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Search of human proteins with 16306552
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16306552 semaphorin Y [Homo sapiens]
(930 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16306552 semaphorin Y [Homo sapiens] 1912 0.0
gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens] 633 0.0
gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens] 633 0.0
gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens] 632 0.0
gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens] 586 e-167
gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens] 583 e-166
gi|11991660 sema domain, transmembrane domain (TM), and cytoplas... 561 e-160
gi|19718780 semaphorin 6B precursor [Homo sapiens] 550 e-156
gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens] 503 e-142
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 283 7e-76
gi|5174673 semaphorin 3A precursor [Homo sapiens] 279 1e-74
gi|147904700 semaphorin 5A [Homo sapiens] 277 3e-74
gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens] 276 8e-74
gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens] 271 2e-72
gi|41406086 semaphorin 3D [Homo sapiens] 266 5e-71
gi|157388902 semaphorin 4C [Homo sapiens] 261 2e-69
gi|6912650 semaphorin 3E [Homo sapiens] 258 1e-68
gi|39777610 semaphorin 4B precursor [Homo sapiens] 246 9e-65
gi|39777608 semaphorin 4B precursor [Homo sapiens] 246 9e-65
gi|188497703 semaphorin 3F [Homo sapiens] 241 2e-63
gi|214010220 semaphorin 4D isoform 2 [Homo sapiens] 234 3e-61
gi|214010218 semaphorin 4D isoform 1 [Homo sapiens] 234 3e-61
gi|9910362 semaphorin sem2 [Homo sapiens] 232 1e-60
gi|5454048 semaphorin 3C [Homo sapiens] 226 1e-58
gi|21361914 semaphorin B [Homo sapiens] 218 3e-56
gi|19923279 semaphorin W [Homo sapiens] 214 3e-55
gi|28872814 semaphorin 4G [Homo sapiens] 205 2e-52
gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens] 131 3e-30
gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens] 131 3e-30
gi|225637524 semaphorin 7A isoform 3 [Homo sapiens] 113 9e-25
>gi|16306552 semaphorin Y [Homo sapiens]
Length = 930
Score = 1912 bits (4953), Expect = 0.0
Identities = 930/930 (100%), Positives = 930/930 (100%)
Query: 1 MPRAPHFMPLLLLLLLLSLPHTQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAELG 60
MPRAPHFMPLLLLLLLLSLPHTQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAELG
Sbjct: 1 MPRAPHFMPLLLLLLLLSLPHTQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAELG 60
Query: 61 LDFQRFLTLNRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQDVENCAVRGKLTDE 120
LDFQRFLTLNRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQDVENCAVRGKLTDE
Sbjct: 61 LDFQRFLTLNRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQDVENCAVRGKLTDE 120
Query: 121 CYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAI 180
CYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAI
Sbjct: 121 CYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAI 180
Query: 181 FAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDHVYFFF 240
FAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDHVYFFF
Sbjct: 181 FAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDHVYFFF 240
Query: 241 REVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVL 300
REVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVL
Sbjct: 241 REVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVL 300
Query: 301 QALTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPV 360
QALTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPV
Sbjct: 301 QALTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPV 360
Query: 361 SEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLTLTSR 420
SEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLTLTSR
Sbjct: 361 SEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLTLTSR 420
Query: 421 ALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEIDAYSPARCS 480
ALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEIDAYSPARCS
Sbjct: 421 ALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEIDAYSPARCS 480
Query: 481 GKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGWH 540
GKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGWH
Sbjct: 481 GKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGWH 540
Query: 541 SSRGCVDIRGSGGTDVDQAGNQESMEHGDCQDGATGSQSGPGDSAYGVRRDLPPASASRS 600
SSRGCVDIRGSGGTDVDQAGNQESMEHGDCQDGATGSQSGPGDSAYGVRRDLPPASASRS
Sbjct: 541 SSRGCVDIRGSGGTDVDQAGNQESMEHGDCQDGATGSQSGPGDSAYGVRRDLPPASASRS 600
Query: 601 VPIPLLLASVAAAFALGASVSGLLVSCACRRAHRRRGKDIETPGLPRPLSLRSLARLHGG 660
VPIPLLLASVAAAFALGASVSGLLVSCACRRAHRRRGKDIETPGLPRPLSLRSLARLHGG
Sbjct: 601 VPIPLLLASVAAAFALGASVSGLLVSCACRRAHRRRGKDIETPGLPRPLSLRSLARLHGG 660
Query: 661 GPEPPPPSKDGDAVQTPQLYTTFLPPPEGVPPPELACLPTPESTPELPVKHLRAAGDPWE 720
GPEPPPPSKDGDAVQTPQLYTTFLPPPEGVPPPELACLPTPESTPELPVKHLRAAGDPWE
Sbjct: 661 GPEPPPPSKDGDAVQTPQLYTTFLPPPEGVPPPELACLPTPESTPELPVKHLRAAGDPWE 720
Query: 721 WNQNRNNAKEGPGRSRGGHAAGGPAPRVLVRPPPPGCPGQAVEVTTLEELLRYLHGPQPP 780
WNQNRNNAKEGPGRSRGGHAAGGPAPRVLVRPPPPGCPGQAVEVTTLEELLRYLHGPQPP
Sbjct: 721 WNQNRNNAKEGPGRSRGGHAAGGPAPRVLVRPPPPGCPGQAVEVTTLEELLRYLHGPQPP 780
Query: 781 RKGAEPPAPLTSRALPPEPAPALLGGPSPRPHECASPLRLDVPPEGRCASAPARPALSAP 840
RKGAEPPAPLTSRALPPEPAPALLGGPSPRPHECASPLRLDVPPEGRCASAPARPALSAP
Sbjct: 781 RKGAEPPAPLTSRALPPEPAPALLGGPSPRPHECASPLRLDVPPEGRCASAPARPALSAP 840
Query: 841 APRLGVGGGRRLPFSGHRAPPALLTRVPSGGPSRYSGGPGKHLLYLGRPEGYRGRALKRV 900
APRLGVGGGRRLPFSGHRAPPALLTRVPSGGPSRYSGGPGKHLLYLGRPEGYRGRALKRV
Sbjct: 841 APRLGVGGGRRLPFSGHRAPPALLTRVPSGGPSRYSGGPGKHLLYLGRPEGYRGRALKRV 900
Query: 901 DVEKPQLSLKPPLVGPSSRQAVPNGGRFNF 930
DVEKPQLSLKPPLVGPSSRQAVPNGGRFNF
Sbjct: 901 DVEKPQLSLKPPLVGPSSRQAVPNGGRFNF 930
>gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]
Length = 1011
Score = 633 bits (1632), Expect = 0.0
Identities = 351/774 (45%), Positives = 482/774 (62%), Gaps = 43/774 (5%)
Query: 7 FMPLLLLLLLLSLPHTQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAELGLDFQRF 66
F+ +LLL+ +FP+D PL D + FRG ++ LDFQ
Sbjct: 4 FLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRG-RPSGNESQHRLDFQLM 62
Query: 67 LTLNRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRS--QDVENCAVRGKLTDECYNY 124
L + TL +A RD V++ +L + E ++PNK LTWRS QD ENCA++GK DEC+N+
Sbjct: 63 LKIRDTLYIAGRDQVYTVNLNEMPKTE-VIPNKKLTWRSRQQDRENCAMKGKHKDECHNF 121
Query: 125 IRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAIFAEG 184
I+V VP + + + CGTN+F+P+CR Y +++L+ +GEE+SG ARCPFDA Q+NVA+FA+G
Sbjct: 122 IKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADG 181
Query: 185 SLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDHVYFFFREVS 244
LYSAT ADF ASDAV+YRS+G LR+ KYDSKW++EPHF+ A+E+G++VYFFFRE++
Sbjct: 182 KLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIA 241
Query: 245 VEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALT 304
VE LG+ +SRVAR+CK DMGGS R L++HWTSFLK RLNCSVPGDS FYFDVLQ++T
Sbjct: 242 VEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSIT 301
Query: 305 GPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPVSEDR 364
+ ++G + GVFTTQ NSIPGSAVCAF +D+IE+ F+G+FKEQ++ D WT V ED+
Sbjct: 302 DIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDK 361
Query: 365 VPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLTLTS-RALL 423
VP PRPG CA G A + +S D PD+ L+FIK+HPL+D AVPP+ +P T T R L
Sbjct: 362 VPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRL 421
Query: 424 TQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEIDAYSPARCSGKR 483
T ++VD AGP+ N TV+F+GS G VLKVL + +LLEEI+AY+ A+CS +
Sbjct: 422 TAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAEN 481
Query: 484 TAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGWHSSR 543
+ +++I L+LD + H L+VAFS CI+ +PLSRC R+G+C++SC+AS+DPYCGW S
Sbjct: 482 --EEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQG 539
Query: 544 GCVDIR-GSGGTDVDQAGNQESMEHGDCQDGATGSQSGPGDSAYGVRRDLPPASASRSVP 602
C + G D G QD G+ + GD +GVR ++ +++ V
Sbjct: 540 SCGRVTPGMLLLTEDFFAFHNHSAEGYEQDTEFGNTAHLGD-CHGVRWEVQSGESNQMVH 598
Query: 603 IPLLLASVAAAFALGASVSGLLVSC---ACRRAHRRRGKDIETPGLPRPLSLRSLARLHG 659
+ +L+ V AAF LGA ++G+ V C R +R+ KD E+ S S A+L+G
Sbjct: 599 MNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTD-SSGSFAKLNG 657
Query: 660 GGPEPPPPSKDGDAVQTPQLYTTFLP-----PPEG----------VPPPELACLPTPEST 704
P + + +P+LY+ L PP G PPELA LPTPEST
Sbjct: 658 LFDSPVKEYQQN--IDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPEST 715
Query: 705 PELPVKHLRAAGDPWEWNQNRNNAKEGPGRSRGGHAAGGPAPRVLVRPPPPGCP 758
P L K L+A K ++ G A+ P+ PPP P
Sbjct: 716 PVLHQKTLQA-------------MKSHSEKAHGHGASRKETPQFFPSSPPPHSP 756
>gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]
Length = 1017
Score = 633 bits (1632), Expect = 0.0
Identities = 351/781 (44%), Positives = 482/781 (61%), Gaps = 51/781 (6%)
