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Search of human proteins with 160707881
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|160707881 formin 2 [Homo sapiens]
(1722 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|160707881 formin 2 [Homo sapiens] 3553 0.0
gi|157168329 formin 1 [Homo sapiens] 556 e-158
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 317 8e-86
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 317 8e-86
gi|163965366 nascent polypeptide-associated complex alpha subuni... 196 2e-49
gi|47132519 Ras association and pleckstrin homology domains 1 is... 191 7e-48
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 191 7e-48
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 191 7e-48
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 182 2e-45
gi|33356148 formin-like 1 [Homo sapiens] 182 2e-45
gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] 180 1e-44
gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] 180 1e-44
gi|21071077 dishevelled-associated activator of morphogenesis 1 ... 177 8e-44
gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens] 177 1e-43
gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens] 177 1e-43
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 168 5e-41
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 168 5e-41
gi|40548415 dishevelled associated activator of morphogenesis 2 ... 167 8e-41
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 167 1e-40
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 166 1e-40
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] 164 7e-40
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] 164 7e-40
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 162 3e-39
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 156 2e-37
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 156 2e-37
gi|52485606 formin-like 2 [Homo sapiens] 155 3e-37
gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 155 4e-37
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 155 4e-37
gi|116284392 mucin 2 precursor [Homo sapiens] 154 9e-37
gi|150417989 cyclin K isoform 1 [Homo sapiens] 148 5e-35
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 3553 bits (9212), Expect = 0.0
Identities = 1722/1722 (100%), Positives = 1722/1722 (100%)
Query: 1 MGNQDGKLKRSAGDALHEGGGGAEDALGPRDVEATKKGSGGKKALGKHGKGGGGGGGGGE 60
MGNQDGKLKRSAGDALHEGGGGAEDALGPRDVEATKKGSGGKKALGKHGKGGGGGGGGGE
Sbjct: 1 MGNQDGKLKRSAGDALHEGGGGAEDALGPRDVEATKKGSGGKKALGKHGKGGGGGGGGGE 60
Query: 61 SGKKKSKSDSRASVFSNLRIRKNLSKGKGAGGSREDVLDSQALQTGELDSAHSLLTKTPD 120
SGKKKSKSDSRASVFSNLRIRKNLSKGKGAGGSREDVLDSQALQTGELDSAHSLLTKTPD
Sbjct: 61 SGKKKSKSDSRASVFSNLRIRKNLSKGKGAGGSREDVLDSQALQTGELDSAHSLLTKTPD 120
Query: 121 LSLSADEAGLSDTECADPFEVTGPGGPGPAEARVGGRPIAEDVETAAGAQDGQRTSSGSD 180
LSLSADEAGLSDTECADPFEVTGPGGPGPAEARVGGRPIAEDVETAAGAQDGQRTSSGSD
Sbjct: 121 LSLSADEAGLSDTECADPFEVTGPGGPGPAEARVGGRPIAEDVETAAGAQDGQRTSSGSD 180
Query: 181 TDIYSFHSATEQEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVS 240
TDIYSFHSATEQEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVS
Sbjct: 181 TDIYSFHSATEQEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVS 240
Query: 241 PQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLP 300
PQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLP
Sbjct: 241 PQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLP 300
Query: 301 VSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRG 360
VSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRG
Sbjct: 301 VSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRG 360
Query: 361 SPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIK 420
SPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIK
Sbjct: 361 SPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIK 420
Query: 421 TTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLAAGLS 480
TTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLAAGLS
Sbjct: 421 TTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLAAGLS 480
Query: 481 RSADWTEELGARTPRVGGSAHLLERGVASDSGGGVSPALAAKASGAPAAADGFQNVFTGR 540
RSADWTEELGARTPRVGGSAHLLERGVASDSGGGVSPALAAKASGAPAAADGFQNVFTGR
Sbjct: 481 RSADWTEELGARTPRVGGSAHLLERGVASDSGGGVSPALAAKASGAPAAADGFQNVFTGR 540
Query: 541 TLLEKLFSQQENGPPEEAEKFCSRIIAMGLLLPFSDCFREPCNQNAQTNAASFDQDQLYT 600
TLLEKLFSQQENGPPEEAEKFCSRIIAMGLLLPFSDCFREPCNQNAQTNAASFDQDQLYT
Sbjct: 541 TLLEKLFSQQENGPPEEAEKFCSRIIAMGLLLPFSDCFREPCNQNAQTNAASFDQDQLYT 600
Query: 601 WAAVSQPTHSLDYSEGQFPRRVPSMGPPSKPPDEEHRLEDAETESQSAVSETPQKRSDAV 660
WAAVSQPTHSLDYSEGQFPRRVPSMGPPSKPPDEEHRLEDAETESQSAVSETPQKRSDAV
Sbjct: 601 WAAVSQPTHSLDYSEGQFPRRVPSMGPPSKPPDEEHRLEDAETESQSAVSETPQKRSDAV 660
Query: 661 QKEVVDMKSEGQATVIQQLEQTIEDLRTKIAELERQYPALDTEVASGHQGLENGVTASGD 720
QKEVVDMKSEGQATVIQQLEQTIEDLRTKIAELERQYPALDTEVASGHQGLENGVTASGD
Sbjct: 661 QKEVVDMKSEGQATVIQQLEQTIEDLRTKIAELERQYPALDTEVASGHQGLENGVTASGD 720
Query: 721 VCLEALRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTK 780
VCLEALRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTK
Sbjct: 721 VCLEALRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTK 780
Query: 781 FCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTS 840
FCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTS
Sbjct: 781 FCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTS 840
Query: 841 HEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPP 900
HEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPP
Sbjct: 841 HEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPP 900
Query: 901 PLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLP 960
PLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLP
Sbjct: 901 PLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLP 960
Query: 961 GAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1020
GAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP
Sbjct: 961 GAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1020
Query: 1021 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1080
PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL
Sbjct: 1021 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1080
Query: 1081 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1140
PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI
Sbjct: 1081 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1140
Query: 1141 PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP 1200
PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP
Sbjct: 1141 PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP 1200
Query: 1201 LPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVC 1260
LPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVC
Sbjct: 1201 LPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVC 1260
Query: 1261 GFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSSTSLIWEKIEE 1320
GFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSSTSLIWEKIEE
Sbjct: 1261 GFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSSTSLIWEKIEE 1320
Query: 1321 PSIDCHEFEELFSKTAVKERKKPISDTISKTKAKQVVKLLSNKRSQAVGILMSSLHLDMK 1380
PSIDCHEFEELFSKTAVKERKKPISDTISKTKAKQVVKLLSNKRSQAVGILMSSLHLDMK
Sbjct: 1321 PSIDCHEFEELFSKTAVKERKKPISDTISKTKAKQVVKLLSNKRSQAVGILMSSLHLDMK 1380
Query: 1381 DIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIEKHGRSSKDKENAKSLDKPEQFLYE 1440
DIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIEKHGRSSKDKENAKSLDKPEQFLYE
Sbjct: 1381 DIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIEKHGRSSKDKENAKSLDKPEQFLYE 1440
Query: 1441 LSLIPNFSERVFCILFQSTFSESICSIRRKLELLQKLCETLKNGPGVMQVLGLVLAFGNY 1500
LSLIPNFSERVFCILFQSTFSESICSIRRKLELLQKLCETLKNGPGVMQVLGLVLAFGNY
Sbjct: 1441 LSLIPNFSERVFCILFQSTFSESICSIRRKLELLQKLCETLKNGPGVMQVLGLVLAFGNY 1500
Query: 1501 MNGGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLSYIVSYYLRNFDEDAGKEQCLFPLP 1560
MNGGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLSYIVSYYLRNFDEDAGKEQCLFPLP
Sbjct: 1501 MNGGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLSYIVSYYLRNFDEDAGKEQCLFPLP 1560
Query: 1561 EPQDLFQASQMKFEDFQKDLRKLKKDLKACEVEAGKVYQVSSKEHMQPFKENMEQFIIQA 1620
EPQDLFQASQMKFEDFQKDLRKLKKDLKACEVEAGKVYQVSSKEHMQPFKENMEQFIIQA
Sbjct: 1561 EPQDLFQASQMKFEDFQKDLRKLKKDLKACEVEAGKVYQVSSKEHMQPFKENMEQFIIQA 1620
Query: 1621 KIDQEAEENSLTETHKCFLETTAYFFMKPKLGEKEVSPNAFFSIWHEFSSDFKDFWKKEN 1680
KIDQEAEENSLTETHKCFLETTAYFFMKPKLGEKEVSPNAFFSIWHEFSSDFKDFWKKEN
Sbjct: 1621 KIDQEAEENSLTETHKCFLETTAYFFMKPKLGEKEVSPNAFFSIWHEFSSDFKDFWKKEN 1680
Query: 1681 KLLLQERVKEAEEVCRQKKGKSLYKIKPRHDSGIKAKISMKT 1722
KLLLQERVKEAEEVCRQKKGKSLYKIKPRHDSGIKAKISMKT
Sbjct: 1681 KLLLQERVKEAEEVCRQKKGKSLYKIKPRHDSGIKAKISMKT 1722
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 556 bits (1432), Expect = e-158
Identities = 294/576 (51%), Positives = 380/576 (65%), Gaps = 36/576 (6%)
Query: 1151 IPPPPPLPGAGIPPPPPLPGA--GIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPP 1208
+PPPP A IPPPPPLP + P PP+P V PP P PPPPP PP
Sbjct: 645 LPPPP----ASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLP------PPPPP------PP 688
Query: 1209 PPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
P P P PP P PP P P + PP P GPP P P G PPP P
Sbjct: 689 PLPPPSSAGPPPPPPPPPLPNSPAPPNP----GGPP----------PAPPPPGLAPPPPP 734
Query: 1269 SGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSSTSLIWEKIEEPSI-DCHE 1327
FGLG + + RK IEP PMKPLYWTRIQ+ + ++T +W+ +EEP I D E
Sbjct: 735 GLFFGLGSSSSQCPRKPAIEPSCPMKPLYWTRIQISDRSQNATPTLWDSLEEPDIRDPSE 794
Query: 1328 FEELFSKTAVKERKKPISDTISK-TKAKQVVKLLSNKRSQAVGILMSSLHLDMKDIQHAV 1386
FE LFSK +++KKP+S+T K K K+++KLL KRSQ VGIL+SSLHL+MKDIQ A+
Sbjct: 795 FEYLFSKDTTQQKKKPLSETYEKKNKVKKIIKLLDGKRSQTVGILISSLHLEMKDIQQAI 854
Query: 1387 VNLDNSVVDLETLQALYENRAQSDELEKIEKHGRSSKDKENAKSLDKPEQFLYELSLIPN 1446
N+D+SVVDLETL ALYENRAQ DEL KI K+ +SK++E K LDKPEQFL+EL+ IPN
Sbjct: 855 FNVDDSVVDLETLAALYENRAQEDELVKIRKYYETSKEEE-LKLLDKPEQFLHELAQIPN 913
Query: 1447 FSERVFCILFQSTFSESICSIRRKLELLQKLCETLKNGPGVMQVLGLVLAFGNYMNGGNK 1506
F+ER CI+F+S FSE I S+ RK+E++ + + L + V +L L+LAFGNYMNGGN+
Sbjct: 914 FAERAQCIIFRSVFSEGITSLHRKVEIITRASKDLLHVKSVKDILALILAFGNYMNGGNR 973
Query: 1507 TRGQADGFGLDILPKLKDVKSSDNSRSLLSYIVSYYLRNFDEDAGKEQCLFPLPEPQDLF 1566
TRGQADG+ L+ILPKLKDVKS DN +L+ Y+V YYLR +D++AG E+ +FPLPEPQD F
Sbjct: 974 TRGQADGYSLEILPKLKDVKSRDNGINLVDYVVKYYLRYYDQEAGTEKSVFPLPEPQDFF 1033
Query: 1567 QASQMKFEDFQKDLRKLKKDLKACEVEAGKVYQVSSKEHMQPFKENMEQFIIQAKIDQEA 1626
ASQ+KFED KDLRKLK+ L+A E + V + S KE++QPFK+ +E+F +AK + +
Sbjct: 1034 LASQVKFEDLIKDLRKLKRQLEASEKQMVVVCKESPKEYLQPFKDKLEEFFQKAKKEHKM 1093
Query: 1627 EENSLTETHKCFLETTAYFFMKPKLGEKEVSPNAFFSIWHEFSSDFKDFWKKENKLLLQE 1686
EE+ L K F T YF MKPK GEKE++P+ F +W+EF SDFK WK+E+K + +E
Sbjct: 1094 EESHLENAQKSFETTVRYFGMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKE 1153
Query: 1687 RVKEAEE-VCRQKKGKSLYKIKPRHDSGIKAKISMK 1721
R+K A+E V + K + K + +K ++ K
Sbjct: 1154 RLKMAQESVSKLTSEKKVETKKINPTASLKERLRQK 1189
Score = 103 bits (256), Expect = 2e-21
Identities = 59/119 (49%), Positives = 65/119 (54%), Gaps = 29/119 (24%)
Query: 1074 IPPPPPLPGAGIPPPPPLPGA--GIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPP 1131
+PPPP A IPPPPPLP + P PP+P V PP +PPPPP P PP
Sbjct: 645 LPPPP----ASIPPPPPLPSGLGSLSPAPPMPPVSAGPP-------LPPPPPPP----PP 689
Query: 1132 PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL 1190
PP AG PPP PPPPPLP + P PP PG G PP PP PG+ PPPP L
Sbjct: 690 LPPPSSAGPPPP--------PPPPPLPNS---PAPPNPG-GPPPAPPPPGLAPPPPPGL 736
Score = 102 bits (253), Expect = 4e-21
Identities = 58/119 (48%), Positives = 63/119 (52%), Gaps = 29/119 (24%)
Query: 1008 IPPPPPLPGAGIPPPPPLPG--AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1065
+PPPP A IPPPPPLP + P PP+P PP P PPPPP PP
Sbjct: 645 LPPPP----ASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLP------PPPPP------PP 688
Query: 1066 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL 1124
P P P + PPPP PPPPPLP + P PP PG G PP PP PG PPPP L
Sbjct: 689 PLPPPSSAGPPPP-------PPPPPLPNS---PAPPNPG-GPPPAPPPPGLAPPPPPGL 736
Score = 101 bits (252), Expect = 5e-21
Identities = 66/160 (41%), Positives = 78/160 (48%), Gaps = 20/160 (12%)
Query: 882 PLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLP-GAGIPPPPPLPGAGILPLPPLPGA 940
P + T + +P+ + L PP A + P + LPP P A
Sbjct: 592 PCESESKTTRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPP-PPA 650
Query: 941 GIPPPPPLPG--AAIPPPPPLP--GAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 996
IPPPPPLP ++ P PP+P AG PLPPP P PPPP P + PPPP
Sbjct: 651 SIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPP----PPPPLPPPSSAGPPPP----- 701
Query: 997 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1036
PPPPPLP + P PP PG G PP PP PG PPPP L
Sbjct: 702 -PPPPPLPNS---PAPPNPG-GPPPAPPPPGLAPPPPPGL 736
Score = 100 bits (250), Expect = 9e-21
Identities = 58/119 (48%), Positives = 63/119 (52%), Gaps = 29/119 (24%)
Query: 975 IPPPPPLPGAGIPPPPPLPGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1032
+PPPP A IPPPPPLP + P PP+P PP +PPPPP P PP
Sbjct: 645 LPPPP----ASIPPPPPLPSGLGSLSPAPPMPPVSAGPP-------LPPPPPPP----PP 689
Query: 1033 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1091
PP AG PPP PPPPPLP + P PP PG G PP PP PG PPPP L
Sbjct: 690 LPPPSSAGPPPP--------PPPPPLPNS---PAPPNPG-GPPPAPPPPGLAPPPPPGL 736
Score = 100 bits (250), Expect = 9e-21
Identities = 58/119 (48%), Positives = 63/119 (52%), Gaps = 29/119 (24%)
Query: 986 IPPPPPLPGAGIPPPPPLPGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1043
+PPPP A IPPPPPLP + P PP+P PP +PPPPP P PP
Sbjct: 645 LPPPP----ASIPPPPPLPSGLGSLSPAPPMPPVSAGPP-------LPPPPPPP----PP 689
Query: 1044 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1102
PP AG PPP PPPPPLP + P PP PG G PP PP PG PPPP L
Sbjct: 690 LPPPSSAGPPPP--------PPPPPLPNS---PAPPNPG-GPPPAPPPPGLAPPPPPGL 736
Score = 100 bits (250), Expect = 9e-21
Identities = 58/119 (48%), Positives = 63/119 (52%), Gaps = 29/119 (24%)
Query: 1030 IPPPPPLPGAGIPPPPPLPGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1087
+PPPP A IPPPPPLP + P PP+P PP +PPPPP P PP
Sbjct: 645 LPPPP----ASIPPPPPLPSGLGSLSPAPPMPPVSAGPP-------LPPPPPPP----PP 689
Query: 1088 PPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1146
PP AG PPP PPPPPLP + P PP PG G PP PP PG PPPP L
Sbjct: 690 LPPPSSAGPPPP--------PPPPPLPNS---PAPPNPG-GPPPAPPPPGLAPPPPPGL 736
Score = 100 bits (248), Expect = 2e-20
Identities = 60/118 (50%), Positives = 64/118 (54%), Gaps = 27/118 (22%)
Query: 942 IPPPPPLPGAAIPPPPPLP-GAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1000
+PPPP A+IPPPPPLP G G P P P PP G +PPPPP P PP
Sbjct: 645 LPPPP----ASIPPPPPLPSGLGSLSPAP------PMPPVSAGPPLPPPPPPP----PPL 690
Query: 1001 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1058
PP AG PPP PPPPPLP + P PP PG G PP PP PG PPPP L
Sbjct: 691 PPPSSAGPPPP--------PPPPPLPNS---PAPPNPG-GPPPAPPPPGLAPPPPPGL 736
Score = 100 bits (248), Expect = 2e-20
Identities = 58/117 (49%), Positives = 62/117 (52%), Gaps = 27/117 (23%)
Query: 966 LPPPLPGAGIPPPPPLPG--AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1023
LPPP A IPPPPPLP + P PP+P PP P PPPPP PPP
Sbjct: 645 LPPP--PASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLP------PPPPP------PPPL 690
Query: 1024 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1080
P P + PPPP PPPPPLP + P PP PG G PP PP PG PPPP L
Sbjct: 691 PPPSSAGPPPP-------PPPPPLPNS---PAPPNPG-GPPPAPPPPGLAPPPPPGL 736
Score = 99.0 bits (245), Expect = 4e-20
Identities = 56/119 (47%), Positives = 61/119 (51%), Gaps = 29/119 (24%)
Query: 1052 IPPPPPLPGAGIPPPPPLPGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP 1109
+PPPP A IPPPPPLP + P PP+P PP +PPPPP P PP
Sbjct: 645 LPPPP----ASIPPPPPLPSGLGSLSPAPPMPPVSAGPP-------LPPPPPPP----PP 689
Query: 1110 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPL 1168
PP AG PPP PPPPPLP + PP P G PP PP PG PPPP L
Sbjct: 690 LPPPSSAGPPPP--------PPPPPLPNSPAPPNPG----GPPPAPPPPGLAPPPPPGL 736
Score = 90.1 bits (222), Expect = 2e-17
Identities = 94/339 (27%), Positives = 134/339 (39%), Gaps = 53/339 (15%)
Query: 623 PSMGPP-SKPPDEEHRLEDAETESQSAVSETPQKRSDAVQKEVVDM-KSEGQATVIQQLE 680
P+ GP SK PD +D T + P K D +K + ++E QA ++
Sbjct: 449 PADGPSDSKSPDHSLTEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKR 508
Query: 681 QTIEDLRTKIAELERQYPALDTEVASGHQGLENGVTASGDVCLEALRLEEKEVRHHRILE 740
+ E++ A+ E + A +G +TA + +E L+ E + E
Sbjct: 509 EHKEEIENLQAQFELR--------AFHIRGEHAMITARLEETIENLKHELEHRWRGGCEE 560
Query: 741 AKSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDS 800
K + S ++ T V R ES +T +++ P+++++
Sbjct: 561 RKDVCISTDDDCPPKTFRNVCVQTDRETFLKPCESESKTTRSNQLV----PKKLNIS--- 613
Query: 801 HQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPP 860
S+SQ PP + H+ + + + +IP PPP
Sbjct: 614 -----SLSQLSPPND-----------HKDIHAALQPMEGMASNQQKALPPPPASIPPPPP 657
Query: 861 LPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGI 920
LP GLG + P PP P P LP P PPP PPP PP AG
Sbjct: 658 LPS--------GLGSLSPAPPMPPVSAGPPLP----PPPPP-------PPPLPPPSSAGP 698
Query: 921 PPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPL 959
PPPPP P P PP PG G PP PP PG A PPPP L
Sbjct: 699 PPPPPPPPLPNSPAPPNPG-GPPPAPPPPGLAPPPPPGL 736
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 317 bits (811), Expect = 8e-86
Identities = 245/703 (34%), Positives = 339/703 (48%), Gaps = 129/703 (18%)
Query: 1025 LPGAGIPPPPPLPG-AGIPPPPPLPGAG--IPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1081
L A I PP +P A +PP PPLPG I PPPP PG PPPP PPPP
Sbjct: 556 LSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPP-------PPPP-- 606
Query: 1082 GAGIPPPPPLPGAG-IPPPPPLPG-VGIPPPPPLPG-AGIPPPPPLP-GAGIPPPPPLP- 1136
PPPPPLPG I PP LPG I PPPPL G A IPPPPPLP G GIP P LP
Sbjct: 607 ----PPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG 662
Query: 1137 GAGIPPPPPLPRVG--IPPPPPLPG-AGI-PPPPPLPG-AGIPPPPPLPGVGIPPPPPLP 1191
G IPPPPPLP PPPPPLPG AGI PPPPPLPG AG+P PPPPPLP
Sbjct: 663 GTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMP----------PPPPPLP 712
Query: 1192 -GVGIPPPPPLPGA-GIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQV 1249
G GIPPPPP PG GIPPPP PGMG+PP PP G G+P P+LP
Sbjct: 713 GGPGIPPPPPFPGGPGIPPPP--PGMGMPPP-----PPFGFGVPAAPVLP---------- 755
Query: 1250 GSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDS 1309
FGL + K+ +P ++ W+++ D
Sbjct: 756 ----------------------FGL-------TPKKLYKPEVQLRRPNWSKL---VAEDL 783
Query: 1310 STSLIWEKIEEPSIDCHEFEELFSK--------TAVKERKK-----PISDTISKTKAKQV 1356
S W K++E D E ELF+K T + KK ++ K K K+
Sbjct: 784 SQDCFWTKVKE---DRFENNELFAKLTLTFSAQTKTSKAKKDQEGGEEKKSVQKKKVKE- 839
Query: 1357 VKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIE 1416
+K+L +K +Q + I + S + ++I++ ++ ++ +V+ +Q L + + ++L+ +
Sbjct: 840 LKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKML- 898
Query: 1417 KHGRSSKDKENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQK 1476
S+ K+ L + EQF + +P R+ ILF+ FSE + +I+ ++ +
Sbjct: 899 -----SELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTA 953
Query: 1477 LCETLKNGPGVMQVLGLVLAFGNYMNGGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLS 1536
CE L+ +L + L GNYMN G++ G A GF + L KL+D KS+D +LL
Sbjct: 954 ACEELRKSESFSNLLEITLLVGNYMNAGSRNAG-AFGFNISFLCKLRDTKSTDQKMTLL- 1011
Query: 1537 YIVSYYLRNFDEDAGKEQCLFPLPEPQDLFQASQMKFEDFQKDLRKLKKDLKACEVEAGK 1596
++L E+ + FP E + +AS++ E+ QK+L ++KK + +VE
Sbjct: 1012 ----HFLAELCENDYPDVLKFP-DELAHVEKASRVSAENLQKNLDQMKKQIS--DVERDV 1064
Query: 1597 VYQVSSKEHMQPFKENMEQFIIQAKIDQEAEENSLTETHKCFLETTAYFFMKPKLGEKEV 1656
++ + F E M F+ A+ + + E YF P K++
Sbjct: 1065 QNFPAATDEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDP----KKL 1120
Query: 1657 SPNAFFSIWHEFSSDFKDFWKKENKLLLQERVKEAEEVCRQKK 1699
S FF H F + F K+ K +E EE R+ K
Sbjct: 1121 SVEEFFMDLHNFRNMFLQAVKENQKR------RETEEKMRRAK 1157
Score = 224 bits (572), Expect = 4e-58
Identities = 133/211 (63%), Positives = 141/211 (66%), Gaps = 22/211 (10%)
Query: 959 LPGAGIPLPPPLPG-AGIPPPPPLPGAG--IPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1015
L A I +PP +P A +PP PPLPG I PPPP PG PPPP P PPPPPLP
Sbjct: 556 LSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP--PPPPPLP 613
Query: 1016 GAG-IPPPPPLPGA-GIPPPPPLPG-AGIPPPPPLP-GAGIPPPPPLP-GAGIPPPPPLP 1070
G I PP LPG I PPPPL G A IPPPPPLP G GIP P LP G IPPPPPLP
Sbjct: 614 GGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLP 673
Query: 1071 GAG--IPPPPPLPG-AGI-PPPPPLPG-AGI-PPPPPLP-GVGIPPPPPLPGA-GIPPPP 1122
G+ PPPPPLPG AGI PPPPPLPG AG+ PPPPPLP G GIPPPPP PG GIPPPP
Sbjct: 674 GSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPP 733
Query: 1123 PLPGAGIPPPPPLPGAGIPPPPPLPRVGIPP 1153
PG G+PPPPP G G+P P LP G+ P
Sbjct: 734 --PGMGMPPPPPF-GFGVPAAPVLP-FGLTP 760
Score = 223 bits (567), Expect = 2e-57
Identities = 138/235 (58%), Positives = 145/235 (61%), Gaps = 34/235 (14%)
Query: 937 LPGAGIPPPPPLPGAA-IPPPPPLPGAG---IPLPPPLPGAGIPPPPPLPGAGIPPPPPL 992
L A I PP +P A +PP PPLPG IP PPP PG PPPP PPPP
Sbjct: 556 LSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIP-PPPAPGDSTTPPPP-------PPPP- 606
Query: 993 PGAGIPPPPPLPGAG-IPPPPPLPGA-GIPPPPPLPG-AGIPPPPPLP-GAGIPPPPPLP 1048
PPPPPLPG I PP LPG I PPPPL G A IPPPPPLP G GIP P LP
Sbjct: 607 -----PPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLP 661
Query: 1049 GA-GIPPPPPLPGAGI--PPPPPLPG-AGIPPPPP-LPG-AGIPPPPP-LPGA-GIPPPP 1100
G IPPPPPLPG+ PPPPPLPG AGIPPPPP LPG AG+PPPPP LPG GIPPPP
Sbjct: 662 GGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPP 721
Query: 1101 PLPG-VGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPP 1154
P PG GIPPPPP G G+PPPPP G G+P P LP P P V + P
Sbjct: 722 PFPGGPGIPPPPP--GMGMPPPPPF-GFGVPAAPVLPFGLTPKKLYKPEVQLRRP 773
Score = 218 bits (555), Expect = 4e-56
Identities = 130/213 (61%), Positives = 138/213 (64%), Gaps = 31/213 (14%)
Query: 912 PPPLPG-AGIPPPPPLPGAG--ILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP 968
PP +P A +PP PPLPG I+P PP PG PPPP P PPPPPLPG
Sbjct: 564 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP--PPPPPLPG------- 614
Query: 969 PLPGAGIPPPPPLPGA-GIPPPPPLPG-AGIPPPPPLP-GAGIPPPPPLP-GAGIPPPPP 1024
G I PP LPG I PPPPL G A IPPPPPLP G GIP P LP G IPPPPP
Sbjct: 615 ---GVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPP 671
Query: 1025 LPGAG--IPPPPPLPG-AGI-PPPPPLPG-AGI-PPPPPLPGA-GIPPPPPLPGA-GIPP 1076
LPG+ PPPPPLPG AGI PPPPPLPG AG+ PPPPPLPG GIPPPPP PG GIPP
Sbjct: 672 LPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPP 731
Query: 1077 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP 1109
PP PG G+PPPPP G G+P P LP G+ P
Sbjct: 732 PP--PGMGMPPPPPF-GFGVPAAPVLP-FGLTP 760
Score = 212 bits (539), Expect = 3e-54
Identities = 127/207 (61%), Positives = 135/207 (65%), Gaps = 21/207 (10%)
Query: 890 TLPSTAIPQPPPLQGTEMLPPPPPPLPGAG--IPPPPPLPGAGILPLPPLPGAGIPPPPP 947
+L + AI PP + +PP PP LPG I PPPP PG P PP P PPPPP
Sbjct: 555 SLSAAAITVPPSVPSRAPVPPAPP-LPGDSGTIIPPPPAPGDSTTPPPPPPPP--PPPPP 611
Query: 948 LPGAA-IPPPPPLPGA-GIPLPPPLPG-AGIPPPPPLP-GAGIPPPPPLP-GAGIPPPPP 1002
LPG I PP LPG I PPPL G A IPPPPPLP G GIP P LP G IPPPPP
Sbjct: 612 LPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPP 671
Query: 1003 LPGAG--IPPPPPLPG-AGI-PPPPPLPG-AGI-PPPPPLPGA-GIPPPPPLPGA-GIPP 1054
LPG+ PPPPPLPG AGI PPPPPLPG AG+ PPPPPLPG GIPPPPP PG GIPP
Sbjct: 672 LPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPP 731
Query: 1055 PPPLPGAGIPPPPPLPGAGIPPPPPLP 1081
PP PG G+PPPPP G G+P P LP
Sbjct: 732 PP--PGMGMPPPPPF-GFGVPAAPVLP 755
Score = 184 bits (467), Expect = 6e-46
Identities = 108/196 (55%), Positives = 115/196 (58%), Gaps = 26/196 (13%)
Query: 855 IPSPPPLPCTESS----SSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPP 910
+P PPLP + PG PPPPPP P P I PP L G + P
Sbjct: 573 VPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISP 632
Query: 911 PPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLP-GAAIPPPPPLPGAG--IPLP 967
PPP A IPPPPPLP G GIP P LP G AIPPPPPLPG+ P P
Sbjct: 633 PPPLSGDATIPPPPPLP----------EGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 682
Query: 968 PPLPG-AGI-PPPPPLPG-AGI-PPPPPLPGA-GIPPPPPLPGA-GIPPPPPLPGAGIPP 1021
PPLPG AGI PPPPPLPG AG+ PPPPPLPG GIPPPPP PG GIPPPP PG G+PP
Sbjct: 683 PPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPP--PGMGMPP 740
Query: 1022 PPPLPGAGIPPPPPLP 1037
PPP G G+P P LP
Sbjct: 741 PPPF-GFGVPAAPVLP 755
Score = 128 bits (321), Expect = 5e-29
Identities = 119/363 (32%), Positives = 158/363 (43%), Gaps = 71/363 (19%)
Query: 632 PDEEHRLEDAETES--QSAVSETPQKRSDAVQKEVVDMKSEGQATVIQQLEQTIE----D 685
PD + R E E + +T ++S+A E+ + K + + T +L+ ++ D
Sbjct: 441 PDFKCRHLQIEIEGLIDQMIDKTKVEKSEAKAAEL-EKKLDSELTARHELQVEMKKMESD 499
Query: 686 LRTKIAELERQYPALDTE---VASGHQGLENGVTA-SGDVCLEALRLEEKEVRHHRILEA 741
K+ +L+ + AL +E +A+ Q LE V+ +G+V LE+ + E
Sbjct: 500 FEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKK------EM 553
Query: 742 KSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSH 801
S+ + +T+PP +P R P PP + I+ P DS
Sbjct: 554 ASLSAA------AITVPP--SVPSRAPVPPAPP------LPGDSGTIIPPP--PAPGDST 597
Query: 802 QPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPL 861
P PPPPP L P S P + S IP PPPL
Sbjct: 598 TPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAI---------SPPPPLSGDATIPPPPPL 648
Query: 862 P---CTESSSSMPGLGMVPPPPPPLPGMT-----VPTLPSTA--IPQPPPLQGTEMLPPP 911
P S SS+PG G PPPPPLPG P LP +A P PPPL G +PPP
Sbjct: 649 PEGVGIPSPSSLPG-GTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPP 707
Query: 912 PPPLP---GAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP 968
PPP G GIPPPPP PG G GIPPPP PG +PPPPP G G+P P
Sbjct: 708 PPP--LPGGPGIPPPPPFPG----------GPGIPPPP--PGMGMPPPPPF-GFGVPAAP 752
Query: 969 PLP 971
LP
Sbjct: 753 VLP 755
Score = 46.6 bits (109), Expect = 2e-04
Identities = 70/316 (22%), Positives = 101/316 (31%), Gaps = 70/316 (22%)
Query: 629 SKPPDEEHRLEDAETESQSAVSETPQKRSDAVQKEVVDMKSEGQATVIQQLEQTIEDLRT 688
+K + E +L+ T E + SD QK + D++ E A L + + T
Sbjct: 470 AKAAELEKKLDSELTARHELQVEMKKMESDFEQK-LQDLQGEKDA-----LHSEKQQIAT 523
Query: 689 KIAELERQYPALDTEVASGHQGLENGVTASGDVCLEALRLEEKEVRHHRILEAKSIQTSP 748
+ +LE + L EVA + LE+ + A+ + + A + P
Sbjct: 524 EKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPL---P 580
Query: 749 TEEGGVLTLPPVDGLPGRPPCPP-----------------------GAESGPQTKFCSEI 785
+ G ++ PP G PP PP G P +
Sbjct: 581 GDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDA 640
Query: 786 SLIVSP---RRISVQLDSHQP-----------TQSISQPPPPPSLLWSAG--------QG 823
++ P + + S P S PPPPP L SAG G
Sbjct: 641 TIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPG 700
Query: 824 QPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTES-SSSMPGLGMVPPPPPP 882
+ G PP IP PPP P PG+GM PPPP
Sbjct: 701 EAGMPPP---------------PPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFG 745
Query: 883 LPGMTVPTLPSTAIPQ 898
P LP P+
Sbjct: 746 FGVPAAPVLPFGLTPK 761
Score = 44.3 bits (103), Expect = 0.001
Identities = 54/217 (24%), Positives = 73/217 (33%), Gaps = 30/217 (13%)
Query: 189 ATEQEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVS--PQPGAF 246
ATE++DL +++ Q + +L +L+ +++ A PP+ S P P A
Sbjct: 522 ATEKQDLEAEVSQLTG----EVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPA- 576
Query: 247 LGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPS 306
L G SG P +P D P P PP PGG+ +S PS
Sbjct: 577 ----PPLPGDSGTIIPPPPAP---------GDSTTPPPPPPPPPPPPPLPGGVCISSPPS 623
Query: 307 LPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEW 366
LP + P S P P E G P + P PG
Sbjct: 624 LPGGTAISPPPPLSGDATIPPPPPLPEGVGIP------SPSSLPGGTAIPPPPPLPGSAR 677
Query: 367 APEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAP 403
P P G P P P A +P P P
Sbjct: 678 IPPPPPPLPGSAGIPPPP----PPLPGEAGMPPPPPP 710
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 317 bits (811), Expect = 8e-86
Identities = 245/703 (34%), Positives = 339/703 (48%), Gaps = 129/703 (18%)
Query: 1025 LPGAGIPPPPPLPG-AGIPPPPPLPGAG--IPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1081
L A I PP +P A +PP PPLPG I PPPP PG PPPP PPPP
Sbjct: 565 LSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPP-------PPPP-- 615
Query: 1082 GAGIPPPPPLPGAG-IPPPPPLPG-VGIPPPPPLPG-AGIPPPPPLP-GAGIPPPPPLP- 1136
PPPPPLPG I PP LPG I PPPPL G A IPPPPPLP G GIP P LP
Sbjct: 616 ----PPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG 671
Query: 1137 GAGIPPPPPLPRVG--IPPPPPLPG-AGI-PPPPPLPG-AGIPPPPPLPGVGIPPPPPLP 1191
G IPPPPPLP PPPPPLPG AGI PPPPPLPG AG+P PPPPPLP
Sbjct: 672 GTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMP----------PPPPPLP 721
Query: 1192 -GVGIPPPPPLPGA-GIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQV 1249
G GIPPPPP PG GIPPPP PGMG+PP PP G G+P P+LP
Sbjct: 722 GGPGIPPPPPFPGGPGIPPPP--PGMGMPPP-----PPFGFGVPAAPVLP---------- 764
Query: 1250 GSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDS 1309
FGL + K+ +P ++ W+++ D
Sbjct: 765 ----------------------FGL-------TPKKLYKPEVQLRRPNWSKL---VAEDL 792
Query: 1310 STSLIWEKIEEPSIDCHEFEELFSK--------TAVKERKK-----PISDTISKTKAKQV 1356
S W K++E D E ELF+K T + KK ++ K K K+
Sbjct: 793 SQDCFWTKVKE---DRFENNELFAKLTLTFSAQTKTSKAKKDQEGGEEKKSVQKKKVKE- 848
Query: 1357 VKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIE 1416
+K+L +K +Q + I + S + ++I++ ++ ++ +V+ +Q L + + ++L+ +
