Sbjct: 380 DRCVRITDTGLSYLSTMSSLRSLYLRWCCQ 409 Score = 31.6 bits (70), Expect = 2.6 Identities = 57/257 (22%), Positives = 94/257 (36%), Gaps = 60/257 (23%) Query: 211 EVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHWARGDWYSGPATELDTEP 270 +++ +F Y + E C +QV W ++ W L PV A+ + P E Sbjct: 100 KILNGLFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGE----- 154 Query: 271 DDEWVKNRKDESRAFHEWD----EDADIDESEESAEES-----------IAISIAQMEKR 315 E+V + +R F + D DI E ++ S I+ A +E Sbjct: 155 -KEFVNLQGFAARGFEGFCLVGVSDLDICEFIDNYALSKKGVKAMSLKRSTITDAGLEVM 213 Query: 316 L--LHGLIHNVLP----------YVGTSVKTLVLAYSSA--VSSKMVRQILELCPNLEHL 361 L + G++ L + S + L+ S V+ + I +L PNL L Sbjct: 214 LEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAEL 273 Query: 362 DLTQTDISDSAFDSWS-----------WLGCCQSLRH--------------LDLSGCEKI 396 L ++D+A ++ L C + H L LSGC K+ Sbjct: 274 SLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKV 333 Query: 397 TDVALEKISRALGILTS 413 TD +E ++ L L S Sbjct: 334 TDDGVELVAENLRKLRS 350 >gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapiens] Length = 694 Score = 35.8 bits (81), Expect = 0.14 Identities = 15/41 (36%), Positives = 21/41 (51%) Query: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHL 248 LP L +F +L P+ELC C +V WS+ LW + Sbjct: 424 LPRAAWLRVFQHLGPRELCICMRVCRTWSRWCYDKRLWPRM 464 Score = 31.2 bits (69), Expect = 3.4 Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 3/53 (5%) Query: 600 LLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACP 652 L+ L+L+GC+++TDH L L P L L+L C ++ L +A P Sbjct: 629 LVHLNLAGCHRLTDH---CLPLFRRCPRLRRLDLRSCRQLSPEACARLAAAGP 678 >gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [Homo sapiens] Length = 1336 Score = 35.4 bits (80), Expect = 0.18 Identities = 14/38 (36%), Positives = 23/38 (60%) Query: 211 EVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHL 248 EV +++FSYL+ Q+LC C +V W++ LW + Sbjct: 1068 EVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRI 1105 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.132 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,651,054 Number of Sequences: 37866 Number of extensions: 1179009 Number of successful extensions: 4476 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 56 Number of HSP's successfully gapped in prelim test: 75 Number of HSP's that attempted gapping in prelim test: 4176 Number of HSP's gapped (non-prelim): 322 length of query: 691 length of database: 18,247,518 effective HSP length: 109 effective length of query: 582 effective length of database: 14,120,124 effective search space: 8217912168 effective search space used: 8217912168 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.