Query: 7 FMPLLLLLLLLSLPHTQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAELGLDFQRF 66
F+ +LLL+ +FP+D PL D + FRG ++ LDFQ
Sbjct: 4 FLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRG-RPSGNESQHRLDFQLM 62
Query: 67 LTLNRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRS--QDVENCAVRGKLTDECYNY 124
L + TL +A RD V++ +L + E ++PNK LTWRS QD ENCA++GK DEC+N+
Sbjct: 63 LKIRDTLYIAGRDQVYTVNLNEMPKTE-VIPNKKLTWRSRQQDRENCAMKGKHKDECHNF 121
Query: 125 IRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAIFAEG 184
I+V VP + + + CGTN+F+P+CR Y +++L+ +GEE+SG ARCPFDA Q+NVA+FA+G
Sbjct: 122 IKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADG 181
Query: 185 SLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDHVYFFFREVS 244
LYSAT ADF ASDAV+YRS+G LR+ KYDSKW++EPHF+ A+E+G++VYFFFRE++
Sbjct: 182 KLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIA 241
Query: 245 VEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALT 304
VE LG+ +SRVAR+CK DMGGS R L++HWTSFLK RLNCSVPGDS FYFDVLQ++T
Sbjct: 242 VEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSIT 301
Query: 305 GPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPVSEDR 364
+ ++G + GVFTTQ NSIPGSAVCAF +D+IE+ F+G+FKEQ++ D WT V ED+
Sbjct: 302 DIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDK 361
Query: 365 VPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLTLTS-RALL 423
VP PRPG CA G A + +S D PD+ L+FIK+HPL+D AVPP+ +P T T R L
Sbjct: 362 VPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRL 421
Query: 424 TQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEIDAYSPARCSGKR 483
T ++VD AGP+ N TV+F+GS G VLKVL + +LLEEI+AY+ A+CS +
Sbjct: 422 TAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAEN 481
Query: 484 TAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGWHSSR 543
+ +++I L+LD + H L+VAFS CI+ +PLSRC R+G+C++SC+AS+DPYCGW S
Sbjct: 482 --EEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQG 539
Query: 544 GCVDIR----GSGGTDVDQAGNQESMEHGDCQD----GATGSQSGPGDSAYGVRRDLPPA 595
C + G + GN + GDC + T G GVR ++
Sbjct: 540 SCGRVTPGMLAEGYEQDTEFGNTAHL--GDCHEILPTSTTPDYKIFGGPTSGVRWEVQSG 597
Query: 596 SASRSVPIPLLLASVAAAFALGASVSGLLVSC---ACRRAHRRRGKDIETPGLPRPLSLR 652
+++ V + +L+ V AAF LGA ++G+ V C R +R+ KD E+ S
Sbjct: 598 ESNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTD-SSG 656
Query: 653 SLARLHGGGPEPPPPSKDGDAVQTPQLYTTFLP-----PPEG----------VPPPELAC 697
S A+L+G P + + +P+LY+ L PP G PPELA
Sbjct: 657 SFAKLNGLFDSPVKEYQQN--IDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAA 714
Query: 698 LPTPESTPELPVKHLRAAGDPWEWNQNRNNAKEGPGRSRGGHAAGGPAPRVLVRPPPPGC 757
LPTPESTP L K L+A K ++ G A+ P+ PPP
Sbjct: 715 LPTPESTPVLHQKTLQA-------------MKSHSEKAHGHGASRKETPQFFPSSPPPHS 761
Query: 758 P 758
P
Sbjct: 762 P 762
>gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]
Length = 998
Score = 632 bits (1631), Expect = 0.0
Identities = 349/773 (45%), Positives = 481/773 (62%), Gaps = 54/773 (6%)
Query: 7 FMPLLLLLLLLSLPHTQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAELGLDFQRF 66
F+ +LLL+ +FP+D PL D + FRG ++ LDFQ
Sbjct: 4 FLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRG-RPSGNESQHRLDFQLM 62
Query: 67 LTLNRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRS--QDVENCAVRGKLTDECYNY 124
L + TL +A RD V++ +L + E ++PNK LTWRS QD ENCA++GK DEC+N+
Sbjct: 63 LKIRDTLYIAGRDQVYTVNLNEMPKTE-VIPNKKLTWRSRQQDRENCAMKGKHKDECHNF 121
Query: 125 IRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAIFAEG 184
I+V VP + + + CGTN+F+P+CR Y +++L+ +GEE+SG ARCPFDA Q+NVA+FA+G
Sbjct: 122 IKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADG 181
Query: 185 SLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDHVYFFFREVS 244
LYSAT ADF ASDAV+YRS+G LR+ KYDSKW++EPHF+ A+E+G++VYFFFRE++
Sbjct: 182 KLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIA 241
Query: 245 VEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALT 304
VE LG+ +SRVAR+CK DMGGS R L++HWTSFLK RLNCSVPGDS FYFDVLQ++T
Sbjct: 242 VEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSIT 301
Query: 305 GPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPVSEDR 364
+ ++G + GVFTTQ NSIPGSAVCAF +D+IE+ F+G+FKEQ++ D WT V ED+
Sbjct: 302 DIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDK 361
Query: 365 VPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLTLTS-RALL 423
VP PRPG CA G A + +S D PD+ L+FIK+HPL+D AVPP+ +P T T R L
Sbjct: 362 VPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRL 421
Query: 424 TQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEIDAYSPARCSGKR 483
T ++VD AGP+ N TV+F+GS G VLKVL + +LLEEI+AY+ A+CS +
Sbjct: 422 TAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAEN 481
Query: 484 TAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGWHSSR 543
+ +++I L+LD + H L+VAFS CI+ +PLSRC R+G+C++SC+AS+DPYCGW S
Sbjct: 482 --EEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQG 539
Query: 544 GCVDIRGSGGTDVDQAGNQESMEHGDCQDGATGSQSGPGDSAYGVRRDLPPASASRSVPI 603
C + + G QD G+ + GD +GVR ++ +++ V +
Sbjct: 540 SCGRV------------TPGMLAEGYEQDTEFGNTAHLGD-CHGVRWEVQSGESNQMVHM 586
Query: 604 PLLLASVAAAFALGASVSGLLVSC---ACRRAHRRRGKDIETPGLPRPLSLRSLARLHGG 660
+L+ V AAF LGA ++G+ V C R +R+ KD E+ S S A+L+G
Sbjct: 587 NVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTD-SSGSFAKLNGL 645
Query: 661 GPEPPPPSKDGDAVQTPQLYTTFLP-----PPEG----------VPPPELACLPTPESTP 705
P + + +P+LY+ L PP G PPELA LPTPESTP
Sbjct: 646 FDSPVKEYQQN--IDSPKLYSNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPESTP 703
Query: 706 ELPVKHLRAAGDPWEWNQNRNNAKEGPGRSRGGHAAGGPAPRVLVRPPPPGCP 758
L K L+A K ++ G A+ P+ PPP P
Sbjct: 704 VLHQKTLQA-------------MKSHSEKAHGHGASRKETPQFFPSSPPPHSP 743
>gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]
Length = 597
Score = 586 bits (1510), Expect = e-167
Identities = 294/580 (50%), Positives = 398/580 (68%), Gaps = 13/580 (2%)
Query: 7 FMPLLLLLLLLSLPHTQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAELGLDFQRF 66
F+ +LLL+ +FP+D PL D + FRG ++ LDFQ
Sbjct: 4 FLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRG-RPSGNESQHRLDFQLM 62
Query: 67 LTLNRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRS--QDVENCAVRGKLTDECYNY 124
L + TL +A RD V++ +L + E ++PNK LTWRS QD ENCA++GK DEC+N+
Sbjct: 63 LKIRDTLYIAGRDQVYTVNLNEMPKTE-VIPNKKLTWRSRQQDRENCAMKGKHKDECHNF 121
Query: 125 IRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAIFAEG 184
I+V VP + + + CGTN+F+P+CR Y +++L+ +GEE+SG ARCPFDA Q+NVA+FA+G
Sbjct: 122 IKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADG 181
Query: 185 SLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDHVYFFFREVS 244
LYSAT ADF ASDAV+YRS+G LR+ KYDSKW++EPHF+ A+E+G++VYFFFRE++
Sbjct: 182 KLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIA 241
Query: 245 VEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALT 304
VE LG+ +SRVAR+CK DMGGS R L++HWTSFLK RLNCSVPGDS FYFDVLQ++T
Sbjct: 242 VEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSIT 301
Query: 305 GPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPVSEDR 364
+ ++G + GVFTTQ NSIPGSAVCAF +D+IE+ F+G+FKEQ++ D WT V ED+
Sbjct: 302 DIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDK 361
Query: 365 VPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLTLTS-RALL 423
VP PRPG CA G A + +S D PD+ L+FIK+HPL+D AVPP+ +P T T R L
Sbjct: 362 VPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRL 421
Query: 424 TQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEIDAYSPARCSGKR 483
T ++VD AGP+ N TV+F+GS G VLKVL + +LLEEI+AY+ A+CS +
Sbjct: 422 TAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAEN 481
Query: 484 TAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGWHSSR 543
+ +++I L+LD + H L+VAFS CI+ +PLSRC R+G+C++SC+AS+DPYCGW S
Sbjct: 482 --EEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQG 539
Query: 544 GCVDIR----GSGGTDVDQAGNQESMEHGDCQDGATGSQS 579
C + G + GN + GDC D S S
Sbjct: 540 SCGRVTPGMLAEGYEQDTEFGNTAHL--GDCHDMEVSSSS 577
>gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]
Length = 1073
Score = 583 bits (1502), Expect = e-166
Identities = 291/573 (50%), Positives = 396/573 (69%), Gaps = 13/573 (2%)
Query: 7 FMPLLLLLLLLSLPHTQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAELGLDFQRF 66
F+ +LLL+ +FP+D PL D + FRG ++ LDFQ
Sbjct: 4 FLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRG-RPSGNESQHRLDFQLM 62
Query: 67 LTLNRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRS--QDVENCAVRGKLTDECYNY 124
L + TL +A RD V++ +L + E ++PNK LTWRS QD ENCA++GK DEC+N+
Sbjct: 63 LKIRDTLYIAGRDQVYTVNLNEMPKTE-VIPNKKLTWRSRQQDRENCAMKGKHKDECHNF 121
Query: 125 IRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAIFAEG 184
I+V VP + + + CGTN+F+P+CR Y +++L+ +GEE+SG ARCPFDA Q+NVA+FA+G
Sbjct: 122 IKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADG 181