Sbjct: 849 LKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKML- 907
Query: 1417 KHGRSSKDKENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQK 1476
S+ K+ L + EQF + +P R+ ILF+ FSE + +I+ ++ +
Sbjct: 908 -----SELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTA 962
Query: 1477 LCETLKNGPGVMQVLGLVLAFGNYMNGGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLS 1536
CE L+ +L + L GNYMN G++ G A GF + L KL+D KS+D +LL
Sbjct: 963 ACEELRKSESFSNLLEITLLVGNYMNAGSRNAG-AFGFNISFLCKLRDTKSTDQKMTLL- 1020
Query: 1537 YIVSYYLRNFDEDAGKEQCLFPLPEPQDLFQASQMKFEDFQKDLRKLKKDLKACEVEAGK 1596
++L E+ + FP E + +AS++ E+ QK+L ++KK + +VE
Sbjct: 1021 ----HFLAELCENDYPDVLKFP-DELAHVEKASRVSAENLQKNLDQMKKQIS--DVERDV 1073
Query: 1597 VYQVSSKEHMQPFKENMEQFIIQAKIDQEAEENSLTETHKCFLETTAYFFMKPKLGEKEV 1656
++ + F E M F+ A+ + + E YF P K++
Sbjct: 1074 QNFPAATDEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDP----KKL 1129
Query: 1657 SPNAFFSIWHEFSSDFKDFWKKENKLLLQERVKEAEEVCRQKK 1699
S FF H F + F K+ K +E EE R+ K
Sbjct: 1130 SVEEFFMDLHNFRNMFLQAVKENQKR------RETEEKMRRAK 1166
Score = 224 bits (572), Expect = 4e-58
Identities = 133/211 (63%), Positives = 141/211 (66%), Gaps = 22/211 (10%)
Query: 959 LPGAGIPLPPPLPG-AGIPPPPPLPGAG--IPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1015
L A I +PP +P A +PP PPLPG I PPPP PG PPPP P PPPPPLP
Sbjct: 565 LSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP--PPPPPLP 622
Query: 1016 GAG-IPPPPPLPGA-GIPPPPPLPG-AGIPPPPPLP-GAGIPPPPPLP-GAGIPPPPPLP 1070
G I PP LPG I PPPPL G A IPPPPPLP G GIP P LP G IPPPPPLP
Sbjct: 623 GGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLP 682
Query: 1071 GAG--IPPPPPLPG-AGI-PPPPPLPG-AGI-PPPPPLP-GVGIPPPPPLPGA-GIPPPP 1122
G+ PPPPPLPG AGI PPPPPLPG AG+ PPPPPLP G GIPPPPP PG GIPPPP
Sbjct: 683 GSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPP 742
Query: 1123 PLPGAGIPPPPPLPGAGIPPPPPLPRVGIPP 1153
PG G+PPPPP G G+P P LP G+ P
Sbjct: 743 --PGMGMPPPPPF-GFGVPAAPVLP-FGLTP 769
Score = 223 bits (567), Expect = 2e-57
Identities = 138/235 (58%), Positives = 145/235 (61%), Gaps = 34/235 (14%)
Query: 937 LPGAGIPPPPPLPGAA-IPPPPPLPGAG---IPLPPPLPGAGIPPPPPLPGAGIPPPPPL 992
L A I PP +P A +PP PPLPG IP PPP PG PPPP PPPP
Sbjct: 565 LSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIP-PPPAPGDSTTPPPP-------PPPP- 615
Query: 993 PGAGIPPPPPLPGAG-IPPPPPLPGA-GIPPPPPLPG-AGIPPPPPLP-GAGIPPPPPLP 1048
PPPPPLPG I PP LPG I PPPPL G A IPPPPPLP G GIP P LP
Sbjct: 616 -----PPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLP 670
Query: 1049 GA-GIPPPPPLPGAGI--PPPPPLPG-AGIPPPPP-LPG-AGIPPPPP-LPGA-GIPPPP 1100
G IPPPPPLPG+ PPPPPLPG AGIPPPPP LPG AG+PPPPP LPG GIPPPP
Sbjct: 671 GGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPP 730
Query: 1101 PLPG-VGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPP 1154
P PG GIPPPPP G G+PPPPP G G+P P LP P P V + P
Sbjct: 731 PFPGGPGIPPPPP--GMGMPPPPPF-GFGVPAAPVLPFGLTPKKLYKPEVQLRRP 782
Score = 218 bits (555), Expect = 4e-56
Identities = 130/213 (61%), Positives = 138/213 (64%), Gaps = 31/213 (14%)
Query: 912 PPPLPG-AGIPPPPPLPGAG--ILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP 968
PP +P A +PP PPLPG I+P PP PG PPPP P PPPPPLPG
Sbjct: 573 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP--PPPPPLPG------- 623
Query: 969 PLPGAGIPPPPPLPGA-GIPPPPPLPG-AGIPPPPPLP-GAGIPPPPPLP-GAGIPPPPP 1024
G I PP LPG I PPPPL G A IPPPPPLP G GIP P LP G IPPPPP
Sbjct: 624 ---GVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPP 680
Query: 1025 LPGAG--IPPPPPLPG-AGI-PPPPPLPG-AGI-PPPPPLPGA-GIPPPPPLPGA-GIPP 1076
LPG+ PPPPPLPG AGI PPPPPLPG AG+ PPPPPLPG GIPPPPP PG GIPP
Sbjct: 681 LPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPP 740
Query: 1077 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP 1109
PP PG G+PPPPP G G+P P LP G+ P
Sbjct: 741 PP--PGMGMPPPPPF-GFGVPAAPVLP-FGLTP 769
Score = 212 bits (539), Expect = 3e-54
Identities = 127/207 (61%), Positives = 135/207 (65%), Gaps = 21/207 (10%)
Query: 890 TLPSTAIPQPPPLQGTEMLPPPPPPLPGAG--IPPPPPLPGAGILPLPPLPGAGIPPPPP 947
+L + AI PP + +PP PP LPG I PPPP PG P PP P PPPPP
Sbjct: 564 SLSAAAITVPPSVPSRAPVPPAPP-LPGDSGTIIPPPPAPGDSTTPPPPPPPP--PPPPP 620
Query: 948 LPGAA-IPPPPPLPGA-GIPLPPPLPG-AGIPPPPPLP-GAGIPPPPPLP-GAGIPPPPP 1002
LPG I PP LPG I PPPL G A IPPPPPLP G GIP P LP G IPPPPP
Sbjct: 621 LPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPP 680
Query: 1003 LPGAG--IPPPPPLPG-AGI-PPPPPLPG-AGI-PPPPPLPGA-GIPPPPPLPGA-GIPP 1054
LPG+ PPPPPLPG AGI PPPPPLPG AG+ PPPPPLPG GIPPPPP PG GIPP
Sbjct: 681 LPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPP 740
Query: 1055 PPPLPGAGIPPPPPLPGAGIPPPPPLP 1081
PP PG G+PPPPP G G+P P LP
Sbjct: 741 PP--PGMGMPPPPPF-GFGVPAAPVLP 764
Score = 184 bits (467), Expect = 6e-46
Identities = 108/196 (55%), Positives = 115/196 (58%), Gaps = 26/196 (13%)
Query: 855 IPSPPPLPCTESS----SSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPP 910
+P PPLP + PG PPPPPP P P I PP L G + P
Sbjct: 582 VPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISP 641
Query: 911 PPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLP-GAAIPPPPPLPGAG--IPLP 967
PPP A IPPPPPLP G GIP P LP G AIPPPPPLPG+ P P
Sbjct: 642 PPPLSGDATIPPPPPLP----------EGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 691
Query: 968 PPLPG-AGI-PPPPPLPG-AGI-PPPPPLPGA-GIPPPPPLPGA-GIPPPPPLPGAGIPP 1021
PPLPG AGI PPPPPLPG AG+ PPPPPLPG GIPPPPP PG GIPPPP PG G+PP
Sbjct: 692 PPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPP--PGMGMPP 749
Query: 1022 PPPLPGAGIPPPPPLP 1037
PPP G G+P P LP
Sbjct: 750 PPPF-GFGVPAAPVLP 764
Score = 128 bits (321), Expect = 5e-29
Identities = 119/363 (32%), Positives = 158/363 (43%), Gaps = 71/363 (19%)
Query: 632 PDEEHRLEDAETES--QSAVSETPQKRSDAVQKEVVDMKSEGQATVIQQLEQTIE----D 685
PD + R E E + +T ++S+A E+ + K + + T +L+ ++ D
Sbjct: 450 PDFKCRHLQIEIEGLIDQMIDKTKVEKSEAKAAEL-EKKLDSELTARHELQVEMKKMESD 508
Query: 686 LRTKIAELERQYPALDTE---VASGHQGLENGVTA-SGDVCLEALRLEEKEVRHHRILEA 741
K+ +L+ + AL +E +A+ Q LE V+ +G+V LE+ + E
Sbjct: 509 FEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKK------EM 562
Query: 742 KSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSH 801
S+ + +T+PP +P R P PP + I+ P DS
Sbjct: 563 ASLSAA------AITVPP--SVPSRAPVPPAPP------LPGDSGTIIPPP--PAPGDST 606
Query: 802 QPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPL 861
P PPPPP L P S P + S IP PPPL
Sbjct: 607 TPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAI---------SPPPPLSGDATIPPPPPL 657
Query: 862 P---CTESSSSMPGLGMVPPPPPPLPGMT-----VPTLPSTA--IPQPPPLQGTEMLPPP 911
P S SS+PG G PPPPPLPG P LP +A P PPPL G +PPP
Sbjct: 658 PEGVGIPSPSSLPG-GTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPP 716
Query: 912 PPPLP---GAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP 968
PPP G GIPPPPP PG G GIPPPP PG +PPPPP G G+P P
Sbjct: 717 PPP--LPGGPGIPPPPPFPG----------GPGIPPPP--PGMGMPPPPPF-GFGVPAAP 761
Query: 969 PLP 971
LP
Sbjct: 762 VLP 764
Score = 46.6 bits (109), Expect = 2e-04
Identities = 70/316 (22%), Positives = 101/316 (31%), Gaps = 70/316 (22%)
Query: 629 SKPPDEEHRLEDAETESQSAVSETPQKRSDAVQKEVVDMKSEGQATVIQQLEQTIEDLRT 688
+K + E +L+ T E + SD QK + D++ E A L + + T
Sbjct: 479 AKAAELEKKLDSELTARHELQVEMKKMESDFEQK-LQDLQGEKDA-----LHSEKQQIAT 532
Query: 689 KIAELERQYPALDTEVASGHQGLENGVTASGDVCLEALRLEEKEVRHHRILEAKSIQTSP 748
+ +LE + L EVA + LE+ + A+ + + A + P
Sbjct: 533 EKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPL---P 589
Query: 749 TEEGGVLTLPPVDGLPGRPPCPP-----------------------GAESGPQTKFCSEI 785
+ G ++ PP G PP PP G P +
Sbjct: 590 GDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDA 649
Query: 786 SLIVSP---RRISVQLDSHQP-----------TQSISQPPPPPSLLWSAG--------QG 823
++ P + + S P S PPPPP L SAG G
Sbjct: 650 TIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPG 709
Query: 824 QPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTES-SSSMPGLGMVPPPPPP 882
+ G PP IP PPP P PG+GM PPPP
Sbjct: 710 EAGMPPP---------------PPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFG 754
Query: 883 LPGMTVPTLPSTAIPQ 898
P LP P+
Sbjct: 755 FGVPAAPVLPFGLTPK 770
Score = 44.3 bits (103), Expect = 0.001
Identities = 54/217 (24%), Positives = 73/217 (33%), Gaps = 30/217 (13%)
Query: 189 ATEQEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVS--PQPGAF 246
ATE++DL +++ Q + +L +L+ +++ A PP+ S P P A
Sbjct: 531 ATEKQDLEAEVSQLTG----EVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPA- 585
Query: 247 LGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPS 306
L G SG P +P D P P PP PGG+ +S PS
Sbjct: 586 ----PPLPGDSGTIIPPPPAP---------GDSTTPPPPPPPPPPPPPLPGGVCISSPPS 632
Query: 307 LPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEW 366
LP + P S P P E G P + P PG
Sbjct: 633 LPGGTAISPPPPLSGDATIPPPPPLPEGVGIP------SPSSLPGGTAIPPPPPLPGSAR 686
Query: 367 APEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAP 403
P P G P P P A +P P P
Sbjct: 687 IPPPPPPLPGSAGIPPPP----PPLPGEAGMPPPPPP 719
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 196 bits (497), Expect = 2e-49
Identities = 274/984 (27%), Positives = 357/984 (36%), Gaps = 156/984 (15%)
Query: 398 PGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPS-QSPNQSPRIKRRPEPSLSRGSR 456
P SPA + K P + P ++P +SPS QS + SP I PE +L++ S
Sbjct: 543 PFSPAQAGLTTKKDPTVLPLV-------QAAPKNSPSFQSTSSSPEIPLSPEATLAKKSL 595
Query: 457 TALASVAAPAKKHRADGGLAAGLSRSADWTEELGARTPRVGGSAHLLERGVASDSGGGVS 516
+ PA + G++ SA + P G LL+ + + +
Sbjct: 596 GEPLPIGKPASSMTSP----LGVNSSASVIKTDSYAGPDSAGP--LLKSSLITPTVAAFP 649
Query: 517 PALAAKASGAPAAADGFQN-VFTGRTLLEKLFS-QQENGPPEEAEKFCSRIIAMGLLLPF 574
A A AP A G T LE S +N P +E ++
Sbjct: 650 LESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTAS---- 705
Query: 575 SDCFREPCNQNAQTNAASFDQDQLYTWAAVSQPTHSLDYSEGQFPRRVPSMG-PPSKPPD 633
+C P QN A+ V P + P+ VPS PP+ P
Sbjct: 706 ENCPVAPSPQNTCAPLATL----------VLAP---------EIPKSVPSPSLPPAGTPP 746
Query: 634 EEHRLED-AETESQSAVSETPQKRSDAVQKEVVDMKSEGQATVIQQLEQTIEDLRTKIAE 692
+++ + T + + V+ +P++ S+G T L + L ++
Sbjct: 747 GTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTY---LADSPSPLGVSVSP 803
Query: 693 LERQYPALDTEVASGHQGLENGVTASGDVCLEALRLEEKEVRHHRILEAKSIQTSPTEEG 752
++ P T+ S G +S +EA L E + ++ + SPT
Sbjct: 804 QTKRPP---TKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT--- 857
Query: 753 GVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPP 812
PP P GA + S + + P+ PT S+ P
Sbjct: 858 --------------PPSPKGAPTPSAVTPLSPKGVTLPPKET--------PTPSVVNLPF 895
Query: 813 PPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPG 872
P G P + ++S SS+ K + P+P +P + S P
Sbjct: 896 PKE-----GPATPAPKQAPALSM---------TSSSPKKARATPAPKGIPASPSPKGAP- 940
Query: 873 LGMVPP---PPPPLPGMTVPT---LPSTAIPQPPPLQGTEMLPPPP-PPLPGAGIPPPPP 925
PP PP P G P+ P+ PP +G P P P P A PP P
Sbjct: 941 ---TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK 997
Query: 926 LPGAGILPLP---PLPGAGIPPPP-------PLPGAAIPPP---PPLPGAGIPLPPPLP- 971
G P P P P A PP P P P A PP PP P G P PLP
Sbjct: 998 --GGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP-KGSPAATPLPK 1054
Query: 972 GAGIPPPPPLPG-AGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPP--PPPLP 1026
GA P LP G P P L GA PP PP P G P P GA +PP PP P
Sbjct: 1055 GAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGG-PATPSPKGAPMPPAATPPSP 1113
Query: 1027 GAGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPG 1082
G+ PP GA P PP P G+ PPP GA P PP P G+ PPP G
Sbjct: 1114 KGGLATPPH-KGAPTTPAATPPSPKGGLATPPP-KGAPTTPAATPPSPKGGLATPPP-KG 1170
Query: 1083 AGIPP--PPPLPGAGIPPPPPLPGVGIP---PPPPLPGAGIPPP---PPLPGAGIPPPPP 1134
A P PP P G+ P P P PP P G P P P P A PP P
Sbjct: 1171 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA--TPPSP 1228
Query: 1135 LPGAGIPPPPPLPRV-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP----P 1189
G P P P PP P G PPP P PP L G G+ PP P
Sbjct: 1229 KGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG-GLATPPHKGAP 1287
Query: 1190 LPGVGIPPPPPLPGAGIPPP--PPLPGMGIPPAP--APPLPPPGTGIPPPPLLPVS--GP 1243
P V + PP P G PP P P PP+P +P PPP PP + P S G
Sbjct: 1288 NPAV-VTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGT 1346
Query: 1244 PLLPQV-----GSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYW 1298
P LP G T P+ + P PS G M ++ P P P
Sbjct: 1347 PTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT-PPSPKRGPAIPSPKGDPTSP 1405
Query: 1299 TRIQLHSKRDSSTSLIWEKIEEPS 1322
I L K+ +T + E PS
Sbjct: 1406 AVIPLSPKKAPATPVTREGAATPS 1429
Score = 171 bits (433), Expect = 6e-42
Identities = 178/575 (30%), Positives = 205/575 (35%), Gaps = 114/575 (19%)
Query: 746 TSPTEEGGVLTLPPVDGLPGRPPC-PPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPT 804
T P+ +GG T P G P P PP + GP T SP+
Sbjct: 969 TPPSPKGGPAT-PSPKGAPTPPAATPPSPKGGPATP---------SPK------------ 1006
Query: 805 QSISQPPPPPSLLWSAGQGQPGSQP-PHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPC 863
P PP++ + +G P + P P ST PP
Sbjct: 1007 ----GAPTPPAVTPPSPKGSPAATPFPKGAST-----------------------PPAAT 1039
Query: 864 TESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPP 923
S P +P P P T+P+ P P L+G P PP P G P
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPS--PKGGPATPSLKGAPTPPAATPPSPKGG-PAT 1096
Query: 924 PPLPGAGILP--LPPLPGAGIPPPPPLPGAAIP-PPPPLPGAGIPLPPPLPGAGIPP--P 978
P GA + P PP P G+ PP P PP P G+ PPP GA P
Sbjct: 1097 PSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPP-KGAPTTPAAT 1155
Query: 979 PPLPGAGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPP--PPPLPGAGIPPPP 1034
PP P G+ PPP GA P PP P G+ P P GA P PP P G+ P
Sbjct: 1156 PPSPKGGLATPPP-KGAPTTPAATPPSPKGGLATPSP-KGAPTTPAATPPSPKGGLATPS 1213
Query: 1035 PLPGAGIPP--PPPLPGAGIPPPPPLPGAGIP---PPPPLPGAGIPPPPPLPGAGIPPPP 1089
P GA P PP P G+ P P P PP P G PPP P PP
Sbjct: 1214 P-KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPP 1272
Query: 1090 PLPGAGIPPP---PPLPGVGIPPPP-------PLPGAGIPP--PPPLPGAGIPPPPPLPG 1137
L G PP P P V PP P P GA PP PP P G P PP G
Sbjct: 1273 SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSP-KGSPGTPPPKG 1331
Query: 1138 AGIPP--PPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP----GVGIPPPPPLP 1191
A PP PP P+ P P + P P G PP P G + PP P
Sbjct: 1332 APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKR 1391
Query: 1192 GVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIP------PPPLLPVS---- 1241
G IP P G P P + + APA P+ G P PP + PVS
Sbjct: 1392 GPAIPSP-----KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKA 1446
Query: 1242 --------GPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
GP G TLP PP P
Sbjct: 1447 PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAP 1481
Score = 137 bits (344), Expect = 1e-31
Identities = 193/680 (28%), Positives = 231/680 (33%), Gaps = 142/680 (20%)
Query: 746 TSPTEEGGVLTLPPVDGLP----GRPPCPPGAESGPQTKFCSEISLIVSPRR---ISVQL 798
T P+ +GG T P + G P PP P G + P K P ++
Sbjct: 1063 TLPSPKGGPAT-PSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121
Query: 799 DSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSP 858
PT + PP P +G + PP T + + K P P
Sbjct: 1122 HKGAPTTPAATPPSP--------KGGLATPPPKGAPTT-----PAATPPSPKGGLATPPP 1168
Query: 859 PPLPCTESSSS-MPGLGMVPPPP---PPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPP 914
P T +++ P G+ P P P P T P+ P + P P +G P PP
Sbjct: 1169 KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS-PKGGLATPSP-KGAPTTPAATPP 1226
Query: 915 LPGAGIPPPPPLPGAGILPL--PPLPGAGIPPPPPLPGAAIPP---PPPLPGAGIPLPP- 968
P G+ P P GA P PP P G PPP GA PP PP L G G+ PP
Sbjct: 1227 SPKGGLATPSP-KGAPTTPAATPPSPKGGPATPPP-KGAPTPPAATPPSLKG-GLATPPH 1283
Query: 969 ---PLPGAGIPPPPPLPGAGIPPP--PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-- 1021
P P A + PP P G PP P P A PP P G P PP GA PP
Sbjct: 1284 KGAPNP-AVVTPPSPKGGPATSPPKGAPTPPAATPPSP----KGSPGTPPPKGAPTPPAV 1338
Query: 1022 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP----GAGIPPPPPLPGAGIPPP 1077
PP P P P + P P G PP P G + PP P G IP P
Sbjct: 1339 TPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP 1398
Query: 1078 --PPLPGAGIP------PPPPL-------PGAGIPPPPPLPGVGIPPPP----PLPGAGI 1118
P A IP P P+ P G PP + V + P P G
Sbjct: 1399 KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPAT 1458
Query: 1119 PP---PPPLPGAGIPPP--PPLP-----------GAGIPPP---PPLPRVGIPPPPPLPG 1159
P P LP P P PP P P P P LP V P +P
Sbjct: 1459 PSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPA 1518
Query: 1160 ----------------------------AGIPP----PPPLPGAGIPPPPPLPGV----- 1182
A IPP P P IP P P
Sbjct: 1519 TPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKE 1578
Query: 1183 GIPPPPPLPGV--GIPPPPPL---PGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPL 1237
PP P G P P L P P P P PPA PP P G P P
Sbjct: 1579 ASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAP---TPPAVTPPSPEKGPATPAPKG 1635
Query: 1238 LPVSGPPLLPQ--VGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQP-IEPCRPMK 1294
P S PP+ P S T P C + +P GL + + K+ + P
Sbjct: 1636 TPTS-PPVTPSSLKDSPTSPASVTCK-MGATVPQASKGLPAKKGPTALKEVLVAPAPEST 1693
Query: 1295 PLYW--TRIQLHSKRDSSTS 1312
P+ TR +K+ S+TS
Sbjct: 1694 PIITAPTRKGPQTKKSSATS 1713
Score = 103 bits (258), Expect = 1e-21
Identities = 151/622 (24%), Positives = 202/622 (32%), Gaps = 91/622 (14%)
Query: 736 HRILEAKSIQTSPTEEGGVLTLPPVDGLP----GRPPCPPGAESGPQTKFCSEISLIVSP 791
H+ ++ T P+ +GG T PP G P PP P G+ P K + P
Sbjct: 1283 HKGAPNPAVVTPPSPKGGPATSPP-KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP 1341
Query: 792 RR-------ISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHS 844
+ PT S+ P P + +G P PP S +
Sbjct: 1342 SPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGD 1401
Query: 845 VSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQ----PP 900
+S + P P T ++ P G + PP + +++ P+T+ P+ P
Sbjct: 1402 PTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPA--VTPVSLKKAPATSAPKGGPATP 1459
Query: 901 PLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPP---PPLPGAAIPPPP 957
+G LP PP P PP P P P P P LP A IP P
Sbjct: 1460 SSKGDPTLPAVTPPSP-----KEPPAPKQVATSSSPKKAPATPAPMGAPTLP-AVIPSSP 1513
Query: 958 PLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1017
+P P I P L P A IPP +P P P P
Sbjct: 1514 K----EVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE 1569
Query: 1018 GIPPPPPLPGAGIPPPPPLPGAGIPPP-----PPLPGAGIPPPPPLPGAGIPPPP----- 1067
P + P P G P P PP + P P P A PP P
Sbjct: 1570 APATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPA 1629
Query: 1068 -PLPGAGIPPPPPLPGAGIPPPPPLPGA---GIPPPPPLPGVGIPP---PPPLPGAGIPP 1120
P P G P PP+ + + P P + + P G+P P L + P
Sbjct: 1630 TPAP-KGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP 1688
Query: 1121 PP---PLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLP-------- 1169
P P+ A P + PP P P + + P P LP
Sbjct: 1689 APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKT 1748
Query: 1170 ----GAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIP--PAPAP 1223
A P PL PL P P + P P + +P P+P P
Sbjct: 1749 AKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVP 1808
Query: 1224 PLPP--------PGTGI--PPPPLLPVSGPPLLPQVGSS-------------TLPTPQVC 1260
LPP PG + P PL P LLP + +PTP+
Sbjct: 1809 TLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSA 1868
Query: 1261 GFLPPPLPSGLFGLGMNQDKGS 1282
G +P P PS + N +KGS
Sbjct: 1869 G-IPVPTPSAKQPVTKN-NKGS 1888
Score = 86.7 bits (213), Expect = 2e-16
Identities = 182/724 (25%), Positives = 220/724 (30%), Gaps = 245/724 (33%)
Query: 768 PCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGS 827
PC A P T F E++ VSP S + + +PT + P +
Sbjct: 446 PCTIAA--APTTTF--EVATCVSPPMSSGPISNIEPTSPAALVMAPVA------------ 489
Query: 828 QPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPP-------- 879
P ST+ T+ IP PPLP E ++P +V P
Sbjct: 490 --PKEPSTQVATT------------LRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTV 535
Query: 880 PPPLPGM---------------TVPTLPSTAIPQPPPLQGTEMLPPPP------------ 912
P L G TV L A P Q T P P
Sbjct: 536 PASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSL 595
Query: 913 -PPLP-------------------------GAGIPPPPPL-------PGAGILPLPPLPG 939
PLP AG PL P PL
Sbjct: 596 GEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADP 655
Query: 940 AGIPP-------------PPPLPG--AAIPPPPPLPGAGIPLPPPLPGAG----IPPPPP 980
AG+ P P L G + P P+ + P +P A + P P
Sbjct: 656 AGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQ 715
Query: 981 ---LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP-----------LPGAGIPPPPPLP 1026
P A + P +P + P P LP AG PP P A P P
Sbjct: 716 NTCAPLATLVLAPEIPKS--VPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTE 773
Query: 1027 GAG--------------IPPPPPLPGAGIPP----PPPLPGAGIPPPP---------PLP 1059
+G P PL G + P PP G+ P P P+
Sbjct: 774 DSGASATASSKGTLTYLADSPSPL-GVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVE 832
Query: 1060 GAGIP------------------PPPPLPGAGIPPP---PPLPGAGIPPPP--------- 1089
+ +P P PP P G P P PL G+ PP
Sbjct: 833 ASFLPENSLSFQGSKDSPATTHSPTPPSP-KGAPTPSAVTPLSPKGVTLPPKETPTPSVV 891
Query: 1090 ----PLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP- 1144
P G P P P + + P P P +P + P P P A PP P
Sbjct: 892 NLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPK 951
Query: 1145 -----------PLPRVGIPPPP------------PLPGAGIPPPP------PLP-GAGIP 1174
P P PP P P P A PP P P P GA P
Sbjct: 952 GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTP 1011
Query: 1175 P--PPPLPGVGIPPPPPLP-GVGIPP--PPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPG 1229
P PP P G P P P G PP PP P G P PLP G P PA LP P
Sbjct: 1012 PAVTPPSP-KGSPAATPFPKGASTPPAATPPSP-KGSPAATPLP-KGAPTTPAATLPSPK 1068
Query: 1230 TGIPPPPL----LPVSGPPLLPQVGSSTLPTPQVCGFLP---PPLPSGLFGLGMNQDKGS 1282
G P L P + P P+ G +T P+P+ P PP P G GL KG+
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPKGGPAT-PSPKGAPMPPAATPPSPKG--GLATPPHKGA 1125
Query: 1283 RKQP 1286
P
Sbjct: 1126 PTTP 1129
Score = 68.2 bits (165), Expect = 7e-11
Identities = 175/804 (21%), Positives = 262/804 (32%), Gaps = 128/804 (15%)
Query: 236 PTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQ---Q 292
P A P P L P+ A P SP A + P + AA P P+
Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATPP-SPKGGLATPSPKGAPTTPAATPPSPKGGLA 1210
Query: 293 PPSPGGLPVSEAPSLPA-----AQPAAKDSPSSTAF--PFPEAGPGEEAAGAPVRGAGDT 345
PSP G P + A + P+ A P+ K +P++ A P P+ GP A P +GA T
Sbjct: 1211 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGP----ATPPPKGA-PT 1265
Query: 346 DEEGEEDAFEDAPRGSPGEEWAPEVG-EDAPQRLGEEPEEEAQGPDAPAAASLP---GSP 401
+ + +P + AP P G +G P AA+ P GSP
Sbjct: 1266 PPAATPPSLKGG-LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSP 1324
Query: 402 -APSQRCFKPYPLITPCYIK-TTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTAL 459
P + P +TP K T T ++P+ S+ +P K P P + S
Sbjct: 1325 GTPPPKGAPTPPAVTPPSPKGTPTLPATTPS---SKGGPTTPSSKEGPTPPAATPSHKGG 1381
Query: 460 ASVAAPAKKHRADGGLAAGLSRSADWTEELGARTPRVGGSAHLLERGVASDSGGGVSPAL 519
++ P+ K G A + + + +P+ + + G A+ S G ++P
Sbjct: 1382 PAMTPPSPKR----GPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPA 1437
Query: 520 AAKASGAPAAADGFQNVFTGRTLLEKLFSQQENGPPEEAEKFCSRIIAMGLLLPFSDCFR 579
S A A S + GP + K + A+
Sbjct: 1438 VTPVSLKKAPAT----------------SAPKGGPATPSSKGDPTLPAV----------- 1470
Query: 580 EPCNQNAQTNAASFDQDQLYTWAAVSQPTHSLDYSEGQFPRRVPSMGPPSKPPDEEHRLE 639
T + +P + P++ P+ P P L
Sbjct: 1471 --------------------TPPSPKEPPAPKQVATSSSPKKAPATPAPMGAP----TLP 1506
Query: 640 DAETESQSAVSETPQKRSDAVQKEVVDMKSEGQATVIQQLEQTIEDLRTKIAELERQYPA 699
S V TP R D + + + AT+ + E I T ++ PA
Sbjct: 1507 AVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPK-EALIPPAMT--VPSPKKTPA 1563
Query: 700 LDTEVASGHQGLENGVTASGDVCLEALR--LEEKEVRHHRILEAKSIQTSPTEEGGVLTL 757
+ T + ++ V + KE+ + + S + +PT
Sbjct: 1564 IPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPA---VT 1620
Query: 758 PPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQP------- 810
PP P P G + P S SP ++ ++ + P S P
Sbjct: 1621 PPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTA 1680
Query: 811 -------PPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPC 863
P P S + G Q S +T + S + K + +P PL
Sbjct: 1681 LKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLP 1740
Query: 864 TESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPP 923
+ SS G P G P P + P E + P P + P P
Sbjct: 1741 VQKDSSKTAKGKDASHSP--KGPLAP--PESKASTPLTAAAFEKVLPKPESASVSAAPSP 1796
Query: 924 PPLPGAGILPLPPLPGAGIPPP----PPLPGAAI-PPPPPLPGAG----IPLPPPLPGAG 974
P LPL P P +PP P PG + P PL A +PL PP P +G
Sbjct: 1797 PV-----SLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISG 1851
Query: 975 IPP-------PPPLPGAGIPPPPP 991
P P AGIP P P
Sbjct: 1852 GVPFQSVLVNMPTPKSAGIPVPTP 1875
Score = 49.3 bits (116), Expect = 3e-05
Identities = 53/190 (27%), Positives = 75/190 (39%), Gaps = 34/190 (17%)
Query: 262 EAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSE----APSLPAAQPAAKDS 317
E P +P +QA ALS ++ P++ + P+P G+P S AP+ PAA P +
Sbjct: 898 EGPATPAPKQA-PALS----MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG 952
Query: 318 PSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQR 377
+T P P+ P AA P +P+G P A + AP
Sbjct: 953 GPAT--PSPKWAPTPPAATPP------------------SPKGGP----ATPSPKGAPTP 988
Query: 378 LGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSP 437
P GP P+ P PA + K P TP +T ++P SP SP
Sbjct: 989 PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP-PSPKGSP 1047
Query: 438 NQSPRIKRRP 447
+P K P
Sbjct: 1048 AATPLPKGAP 1057
Score = 43.9 bits (102), Expect = 0.001
Identities = 72/279 (25%), Positives = 92/279 (32%), Gaps = 35/279 (12%)
Query: 262 EAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEA-----PSLPAAQPAAKD 316
EA P+ + D P A P PPSP G P A P P
Sbjct: 832 EASFLPENSLSFQGSKDSP----ATTHSPT-PPSPKGAPTPSAVTPLSPKGVTLPPKETP 886
Query: 317 SPSSTAFPFPEAGPGEEA-AGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAP 375
+PS PFP+ GP A AP T ++ AP+G P A + AP
Sbjct: 887 TPSVVNLPFPKEGPATPAPKQAPALSM--TSSSPKKARATPAPKGIP----ASPSPKGAP 940
Query: 376 QRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQ 435
P GP P+ P PA + K P TP SP +P+
Sbjct: 941 TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGP-ATP-----------SPKGAPTP 988
Query: 436 SPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLAAGLSRSADWT----EELGA 491
P K P +G+ T A K A G S T + A
Sbjct: 989 PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA 1048
Query: 492 RTPRVGGSAHLLERGVASDSGGGVSPALAAKASGAPAAA 530
TP G+ + S GG +P+L K + P AA
Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGGPATPSL--KGAPTPPAA 1085
Score = 43.5 bits (101), Expect = 0.002
Identities = 76/313 (24%), Positives = 103/313 (32%), Gaps = 49/313 (15%)
Query: 235 PPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPP 294
PP A P P P+ A P SP A + P A P P+ P
Sbjct: 965 PPAATPPSPKGGPATPSPKGAPTPPAATPP-SPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023
Query: 295 SPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAF 354
+ P + A P+ K SP++T P P+ P AA P
Sbjct: 1024 AATPFPKGASTPPAATPPSPKGSPAAT--PLPKGAPTTPAATLP---------------- 1065
Query: 355 EDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYP-- 412
+P+G P P + + AP P GP P+ P PA + P P
Sbjct: 1066 --SPKGGPA---TPSL-KGAPTPPAATPPSPKGGPATPSPKGAPMPPAAT----PPSPKG 1115
Query: 413 -LITPCYIKTTTRQLSSPNHSP-----SQSPNQSPRIKRRPEPSLSRGSRTAL---ASVA 463
L TP + T ++P SP + P +P PS G T A
Sbjct: 1116 GLATPPHKGAPTTPAATP-PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT 1174
Query: 464 APAKKHRADGGLAAGLSRSADWTEELGARTPRVGGSAHLLERGVASDSG-------GGVS 516
A GGLA + A T +P+ GG A +G + GG++
Sbjct: 1175 PAATPPSPKGGLATPSPKGAPTTPAATPPSPK-GGLATPSPKGAPTTPAATPPSPKGGLA 1233
Query: 517 PALAAKASGAPAA 529
A PAA
Sbjct: 1234 TPSPKGAPTTPAA 1246
Score = 41.6 bits (96), Expect = 0.007
Identities = 61/243 (25%), Positives = 87/243 (35%), Gaps = 32/243 (13%)
Query: 230 EEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPRE 289
E PA P + P + LL A AP A++ S P+ A P
Sbjct: 1515 EVPATPSSRRDP-----IAPTATLLSKKTPATLAPKEALIPPAMTVPS--PKKTPAIPTP 1567
Query: 290 PQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEG 349
+ P +P S P++ + SP P P + A P + E+G
Sbjct: 1568 KEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKG 1627
Query: 350 EEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEA-----QGPDAP-AAASLPGSPAP 403
AP+G+P +P V P L + P A G P A+ LP P
Sbjct: 1628 PA---TPAPKGTP---TSPPV---TPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP 1678
Query: 404 S---QRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALA 460
+ + P P TP I TR+ S + SP P+PS GS+ L+
Sbjct: 1679 TALKEVLVAPAPESTP-IITAPTRKGPQTKKSSATSPPIC------PDPSAKNGSKGPLS 1731
Query: 461 SVA 463
+VA
Sbjct: 1732 TVA 1734
Score = 41.2 bits (95), Expect = 0.009
Identities = 58/232 (25%), Positives = 70/232 (30%), Gaps = 27/232 (11%)
Query: 883 LPGMTVPTLPSTAIPQPPPLQGTEMLP------------PPPPPLPGAGIPPPPPLPGAG 930
+PG T+P+T P P T +LP P P LP P P P +
Sbjct: 1 MPGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSA 60
Query: 931 ILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPP 990
P P PL +P P G +PL G P LP PP
Sbjct: 61 ANQASPFPSPSTIASTPL---EVPFPQSSSGTALPL-----GTAPEAPTFLPNLIGPPIS 112
Query: 991 PLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP----PPPLPGAGIPPP 1044
P A P P L G PL + P + PP PP