Query: 185 SLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDHVYFFFREVS 244
LYSAT ADF ASDAV+YRS+G LR+ KYDSKW++EPHF+ A+E+G++VYFFFRE++
Sbjct: 182 KLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIA 241
Query: 245 VEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALT 304
VE LG+ +SRVAR+CK DMGGS R L++HWTSFLK RLNCSVPGDS FYFDVLQ++T
Sbjct: 242 VEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSIT 301
Query: 305 GPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPVSEDR 364
+ ++G + GVFTTQ NSIPGSAVCAF +D+IE+ F+G+FKEQ++ D WT V ED+
Sbjct: 302 DIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDK 361
Query: 365 VPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLTLTS-RALL 423
VP PRPG CA G A + +S D PD+ L+FIK+HPL+D AVPP+ +P T T R L
Sbjct: 362 VPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRL 421
Query: 424 TQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEIDAYSPARCSGKR 483
T ++VD AGP+ N TV+F+GS G VLKVL + +LLEEI+AY+ A+CS +
Sbjct: 422 TAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAEN 481
Query: 484 TAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGWHSSR 543
+ +++I L+LD + H L+VAFS CI+ +PLSRC R+G+C++SC+AS+DPYCGW S
Sbjct: 482 --EEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQG 539
Query: 544 GCVDIR----GSGGTDVDQAGNQESMEHGDCQD 572
C + G + GN + GDC +
Sbjct: 540 SCGRVTPGMLAEGYEQDTEFGNTAHL--GDCHE 570
Score = 62.0 bits (149), Expect = 2e-09
Identities = 58/190 (30%), Positives = 84/190 (44%), Gaps = 34/190 (17%)
Query: 587 GVRRDLPPASASRSVPIPLLLASVAAAFALGASVSGLLVSC---ACRRAHRRRGKDIETP 643
GVR ++ +++ V + +L+ V AAF LGA ++G+ V C R +R+ KD E+
Sbjct: 645 GVRWEVQSGESNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESA 704
Query: 644 GLPRPLSLRSLARLHGGGPEPPPPSKDGDAVQTPQLYTTFLP-----PPEGVP------- 691
S S A+L+G P + + +P+LY+ L PP G
Sbjct: 705 QSCTDSS-GSFAKLNGLFDSPVKEYQQN--IDSPKLYSNLLTSRKELPPNGDTKSMVMDH 761
Query: 692 ---PPELACLPTPESTPELPVKHLRAAGDPWEWNQNRNNAKEGPGRSRGGHAAGGPAPRV 748
PPELA LPTPESTP L K L+A K ++ G A+ P+
Sbjct: 762 RGQPPELAALPTPESTPVLHQKTLQA-------------MKSHSEKAHGHGASRKETPQF 808
Query: 749 LVRPPPPGCP 758
PPP P
Sbjct: 809 FPSSPPPHSP 818
>gi|11991660 sema domain, transmembrane domain (TM), and cytoplasmic
domain, (semaphorin) 6A [Homo sapiens]
Length = 1030
Score = 561 bits (1447), Expect = e-160
Identities = 324/789 (41%), Positives = 448/789 (56%), Gaps = 81/789 (10%)
Query: 13 LLLLLSLPH-TQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAEL-GLDFQRFLTLN 70
LLL +L H A FP+D P+ IS T F G + + LD Q + +N
Sbjct: 6 LLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQMIMIMN 65
Query: 71 RTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQ--DVENCAVRGKLTDECYNYIRVL 128
TL +AARDH+++ D+ E + +K LTW+S+ DV+ C ++GK DEC+N+I+VL
Sbjct: 66 GTLYIAARDHIYTVDIDTSHT-EEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIKVL 124
Query: 129 VPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAIFAEGSLYS 188
+ + L CGTN+F+P CR+Y + +L+ G+E SG ARCP+DA +NVA+FA+G LYS
Sbjct: 125 LKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADGKLYS 184
Query: 189 ATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDHVYFFFREVSVEDA 248
AT DF A DAV+YRSLG P LR+ K+DSKWL+EP+FVQA+++GD++YFFFRE++VE
Sbjct: 185 ATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYN 244
Query: 249 RLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALTGPVN 308
+G+V F RVA+VCK DMGGS R L++ WTSFLK RLNCSVPGDS FYF++LQA+T +
Sbjct: 245 TMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIR 304
Query: 309 LHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPVSEDRVPSP 368
++GR + F+T NSIPGSAVCA+ + +I F G+FKEQ+S D WTPV ++RVP P
Sbjct: 305 INGRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKP 364
Query: 369 RPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQP-LLTLTSRALLTQVA 427
RPG CAG +++S + PDD L FIK HPL+D AVP + ++P L R LT++A
Sbjct: 365 RPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIA 424
Query: 428 VDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGG-PEPILLEEIDAYSPARCSGKRTAQ 486
VD AGP+ N TV+FLGS G +LK L G SG + + LEE+ Y+ +CS
Sbjct: 425 VDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSEKCSYDGVED 484
Query: 487 TARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGWHSSRG-C 545
+RI+G++LD L+VAFS C++ +PL RC RHG C+++C+AS+DPYCGW G C
Sbjct: 485 --KRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGGAC 542
Query: 546 VDIRGSGGTDVDQ---AGNQESMEHGDCQDG-------------ATGSQSGPGDSAY--- 586
+ + +Q GN + + GDC + +T + Y
Sbjct: 543 SHLSPNSRLTFEQDIERGNTDGL--GDCHNSFVALNGHSSSLLPSTTTSDSTAQEGYESR 600
Query: 587 -------------------------------GVRRDLPPASASRSVPIPLLLASVAAAFA 615
GV R+ + VP+ LL +V AF
Sbjct: 601 GGMLDWKHLLDSPDSTDPLGAVSSHNHQDKKGVIRESYLKGHDQLVPVTLLAIAVILAFV 660
Query: 616 LGASVSGLLVSCACRRAHRRRG------KDIETPGLPRPLSLRSLARLHGGGPEPPPPSK 669
+GA SG+ V C C HRR+ K+ E R S+ S+ +L G +
Sbjct: 661 MGAVFSGITVYCVC--DHRRKDVAVVQRKEKELTHSRRG-SMSSVTKLSGLFGDTQSKDP 717
Query: 670 DGDAVQTPQLYTTFLPPPEGVPPP---------ELACLPTPESTPELPVKHLRAAGD-PW 719
+A+ TP ++ L P +L LPTPESTP L K + G W
Sbjct: 718 KPEAILTPLMHNGKLATPGNTAKMLIKADQHHLDLTALPTPESTPTLQQKRKPSRGSREW 777
Query: 720 EWNQNRNNA 728
E NQN NA
Sbjct: 778 ERNQNLINA 786
>gi|19718780 semaphorin 6B precursor [Homo sapiens]
Length = 888
Score = 550 bits (1416), Expect = e-156
Identities = 363/894 (40%), Positives = 471/894 (52%), Gaps = 81/894 (9%)
Query: 2 PRAPHFMPLLLLLLLLSLPHTQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAELGL 61
PRA P LLLLLLL L FP++P PL ++ + F G + G
Sbjct: 4 PRASPPRPALLLLLLL-LGGAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAEGA 62
Query: 62 D---FQRFLTLNRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQ--DVENCAVRGK 116
D QR L +NRTL + RD+++ +L+ E L + LTWRS D+ C ++GK
Sbjct: 63 DDLNIQRVLRVNRTLFIGDRDNLYRVELEPPTSTE-LRYQRKLTWRSNPSDINVCRMKGK 121
Query: 117 LTDECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQS 176
EC N+++VL+ D TL CG+N+F+PVC +Y I +LQ G+ +SG ARCP+D +
Sbjct: 122 QEGECRNFVKVLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKHA 181
Query: 177 NVAIFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDHV 236
NVA+F++G L++AT DF A DAV+YRSLG +P LR+ K+DSKW +EP+FV A+E G HV
Sbjct: 182 NVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHV 241
Query: 237 YFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFY 296
YFFFRE+++E L +V SRVARVCK D+GGSPR L++ WTSFLK RLNCSVPGDS FY
Sbjct: 242 YFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFY 301
Query: 297 FDVLQALTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGA 356
F+VLQA+TG V+L GR + VF+T +NSIPGSAVCAF L ++ FEG+F+EQ+S +
Sbjct: 302 FNVLQAVTGVVSLGGRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESI 361
Query: 357 WTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQP-LL 415
WTPV ED+VP PRPG CA G +++S LPDD+L F+K HPL+D AVP + H P +L
Sbjct: 362 WTPVPEDQVPRPRPGCCAAPG--MQYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWIL 419
Query: 416 TLTSRALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLT-PGGRSGGPE--PILLEEID 472
R LT+VAVD AGP N TV+FLGS GTVLK L P + G + LEE +
Sbjct: 420 RTLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFE 479
Query: 473 AYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLAS 532
Y P RC +T +R++ LELD L AF C+V +P++RC ++ C ++C+ S
Sbjct: 480 TYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGS 539
Query: 533 QDPYCGWHSSRGCVDIRGSGGTDVDQAGNQESMEHGDCQDGATGSQSGPGDSAYGVRRDL 592
QDPYCGW C+ + G + + E QD + S SG GD +R L
Sbjct: 540 QDPYCGWAPDGSCIFL---------SPGTRAAFE----QDVSGASTSGLGDCTGLLRASL 586
Query: 593 PPASASRSVPIPLLLASVAAAFALGASVSGLLVSCACRRAHRR---RGKDIET-PGLPRP 648
A V + LL+ S AAF +GA VSG V RR R KD E
Sbjct: 587 SEDRAG-LVSVNLLVTSSVAAFVVGAVVSGFSVGWFVGLRERRELARRKDKEAILAHGAG 645
Query: 649 LSLRSLARL--------------HGGGPEPPPPSKDGDAVQTPQLYTTFLPPPEGVPPP- 693
++ S++RL GGG PP + +Q T L +G P
Sbjct: 646 EAVLSVSRLGERRAQGPGGRGGGGGGGAGVPPEALLAPLMQNGWAKATLL---QGGPHDL 702
Query: 694 ELACLPTPESTPELPVKHLRAAGDPWEWNQNRNNAKEGPGRSRGGHAAGGPAPRVLVRPP 753
+ LPTPE TP LP K L P HA G PR
Sbjct: 703 DSGLLPTPEQTP-LPQKRL-------------------PTPHPHPHALG---PRAW---- 735
Query: 754 PPGCPGQAVEVTTLEELLRYLHGP-QPPRKGAEPPAPLTSRALPPEPAPALLGGPSPRPH 812
G P ++ LL P QPP G P R P A G PH
Sbjct: 736 DHGHPLLPASASSSLLLLAPARAPEQPPAPGEPTP---DGRLYAARPGRASHGDFPLTPH 792
Query: 813 ECASPLRLDVPPEGRCASAPARPALSAPAPRLGVGGGRRLPFSGHRAPPALLTR 866
R+ P G A A L P G RR P H P A L R
Sbjct: 793 ASPDRRRVVSAPTGPLDPASAADGLPRPWSPPPTGSLRR-PLGPHAPPAATLRR 845
>gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens]
Length = 476
Score = 503 bits (1295), Expect = e-142
Identities = 251/475 (52%), Positives = 336/475 (70%), Gaps = 5/475 (1%)
Query: 7 FMPLLLLLLLLSLPHTQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAELGLDFQRF 66
F+ +LLL+ +FP+D PL D + FRG ++ LDFQ
Sbjct: 4 FLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRG-RPSGNESQHRLDFQLM 62