Sbjct: 113 PAALALASPMIAPTLKGTP-SSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGS 171
Query: 1045 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1096
A I P P P +P P PP + +P P A I
Sbjct: 172 VITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASI 223
Score = 40.8 bits (94), Expect = 0.011
Identities = 74/293 (25%), Positives = 96/293 (32%), Gaps = 62/293 (21%)
Query: 230 EEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPRE 289
+ PA T+ SP+ R P G P SP + A + + P S P
Sbjct: 907 QAPALSMTSSSPKKA------RATPAPKG----IPASPSPKGAPTPPAATPPSPKGGPAT 956
Query: 290 PQQ----------PPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEA-AGAP 338
P PPSP G P + +P PAA P P+ GP + GAP
Sbjct: 957 PSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP-------PSPKGGPATPSPKGAP 1009
Query: 339 VRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEE------AQGPDAP 392
A +P+GSP P+ P P+ +G
Sbjct: 1010 TPPA----------VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTT 1059
Query: 393 AAASLP---GSPA-PSQRCFKPYPLITPCYIKTTTRQLSSPNHSP-SQSPNQSPRIKRRP 447
AA+LP G PA PS + P TP SP P + SP +P
Sbjct: 1060 PAATLPSPKGGPATPSLKGAPTPPAATP----------PSPKGGPATPSPKGAPMPPAAT 1109
Query: 448 EPSLSRGSRTAL---ASVAAPAKKHRADGGLAAGLSRSADWTEELGARTPRVG 497
PS G T A A GGLA + A T +P+ G
Sbjct: 1110 PPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1162
Score = 37.0 bits (84), Expect = 0.17
Identities = 89/373 (23%), Positives = 111/373 (29%), Gaps = 52/373 (13%)
Query: 901 PLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLP 960
P + TE +P LP P A LP + PG +PP P
Sbjct: 2 PGEATETVPATEQELPQ---------PQAETAVLPMSSALSVTAALGQPGPTLPP----P 48
Query: 961 GAGIPLPPPLPGAGIPPPPPLPG--AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1018
+ P PL A P P P A P P P + PL G P LP
Sbjct: 49 CSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPL-GTAPEAPTFLPNLI 107
Query: 1019 IPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1076
PP P A P P L G PL + P + PP +
Sbjct: 108 GPPISPAALALASPMIAPTLKGTP-SSSAPLALVALAPHSVQKSSAFPP-------NLLT 159
Query: 1077 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1136
PP A I P P + P +P P PP + +P P
Sbjct: 160 SPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTP 219
Query: 1137 GAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPP----PPLPGVGIPPPPPLPG 1192
A I + G+ A +P P I P + V I P P
Sbjct: 220 MASI-------QSGV--------ASLPQTTPTTTLAIASPQVKDTTISSVLISPQNP-GS 263
Query: 1193 VGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPP------GTGIPPPPLLPVSGPPLL 1246
+ + P P A LP + A P PP G+ + P LL
Sbjct: 264 LSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLL 323
Query: 1247 PQVGSSTLPTPQV 1259
Q G S L P V
Sbjct: 324 GQTGPSALSDPTV 336
Score = 31.2 bits (69), Expect = 9.1
Identities = 51/192 (26%), Positives = 65/192 (33%), Gaps = 17/192 (8%)
Query: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEM----LPPP 911
P+ PP PC+ + P P P P T+ + P +P P GT + P
Sbjct: 43 PTLPP-PCSPAPQQCPLSAANQASPFPSPS-TIASTP-LEVPFPQSSSGTALPLGTAPEA 99
Query: 912 PPPLPGAGIPP--PPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPP 969
P LP PP P L A + P L G P P A + P PP
Sbjct: 100 PTFLPNLIGPPISPAALALASPMIAPTLKGT---PSSSAPLALVALAPHSVQKSSAFPPN 156
Query: 970 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1029
L + PP + A L A I P P P +P P PP +
Sbjct: 157 L----LTSPPSVAVAESGSVITL-SAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVST 211
Query: 1030 IPPPPPLPGAGI 1041
+P P A I
Sbjct: 212 VPYHCVTPMASI 223
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 191 bits (484), Expect = 7e-48
Identities = 175/585 (29%), Positives = 205/585 (35%), Gaps = 175/585 (29%)
Query: 857 SPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLP 916
SP P T ++S P + PPPPPP P P PPP PPPPPPLP
Sbjct: 610 SPQPKIVTPYTASQPSPPLPPPPPPPPP------------PPPPP-------PPPPPPLP 650
Query: 917 GAGI--------------------------------PPPPPLPGAGILPLPPLPGAGIPP 944
P PP + + P +P G+ P
Sbjct: 651 SQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVP 710
Query: 945 PPPLPGAAIPPPPPLPGAGI------PLPPPLPGAGIPPP--------------PPLPGA 984
PPP PPPPP PG+ + P P LP PPP PP P
Sbjct: 711 PPP-----PPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTP-- 763
Query: 985 GIPPPPPLPGAGIPPPPPLPGAGIPPP--------------PPLPGAGIPP---PPPLPG 1027
PPPPP+P P PP P IP P PP P +PP P P
Sbjct: 764 --PPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPA 821
Query: 1028 AGIPPPPPLPGAGIPPPP-PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1086
+ IPP PP P +PPP P + PPP P + +P + PPPP P
Sbjct: 822 SYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQ 881
Query: 1087 PPPPLPGAGIPPPPPLPGV---GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1143
P P+P P PP P P+P PPPPP PPPPP P PPP
Sbjct: 882 PLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSP-VPAPPP 940
Query: 1144 PPLPRVGIPP-----------PPPLPGAGIPPPPPLPGAGIP-------PPPPLPGV--- 1182
PP P P PG PPP P + I P P P V
Sbjct: 941 PPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSL 1000
Query: 1183 ----------GIPPPPPLPGVGIPPPP---PLPGAGIP----------PPPPLPGMGIPP 1219
G P LP PP P L G +P P L G G
Sbjct: 1001 VSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDS 1060
Query: 1220 APAPPLPPPGTGIPPPP---LLPVSGPPL-LPQVGSSTLPTPQVCGFLPPPLPSGLFGLG 1275
P PP + PPPP LP+ PP+ +P V S +P+V P P
Sbjct: 1061 VVEFPSPPSDSDFPPPPPETELPL--PPIEIPAVFSGN-TSPKVAVVNPQP--------- 1108
Query: 1276 MNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSSTSLIWEKIEE 1320
K S K+ P RP KR+ ST L +I E
Sbjct: 1109 QQWSKMSVKKAPPPTRP-------------KRNDSTRLTQAEISE 1140
Score = 180 bits (456), Expect = 1e-44
Identities = 137/401 (34%), Positives = 155/401 (38%), Gaps = 116/401 (28%)
Query: 953 IPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL-----PGAG 1007
+PP P P P P +PPPPP P PPPPP P PPPPPL P AG
Sbjct: 606 VPPLSPQPKIVTPYTASQPSPPLPPPPPPPP---PPPPPPP----PPPPPLPSQSAPSAG 658
Query: 1008 IPPPPPLPGAGI----------------PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1051
P + + I P PP + + P +P G+ PPPP
Sbjct: 659 SAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPP----- 713
Query: 1052 IPPPPPLPGAGI------PPPPPLPGAGIPPP--------------PPLPGAGIPPPPPL 1091
PPPPP PG+ + P P LP PPP PP P PPPPP+
Sbjct: 714 PPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTP----PPPPPI 769
Query: 1092 PGAGIPPPPPLPGVGIPPP--------------PPLPGAGIPP---PPPLPGAGIPPPPP 1134
P P PP P V IP P PP P +PP P P + IPP PP
Sbjct: 770 PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPP 829
Query: 1135 LPGAGIPPPPPLPR----VGIPPPPPLP---------GAGIPPPPPLPGAGIPPPPPLPG 1181
P + PPP LP+ PPP PL + PPPP P P P+P
Sbjct: 830 TPPVPV-PPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPA 888
Query: 1182 VGIPPPP--------------PLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPP 1227
P P P+P PPPPP PPPPP P PAPP PP
Sbjct: 889 NVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPP------SPVPAPPPPP 942
Query: 1228 PGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
P T P P SG P G T T G PPP P
Sbjct: 943 PPTASPTP---DKSGSP-----GKKTSKTSSPGGKKPPPTP 975
Score = 173 bits (438), Expect = 1e-42
Identities = 162/529 (30%), Positives = 198/529 (37%), Gaps = 103/529 (19%)
Query: 789 VSPR-RISVQLDSHQPTQSIS-----------QPPPPPSLLWSAGQGQPGSQPP----HS 832
+SP+ +I + QP+ + PPPPP L S GS P +S
Sbjct: 609 LSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYS 668
Query: 833 ISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGL-----GMVPPPPPPLPGMT 887
T Q + +HS + FK PP P +S S P + G+VPPPPPP P T
Sbjct: 669 TITRLQNASQHS-GALFK-------PPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPT 720
Query: 888 -------------VPTLPSTAIPQPPPL---------QGTEMLPPPPPPLPGAGIPPPPP 925
P+LP + P PPPL Q PPPPPP+P P PP
Sbjct: 721 PGSAMAQLKPAPCAPSLPQFSAP-PPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPP 779
Query: 926 LPGAGI--------------LPLPPLPGAGIPP---PPPLPGAAIPPPPPLPGAGIPLPP 968
P I PP P +PP P P + IPP PP P +P PP
Sbjct: 780 KPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVP-PP 838
Query: 969 PLPG----AGIPPPPPLP---------GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1015
LP PPP PL + PPPP P P P+P P PP
Sbjct: 839 TLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAV 898
Query: 1016 GA---GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1072
A P P+P PPPPP PPPPP P PPPPP + P PG
Sbjct: 899 KAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGK 958
Query: 1073 GIPPPPPLPGAGIPPPPPLPGAGIP-------PPPPLPGVG--IPPPPPLPGAGIPPPPP 1123
PG PPP P + I P P P V + P +G P
Sbjct: 959 KTSKTSS-PGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKET 1017
Query: 1124 LPGAGIPPPP-PLPGAGIPPPPPLPRVGIPPPPP-LPGAG----IPPPPPLPGAGIPPPP 1177
LP PP P L +G+ P L + + P L G G + P P + PPPP
Sbjct: 1018 LPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPP 1077
Query: 1178 PLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLP 1226
P + + PP +P V P P P M + AP P P
Sbjct: 1078 PETELPL-PPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRP 1125
Score = 125 bits (314), Expect = 4e-28
Identities = 127/451 (28%), Positives = 163/451 (36%), Gaps = 62/451 (13%)
Query: 755 LTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQ---LDSHQPTQSISQ-- 809
+ +PP +P PP PP G S + S L HQ Q I+Q
Sbjct: 701 ILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQ-VQHITQVA 759
Query: 810 ---PPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTES 866
PPPPP + P PP + T + +V+ + PP+P +
Sbjct: 760 PPTPPPPPPI----PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKK 815
Query: 867 SSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLP---------G 917
+ P + PP PP P + VP P P Q + PPP PL
Sbjct: 816 QPAFPASYI--PPSPPTPPVPVP-------PPTLPKQQSFCAKPPPSPLSPVPSVVKQIA 866
Query: 918 AGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPP 977
+ PPPP P PL P+P P PP A+ P + IP+P P PP
Sbjct: 867 SQFPPPPTPPAMESQPLKPVPANVAPQSPP----AVKAKPKWQPSSIPVPSP----DFPP 918
Query: 978 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1037
PPP PPPPP P PPPPP + P PG PG PPP P
Sbjct: 919 PPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSS-PGGKKPPPTPQR 977
Query: 1038 GAGIP-------PPPPLPGAG--IPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGAGIPP 1087
+ I P P P + P +G P LP PP P L +G+
Sbjct: 978 NSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNL 1037
Query: 1088 PPPL-PGAGIPPPPPLPGVG----IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1142
P L G P L G G + P P + PPPPP P PP+ +
Sbjct: 1038 PGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETEL---PLPPIEIPAVFS 1094
Query: 1143 PPPLPRVGIPPPPPLPGAGI----PPPPPLP 1169
P+V + P P + + PPP P
Sbjct: 1095 GNTSPKVAVVNPQPQQWSKMSVKKAPPPTRP 1125
Score = 96.7 bits (239), Expect = 2e-19
Identities = 139/575 (24%), Positives = 164/575 (28%), Gaps = 281/575 (48%)
Query: 810 PPPPPSLLWSAGQGQPGSQPP----HSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTE 865
PPPPP L S GS P +S T Q + +HS + FK PP P +
Sbjct: 642 PPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHS-GALFK-------PPTPPVMQ 693
Query: 866 SSSSMPGL-----GMVPPPPPPLPGMT-------------VPTLPSTAIPQPPPL----- 902
S S P + G+VPPPPPP P T P+LP + P PPPL
Sbjct: 694 SQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAP-PPPLKIHQV 752
Query: 903 ----QGTEMLPPPPPPLPGAGIPPPPPLP-------------------GAGILPLPPLPG 939
Q PPPPPP+P P PP P A P PP+P
Sbjct: 753 QHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPP 812
Query: 940 AG---------IPPPPPLPGAAIPPP------------PPLPGAGIP---------LPPP 969
A IPP PP P +PPP PP P + +P PPP
Sbjct: 813 AKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPP 872
Query: 970 --------------------------------------LPGAGIPPPPPLPGAGIPPPPP 991
+P PPPPP PPPPP
Sbjct: 873 PTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPP 932
Query: 992 LPGAGIPPPPP---------------------LPGAGIPPPPPLPGAGIP-------PPP 1023
P PPPPP PG PPP P + I P P
Sbjct: 933 SPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEP 992
Query: 1024 PLPGAG-------------------IPPP--PPLPG----AGIPPP------------PP 1046
P +PPP PP PG +G+ P P
Sbjct: 993 KRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPV 1052
Query: 1047 LPGAG---------------IPPPPP---LPGAGIPPPPPLPGAGIP------------- 1075
L G G PPPPP LP I P G P
Sbjct: 1053 LSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWS 1112
Query: 1076 -------PPPPLPGAG-------------------IPPPPPLPGAGIP------------ 1097
PPP P +P P P + +
Sbjct: 1113 KMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRT 1172
Query: 1098 --------------------PPPPLPGVGIPPPPP 1112
P + + +PPPPP
Sbjct: 1173 LQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPP 1207
Score = 75.5 bits (184), Expect = 4e-13
Identities = 58/197 (29%), Positives = 68/197 (34%), Gaps = 60/197 (30%)
Query: 1140 IPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGI---- 1195
+PP P P++ P P +PPPPP P PPPPP P PPPPPLP
Sbjct: 606 VPPLSPQPKIVTPYTASQPSPPLPPPPPPPP---PPPPPPP----PPPPPLPSQSAPSAG 658
Query: 1196 ----------------------------PPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPP 1227
P PP + + P +P G+ P P PP PP
Sbjct: 659 SAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPP 718
Query: 1228 PGTGIPPPPLLPVSGPPLLPQVGSSTLP--------TPQVCGFLPPPLPSGLFGLGMNQD 1279
P G L P P LPQ + P QV PPP P
Sbjct: 719 PTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP----------- 767
Query: 1280 KGSRKQPIEPCRPMKPL 1296
P+ P P KPL
Sbjct: 768 --PIPAPLPPQAPPKPL 782
Score = 45.1 bits (105), Expect = 6e-04
Identities = 75/320 (23%), Positives = 106/320 (33%), Gaps = 64/320 (20%)
Query: 748 PTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSI 807
P E V PP +P PP PP S K S + S +
Sbjct: 920 PPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGS-----------PGKKTSKTSSPGG 968
Query: 808 SQPPPPP----SLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLP- 862
+PPP P S+ S+G P + P S + + S K + P+ PP P
Sbjct: 969 KKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPG 1028
Query: 863 -CTESSSSMPGL---GMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGA 918
S ++PG+ G V P L G +G + + P P +
Sbjct: 1029 KLNLSGVNLPGVLQQGCVSAKAPVLSG-----------------RGKDSVVEFPSPPSDS 1071
Query: 919 GIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPL---PPP------ 969
PPPPP LPLPP+ + P A+ P P + + + PPP
Sbjct: 1072 DFPPPPP---ETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRN 1128
Query: 970 ----LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP--------PLPGAGIPPPPPLPG- 1016
L A I P + +P P P + + P L I L
Sbjct: 1129 DSTRLTQAEISEQPTM-ATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSR 1187
Query: 1017 -AGIPPPPPLPGAGIPPPPP 1035
+ P + +PPPPP
Sbjct: 1188 MSRAEPTATMDDMALPPPPP 1207
Score = 40.0 bits (92), Expect = 0.020
Identities = 68/270 (25%), Positives = 91/270 (33%), Gaps = 77/270 (28%)
Query: 745 QTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPT 804
+TS T G PP GAE P+ K S SL+ + + +S P+
Sbjct: 959 KTSKTSSPGGKKPPPTPQRNSSIKSSSGAEH-PEPKRPSVDSLV---SKFTPPAESGSPS 1014
Query: 805 QSISQPP---PPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPL 861
+ PP P P L +G PG +S + S + PSPP
Sbjct: 1015 KETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVE----FPSPP-- 1068
Query: 862 PCTESSSSMPGLGMVPPPPP---PLPGMTVP------TLPSTAIPQPPPLQGTEM----L 908
S S P PPPP PLP + +P T P A+ P P Q ++M
Sbjct: 1069 ----SDSDFP-----PPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKA 1119
Query: 909 PPPPPP-------LPGAGIPPPPPLPGAGILPLPPL---------PG------------- 939
PPP P L A I P + A ++P P PG
Sbjct: 1120 PPPTRPKRNDSTRLTQAEISEQPTM--ATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKS 1177
Query: 940 -----------AGIPPPPPLPGAAIPPPPP 958
+ P + A+PPPPP
Sbjct: 1178 ITRHGSLSSRMSRAEPTATMDDMALPPPPP 1207
Score = 36.6 bits (83), Expect = 0.22
Identities = 47/190 (24%), Positives = 69/190 (36%), Gaps = 34/190 (17%)
Query: 235 PPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSA--LSDLPESLAAEPREPQQ 292
PP+ +SP P + A + P P T A+ + L +P ++A PQ
Sbjct: 851 PPSPLSPVPSVVKQI----------ASQFP-PPPTPPAMESQPLKPVPANVA-----PQS 894
Query: 293 PPSPGGLPVSEAPSLPAAQPAAKDSP--SSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGE 350
PP+ P + S+P P P SS FP P P P A T ++
Sbjct: 895 PPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSG 954
Query: 351 EDAFEDAPRGSPGEEWAPEVGEDAPQRL--------GEEPEEEAQGPDAPAAASLP--GS 400
+ + SPG + P PQR E PE + D+ + P S
Sbjct: 955 SPGKKTSKTSSPGGKKPP----PTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAES 1010
Query: 401 PAPSQRCFKP 410
+PS+ P
Sbjct: 1011 GSPSKETLPP 1020
Score = 31.2 bits (69), Expect = 9.1
Identities = 25/89 (28%), Positives = 32/89 (35%), Gaps = 10/89 (11%)
Query: 232 PAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQ 291
P PP SP P + S G+ P P T Q S++ + EP+ P
Sbjct: 939 PPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKP--PPTPQRNSSIKSSSGAEHPEPKRPS 996
Query: 292 --------QPPSPGGLPVSEAPSLPAAQP 312
PP+ G P E PAA P
Sbjct: 997 VDSLVSKFTPPAESGSPSKETLPPPAAPP 1025
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 191 bits (484), Expect = 7e-48
Identities = 173/586 (29%), Positives = 264/586 (45%), Gaps = 70/586 (11%)
Query: 1138 AGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGI------PPPPPLP 1191
A PPPPP PPP LPG+ PPPP PPPPPLP VG PPPPPLP
Sbjct: 418 ASTPPPPP-------PPPLLPGSSAEPPPP------PPPPPLPSVGAKALPTAPPPPPLP 464
Query: 1192 GVGI------PPPPPLPGAGI---PPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSG 1242
G+G P PPPLPG+ PPPPPLPG+G PP P P LP G G PPPP
Sbjct: 465 GLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPP------ 518
Query: 1243 PPLLPQVGSSTLPTPQVCGFLPPPLPSGL-FGLGMNQDKGSRKQPIEPCRPMKPLYWTRI 1301
PPLLP S P V G + + + + GLG + S ++ P MK L W ++
Sbjct: 519 PPLLPCTCS-----PPVAGGMEEVIVAQVDHGLG-SAWVPSHRRVNPPTLRMKKLNWQKL 572
Query: 1302 QLHSKRDSSTSLIWEKIEEPSIDCHE-----FEELFSKTAVKERKKPISDTISKTKAKQV 1356
+ R+ ++ +W + P + E E LFS A K K+P K +
Sbjct: 573 PSNVAREHNS--MWASLSSPDAEAVEPDFSSIERLFSFPAAKP-KEPTMVAPRARKEPKE 629
Query: 1357 VKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIE 1416
+ L K+S + I + +++ + D + D+E L+ L + + E+E +
Sbjct: 630 ITFLDAKKSLNLNIFLKQFKCSNEEVAAMIRAGDTTKFDVEVLKQLLKLLPEKHEIENLR 689
Query: 1417 KHGRSSKDKENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQK 1476
+ +E AK L + F L IP + R+ C+L + + +R K +L+
Sbjct: 690 -----AFTEERAK-LASADHFYLLLLAIPCYQLRIECMLLCEGAAAVLDMVRPKAQLVLA 743
Query: 1477 LCETLKNGPGVMQVLGLVLAFGNYMNGGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLS 1536
CE+L + L+L GN++N G+ T G ADGF + L KL + KS N +LL
Sbjct: 744 ACESLLTSRQLPIFCQLILRIGNFLNYGSHT-GDADGFKISTLLKLTETKSQQNRVTLLH 802
Query: 1537 YIVSYYLRNFDEDAGKEQCLFPLPEPQDLFQASQMKFEDFQKDLRKLKKDLKACEVEAGK 1596
+++ E+A K L P+DL Q SQ + + + +LK +E +
Sbjct: 803 HVL--------EEAEKSHPDL-LQLPRDLEQPSQAAGINLEIIRSEASSNLKKL-LETER 852
Query: 1597 VYQVSSKEHMQPFKENMEQFIIQAKIDQEAEENSLTETHKCFLETTAYFFMKPKLGEKEV 1656
S E + + E ++ I + E E ++ + + + + L +
Sbjct: 853 KVSASVAEVQEQYTERLQASISAFRALDELFE-AIEQKQRELADYLCEDAQQLSLEDTFS 911
Query: 1657 SPNAFFSIWHEFSSDFKDFWKKENKLLLQERVKE-AEEVCRQKKGK 1701
+ AF ++ + KD +KE + R ++ AEE R+ +G+
Sbjct: 912 TMKAFRDLFLRALKENKD--RKEQAAKAERRKQQLAEEEARRPRGE 955
Score = 126 bits (317), Expect = 2e-28
Identities = 74/144 (51%), Positives = 77/144 (53%), Gaps = 39/144 (27%)
Query: 1006 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1065
A PPPPP PPP LPG+ PPPP PPPPPLP G P P P
Sbjct: 418 ASTPPPPP-------PPPLLPGSSAEPPPP------PPPPPLPSVGAKALPTAP-----P 459
Query: 1066 PPPLPGAGI--PPPPPLPGAGIPPPPPLPGAG---IPPPPPLPGVGIPPPPP--LPGAGI 1118
PPPLPG G PP PPL PPPLPG+ PPPPPLPG+G PPPPP LPG G
Sbjct: 460 PPPLPGLGAMAPPAPPL-------PPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGW 512
Query: 1119 PPPPPLPGAGIPPPPPLPGAGIPP 1142
PPP PPPP LP PP
Sbjct: 513 GPPP-------PPPPLLPCTCSPP 529
Score = 125 bits (313), Expect = 5e-28
Identities = 73/141 (51%), Positives = 74/141 (52%), Gaps = 33/141 (23%)
Query: 1061 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP 1120
A PPPPP PPP LPG+ PPPP PPPPPLP VG P P P
Sbjct: 418 ASTPPPPP-------PPPLLPGSSAEPPPP------PPPPPLPSVGAKALPTAP-----P 459
Query: 1121 PPPLPGAGI--PPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPP--LPGAGIPPP 1176
PPPLPG G PP PPLP PP P PPPPPLPG G PPPPP LPG G PP
Sbjct: 460 PPPLPGLGAMAPPAPPLP----PPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPP 515
Query: 1177 PPLPGVGIPPPPPLPGVGIPP 1197
P PPPP LP PP
Sbjct: 516 P-------PPPPLLPCTCSPP 529
Score = 123 bits (309), Expect = 1e-27
Identities = 75/153 (49%), Positives = 78/153 (50%), Gaps = 38/153 (24%)
Query: 942 IPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1001
+ P L A PPPP P PP LPG+ PPPP PPPPPLP G P
Sbjct: 408 VSQPRALEQQASTPPPPPP------PPLLPGSSAEPPPP------PPPPPLPSVGAKALP 455
Query: 1002 PLPGAGIPPPPPLPGAGI--PPPPPLPGAGIPPPPPLPGAG---IPPPPPLPGAGIPPPP 1056
P PPPPLPG G PP PPL PPPLPG+ PPPPPLPG G PPPP
Sbjct: 456 TAP-----PPPPLPGLGAMAPPAPPL-------PPPLPGSCEFLPPPPPPLPGLGCPPPP 503
Query: 1057 P--LPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1087
P LPG G PPP PPPP LP PP
Sbjct: 504 PPLLPGMGWGPPP-------PPPPLLPCTCSPP 529
Score = 123 bits (308), Expect = 2e-27
Identities = 72/140 (51%), Positives = 76/140 (54%), Gaps = 33/140 (23%)
Query: 984 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1043
A PPPPP PPP LPG+ PPPP PPPPPLP G P P P
Sbjct: 418 ASTPPPPP-------PPPLLPGSSAEPPPP------PPPPPLPSVGAKALPTAP-----P 459
Query: 1044 PPPLPGAGI--PPPPPLPGAGIPPPPPLPGAGI---PPPPPLPGAGIPPPPP--LPGAGI 1096
PPPLPG G PP PPLP PPLPG+ PPPPPLPG G PPPPP LPG G
Sbjct: 460 PPPLPGLGAMAPPAPPLP-------PPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGW 512
Query: 1097 -PPPPPLPGVGIPPPPPLPG 1115
PPPPP P + PP+ G
Sbjct: 513 GPPPPPPPLLPCTCSPPVAG 532
Score = 120 bits (301), Expect = 1e-26
Identities = 72/148 (48%), Positives = 77/148 (52%), Gaps = 37/148 (25%)
Query: 896 IPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAI-- 953
+ QP L+ PPPPPP PP LPG+ P PP PPPPPLP
Sbjct: 408 VSQPRALEQQASTPPPPPP--------PPLLPGSSAEPPPP------PPPPPLPSVGAKA 453
Query: 954 ----PPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAG---IPPPPPLPGAGIPPPPP--LP 1004
PPPPPLPG G + PP P P PPPLPG+ PPPPPLPG G PPPPP LP
Sbjct: 454 LPTAPPPPPLPGLG-AMAPPAP----PLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLP 508
Query: 1005 GAGIPPPPPLPGAGIPPPPPLPGAGIPP 1032
G G PPP PPPP LP PP
Sbjct: 509 GMGWGPPP-------PPPPLLPCTCSPP 529
Score = 119 bits (297), Expect = 3e-26
Identities = 74/157 (47%), Positives = 79/157 (50%), Gaps = 46/157 (29%)
Query: 1041 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG----- 1095
+ P L PPPP P PP LPG+ PPPP PPPPPLP G
Sbjct: 408 VSQPRALEQQASTPPPPPP------PPLLPGSSAEPPPP------PPPPPLPSVGAKALP 455
Query: 1096 -IPPPPPLPGVG--IPPPPPLPGAGIPPPPPLPGA--GIPP-PPPLPGAGIPPPPPLPRV 1149
PPPPPLPG+G PP PPL PPPLPG+ +PP PPPLPG G PPP
Sbjct: 456 TAPPPPPLPGLGAMAPPAPPL-------PPPLPGSCEFLPPPPPPLPGLGCPPP------ 502
Query: 1150 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP 1186
PPP LPG G PPP PPPP LP PP
Sbjct: 503 ---PPPLLPGMGWGPPP-------PPPPLLPCTCSPP 529
Score = 112 bits (279), Expect = 4e-24
Identities = 75/204 (36%), Positives = 94/204 (46%), Gaps = 36/204 (17%)
Query: 809 QPPPPP------SLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLP 862
+P P P S+ + Q Q GS P ++ + + + ++A + +
Sbjct: 347 RPRPSPLVKAHKSVQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESIL 406
Query: 863 CTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGI-- 920
++ PPPPPP P LP ++ PPP PPPPPLP G
Sbjct: 407 KVSQPRALEQQASTPPPPPP-----PPLLPGSSAEPPPP--------PPPPPLPSVGAKA 453
Query: 921 ----PPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAI---PPPPPLPGAGIPLPPP--LP 971
PPPPPLPG G + PP P P PPPLPG+ PPPPPLPG G P PPP LP
Sbjct: 454 LPTAPPPPPLPGLGAMA-PPAP----PLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLP 508
Query: 972 GAGI-PPPPPLPGAGIPPPPPLPG 994
G G PPPPP P PP+ G
Sbjct: 509 GMGWGPPPPPPPLLPCTCSPPVAG 532
Score = 101 bits (251), Expect = 7e-21
Identities = 78/241 (32%), Positives = 98/241 (40%), Gaps = 63/241 (26%)
Query: 733 VRHHRILEAKSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPR 792
V+ H+ ++A ++ S T P + G+ P A C + S
Sbjct: 354 VKAHKSVQA-NLDQSQRGSSPQNTTTPKPSVEGQQPAAAAA--------CEPVDHAQSES 404
Query: 793 RISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNS 852
+ V Q+ + PPPPP L +P PP
Sbjct: 405 ILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPP---------------------- 442
Query: 853 CNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGT-EMLPPP 911
PPPLP + + ++P PPPPPLPG+ P A P PPPL G+ E LPPP
Sbjct: 443 -----PPPLP-SVGAKALP----TAPPPPPLPGLGAMAPP--APPLPPPLPGSCEFLPPP 490
Query: 912 PPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLP 971
PPPLPG G PPPPP P LPG G PPP PPPP LP PP+
Sbjct: 491 PPPLPGLGCPPPPP---------PLLPGMGWGPPP-------PPPPLLP---CTCSPPVA 531
Query: 972 G 972
G
Sbjct: 532 G 532
Score = 33.9 bits (76), Expect = 1.4
Identities = 34/147 (23%), Positives = 53/147 (36%), Gaps = 9/147 (6%)
Query: 192 QEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDR 251
QE L ++ + + + + + L + Q L ++ ++P +P+P
Sbjct: 330 QECTLEEVVERLLSVKGRPRPSPLVKAHKSVQANLDQSQRGSSPQNTTTPKPS------- 382
Query: 252 FLLGPSGGAGEAPGSPDTEQALSALS-DLPESLAAEPREPQQPPSPGGLPVSEAPSLPAA 310
+ G A A D Q+ S L P +L + P PP P LP S A P
Sbjct: 383 -VEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPP 441
Query: 311 QPAAKDSPSSTAFPFPEAGPGEEAAGA 337
P S + A P P GA
Sbjct: 442 PPPPLPSVGAKALPTAPPPPPLPGLGA 468
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 191 bits (484), Expect = 7e-48
Identities = 173/586 (29%), Positives = 264/586 (45%), Gaps = 70/586 (11%)
Query: 1138 AGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGI------PPPPPLP 1191
A PPPPP PPP LPG+ PPPP PPPPPLP VG PPPPPLP
Sbjct: 418 ASTPPPPP-------PPPLLPGSSAEPPPP------PPPPPLPSVGAKALPTAPPPPPLP 464
Query: 1192 GVGI------PPPPPLPGAGI---PPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSG 1242
G+G P PPPLPG+ PPPPPLPG+G PP P P LP G G PPPP
Sbjct: 465 GLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPP------ 518
Query: 1243 PPLLPQVGSSTLPTPQVCGFLPPPLPSGL-FGLGMNQDKGSRKQPIEPCRPMKPLYWTRI 1301
PPLLP S P V G + + + + GLG + S ++ P MK L W ++
Sbjct: 519 PPLLPCTCS-----PPVAGGMEEVIVAQVDHGLG-SAWVPSHRRVNPPTLRMKKLNWQKL 572
Query: 1302 QLHSKRDSSTSLIWEKIEEPSIDCHE-----FEELFSKTAVKERKKPISDTISKTKAKQV 1356
+ R+ ++ +W + P + E E LFS A K K+P K +
Sbjct: 573 PSNVAREHNS--MWASLSSPDAEAVEPDFSSIERLFSFPAAKP-KEPTMVAPRARKEPKE 629
Query: 1357 VKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIE 1416
+ L K+S + I + +++ + D + D+E L+ L + + E+E +
Sbjct: 630 ITFLDAKKSLNLNIFLKQFKCSNEEVAAMIRAGDTTKFDVEVLKQLLKLLPEKHEIENLR 689
Query: 1417 KHGRSSKDKENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQK 1476
+ +E AK L + F L IP + R+ C+L + + +R K +L+
Sbjct: 690 -----AFTEERAK-LASADHFYLLLLAIPCYQLRIECMLLCEGAAAVLDMVRPKAQLVLA 743
Query: 1477 LCETLKNGPGVMQVLGLVLAFGNYMNGGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLS 1536
CE+L + L+L GN++N G+ T G ADGF + L KL + KS N +LL
Sbjct: 744 ACESLLTSRQLPIFCQLILRIGNFLNYGSHT-GDADGFKISTLLKLTETKSQQNRVTLLH 802
Query: 1537 YIVSYYLRNFDEDAGKEQCLFPLPEPQDLFQASQMKFEDFQKDLRKLKKDLKACEVEAGK 1596
+++ E+A K L P+DL Q SQ + + + +LK +E +
Sbjct: 803 HVL--------EEAEKSHPDL-LQLPRDLEQPSQAAGINLEIIRSEASSNLKKL-LETER 852
Query: 1597 VYQVSSKEHMQPFKENMEQFIIQAKIDQEAEENSLTETHKCFLETTAYFFMKPKLGEKEV 1656
S E + + E ++ I + E E ++ + + + + L +
Sbjct: 853 KVSASVAEVQEQYTERLQASISAFRALDELFE-AIEQKQRELADYLCEDAQQLSLEDTFS 911
Query: 1657 SPNAFFSIWHEFSSDFKDFWKKENKLLLQERVKE-AEEVCRQKKGK 1701
+ AF ++ + KD +KE + R ++ AEE R+ +G+
Sbjct: 912 TMKAFRDLFLRALKENKD--RKEQAAKAERRKQQLAEEEARRPRGE 955
Score = 126 bits (317), Expect = 2e-28
Identities = 74/144 (51%), Positives = 77/144 (53%), Gaps = 39/144 (27%)
Query: 1006 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1065
A PPPPP PPP LPG+ PPPP PPPPPLP G P P P
Sbjct: 418 ASTPPPPP-------PPPLLPGSSAEPPPP------PPPPPLPSVGAKALPTAP-----P 459
Query: 1066 PPPLPGAGI--PPPPPLPGAGIPPPPPLPGAG---IPPPPPLPGVGIPPPPP--LPGAGI 1118
PPPLPG G PP PPL PPPLPG+ PPPPPLPG+G PPPPP LPG G
Sbjct: 460 PPPLPGLGAMAPPAPPL-------PPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGW 512
Query: 1119 PPPPPLPGAGIPPPPPLPGAGIPP 1142
PPP PPPP LP PP
Sbjct: 513 GPPP-------PPPPLLPCTCSPP 529
Score = 125 bits (313), Expect = 5e-28
Identities = 73/141 (51%), Positives = 74/141 (52%), Gaps = 33/141 (23%)
Query: 1061 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP 1120
A PPPPP PPP LPG+ PPPP PPPPPLP VG P P P
Sbjct: 418 ASTPPPPP-------PPPLLPGSSAEPPPP------PPPPPLPSVGAKALPTAP-----P 459
Query: 1121 PPPLPGAGI--PPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPP--LPGAGIPPP 1176
PPPLPG G PP PPLP PP P PPPPPLPG G PPPPP LPG G PP
Sbjct: 460 PPPLPGLGAMAPPAPPLP----PPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPP 515
Query: 1177 PPLPGVGIPPPPPLPGVGIPP 1197
P PPPP LP PP
Sbjct: 516 P-------PPPPLLPCTCSPP 529
Score = 123 bits (309), Expect = 1e-27
Identities = 75/153 (49%), Positives = 78/153 (50%), Gaps = 38/153 (24%)
Query: 942 IPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1001
+ P L A PPPP P PP LPG+ PPPP PPPPPLP G P
Sbjct: 408 VSQPRALEQQASTPPPPPP------PPLLPGSSAEPPPP------PPPPPLPSVGAKALP 455
Query: 1002 PLPGAGIPPPPPLPGAGI--PPPPPLPGAGIPPPPPLPGAG---IPPPPPLPGAGIPPPP 1056
P PPPPLPG G PP PPL PPPLPG+ PPPPPLPG G PPPP
Sbjct: 456 TAP-----PPPPLPGLGAMAPPAPPL-------PPPLPGSCEFLPPPPPPLPGLGCPPPP 503
Query: 1057 P--LPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1087
P LPG G PPP PPPP LP PP
Sbjct: 504 PPLLPGMGWGPPP-------PPPPLLPCTCSPP 529
Score = 123 bits (308), Expect = 2e-27
Identities = 72/140 (51%), Positives = 76/140 (54%), Gaps = 33/140 (23%)
Query: 984 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1043
A PPPPP PPP LPG+ PPPP PPPPPLP G P P P
Sbjct: 418 ASTPPPPP-------PPPLLPGSSAEPPPP------PPPPPLPSVGAKALPTAP-----P 459
Query: 1044 PPPLPGAGI--PPPPPLPGAGIPPPPPLPGAGI---PPPPPLPGAGIPPPPP--LPGAGI 1096
PPPLPG G PP PPLP PPLPG+ PPPPPLPG G PPPPP LPG G
Sbjct: 460 PPPLPGLGAMAPPAPPLP-------PPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGW 512
Query: 1097 -PPPPPLPGVGIPPPPPLPG 1115
PPPPP P + PP+ G
Sbjct: 513 GPPPPPPPLLPCTCSPPVAG 532
Score = 120 bits (301), Expect = 1e-26
Identities = 72/148 (48%), Positives = 77/148 (52%), Gaps = 37/148 (25%)
Query: 896 IPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAI-- 953
+ QP L+ PPPPPP PP LPG+ P PP PPPPPLP
Sbjct: 408 VSQPRALEQQASTPPPPPP--------PPLLPGSSAEPPPP------PPPPPLPSVGAKA 453
Query: 954 ----PPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAG---IPPPPPLPGAGIPPPPP--LP 1004
PPPPPLPG G + PP P P PPPLPG+ PPPPPLPG G PPPPP LP
Sbjct: 454 LPTAPPPPPLPGLG-AMAPPAP----PLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLP 508
Query: 1005 GAGIPPPPPLPGAGIPPPPPLPGAGIPP 1032
G G PPP PPPP LP PP
Sbjct: 509 GMGWGPPP-------PPPPLLPCTCSPP 529
Score = 119 bits (297), Expect = 3e-26
Identities = 74/157 (47%), Positives = 79/157 (50%), Gaps = 46/157 (29%)
Query: 1041 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG----- 1095
+ P L PPPP P PP LPG+ PPPP PPPPPLP G
Sbjct: 408 VSQPRALEQQASTPPPPPP------PPLLPGSSAEPPPP------PPPPPLPSVGAKALP 455
Query: 1096 -IPPPPPLPGVG--IPPPPPLPGAGIPPPPPLPGA--GIPP-PPPLPGAGIPPPPPLPRV 1149
PPPPPLPG+G PP PPL PPPLPG+ +PP PPPLPG G PPP
Sbjct: 456 TAPPPPPLPGLGAMAPPAPPL-------PPPLPGSCEFLPPPPPPLPGLGCPPP------ 502
Query: 1150 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP 1186
PPP LPG G PPP PPPP LP PP
Sbjct: 503 ---PPPLLPGMGWGPPP-------PPPPLLPCTCSPP 529
Score = 112 bits (279), Expect = 4e-24
Identities = 75/204 (36%), Positives = 94/204 (46%), Gaps = 36/204 (17%)
Query: 809 QPPPPP------SLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLP 862
+P P P S+ + Q Q GS P ++ + + + ++A + +
Sbjct: 347 RPRPSPLVKAHKSVQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESIL 406
Query: 863 CTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGI-- 920
++ PPPPPP P LP ++ PPP PPPPPLP G
Sbjct: 407 KVSQPRALEQQASTPPPPPP-----PPLLPGSSAEPPPP--------PPPPPLPSVGAKA 453
Query: 921 ----PPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAI---PPPPPLPGAGIPLPPP--LP 971
PPPPPLPG G + PP P P PPPLPG+ PPPPPLPG G P PPP LP
Sbjct: 454 LPTAPPPPPLPGLGAMA-PPAP----PLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLP 508
Query: 972 GAGI-PPPPPLPGAGIPPPPPLPG 994
G G PPPPP P PP+ G
Sbjct: 509 GMGWGPPPPPPPLLPCTCSPPVAG 532
Score = 101 bits (251), Expect = 7e-21
Identities = 78/241 (32%), Positives = 98/241 (40%), Gaps = 63/241 (26%)
Query: 733 VRHHRILEAKSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPR 792
V+ H+ ++A ++ S T P + G+ P A C + S
Sbjct: 354 VKAHKSVQA-NLDQSQRGSSPQNTTTPKPSVEGQQPAAAAA--------CEPVDHAQSES 404
Query: 793 RISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNS 852
+ V Q+ + PPPPP L +P PP
Sbjct: 405 ILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPP---------------------- 442
Query: 853 CNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGT-EMLPPP 911
PPPLP + + ++P PPPPPLPG+ P A P PPPL G+ E LPPP
Sbjct: 443 -----PPPLP-SVGAKALP----TAPPPPPLPGLGAMAPP--APPLPPPLPGSCEFLPPP 490
Query: 912 PPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLP 971
PPPLPG G PPPPP P LPG G PPP PPPP LP PP+
Sbjct: 491 PPPLPGLGCPPPPP---------PLLPGMGWGPPP-------PPPPLLP---CTCSPPVA 531
Query: 972 G 972
G
Sbjct: 532 G 532
Score = 33.9 bits (76), Expect = 1.4
Identities = 34/147 (23%), Positives = 53/147 (36%), Gaps = 9/147 (6%)
Query: 192 QEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDR 251
QE L ++ + + + + + L + Q L ++ ++P +P+P
Sbjct: 330 QECTLEEVVERLLSVKGRPRPSPLVKAHKSVQANLDQSQRGSSPQNTTTPKPS------- 382
Query: 252 FLLGPSGGAGEAPGSPDTEQALSALS-DLPESLAAEPREPQQPPSPGGLPVSEAPSLPAA 310
+ G A A D Q+ S L P +L + P PP P LP S A P
Sbjct: 383 -VEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPP 441
Query: 311 QPAAKDSPSSTAFPFPEAGPGEEAAGA 337
P S + A P P GA
Sbjct: 442 PPPPLPSVGAKALPTAPPPPPLPGLGA 468
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 182 bits (463), Expect = 2e-45
Identities = 185/584 (31%), Positives = 226/584 (38%), Gaps = 96/584 (16%)
Query: 755 LTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPT-QSISQPPPP 813
L P G RP PP + P + +P ++ S P+ Q++ PP
Sbjct: 304 LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPAT 363
Query: 814 PSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSM--P 871
P P Q P S+ T HS++S + PSP L ++++S+ P
Sbjct: 364 PPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP--PSPLALSSLQATTSLGSP 421
Query: 872 GLG-----MVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPP---PLPGAGIPPP 923
L + P +T P+ P++ P PPLQ LP PP L A P
Sbjct: 422 TLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLS 481
Query: 924 PPLPGAGILPLPPLPG-AGIPPPPPLPGAAIPP--------PPPL--PGAGIPLPPPLPG 972
PL I PL L A P PL +PP PP L P A + PP L
Sbjct: 482 SPLT---IHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPP-LEN 537
Query: 973 AGIPPPPPLPGAGIP--------PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1024
PPPL A P PP P P PP PL PPP P + PPP
Sbjct: 538 LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLT----TPPPETPSSIATPPPQ 593
Query: 1025 LPGAGIPPP------PPLPGAGIPPPPPLPGAGIPP--PPPLPGAGIP------PPPPLP 1070
P A PP PPL PPP P +PP PP P A P P P P
Sbjct: 594 APPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP 653
Query: 1071 GA----------GIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGVGIPP--PPPLPGAG 1117
A PP PP+ PP PP+ + PP P + PP PP P A
Sbjct: 654 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 713
Query: 1118 IPPPPPLPGAGIPP--PPPL--PGAGIPPPPPLPRVGIPPPPPLPGAGIPPP--PPL--- 1168
PP P A PP PPPL P +PP P P PP+ + PPP PPL
Sbjct: 714 ---PPMSPSATPPPQAPPPLAAPPLQVPPSP-------PASPPMSPSATPPPRVPPLLAA 763
Query: 1169 PGAGIPPPP----PLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPP 1224
P +PP P P+ + PPP P + PP LP PP PG P +P+
Sbjct: 764 PPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPS----PPASFPGQA-PFSPSAS 818
Query: 1225 LPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
LP PPP PV PLL QV S +P + PP P
Sbjct: 819 LPMSPLATPPPQAPPVLAAPLL-QVPPSPPASPTLQAPRRPPTP 861
Score = 182 bits (463), Expect = 2e-45
Identities = 182/585 (31%), Positives = 219/585 (37%), Gaps = 102/585 (17%)
Query: 758 PPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPP--- 814
P + LP P PP P + + S + I H T Q PP P
Sbjct: 352 PSLQTLPSPPATPPS--QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLAL 409
Query: 815 -SLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGL 873
SL + G P Q HS T + S++S + + P PPL S + P L
Sbjct: 410 SSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL 469
Query: 874 GM-----VPPPPPPLPGMTVPTLPSTAIPQP---------PPLQGTEMLPPPPPPLPGAG 919
V P PL + L S A P PPL+ L PP P A
Sbjct: 470 QTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPAS 529
Query: 920 IPPPPPLPGAGILPLPPLPGAGIP--------PPPPLPGAAIPPPPPLPGAGIPLPPPLP 971
+ PP L L PPL A P PP P P PP PL PP P
Sbjct: 530 LTTPP-LENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP----PPETP 584
Query: 972 GAGIPPPPPLPGAGIPPP------PPLPGAGIPPPPPLPGAGIPP--PPPLPGAGIP--- 1020
+ PPP P A PP PPL PPP P +PP PP P A P
Sbjct: 585 SSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP 644
Query: 1021 ---PPPPLPGA----------GIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPGAGIPP- 1065
P P P A PP PP+ PP PP+ + PP P PP
Sbjct: 645 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 704
Query: 1066 -PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP--PPPLPGVGIPPPPPLPGAGIPPP- 1121
PP P P PP+ + PPP P PP PP P P PP+ + PPP
Sbjct: 705 QVPPSP----PASPPMSPSATPPPQAPPPLAAPPLQVPPSP----PASPPMSPSATPPPR 756
Query: 1122 -PPL---PGAGIPPPPP--LPGAGIPPPPPLPRVGIPPPP----PLPGAGIPPPPPL-PG 1170
PPL P +PP PP LP + + PPP + PP P P A P P P
Sbjct: 757 VPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 816
Query: 1171 AGIP------PPPPLPGV------GIPPPPPL-PGVGIPPPPPLPGAGIPPPPPLPGMGI 1217
A +P PPP P V +PP PP P + P PP PG P + G +
Sbjct: 817 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG----PDTSVSGPRL 872
Query: 1218 PPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGF 1262
A AP PPP + P L SGP L S+T ++ G+
Sbjct: 873 TLALAPGPPPPPSRSPSSTL---SGPDLAGHSSSATSTPEELRGY 914
Score = 171 bits (433), Expect = 6e-42
Identities = 206/670 (30%), Positives = 242/670 (36%), Gaps = 159/670 (23%)
Query: 743 SIQT-SPTEEGGVLTLPPVDGLPGRPPCPPGAES-------GPQTKFCSEISLIVSPRRI 794
S+QT P + LT P + PP P S G T + L +SPR+
Sbjct: 382 SLQTIPPIQVPHSLTSPSLQA----PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQT 437
Query: 795 SVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHS--------ISTEFQTSHEHSVS 846
L S P++ S PP P L A P S P + +S+ ++S
Sbjct: 438 QASLTS--PSRPASTPPDSPPL--QAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS 493
Query: 847 SAFKNSCNIPSP----PPLPCTESSSSMPGLGMVP-----PP--------PPPLPG---- 885
S +S P PPL T+SS + P L P PP PPPL
Sbjct: 494 SLASHSPQAPLSSLIMPPLE-TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAP 552
Query: 886 MTVPTLPSTAIPQPPPLQGTEM-LPPPPPPLPGAGIPPPPPLPGAGI------LPLPPLP 938
+T P L + P P PLQ L PPP P + PPP P A LP PPL
Sbjct: 553 LTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLS 612
Query: 939 GAGIPPPPPLPGAAIPP--PPPLPGAGIPLPP---PLPGAG------------IPPPPPL 981
PPP P A+PP PP P A PL P P P A PPP P
Sbjct: 613 PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 672
Query: 982 PGAGIPPP--PPLPGAGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLP 1037
A PP PP+ + PP P PP PP P P PP+ + PPP P
Sbjct: 673 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP----PASPPMSPSATPPPQAPP 728
Query: 1038 GAGIPP--PPPLPGAGIPPPPPLPGAGIPPP--PPL---PGAGIPPPPP--LPGAGIPPP 1088
PP PP P P PP+ + PPP PPL P +PP PP LP + + P
Sbjct: 729 PLAAPPLQVPPSP----PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP 784
Query: 1089 PPL--PGAGIPPPPPLPGVGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1145
PP P PP LP PP PG A P LP + + PPP PP
Sbjct: 785 PPQAPPALATPPLQALPS----PPASFPGQAPFSPSASLPMSPLATPPPQA----PPVLA 836
Query: 1146 LPRVGIPPPPPL-PGAGIPPPPPLPG--------------AGIPPPPPL--PGVGIPPPP 1188
P + +PP PP P P PP PG A PPPPP P + P
Sbjct: 837 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD 896
Query: 1189 ---------------------PLPGVGIPPPPPLPGAGIPPP-------PPLPGMGIP-- 1218
P G PPP A P PPL G P
Sbjct: 897 LAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA 956
Query: 1219 PAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSG---LFGLG 1275
P P PP PG+ + GP S P P P P SG G G
Sbjct: 957 PLPWPPATGPGSADGLCTIYETEGP-------ESATPAPGALDPGPSPGTSGGKAAAGAG 1009
Query: 1276 MNQDKGSRKQ 1285
S KQ
Sbjct: 1010 AGASSRSPKQ 1019
Score = 159 bits (401), Expect = 3e-38
Identities = 164/527 (31%), Positives = 202/527 (38%), Gaps = 88/527 (16%)
Query: 795 SVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHS-ISTEFQTSHEHSVSSAFKNSC 853
S L + P+ + ++P PPP +A P + PP ++T + SA +
Sbjct: 301 SSPLATPSPSGTKARPVPPPD---NAATPLPATLPPSPPLATPLPLAPPSP--SAPPSLQ 355
Query: 854 NIPSPPPLPCTESSSSMPGLGMVPPPP-PPLPGMTVP---TLPSTAIPQPP----PLQGT 905
+PSPP P +++ SM M PP +P + VP T PS P P LQ T
Sbjct: 356 TLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQAT 415
Query: 906 EMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGA-AIPPPPPLPGAGI 964
L P + + P A L P P + P PPL ++P PPL +
Sbjct: 416 TSLGSPTLQATHSFLTMSPRQTQAS-LTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLS 474
Query: 965 PLPPPLPG-------------AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1011
P PL A P PL I PP + PP P A + P
Sbjct: 475 PAVSPLSSPLTIHPLQALSSLASHSPQAPLSSL-IMPPLETQSSLAPPSLQTPPASLTTP 533
Query: 1012 PPLPGAGIPPPPPLPGAGIP--------PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1063
P L PPPL A P PP P P PP PL PPP P +
Sbjct: 534 P-LENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLT----TPPPETPSSIA 588
Query: 1064 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP--PPPLPGAGIP-- 1119
PPP P A PPL G P PPL PPP P + +PP PP P A P
Sbjct: 589 TPPPQAPPA--LASPPLQGL---PSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLS 643
Query: 1120 ----PPPPLPGA----------GIPPPPPLPGAGIPP-PPPLPRVGIPP---PPPL--PG 1159
P P P A PP PP+ PP PP+ PP PP L P
Sbjct: 644 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP 703
Query: 1160 AGIPPPPPL-----PGAGIPP--PPPL--PGVGIPPPPPLPGVGIPPPPPLPGAGIPPPP 1210
+PP PP P A PP PPPL P + +PP P P PP+ + PPP
Sbjct: 704 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP-------PASPPMSPSATPPPR 756
Query: 1211 PLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTP 1257
P + PP PP PP + P P PP L LP+P
Sbjct: 757 VPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSP 803
Score = 98.2 bits (243), Expect = 6e-20
Identities = 142/523 (27%), Positives = 167/523 (31%), Gaps = 163/523 (31%)
Query: 889 PTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGIL---------PLP---- 935
P PS A+ + GTE+ P P P A PP P + P P
Sbjct: 169 PGTPSPAMARRSRAAGTEV--GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
Query: 936 -PLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGA--GIPPP--- 989
P G G+ P ++ P P P P A P P P + PP
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 286
Query: 990 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1049
PP A P PL + + P P P PPP A PLP A +PP PPL
Sbjct: 287 PPRKDAA-PALGPLSSSPLATPSPSGTKARPVPPPDNAA-----TPLP-ATLPPSPPL-A 338
Query: 1050 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP----PPL--- 1102
+P PP P A PP L +P PP P + PP P PP PP+
Sbjct: 339 TPLPLAPPSPSA----PPSLQT--LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP 392
Query: 1103 -----PGVGIPPPP-------------------------------------PLPGAGIPP 1120
P + PP P P A PP
Sbjct: 393 HSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPP 452
Query: 1121 --PPPLPGAGIPPPPPLPGAGIP------------------------PPPPLPRVGIPP- 1153
PP +P PPL + P P PL + +PP
Sbjct: 453 DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL 512
Query: 1154 -------PPPL--PGAGI--PP--------PPPLPGAGIP--------PPPPLPGVGIPP 1186
PP L P A + PP PPPL A P PP P P P
Sbjct: 513 ETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAP 572
Query: 1187 PPPLPGVGIPPPPPLPGAGIPPPPPLPG-------MGIPPAPAPPLPPPGTGIPP----P 1235
P PL PPP P + PPP P G+P P PL P PP P
Sbjct: 573 PSPL----TTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALP 628
Query: 1236 PLLPVSGPPLLPQVGSSTLPTPQV----------CGFLPPPLP 1268
PL PP P + P+PQ F PPP P
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 671
Score = 86.3 bits (212), Expect = 2e-16
Identities = 125/440 (28%), Positives = 143/440 (32%), Gaps = 83/440 (18%)
Query: 895 AIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLP----- 949
A + P + +L P PP G+ PPPP P A L L AG PL
Sbjct: 12 AAARTPAARAPGLLTPRPP---GSPRPPPPVTPAA----LRVLGAAGAVGRKPLAERAGG 64
Query: 950 --GAAIPPPPPLPGAGIPLPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPPPLP 1004
GA IP P G P G P PP G G PP + P P
Sbjct: 65 IGGATIPESAPRAG-----PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR 119
Query: 1005 GAGIPPPPPLPGAGI---------------PPPPPLPGAGIPPPPPLPGAGIPPP----- 1044
+G P PL G+ P AG P G P P
Sbjct: 120 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 179
Query: 1045 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGI---------PPPP-----PLPGAGIPPPPP 1090
G + P P P A PP P + P P P G G+ P
Sbjct: 180 SRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 239
Query: 1091 LPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGA--GIPPP---PPLPGAGIPPPPP 1145
+ P P P P A P P P + PP PP A P P
Sbjct: 240 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA-PALGP 298
Query: 1146 LPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAG 1205
L + P P P PPP A PLP +PP PPL +P PP P A
Sbjct: 299 LSSSPLATPSPSGTKARPVPPPDNAA-----TPLPAT-LPPSPPL-ATPLPLAPPSPSA- 350
Query: 1206 IPPPPPLPGMGIPPAPAPPLPPPGTGIPP---PPLLPVSGPPLLPQVGSSTLPTPQVCGF 1262
PP L + PPA P PP PP PP L P +P S T P+ Q
Sbjct: 351 ---PPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPH--SLTSPSLQA--- 402
Query: 1263 LPPPLPSGLFGLGMNQDKGS 1282
PP P L L GS
Sbjct: 403 --PPSPLALSSLQATTSLGS 420
Score = 48.9 bits (115), Expect = 4e-05
Identities = 97/332 (29%), Positives = 120/332 (36%), Gaps = 47/332 (14%)
Query: 232 PAAPPTA--VSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPRE 289
PA+PP + +P P A L LL P SP + S + P S +A P
Sbjct: 637 PASPPLSPLATPSPQAPNALAVHLLQ---APFSPPPSPPVQAPFSPPASPPVSPSATPPS 693
Query: 290 PQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEG 349
Q PPS P+ PS PA+ P SPS+T P P+A P A P++
Sbjct: 694 -QAPPSLAAPPLQVPPSPPASPPM---SPSAT--PPPQAPP--PLAAPPLQVPPSPPASP 745
Query: 350 EEDAFEDAPRGSPGEEWAP--EVGEDAPQRLGEEP--EEEAQGPDA---PAAASLPGSPA 402
P P AP +V P L P + Q P A P +LP PA
Sbjct: 746 PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPA 805
Query: 403 --PSQRCFKPYPLITPCYIKTTTRQ---------LSSPNHSPSQSPNQSPRIKRRPEPSL 451
P Q F P + + T Q L P P+ Q+PR P P
Sbjct: 806 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 865
Query: 452 S-RGSRTALASVAAP------AKKHRADGGLAAGLSRSADWT-EEL-GARTPRVGGS--- 499
S G R LA P + G AG S SA T EEL G + GG+
Sbjct: 866 SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS 925
Query: 500 ----AHLLERGVASDSGGGVSPALAAKASGAP 527
A L A+ S G P A GAP
Sbjct: 926 PPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 957
Score = 42.0 bits (97), Expect = 0.005
Identities = 85/325 (26%), Positives = 118/325 (36%), Gaps = 47/325 (14%)
Query: 232 PAAPPTAVS----PQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEP 287
PA+PP + S PQ L + PS P SP + + +P LAA P
Sbjct: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPS-----PPASPPMSPSATPPPRVPPLLAAPP 765
Query: 288 REPQQPPSP-GGLPVSEAPSLPAAQPAAKDSPSSTAFP-----FPEAGPGEEAAGAPVRG 341
Q PPSP LP+S P P A +P A P FP P +A P+
Sbjct: 766 L--QVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 823
Query: 342 AGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEE-PEEEAQGPDAPAAASLPGS 400
+ + P +P + AP+R P+ GP A + PG
Sbjct: 824 LATPPPQAPPVLAAPLLQVPPSPPASPTL--QAPRRPPTPGPDTSVSGPRLTLALA-PGP 880
Query: 401 PAPSQRCFKPYPLIT-------PCYIKTTTRQL----SSPNHSPSQSPNQSPRIKRRPEP 449
P P R P ++ +T +L S P + SP +
Sbjct: 881 PPPPSR--SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA 938
Query: 450 SLSRGSRTALA---SVAAPAKKHRADG-GLAAGLSRSADWTEELGARTPRVGGSAHLLER 505
+ SRG LA + AP A G G A GL + TE + TP G L+
Sbjct: 939 AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYE-TEGPESATPAPGA----LDP 993
Query: 506 GVASDSGGGVSPALAAKASGAPAAA 530
G + + GG AA +GA A++
Sbjct: 994 GPSPGTSGG----KAAAGAGAGASS 1014
Score = 40.0 bits (92), Expect = 0.020
Identities = 65/271 (23%), Positives = 94/271 (34%), Gaps = 37/271 (13%)
Query: 200 QQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQP---------GAFLGLD 250
Q+ +R+ ++ + ++ GA + PT +P P G +GL
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 190
Query: 251 RFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREP--QQPPSPGGLPVSEAPSLP 308
R A A P TE ++S E EP ++P + GGL
Sbjct: 191 R-------PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL--------- 234
Query: 309 AAQPAAKDSPSSTAFPFPE-AGPGEEAAGAPVRGAGDTDEEGEE-DAFEDAPRGSPGEEW 366
Q A S SS+A P A G A G P A + + + A P ++
Sbjct: 235 --QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292
Query: 367 APEVGEDAPQRLGEEPEEEAQGPDAP----AAASLPGSPAPSQRCFKPYPLITPCYIKTT 422
AP +G + L + P AA LP + PS P PL P
Sbjct: 293 APALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPP 352
Query: 423 TRQL--SSPNHSPSQSPNQSPRIKRRPEPSL 451
+ Q S P PSQ+P + PSL
Sbjct: 353 SLQTLPSPPATPPSQAPPSMTTPPMQAPPSL 383
Score = 36.6 bits (83), Expect = 0.22
Identities = 53/201 (26%), Positives = 75/201 (37%), Gaps = 20/201 (9%)
Query: 265 GSPDTEQALSALSDLPESLAAEPREPQQPPS-PGGLPVSEAP-SLPAAQPAAKD-SPSST 321
GSP + S L+ P A P +P S P P +AP SLPA+ P SP+ +
Sbjct: 419 GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVS 478
Query: 322 AFPFPE--------AGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGED 373
P + + AP+ E + + + P P + E+
Sbjct: 479 PLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPL-EN 537
Query: 374 APQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSP 433
P L P + A P P PAP P PL TP T +++P P
Sbjct: 538 LPS-LAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP--PPETPSSIATP---P 591
Query: 434 SQSPN--QSPRIKRRPEPSLS 452
Q+P SP ++ P P LS
Sbjct: 592 PQAPPALASPPLQGLPSPPLS 612
Score = 35.8 bits (81), Expect = 0.37
Identities = 54/205 (26%), Positives = 63/205 (30%), Gaps = 34/205 (16%)
Query: 226 LQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPG--------------SPDTEQ 271
LQ P A PT +P+ G D + GP APG PD
Sbjct: 840 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 899
Query: 272 ALSALSDLPESLAAEPREPQQPPSPGGLPVSEAP--SLPAAQPAAKDSPSSTAFPFPEAG 329
S+ + PE L P+ GG S P L A PAA + F
Sbjct: 900 HSSSATSTPEELRGYDSGPE-----GGAAASPPPDAELAACHPAAWSRGPAPPLAF-RGA 953
Query: 330 PGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGP 389
PG P G G D G +E PE AP L P G
Sbjct: 954 PGAPLPWPPATGPGSAD--GLCTIYETE---------GPESATPAPGALDPGPSPGTSGG 1002
Query: 390 DAPAAASL-PGSPAPSQRCFKPYPL 413
A A A S +P Q PL
Sbjct: 1003 KAAAGAGAGASSRSPKQARLGELPL 1027
Score = 32.3 bits (72), Expect = 4.1
Identities = 47/185 (25%), Positives = 54/185 (29%), Gaps = 10/185 (5%)
Query: 263 APGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSL----PAAQPAAKDSP 318
AP T A L P Q PPSP P E PS P P A SP
Sbjct: 542 APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP 601
Query: 319 SSTAFPFPEAGP--GEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQ 376
P P P P A +P SP +P+
Sbjct: 602 PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA---SPPLSPLATPSPQAPNALAV 658
Query: 377 RLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQS 436
L + P P A S P SP P P P + SP SP S
Sbjct: 659 HLLQAPFSPPPSPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 717
Query: 437 PNQSP 441
P+ +P
Sbjct: 718 PSATP 722
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 182 bits (463), Expect = 2e-45
Identities = 184/654 (28%), Positives = 261/654 (39%), Gaps = 121/654 (18%)
Query: 1045 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI-----PPPPPLPGAGIPPP 1099
PP P P P P A L G+ PG + P P G P
Sbjct: 459 PPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPT 518
Query: 1100 PPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPG 1159
P +P G P P P A P PGA PPPPPLPG +P P P P PPLPG
Sbjct: 519 PGVP-TGSPSPDLAPAA-----EPAPGAAPPPPPPLPG--LPSPQEAPPSAPPQAPPLPG 570
Query: 1160 AGIPPP-PPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIP 1218
+ PPP PPLPG +PPPP PPPPP PG P PPP PPPPP
Sbjct: 571 SPEPPPAPPLPG-DLPPPP-------PPPPPPPGTDGPVPPP------PPPPP------- 609
Query: 1219 PAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQ 1278
PPPG PP L L P V
Sbjct: 610 -------PPPG---GPPDALGRRDSELGPGV----------------------------- 630
Query: 1279 DKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSSTSLIWEKIEEPSI----DCHEFEELFSK 1334
K+PI+ M L W + K T ++ ++ + + D +FEE F K
Sbjct: 631 ---KAKKPIQTKFRMPLLNWVAL----KPSQITGTVFTELNDEKVLQELDMSDFEEQF-K 682
Query: 1335 TAVKERKKPISDTISKT--KAKQVVKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNS 1392
T + +S SK KA L+ R++ + I + +L + I A+ D
Sbjct: 683 TKSQGPSLDLSALKSKAAQKAPSKATLIEANRAKNLAITLRKGNLGAERICQAIEAYDLQ 742
Query: 1393 VVDLETLQALYENRAQSDELEKIEKHGRSSKDKENAKSLDKPEQFLYELSLIPNFSERVF 1452
+ L+ L+ L E I + R + E L + ++F+ S IP ER+
Sbjct: 743 ALGLDFLELLMRFLPTEYERSLITRFEREQRPME---ELSEEDRFMLCFSRIPRLPERMT 799
Query: 1453 CILFQSTFSESICSIRRKLELLQKLCETLKNGPGVMQVLGLVLAFGNYMNGGNKTRGQAD 1512
+ F F ++ + +L + ++K+ + Q+L +VLAFGNYMN + RG A
Sbjct: 800 TLTFLGNFPDTAQLLMPQLNAIIAASMSIKSSDKLRQILEIVLAFGNYMN--SSKRGAAY 857
Query: 1513 GFGLDILPKLKDVKSSDNSRSLLSYIVSYYLRNFDEDAGKEQCLFPLPEPQDLFQASQMK 1572
GF L L L ++KS+D ++LL Y+V + + G L L +A +
Sbjct: 858 GFRLQSLDALLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDL------HFLDKAGSVS 911
Query: 1573 FEDFQKDLRKLKKDLKACEVEAGKVYQ-VSSKEHMQPFKENMEQFIIQAKIDQEAEENSL 1631
+ D+R L++ L+ + E + + KE ++ M++ + +K QEA
Sbjct: 912 LDSVLADVRSLQRGLELTQREFVRQDDCMVLKEFLRANSPTMDKLLADSKTAQEA----- 966
Query: 1632 TETHKCFLETTAYFFMKPKLGEKEVSPNAFFSIWHEFSSDFK------DFWKKE 1679
F YF P K SP FFS++ F +K + WKKE
Sbjct: 967 ------FESVVEYFGENP----KTTSPGLFFSLFSRFIKAYKKAEQEVEQWKKE 1010
Score = 112 bits (280), Expect = 3e-24
Identities = 78/196 (39%), Positives = 89/196 (45%), Gaps = 29/196 (14%)
Query: 903 QGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGA 962
+ T M PP P P P P A L + L G+ PG A+
Sbjct: 449 ESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEI----- 503
Query: 963 GIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1022
+P+ P G P P +P G P P P A P PGA PPPPPLPG +P P
Sbjct: 504 -LPVAVATPSGGDAPTPGVP-TGSPSPDLAPAA-----EPAPGAAPPPPPPLPG--LPSP 554
Query: 1023 PPLPGAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1081
P + P PPLPG+ PPP PPLPG +PPPPP PPPP PG P PPP
Sbjct: 555 QEAPPSAPPQAPPLPGSPEPPPAPPLPG-DLPPPPP-------PPPPPPGTDGPVPPP-- 604
Query: 1082 GAGIPPPPPLPGAGIP 1097
PPPPP P G P
Sbjct: 605 ----PPPPPPPPGGPP 616
Score = 110 bits (274), Expect = 2e-23
Identities = 77/192 (40%), Positives = 88/192 (45%), Gaps = 30/192 (15%)
Query: 866 SSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGT---EMLPPPPPPLPGAGIPP 922
S S+ G PP P P PT PS + L+ +L P + +P
Sbjct: 448 SESTAMGASRRPPEPEKAPP-AAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPV 506
Query: 923 PPPLPGAGILPLPPLPGAGIPPPP------PLPGAAIPPPPPLPGAGIPLPPPLPGAGIP 976
P G P P +P G P P P PGAA PPPPPLPG +P P P + P
Sbjct: 507 AVATPSGGDAPTPGVP-TGSPSPDLAPAAEPAPGAAPPPPPPLPG--LPSPQEAPPSAPP 563
Query: 977 PPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1035
PPLPG+ PPP PPLPG PPPPP PPPPP +PPPP PPPPP
Sbjct: 564 QAPPLPGSPEPPPAPPLPGDLPPPPPP------PPPPPGTDGPVPPPP-------PPPPP 610
Query: 1036 LPGAGIPPPPPL 1047
PG PP L
Sbjct: 611 PPGG---PPDAL 619
Score = 109 bits (273), Expect = 2e-23
Identities = 76/187 (40%), Positives = 83/187 (44%), Gaps = 30/187 (16%)
Query: 968 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI-----PPPPPLPGAGIPPP 1022
PP P P P P A L G+ PG + P P G P
Sbjct: 459 PPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPT 518
Query: 1023 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1082
P +P G P P P A P PGA PPPPPLPG +P P P + P PPLPG
Sbjct: 519 PGVP-TGSPSPDLAPAA-----EPAPGAAPPPPPPLPG--LPSPQEAPPSAPPQAPPLPG 570
Query: 1083 AGIPPP-PPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1141
+ PPP PPLPG PPPPP PPPPP +PPPP PPPPP PG
Sbjct: 571 SPEPPPAPPLPGDLPPPPPP------PPPPPGTDGPVPPPP-------PPPPPPPGG--- 614
Query: 1142 PPPPLPR 1148
PP L R
Sbjct: 615 PPDALGR 621
Score = 109 bits (273), Expect = 2e-23
Identities = 76/185 (41%), Positives = 83/185 (44%), Gaps = 30/185 (16%)
Query: 946 PPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGI-----PPPPPLPGAGIPPP 1000
PP P A P P P A L G+ PG + P P G P
Sbjct: 459 PPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPT 518
Query: 1001 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1060
P +P G P P P A P PGA PPPPPLPG +P P P + P PPLPG
Sbjct: 519 PGVP-TGSPSPDLAPAA-----EPAPGAAPPPPPPLPG--LPSPQEAPPSAPPQAPPLPG 570
Query: 1061 AGIPPP-PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIP 1119
+ PPP PPLPG PPPPP PPPPP +PPPP PPPPP PG
Sbjct: 571 SPEPPPAPPLPGDLPPPPPP------PPPPPGTDGPVPPPP-------PPPPPPPGG--- 614
Query: 1120 PPPPL 1124
PP L
Sbjct: 615 PPDAL 619
Score = 108 bits (271), Expect = 3e-23
Identities = 72/176 (40%), Positives = 79/176 (44%), Gaps = 27/176 (15%)
Query: 935 PPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGI-----PPPPPLPGAGIPPP 989
PP P P P P A L G+ PG + P P G P
Sbjct: 459 PPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPT 518
Query: 990 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1049
P +P G P P P A P PGA PPPPPLPG +P P P + P PPLPG
Sbjct: 519 PGVP-TGSPSPDLAPAA-----EPAPGAAPPPPPPLPG--LPSPQEAPPSAPPQAPPLPG 570
Query: 1050 AGIPPP-PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1104
+ PPP PPLPG PPPPP PPPPP +PPPP PPPPP PG
Sbjct: 571 SPEPPPAPPLPGDLPPPPPP------PPPPPGTDGPVPPPP-------PPPPPPPG 613
Score = 107 bits (268), Expect = 8e-23
Identities = 72/176 (40%), Positives = 79/176 (44%), Gaps = 27/176 (15%)
Query: 1012 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI-----PPPPPLPGAGIPPP 1066
PP P P P P A L G+ PG + P P G P
Sbjct: 459 PPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPT 518
Query: 1067 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPG 1126
P +P G P P P A P PGA PPPPPLPG +P P P + P PPLPG
Sbjct: 519 PGVP-TGSPSPDLAPAA-----EPAPGAAPPPPPPLPG--LPSPQEAPPSAPPQAPPLPG 570