Query: 67 LTLNRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRS--QDVENCAVRGKLTDECYNY 124
L + TL +A RD V++ +L + E ++PNK LTWRS QD ENCA++GK DEC+N+
Sbjct: 63 LKIRDTLYIAGRDQVYTVNLNEMPKTE-VIPNKKLTWRSRQQDRENCAMKGKHKDECHNF 121
Query: 125 IRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAIFAEG 184
I+V VP + + + CGTN+F+P+CR Y +++L+ +GEE+SG ARCPFDA Q+NVA+FA+G
Sbjct: 122 IKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADG 181
Query: 185 SLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDHVYFFFREVS 244
LYSAT ADF ASDAV+YRS+G LR+ KYDSKW++EPHF+ A+E+G++VYFFFRE++
Sbjct: 182 KLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIA 241
Query: 245 VEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALT 304
VE LG+ +SRVAR+CK DMGGS R L++HWTSFLK RLNCSVPGDS FYFDVLQ++T
Sbjct: 242 VEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSIT 301
Query: 305 GPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPVSEDR 364
+ ++G + GVFTTQ NSIPGSAVCAF +D+IE+ F+G+FKEQ++ D WT V ED+
Sbjct: 302 DIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDK 361
Query: 365 VPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLTLTS-RALL 423
VP PRPG CA G A + +S D PD+ L+FIK+HPL+D AVPP+ +P T T R L
Sbjct: 362 VPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRL 421
Query: 424 TQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEIDAYSPAR 478
T ++VD AGP+ N TV+F+GS G VLKVL + +LLEEI+AY+ A+
Sbjct: 422 TAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAK 476
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 283 bits (723), Expect = 7e-76
Identities = 180/476 (37%), Positives = 263/476 (55%), Gaps = 47/476 (9%)
Query: 73 LLVAARDHVFSFDL------QAEEEGEGLVPNKYLTWRSQDV--ENCAVRGKLTDECYNY 124
L+V AR+++F L QA E W S + +C +GK +EC NY
Sbjct: 138 LIVGARNYLFRLSLANVSLLQATE------------WASSEDTRRSCQSKGKTEEECQNY 185
Query: 125 IRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAIFA-E 183
+RVL+ + + CGTN+FSP+C S + +L + E+++G ARCP+D ++ A+ + +
Sbjct: 186 VRVLIVAGRKVFM-CGTNAFSPMCTSRQVGNLSRTIEKINGVARCPYDPRHNSTAVISSQ 244
Query: 184 GSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDHVYFFFREV 243
G LY+AT DF D +YRSLG PPLR+A+Y+SKWL EP+FV A + G YFF RE
Sbjct: 245 GELYAATVIDFSGRDPAIYRSLGSGPPLRTAQYNSKWLNEPNFVAAYDIGLFAYFFLREN 304
Query: 244 SVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQAL 303
+VE GR +SRVARVCK D+GG L+ WT+F+K RLNCS PG+ FY++ LQ+
Sbjct: 305 AVEH-DCGRTVYSRVARVCKNDVGGR-FLLEDTWTTFMKARLNCSRPGEVPFYYNELQS- 361
Query: 304 TGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPVSED 363
+L + ++GVFTT NSI SAVCAF L I + F G F+ Q + AW P++ +
Sbjct: 362 --AFHLPEQDLIYGVFTTNVNSIAASAVCAFNLSAISQAFNGPFRYQENPRAAWLPIA-N 418
Query: 364 RVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLTLTSRALL 423
+P+ + G+ G + R L D F L+ AV PVT +P +T S
Sbjct: 419 PIPNFQCGTLPETGPNENL-TERSLQDAQRLF-----LMSEAVQPVTPEPCVTQDS-VRF 471
Query: 424 TQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEIDAYSPARCSGKR 483
+ + VD + + V+++G+ GT+LK L+ RS LEE+ P G+R
Sbjct: 472 SHLVVDLVQAKDTLYHVLYIGTESGTILKALSTASRS--LHGCYLEELHVLPP----GRR 525
Query: 484 TAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGW 539
+ RI+ LFV ++ +PL RCA + + Q +CL ++DPYCGW
Sbjct: 526 EPLRSLRIL-----HSARALFVGLRDGVLRVPLERCAAYRS-QGACLGARDPYCGW 575
>gi|5174673 semaphorin 3A precursor [Homo sapiens]
Length = 771
Score = 279 bits (713), Expect = 1e-74
Identities = 185/540 (34%), Positives = 281/540 (52%), Gaps = 59/540 (10%)
Query: 31 LPLLISDLQGTSPLSWFRGLEDDAVAAELGLDFQRFLTLNRTLLVAARDHVFSFDLQAEE 90
L L ++ ++ + F GL + + LD +R L V A+DH+FSFDL +
Sbjct: 32 LKLSYKEMLESNNVITFNGLANSSSYHTFLLDEER-----SRLYVGAKDHIFSFDLVNIK 86
Query: 91 EGEGLVPNKYLTWRSQDVENCAVRGK-LTDECYNYIRVLVPWDSQTLLACGTNSFSPVCR 149
+ + +V T R + C GK + EC N+I+VL ++ L ACGT +F P+C
Sbjct: 87 DFQKIVWPVSYTRRDE----CKWAGKDILKECANFIKVLKAYNQTHLYACGTGAFHPICT 142
Query: 150 SY--------GITSLQQEGEELSGQARCPFDATQSNVAIFAEGSLYSATAADFQASDAVV 201
I L+ E +G+ + P+D ++ +G LYS TAADF D +
Sbjct: 143 YIEIGHHPEDNIFKLENSHFE-NGRGKSPYDPKLLTASLLIDGELYSGTAADFMGRDFAI 201
Query: 202 YRSLGPQPPLRSAKYDSKWLREPHFVQA-------LEHGDHVYFFFREVSVEDARLGRVQ 254
+R+LG P+R+ ++DS+WL +P F+ A D VYFFFRE +++ G+
Sbjct: 202 FRTLGHHHPIRTEQHDSRWLNDPKFISAHLISESDNPEDDKVYFFFRENAIDGEHSGKAT 261
Query: 255 FSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTF--YFDVLQAL-----TGPV 307
+R+ ++CK D GG R+L WT+FLK RL CSVPG + +FD LQ + P
Sbjct: 262 HARIGQICKNDFGGH-RSLVNKWTTFLKARLICSVPGPNGIDTHFDELQDVFLMNFKDPK 320
Query: 308 NLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPVSEDRVPS 367
N ++GVFTT +N GSAVC + + ++ R F G + + + W P + RVP
Sbjct: 321 N----PVVYGVFTTSSNIFKGSAVCMYSMSDVRRVFLGPYAHRDGPNYQWVPY-QGRVPY 375
Query: 368 PRPGSCAG--VGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLTLTS-RALLT 424
PRPG+C GG F S++DLPDDV+TF ++HP + V P+ ++P++ T T
Sbjct: 376 PRPGTCPSKTFGG---FDSTKDLPDDVITFARSHPAMYNPVFPMNNRPIVIKTDVNYQFT 432
Query: 425 QVAVDGMAGPHSNITVMFLGSNDGTVLKVLT-PGGRSGGPEPILLEEIDAYSPARCSGKR 483
Q+ VD + VMF+G++ GTVLKV++ P E +LLEE+ +
Sbjct: 433 QIVVDRVDAEDGQYDVMFIGTDVGTVLKVVSIPKETWYDLEEVLLEEMTVF--------- 483
Query: 484 TAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHG-ACQRSCLASQDPYCGWHSS 542
+ I +EL T+ +L++ + + LPL RC +G AC CLA +DPYC W S
Sbjct: 484 --REPTAISAMELSTKQQQLYIGSTAGVAQLPLHRCDIYGKACAECCLA-RDPYCAWDGS 540
>gi|147904700 semaphorin 5A [Homo sapiens]
Length = 1074
Score = 277 bits (709), Expect = 3e-74
Identities = 177/474 (37%), Positives = 257/474 (54%), Gaps = 40/474 (8%)
Query: 71 RTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQDVEN--CAVRGKLTDECYNYIRVL 128
+ L+V AR+++F L E L + + W + C +GK +EC NYIRVL
Sbjct: 68 KELVVGARNYLFRLQL------EDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRVL 121
Query: 129 VPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAIF-AEGSLY 187
+ + L CGTN+F+PVC + +++L + +++SG ARCP+ ++ A+ A G LY
Sbjct: 122 LVGGDR-LFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELY 180
Query: 188 SATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDHVYFFFREVSVED 247
+ATA DF D +YRSLG PPLR+A+Y+SKWL EP+FV + + G+ YFFFRE +VE
Sbjct: 181 AATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEH 240
Query: 248 ARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALTGPV 307
G+ FSR ARVCK D+GG L+ WT+F+K RLNCS PG+ FY++ LQ+
Sbjct: 241 -DCGKTVFSRAARVCKNDIGGR-FLLEDTWTTFMKARLNCSRPGEVPFYYNELQS---TF 295
Query: 308 NLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPVSEDRVPS 367
L ++G+FTT NSI SAVC F L I + F G FK Q + AW P P+
Sbjct: 296 FLPELDLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLP-----YPN 350
Query: 368 PRPGSCAGVGGAALF--SSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLTLTSRALLTQ 425
P P G L+ + R+L D FI H + V PVT P + + +
Sbjct: 351 PNPHFQCGTVDQGLYVNLTERNL-QDAQKFILMHEV----VQPVTTVPSF-MEDNSRFSH 404
Query: 426 VAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEIDAYSPARCSGKRTA 485
VAVD + G + + +++L ++ GT+ KV P ++ LLEEI+ + R
Sbjct: 405 VAVDVVQGREALVHIIYLATDYGTIKKVRVPLNQTS--SSCLLEEIELFPERR------- 455
Query: 486 QTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGW 539
I L++ LFV +V +PL RC + + +C+ +QDPYCGW
Sbjct: 456 --REPIRSLQILHSQSVLFVGLREHVVKIPLKRCQFY-RTRSTCIGAQDPYCGW 506
>gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens]
Length = 749
Score = 276 bits (705), Expect = 8e-74
Identities = 195/596 (32%), Positives = 292/596 (48%), Gaps = 54/596 (9%)
Query: 8 MPLLLLLLLLSLPHTQAAFPQDP-LPLLISDLQGTSPLSWFRGLEDDAVAAELGLDFQRF 66
+P L LL + L +A P P L L +LQ L F LE L +D +R
Sbjct: 10 IPGLALLWAVGLG---SAAPSPPRLRLSFQELQAWHGLQTF-SLERTCCYQALLVDEER- 64
Query: 67 LTLNRTLLVAARDHVFSFDLQ-AEEEGEGLVPNKYLTWRSQDVENCAVRGK-LTDECYNY 124
L V A +HV S +L + + L + WR E C GK + EC N+
Sbjct: 65 ----GRLFVGAENHVASLNLDNISKRAKKLAWPAPVEWR----EECNWAGKDIGTECMNF 116
Query: 125 IRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQE-------GEELSGQARCPFDATQSN 177
+++L ++ LLACGT +F P C + +E G G+ + P+D
Sbjct: 117 VKLLHAYNRTHLLACGTGAFHPTCAFVEVGHRAEEPVLRLDPGRIEDGKGKSPYDPRHRA 176
Query: 178 VAIFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQAL------- 230
++ LYS AAD D ++RSLG +P LR+ +DS+WL EP FV+
Sbjct: 177 ASVLVGEELYSGVAADLMGRDFTIFRSLGQRPSLRTEPHDSRWLNEPKFVKVFWIPESEN 236
Query: 231 EHGDHVYFFFREVSVEDA-RLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSV 289
D +YFFFRE +VE A LGR+ SRV ++C+ D+GG R+L WT+FLK RL CSV
Sbjct: 237 PDDDKIYFFFRETAVEAAPALGRLSVSRVGQICRNDVGGQ-RSLVNKWTTFLKARLVCSV 295
Query: 290 PG-DSTFYFDVLQ-ALTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKF 347
PG + +FD LQ H L+ VF+T ++ GSAVC + ++++ R F G F
Sbjct: 296 PGVEGDTHFDQLQDVFLLSSRDHRTPLLYAVFSTSSSIFQGSAVCVYSMNDVRRAFLGPF 355
Query: 348 KEQRSLDGAWTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVP 407
+ W + RVP PRPG C FSS++D PDDV+ F + HPL+ +V