Query: 1127 AGIPPP-PPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1181
+ PPP PPLPG PPPPP PPPPP +PPPP PPPPP PG
Sbjct: 571 SPEPPPAPPLPGDLPPPPPP------PPPPPGTDGPVPPPP-------PPPPPPPG 613
Score = 105 bits (263), Expect = 3e-22
Identities = 75/185 (40%), Positives = 81/185 (43%), Gaps = 30/185 (16%)
Query: 1001 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI-----PPPPPLPGAGIPPP 1055
PP P P P P A L G+ PG + P P G P
Sbjct: 459 PPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPT 518
Query: 1056 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPG 1115
P +P G P P P A P PGA PPPPPLPG +P P P P PPLPG
Sbjct: 519 PGVP-TGSPSPDLAPAA-----EPAPGAAPPPPPPLPG--LPSPQEAPPSAPPQAPPLPG 570
Query: 1116 AGIPPP-PPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIP 1174
+ PPP PPLPG PPPPP PPPPP +PPPP PPPPP PG
Sbjct: 571 SPEPPPAPPLPGDLPPPPPP------PPPPPGTDGPVPPPP-------PPPPPPPGG--- 614
Query: 1175 PPPPL 1179
PP L
Sbjct: 615 PPDAL 619
Score = 92.8 bits (229), Expect = 3e-18
Identities = 70/202 (34%), Positives = 85/202 (42%), Gaps = 36/202 (17%)
Query: 800 SHQPTQSISQPPPPPSLLWSAGQGQPGSQP--PHSISTEFQTSHEHSVSSAFKNSCNIPS 857
S S+ PP P + P + P P ++ + + E + + + S
Sbjct: 448 SESTAMGASRRPPEP-------EKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVS 500
Query: 858 PPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPG 917
LP ++ P G P P P G P L A P P PPPPPPLPG
Sbjct: 501 IEILPVAVAT---PSGGDAPTPGVPT-GSPSPDLAPAAEPAPGAA------PPPPPPLPG 550
Query: 918 AGIPPPPPLPGAGILPLPPLPGAGIPPP-PPLPGAAIPPPPPLPGAGIPLPPPLPGAGIP 976
+P P P + PPLPG+ PPP PPLPG PPPPP PPP PG P
Sbjct: 551 --LPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPP--------PPPPPGTDGP 600
Query: 977 PPPPLPGAGIPPPPPLPGAGIP 998
PPP PPPPP P G P
Sbjct: 601 VPPP------PPPPPPPPGGPP 616
Score = 72.0 bits (175), Expect = 5e-12
Identities = 85/324 (26%), Positives = 116/324 (35%), Gaps = 97/324 (29%)
Query: 642 ETESQSAVSETPQKRSDAVQKEVVDMKSEGQATVIQQLEQTIEDLRTKIAELERQYPALD 701
+TE+++AV E ++ + V A + ++L + KIAELE+Q
Sbjct: 390 DTETKNAVLEHMEELQEQV------------ALLTERLRDAENESMAKIAELEKQLSQAR 437
Query: 702 TEVASGHQGLENGVTASGDVCLEALRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPPVD 761
E+ + + TA G E+ A ++ EE G++ +
Sbjct: 438 KELETLRERFSES-TAMG-ASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRI---- 491
Query: 762 GLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAG 821
L G PG +S+ + P ++ PT + P P L A
Sbjct: 492 -LRG-----PG----------DAVSIEILPVAVATPSGGDAPTPGVPTGSPSPDLA-PAA 534
Query: 822 QGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPP 881
+ PG+ P P PPPLP S P PP P
Sbjct: 535 EPAPGAAP--------------------------PPPPPLPGLPSPQEAP--PSAPPQAP 566
Query: 882 PLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAG 941
PLPG P+PPP PPLPG +PPPPP P PP PG
Sbjct: 567 PLPGS----------PEPPP----------APPLPG-DLPPPPP-------PPPPPPGTD 598
Query: 942 IPPPPPLPGAAIPPPPPLPGAGIP 965
P PPP PPPPP P G P
Sbjct: 599 GPVPPP------PPPPPPPPGGPP 616
Score = 38.9 bits (89), Expect = 0.044
Identities = 33/108 (30%), Positives = 37/108 (34%), Gaps = 12/108 (11%)
Query: 233 AAPPTAVSPQPGAFLGLDRFLLGPSG--GAGEAPGSPDTEQALSALSDLPES-------L 283
A P +P PG G L P+ G AP P L + + P S L
Sbjct: 509 ATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPL 568
Query: 284 AAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPG 331
P P PP PG LP P P P D P P P PG
Sbjct: 569 PGSPEPPPAPPLPGDLP---PPPPPPPPPPGTDGPVPPPPPPPPPPPG 613
Score = 37.0 bits (84), Expect = 0.17
Identities = 35/112 (31%), Positives = 39/112 (34%), Gaps = 12/112 (10%)
Query: 226 LQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAP---GSPDTEQALSALSDLPES 282
L A EPA P A P P GL P +AP GSP+ A DLP
Sbjct: 530 LAPAAEPA--PGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPP 587
Query: 283 LAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEA 334
P PP P G P P P P + E GPG +A
Sbjct: 588 -------PPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSELGPGVKA 632
Score = 32.7 bits (73), Expect = 3.1
Identities = 36/159 (22%), Positives = 50/159 (31%), Gaps = 41/159 (25%)
Query: 291 QQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGE 350
++PP P P + AP+ P+A + GPG+ A + G
Sbjct: 457 RRPPEPEKAPPA-APTRPSALELKVEELEEKGLIRILRGPGD-AVSIEILPVAVATPSGG 514
Query: 351 EDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKP 410
+ P GSP + AP E A G P LPG P
Sbjct: 515 DAPTPGVPTGSPSPDLAPAA-------------EPAPGAAPPPPPPLPGLP--------- 552
Query: 411 YPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEP 449
SP +P +P Q+P + PEP
Sbjct: 553 -----------------SPQEAPPSAPPQAPPLPGSPEP 574
>gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]
Length = 1096
Score = 180 bits (456), Expect = 1e-44
Identities = 161/566 (28%), Positives = 259/566 (45%), Gaps = 85/566 (15%)
Query: 1171 AGIPPPP---PLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGM-GIPPAPAPPLP 1226
+GIP PP PLPGVG PPPPP P +P PLP PPPPPLPGM GIPP
Sbjct: 546 SGIPGPPAAPPLPGVGPPPPPPAPP--LPGGAPLP----PPPPPLPGMMGIPP------- 592
Query: 1227 PPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSR-KQ 1285
PPPP L GPP P P + G PPP G+ +N G + K+
Sbjct: 593 ------PPPPPLLFGGPP----------PPPPLGGVPPPP------GISLNLPYGMKQKK 630
Query: 1286 PIEPCRPMKPLYWTRIQLHSKRDSSTSLIWEKIEEPSIDCHEFEELFSK------TAVKE 1339
+P MK + W++I+ + S + W +++E D E +LF+K T +K
Sbjct: 631 MYKPEVSMKRINWSKIE---PTELSENCFWLRVKE---DKFENPDLFAKLALNFATQIKV 684
Query: 1340 RKKPISDTISKT----KAKQVVKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVD 1395
+K + KT K + +++L K +Q + I + S + +DI++ ++ ++ ++
Sbjct: 685 QKNAEALEEKKTGPTKKKVKELRILDPKTAQNLSIFLGSYRMPYEDIRNVILEVNEDMLS 744
Query: 1396 LETLQALYENRAQSDELEKIEKHGRSSKDKENAKSLDKPEQFLYELSLIPNFSERVFCIL 1455
+Q L ++ + L ++ ++ K L +PEQF +S + R+ IL
Sbjct: 745 EALIQNLVKHLPEQKILNEL------AELKNEYDDLCEPEQFGVVMSSVKMLQPRLSSIL 798
Query: 1456 FQSTFSESICSIRRKLELLQKLCETLKNGPGVMQVLGLVLAFGNYMNGGNKTRGQADGFG 1515
F+ TF E I +I+ + + CE LK ++L LVL GNYMN G++ Q+ GF
Sbjct: 799 FKLTFEEHINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNYMNSGSR-NAQSLGFK 857
Query: 1516 LDILPKLKDVKSSDNSRSLLSYIVSYYLRNFDEDAGKEQCLFPLPEPQDLFQASQMKFED 1575
++ L K++D KS+D +LL +++ + E+ ++ FP E + + AS++ +
Sbjct: 858 INFLCKIRDTKSADQKTTLL-----HFIADICEEKYRDILKFP-EELEHVESASKVSAQI 911
Query: 1576 FQKDLRKLKKDLKACEVEAGKVYQVSSKEHMQPFKENMEQFIIQAKIDQEAEENSLTETH 1635
+ +L +++ + E + K Q ++ F E M F A+ E
Sbjct: 912 LKSNLASMEQQIVHLERDIKKFPQAENQH--DKFVEKMTSFTKTAREQYEKLSTMHNNMM 969
Query: 1636 KCFLETTAYFFMKPKLGEKEVSPNAFFSIWHEFSSDFKDFWKKENK----------LLLQ 1685
K + YF K VS FF + F + F + ++ NK L
Sbjct: 970 KLYENLGEYFI----FDSKTVSIEEFFGDLNNFRTLFLEAVRENNKRREMEEKTRRAKLA 1025
Query: 1686 ERVKEAEEVCRQKKGKSLYKIKPRHD 1711
+ E E++ RQKK K L I D
Sbjct: 1026 KEKAEQEKLERQKKKKQLIDINKEGD 1051
Score = 90.5 bits (223), Expect = 1e-17
Identities = 55/107 (51%), Positives = 57/107 (53%), Gaps = 37/107 (34%)
Query: 918 AGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPP 977
+GIP PP P PLPG G PPPPP P PLPG G PLP PP
Sbjct: 546 SGIPGPPAAP--------PLPGVGPPPPPPAP--------PLPG-GAPLP--------PP 580
Query: 978 PPPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1023
PPPLPG GIPP PPPPPL G PPPPPL G+PPPP
Sbjct: 581 PPPLPGMMGIPP---------PPPPPLLFGGPPPPPPL--GGVPPPP 616
Score = 89.4 bits (220), Expect = 3e-17
Identities = 47/79 (59%), Positives = 50/79 (63%), Gaps = 14/79 (17%)
Query: 1094 AGIPPPP---PLPGVGIPPPPPLPGAGIPPPPPLPGAG--IPPPPPLPG-AGIPPPPPLP 1147
+GIP PP PLPGVG PPPPP P PLPG PPPPPLPG GIPPPPP P
Sbjct: 546 SGIPGPPAAPPLPGVGPPPPPPAP--------PLPGGAPLPPPPPPLPGMMGIPPPPPPP 597
Query: 1148 RVGIPPPPPLPGAGIPPPP 1166
+ PPPP P G+PPPP
Sbjct: 598 LLFGGPPPPPPLGGVPPPP 616
Score = 88.6 bits (218), Expect = 5e-17
Identities = 50/88 (56%), Positives = 53/88 (60%), Gaps = 21/88 (23%)
Query: 973 AGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPLPGA 1028
+GIP PP PLPG G PPPPP P +P PLP PPPPPLPG GIPP
Sbjct: 546 SGIPGPPAAPPLPGVGPPPPPPAPP--LPGGAPLP----PPPPPLPGMMGIPP------- 592
Query: 1029 GIPPPPPLPGAGIPPPPPLPGAGIPPPP 1056
PPPPPL G PPPPPL G+PPPP
Sbjct: 593 --PPPPPLLFGGPPPPPPL--GGVPPPP 616
Score = 88.6 bits (218), Expect = 5e-17
Identities = 53/99 (53%), Positives = 55/99 (55%), Gaps = 32/99 (32%)
Query: 995 AGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-A 1050
+GIP PP PLPG G PPPPP P PLPG PLP PPPPPLPG
Sbjct: 546 SGIPGPPAAPPLPGVGPPPPPPAP--------PLPGGA-----PLP----PPPPPLPGMM 588
Query: 1051 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1089
GIPPPP PPPL G PPPPPL G+PPPP
Sbjct: 589 GIPPPP---------PPPLLFGGPPPPPPL--GGVPPPP 616
Score = 88.6 bits (218), Expect = 5e-17
Identities = 50/88 (56%), Positives = 53/88 (60%), Gaps = 21/88 (23%)
Query: 1050 AGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPLPGV 1105
+GIP PP PLPG G PPPPP P +P PLP PPPPPLPG GIPPPP
Sbjct: 546 SGIPGPPAAPPLPGVGPPPPPPAPP--LPGGAPLP----PPPPPLPGMMGIPPPP----- 594
Query: 1106 GIPPPPPLPGAGIPPPPPLPGAGIPPPP 1133
PPPL G PPPPPL G+PPPP
Sbjct: 595 ----PPPLLFGGPPPPPPL--GGVPPPP 616
Score = 88.2 bits (217), Expect = 6e-17
Identities = 48/84 (57%), Positives = 50/84 (59%), Gaps = 18/84 (21%)
Query: 963 GIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPLPGAGIPP 1021
G P PPLPG G PPPPP P +P PLP PPPPPLPG GIPP PP
Sbjct: 550 GPPAAPPLPGVGPPPPPPAPP--LPGGAPLP----PPPPPLPGMMGIPP---------PP 594
Query: 1022 PPPLPGAGIPPPPPLPGAGIPPPP 1045
PPPL G PPPPPL G+PPPP
Sbjct: 595 PPPLLFGGPPPPPPL--GGVPPPP 616
Score = 87.8 bits (216), Expect = 8e-17
Identities = 50/88 (56%), Positives = 53/88 (60%), Gaps = 21/88 (23%)
Query: 1072 AGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPG-AGIPPPPPLPGA 1127
+GIP PP PLPG G PPPPP P +P PLP PPPPPLPG GIPP
Sbjct: 546 SGIPGPPAAPPLPGVGPPPPPPAPP--LPGGAPLP----PPPPPLPGMMGIPP------- 592
Query: 1128 GIPPPPPLPGAGIPPPPPLPRVGIPPPP 1155
PPPPPL G PPPPPL G+PPPP
Sbjct: 593 --PPPPPLLFGGPPPPPPLG--GVPPPP 616
Score = 87.4 bits (215), Expect = 1e-16
Identities = 53/103 (51%), Positives = 57/103 (55%), Gaps = 24/103 (23%)
Query: 866 SSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPG-AGIPPPP 924
SSS +PG PP PPLPG+ P P PPL G LPPPPPPLPG GIPPPP
Sbjct: 544 SSSGIPG----PPAAPPLPGVGPPPPPPA-----PPLPGGAPLPPPPPPLPGMMGIPPPP 594
Query: 925 PLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLP 967
P PPL G PPPPPL G +PPP PG + LP
Sbjct: 595 P---------PPLLFGGPPPPPPLGG--VPPP---PGISLNLP 623
Score = 87.4 bits (215), Expect = 1e-16
Identities = 53/99 (53%), Positives = 55/99 (55%), Gaps = 32/99 (32%)
Query: 1028 AGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-A 1083
+GIP PP PLPG G PPPPP P PLPG PLP PPPPPLPG
Sbjct: 546 SGIPGPPAAPPLPGVGPPPPPPAP--------PLPGGA-----PLP----PPPPPLPGMM 588
Query: 1084 GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPP 1122
GIPPPP PPPL G PPPPPL G+PPPP
Sbjct: 589 GIPPPP---------PPPLLFGGPPPPPPL--GGVPPPP 616
Score = 87.4 bits (215), Expect = 1e-16
Identities = 48/85 (56%), Positives = 49/85 (57%), Gaps = 22/85 (25%)
Query: 909 PPPPPPLPGAGIPPPPPLPGAGILPLP---PLPGAGIPPPPPLPGAAIPPPPPLPGAGIP 965
PP PPLPG G PPPPP P PLP PLP PPPPPLPG PPPP
Sbjct: 551 PPAAPPLPGVGPPPPPPAP-----PLPGGAPLP----PPPPPLPGMMGIPPPP------- 594
Query: 966 LPPPLPGAGIPPPPPLPGAGIPPPP 990
PPPL G PPPPPL G+PPPP
Sbjct: 595 -PPPLLFGGPPPPPPL--GGVPPPP 616
Score = 53.5 bits (127), Expect = 2e-06
Identities = 43/143 (30%), Positives = 48/143 (33%), Gaps = 75/143 (52%)
Query: 803 PTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLP 862
P + PPPPP+ PPLP
Sbjct: 556 PLPGVGPPPPPPA-------------------------------------------PPLP 572
Query: 863 CTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPP 922
G +PPPPPPLPGM IP PPPPPPL G PP
Sbjct: 573 ---------GGAPLPPPPPPLPGM-------MGIP-----------PPPPPPLLFGGPPP 605
Query: 923 PPPLPGAGILPLPPLPGAGIPPP 945
PPPL G +PP PG + P
Sbjct: 606 PPPLGG-----VPPPPGISLNLP 623
>gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]
Length = 1101
Score = 180 bits (456), Expect = 1e-44
Identities = 161/566 (28%), Positives = 259/566 (45%), Gaps = 85/566 (15%)
Query: 1171 AGIPPPP---PLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGM-GIPPAPAPPLP 1226
+GIP PP PLPGVG PPPPP P +P PLP PPPPPLPGM GIPP
Sbjct: 546 SGIPGPPAAPPLPGVGPPPPPPAPP--LPGGAPLP----PPPPPLPGMMGIPP------- 592
Query: 1227 PPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSR-KQ 1285
PPPP L GPP P P + G PPP G+ +N G + K+
Sbjct: 593 ------PPPPPLLFGGPP----------PPPPLGGVPPPP------GISLNLPYGMKQKK 630
Query: 1286 PIEPCRPMKPLYWTRIQLHSKRDSSTSLIWEKIEEPSIDCHEFEELFSK------TAVKE 1339
+P MK + W++I+ + S + W +++E D E +LF+K T +K
Sbjct: 631 MYKPEVSMKRINWSKIE---PTELSENCFWLRVKE---DKFENPDLFAKLALNFATQIKV 684
Query: 1340 RKKPISDTISKT----KAKQVVKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVD 1395
+K + KT K + +++L K +Q + I + S + +DI++ ++ ++ ++
Sbjct: 685 QKNAEALEEKKTGPTKKKVKELRILDPKTAQNLSIFLGSYRMPYEDIRNVILEVNEDMLS 744
Query: 1396 LETLQALYENRAQSDELEKIEKHGRSSKDKENAKSLDKPEQFLYELSLIPNFSERVFCIL 1455
+Q L ++ + L ++ ++ K L +PEQF +S + R+ IL
Sbjct: 745 EALIQNLVKHLPEQKILNEL------AELKNEYDDLCEPEQFGVVMSSVKMLQPRLSSIL 798
Query: 1456 FQSTFSESICSIRRKLELLQKLCETLKNGPGVMQVLGLVLAFGNYMNGGNKTRGQADGFG 1515
F+ TF E I +I+ + + CE LK ++L LVL GNYMN G++ Q+ GF
Sbjct: 799 FKLTFEEHINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNYMNSGSR-NAQSLGFK 857
Query: 1516 LDILPKLKDVKSSDNSRSLLSYIVSYYLRNFDEDAGKEQCLFPLPEPQDLFQASQMKFED 1575
++ L K++D KS+D +LL +++ + E+ ++ FP E + + AS++ +
Sbjct: 858 INFLCKIRDTKSADQKTTLL-----HFIADICEEKYRDILKFP-EELEHVESASKVSAQI 911
Query: 1576 FQKDLRKLKKDLKACEVEAGKVYQVSSKEHMQPFKENMEQFIIQAKIDQEAEENSLTETH 1635
+ +L +++ + E + K Q ++ F E M F A+ E
Sbjct: 912 LKSNLASMEQQIVHLERDIKKFPQAENQH--DKFVEKMTSFTKTAREQYEKLSTMHNNMM 969
Query: 1636 KCFLETTAYFFMKPKLGEKEVSPNAFFSIWHEFSSDFKDFWKKENK----------LLLQ 1685
K + YF K VS FF + F + F + ++ NK L
Sbjct: 970 KLYENLGEYFI----FDSKTVSIEEFFGDLNNFRTLFLEAVRENNKRREMEEKTRRAKLA 1025
Query: 1686 ERVKEAEEVCRQKKGKSLYKIKPRHD 1711
+ E E++ RQKK K L I D
Sbjct: 1026 KEKAEQEKLERQKKKKQLIDINKEGD 1051
Score = 90.5 bits (223), Expect = 1e-17
Identities = 55/107 (51%), Positives = 57/107 (53%), Gaps = 37/107 (34%)
Query: 918 AGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPP 977
+GIP PP P PLPG G PPPPP P PLPG G PLP PP
Sbjct: 546 SGIPGPPAAP--------PLPGVGPPPPPPAP--------PLPG-GAPLP--------PP 580
Query: 978 PPPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1023
PPPLPG GIPP PPPPPL G PPPPPL G+PPPP
Sbjct: 581 PPPLPGMMGIPP---------PPPPPLLFGGPPPPPPL--GGVPPPP 616
Score = 89.4 bits (220), Expect = 3e-17
Identities = 47/79 (59%), Positives = 50/79 (63%), Gaps = 14/79 (17%)
Query: 1094 AGIPPPP---PLPGVGIPPPPPLPGAGIPPPPPLPGAG--IPPPPPLPG-AGIPPPPPLP 1147
+GIP PP PLPGVG PPPPP P PLPG PPPPPLPG GIPPPPP P
Sbjct: 546 SGIPGPPAAPPLPGVGPPPPPPAP--------PLPGGAPLPPPPPPLPGMMGIPPPPPPP 597
Query: 1148 RVGIPPPPPLPGAGIPPPP 1166
+ PPPP P G+PPPP
Sbjct: 598 LLFGGPPPPPPLGGVPPPP 616
Score = 88.6 bits (218), Expect = 5e-17
Identities = 50/88 (56%), Positives = 53/88 (60%), Gaps = 21/88 (23%)
Query: 973 AGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPLPGA 1028
+GIP PP PLPG G PPPPP P +P PLP PPPPPLPG GIPP
Sbjct: 546 SGIPGPPAAPPLPGVGPPPPPPAPP--LPGGAPLP----PPPPPLPGMMGIPP------- 592
Query: 1029 GIPPPPPLPGAGIPPPPPLPGAGIPPPP 1056
PPPPPL G PPPPPL G+PPPP
Sbjct: 593 --PPPPPLLFGGPPPPPPL--GGVPPPP 616
Score = 88.6 bits (218), Expect = 5e-17
Identities = 53/99 (53%), Positives = 55/99 (55%), Gaps = 32/99 (32%)
Query: 995 AGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-A 1050
+GIP PP PLPG G PPPPP P PLPG PLP PPPPPLPG
Sbjct: 546 SGIPGPPAAPPLPGVGPPPPPPAP--------PLPGGA-----PLP----PPPPPLPGMM 588
Query: 1051 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1089
GIPPPP PPPL G PPPPPL G+PPPP
Sbjct: 589 GIPPPP---------PPPLLFGGPPPPPPL--GGVPPPP 616
Score = 88.6 bits (218), Expect = 5e-17
Identities = 50/88 (56%), Positives = 53/88 (60%), Gaps = 21/88 (23%)
Query: 1050 AGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPLPGV 1105
+GIP PP PLPG G PPPPP P +P PLP PPPPPLPG GIPPPP
Sbjct: 546 SGIPGPPAAPPLPGVGPPPPPPAPP--LPGGAPLP----PPPPPLPGMMGIPPPP----- 594
Query: 1106 GIPPPPPLPGAGIPPPPPLPGAGIPPPP 1133
PPPL G PPPPPL G+PPPP
Sbjct: 595 ----PPPLLFGGPPPPPPL--GGVPPPP 616
Score = 88.2 bits (217), Expect = 6e-17
Identities = 48/84 (57%), Positives = 50/84 (59%), Gaps = 18/84 (21%)
Query: 963 GIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPLPGAGIPP 1021
G P PPLPG G PPPPP P +P PLP PPPPPLPG GIPP PP
Sbjct: 550 GPPAAPPLPGVGPPPPPPAPP--LPGGAPLP----PPPPPLPGMMGIPP---------PP 594
Query: 1022 PPPLPGAGIPPPPPLPGAGIPPPP 1045
PPPL G PPPPPL G+PPPP
Sbjct: 595 PPPLLFGGPPPPPPL--GGVPPPP 616
Score = 87.8 bits (216), Expect = 8e-17
Identities = 50/88 (56%), Positives = 53/88 (60%), Gaps = 21/88 (23%)
Query: 1072 AGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPG-AGIPPPPPLPGA 1127
+GIP PP PLPG G PPPPP P +P PLP PPPPPLPG GIPP
Sbjct: 546 SGIPGPPAAPPLPGVGPPPPPPAPP--LPGGAPLP----PPPPPLPGMMGIPP------- 592
Query: 1128 GIPPPPPLPGAGIPPPPPLPRVGIPPPP 1155
PPPPPL G PPPPPL G+PPPP
Sbjct: 593 --PPPPPLLFGGPPPPPPLG--GVPPPP 616
Score = 87.4 bits (215), Expect = 1e-16
Identities = 53/103 (51%), Positives = 57/103 (55%), Gaps = 24/103 (23%)
Query: 866 SSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPG-AGIPPPP 924
SSS +PG PP PPLPG+ P P PPL G LPPPPPPLPG GIPPPP
Sbjct: 544 SSSGIPG----PPAAPPLPGVGPPPPPPA-----PPLPGGAPLPPPPPPLPGMMGIPPPP 594
Query: 925 PLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLP 967
P PPL G PPPPPL G +PPP PG + LP
Sbjct: 595 P---------PPLLFGGPPPPPPLGG--VPPP---PGISLNLP 623
Score = 87.4 bits (215), Expect = 1e-16
Identities = 53/99 (53%), Positives = 55/99 (55%), Gaps = 32/99 (32%)
Query: 1028 AGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-A 1083
+GIP PP PLPG G PPPPP P PLPG PLP PPPPPLPG
Sbjct: 546 SGIPGPPAAPPLPGVGPPPPPPAP--------PLPGGA-----PLP----PPPPPLPGMM 588
Query: 1084 GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPP 1122
GIPPPP PPPL G PPPPPL G+PPPP
Sbjct: 589 GIPPPP---------PPPLLFGGPPPPPPL--GGVPPPP 616
Score = 87.4 bits (215), Expect = 1e-16
Identities = 48/85 (56%), Positives = 49/85 (57%), Gaps = 22/85 (25%)
Query: 909 PPPPPPLPGAGIPPPPPLPGAGILPLP---PLPGAGIPPPPPLPGAAIPPPPPLPGAGIP 965
PP PPLPG G PPPPP P PLP PLP PPPPPLPG PPPP
Sbjct: 551 PPAAPPLPGVGPPPPPPAP-----PLPGGAPLP----PPPPPLPGMMGIPPPP------- 594
Query: 966 LPPPLPGAGIPPPPPLPGAGIPPPP 990
PPPL G PPPPPL G+PPPP
Sbjct: 595 -PPPLLFGGPPPPPPL--GGVPPPP 616
Score = 53.5 bits (127), Expect = 2e-06
Identities = 43/143 (30%), Positives = 48/143 (33%), Gaps = 75/143 (52%)
Query: 803 PTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLP 862
P + PPPPP+ PPLP
Sbjct: 556 PLPGVGPPPPPPA-------------------------------------------PPLP 572
Query: 863 CTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPP 922
G +PPPPPPLPGM IP PPPPPPL G PP
Sbjct: 573 ---------GGAPLPPPPPPLPGM-------MGIP-----------PPPPPPLLFGGPPP 605
Query: 923 PPPLPGAGILPLPPLPGAGIPPP 945
PPPL G +PP PG + P
Sbjct: 606 PPPLGG-----VPPPPGISLNLP 623
>gi|21071077 dishevelled-associated activator of morphogenesis 1 [Homo
sapiens]
Length = 1078
Score = 177 bits (449), Expect = 8e-44
Identities = 155/567 (27%), Positives = 258/567 (45%), Gaps = 87/567 (15%)
Query: 1171 AGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGT 1230
A IP P G P P +PG +PPPPP PPLPG +PP P PPLPP G
Sbjct: 525 ASIPGGPSPGAPGGPFPSSVPGSLLPPPPP---------PPLPGGMLPPPP-PPLPPGGP 574
Query: 1231 GIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPC 1290
PPPP GPP L G + PP P GL + +K +P
Sbjct: 575 --PPPP-----GPPPL--------------GAIMPP-PGAPMGLALK-----KKSIPQPT 607
Query: 1291 RPMKPLYWTRIQLHSKRDSSTSLIWEKIEEPSI----DCHEFEELFS-----------KT 1335
+K W+++ + +W +I++ + D + E FS
Sbjct: 608 NALKSFNWSKLP----ENKLEGTVWTEIDDTKVFKILDLEDLERTFSAYQRQQDFFVNSN 663
Query: 1336 AVKERKKPISDTISKTKAKQVVKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSV-V 1394
+ ++ I DT+S + + ++ +R+Q IL+S L L +I+ A++ +D +
Sbjct: 664 SKQKEADAIDDTLSSKLKVKELSVIDGRRAQNCNILLSRLKLSNDEIKRAILTMDEQEDL 723
Query: 1395 DLETLQALYENRAQSDELEKIEKHGRSSKDKENAKSLDKPEQFLYELSLIPNFSERVFCI 1454
+ L+ L + + +++ +E+H K + K ++FL+E+S I ++ +R+ +
Sbjct: 724 PKDMLEQLLKFVPEKSDIDLLEEH------KHELDRMAKADRFLFEMSRINHYQQRLQSL 777
Query: 1455 LFQSTFSESICSIRRKLELLQKLCETLKNGPGVMQVLGLVLAFGNYMNGGNKTRGQADGF 1514
F+ F+E + ++ K+E ++ E + + Q+L +VLAFGNYMN G RG A GF
Sbjct: 778 YFKKKFAERVAEVKPKVEAIRSGSEEVFRSGALKQLLEVVLAFGNYMNKGQ--RGNAYGF 835
Query: 1515 GLDILPKLKDVKSS-DNSRSLLSYIVSYYLRNFDEDAGKEQCLFPLPEPQDLFQASQMKF 1573
+ L K+ D KSS D + +LL Y+++ + + E +D+ QA+++
Sbjct: 836 KISSLNKIADTKSSIDKNITLLHYLITIVENKYPSVLNLNE------ELRDIPQAAKVNM 889
Query: 1574 EDFQKDLRKLKKDLKACEVEAGKVYQVSS-KEHMQPFKENMEQFIIQAKIDQEAEENSLT 1632
+ K++ L+ LKA E E YQ S + F + QFI A E+ L
Sbjct: 890 TELDKEISTLRSGLKAVETEL--EYQKSQPPQPGDKFVSVVSQFITVASFSFSDVEDLLA 947
Query: 1633 ETHKCFLETTAYFFMKPKLGEK--EVSPNAFFSIWHEFSSDFKDFWKKENKLLLQERVKE 1690
E F + +F GE+ ++ P+ FF I+ +F + K+EN+ + R K+
Sbjct: 948 EAKDLFTKAVKHF------GEEAGKIQPDEFFGIFDQFLQAVSEA-KQENENM---RKKK 997
Query: 1691 AEEVCRQKKGKSLYKIKPRHDSGIKAK 1717
EE R + L + + R KAK
Sbjct: 998 EEEERRARMEAQLKEQRERERKMRKAK 1024
Score = 71.6 bits (174), Expect = 6e-12
Identities = 43/92 (46%), Positives = 47/92 (51%), Gaps = 15/92 (16%)
Query: 955 PPPPLPGA-GIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI-PPPPPLPGAGIPPPP 1012
P P PGA G P P +PG+ +PP PPPPPLPG + PPPPPLP G PPPP
Sbjct: 528 PGGPSPGAPGGPFPSSVPGSLLPP---------PPPPPLPGGMLPPPPPPLPPGGPPPPP 578
Query: 1013 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1044
P G PPP G P L IP P
Sbjct: 579 GPPPLGAIMPPP----GAPMGLALKKKSIPQP 606
Score = 71.2 bits (173), Expect = 8e-12
Identities = 43/93 (46%), Positives = 48/93 (51%), Gaps = 15/93 (16%)
Query: 932 LPLPPLPGA-GIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGI-PPPPPLPGAGIPPP 989
+P P PGA G P P +PG+ +PPPPP PPLPG + PPPPPLP G PPP
Sbjct: 527 IPGGPSPGAPGGPFPSSVPGSLLPPPPP---------PPLPGGMLPPPPPPLPPGGPPPP 577
Query: 990 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1022
P P G PPP G P L IP P
Sbjct: 578 PGPPPLGAIMPPP----GAPMGLALKKKSIPQP 606
Score = 70.9 bits (172), Expect = 1e-11
Identities = 43/92 (46%), Positives = 48/92 (52%), Gaps = 15/92 (16%)
Query: 1120 PPPPLPGA-GIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGI-PPPPPLPGAGIPPPP 1177
P P PGA G P P +PG+ +PPPPP PPLPG + PPPPPLP G PPPP
Sbjct: 528 PGGPSPGAPGGPFPSSVPGSLLPPPPP---------PPLPGGMLPPPPPPLPPGGPPPPP 578
Query: 1178 PLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPP 1209
P +G PPP G P L IP P
Sbjct: 579 GPPPLGAIMPPP----GAPMGLALKKKSIPQP 606
Score = 70.5 bits (171), Expect = 1e-11
Identities = 46/102 (45%), Positives = 52/102 (50%), Gaps = 24/102 (23%)
Query: 1054 PPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP 1112
P P PGA G P P +PG+ +PP PPPPPLPG +PPPPP G PPPP
Sbjct: 528 PGGPSPGAPGGPFPSSVPGSLLPP---------PPPPPLPGGMLPPPPPPLPPGGPPPP- 577
Query: 1113 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPP 1154
P PPPL GA +PPP G P L + IP P
Sbjct: 578 ------PGPPPL-GAIMPPP------GAPMGLALKKKSIPQP 606
Score = 70.1 bits (170), Expect = 2e-11
Identities = 43/92 (46%), Positives = 47/92 (51%), Gaps = 15/92 (16%)
Query: 988 PPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI-PPPPPLPGAGIPPPP 1045
P P PGA G P P +PG+ +PP PPPPPLPG + PPPPPLP G PPPP
Sbjct: 528 PGGPSPGAPGGPFPSSVPGSLLPP---------PPPPPLPGGMLPPPPPPLPPGGPPPPP 578
Query: 1046 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1077
P G PPP G P L IP P
Sbjct: 579 GPPPLGAIMPPP----GAPMGLALKKKSIPQP 606
Score = 70.1 bits (170), Expect = 2e-11
Identities = 43/92 (46%), Positives = 47/92 (51%), Gaps = 15/92 (16%)
Query: 999 PPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI-PPPPPLPGAGIPPPP 1056
P P PGA G P P +PG+ +PPPPP PPLPG + PPPPPLP G PPPP
Sbjct: 528 PGGPSPGAPGGPFPSSVPGSLLPPPPP---------PPLPGGMLPPPPPPLPPGGPPPPP 578
Query: 1057 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1088
P G PPP G P L IP P
Sbjct: 579 GPPPLGAIMPPP----GAPMGLALKKKSIPQP 606
Score = 70.1 bits (170), Expect = 2e-11
Identities = 43/92 (46%), Positives = 47/92 (51%), Gaps = 15/92 (16%)
Query: 1032 PPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI-PPPPPLPGAGIPPPP 1089
P P PGA G P P +PG+ +PPPPP PPLPG + PPPPPLP G PPPP
Sbjct: 528 PGGPSPGAPGGPFPSSVPGSLLPPPPP---------PPLPGGMLPPPPPPLPPGGPPPPP 578
Query: 1090 PLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPP 1121
P G PPP G P L IP P
Sbjct: 579 GPPPLGAIMPPP----GAPMGLALKKKSIPQP 606
Score = 70.1 bits (170), Expect = 2e-11
Identities = 43/92 (46%), Positives = 47/92 (51%), Gaps = 15/92 (16%)
Query: 1076 PPPPLPGA-GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGI-PPPPPLPGAGIPPPP 1133
P P PGA G P P +PG+ +PPPPP PPLPG + PPPPPLP G PPPP
Sbjct: 528 PGGPSPGAPGGPFPSSVPGSLLPPPPP---------PPLPGGMLPPPPPPLPPGGPPPPP 578
Query: 1134 PLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPP 1165
P G PPP G P L IP P
Sbjct: 579 GPPPLGAIMPPP----GAPMGLALKKKSIPQP 606
Score = 69.7 bits (169), Expect = 2e-11
Identities = 43/92 (46%), Positives = 47/92 (51%), Gaps = 15/92 (16%)
Query: 1021 PPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI-PPPPPLPGAGIPPPP 1078
P P PGA G P P +PG+ +PP PPPPPLPG + PPPPPLP G PPPP
Sbjct: 528 PGGPSPGAPGGPFPSSVPGSLLPP---------PPPPPLPGGMLPPPPPPLPPGGPPPPP 578
Query: 1079 PLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPP 1110
P G PPP G P L IP P
Sbjct: 579 GPPPLGAIMPPP----GAPMGLALKKKSIPQP 606
Score = 69.3 bits (168), Expect = 3e-11
Identities = 42/97 (43%), Positives = 47/97 (48%), Gaps = 18/97 (18%)
Query: 883 LPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGI 942
+PG P P P P G+ + PPPPPPLPG +PPPPP PLP G
Sbjct: 527 IPGGPSPGAPGGPFPSSVP--GSLLPPPPPPPLPGGMLPPPPP----------PLPPGGP 574
Query: 943 PPPP-PLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPP 978
PPPP P P AI PPP G P+ L IP P
Sbjct: 575 PPPPGPPPLGAIMPPP-----GAPMGLALKKKSIPQP 606
Score = 68.9 bits (167), Expect = 4e-11
Identities = 42/89 (47%), Positives = 46/89 (51%), Gaps = 15/89 (16%)
Query: 969 PLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI-PPPPPLPGAGIPPPPPLP 1026
P PGA G P P +PG+ +PPPPP PPLPG + PPPPPLP G PPPP P
Sbjct: 531 PSPGAPGGPFPSSVPGSLLPPPPP---------PPLPGGMLPPPPPPLPPGGPPPPPGPP 581
Query: 1027 GAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1055
G PPP G P L IP P
Sbjct: 582 PLGAIMPPP----GAPMGLALKKKSIPQP 606
Score = 67.8 bits (164), Expect = 9e-11
Identities = 45/105 (42%), Positives = 50/105 (47%), Gaps = 23/105 (21%)
Query: 1094 AGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPP 1153
A IP P G P P +PG+ +PP PPPPPLPG +PPPPP G PP
Sbjct: 525 ASIPGGPSPGAPGGPFPSSVPGSLLPP---------PPPPPLPGGMLPPPPPPLPPGGPP 575
Query: 1154 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPP 1198
PP P PPPL GA +PPP G P L IP P
Sbjct: 576 PP-------PGPPPL-GAIMPPP------GAPMGLALKKKSIPQP 606
Score = 65.1 bits (157), Expect = 6e-10
Identities = 40/98 (40%), Positives = 44/98 (44%), Gaps = 24/98 (24%)
Query: 859 PPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGA 918
P P SS+PG + PPPPPPLPG MLPPPPPPLP
Sbjct: 533 PGAPGGPFPSSVPGSLLPPPPPPPLPG--------------------GMLPPPPPPLPPG 572
Query: 919 GIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPP 956
G PPPP P G + PP G P L +IP P
Sbjct: 573 GPPPPPGPPPLGAIMPPP----GAPMGLALKKKSIPQP 606
Score = 46.2 bits (108), Expect = 3e-04
Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 15/61 (24%)
Query: 855 IPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPP 914
+P PPP P +PG GM+PPPPPPLP P P PPPL ++PPP P
Sbjct: 549 LPPPPPPP-------LPG-GMLPPPPPPLPPGGPPPPPG-----PPPLGA--IMPPPGAP 593
Query: 915 L 915
+
Sbjct: 594 M 594
Score = 35.0 bits (79), Expect = 0.63
Identities = 53/231 (22%), Positives = 80/231 (34%), Gaps = 76/231 (32%)
Query: 676 IQQLEQTIEDLRTKIAELERQYPALDTEVASGHQGLENGVTASGDVCLEALRLEEKEVRH 735
++Q ++ E +R + EL+++ + E + Q E + + +LE++ H
Sbjct: 445 VKQWKEQAEKMRKEHNELQQKLEKKERECDAKTQEKEEMMQTLNKM---KEKLEKETTEH 501
Query: 736 HRILEAKSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRIS 795
++ + + T+ E + +PG P PGA GP F S +
Sbjct: 502 KQVKQQVADLTAQLHE--LSRRAVCASIPGGPS--PGAPGGP---FPSSVP--------- 545
Query: 796 VQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNI 855
S+ PPPPP L PG P
Sbjct: 546 ---------GSLLPPPPPPPL--------PGGMLP------------------------- 563
Query: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVP-------TLPSTAIPQP 899
P PPPLP PG PP PPPL + P L +IPQP
Sbjct: 564 PPPPPLP--------PGGPPPPPGPPPLGAIMPPPGAPMGLALKKKSIPQP 606
>gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]
Length = 849
Score = 177 bits (448), Expect = 1e-43
Identities = 147/541 (27%), Positives = 245/541 (45%), Gaps = 67/541 (12%)
Query: 1195 IPPPPPLPG----AGIPPPPPLP-GMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQV 1249
IP PP G + +PPPPPLP G G+PP P PP PPP G+ +P SGP
Sbjct: 297 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPPPPPPPPLPGMR----MPFSGP------ 346
Query: 1250 GSSTLPTPQVCGFL----PPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHS 1305
+P P GFL PPLP FGL K+ +P M+ L W +I+ H
Sbjct: 347 ----VPPPPPLGFLGGQNSPPLPILPFGL-------KPKKEFKPEISMRRLNWLKIRPH- 394
Query: 1306 KRDSSTSLIWEKIEEPSID-----CHEFEELFSKTAVKERKKPISDTISKTKAKQVVKLL 1360
+ + + W K+ E + C + + ++ I + S K + +K L
Sbjct: 395 --EMTENCFWIKVNENKYENVDLLCKLENTFCCQQKERREEEDIEEKKSIKKKIKELKFL 452