Sbjct: 356 AHKEGPMHQWVSY-QGRVPYPRPGMCPS-KTFGTFSSTKDFPDDVIQFARNHPLMYNSVL 413
Query: 408 PVTHQPL-LTLTSRALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLT-PGGRSGGPEP 465
P +PL L + + TQ+A D +A + V+F+G++ GTVLKV++ P G E
Sbjct: 414 PTGGRPLFLQVGANYTFTQIAADRVAAADGHYDVLFIGTDVGTVLKVISVPKGSRPSAEG 473
Query: 466 ILLEEIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGAC 525
+LLEE+ + + + + +++ ++ H+L+VA + + L RCA HG
Sbjct: 474 LLLEELHVF-----------EDSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAHGRV 522
Query: 526 QRSCLASQDPYCGWHSSRGCVDIRGSGGTDVDQAGNQESMEHGDCQDGATGSQSGP 581
C ++DPYC W C + S + ++ + +GD +G S P
Sbjct: 523 CTECCLARDPYCAW-DGVACTRFQPS----AKRRFRRQDVRNGDPSTLCSGDSSRP 573
>gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens]
Length = 748
Score = 271 bits (693), Expect = 2e-72
Identities = 195/596 (32%), Positives = 292/596 (48%), Gaps = 55/596 (9%)
Query: 8 MPLLLLLLLLSLPHTQAAFPQDP-LPLLISDLQGTSPLSWFRGLEDDAVAAELGLDFQRF 66
+P L LL + L +A P P L L +LQ L F LE L +D +R
Sbjct: 10 IPGLALLWAVGLG---SAAPSPPRLRLSFQELQAWHGLQTF-SLERTCCYQALLVDEER- 64
Query: 67 LTLNRTLLVAARDHVFSFDLQ-AEEEGEGLVPNKYLTWRSQDVENCAVRGK-LTDECYNY 124
L V A +HV S +L + + L + WR E C GK + EC N+
Sbjct: 65 ----GRLFVGAENHVASLNLDNISKRAKKLAWPAPVEWR----EECNWAGKDIGTECMNF 116
Query: 125 IRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQE-------GEELSGQARCPFDATQSN 177
+++L ++ LLACGT +F P C + +E G G+ + P+D
Sbjct: 117 VKLLHAYNRTHLLACGTGAFHPTCAFVEVGHRAEEPVLRLDPGRIEDGKGKSPYDPRHRA 176
Query: 178 VAIFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQAL------- 230
++ LYS AAD D ++RSLG +P LR+ +DS+WL EP FV+
Sbjct: 177 ASVLVGEELYSGVAADLMGRDFTIFRSLGQRPSLRTEPHDSRWLNEPKFVKVFWIPESEN 236
Query: 231 EHGDHVYFFFREVSVEDA-RLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSV 289
D +YFFFRE +VE A LGR+ SRV ++C+ D+GG R+L WT+FLK RL CSV
Sbjct: 237 PDDDKIYFFFRETAVEAAPALGRLSVSRVGQICRNDVGGQ-RSLVNKWTTFLKARLVCSV 295
Query: 290 PG-DSTFYFDVLQ-ALTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKF 347
PG + +FD LQ H L+ VF+T ++ GSAVC + ++++ R F G F
Sbjct: 296 PGVEGDTHFDQLQDVFLLSSRDHRTPLLYAVFST-SSIFQGSAVCVYSMNDVRRAFLGPF 354
Query: 348 KEQRSLDGAWTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVP 407
+ W + RVP PRPG C FSS++D PDDV+ F + HPL+ +V
Sbjct: 355 AHKEGPMHQWVSY-QGRVPYPRPGMCPS-KTFGTFSSTKDFPDDVIQFARNHPLMYNSVL 412
Query: 408 PVTHQPL-LTLTSRALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLT-PGGRSGGPEP 465
P +PL L + + TQ+A D +A + V+F+G++ GTVLKV++ P G E
Sbjct: 413 PTGGRPLFLQVGANYTFTQIAADRVAAADGHYDVLFIGTDVGTVLKVISVPKGSRPSAEG 472
Query: 466 ILLEEIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGAC 525
+LLEE+ + + + + +++ ++ H+L+VA + + L RCA HG
Sbjct: 473 LLLEELHVF-----------EDSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAHGRV 521
Query: 526 QRSCLASQDPYCGWHSSRGCVDIRGSGGTDVDQAGNQESMEHGDCQDGATGSQSGP 581
C ++DPYC W C + S + ++ + +GD +G S P
Sbjct: 522 CTECCLARDPYCAW-DGVACTRFQPS----AKRRFRRQDVRNGDPSTLCSGDSSRP 572
>gi|41406086 semaphorin 3D [Homo sapiens]
Length = 777
Score = 266 bits (681), Expect = 5e-71
Identities = 188/564 (33%), Positives = 268/564 (47%), Gaps = 56/564 (9%)
Query: 6 HFMPLLLLL--LLLSLPHTQAAFPQDP-LPLLISDLQGTSPLSWFRGLEDDAVAAELGLD 62
H P L++L +L LP T P L L DL ++ F G + GLD
Sbjct: 17 HLFPALMMLSMTMLFLPVTGTLKQNIPRLKLTYKDLLLSNSCIPFLGSSE-------GLD 69
Query: 63 FQRFLTLNRT--LLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQDVENCAVRGK-LTD 119
FQ L LL+ A+DH+F L + + Y + VE C + GK
Sbjct: 70 FQTLLLDEERGRLLLGAKDHIFLLSLVDLNKNFKKI---YWPAAKERVELCKLAGKDANT 126
Query: 120 ECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEEL----------SGQARC 169
EC N+IRVL P++ + CGT +F P+C G L E++ SG+ +C
Sbjct: 127 ECANFIRVLQPYNKTHIYVCGTGAFHPIC---GYIDLGVYKEDIIFKLDTHNLESGRLKC 183
Query: 170 PFDATQSNVAIFAEGSLYSATAADFQASDAVVYRSLGPQPP---LRSAKYDSKWLREPHF 226
PFD Q ++ + LYS TA+DF D RSLGP +R+ + WL F
Sbjct: 184 PFDPQQPFASVMTDEYLYSGTASDFLGKDTAFTRSLGPTHDHHYIRTDISEHYWLNGAKF 243
Query: 227 VQAL-------EHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTS 279
+ D +YFFFRE S E + + SRV RVCK D+GG R+L WT+
Sbjct: 244 IGTFFIPDTYNPDDDKIYFFFRESSQEGSTSDKTILSRVGRVCKNDVGGQ-RSLINKWTT 302
Query: 280 FLKLRLNCSVPGD--STFYFDVLQAL-TGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYL 336
FLK RL CS+PG + YFD LQ + P ++GVFTT ++ GSAVC + +
Sbjct: 303 FLKARLICSIPGSDGADTYFDELQDIYLLPTRDERNPVVYGVFTTTSSIFKGSAVCVYSM 362
Query: 337 DEIERGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFI 396
+I F G + + S D W + R+P PRPG+C L S+RD PDDV++FI
Sbjct: 363 ADIRAVFNGPYAHKESADHRWVQY-DGRIPYPRPGTCPSKTYDPLIKSTRDFPDDVISFI 421
Query: 397 KAHPLLDPAVPPVTHQPLL-TLTSRALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLT 455
K H ++ +V PV P + LTQ+ VD + VMFLG++ GTVLKV++
Sbjct: 422 KRHSVMYKSVYPVAGGPTFKRINVDYRLTQIVVDHVIAEDGQYDVMFLGTDIGTVLKVVS 481
Query: 456 PGGRSGGPEPILLEEIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLP 515
E ++LEE+ + + I+ +EL + +L++ +V L
Sbjct: 482 ISKEKWNMEEVVLEELQIFKHSSI-----------ILNMELSLKQQQLYIGSRDGLVQLS 530
Query: 516 LSRCARHGACQRSCLASQDPYCGW 539
L RC +G C ++DPYC W
Sbjct: 531 LHRCDTYGKACADCCLARDPYCAW 554
>gi|157388902 semaphorin 4C [Homo sapiens]
Length = 833
Score = 261 bits (668), Expect = 2e-69
Identities = 182/517 (35%), Positives = 269/517 (52%), Gaps = 58/517 (11%)
Query: 64 QRFLTLNRT-----LLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRS--QDVENCAVRGK 116
Q FLTL T L V AR+ +F+F ++A E +G + +W + + C +GK
Sbjct: 51 QDFLTLTLTEPTGLLYVGAREALFAFSMEALEL-QGAI-----SWEAPVEKKTECIQKGK 104
Query: 117 LTD-ECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYG-ITSLQQEGEELSGQARCPFDAT 174
EC+N+IR L P+++ L CGT +F P C +T + GE G+ +CP+D
Sbjct: 105 NNQTECFNFIRFLQPYNASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPA 164
Query: 175 QSNVAIFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQA----- 229
+ + + +G LYSAT +F ++ ++ R++GP +++ +Y + WL EPHFV +
Sbjct: 165 KGHAGLLVDGELYSATLNNFLGTEPIILRNMGPHHSMKT-EYLAFWLNEPHFVGSAYVPE 223
Query: 230 -----LEHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLR 284
D VYFFFRE +VE +RVARVCK DMGG+ R L R WT+FLK R
Sbjct: 224 SVGSFTGDDDKVYFFFRERAVESDCYAEQVVARVARVCKGDMGGA-RTLQRKWTTFLKAR 282
Query: 285 LNCSVPGDSTFYFDVLQAL-TGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGF 343
L CS P + YF+ LQA+ T + FGVF Q + SA+C + L+EI+R F
Sbjct: 283 LACSAP-NWQLYFNQLQAMHTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVF 341
Query: 344 EGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGGAAL-FSSSRDLPDDVLTFIKAHPLL 402
EG +KE W + D VPSPRPGSC ++SS +LPD++L F+K HPL+
Sbjct: 342 EGPYKEYHEEAQKWDRYT-DPVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLM 400
Query: 403 DPAVPPVTHQPLLTL--TSRALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRS 460
+ V P +PLL T+ L V G+ G + TV+F+G+ DG +LK + S
Sbjct: 401 EEQVGPRWSRPLLVKKGTNFTHLVADRVTGLDG--ATYTVLFIGTGDGWLLKAV-----S 453
Query: 461 GGPEPILLEEIDAY--SPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSR 518
GP L+EE+ + P R L L LF +V LP++
Sbjct: 454 LGPWVHLIEELQLFDQEPMR--------------SLVLSQSKKLLFAGSRSQLVQLPVAD 499
Query: 519 CARHGACQRSCLASQDPYCGWH-SSRGCVDIRGSGGT 554
C ++ +C C+ ++DPYC W ++ CV + G G+
Sbjct: 500 CMKYRSC-ADCVLARDPYCAWSVNTSRCVAVGGHSGS 535
>gi|6912650 semaphorin 3E [Homo sapiens]
Length = 775
Score = 258 bits (660), Expect = 1e-68
Identities = 171/578 (29%), Positives = 271/578 (46%), Gaps = 66/578 (11%)
Query: 46 WFRGLEDDAVAAELGLDFQRFLTLNRT-----------------------LLVAARDHVF 82
W G D L L + L LNRT L V RD V+
Sbjct: 20 WTGGHTADTTHPRLRLSHKELLNLNRTSIFHSPFGFLDLHTMLLDEYQERLFVGGRDLVY 79
Query: 83 SFDLQAEEEGEGLVPNKYLTWRSQ--DVENCAVRGKLTDECYNYIRVLVPWDSQTLLACG 140
S L+ +G K + W S +E C ++GK EC NY+RVL ++ LL CG
Sbjct: 80 SLSLERISDGY-----KEIHWPSTALKMEECIMKGKDAGECANYVRVLHHYNRTHLLTCG 134
Query: 141 TNSFSPVCRSYGIT--------SLQQEGEELSGQARCPFDATQSNVAIFAEGSLYSATAA 192
T +F PVC + L+ E G+ RCPFD + S ++ L++ +
Sbjct: 135 TGAFDPVCAFIRVGYHLEDPLFHLESPRSE-RGRGRCPFDPSSSFISTLIGSELFAGLYS 193
Query: 193 DFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDH-------VYFFFREVSV 245
D+ + DA ++RS+G +R+ D + L+EP FV + D+ VYFFF E ++
Sbjct: 194 DYWSRDAAIFRSMGRLAHIRTEHDDERLLKEPKFVGSYMIPDNEDRDDNKVYFFFTEKAL 253
Query: 246 EDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTF--YFDVLQ-A 302
E ++RV R+C D+GG R L W++FLK RL CSVPG + YFD L+
Sbjct: 254 EAENNAHAIYTRVGRLCVNDVGGQ-RILVNKWSTFLKARLVCSVPGMNGIDTYFDELEDV 312
Query: 303 LTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPVSE 362
P H +FG+F T +N G A+C +++ I F G + + + W+ V E
Sbjct: 313 FLLPTRDHKNPVIFGLFNTTSNIFRGHAICVYHMSSIRAAFNGPYAHKEGPEYHWS-VYE 371
Query: 363 DRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLTLT-SRA 421
+VP PRPGSCA + +++D PDD + F ++HPL+ A+ P +P+L T +
Sbjct: 372 GKVPYPRPGSCASKVNGGRYGTTKDYPDDAIRFARSHPLMYQAIKPAHKKPILVKTDGKY 431
Query: 422 LLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRS-GGPEPILLEEIDAYSPARCS 480
L Q+AVD + V+F+G+++G VLKV+T + E ++LEE+ +
Sbjct: 432 NLKQIAVDRVEAEDGQYDVLFIGTDNGIVLKVITIYNQEMESMEEVILEELQIF------ 485
Query: 481 GKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGWH 540
+ II +E+ ++ +L++ + + + C +G+ C ++DPYC W
Sbjct: 486 -----KDPVPIISMEISSKRQQLYIGSASAVAQVRFHHCDMYGSACADCCLARDPYCAW- 539
Query: 541 SSRGCVDIRGSGGTDVDQAGNQESMEHGDCQDGATGSQ 578
C + GT + ++ + HG+ G Q
Sbjct: 540 DGISCSRYYPT-GTHAKRRFRRQDVRHGNAAQQCFGQQ 576
>gi|39777610 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 246 bits (627), Expect = 9e-65
Identities = 194/570 (34%), Positives = 277/570 (48%), Gaps = 71/570 (12%)
Query: 2 PRAPHFMPLLLLLLLLSLPHTQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAELGL 61
PR P + LLLLLLL P T A P+ LPL G+ + R E + ++ L
Sbjct: 21 PRPPLLLLLLLLLLLQPPPPTWALSPRISLPL------GSEERPFLR-FEAEHISNYTAL 73
Query: 62 DFQRFLTLNRTLLVAARDHVF--SFDLQAEEEGEGLVPNKYLTWRS--QDVENCAVRGKL 117
R RTL V AR+ +F S +L GE + L W + + + C+ +GK
Sbjct: 74 LLSRD---GRTLYVGAREALFALSSNLSFLPGGE----YQELLWGADAEKKQQCSFKGKD 126
Query: 118 TD-ECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSL----QQEGEEL--SGQARCP 170
+C NYI++L+P L CGT +FSP+C + + ++G L G+ RCP
Sbjct: 127 PQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCP 186
Query: 171 FDATQSNVAIFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDS--KWLREPHFVQ 228
FD + A+ +G LY+ T + FQ +D + RS LR K +S WL++P FV
Sbjct: 187 FDPNFKSTALVVDGELYTGTVSSFQGNDPAISRS----QSLRPTKTESSLNWLQDPAFVA 242
Query: 229 AL----------EHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWT 278
+ D +YFFF E E SR+AR+CK D GG R L + WT
Sbjct: 243 SAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGE-RVLQQRWT 301
Query: 279 SFLKLRLNCSVPGDSTFYFDVLQAL--TGPVNLHGRSALF-GVFTTQ--TNSIPGSAVCA 333
SFLK +L CS P D F F+VLQ + P R LF GVFT+Q + GSAVC
Sbjct: 302 SFLKAQLLCSRPDDG-FPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCV 360
Query: 334 FYLDEIERGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSC-AGVGGAALFSSSRDLPDDV 392
F + +++R F G +KE W V+ VP+PRPG+C +SS LPD V
Sbjct: 361 FTMKDVQRVFSGLYKEVNRETQQWYTVTHP-VPTPRPGACITNSARERKINSSLQLPDRV 419
Query: 393 LTFIKAHPLLDPAVPPVTHQPLLTLTSRALLTQVAVDGMAGPHSNITVMFLGSNDGTVLK 452
L F+K H L+D V +L L +A +VAV + G H V+FLG+ DG + K
Sbjct: 420 LNFLKDHFLMDGQV----RSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHK 475
Query: 453 VLTPGGRSGGPEPILLEEIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIV 512
+ S GP ++EE+ +S + + + L LDT L+ A +V
Sbjct: 476 AV-----SVGPRVHIIEELQIFS-----------SGQPVQNLLLDTHRGLLYAASHSGVV 519
Query: 513 YLPLSRCARHGACQRSCLASQDPYCGWHSS 542
+P++ C+ + +C CL ++DPYC W S
Sbjct: 520 QVPMANCSLYRSC-GDCLLARDPYCAWSGS 548
>gi|39777608 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 246 bits (627), Expect = 9e-65
Identities = 194/570 (34%), Positives = 277/570 (48%), Gaps = 71/570 (12%)
Query: 2 PRAPHFMPLLLLLLLLSLPHTQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAELGL 61
PR P + LLLLLLL P T A P+ LPL G+ + R E + ++ L
Sbjct: 21 PRPPLLLLLLLLLLLQPPPPTWALSPRISLPL------GSEERPFLR-FEAEHISNYTAL 73
Query: 62 DFQRFLTLNRTLLVAARDHVF--SFDLQAEEEGEGLVPNKYLTWRS--QDVENCAVRGKL 117
R RTL V AR+ +F S +L GE + L W + + + C+ +GK
Sbjct: 74 LLSRD---GRTLYVGAREALFALSSNLSFLPGGE----YQELLWGADAEKKQQCSFKGKD 126
Query: 118 TD-ECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSL----QQEGEEL--SGQARCP 170
+C NYI++L+P L CGT +FSP+C + + ++G L G+ RCP
Sbjct: 127 PQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCP 186
Query: 171 FDATQSNVAIFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDS--KWLREPHFVQ 228
FD + A+ +G LY+ T + FQ +D + RS LR K +S WL++P FV
Sbjct: 187 FDPNFKSTALVVDGELYTGTVSSFQGNDPAISRS----QSLRPTKTESSLNWLQDPAFVA 242
Query: 229 AL----------EHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWT 278
+ D +YFFF E E SR+AR+CK D GG R L + WT
Sbjct: 243 SAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGE-RVLQQRWT 301
Query: 279 SFLKLRLNCSVPGDSTFYFDVLQAL--TGPVNLHGRSALF-GVFTTQ--TNSIPGSAVCA 333
SFLK +L CS P D F F+VLQ + P R LF GVFT+Q + GSAVC
Sbjct: 302 SFLKAQLLCSRPDDG-FPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCV 360
Query: 334 FYLDEIERGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSC-AGVGGAALFSSSRDLPDDV 392
F + +++R F G +KE W V+ VP+PRPG+C +SS LPD V
Sbjct: 361 FTMKDVQRVFSGLYKEVNRETQQWYTVTHP-VPTPRPGACITNSARERKINSSLQLPDRV 419
Query: 393 LTFIKAHPLLDPAVPPVTHQPLLTLTSRALLTQVAVDGMAGPHSNITVMFLGSNDGTVLK 452
L F+K H L+D V +L L +A +VAV + G H V+FLG+ DG + K
Sbjct: 420 LNFLKDHFLMDGQV----RSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHK 475
Query: 453 VLTPGGRSGGPEPILLEEIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIV 512
+ S GP ++EE+ +S + + + L LDT L+ A +V
Sbjct: 476 AV-----SVGPRVHIIEELQIFS-----------SGQPVQNLLLDTHRGLLYAASHSGVV 519
Query: 513 YLPLSRCARHGACQRSCLASQDPYCGWHSS 542
+P++ C+ + +C CL ++DPYC W S
Sbjct: 520 QVPMANCSLYRSC-GDCLLARDPYCAWSGS 548
>gi|188497703 semaphorin 3F [Homo sapiens]
Length = 785
Score = 241 bits (615), Expect = 2e-63
Identities = 159/520 (30%), Positives = 253/520 (48%), Gaps = 73/520 (14%)
Query: 73 LLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRS--QDVENCAVRGK-LTDECYNYIRVLV 129
+ V ++D+V S DL + E L+ + W + Q +E C + GK + EC N++R++
Sbjct: 69 MYVGSKDYVLSLDLH-DINREPLI----IHWAASPQRIEECVLSGKDVNGECGNFVRLIQ 123
Query: 130 PWDSQTLLACGTNSFSPVC---------------------------------------RS 150
PW+ L CGT +++P+C R
Sbjct: 124 PWNRTHLYVCGTGAYNPMCTYVNRGRRAQATPWTQTQAVRGRGSRATDGALRPMPTAPRQ 183
Query: 151 YGITSLQQEGEELSGQARCPFDATQSNVAIFAEGSLYSATAADFQASDAVVYRSLGPQPP 210
I L+ E E SG+ +CP+D + LY+ DF +DA ++R+LG Q
Sbjct: 184 DYIFYLEPERLE-SGKGKCPYDPKLDTASALINEELYAGVYIDFMGTDAAIFRTLGKQTA 242
Query: 211 LRSAKYDSKWLREPHFV-------QALEHGDHVYFFFREVSVEDARLGRVQFSRVARVCK 263
+R+ +Y+S+WL +P F+ A + D +YFFFRE S E + V ++R+ R+C
Sbjct: 243 MRTDQYNSRWLNDPSFIHAELIPDSAERNDDKLYFFFRERSAEAPQSPAV-YARIGRICL 301
Query: 264 RDMGGSPRALDRHWTSFLKLRLNCSVPGDSTF--YFDVLQALTGPVNLHGRS-ALFGVFT 320
D GG L W++FLK RL CSVPG+ +FD LQ + R+ ++ VFT
Sbjct: 302 NDDGGH-CCLVNKWSTFLKARLVCSVPGEDGIETHFDELQDVFVQQTQDVRNPVIYAVFT 360
Query: 321 TQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGGAA 380
+ + GSAVC + + +I F G F + + W P S ++P PRPG+C G
Sbjct: 361 SSGSVFRGSAVCVYSMADIRMVFNGPFAHKEGPNYQWMPFS-GKMPYPRPGTCPGGTFTP 419
Query: 381 LFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLTLTSRAL-LTQVAVDGMAGPHSNIT 439
S++D PD+V+ F+++HPL+ AV P+ +PL+ T LT +AVD +
Sbjct: 420 SMKSTKDYPDEVINFMRSHPLMYQAVYPLQRRPLVVRTGAPYRLTTIAVDQVDAADGRYE 479
Query: 440 VMFLGSNDGTVLKVLTPGGRSGGPEPILLEEIDAYSPARCSGKRTAQTARRIIGLELDTE 499
V+FLG++ GTV KV+ E ++LEE++ + T + R+
Sbjct: 480 VLFLGTDRGTVQKVIVLPKDDQELEELMLEEVEVFKDPAPVKTMTISSKRQ--------- 530
Query: 500 GHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGW 539
+L+VA + + +L L RC +GA C ++DPYC W
Sbjct: 531 --QLYVASAVGVTHLSLHRCQAYGAACADCCLARDPYCAW 568
>gi|214010220 semaphorin 4D isoform 2 [Homo sapiens]
Length = 738
Score = 234 bits (597), Expect = 3e-61
Identities = 174/496 (35%), Positives = 248/496 (50%), Gaps = 62/496 (12%)
Query: 72 TLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWR-SQDVE-NCAVRGKLTD-ECYNYIRVL 128
TL + AR+ VF+ + E + V W+ S+D + CA +GK EC NYIRVL
Sbjct: 61 TLYIGAREAVFAVNALNISEKQHEV-----YWKVSEDKKAKCAEKGKSKQTECLNYIRVL 115
Query: 129 VPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAIFAEGSLYS 188
P + +L CGTN+F P C +TS + G+ G+ RCPFD S ++ +G LYS
Sbjct: 116 QPLSATSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYS 175
Query: 189 ATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALE----------HGDHVYF 238
T+ +F S+ ++ R+ PLR+ +Y WL EP FV A D VYF
Sbjct: 176 GTSYNFLGSEPIISRN-SSHSPLRT-EYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYF 233
Query: 239 FFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFD 298
FF EVSVE + RV R+ARVCK D GG R L + WTSFLK RL CS P DS F+
Sbjct: 234 FFTEVSVEYEFVFRVLIPRIARVCKGDQGGL-RTLQKKWTSFLKARLICSRP-DSGLVFN 291
Query: 299 VLQ--------ALTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFE-GKFKE 349
VL+ L PV + +FT Q N++ SAVCA+ L E F GK+ +
Sbjct: 292 VLRDVFVLRSPGLKVPV-------FYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQ 344
Query: 350 QRSLDGAWTPVSEDR--VPSPRPGSCA-GVGGAALFSSSRDLPDDVLTFIKAHPLLDPAV 406
+++ + T VP PRPG+C AA ++SS +LPD L F+K HPL+D +V
Sbjct: 345 STTVEQSHTKWVRYNGPVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSV 404
Query: 407 PPVTHQPLLTLTSRALLTQVAVDGMAGPHSNI-TVMFLGSNDGTVLKVLT-PGGRSGGPE 464
P+ ++P L + TQ+ VD + VMF+ ++ G + K ++ E
Sbjct: 405 TPIDNRPRL-IKKDVNYTQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEE 463
Query: 465 PILLEEIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGC-IVYLPLSRCARHG 523
L ++ + S K+ G+R A S +V PL+ C +HG
Sbjct: 464 TQLFQDFEPVQTLLLSSKK----------------GNRFVYAGSNSGVVQAPLAFCGKHG 507
Query: 524 ACQRSCLASQDPYCGW 539