Query: 1361 SNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIEKHGR 1420
+K +Q + I +SS + ++I+ ++ +D + + +Q L ++ ++L +
Sbjct: 453 DSKIAQNLSIFLSSFRVPYEEIRMMILEVDETRLAESMIQNLIKHLPDQEQLNSL----- 507
Query: 1421 SSKDKENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQKLCET 1480
S+ K +L +PEQF+ +S + R+ ILF+ F E + +I+ + + CE
Sbjct: 508 -SQFKSEYSNLCEPEQFVVVMSNVKRLRPRLSAILFKLQFEEQVNNIKPDIMAVSTACEE 566
Query: 1481 LKNGPGVMQVLGLVLAFGNYMNGGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLSYIVS 1540
+K ++L LVL GNYMN G++ Q GF L L KLKD KS+D +LL ++V
Sbjct: 567 IKKSKSFSKLLELVLLMGNYMNAGSR-NAQTFGFNLSSLCKLKDTKSADQKTTLLHFLVE 625
Query: 1541 YYLRNFDEDAGKEQCLFPLPEPQDLFQASQMKFEDFQKDLRKLKKDLKACEVEAGKVYQV 1600
+ + L PL +AS++ E +K+LR++ + L+ E E + +
Sbjct: 626 ICEEKYPDILNFVDDLEPLD------KASKVSVETLEKNLRQMGRQLQQLEKEL-ETFPP 678
Query: 1601 SSKEHMQPFKENMEQFIIQAKIDQEAEENSLTETHKCFLETTAYFFMKPKLGEKEVSPNA 1660
H F M +F+I AK E K + Y+ + K+VS
Sbjct: 679 PEDLH-DKFVTKMSRFVISAKEQYETLSKLHENMEKLYQSIIGYY----AIDVKKVSVED 733
Query: 1661 FFSIWHEFSSDF----------KDFWKKENKLLLQERVKEAEEVCRQKKGKSLYKIKPRH 1710
F + + F + F ++ +KE ++ + + + E E + RQ+K K L ++K
Sbjct: 734 FLTDLNNFRTTFMQAIKENIKKREAEEKEKRVRIAKELAERERLERQQKKKRLLEMKTEG 793
Query: 1711 D 1711
D
Sbjct: 794 D 794
Score = 75.5 bits (184), Expect = 4e-13
Identities = 41/79 (51%), Positives = 46/79 (58%), Gaps = 15/79 (18%)
Query: 964 IPLPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1018
IPLPP G + +PPPPPLP G G+PPPPP PPPPPLPG +P P
Sbjct: 297 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-----PPPPPPLPGMRMPFSGP----- 346
Query: 1019 IPPPPPLPGAGIPPPPPLP 1037
+PPPPPL G PPLP
Sbjct: 347 VPPPPPLGFLGGQNSPPLP 365
Score = 73.6 bits (179), Expect = 2e-12
Identities = 40/79 (50%), Positives = 46/79 (58%), Gaps = 15/79 (18%)
Query: 1063 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAG 1117
IP PP G + +PPPPPLP G G+PPPPP PPPPPLPG+ +P P
Sbjct: 297 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-----PPPPPPLPGMRMPFSGP----- 346
Query: 1118 IPPPPPLPGAGIPPPPPLP 1136
+PPPPPL G PPLP
Sbjct: 347 VPPPPPLGFLGGQNSPPLP 365
Score = 72.8 bits (177), Expect = 3e-12
Identities = 40/79 (50%), Positives = 45/79 (56%), Gaps = 15/79 (18%)
Query: 997 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1051
IP PP G + +PPPPPLP G G+PPPPP PPPPPLPG +P P
Sbjct: 297 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-----PPPPPPLPGMRMPFSGP----- 346
Query: 1052 IPPPPPLPGAGIPPPPPLP 1070
+PPPPPL G PPLP
Sbjct: 347 VPPPPPLGFLGGQNSPPLP 365
Score = 72.8 bits (177), Expect = 3e-12
Identities = 40/79 (50%), Positives = 45/79 (56%), Gaps = 15/79 (18%)
Query: 1030 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1084
IP PP G + +PPPPPLP G G+PPPPP PPPPPLPG +P P
Sbjct: 297 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-----PPPPPPLPGMRMPFSGP----- 346
Query: 1085 IPPPPPLPGAGIPPPPPLP 1103
+PPPPPL G PPLP
Sbjct: 347 VPPPPPLGFLGGQNSPPLP 365
Score = 72.8 bits (177), Expect = 3e-12
Identities = 40/79 (50%), Positives = 45/79 (56%), Gaps = 15/79 (18%)
Query: 1074 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAG 1128
IP PP G + +PPPPPLP G G+PPPPP PPPPPLPG +P P
Sbjct: 297 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-----PPPPPPLPGMRMPFSGP----- 346
Query: 1129 IPPPPPLPGAGIPPPPPLP 1147
+PPPPPL G PPLP
Sbjct: 347 VPPPPPLGFLGGQNSPPLP 365
Score = 71.6 bits (174), Expect = 6e-12
Identities = 40/79 (50%), Positives = 44/79 (55%), Gaps = 15/79 (18%)
Query: 1096 IPPPPPLPG----VGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVG 1150
IP PP G +PPPPPLP G G+PPPPP PPPPPLPG +P P
Sbjct: 297 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-----PPPPPPLPGMRMPFSGP----- 346
Query: 1151 IPPPPPLPGAGIPPPPPLP 1169
+PPPPPL G PPLP
Sbjct: 347 VPPPPPLGFLGGQNSPPLP 365
Score = 70.5 bits (171), Expect = 1e-11
Identities = 40/79 (50%), Positives = 45/79 (56%), Gaps = 15/79 (18%)
Query: 942 IPPPPPLPG----AAIPPPPPLP-GAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 996
IP PP G +A+PPPPPLP G G+P PPP PPPPPLPG +P P
Sbjct: 297 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-----PPPPPPLPGMRMPFSGP----- 346
Query: 997 IPPPPPLPGAGIPPPPPLP 1015
+PPPPPL G PPLP
Sbjct: 347 VPPPPPLGFLGGQNSPPLP 365
Score = 67.4 bits (163), Expect = 1e-10
Identities = 38/79 (48%), Positives = 42/79 (53%), Gaps = 13/79 (16%)
Query: 896 IPQPPPLQGT---EMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAA 952
IP PP +G LPPPPP G G+PPPPP P P PPLPG +P P
Sbjct: 297 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPPPP-----PPPPLPGMRMPFSGP----- 346
Query: 953 IPPPPPLPGAGIPLPPPLP 971
+PPPPPL G PPLP
Sbjct: 347 VPPPPPLGFLGGQNSPPLP 365
Score = 66.2 bits (160), Expect = 3e-10
Identities = 38/79 (48%), Positives = 44/79 (55%), Gaps = 15/79 (18%)
Query: 1041 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1095
IP PP G + +PPPPPLP G G+PPPPP PPPP P G+ P P
Sbjct: 297 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-------PPPPPPLPGMRMPFSGP--- 346
Query: 1096 IPPPPPLPGVGIPPPPPLP 1114
+PPPPPL +G PPLP
Sbjct: 347 VPPPPPLGFLGGQNSPPLP 365
Score = 65.9 bits (159), Expect = 3e-10
Identities = 38/79 (48%), Positives = 43/79 (54%), Gaps = 15/79 (18%)
Query: 1107 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAG 1161
IP PP G + +PPPPPLP G G+PPPPP PPPP P G+ P P
Sbjct: 297 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-------PPPPPPLPGMRMPFSGP--- 346
Query: 1162 IPPPPPLPGAGIPPPPPLP 1180
+PPPPPL G PPLP
Sbjct: 347 VPPPPPLGFLGGQNSPPLP 365
Score = 65.5 bits (158), Expect = 4e-10
Identities = 38/79 (48%), Positives = 43/79 (54%), Gaps = 15/79 (18%)
Query: 975 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1029
IP PP G + +PPPPPLP G G+PPPPP PPPP P G+ P P
Sbjct: 297 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-------PPPPPPLPGMRMPFSGP--- 346
Query: 1030 IPPPPPLPGAGIPPPPPLP 1048
+PPPPPL G PPLP
Sbjct: 347 VPPPPPLGFLGGQNSPPLP 365
Score = 65.5 bits (158), Expect = 4e-10
Identities = 38/79 (48%), Positives = 43/79 (54%), Gaps = 15/79 (18%)
Query: 986 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1040
IP PP G + +PPPPPLP G G+PPPPP PPPP P G+ P P
Sbjct: 297 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-------PPPPPPLPGMRMPFSGP--- 346
Query: 1041 IPPPPPLPGAGIPPPPPLP 1059
+PPPPPL G PPLP
Sbjct: 347 VPPPPPLGFLGGQNSPPLP 365
Score = 65.5 bits (158), Expect = 4e-10
Identities = 38/79 (48%), Positives = 43/79 (54%), Gaps = 15/79 (18%)
Query: 1008 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1062
IP PP G + +PPPPPLP G G+PPPPP PPPP P G+ P P
Sbjct: 297 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-------PPPPPPLPGMRMPFSGP--- 346
Query: 1063 IPPPPPLPGAGIPPPPPLP 1081
+PPPPPL G PPLP
Sbjct: 347 VPPPPPLGFLGGQNSPPLP 365
Score = 65.5 bits (158), Expect = 4e-10
Identities = 38/79 (48%), Positives = 43/79 (54%), Gaps = 15/79 (18%)
Query: 1019 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1073
IP PP G + +PPPPPLP G G+PPPPP PPPP P G+ P P
Sbjct: 297 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-------PPPPPPLPGMRMPFSGP--- 346
Query: 1074 IPPPPPLPGAGIPPPPPLP 1092
+PPPPPL G PPLP
Sbjct: 347 VPPPPPLGFLGGQNSPPLP 365
Score = 65.5 bits (158), Expect = 4e-10
Identities = 38/79 (48%), Positives = 43/79 (54%), Gaps = 15/79 (18%)
Query: 1052 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG 1106
IP PP G + +PPPPPLP G G+PPPPP PPPP P G+ P P
Sbjct: 297 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-------PPPPPPLPGMRMPFSGP--- 346
Query: 1107 IPPPPPLPGAGIPPPPPLP 1125
+PPPPPL G PPLP
Sbjct: 347 VPPPPPLGFLGGQNSPPLP 365
Score = 65.1 bits (157), Expect = 6e-10
Identities = 38/79 (48%), Positives = 44/79 (55%), Gaps = 15/79 (18%)
Query: 1085 IPPPPPLPG----AGIPPPPPLP-GVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1139
IP PP G + +PPPPPLP G G+PPPPP PPPP P G+ P P
Sbjct: 297 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-------PPPPPPLPGMRMPFSGP--- 346
Query: 1140 IPPPPPLPRVGIPPPPPLP 1158
+PPPPPL +G PPLP
Sbjct: 347 VPPPPPLGFLGGQNSPPLP 365
Score = 63.9 bits (154), Expect = 1e-09
Identities = 38/89 (42%), Positives = 44/89 (49%), Gaps = 23/89 (25%)
Query: 908 LPPPPPPLPGAG---IPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGI 964
+P PP G G +PPPPPLP G G+PPPPP PPPP P G+
Sbjct: 297 IPLPPSKEGGTGHSALPPPPPLPSGG----------GVPPPPP-------PPPPPPLPGM 339
Query: 965 PLPPPLPGAGIPPPPPLPGAGIPPPPPLP 993
+P P +PPPPPL G PPLP
Sbjct: 340 RMPFSGP---VPPPPPLGFLGGQNSPPLP 365
Score = 62.4 bits (150), Expect = 4e-09
Identities = 41/98 (41%), Positives = 44/98 (44%), Gaps = 29/98 (29%)
Query: 848 AFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPS-TAIPQPPPLQGTE 906
A CNIP PP S G +PPPPP LPS +P PPP
Sbjct: 290 ALPADCNIPLPP------SKEGGTGHSALPPPPP---------LPSGGGVPPPPP----- 329
Query: 907 MLPPPPPPLPG------AGIPPPPPLPGAGILPLPPLP 938
PPPPPPLPG +PPPPPL G PPLP
Sbjct: 330 --PPPPPPLPGMRMPFSGPVPPPPPLGFLGGQNSPPLP 365
Score = 61.2 bits (147), Expect = 8e-09
Identities = 38/85 (44%), Positives = 43/85 (50%), Gaps = 16/85 (18%)
Query: 926 LPGAGILPLPPLPGAG-----IPPPPPLP-GAAIPPPPPLPGAGIPLPPPLPGAGIPPPP 979
LP +PLPP G +PPPPPLP G +PPPPP P PP P G+ P
Sbjct: 291 LPADCNIPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPPPP-------PPPPLPGMRMPF 343
Query: 980 PLPGAGIPPPPPLPGAGIPPPPPLP 1004
P +PPPPPL G PPLP
Sbjct: 344 SGP---VPPPPPLGFLGGQNSPPLP 365
Score = 51.2 bits (121), Expect = 8e-06
Identities = 29/68 (42%), Positives = 34/68 (50%), Gaps = 6/68 (8%)
Query: 855 IPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPP 914
+P PPPLP P PPPPPPLPGM +P S +P PPPL PP P
Sbjct: 312 LPPPPPLPSGGGVPPPPP----PPPPPPLPGMRMPF--SGPVPPPPPLGFLGGQNSPPLP 365
Query: 915 LPGAGIPP 922
+ G+ P
Sbjct: 366 ILPFGLKP 373
>gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]
Length = 1193
Score = 177 bits (448), Expect = 1e-43
Identities = 147/541 (27%), Positives = 245/541 (45%), Gaps = 67/541 (12%)
Query: 1195 IPPPPPLPG----AGIPPPPPLP-GMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQV 1249
IP PP G + +PPPPPLP G G+PP P PP PPP G+ +P SGP
Sbjct: 560 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPPPPPPPPLPGMR----MPFSGP------ 609
Query: 1250 GSSTLPTPQVCGFL----PPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHS 1305
+P P GFL PPLP FGL K+ +P M+ L W +I+ H
Sbjct: 610 ----VPPPPPLGFLGGQNSPPLPILPFGL-------KPKKEFKPEISMRRLNWLKIRPH- 657
Query: 1306 KRDSSTSLIWEKIEEPSID-----CHEFEELFSKTAVKERKKPISDTISKTKAKQVVKLL 1360
+ + + W K+ E + C + + ++ I + S K + +K L
Sbjct: 658 --EMTENCFWIKVNENKYENVDLLCKLENTFCCQQKERREEEDIEEKKSIKKKIKELKFL 715
Query: 1361 SNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIEKHGR 1420
+K +Q + I +SS + ++I+ ++ +D + + +Q L ++ ++L +
Sbjct: 716 DSKIAQNLSIFLSSFRVPYEEIRMMILEVDETRLAESMIQNLIKHLPDQEQLNSL----- 770
Query: 1421 SSKDKENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQKLCET 1480
S+ K +L +PEQF+ +S + R+ ILF+ F E + +I+ + + CE
Sbjct: 771 -SQFKSEYSNLCEPEQFVVVMSNVKRLRPRLSAILFKLQFEEQVNNIKPDIMAVSTACEE 829
Query: 1481 LKNGPGVMQVLGLVLAFGNYMNGGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLSYIVS 1540
+K ++L LVL GNYMN G++ Q GF L L KLKD KS+D +LL ++V
Sbjct: 830 IKKSKSFSKLLELVLLMGNYMNAGSR-NAQTFGFNLSSLCKLKDTKSADQKTTLLHFLVE 888
Query: 1541 YYLRNFDEDAGKEQCLFPLPEPQDLFQASQMKFEDFQKDLRKLKKDLKACEVEAGKVYQV 1600
+ + L PL +AS++ E +K+LR++ + L+ E E + +
Sbjct: 889 ICEEKYPDILNFVDDLEPLD------KASKVSVETLEKNLRQMGRQLQQLEKEL-ETFPP 941
Query: 1601 SSKEHMQPFKENMEQFIIQAKIDQEAEENSLTETHKCFLETTAYFFMKPKLGEKEVSPNA 1660
H F M +F+I AK E K + Y+ + K+VS
Sbjct: 942 PEDLH-DKFVTKMSRFVISAKEQYETLSKLHENMEKLYQSIIGYY----AIDVKKVSVED 996
Query: 1661 FFSIWHEFSSDF----------KDFWKKENKLLLQERVKEAEEVCRQKKGKSLYKIKPRH 1710
F + + F + F ++ +KE ++ + + + E E + RQ+K K L ++K
Sbjct: 997 FLTDLNNFRTTFMQAIKENIKKREAEEKEKRVRIAKELAERERLERQQKKKRLLEMKTEG 1056
Query: 1711 D 1711
D
Sbjct: 1057 D 1057
Score = 75.5 bits (184), Expect = 4e-13
Identities = 41/79 (51%), Positives = 46/79 (58%), Gaps = 15/79 (18%)
Query: 964 IPLPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1018
IPLPP G + +PPPPPLP G G+PPPPP PPPPPLPG +P P
Sbjct: 560 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-----PPPPPPLPGMRMPFSGP----- 609
Query: 1019 IPPPPPLPGAGIPPPPPLP 1037
+PPPPPL G PPLP
Sbjct: 610 VPPPPPLGFLGGQNSPPLP 628
Score = 73.6 bits (179), Expect = 2e-12
Identities = 40/79 (50%), Positives = 46/79 (58%), Gaps = 15/79 (18%)
Query: 1063 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAG 1117
IP PP G + +PPPPPLP G G+PPPPP PPPPPLPG+ +P P
Sbjct: 560 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-----PPPPPPLPGMRMPFSGP----- 609
Query: 1118 IPPPPPLPGAGIPPPPPLP 1136
+PPPPPL G PPLP
Sbjct: 610 VPPPPPLGFLGGQNSPPLP 628
Score = 72.8 bits (177), Expect = 3e-12
Identities = 40/79 (50%), Positives = 45/79 (56%), Gaps = 15/79 (18%)
Query: 997 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1051
IP PP G + +PPPPPLP G G+PPPPP PPPPPLPG +P P
Sbjct: 560 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-----PPPPPPLPGMRMPFSGP----- 609
Query: 1052 IPPPPPLPGAGIPPPPPLP 1070
+PPPPPL G PPLP
Sbjct: 610 VPPPPPLGFLGGQNSPPLP 628
Score = 72.8 bits (177), Expect = 3e-12
Identities = 40/79 (50%), Positives = 45/79 (56%), Gaps = 15/79 (18%)
Query: 1030 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1084
IP PP G + +PPPPPLP G G+PPPPP PPPPPLPG +P P
Sbjct: 560 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-----PPPPPPLPGMRMPFSGP----- 609
Query: 1085 IPPPPPLPGAGIPPPPPLP 1103
+PPPPPL G PPLP
Sbjct: 610 VPPPPPLGFLGGQNSPPLP 628
Score = 72.8 bits (177), Expect = 3e-12
Identities = 40/79 (50%), Positives = 45/79 (56%), Gaps = 15/79 (18%)
Query: 1074 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAG 1128
IP PP G + +PPPPPLP G G+PPPPP PPPPPLPG +P P
Sbjct: 560 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-----PPPPPPLPGMRMPFSGP----- 609
Query: 1129 IPPPPPLPGAGIPPPPPLP 1147
+PPPPPL G PPLP
Sbjct: 610 VPPPPPLGFLGGQNSPPLP 628
Score = 71.6 bits (174), Expect = 6e-12
Identities = 40/79 (50%), Positives = 44/79 (55%), Gaps = 15/79 (18%)
Query: 1096 IPPPPPLPG----VGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVG 1150
IP PP G +PPPPPLP G G+PPPPP PPPPPLPG +P P
Sbjct: 560 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-----PPPPPPLPGMRMPFSGP----- 609
Query: 1151 IPPPPPLPGAGIPPPPPLP 1169
+PPPPPL G PPLP
Sbjct: 610 VPPPPPLGFLGGQNSPPLP 628
Score = 70.5 bits (171), Expect = 1e-11
Identities = 40/79 (50%), Positives = 45/79 (56%), Gaps = 15/79 (18%)
Query: 942 IPPPPPLPG----AAIPPPPPLP-GAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 996
IP PP G +A+PPPPPLP G G+P PPP PPPPPLPG +P P
Sbjct: 560 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-----PPPPPPLPGMRMPFSGP----- 609
Query: 997 IPPPPPLPGAGIPPPPPLP 1015
+PPPPPL G PPLP
Sbjct: 610 VPPPPPLGFLGGQNSPPLP 628
Score = 67.4 bits (163), Expect = 1e-10
Identities = 38/79 (48%), Positives = 42/79 (53%), Gaps = 13/79 (16%)
Query: 896 IPQPPPLQGT---EMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAA 952
IP PP +G LPPPPP G G+PPPPP P P PPLPG +P P
Sbjct: 560 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPPPP-----PPPPLPGMRMPFSGP----- 609
Query: 953 IPPPPPLPGAGIPLPPPLP 971
+PPPPPL G PPLP
Sbjct: 610 VPPPPPLGFLGGQNSPPLP 628
Score = 66.2 bits (160), Expect = 3e-10
Identities = 38/79 (48%), Positives = 44/79 (55%), Gaps = 15/79 (18%)
Query: 1041 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1095
IP PP G + +PPPPPLP G G+PPPPP PPPP P G+ P P
Sbjct: 560 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-------PPPPPPLPGMRMPFSGP--- 609
Query: 1096 IPPPPPLPGVGIPPPPPLP 1114
+PPPPPL +G PPLP
Sbjct: 610 VPPPPPLGFLGGQNSPPLP 628
Score = 65.9 bits (159), Expect = 3e-10
Identities = 38/79 (48%), Positives = 43/79 (54%), Gaps = 15/79 (18%)
Query: 1107 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAG 1161
IP PP G + +PPPPPLP G G+PPPPP PPPP P G+ P P
Sbjct: 560 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-------PPPPPPLPGMRMPFSGP--- 609
Query: 1162 IPPPPPLPGAGIPPPPPLP 1180
+PPPPPL G PPLP
Sbjct: 610 VPPPPPLGFLGGQNSPPLP 628
Score = 65.5 bits (158), Expect = 4e-10
Identities = 38/79 (48%), Positives = 43/79 (54%), Gaps = 15/79 (18%)
Query: 975 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1029
IP PP G + +PPPPPLP G G+PPPPP PPPP P G+ P P
Sbjct: 560 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-------PPPPPPLPGMRMPFSGP--- 609
Query: 1030 IPPPPPLPGAGIPPPPPLP 1048
+PPPPPL G PPLP
Sbjct: 610 VPPPPPLGFLGGQNSPPLP 628
Score = 65.5 bits (158), Expect = 4e-10
Identities = 38/79 (48%), Positives = 43/79 (54%), Gaps = 15/79 (18%)
Query: 986 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1040
IP PP G + +PPPPPLP G G+PPPPP PPPP P G+ P P
Sbjct: 560 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-------PPPPPPLPGMRMPFSGP--- 609
Query: 1041 IPPPPPLPGAGIPPPPPLP 1059
+PPPPPL G PPLP
Sbjct: 610 VPPPPPLGFLGGQNSPPLP 628
Score = 65.5 bits (158), Expect = 4e-10
Identities = 38/79 (48%), Positives = 43/79 (54%), Gaps = 15/79 (18%)
Query: 1008 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1062
IP PP G + +PPPPPLP G G+PPPPP PPPP P G+ P P
Sbjct: 560 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-------PPPPPPLPGMRMPFSGP--- 609
Query: 1063 IPPPPPLPGAGIPPPPPLP 1081
+PPPPPL G PPLP
Sbjct: 610 VPPPPPLGFLGGQNSPPLP 628
Score = 65.5 bits (158), Expect = 4e-10
Identities = 38/79 (48%), Positives = 43/79 (54%), Gaps = 15/79 (18%)
Query: 1019 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1073
IP PP G + +PPPPPLP G G+PPPPP PPPP P G+ P P
Sbjct: 560 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-------PPPPPPLPGMRMPFSGP--- 609
Query: 1074 IPPPPPLPGAGIPPPPPLP 1092
+PPPPPL G PPLP
Sbjct: 610 VPPPPPLGFLGGQNSPPLP 628
Score = 65.5 bits (158), Expect = 4e-10
Identities = 38/79 (48%), Positives = 43/79 (54%), Gaps = 15/79 (18%)
Query: 1052 IPPPPPLPG----AGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG 1106
IP PP G + +PPPPPLP G G+PPPPP PPPP P G+ P P
Sbjct: 560 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-------PPPPPPLPGMRMPFSGP--- 609
Query: 1107 IPPPPPLPGAGIPPPPPLP 1125
+PPPPPL G PPLP
Sbjct: 610 VPPPPPLGFLGGQNSPPLP 628
Score = 65.1 bits (157), Expect = 6e-10
Identities = 38/79 (48%), Positives = 44/79 (55%), Gaps = 15/79 (18%)
Query: 1085 IPPPPPLPG----AGIPPPPPLP-GVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1139
IP PP G + +PPPPPLP G G+PPPPP PPPP P G+ P P
Sbjct: 560 IPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPP-------PPPPPPLPGMRMPFSGP--- 609
Query: 1140 IPPPPPLPRVGIPPPPPLP 1158
+PPPPPL +G PPLP
Sbjct: 610 VPPPPPLGFLGGQNSPPLP 628
Score = 63.9 bits (154), Expect = 1e-09
Identities = 38/89 (42%), Positives = 44/89 (49%), Gaps = 23/89 (25%)
Query: 908 LPPPPPPLPGAG---IPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGI 964
+P PP G G +PPPPPLP G G+PPPPP PPPP P G+
Sbjct: 560 IPLPPSKEGGTGHSALPPPPPLPSGG----------GVPPPPP-------PPPPPPLPGM 602
Query: 965 PLPPPLPGAGIPPPPPLPGAGIPPPPPLP 993
+P P +PPPPPL G PPLP
Sbjct: 603 RMPFSGP---VPPPPPLGFLGGQNSPPLP 628
Score = 62.4 bits (150), Expect = 4e-09
Identities = 41/98 (41%), Positives = 44/98 (44%), Gaps = 29/98 (29%)
Query: 848 AFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPS-TAIPQPPPLQGTE 906
A CNIP PP S G +PPPPP LPS +P PPP
Sbjct: 553 ALPADCNIPLPP------SKEGGTGHSALPPPPP---------LPSGGGVPPPPP----- 592
Query: 907 MLPPPPPPLPG------AGIPPPPPLPGAGILPLPPLP 938
PPPPPPLPG +PPPPPL G PPLP
Sbjct: 593 --PPPPPPLPGMRMPFSGPVPPPPPLGFLGGQNSPPLP 628
Score = 61.2 bits (147), Expect = 8e-09
Identities = 38/85 (44%), Positives = 43/85 (50%), Gaps = 16/85 (18%)
Query: 926 LPGAGILPLPPLPGAG-----IPPPPPLP-GAAIPPPPPLPGAGIPLPPPLPGAGIPPPP 979
LP +PLPP G +PPPPPLP G +PPPPP P PP P G+ P
Sbjct: 554 LPADCNIPLPPSKEGGTGHSALPPPPPLPSGGGVPPPPPPP-------PPPPLPGMRMPF 606
Query: 980 PLPGAGIPPPPPLPGAGIPPPPPLP 1004
P +PPPPPL G PPLP
Sbjct: 607 SGP---VPPPPPLGFLGGQNSPPLP 628
Score = 51.2 bits (121), Expect = 8e-06
Identities = 29/68 (42%), Positives = 34/68 (50%), Gaps = 6/68 (8%)
Query: 855 IPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPP 914
+P PPPLP P PPPPPPLPGM +P S +P PPPL PP P
Sbjct: 575 LPPPPPLPSGGGVPPPPP----PPPPPPLPGMRMPF--SGPVPPPPPLGFLGGQNSPPLP 628
Query: 915 LPGAGIPP 922
+ G+ P
Sbjct: 629 ILPFGLKP 636
>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 1691
Score = 168 bits (425), Expect = 5e-41
Identities = 224/694 (32%), Positives = 260/694 (37%), Gaps = 196/694 (28%)
Query: 750 EEGGVLTLPPVDGLPGRP--------PCPPGAESGPQTKFCSEISLIVSPRRISVQLDSH 801
+ G +T P GLPG P P PG P P + +
Sbjct: 654 DPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGL-----------PGIPGSKGEPG 702
Query: 802 QPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPP-- 859
P + PP P G PG PP + T + E P PP
Sbjct: 703 IPGIGLPGPPGPKGF-----PGIPG--PPGAPGTPGRIGLE-----------GPPGPPGF 744
Query: 860 PLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPS-----TAIPQPPPLQGTEMLPPP--- 911
P P E ++PG PP PP LPG P P PP G + LP P
Sbjct: 745 PGPKGEPGFALPG----PPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGD 800
Query: 912 -----------PPPLPGAGI---PPPPPLPG-AGILPLPPLPGAGIPPPPPLPGAAIPPP 956
PP LPG G+ P PP +PG G L +PG P P PG +P P
Sbjct: 801 VGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGP--PGLDVPGP 858
Query: 957 ------PPLPGAGIPLPPP----LPG----AGIP----------PPPPLPGAGIPPPPPL 992
P +PGA P+ PP LPG +G P PP P GIP +
Sbjct: 859 PGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGV 918
Query: 993 PGA----GIPPPPPLPG----AGIPPPPPLPGAGIPPPPPLPGA----GIPPPPPLPGA- 1039
PG G+ P LPG G P LPG P P L G+ G P P +PG
Sbjct: 919 PGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVS 978
Query: 1040 ------GIPPPPPLPG----AGIPPP------PPLPG-AGIPPPPPLPGA----GIP--- 1075
G+P P PG G+P P P LPG G+ PP L G G P
Sbjct: 979 GPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQ 1038
Query: 1076 ----PPPPLPGAGIPPPPPLPG---------------AGIPPPPPLPGV-GIPPPPPLPG 1115
PP P G P P LPG G+P P PG+ G P P + G
Sbjct: 1039 GVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKG 1098
Query: 1116 A-GIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIP-PPPPLPGAG 1172
+ G P P LPG G P LPG P PP P+ GI PP P G+P P P+ G G
Sbjct: 1099 SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK-GISGPPGNP--GLPGEPGPVGGGG 1155
Query: 1173 IPPPPPLPGV-------GIPPP------PPLPGVGIPPPPPLPG----------AGIPPP 1209
P P PG GIP P P PG G P PP LPG GIP
Sbjct: 1156 HPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGN 1215
Query: 1210 PPLPG-------MGIPPAPAPPLPP--PGTGIPPPPLLP-VSGPPLLP-QVGSSTLPTPQ 1258
P LPG G P PP PP PG + P P GPP P G LP P+
Sbjct: 1216 PGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPE 1275
Query: 1259 VCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRP 1292
PP LP G+ +KG+ QP P P
Sbjct: 1276 G----PPGLPG---NGGIKGEKGNPGQPGLPGLP 1302
Score = 163 bits (412), Expect = 2e-39
Identities = 175/492 (35%), Positives = 198/492 (40%), Gaps = 92/492 (18%)
Query: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMT-VPTLPST-AIPQPPPLQGTEMLPPPPP 913
P P LP PG G PP P G+ V P IP P G + P P
Sbjct: 608 PGLPGLPGNIGPMGPPGFG--PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKP 665
Query: 914 PLPG-------AGIPPPPPLPGAGILP-------LPPLPGAGIPPPPPLPG-AAIPPPPP 958
LPG G+P P LPG LP P +PG G+P PP G IP PP
Sbjct: 666 GLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG 725
Query: 959 LPGA-------GIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPG----------AGIPPPP 1001
PG G P PP PG P LPG P PP LPG G P PP
Sbjct: 726 APGTPGRIGLEGPPGPPGFPGPKGEPGFALPGP--PGPPGLPGFKGALGPKGDRGFPGPP 783
Query: 1002 PLPGA----GIPPPPPLPGAGIPP----PPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GI 1052
PG G+P P G P PP LPG G+ PP P GIP P PG GI
Sbjct: 784 GPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPP--GIPGPIGQPGLHGI 841
Query: 1053 P---PPPPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPLPG----AGIPPPPPLPG 1104
P P PG +P PP G+ P P PG G P P LPG +G P G
Sbjct: 842 PGEKGDPGPPGLDVPGPPGERGS--PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMG 899
Query: 1105 VGIPPPPPLPGAGIPPPPPLPGA----GIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGA 1160
+ PP PP P GIP +PG G+ P LPG P G P LPG
Sbjct: 900 MMGPPGPPGP-LGIPGRSGVPGLKGDDGLQGQPGLPG-------PTGEKGSKGEPGLPGP 951
Query: 1161 GIPPPPPLPGA-GIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGM-GIP 1218
P P L G+ G P LPG+ PGV P G+P P PG+ G P
Sbjct: 952 PGPMDPNLLGSKGEKGEPGLPGI--------PGVS----GPKGYQGLPGDPGQPGLSGQP 999
Query: 1219 PAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGL---- 1274
P PP P G+P P L + P L +G P PQ G PP PSG+ G
Sbjct: 1000 GLPGPPGPKGNPGLPGQPGL-IGPPGLKGTIGDMGFPGPQ--GVEGPPGPSGVPGQPGSP 1056
Query: 1275 GMNQDKGSRKQP 1286
G+ KG + P
Sbjct: 1057 GLPGQKGDKGDP 1068
Score = 155 bits (393), Expect = 2e-37
Identities = 214/663 (32%), Positives = 248/663 (37%), Gaps = 157/663 (23%)
Query: 759 PVDGLPGRP--------PCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQP 810
P GLPG P P PPGA P I L P +P ++ P
Sbjct: 704 PGIGLPGPPGPKGFPGIPGPPGAPGTP-----GRIGLEGPPGPPGFPGPKGEPGFALPGP 758
Query: 811 PPPPSLLWSAG-------QGQPGSQ-PPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLP 862
P PP L G +G PG PP + + V N P PP
Sbjct: 759 PGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGP---NGQPGPMGPP-- 813
Query: 863 CTESSSSMPGLGMVPPPPPP-------------LPGMTV-PTLPSTAIPQPPPLQGTEML 908
+PG+G+ PP PP +PG P P +P PP +G+ +
Sbjct: 814 ------GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGI 867
Query: 909 PPPPPPLPGAGIPPPPPLPG-AGILPLPPLPGA-GIPPPPPLPGA-AIPPPPPLPGA--- 962
P P P+ G P P LPG AG P G G+ PP PG IP +PG
Sbjct: 868 PGAPGPI---GPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924
Query: 963 -GIPLPPPLPGA----GIPPPPPLPGAGIPPPPPLPGA----GIPPPPPLPGA------- 1006
G+ P LPG G P LPG P P L G+ G P P +PG
Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984
Query: 1007 GIPPPPPLPGA----GIPPPPP------LPGA-GIPPPPPLPGA----GIPPP-----PP 1046
G+P P PG G+P PP LPG G+ PP L G G P P PP
Sbjct: 985 GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044
Query: 1047 LPGA--GIPPPPPLPGA---------------GIPPPPPLPGA-GIPPPPPLPGA----G 1084
P G P P LPG G+P P PG G P P + G+ G
Sbjct: 1045 GPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPG 1104
Query: 1085 IPPPPPLPGA-GIPPPPPLPGVGIPPPP-----PLPGAGIPPPP-PLPGAGIPPPPPLPG 1137
+P P PGA G P P PG PP P P G+P P P+ G G P P PG
Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164
Query: 1138 A-------GIPPP------PPLPRVGIPPPPPLPGA----------GIPPPPPLPGA-GI 1173
GIP P P P G P PP LPG GIP P LPG G
Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE 1224
Query: 1174 PPPPPLPGVGIPPPPP-LPGVGIPPPPPLPGAGIPP--PPPLPGMGIPPAPAPPLPPPGT 1230
P PGV PP PP PG + P PG PP P P G+P PP P
Sbjct: 1225 PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNG 1284
Query: 1231 GIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGL-GMNQDKGSRKQPIEP 1289
GI P G P LP + P + G PP G G G+N KG P P
Sbjct: 1285 GIKGEKGNP--GQPGLPGL-------PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVP 1335
Query: 1290 CRP 1292
P
Sbjct: 1336 GFP 1338
Score = 153 bits (387), Expect = 1e-36
Identities = 212/642 (33%), Positives = 240/642 (37%), Gaps = 162/642 (25%)
Query: 748 PTEEG--GVLTLPPVDGLPGRPPCP--PGAESGPQTKFCSEISLIVSPRRISVQLDSHQP 803
P E G G+ P G PG P P GA P TK E+ ++ P
Sbjct: 859 PGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTK--GEMGMMGPPG----------- 905
Query: 804 TQSISQPPPPPSLLWSAG----------QGQPGSQPPHSISTEFQTSHEHSVSSAFKNSC 853
PP P + +G QGQPG P T + S
Sbjct: 906 ------PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP--------TGEKGSKGEPGLPGP 951
Query: 854 NIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPT----LPSTAIPQPPPLQGTEMLP 909
P P L ++ PGL P +PG++ P LP P P L G LP
Sbjct: 952 PGPMDPNLLGSKGEKGEPGL-------PGIPGVSGPKGYQGLPGD--PGQPGLSGQPGLP 1002
Query: 910 PPPPPLPGAGIPPPPPLPGA-------GILPLPPLPGAGIPPPPP-LPGAAIPPPPPLPG 961
PP P G+P P L G G + P G PP P +PG P P LPG
Sbjct: 1003 GPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQ--PGSPGLPG 1060
Query: 962 A------------GIP-LPPPLPGAGIPPPPPLPG----AGIPPPPPLPGA-GIPPPPPL 1003
G+P LP P G+P P PG G P P LPG G P L
Sbjct: 1061 QKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGL 1120
Query: 1004 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGAGIPPPPPLPGA-GIPPPPPLPG- 1060
PG P PP P GI PP PG +P P P+ G G P P PG G P +PG
Sbjct: 1121 PGFPGTPGPPGP-KGISGPPGNPG--LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGP 1177
Query: 1061 AGIPPPPPLPGAGIPPPPPLPGA----------GIPPPPPLPGA-GIPPPPPLPGVGIPP 1109
AG P PG G P PP LPG GIP P LPG G P PGV PP
Sbjct: 1178 AGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPP 1237
Query: 1110 PPP-LPGAGIPPPPPLPGAGIPP--PPPLPGAGIPPP---PPLP-------RVGIPPPPP 1156
PP PG + P PG PP P P G+P P P LP G P P
Sbjct: 1238 GPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPG 1297
Query: 1157 LPGA----GIPPPPPLPGA-------GIPPPPPLPGV----GIPPPPPLPG--------- 1192
LPG G PP L G G+ P LPGV G+ P +PG
Sbjct: 1298 LPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPG 1357
Query: 1193 -VGIPPPPPLPG-----------AGIPPPPPLPGMGIPPAPAPPLPPPG-TGIPPPPLLP 1239
+G P PP LPG AG P P PG+ P P P PG TG P P
Sbjct: 1358 LIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDP--- 1414
Query: 1240 VSGPPLLP-------QVGSSTLP-TPQVCGFLPPPLPSGLFG 1273
G LP + G LP P G PP P GL G