C+ C+ ++DPYC W
Sbjct: 508 TCE-DCVLARDPYCAW 522
>gi|214010218 semaphorin 4D isoform 1 [Homo sapiens]
Length = 862
Score = 234 bits (597), Expect = 3e-61
Identities = 174/496 (35%), Positives = 248/496 (50%), Gaps = 62/496 (12%)
Query: 72 TLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWR-SQDVE-NCAVRGKLTD-ECYNYIRVL 128
TL + AR+ VF+ + E + V W+ S+D + CA +GK EC NYIRVL
Sbjct: 61 TLYIGAREAVFAVNALNISEKQHEV-----YWKVSEDKKAKCAEKGKSKQTECLNYIRVL 115
Query: 129 VPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAIFAEGSLYS 188
P + +L CGTN+F P C +TS + G+ G+ RCPFD S ++ +G LYS
Sbjct: 116 QPLSATSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYS 175
Query: 189 ATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALE----------HGDHVYF 238
T+ +F S+ ++ R+ PLR+ +Y WL EP FV A D VYF
Sbjct: 176 GTSYNFLGSEPIISRN-SSHSPLRT-EYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYF 233
Query: 239 FFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFD 298
FF EVSVE + RV R+ARVCK D GG R L + WTSFLK RL CS P DS F+
Sbjct: 234 FFTEVSVEYEFVFRVLIPRIARVCKGDQGGL-RTLQKKWTSFLKARLICSRP-DSGLVFN 291
Query: 299 VLQ--------ALTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFE-GKFKE 349
VL+ L PV + +FT Q N++ SAVCA+ L E F GK+ +
Sbjct: 292 VLRDVFVLRSPGLKVPV-------FYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQ 344
Query: 350 QRSLDGAWTPVSEDR--VPSPRPGSCA-GVGGAALFSSSRDLPDDVLTFIKAHPLLDPAV 406
+++ + T VP PRPG+C AA ++SS +LPD L F+K HPL+D +V
Sbjct: 345 STTVEQSHTKWVRYNGPVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSV 404
Query: 407 PPVTHQPLLTLTSRALLTQVAVDGMAGPHSNI-TVMFLGSNDGTVLKVLT-PGGRSGGPE 464
P+ ++P L + TQ+ VD + VMF+ ++ G + K ++ E
Sbjct: 405 TPIDNRPRL-IKKDVNYTQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEE 463
Query: 465 PILLEEIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGC-IVYLPLSRCARHG 523
L ++ + S K+ G+R A S +V PL+ C +HG
Sbjct: 464 TQLFQDFEPVQTLLLSSKK----------------GNRFVYAGSNSGVVQAPLAFCGKHG 507
Query: 524 ACQRSCLASQDPYCGW 539
C+ C+ ++DPYC W
Sbjct: 508 TCE-DCVLARDPYCAW 522
>gi|9910362 semaphorin sem2 [Homo sapiens]
Length = 782
Score = 232 bits (592), Expect = 1e-60
Identities = 165/488 (33%), Positives = 241/488 (49%), Gaps = 49/488 (10%)
Query: 109 ENCAVRGK--LTDECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEEL--- 163
E C +G+ LT EC N++RVL P + LLACGT +F P C + ++ GE +
Sbjct: 103 EECVRKGRDPLT-ECANFVRVLQPHNRTHLLACGTGAFQPTC---ALITVGHRGEHVLHL 158
Query: 164 ------SGQARCPFDATQSNVAIFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYD 217
SG+ RCP + ++ + F +G LY+ ADF +A+++RS GP+P LRS D
Sbjct: 159 EPGSVESGRGRCPHEPSRPFASTFIDGELYTGLTADFLGREAMIFRSGGPRPALRSDS-D 217
Query: 218 SKWLREPHFVQAL-------EHGDHVYFFFRE-VSVEDARLGRVQFSRVARVCKRDMGGS 269
L +P FV A + D VYFFF E V D V SRV RVC D GG
Sbjct: 218 QSLLHDPRFVMAARIPENSDQDNDKVYFFFSETVPSPDGGSNHVTVSRVGRVCVNDAGGQ 277
Query: 270 PRALDRHWTSFLKLRLNCSV--PGDSTFYFDVLQALTGPVNLHGRS-ALFGVFTTQTNSI 326
R L W++FLK RL CSV PG + +FD L+ + G+S ++ +F+T +
Sbjct: 278 -RVLVNKWSTFLKARLVCSVPGPGGAETHFDQLEDVFLLWPKAGKSLEVYALFSTVSAVF 336
Query: 327 PGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGGA---ALFS 383
G AVC +++ +I F G F + W P +VP PRPG C A F
Sbjct: 337 QGFAVCVYHMADIWEVFNGPFAHRDGPQHQWGPYG-GKVPFPRPGVCPSKMTAQPGRPFG 395
Query: 384 SSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLTLTSRA-LLTQVAVDGMAGPHSNITVMF 442
S++D PD+VL F +AHPL+ V P +P+L T A L Q+ VD + V+F
Sbjct: 396 STKDYPDEVLQFARAHPLMFWPVRPRHGRPVLVKTHLAQQLHQIVVDRVEAEDGTYDVIF 455
Query: 443 LGSNDGTVLKVLT-PGGRSGGPEPILLEEIDAYSPARCSGKRTAQTARRIIGLELDTEGH 501
LG++ G+VLKV+ G S PE ++LEE+ + + I +E+ +
Sbjct: 456 LGTDSGSVLKVIALQAGGSAEPEEVVLEELQVF-----------KVPTPITEMEISVKRQ 504
Query: 502 RLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGWHSSRGCVDIRGSGGTDVDQAGN 561
L+V + L L +C +G C ++DPYC W + C R S G +
Sbjct: 505 MLYVGSRLGVAQLRLHQCETYGTACAECCLARDPYCAWDGA-SCTHYRPSLG---KRRFR 560
Query: 562 QESMEHGD 569
++ + HG+
Sbjct: 561 RQDIRHGN 568
>gi|5454048 semaphorin 3C [Homo sapiens]
Length = 751
Score = 226 bits (575), Expect = 1e-58
Identities = 148/485 (30%), Positives = 253/485 (52%), Gaps = 34/485 (7%)
Query: 73 LLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQDVENCAVRGK-LTDECYNYIRVLVPW 131
+ V ++DH+ S ++ + E L + + + VE C + GK T C N++RV+ +
Sbjct: 66 IYVGSKDHILSLNINNISQ-EAL--SVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTF 122
Query: 132 DSQTLLACGTNSFSPVCR--SYGITSLQQ----EGEELSGQARCPFDATQSNVAIFAEGS 185
+ L CG+ +FSPVC + G S Q + + SG+ RC F+ + V++
Sbjct: 123 NRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEE 182
Query: 186 LYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGD-------HVYF 238
L+S DF +DA ++RSL + +R+ +++SKWL EP FV A D VYF
Sbjct: 183 LFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYF 242
Query: 239 FFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDS--TFY 296
FF+E ++ R + S +AR+C D GG R+L WT+FLK RL CSV + +
Sbjct: 243 FFKEKLTDNNRSTKQIHSMIARICPNDTGGL-RSLVNKWTTFLKARLVCSVTDEDGPETH 301
Query: 297 FDVLQALTGPVNLHGRSAL-FGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDG 355
FD L+ + + R+ L +G+FTT ++ GSAVC ++L +I+ F G F + +
Sbjct: 302 FDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNH 361
Query: 356 AWTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLL 415
+ R+P PRPG+C G ++++ PDDV+TFI+ HPL+ ++ P+ +PL+
Sbjct: 362 QLISY-QGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLI 420
Query: 416 T-LTSRALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEIDAY 474
+ + T++AVD + V+FLG++ GTV KV+ + ++LEE++ +
Sbjct: 421 VRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVF 480
Query: 475 SPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQD 534
+ I +++ ++ +L+V+ + + + L RC +G C ++D
Sbjct: 481 -----------KNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARD 529
Query: 535 PYCGW 539
PYC W
Sbjct: 530 PYCAW 534
>gi|21361914 semaphorin B [Homo sapiens]
Length = 761
Score = 218 bits (554), Expect = 3e-56
Identities = 179/554 (32%), Positives = 271/554 (48%), Gaps = 67/554 (12%)
Query: 11 LLLLLLLSLPHTQAAFP-QDPLPLLISDLQGTSPLSWFRGLEDDAVAAELGLDFQRFLTL 69
L LL L LP T A Q P+P + ++ G E A++ Q F TL
Sbjct: 18 LFQLLQLLLPTTTAGGGGQGPMPRV----------RYYAGDERRALSFFHQKGLQDFDTL 67
Query: 70 -----NRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQDVEN--CAVRGKLTD-EC 121
TL V AR+ + + D+Q + G + N + W + D + CA + K + +C
Sbjct: 68 LLSGDGNTLYVGAREAILALDIQ--DPGVPRLKNM-IPWPASDRKKSECAFKKKSNETQC 124
Query: 122 YNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQ----QEGEELSGQARCPFDATQSN 177
+N+IRVLV ++ L CGT +FSP C + E + + G+ + PFD +
Sbjct: 125 FNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDPAHKH 184
Query: 178 VAIFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLR-EPHFVQALEHGDHV 236
A+ +G LYS T +F S+ ++ R+LG QP L++ + +WL + FV A+ V
Sbjct: 185 TAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHDASFVAAIPSTQVV 243
Query: 237 YFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFY 296
YFFF E + E R+ SRVARVCK D+GG + L + WT+FLK +L C+ PG F
Sbjct: 244 YFFFEETASEFDFFERLHTSRVARVCKNDVGGE-KLLQKKWTTFLKAQLLCTQPGQLPFN 302
Query: 297 FDVLQALTGPVNLHGRSALFGVFTT--QTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLD 354
+ A+ P + ++ VFT+ Q SAVCAF L +IER F+GK+KE
Sbjct: 303 V-IRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKET 361
Query: 355 GAWTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAV--PPVTHQ 412
WT +PRPGSC+ VG ++ D LTF+K H L+D V P+ +
Sbjct: 362 SRWTTYRGPET-NPRPGSCS-VGPSS---------DKALTFMKDHFLMDEQVVGTPLLVK 410
Query: 413 PLLTLTSRALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEID 472
+ T A+ T +DG HS++ VM+LG+ G++ K + G S L+EEI
Sbjct: 411 SGVEYTRLAVETAQGLDG----HSHL-VMYLGTTTGSLHKAVVSGDSSAH----LVEEIQ 461
Query: 473 AYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLAS 532
+ + L+L +FV FSG + +P + C+ + +C C+ +
Sbjct: 462 LF-----------PDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESCV-DCVLA 509
Query: 533 QDPYCGWH-SSRGC 545
+DP+C W SR C
Sbjct: 510 RDPHCAWDPESRTC 523
>gi|19923279 semaphorin W [Homo sapiens]
Length = 770
Score = 214 bits (545), Expect = 3e-55
Identities = 157/496 (31%), Positives = 229/496 (46%), Gaps = 63/496 (12%)
Query: 70 NRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQDV--ENCAVRGKLTDECYNYIRV 127
+ TL V ARD +F+ L E + + W + +NC +GK DEC+N++++
Sbjct: 74 SHTLYVGARDTIFALSLPFSGERP-----RRIDWMVPEAHRQNCRKKGKKEDECHNFVQI 128
Query: 128 LVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAIFAEGSLY 187
L ++ LL CGT +F P C ++ QQ SG+ +CPF+ Q + A+ A G LY
Sbjct: 129 LAIANASHLLTCGTFAFDPKCGVIDVSRFQQVERLESGRGKCPFEPAQRSAAVMAGGVLY 188
Query: 188 SATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQAL----------EHGDHVY 237
+AT ++ ++ ++ R++G WL P FV A+ + D +Y
Sbjct: 189 AATVKNYLGTEPIITRAVGRAEDWIRTDTLPSWLNAPAFVAAVALSPAEWGDEDGDDEIY 248
Query: 238 FFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGD---ST 294
FFF E S R++ RVARVC D+GG + L + WT+FLK L C P S+
Sbjct: 249 FFFTETSRAFDSYERIKVPRVARVCAGDLGGR-KTLQQRWTTFLKADLLCPGPEHGRASS 307
Query: 295 FYFDVLQALTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLD 354
DV A+ P G +G+F++Q SAVCAF +I G F+E +
Sbjct: 308 VLQDV--AVLRPELGAGTPIFYGIFSSQWEGATISAVCAFRPQDIRTVLNGPFRELKHDC 365
Query: 355 GAWTPVSEDRVPSPRPGSCAGVGGAAL--FSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQ 412
PV ++ VP PRPG C L F SS LPD VLTFI+ HPL+D V P
Sbjct: 366 NRGLPVVDNDVPQPRPGECI-TNNMKLRHFGSSLSLPDRVLTFIRDHPLMDRPVFPADGH 424
Query: 413 PLLTLTSRALLTQVA--VDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSG-------GP 463
PLL T A L VA V ++G V++LG+ DG + + + G + P
Sbjct: 425 PLLVTTDTAYLRVVAHRVTSLSG--KEYDVLYLGTEDGHLHRAVRIGAQLSVLEDLALFP 482
Query: 464 EPILLEEIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHG 523
EP +E + Y G RT T +++T + C R
Sbjct: 483 EPQPVENMKLYHSWLLVGSRTEVT-------QVNT------------------TNCGRLQ 517
Query: 524 ACQRSCLASQDPYCGW 539
+C C+ +QDP C W
Sbjct: 518 SCS-ECILAQDPVCAW 532
>gi|28872814 semaphorin 4G [Homo sapiens]
Length = 843
Score = 205 bits (521), Expect = 2e-52
Identities = 156/491 (31%), Positives = 235/491 (47%), Gaps = 55/491 (11%)
Query: 73 LLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQDV--ENCAVRGKLTD-ECYNYIRVLV 129
LLV AR +FS L A + G+G +K + W + C +GK EC+N++R L
Sbjct: 68 LLVGARGALFS--LSANDIGDGA--HKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQ 123
Query: 130 PWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAIFAEGSLYSA 189
+S L ACGT++F P+C + + G+ +CP+D + + +G LY+A
Sbjct: 124 RLNSTHLYACGTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTA 183
Query: 190 TAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFV----------QALEHGDHVYFF 239
T +F+ S + RS P LR+ + WL + FV A+ D VY+F
Sbjct: 184 TRYEFR-SIPDIRRSRHPH-SLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYF 241
Query: 240 FREVSVEDARLGRVQ------FSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDS 293
F E + E+ Q +RVARVCK D+GG + L + WTSFLK RL C +P
Sbjct: 242 FTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGK-KILQKKWTSFLKARLICHIP--- 297
Query: 294 TFYFDVLQALTGPVNLHGRSALFGVFT--TQTNSIPGSAVCAFYLDEIERGFEGKFKEQR 351
Y + + R+ + FT TQ ++ SA+C + L EI+ F G + E +
Sbjct: 298 -LYETLRGVCSLDAETSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQ 356
Query: 352 SLDGAWTPVSEDRVPSPRPGSCAGVG-GAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVT 410
W E VP PRPGSC + ++SS+DLP VL F+K HPL+ V P
Sbjct: 357 DGSRRWGRY-EGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTR 415
Query: 411 HQPLLTLTS--RALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILL 468
+PLL + LT V AGP ++FLG+ DG + K + G ++
Sbjct: 416 GRPLLLKRNIRYTHLTGTPVTTPAGP--TYDLLFLGTADGWIHKAVVLGSGMH-----II 468
Query: 469 EEIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRS 528
EE + R +Q+ ++ + H L+V ++ LPLS C+R+ +C
Sbjct: 469 EETQVF--------RESQSVENLV---ISLLQHSLYVGAPSGVIQLPLSSCSRYRSCY-D 516
Query: 529 CLASQDPYCGW 539
C+ ++DPYCGW
Sbjct: 517 CILARDPYCGW 527
>gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens]
Length = 652
Score = 131 bits (330), Expect = 3e-30
Identities = 125/453 (27%), Positives = 195/453 (43%), Gaps = 56/453 (12%)
Query: 109 ENCAVRGKLTDECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQAR 168
+N +VR +C NYI L+ S+ LLACGTN+ P C + ++ GE + G A
Sbjct: 104 KNASVR----TDCENYI-TLLERRSEGLLACGTNARHPSCWNLVNGTVVPLGE-MRGYA- 156
Query: 169 CPFDATQSNVAIFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQ 228
PF ++++ +F +YS +R + + L ++ ++ P F++
Sbjct: 157 -PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTS---DTVMQNPQFIK 212
Query: 229 AL------EHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLK 282
A + D +Y+FFRE + + + SRVA++C+ D GG W +FLK
Sbjct: 213 ATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLK 272
Query: 283 LRLNCSVPGDSTFYFDVLQ---ALTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEI 339
L CS + F+ LQ L P + ++GVF+ N SAVC + L +I
Sbjct: 273 AMLVCSDAATNK-NFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDI 328
Query: 340 ERGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAH 399
++ F SL G +P+PRPG C + +P + H
Sbjct: 329 DKVFRTS-----SLKGY-----HSSLPNPRPGKC--------LPDQQPIPTETFQVADRH 370
Query: 400 PLLDPAVPPVTHQPLLTLTSRALLTQVAVDGMAGPHSN-ITVMFLGSNDGTVLKVLTPGG 458
P + V P+ S+ +VAV M H V++L ++ GT+ KV+ PG
Sbjct: 371 PEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGE 430
Query: 459 RSGGPEPILLEEIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSR 518
+ E I P R A I + LD E +L+V+ + +PL
Sbjct: 431 Q----EHSFAFNIMEIQPFR--------RAAAIQTMSLDAERRKLYVSSQWEVSQVPLDL 478
Query: 519 CARHGACQRSCLASQDPYCGWHSSRGCVDIRGS 551
C +G CL S+DPYCGW R C+ I S
Sbjct: 479 CEVYGGGCHGCLMSRDPYCGWDQGR-CISIYSS 510
>gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens]
Length = 666
Score = 131 bits (329), Expect = 3e-30
Identities = 122/442 (27%), Positives = 190/442 (42%), Gaps = 52/442 (11%)
Query: 120 ECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVA 179
+C NYI L+ S+ LLACGTN+ P C + ++ GE + G A PF ++++
Sbjct: 125 DCENYI-TLLERRSEGLLACGTNARHPSCWNLVNGTVVPLGE-MRGYA--PFSPDENSLV 180
Query: 180 IFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQAL------EHG 233
+F +YS +R + + L ++ ++ P F++A +
Sbjct: 181 LFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTS---DTVMQNPQFIKATIVHQDQAYD 237
Query: 234 DHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDS 293
D +Y+FFRE + + + SRVA++C+ D GG W +FLK L CS +
Sbjct: 238 DKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATN 297
Query: 294 TFYFDVLQ---ALTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQ 350
F+ LQ L P + ++GVF+ N SAVC + L +I++ F
Sbjct: 298 K-NFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVFRTS---- 349
Query: 351 RSLDGAWTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVT 410
SL G +P+PRPG C + +P + HP + V P+
Sbjct: 350 -SLKGY-----HSSLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVAQRVEPMG 395
Query: 411 HQPLLTLTSRALLTQVAVDGMAGPHSN-ITVMFLGSNDGTVLKVLTPGGRSGGPEPILLE 469
S+ +VAV M H V++L ++ GT+ KV+ PG + E
Sbjct: 396 PLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQ----EHSFAF 451
Query: 470 EIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSC 529
I P R A I + LD E +L+V+ + +PL C +G C
Sbjct: 452 NIMEIQPFR--------RAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGC 503
Query: 530 LASQDPYCGWHSSRGCVDIRGS 551
L S+DPYCGW R C+ I S
Sbjct: 504 LMSRDPYCGWDQGR-CISIYSS 524
>gi|225637524 semaphorin 7A isoform 3 [Homo sapiens]
Length = 501
Score = 113 bits (282), Expect = 9e-25
Identities = 103/392 (26%), Positives = 163/392 (41%), Gaps = 48/392 (12%)
Query: 170 PFDATQSNVAIFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQA 229
PF ++++ +F +YS +R + + L ++ ++ P F++A
Sbjct: 6 PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTS---DTVMQNPQFIKA 62
Query: 230 L------EHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKL 283
+ D +Y+FFRE + + + SRVA++C+ D GG W +FLK
Sbjct: 63 TIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKA 122
Query: 284 RLNCSVPGDSTFYFDVLQ---ALTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIE 340
L CS + F+ LQ L P + ++GVF+ N SAVC + L +I+
Sbjct: 123 MLVCSDAATNK-NFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDID 178
Query: 341 RGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHP 400
+ F SL G +P+PRPG C + +P + HP
Sbjct: 179 KVFRTS-----SLKGY-----HSSLPNPRPGKC--------LPDQQPIPTETFQVADRHP 220
Query: 401 LLDPAVPPVTHQPLLTLTSRALLTQVAVDGMAGPHSN-ITVMFLGSNDGTVLKVLTPGGR 459
+ V P+ S+ +VAV M H V++L ++ GT+ KV+ PG +
Sbjct: 221 EVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQ 280
Query: 460 SGGPEPILLEEIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRC 519
E I P R A I + LD E +L+V+ + +PL C
Sbjct: 281 ----EHSFAFNIMEIQPFR--------RAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLC 328
Query: 520 ARHGACQRSCLASQDPYCGWHSSRGCVDIRGS 551
+G CL S+DPYCGW R C+ I S
Sbjct: 329 EVYGGGCHGCLMSRDPYCGWDQGR-CISIYSS 359
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.137 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,749,005
Number of Sequences: 37866
Number of extensions: 3079387
Number of successful extensions: 20659
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 142
Number of HSP's successfully gapped in prelim test: 1185
Number of HSP's that attempted gapping in prelim test: 13538
Number of HSP's gapped (non-prelim): 5256
length of query: 930
length of database: 18,247,518
effective HSP length: 112
effective length of query: 818
effective length of database: 14,006,526
effective search space: 11457338268
effective search space used: 11457338268
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.