Sbjct: 1415 --GRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQG 1454
Score = 148 bits (373), Expect = 5e-35
Identities = 195/583 (33%), Positives = 224/583 (38%), Gaps = 95/583 (16%)
Query: 753 GVLTLPPVDGLPGRPPCP-PGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPP 811
GV L DGL G+P P P E G + E L P + L + + P
Sbjct: 917 GVPGLKGDDGLQGQPGLPGPTGEKGSK----GEPGLPGPPGPMDPNLLGSKGEKGEPGLP 972
Query: 812 PPPSLLWSAG-QGQPGS--QPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSS 868
P + G QG PG QP S + + PP L T
Sbjct: 973 GIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDM 1032
Query: 869 SMPGLGMVPPPPPP--LPGMT-VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPP 925
PG V PP P +PG P LP + P + LP P P G+P P
Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPG 1092
Query: 926 LPG----AGILPLPPLPGA-GIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPP- 979
PG G LP LPG G P LPG P PP P GI PP PG +P P
Sbjct: 1093 NPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGP-KGISGPPGNPG--LPGEPG 1149
Query: 980 PLPGAGIPPPPPLPGA-GIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGA--------- 1028
P+ G G P P PG G P +PG AG P PG G P PP LPG
Sbjct: 1150 PVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL 1209
Query: 1029 -GIPPPPPLPGA-GIPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGAGIPP--PPPLPGA 1083
GIP P LPG G P PG PP PP PG + P PG PP P P
Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQ 1269
Query: 1084 GIPPP---PPLPG-------AGIPPPPPLPGV----GIPPPPPLPGA-------GIPPPP 1122
G+P P P LPG G P P LPG+ G PP L G G+ P
Sbjct: 1270 GLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDP 1329
Query: 1123 PLPGA----GIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGA--------GIPPPPPLPG 1170
LPG G+ P +PG+ P P +G P PP LPG G PP
Sbjct: 1330 GLPGVPGFPGMKGPSGVPGSAGPEGEP-GLIGPPGPPGLPGPSGQSIIIKGDAGPP---- 1384
Query: 1171 AGIPPPPPLPGVGIPPPPP-LPGVGIPPPPP----LPG----------AGIPPPPPLPGM 1215
GIP P L G+ P P LPG PP P LPG G+P P G+
Sbjct: 1385 -GIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGL 1443
Query: 1216 GIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQ 1258
PP P PPG PP V+ L+ + S T PQ
Sbjct: 1444 DGPPGPDGLQGPPG----PPGTSSVAHGFLITR-HSQTTDAPQ 1481
Score = 139 bits (349), Expect = 3e-32
Identities = 211/676 (31%), Positives = 240/676 (35%), Gaps = 160/676 (23%)
Query: 751 EGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQP 810
E G P ++G PG P P G E P + I P + I P
Sbjct: 46 EKGERGFPGLEGHPGLPGFP-GPEGPPGPRGQKGDDGIPGP----------PGPKGIRGP 94
Query: 811 PPPPSLLWSAG----QGQPGSQPPHSISTEFQTSHEHSV--SSAFKNSCNIPSPPPLPCT 864
P P + G G G+ P I T E S F P PP +P
Sbjct: 95 PGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGM 154
Query: 865 ESS------SSMPGLGMVP--PPPPPLPGMTVPT-LPST-AIPQPPPLQGTEMLPPPPPP 914
+ SS+PG P P PP + G+ PT +P P PP L G PP PP
Sbjct: 155 KGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG----PPGPPG 210
Query: 915 LPGA------------------GIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPP 956
LPG G+ PP PG P+ LPG PP
Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPG 270
Query: 957 PPLPGAGIPLPPPLPGA--------GIPPPPPLPGA----GIPPPPPLPG-AGIPPPPPL 1003
PP GI PP PG G P PG G P P LPG G P P
Sbjct: 271 PP----GIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326
Query: 1004 PGA----GIPPPPPLPGAGIPPP--------------PPLPGA-------GIPPPPPLPG 1038
G G PP PG IP P P LPG GI PP LPG
Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386
Query: 1039 AGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPL---PGA-GIPPPPPLPG 1093
PP G P PP PG G PG IP PP L PGA G+P PP G
Sbjct: 387 -----PPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAG 441
Query: 1094 AGIPPPPPLPGVGIPPPPPLPG-----------------------AGIPPPPPLPGA-GI 1129
IPP + G P PP PG GI PP PG G+
Sbjct: 442 PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGL 501
Query: 1130 PPPPP---LPG-------AGIPPPPPLPRV-GIPPPPPLPGAGIPPPPPL--PGA----- 1171
P PP PG AG P LP + G P P PG+ P L PG
Sbjct: 502 PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKG 561
Query: 1172 --GIPPPPPLPGV-GIPPPPPLPGVGIPPPPPLPGA----GIPPPPPLPGMGIPPAPAPP 1224
G P P LPG+ G P LPG +P P PG G PP PG+ P P
Sbjct: 562 ELGSPGAPGLPGLPGTPGQDGLPG--LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGP 619
Query: 1225 LPPPGTGIPPP----PLLPVSGPPLLPQV-GSSTLPTPQVCGFLPPPLPS--GLFG-LGM 1276
+ PPG G P P + V+G P P + G P + P LP G G +G+
Sbjct: 620 MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL 679
Query: 1277 NQDKGSRKQPIEPCRP 1292
D G QP P P
Sbjct: 680 PGDPGLPGQPGLPGIP 695
Score = 55.1 bits (131), Expect = 6e-07
Identities = 74/258 (28%), Positives = 93/258 (36%), Gaps = 44/258 (17%)
Query: 748 PTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPT--Q 805
P E G P V G PG P P A GP+ + P R PT Q
Sbjct: 1221 PKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ----GPPGRPG-------PTGFQ 1269
Query: 806 SISQPPPPPSLLWSAG-------QGQPGSQPPHSISTE-----FQTSHEHSVSSAFKNSC 853
+ P PP L + G GQPG + + Q + + K
Sbjct: 1270 GLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDP 1329
Query: 854 NIPSPPPLPCTESSSSMPGL-------GMVPPPPPP-LPGMTVPTLPSTAIPQPPPLQGT 905
+P P P + S +PG G++ PP PP LPG + ++ PP + G
Sbjct: 1330 GLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQ 1389
Query: 906 EMLPPPPPPLPGAGIPPPPPLPG-AGILPLPPLPGA-GIPPPPPLPGAAIPPPPPLPGA- 962
L P P G+P P PG G LP GA G P LPG PG
Sbjct: 1390 PGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQ--------PGTR 1441
Query: 963 GIPLPPPLPGAGIPPPPP 980
G+ PP G PP PP
Sbjct: 1442 GLDGPPGPDGLQGPPGPP 1459
Score = 44.3 bits (103), Expect = 0.001
Identities = 49/159 (30%), Positives = 57/159 (35%), Gaps = 18/159 (11%)
Query: 255 GPSGGAGEAPGSP----------DTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEA 304
GPSG G+ PGSP D + L LP EP P P +PG
Sbjct: 1045 GPSGVPGQ-PGSPGLPGQKGDKGDPGISSIGLPGLPGP-KGEPGLPGYPGNPGIKGSVGD 1102
Query: 305 PSLPA--AQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGE-EDAFEDAPRGS 361
P LP P AK P FP PG + P G E G G
Sbjct: 1103 PGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGP 1162
Query: 362 PGEEWAPEVGEDA-PQRLGEEPEEEAQGPDAPAAASLPG 399
PGE+ P G+D P G++ E G P LPG
Sbjct: 1163 PGEKGKP--GQDGIPGPAGQKGEPGQPGFGNPGPPGLPG 1199
Score = 39.3 bits (90), Expect = 0.033
Identities = 58/241 (24%), Positives = 78/241 (32%), Gaps = 45/241 (18%)
Query: 227 QGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTE-----QALSALSDLPE 281
+G P PP V P+PG + +G G G PG P + + LP
Sbjct: 333 KGDTGPPGPPGLVIPRPGTGI-----TIGEKGNIG-LPGLPGEKGERGFPGIQGPPGLPG 386
Query: 282 SLAAEPREPQQPP------------SPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAG 329
A P PP P G+ + P L QP A P P
Sbjct: 387 PPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLD-GQPGAPGLPGPPGPAGPHIP 445
Query: 330 PGEE----AAGAPVRGAGDTDEEGEEDAFED--------------APRGSPGEEW--APE 369
P +E P GD +GE+ D P G PG P
Sbjct: 446 PSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505
Query: 370 VGEDAPQRLGEEPEEEAQGPDA-PAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSS 428
P + GE+ + A GP P PG+P +P ++T +K +L S
Sbjct: 506 GSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGS 565
Query: 429 P 429
P
Sbjct: 566 P 566
Score = 36.2 bits (82), Expect = 0.28
Identities = 47/181 (25%), Positives = 61/181 (33%), Gaps = 38/181 (20%)
Query: 236 PTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPS 295
P + QPGA L GP G AG P P +++ EP P P S
Sbjct: 421 PPGLDGQPGA-----PGLPGPPGPAG--PHIPPSDEI------------CEPGPPGPPGS 461
Query: 296 PGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEE-DAF 354
PG + + + + T P PG P G ++GE+ A
Sbjct: 462 PGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAG 521
Query: 355 EDAPRGSPGEEWAPEVGEDAPQRLGEEPEE--------------EAQGPDAPAAASLPGS 400
P+G PG AP AP G + E E P AP LPG+
Sbjct: 522 ATGPKGLPGIPGAP----GAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT 577
Query: 401 P 401
P
Sbjct: 578 P 578
Score = 33.1 bits (74), Expect = 2.4
Identities = 44/176 (25%), Positives = 60/176 (34%), Gaps = 17/176 (9%)
Query: 231 EPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEA--PGSPDTEQALSALSDLPESLAAEPR 288
+P P +S QPG L GP G G PG P + + P+
Sbjct: 989 DPGQP--GLSGQPG--------LPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQ 1038
Query: 289 EPQQPPSPGGLPVSE-APSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDE 347
+ PP P G+P +P LP Q K P ++ P + G P +
Sbjct: 1039 GVEGPPGPSGVPGQPGSPGLP-GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIK 1097
Query: 348 EGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAP 403
D G+PG + P + P G + GP P LPG P P
Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGL-PGFPGTPGPPGPKGISGP--PGNPGLPGEPGP 1150
>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
sapiens]
Length = 1688
Score = 168 bits (425), Expect = 5e-41
Identities = 224/693 (32%), Positives = 260/693 (37%), Gaps = 197/693 (28%)
Query: 750 EEGGVLTLPPVDGLPGRP--------PCPPGAESGPQTKFCSEISLIVSPRRISVQLDSH 801
+ G +T P GLPG P P PG P P + +
Sbjct: 654 DPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGL-----------PGIPGSKGEPG 702
Query: 802 QPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPP-- 859
P + PP P G PG PP + T + E P PP
Sbjct: 703 IPGIGLPGPPGPKGF-----PGIPG--PPGAPGTPGRIGLE-----------GPPGPPGF 744
Query: 860 PLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPS-----TAIPQPPPLQGTEMLPPP--- 911
P P E ++PG PP PP LPG P P PP G + LP P
Sbjct: 745 PGPKGEPGFALPG----PPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGD 800
Query: 912 -----------PPPLPGAGI---PPPPPLPG-AGILPLPPLPGAGIPPPPPLPGAAIPPP 956
PP LPG G+ P PP +PG G L +PG P P PG +P P
Sbjct: 801 VGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGP--PGLDVPGP 858
Query: 957 ------PPLPGAGIPLPPP----LPG----AGIP----------PPPPLPGAGIPPPPPL 992
P +PGA P+ PP LPG +G P PP P GIP +
Sbjct: 859 PGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGV 918
Query: 993 PGA----GIPPPPPLPG----AGIPPPPPLPGAGIPPPPPLPGA----GIPPPPPLPGA- 1039
PG G+ P LPG G P LPG P P L G+ G P P +PG
Sbjct: 919 PGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVS 978
Query: 1040 ------GIPPPPPLPG----AGIPPP------PPLPG-AGIPPPPPLPGA----GIP--- 1075
G+P P PG G+P P P LPG G+ PP L G G P
Sbjct: 979 GPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQ 1038
Query: 1076 ----PPPPLPGAGIPPPPPLPG---------------AGIPPPPPLPGV-GIPPPPPLPG 1115
PP P G P P LPG G+P P PG+ G P P + G
Sbjct: 1039 GVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKG 1098
Query: 1116 A-GIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIP-PPPPLPGAG 1172
+ G P P LPG G P LPG P PP P+ GI PP P G+P P P+ G G
Sbjct: 1099 SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK-GISGPPGNP--GLPGEPGPVGGGG 1155
Query: 1173 IPPPPPLPGV-------GIPPP------PPLPGVGIPPPPPLPG----------AGIPPP 1209
P P PG GIP P P PG G P PP LPG GIP
Sbjct: 1156 HPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGN 1215
Query: 1210 PPLPG-------MGIPPAPAPPLPP--PGTGIPPPPLLP-VSGPPLLPQVGSSTLPTPQV 1259
P LPG G P PP PP PG + P P GPP P G LP P+
Sbjct: 1216 PGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRP--GFQGLPGPEG 1273
Query: 1260 CGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRP 1292
PP LP G+ +KG+ QP P P
Sbjct: 1274 ----PPGLPG---NGGIKGEKGNPGQPGLPGLP 1299
Score = 163 bits (412), Expect = 2e-39
Identities = 175/492 (35%), Positives = 198/492 (40%), Gaps = 92/492 (18%)
Query: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMT-VPTLPST-AIPQPPPLQGTEMLPPPPP 913
P P LP PG G PP P G+ V P IP P G + P P
Sbjct: 608 PGLPGLPGNIGPMGPPGFG--PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKP 665
Query: 914 PLPG-------AGIPPPPPLPGAGILP-------LPPLPGAGIPPPPPLPG-AAIPPPPP 958
LPG G+P P LPG LP P +PG G+P PP G IP PP
Sbjct: 666 GLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG 725
Query: 959 LPGA-------GIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPG----------AGIPPPP 1001
PG G P PP PG P LPG P PP LPG G P PP
Sbjct: 726 APGTPGRIGLEGPPGPPGFPGPKGEPGFALPGP--PGPPGLPGFKGALGPKGDRGFPGPP 783
Query: 1002 PLPGA----GIPPPPPLPGAGIPP----PPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GI 1052
PG G+P P G P PP LPG G+ PP P GIP P PG GI
Sbjct: 784 GPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPP--GIPGPIGQPGLHGI 841
Query: 1053 P---PPPPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPLPG----AGIPPPPPLPG 1104
P P PG +P PP G+ P P PG G P P LPG +G P G
Sbjct: 842 PGEKGDPGPPGLDVPGPPGERGS--PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMG 899
Query: 1105 VGIPPPPPLPGAGIPPPPPLPGA----GIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGA 1160
+ PP PP P GIP +PG G+ P LPG P G P LPG
Sbjct: 900 MMGPPGPPGP-LGIPGRSGVPGLKGDDGLQGQPGLPG-------PTGEKGSKGEPGLPGP 951
Query: 1161 GIPPPPPLPGA-GIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGM-GIP 1218
P P L G+ G P LPG+ PGV P G+P P PG+ G P
Sbjct: 952 PGPMDPNLLGSKGEKGEPGLPGI--------PGVS----GPKGYQGLPGDPGQPGLSGQP 999
Query: 1219 PAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGL---- 1274
P PP P G+P P L + P L +G P PQ G PP PSG+ G
Sbjct: 1000 GLPGPPGPKGNPGLPGQPGL-IGPPGLKGTIGDMGFPGPQ--GVEGPPGPSGVPGQPGSP 1056
Query: 1275 GMNQDKGSRKQP 1286
G+ KG + P
Sbjct: 1057 GLPGQKGDKGDP 1068
Score = 153 bits (387), Expect = 1e-36
Identities = 214/662 (32%), Positives = 248/662 (37%), Gaps = 158/662 (23%)
Query: 759 PVDGLPGRP--------PCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQP 810
P GLPG P P PPGA P I L P +P ++ P
Sbjct: 704 PGIGLPGPPGPKGFPGIPGPPGAPGTP-----GRIGLEGPPGPPGFPGPKGEPGFALPGP 758
Query: 811 PPPPSLLWSAG-------QGQPGSQ-PPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLP 862
P PP L G +G PG PP + + V N P PP
Sbjct: 759 PGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGP---NGQPGPMGPP-- 813
Query: 863 CTESSSSMPGLGMVPPPPPP-------------LPGMTV-PTLPSTAIPQPPPLQGTEML 908
+PG+G+ PP PP +PG P P +P PP +G+ +
Sbjct: 814 ------GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGI 867
Query: 909 PPPPPPLPGAGIPPPPPLPG-AGILPLPPLPGA-GIPPPPPLPGA-AIPPPPPLPGA--- 962
P P P+ G P P LPG AG P G G+ PP PG IP +PG
Sbjct: 868 PGAPGPI---GPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924
Query: 963 -GIPLPPPLPGA----GIPPPPPLPGAGIPPPPPLPGA----GIPPPPPLPGA------- 1006
G+ P LPG G P LPG P P L G+ G P P +PG
Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984
Query: 1007 GIPPPPPLPGA----GIPPPPP------LPGA-GIPPPPPLPGA----GIPPP-----PP 1046
G+P P PG G+P PP LPG G+ PP L G G P P PP
Sbjct: 985 GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044
Query: 1047 LPGA--GIPPPPPLPGA---------------GIPPPPPLPGA-GIPPPPPLPGA----G 1084
P G P P LPG G+P P PG G P P + G+ G
Sbjct: 1045 GPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPG 1104
Query: 1085 IPPPPPLPGA-GIPPPPPLPGVGIPPPP-----PLPGAGIPPPP-PLPGAGIPPPPPLPG 1137
+P P PGA G P P PG PP P P G+P P P+ G G P P PG
Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164
Query: 1138 A-------GIPPP------PPLPRVGIPPPPPLPGA----------GIPPPPPLPGA-GI 1173
GIP P P P G P PP LPG GIP P LPG G
Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE 1224
Query: 1174 PPPPPLPGVGIPPPPP-LPGVGIPPPPPLPGAGIPPPPPLPG-MGIPPAPAPPLPPPGTG 1231
P PGV PP PP PG + P PG PP PG G+P PP P G
Sbjct: 1225 PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP--QGPPGRPGFQGLPGPEGPPGLPGNGG 1282
Query: 1232 IPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGL-GMNQDKGSRKQPIEPC 1290
I P G P LP + P + G PP G G G+N KG P P
Sbjct: 1283 IKGEKGNP--GQPGLPGL-------PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPG 1333
Query: 1291 RP 1292
P
Sbjct: 1334 FP 1335
Score = 152 bits (385), Expect = 2e-36
Identities = 211/639 (33%), Positives = 238/639 (37%), Gaps = 159/639 (24%)
Query: 748 PTEEG--GVLTLPPVDGLPGRPPCP--PGAESGPQTKFCSEISLIVSPRRISVQLDSHQP 803
P E G G+ P G PG P P GA P TK E+ ++ P
Sbjct: 859 PGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTK--GEMGMMGPPG----------- 905
Query: 804 TQSISQPPPPPSLLWSAG----------QGQPGSQPPHSISTEFQTSHEHSVSSAFKNSC 853
PP P + +G QGQPG P T + S
Sbjct: 906 ------PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP--------TGEKGSKGEPGLPGP 951
Query: 854 NIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPT----LPSTAIPQPPPLQGTEMLP 909
P P L ++ PGL P +PG++ P LP P P L G LP
Sbjct: 952 PGPMDPNLLGSKGEKGEPGL-------PGIPGVSGPKGYQGLPGD--PGQPGLSGQPGLP 1002
Query: 910 PPPPPLPGAGIPPPPPLPGA-------GILPLPPLPGAGIPPPPP-LPGAAIPPPPPLPG 961
PP P G+P P L G G + P G PP P +PG P P LPG
Sbjct: 1003 GPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQ--PGSPGLPG 1060
Query: 962 A------------GIP-LPPPLPGAGIPPPPPLPG----AGIPPPPPLPGA-GIPPPPPL 1003
G+P LP P G+P P PG G P P LPG G P L
Sbjct: 1061 QKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGL 1120
Query: 1004 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGAGIPPPPPLPGA-GIPPPPPLPG- 1060
PG P PP P GI PP PG +P P P+ G G P P PG G P +PG
Sbjct: 1121 PGFPGTPGPPGP-KGISGPPGNPG--LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGP 1177
Query: 1061 AGIPPPPPLPGAGIPPPPPLPGA----------GIPPPPPLPGA-GIPPPPPLPGVGIPP 1109
AG P PG G P PP LPG GIP P LPG G P PGV PP
Sbjct: 1178 AGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPP 1237
Query: 1110 PPP-LPGAGIPPPPPLPGAGIPPPPP----LPGAGIPPPPP-----LPRVGIPPPPPLPG 1159
PP PG + P PG PP P LPG PP P G P P LPG
Sbjct: 1238 GPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPG 1297
Query: 1160 A----GIPPPPPLPGA-------GIPPPPPLPGV----GIPPPPPLPG----------VG 1194
G PP L G G+ P LPGV G+ P +PG +G
Sbjct: 1298 LPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIG 1357
Query: 1195 IPPPPPLPG-----------AGIPPPPPLPGMGIPPAPAPPLPPPG-TGIPPPPLLPVSG 1242
P PP LPG AG P P PG+ P P P PG TG P P G
Sbjct: 1358 PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDP-----G 1412
Query: 1243 PPLLP-------QVGSSTLP-TPQVCGFLPPPLPSGLFG 1273
LP + G LP P G PP P GL G
Sbjct: 1413 RNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQG 1451
Score = 147 bits (370), Expect = 1e-34
Identities = 194/580 (33%), Positives = 222/580 (38%), Gaps = 92/580 (15%)
Query: 753 GVLTLPPVDGLPGRPPCP-PGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPP 811
GV L DGL G+P P P E G + E L P + L + + P
Sbjct: 917 GVPGLKGDDGLQGQPGLPGPTGEKGSK----GEPGLPGPPGPMDPNLLGSKGEKGEPGLP 972
Query: 812 PPPSLLWSAG-QGQPGS--QPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSS 868
P + G QG PG QP S + + PP L T
Sbjct: 973 GIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDM 1032
Query: 869 SMPGLGMVPPPPPP--LPGMT-VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPP 925
PG V PP P +PG P LP + P + LP P P G+P P
Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPG 1092
Query: 926 LPG----AGILPLPPLPGA-GIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPP- 979
PG G LP LPG G P LPG P PP P GI PP PG +P P
Sbjct: 1093 NPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGP-KGISGPPGNPG--LPGEPG 1149
Query: 980 PLPGAGIPPPPPLPGA-GIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGA--------- 1028
P+ G G P P PG G P +PG AG P PG G P PP LPG
Sbjct: 1150 PVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL 1209
Query: 1029 -GIPPPPPLPGA-GIPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGAGIPPPPP----LP 1081
GIP P LPG G P PG PP PP PG + P PG PP P LP
Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLP 1269
Query: 1082 GAGIPPPPPLPGA-----GIPPPPPLPGV----GIPPPPPLPGA-------GIPPPPPLP 1125
G PP P G G P P LPG+ G PP L G G+ P LP
Sbjct: 1270 GPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLP 1329
Query: 1126 GA----GIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGA--------GIPPPPPLPGAGI 1173
G G+ P +PG+ P P +G P PP LPG G PP GI
Sbjct: 1330 GVPGFPGMKGPSGVPGSAGPEGEP-GLIGPPGPPGLPGPSGQSIIIKGDAGPP-----GI 1383
Query: 1174 PPPPPLPGVGIPPPPP-LPGVGIPPPPP----LPG----------AGIPPPPPLPGMGIP 1218
P P L G+ P P LPG PP P LPG G+P P G+ P
Sbjct: 1384 PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP 1443
Query: 1219 PAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQ 1258
P P PPG PP V+ L+ + S T PQ
Sbjct: 1444 PGPDGLQGPPG----PPGTSSVAHGFLITR-HSQTTDAPQ 1478
Score = 139 bits (349), Expect = 3e-32
Identities = 211/676 (31%), Positives = 240/676 (35%), Gaps = 160/676 (23%)
Query: 751 EGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQP 810
E G P ++G PG P P G E P + I P + I P
Sbjct: 46 EKGERGFPGLEGHPGLPGFP-GPEGPPGPRGQKGDDGIPGP----------PGPKGIRGP 94
Query: 811 PPPPSLLWSAG----QGQPGSQPPHSISTEFQTSHEHSV--SSAFKNSCNIPSPPPLPCT 864
P P + G G G+ P I T E S F P PP +P
Sbjct: 95 PGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGM 154
Query: 865 ESS------SSMPGLGMVP--PPPPPLPGMTVPT-LPST-AIPQPPPLQGTEMLPPPPPP 914
+ SS+PG P P PP + G+ PT +P P PP L G PP PP
Sbjct: 155 KGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG----PPGPPG 210
Query: 915 LPGA------------------GIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPP 956
LPG G+ PP PG P+ LPG PP
Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPG 270
Query: 957 PPLPGAGIPLPPPLPGA--------GIPPPPPLPGA----GIPPPPPLPG-AGIPPPPPL 1003
PP GI PP PG G P PG G P P LPG G P P
Sbjct: 271 PP----GIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326
Query: 1004 PGA----GIPPPPPLPGAGIPPP--------------PPLPGA-------GIPPPPPLPG 1038
G G PP PG IP P P LPG GI PP LPG
Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386
Query: 1039 AGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPL---PGA-GIPPPPPLPG 1093
PP G P PP PG G PG IP PP L PGA G+P PP G
Sbjct: 387 -----PPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAG 441
Query: 1094 AGIPPPPPLPGVGIPPPPPLPG-----------------------AGIPPPPPLPGA-GI 1129
IPP + G P PP PG GI PP PG G+
Sbjct: 442 PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGL 501
Query: 1130 PPPPP---LPG-------AGIPPPPPLPRV-GIPPPPPLPGAGIPPPPPL--PGA----- 1171
P PP PG AG P LP + G P P PG+ P L PG
Sbjct: 502 PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKG 561
Query: 1172 --GIPPPPPLPGV-GIPPPPPLPGVGIPPPPPLPGA----GIPPPPPLPGMGIPPAPAPP 1224
G P P LPG+ G P LPG +P P PG G PP PG+ P P
Sbjct: 562 ELGSPGAPGLPGLPGTPGQDGLPG--LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGP 619
Query: 1225 LPPPGTGIPPP----PLLPVSGPPLLPQV-GSSTLPTPQVCGFLPPPLPS--GLFG-LGM 1276
+ PPG G P P + V+G P P + G P + P LP G G +G+
Sbjct: 620 MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL 679
Query: 1277 NQDKGSRKQPIEPCRP 1292
D G QP P P
Sbjct: 680 PGDPGLPGQPGLPGIP 695
Score = 54.7 bits (130), Expect = 8e-07
Identities = 72/256 (28%), Positives = 91/256 (35%), Gaps = 43/256 (16%)
Query: 748 PTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSI 807
P E G P V G PG P P A GP+ + P R Q +
Sbjct: 1221 PKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ----GPPGRPGFQ--------GL 1268
Query: 808 SQPPPPPSLLWSAG-------QGQPGSQPPHSISTE-----FQTSHEHSVSSAFKNSCNI 855
P PP L + G GQPG + + Q + + K +
Sbjct: 1269 PGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGL 1328
Query: 856 PSPPPLPCTESSSSMPGL-------GMVPPPPPP-LPGMTVPTLPSTAIPQPPPLQGTEM 907
P P P + S +PG G++ PP PP LPG + ++ PP + G
Sbjct: 1329 PGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPG 1388
Query: 908 LPPPPPPLPGAGIPPPPPLPG-AGILPLPPLPGA-GIPPPPPLPGAAIPPPPPLPGA-GI 964
L P P G+P P PG G LP GA G P LPG PG G+
Sbjct: 1389 LKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQ--------PGTRGL 1440
Query: 965 PLPPPLPGAGIPPPPP 980
PP G PP PP
Sbjct: 1441 DGPPGPDGLQGPPGPP 1456
Score = 44.3 bits (103), Expect = 0.001
Identities = 49/159 (30%), Positives = 57/159 (35%), Gaps = 18/159 (11%)
Query: 255 GPSGGAGEAPGSP----------DTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEA 304
GPSG G+ PGSP D + L LP EP P P +PG
Sbjct: 1045 GPSGVPGQ-PGSPGLPGQKGDKGDPGISSIGLPGLPGP-KGEPGLPGYPGNPGIKGSVGD 1102
Query: 305 PSLPA--AQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGE-EDAFEDAPRGS 361
P LP P AK P FP PG + P G E G G
Sbjct: 1103 PGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGP 1162
Query: 362 PGEEWAPEVGEDA-PQRLGEEPEEEAQGPDAPAAASLPG 399
PGE+ P G+D P G++ E G P LPG
Sbjct: 1163 PGEKGKP--GQDGIPGPAGQKGEPGQPGFGNPGPPGLPG 1199
Score = 39.3 bits (90), Expect = 0.033
Identities = 58/241 (24%), Positives = 78/241 (32%), Gaps = 45/241 (18%)
Query: 227 QGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTE-----QALSALSDLPE 281
+G P PP V P+PG + +G G G PG P + + LP
Sbjct: 333 KGDTGPPGPPGLVIPRPGTGI-----TIGEKGNIG-LPGLPGEKGERGFPGIQGPPGLPG 386
Query: 282 SLAAEPREPQQPP------------SPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAG 329
A P PP P G+ + P L QP A P P
Sbjct: 387 PPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLD-GQPGAPGLPGPPGPAGPHIP 445
Query: 330 PGEE----AAGAPVRGAGDTDEEGEEDAFED--------------APRGSPGEEW--APE 369
P +E P GD +GE+ D P G PG P
Sbjct: 446 PSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505
Query: 370 VGEDAPQRLGEEPEEEAQGPDA-PAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSS 428
P + GE+ + A GP P PG+P +P ++T +K +L S
Sbjct: 506 GSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGS 565
Query: 429 P 429
P
Sbjct: 566 P 566
Score = 36.2 bits (82), Expect = 0.28
Identities = 47/181 (25%), Positives = 61/181 (33%), Gaps = 38/181 (20%)
Query: 236 PTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPS 295
P + QPGA L GP G AG P P +++ EP P P S
Sbjct: 421 PPGLDGQPGA-----PGLPGPPGPAG--PHIPPSDEI------------CEPGPPGPPGS 461
Query: 296 PGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEE-DAF 354
PG + + + + T P PG P G ++GE+ A
Sbjct: 462 PGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAG 521
Query: 355 EDAPRGSPGEEWAPEVGEDAPQRLGEEPEE--------------EAQGPDAPAAASLPGS 400
P+G PG AP AP G + E E P AP LPG+
Sbjct: 522 ATGPKGLPGIPGAP----GAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT 577
Query: 401 P 401
P
Sbjct: 578 P 578
Score = 33.1 bits (74), Expect = 2.4
Identities = 44/176 (25%), Positives = 60/176 (34%), Gaps = 17/176 (9%)
Query: 231 EPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEA--PGSPDTEQALSALSDLPESLAAEPR 288
+P P +S QPG L GP G G PG P + + P+
Sbjct: 989 DPGQP--GLSGQPG--------LPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQ 1038
Query: 289 EPQQPPSPGGLPVSE-APSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDE 347
+ PP P G+P +P LP Q K P ++ P + G P +
Sbjct: 1039 GVEGPPGPSGVPGQPGSPGLP-GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIK 1097
Query: 348 EGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAP 403
D G+PG + P + P G + GP P LPG P P
Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGL-PGFPGTPGPPGPKGISGP--PGNPGLPGEPGP 1150
>gi|40548415 dishevelled associated activator of morphogenesis 2 [Homo
sapiens]
Length = 1067
Score = 167 bits (423), Expect = 8e-41
Identities = 152/531 (28%), Positives = 242/531 (45%), Gaps = 78/531 (14%)
Query: 1174 PPPP--PLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTG 1231
PPPP PL LP PPPPPLP A PPPPP PPLPP G
Sbjct: 522 PPPPGGPLTLSSSMTTNDLP----PPPPPLPFACCPPPPP-----------PPLPPGGPP 566
Query: 1232 IPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCR 1291
PP PP L LP PQ P PS L +K+ +P
Sbjct: 567 TPP------GAPPCL----GMGLPLPQ------DPYPSSDVPL-------RKKRVPQPSH 603
Query: 1292 PMKPLYWTRIQLHSKRDSSTSLIWEKIEEPSI----DCHEFEELFSKTAVKERKKPISDT 1347
P+K W ++L+ +R T +W +I++ + D +FE++FS A + +K + T
Sbjct: 604 PLKSFNW--VKLNEERVPGT--VWNEIDDMQVFRILDLEDFEKMFS--AYQRHQKELGST 657
Query: 1348 ISKTKAKQVVKLLS---NKRSQAVGILMSSLHLDMKDIQHAVVNLDNSV-VDLETLQALY 1403
A + VK LS +R+Q IL+S L L ++I+ A++ +D + + L+ L
Sbjct: 658 EDIYLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKMDEQEDLAKDMLEQLL 717
Query: 1404 ENRAQSDELEKIEKHGRSSKDKENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSES 1463
+ + +++ +E+H K + + + ++FLYE+S I ++ +R+ + F+ F E
Sbjct: 718 KFIPEKSDIDLLEEH------KHEIERMARADRFLYEMSRIDHYQQRLQALFFKKKFQER 771
Query: 1464 ICSIRRKLELLQKLCETLKNGPGVMQVLGLVLAFGNYMNGGNKTRGQADGFGLDILPKLK 1523
+ + K+E + L + Q+L ++LA GN+MN G RG A GF + L K+
Sbjct: 772 LAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMNKGQ--RGGAYGFRVASLNKIA 829
Query: 1524 DVKSS-DNSRSLLSYIVSYYLRNFDEDAGKEQCLFPLPEPQDLFQASQMKFEDFQKDLRK 1582
D KSS D + SLL Y++ ++F + L LPE A+++ + +K++
Sbjct: 830 DTKSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPE------AAKVNLAELEKEVGN 883
Query: 1583 LKKDLKACEVEAGKVYQVSSKEHMQPFKENMEQFIIQAKIDQEAEENSLTETHKCFLETT 1642
L++ L+A EV + QV +E F M FI + E+ L E F +
Sbjct: 884 LRRGLRAVEVLEYQRRQV--REPSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKAL 941
Query: 1643 AYFFMKPKLGEKEVSPNAFFSIWHEFSSDFKDFWKKENKLLLQERVKEAEE 1693
+F + ++ P+ FF I+ F F + L R KE EE
Sbjct: 942 MHFGEH----DSKMQPDEFFGIFDTFLQAFSE---ARQDLEAMRRRKEEEE 985
Score = 58.9 bits (141), Expect = 4e-08
Identities = 38/94 (40%), Positives = 43/94 (45%), Gaps = 23/94 (24%)
Query: 909 PPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP 968
P PP PP PL + + LP PPPPPLP A PPPP PP
Sbjct: 518 PVSSPP------PPGGPLTLSSSMTTNDLP----PPPPPLPFACCPPPP---------PP 558
Query: 969 PLPGAGIPPPPPLP---GAGIP-PPPPLPGAGIP 998
PLP G P PP P G G+P P P P + +P
Sbjct: 559 PLPPGGPPTPPGAPPCLGMGLPLPQDPYPSSDVP 592
Score = 58.5 bits (140), Expect = 5e-08
Identities = 41/95 (43%), Positives = 45/95 (47%), Gaps = 24/95 (25%)
Query: 1105 VGIPPPP--PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGI 1162
V PPPP PL + LP PPPPPLP A PP PPPPPLP G
Sbjct: 519 VSSPPPPGGPLTLSSSMTTNDLP----PPPPPLPFACCPP---------PPPPPLPPGG- 564
Query: 1163 PPPPPLPGAGIPPPPPLPGVGIP-PPPPLPGVGIP 1196
PP PGA PP G+G+P P P P +P
Sbjct: 565 --PPTPPGA-----PPCLGMGLPLPQDPYPSSDVP 592
Score = 58.5 bits (140), Expect = 5e-08
Identities = 34/80 (42%), Positives = 40/80 (50%), Gaps = 14/80 (17%)
Query: 957 PPLPGAGIPLPPPLPGAGI-PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1015
PP PG + L + + PPPPPLP A PP PPPPPLP G P PP P
Sbjct: 522 PPPPGGPLTLSSSMTTNDLPPPPPPLPFACCPP---------PPPPPLPPGGPPTPPGAP 572
Query: 1016 ---GAGIP-PPPPLPGAGIP 1031
G G+P P P P + +P
Sbjct: 573 PCLGMGLPLPQDPYPSSDVP 592
Score = 58.2 bits (139), Expect = 7e-08
Identities = 40/100 (40%), Positives = 44/100 (44%), Gaps = 30/100 (30%)
Query: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915
P PP P T SSS +PPPPPPLP P PPPPPPL
Sbjct: 522 PPPPGGPLTLSSSMTTN--DLPPPPPPLPFACCP-------------------PPPPPPL 560
Query: 916 PGAGIPPPPPLPGAGILPLPPLPGAGIP-PPPPLPGAAIP 954
P G PP PGA PP G G+P P P P + +P
Sbjct: 561 PPGG---PPTPPGA-----PPCLGMGLPLPQDPYPSSDVP 592
Score = 58.2 bits (139), Expect = 7e-08
Identities = 37/84 (44%), Positives = 41/84 (48%), Gaps = 19/84 (22%)
Query: 987 PPPP--PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1044
PPPP PL + LP PPPPPLP A PP PPPPPLP G P P
Sbjct: 522 PPPPGGPLTLSSSMTTNDLP----PPPPPLPFACCPP---------PPPPPLPPGGPPTP 568
Query: 1045 PPLP---GAGIP-PPPPLPGAGIP 1064
P P G G+P P P P + +P
Sbjct: 569 PGAPPCLGMGLPLPQDPYPSSDVP 592
Score = 58.2 bits (139), Expect = 7e-08
Identities = 37/84 (44%), Positives = 41/84 (48%), Gaps = 19/84 (22%)
Query: 1020 PPPP--PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1077
PPPP PL + LP PPPPPLP A PP PPPPPLP G P P
Sbjct: 522 PPPPGGPLTLSSSMTTNDLP----PPPPPLPFACCPP---------PPPPPLPPGGPPTP 568
Query: 1078 PPLP---GAGIP-PPPPLPGAGIP 1097
P P G G+P P P P + +P
Sbjct: 569 PGAPPCLGMGLPLPQDPYPSSDVP 592
Score = 57.4 bits (137), Expect = 1e-07
Identities = 43/105 (40%), Positives = 49/105 (46%), Gaps = 28/105 (26%)
Query: 1053 PPPP--PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPP 1110
PPPP PL + LP PPPPPLP A PP PPPPPLP G P
Sbjct: 522 PPPPGGPLTLSSSMTTNDLP----PPPPPLPFACCPP---------PPPPPLPPGG---P 565
Query: 1111 PPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIPPPPPLPRVGIPPP 1154
P PGA PP G G+P P P P + + PL + +P P
Sbjct: 566 PTPPGA-----PPCLGMGLPLPQDPYPSSDV----PLRKKRVPQP 601
Score = 54.7 bits (130), Expect = 8e-07
Identities = 34/88 (38%), Positives = 40/88 (45%), Gaps = 19/88 (21%)
Query: 1089 PPLPGAGIPPPPPLPGVGI-PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1147
PP PG + + + PPPPPLP A PP PPPPPLP G P P
Sbjct: 522 PPPPGGPLTLSSSMTTNDLPPPPPPLPFACCPP---------PPPPPLPPGGPPTP---- 568
Query: 1148 RVGIPPPPPLPGAGIP-PPPPLPGAGIP 1174
P PP G G+P P P P + +P
Sbjct: 569 ----PGAPPCLGMGLPLPQDPYPSSDVP 592
Score = 50.8 bits (120), Expect = 1e-05
Identities = 35/95 (36%), Positives = 42/95 (44%), Gaps = 23/95 (24%)
Query: 930 GILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPP 989
G + PP PG + + +PPPPP PLP A PPP PP
Sbjct: 517 GPVSSPPPPGGPLTLSSSMTTNDLPPPPP----------PLPFACCPPP---------PP 557
Query: 990 PPLPGAGIPPPPPLP---GAGIP-PPPPLPGAGIP 1020
PPLP G P PP P G G+P P P P + +P
Sbjct: 558 PPLPPGGPPTPPGAPPCLGMGLPLPQDPYPSSDVP 592
Score = 39.7 bits (91), Expect = 0.026
Identities = 34/116 (29%), Positives = 39/116 (33%), Gaps = 22/116 (18%)
Query: 800 SHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPP 859
S T +S PPPP L + PP F C P PP
Sbjct: 512 SELSTGPVSSPPPPGGPLTLSSSMTTNDLPPPPPPLPFAC-------------CPPPPPP 558
Query: 860 PLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915
PLP PG PP PP GM +P LP P + +P P PL
Sbjct: 559 PLP--------PGGPPTPPGAPPCLGMGLP-LPQDPYPSSDVPLRKKRVPQPSHPL 605
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 167 bits (422), Expect = 1e-40
Identities = 146/413 (35%), Positives = 148/413 (35%), Gaps = 61/413 (14%)
Query: 859 PPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEML--PPPPPPLP 916
P L + P G P PP PG PQ PP QG PPPPP
Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGK----------PQGPPPQGGNQPQGPPPPP--- 75
Query: 917 GAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIP 976
G P PP G PP PG PPP + P PP G P PP G P
Sbjct: 76 --GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP----GKPQGPPPQGGNQP 129
Query: 977 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP--------PLPGAGIPPPPPLPGA 1028
PP P G P PP G P PP PG PPP G P PP G
Sbjct: 130 QGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGG 188
Query: 1029 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP----PLPGAGIPP-----PPP 1079
P PP P G P PP G P PP PG PPP A PP PPP
Sbjct: 189 NQPQGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPP 247
Query: 1080 LPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPP--------PLPGAGIPP 1131
G PPP PG P PP G P PP PG PPP G P
Sbjct: 248 QGGNQPQGPPPPPGK--PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQ 305
Query: 1132 PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPP--------PLPGVG 1183
PP G P PP P G P PP G P PP PG PPP G
Sbjct: 306 GPPPQGGNQPQGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPG 364
Query: 1184 IPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPP 1236
P PP P PP P G P P P G P PP PP G PP
Sbjct: 365 KPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQP--QGPPRPPQGGRPSRPP 415
Score = 146 bits (368), Expect = 2e-34
Identities = 142/398 (35%), Positives = 146/398 (36%), Gaps = 70/398 (17%)
Query: 940 AGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 999
AG P P G P PP P G P PP G P PP P G P PP G P
Sbjct: 33 AGNPQGAPPQGGNKPQGPPSP-PGKPQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGNKPQ 90
Query: 1000 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1059
PP PG PPP + P PP G P PP G P PP PPP
Sbjct: 91 GPPPPGKPQGPPPQGDKSRSPRSPP----GKPQGPPPQGGNQPQGPP-------PPP--- 136
Query: 1060 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPP--------PLPGAGIPPPPPLPGVGIPPPP 1111
G P PP G P PP PG PPP G P PP G P P
Sbjct: 137 --GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGP 194
Query: 1112 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP--------PLPRVGIPPPPPLPGAGIP 1163
P P G P PP G P PP PG PPP G P PP G P
Sbjct: 195 P-PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQP 253
Query: 1164 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPP----PLPGAGIPP-----PPPLPG 1214
PP P G P PP G P PP PG PPP + PP PPP G
Sbjct: 254 QGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGG 312
Query: 1215 ---MGIPPAPAPPLPPPGTG-----IPPPPLLPVSGPPLLPQVGSSTLPT---------- 1256
G PP P P PP G PPPP P GPP PQ GS +
Sbjct: 313 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP-QGPP--PQGGSKSRSARSPPGKPQGP 369
Query: 1257 PQVCGFLP--PPLPSGLFGLGMNQDKGSRKQPIEPCRP 1292
PQ G P PP P+G G QP P RP
Sbjct: 370 PQQEGNNPQGPPPPAG--GNPQQPQAPPAGQPQGPPRP 405
Score = 135 bits (340), Expect = 3e-31
Identities = 129/400 (32%), Positives = 138/400 (34%), Gaps = 48/400 (12%)
Query: 758 PPVDG-LPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQP--PPPP 814
PP G P PP PPG GP + ++ P P Q ++P PPPP
Sbjct: 40 PPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPG----KPQGPPPQGGNKPQGPPPP 95
Query: 815 SLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLG 874
G+P PP + S N P PP P + P G
Sbjct: 96 --------GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 147
Query: 875 MVP--PPPPPLPGMTVPT---------LPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPP 923
P PPPP P P P PPP G + PPPPP G P
Sbjct: 148 NKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPP----GKPQG 203
Query: 924 PPLPGAGILPLPPLPGAGIPPPPP----LPGAAIPP-----PPPLPGAGIPLPPPLPGAG 974
PP G PP PG PPP A PP PPP G PPP PG
Sbjct: 204 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGK- 262
Query: 975 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1034
P PP G P PP PG P P P G G P PP G P P
Sbjct: 263 -PQGPPPQGGNKPQGPPPPG---KPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGP 318
Query: 1035 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1094
P P G P PP G P PP PG P P P G G P PP
Sbjct: 319 P-PPPGKPQGPPPQGGNKPQGPPPPG---KPQGPPPQGGSKSRSARSPPGKPQGPPQQEG 374
Query: 1095 GIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1134
P PP P G P P P AG P PP P G P P
Sbjct: 375 NNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 414
Score = 126 bits (316), Expect = 2e-28
Identities = 125/395 (31%), Positives = 131/395 (33%), Gaps = 76/395 (19%)
Query: 745 QTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPT 804
Q P G PP G + P PPG GP + S P + P
Sbjct: 69 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGK-----PQGPPP 123
Query: 805 QSISQP--PPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLP 862
Q +QP PPPP G+P PP N P PP P
Sbjct: 124 QGGNQPQGPPPP-------PGKPQGPPPQG-----------------GNKPQGPPPPGKP 159
Query: 863 ---------CTESSSSMPGLGMVPPP--------PPPLPGMTVPTLPSTAIPQPPPLQGT 905
+ SS S PG PPP PPP PG PQ PP QG
Sbjct: 160 QGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGK----------PQGPPPQGG 209
Query: 906 EMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIP 965
PPPP G P PP G P PPP G PPP PG P
Sbjct: 210 NKPQGPPPP----GKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGK--P 263
Query: 966 LPPPLPGAGIPPPPPLPGAGIPPPP--------PLPGAGIPPPPPLPGAGIPPPPPLPGA 1017
PP G P PP PG PPP G P PP G P PP P
Sbjct: 264 QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPP-PPP 322
Query: 1018 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1077
G P PP G P PP PG P P P G G P PP P
Sbjct: 323 GKPQGPPPQGGNKPQGPPPPG---KPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQG 379
Query: 1078 PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP 1112
PP P G P P P AG P PP P G P P
Sbjct: 380 PPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 414
Score = 79.3 bits (194), Expect = 3e-14
Identities = 86/287 (29%), Positives = 95/287 (33%), Gaps = 30/287 (10%)
Query: 745 QTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPT 804
Q P G PP G + P PPG GP + ++ SP
Sbjct: 130 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGN 189
Query: 805 QSISQPPPPPSLLWSAGQG--QPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLP 862
Q PPPP QG +P PP ++ SA PPP
Sbjct: 190 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQG 249
Query: 863 CTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEML---------PPPPP 913
+ P G P PPP G P PQ PP QG P PP
Sbjct: 250 GNQPQGPPPPPGK-PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPP 308
Query: 914 PLPG---AGIPPPP-----PLPGAGILPLPPLPGAGIPPPPPLPGA----AIPPP----- 956
P G G PPPP P P G P P P PPP G+ A PP
Sbjct: 309 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQG 368
Query: 957 PPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPP 1002
PP P PP P G P P P AG P PP P G P PP
Sbjct: 369 PPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415
Score = 47.4 bits (111), Expect = 1e-04
Identities = 55/224 (24%), Positives = 73/224 (32%), Gaps = 29/224 (12%)
Query: 227 QGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGG-AGEAPGSPDTEQALSALSDLPESLAA 285
QG +P PP P PG G P GG + P P Q D S +
Sbjct: 63 QGGNQPQGPP----PPPGKPQGPP-----PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 113
Query: 286 EPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDT 345
P +PQ PP GG + P P P P P+ G + P + G
Sbjct: 114 PPGKPQGPPPQGG-------NQPQGPPPPPGKPQG---PPPQGGNKPQGPPPPGKPQGPP 163
Query: 346 DEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQ 405
+ + +P G P + P G + PQ P + QGP G P P +
Sbjct: 164 PQGDNKSRSSRSPPGKP--QGPPPQGGNQPQG-PPPPPGKPQGPPPQGGNKPQGPPPPGK 220
Query: 406 RCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEP 449
P P ++ SP P P Q + P P
Sbjct: 221 ------PQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPP 258
Score = 46.2 bits (108), Expect = 3e-04
Identities = 51/189 (26%), Positives = 65/189 (34%), Gaps = 36/189 (19%)
Query: 227 QGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGG--------AGEAPGSPDTEQALSALSD 278
QG +P PP P PG G P GG G+ G P + S S
Sbjct: 248 QGGNQPQGPP----PPPGKPQGPP-----PQGGNKPQGPPPPGKPQGPPPQGGSKSRSSR 298
Query: 279 LPESLAAEP-----REPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEE 333
P P +PQ PP P G P P +P P P P+ G
Sbjct: 299 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ-GGNKPQGPPPPGKPQGPPPQGGSKSR 357
Query: 334 AAGAPV-RGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAP 392
+A +P + G +EG P+G P P G + PQ+ P + QGP P
Sbjct: 358 SARSPPGKPQGPPQQEGNN------PQGPP-----PPAGGN-PQQPQAPPAGQPQGPPRP 405
Query: 393 AAASLPGSP 401
P P
Sbjct: 406 PQGGRPSRP 414
Score = 41.6 bits (96), Expect = 0.007
Identities = 47/186 (25%), Positives = 65/186 (34%), Gaps = 16/186 (8%)
Query: 227 QGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAE 286
QG +P PP PQ G ++ S A PG P + P+
Sbjct: 207 QGGNKPQGPPPPGKPQGPPPQGDNK-----SQSARSPPGKPQGPPPQGG--NQPQGPPPP 259
Query: 287 PREPQQPP-----SPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRG 341
P +PQ PP P G P P P Q +K S SS + P GP + P
Sbjct: 260 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSK-SRSSRSPPGKPQGPPPQGGNQPQGP 318
Query: 342 AGDTDE-EGEEDAFEDAPRGSP--GEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLP 398
+ +G + P+G P G+ P + R P + QGP +
Sbjct: 319 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQ 378
Query: 399 GSPAPS 404
G P P+
Sbjct: 379 GPPPPA 384
Score = 41.2 bits (95), Expect = 0.009
Identities = 43/181 (23%), Positives = 63/181 (34%), Gaps = 11/181 (6%)
Query: 270 EQALSALSDLPESLAAEP-REPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEA 328
E++ S ++ P+ + +PQ PPSP G P P P P P+
Sbjct: 26 EESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 85
Query: 329 GPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQG 388
G + P + G +G++ +P G P + P G + PQ P + QG
Sbjct: 86 GNKPQGPPPPGKPQG-PPPQGDKSRSPRSPPGKP--QGPPPQGGNQPQG-PPPPPGKPQG 141
Query: 389 PDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPE 448
P G P P + P P +R SP P P Q + P
Sbjct: 142 PPPQGGNKPQGPPPPGK------PQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPP 195
Query: 449 P 449
P
Sbjct: 196 P 196
Score = 40.0 bits (92), Expect = 0.020
Identities = 46/198 (23%), Positives = 64/198 (32%), Gaps = 24/198 (12%)
Query: 227 QGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAE 286
QG +P PP PQ G ++ S + PG P + P+
Sbjct: 145 QGGNKPQGPPPPGKPQGPPPQGDNK-----SRSSRSPPGKPQGPPPQGG--NQPQGPPPP 197
Query: 287 PREPQQPPSPGGLPVS--EAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGD 344
P +PQ PP GG P P P D+ S +A P + G P +G
Sbjct: 198 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSA-----RSPPGKPQGPPPQGGNQ 252
Query: 345 TD--------EEGEEDAFEDAPRGSP--GEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAA 394
+G + P+G P G+ P + R P + QGP
Sbjct: 253 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGG 312
Query: 395 ASLPGSPAPSQRCFKPYP 412
G P P + P P
Sbjct: 313 NQPQGPPPPPGKPQGPPP 330
>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
sapiens]
Length = 1685
Score = 166 bits (421), Expect = 1e-40
Identities = 223/693 (32%), Positives = 259/693 (37%), Gaps = 200/693 (28%)
Query: 750 EEGGVLTLPPVDGLPGRP--------PCPPGAESGPQTKFCSEISLIVSPRRISVQLDSH 801
+ G +T P GLPG P P PG P P + +
Sbjct: 654 DPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGL-----------PGIPGSKGEPG 702
Query: 802 QPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPP-- 859
P + PP P G PG PP + T + E P PP
Sbjct: 703 IPGIGLPGPPGPKGF-----PGIPG--PPGAPGTPGRIGLE-----------GPPGPPGF 744
Query: 860 PLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPS-----TAIPQPPPLQGTEMLPPP--- 911
P P E ++PG PP PP LPG P P PP G + LP P
Sbjct: 745 PGPKGEPGFALPG----PPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGD 800
Query: 912 -----------PPPLPGAGI---PPPPPLPG-AGILPLPPLPGAGIPPPPPLPGAAIPPP 956
PP LPG G+ P PP +PG G L +PG P P PG +P P
Sbjct: 801 VGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGP--PGLDVPGP 858
Query: 957 ------PPLPGAGIPLPPP----LPG----AGIP----------PPPPLPGAGIPPPPPL 992
P +PGA P+ PP LPG +G P PP P GIP +
Sbjct: 859 PGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGV 918
Query: 993 PGA----GIPPPPPLPG----AGIPPPPPLPGAGIPPPPPLPGA----GIPPPPPLPGA- 1039
PG G+ P LPG G P LPG P P L G+ G P P +PG
Sbjct: 919 PGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVS 978
Query: 1040 ------GIPPPPPLPG----AGIPPP------PPLPG-AGIPPPPPLPGA----GIP--- 1075
G+P P PG G+P P P LPG G+ PP L G G P
Sbjct: 979 GPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQ 1038
Query: 1076 ----PPPPLPGAGIPPPPPLPG---------------AGIPPPPPLPGV-GIPPPPPLPG 1115
PP P G P P LPG G+P P PG+ G P P + G
Sbjct: 1039 GVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKG 1098
Query: 1116 A-GIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIP-PPPPLPGAG 1172
+ G P P LPG G P LPG P PP P+ GI PP P G+P P P+ G G
Sbjct: 1099 SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK-GISGPPGNP--GLPGEPGPVGGGG 1155
Query: 1173 IPPPPPLPGV-------GIPPP------PPLPGVGIPPPPPLPG----------AGIPPP 1209
P P PG GIP P P PG G P PP LPG GIP
Sbjct: 1156 HPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGN 1215
Query: 1210 PPLPG-------MGIPPAPAPPLPP--PGTGIPPPPLLP-VSGPPLLPQVGSSTLPTPQV 1259
P LPG G P PP PP PG + P P GPP G LP P+
Sbjct: 1216 PGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP-----GRPGLPGPEG 1270
Query: 1260 CGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRP 1292
PP LP G+ +KG+ QP P P
Sbjct: 1271 ----PPGLPG---NGGIKGEKGNPGQPGLPGLP 1296
Score = 163 bits (412), Expect = 2e-39
Identities = 175/492 (35%), Positives = 198/492 (40%), Gaps = 92/492 (18%)
Query: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMT-VPTLPST-AIPQPPPLQGTEMLPPPPP 913
P P LP PG G PP P G+ V P IP P G + P P
Sbjct: 608 PGLPGLPGNIGPMGPPGFG--PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKP 665
Query: 914 PLPG-------AGIPPPPPLPGAGILP-------LPPLPGAGIPPPPPLPG-AAIPPPPP 958
LPG G+P P LPG LP P +PG G+P PP G IP PP
Sbjct: 666 GLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG 725
Query: 959 LPGA-------GIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPG----------AGIPPPP 1001
PG G P PP PG P LPG P PP LPG G P PP
Sbjct: 726 APGTPGRIGLEGPPGPPGFPGPKGEPGFALPGP--PGPPGLPGFKGALGPKGDRGFPGPP 783
Query: 1002 PLPGA----GIPPPPPLPGAGIPP----PPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GI 1052
PG G+P P G P PP LPG G+ PP P GIP P PG GI
Sbjct: 784 GPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPP--GIPGPIGQPGLHGI 841
Query: 1053 P---PPPPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPLPG----AGIPPPPPLPG 1104
P P PG +P PP G+ P P PG G P P LPG +G P G
Sbjct: 842 PGEKGDPGPPGLDVPGPPGERGS--PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMG 899
Query: 1105 VGIPPPPPLPGAGIPPPPPLPGA----GIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGA 1160
+ PP PP P GIP +PG G+ P LPG P G P LPG
Sbjct: 900 MMGPPGPPGP-LGIPGRSGVPGLKGDDGLQGQPGLPG-------PTGEKGSKGEPGLPGP 951
Query: 1161 GIPPPPPLPGA-GIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGM-GIP 1218
P P L G+ G P LPG+ PGV P G+P P PG+ G P
Sbjct: 952 PGPMDPNLLGSKGEKGEPGLPGI--------PGVS----GPKGYQGLPGDPGQPGLSGQP 999
Query: 1219 PAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGL---- 1274
P PP P G+P P L + P L +G P PQ G PP PSG+ G
Sbjct: 1000 GLPGPPGPKGNPGLPGQPGL-IGPPGLKGTIGDMGFPGPQ--GVEGPPGPSGVPGQPGSP 1056
Query: 1275 GMNQDKGSRKQP 1286
G+ KG + P
Sbjct: 1057 GLPGQKGDKGDP 1068
Score = 162 bits (410), Expect = 3e-39
Identities = 223/705 (31%), Positives = 262/705 (37%), Gaps = 219/705 (31%)
Query: 747 SPTEEGGVLTLPPVDGLPGRPPCP--PGAESGPQTKFCSEISLIVSPRRISVQLDSHQPT 804
+P +G V LP GLPG+P P PG++ P P
Sbjct: 670 NPGRDGDV-GLPGDPGLPGQPGLPGIPGSKGEPGI-----------------------PG 705
Query: 805 QSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPP--PLP 862
+ PP P G PG PP + T + E P PP P P
Sbjct: 706 IGLPGPPGPKGF-----PGIPG--PPGAPGTPGRIGLEGP-----------PGPPGFPGP 747
Query: 863 CTESSSSMPGLGMVPPPPPPLPGMTVPTLPS-----TAIPQPPPLQGTEMLPPP------ 911
E ++PG PP PP LPG P P PP G + LP P
Sbjct: 748 KGEPGFALPG----PPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGP 803
Query: 912 --------PPPLPGAGI---PPPPPLPGA-GILPLPPLPGAGIPPPPPLPGAAIPPPPP- 958
PP LPG G+ P PP +PG G L +PG P PP G +P PP
Sbjct: 804 NGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPP--GLDVPGPPGE 861
Query: 959 -----LPGAGIPLPPP----LPG----AGIP----------PPPPLPGAGIPPPPPLPGA 995
+PGA P+ PP LPG +G P PP P GIP +PG
Sbjct: 862 RGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGL 921
Query: 996 ----GIPPPPPLPGA----GIPPPPPLPGAGIPPPPPLPGA----GIPPPPPLPGA---- 1039
G+ P LPG G P LPG P P L G+ G P P +PG
Sbjct: 922 KGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981
Query: 1040 ---GIPPPPPLPGA----GIPPPPP------LPGA-GIPPPPPLPGA----GIPPP---- 1077
G+P P PG G+P PP LPG G+ PP L G G P P
Sbjct: 982 GYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041
Query: 1078 -PPLPGA--GIPPPPPLPGA---------------GIPPPPPLPGV-GIPPPPPLPGA-- 1116
PP P G P P LPG G+P P PG+ G P P + G+
Sbjct: 1042 GPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVG 1101
Query: 1117 --GIPPPPPLPGA-GIPPPPPLPGAGIPPPP-----PLPRVGIPPPP-PLPGAGIPPPPP 1167
G+P P PGA G P P PG PP P P G+P P P+ G G P P
Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPG 1161
Query: 1168 LPGA-------GIPPP------PPLPGVGIPPPPPLPGV----------GIPPPPPLPGA 1204
PG GIP P P PG G P PP LPG+ GIP P LPG
Sbjct: 1162 PPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGP 1221
Query: 1205 ----------GI-----PPPPPLPGMGIPPA-PAPPLPPPGTGIPPPPLLPVSGPPLLPQ 1248
G+ PP P P + P P P PP G+P P GPP LP
Sbjct: 1222 KGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGP-----EGPPGLPG 1276
Query: 1249 VGSSTLPTPQVCGFLPPPLPSGLFGL-GMNQDKGSRKQPIEPCRP 1292
G + G P GL GL G+ D+G P RP
Sbjct: 1277 NGG-------IKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP 1314
Score = 154 bits (388), Expect = 9e-37
Identities = 211/636 (33%), Positives = 238/636 (37%), Gaps = 156/636 (24%)
Query: 748 PTEEG--GVLTLPPVDGLPGRPPCP--PGAESGPQTKFCSEISLIVSPRRISVQLDSHQP 803
P E G G+ P G PG P P GA P TK E+ ++ P
Sbjct: 859 PGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTK--GEMGMMGPPG----------- 905
Query: 804 TQSISQPPPPPSLLWSAG----------QGQPGSQPPHSISTEFQTSHEHSVSSAFKNSC 853
PP P + +G QGQPG P T + S
Sbjct: 906 ------PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP--------TGEKGSKGEPGLPGP 951
Query: 854 NIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPT----LPSTAIPQPPPLQGTEMLP 909
P P L ++ PGL P +PG++ P LP P P L G LP
Sbjct: 952 PGPMDPNLLGSKGEKGEPGL-------PGIPGVSGPKGYQGLPGD--PGQPGLSGQPGLP 1002
Query: 910 PPPPPLPGAGIPPPPPLPGA-------GILPLPPLPGAGIPPPPP-LPGAAIPPPPPLPG 961
PP P G+P P L G G + P G PP P +PG P P LPG
Sbjct: 1003 GPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQ--PGSPGLPG 1060
Query: 962 A------------GIP-LPPPLPGAGIPPPPPLPG----AGIPPPPPLPGA-GIPPPPPL 1003
G+P LP P G+P P PG G P P LPG G P L
Sbjct: 1061 QKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGL 1120
Query: 1004 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGAGIPPPPPLPGA-GIPPPPPLPG- 1060
PG P PP P GI PP PG +P P P+ G G P P PG G P +PG
Sbjct: 1121 PGFPGTPGPPGP-KGISGPPGNPG--LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGP 1177
Query: 1061 AGIPPPPPLPGAGIPPPPPLPGA----------GIPPPPPLPGA-GIPPPPPLPGVGIPP 1109
AG P PG G P PP LPG GIP P LPG G P PGV PP
Sbjct: 1178 AGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPP 1237
Query: 1110 PPP-LPGAGIPPPPPLPGAGIPPPPP-LPGAGIPPPPP-----LPRVGIPPPPPLPGA-- 1160
PP PG + P PG PP P LPG PP P G P P LPG
Sbjct: 1238 GPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1297
Query: 1161 --GIPPPPPLPGA-------GIPPPPPLPGV----GIPPPPPLPG----------VGIPP 1197
G PP L G G+ P LPGV G+ P +PG +G P
Sbjct: 1298 LKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPG 1357
Query: 1198 PPPLPG-----------AGIPPPPPLPGMGIPPAPAPPLPPPG-TGIPPPPLLPVSGPPL 1245
PP LPG AG P P PG+ P P P PG TG P P G
Sbjct: 1358 PPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDP-----GRNG 1412
Query: 1246 LP-------QVGSSTLP-TPQVCGFLPPPLPSGLFG 1273
LP + G LP P G PP P GL G
Sbjct: 1413 LPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQG 1448
Score = 148 bits (373), Expect = 5e-35
Identities = 194/577 (33%), Positives = 222/577 (38%), Gaps = 89/577 (15%)
Query: 753 GVLTLPPVDGLPGRPPCP-PGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPP 811
GV L DGL G+P P P E G + E L P + L + + P
Sbjct: 917 GVPGLKGDDGLQGQPGLPGPTGEKGSK----GEPGLPGPPGPMDPNLLGSKGEKGEPGLP 972
Query: 812 PPPSLLWSAG-QGQPGS--QPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSS 868
P + G QG PG QP S + + PP L T
Sbjct: 973 GIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDM 1032
Query: 869 SMPGLGMVPPPPPP--LPGMT-VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPP 925
PG V PP P +PG P LP + P + LP P P G+P P
Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPG 1092
Query: 926 LPG----AGILPLPPLPGA-GIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPP- 979
PG G LP LPG G P LPG P PP P GI PP PG +P P
Sbjct: 1093 NPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGP-KGISGPPGNPG--LPGEPG 1149
Query: 980 PLPGAGIPPPPPLPGA-GIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGA--------- 1028
P+ G G P P PG G P +PG AG P PG G P PP LPG
Sbjct: 1150 PVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL 1209
Query: 1029 -GIPPPPPLPGA-GIPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGAGIPPPPP-LPGAG 1084
GIP P LPG G P PG PP PP PG + P PG PP P LPG
Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPE 1269
Query: 1085 IPPPPPLPGA-----GIPPPPPLPGV----GIPPPPPLPGA-------GIPPPPPLPGA- 1127
PP P G G P P LPG+ G PP L G G+ P LPG
Sbjct: 1270 GPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVP 1329
Query: 1128 ---GIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGA--------GIPPPPPLPGAGIPPP 1176
G+ P +PG+ P P +G P PP LPG G PP GIP
Sbjct: 1330 GFPGMKGPSGVPGSAGPEGEP-GLIGPPGPPGLPGPSGQSIIIKGDAGPP-----GIPGQ 1383
Query: 1177 PPLPGVGIPPPPP-LPGVGIPPPPP----LPG----------AGIPPPPPLPGMGIPPAP 1221
P L G+ P P LPG PP P LPG G+P P G+ PP P
Sbjct: 1384 PGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGP 1443
Query: 1222 APPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQ 1258
PPG PP V+ L+ + S T PQ
Sbjct: 1444 DGLQGPPG----PPGTSSVAHGFLITR-HSQTTDAPQ 1475
Score = 139 bits (349), Expect = 3e-32
Identities = 211/676 (31%), Positives = 240/676 (35%), Gaps = 160/676 (23%)
Query: 751 EGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQP 810
E G P ++G PG P P G E P + I P + I P
Sbjct: 46 EKGERGFPGLEGHPGLPGFP-GPEGPPGPRGQKGDDGIPGP----------PGPKGIRGP 94
Query: 811 PPPPSLLWSAG----QGQPGSQPPHSISTEFQTSHEHSV--SSAFKNSCNIPSPPPLPCT 864
P P + G G G+ P I T E S F P PP +P
Sbjct: 95 PGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGM 154
Query: 865 ESS------SSMPGLGMVP--PPPPPLPGMTVPT-LPST-AIPQPPPLQGTEMLPPPPPP 914
+ SS+PG P P PP + G+ PT +P P PP L G PP PP
Sbjct: 155 KGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG----PPGPPG 210
Query: 915 LPGA------------------GIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPP 956
LPG G+ PP PG P+ LPG PP
Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPG 270
Query: 957 PPLPGAGIPLPPPLPGA--------GIPPPPPLPGA----GIPPPPPLPG-AGIPPPPPL 1003
PP GI PP PG G P PG G P P LPG G P P
Sbjct: 271 PP----GIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326
Query: 1004 PGA----GIPPPPPLPGAGIPPP--------------PPLPGA-------GIPPPPPLPG 1038
G G PP PG IP P P LPG GI PP LPG
Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386
Query: 1039 AGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPL---PGA-GIPPPPPLPG 1093
PP G P PP PG G PG IP PP L PGA G+P PP G
Sbjct: 387 -----PPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAG 441
Query: 1094 AGIPPPPPLPGVGIPPPPPLPG-----------------------AGIPPPPPLPGA-GI 1129
IPP + G P PP PG GI PP PG G+
Sbjct: 442 PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGL 501
Query: 1130 PPPPP---LPG-------AGIPPPPPLPRV-GIPPPPPLPGAGIPPPPPL--PGA----- 1171
P PP PG AG P LP + G P P PG+ P L PG
Sbjct: 502 PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKG 561
Query: 1172 --GIPPPPPLPGV-GIPPPPPLPGVGIPPPPPLPGA----GIPPPPPLPGMGIPPAPAPP 1224
G P P LPG+ G P LPG +P P PG G PP PG+ P P
Sbjct: 562 ELGSPGAPGLPGLPGTPGQDGLPG--LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGP 619
Query: 1225 LPPPGTGIPPP----PLLPVSGPPLLPQV-GSSTLPTPQVCGFLPPPLPS--GLFG-LGM 1276
+ PPG G P P + V+G P P + G P + P LP G G +G+
Sbjct: 620 MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL 679
Query: 1277 NQDKGSRKQPIEPCRP 1292
D G QP P P
Sbjct: 680 PGDPGLPGQPGLPGIP 695
Score = 53.1 bits (126), Expect = 2e-06
Identities = 71/256 (27%), Positives = 90/256 (35%), Gaps = 46/256 (17%)
Query: 748 PTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSI 807
P E G P V G PG P P A GP+ Q +P +
Sbjct: 1221 PKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGN-------------PGPQGPPGRP--GL 1265
Query: 808 SQPPPPPSLLWSAG-------QGQPGSQPPHSISTE-----FQTSHEHSVSSAFKNSCNI 855
P PP L + G GQPG + + Q + + K +
Sbjct: 1266 PGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGL 1325
Query: 856 PSPPPLPCTESSSSMPGL-------GMVPPPPPP-LPGMTVPTLPSTAIPQPPPLQGTEM 907
P P P + S +PG G++ PP PP LPG + ++ PP + G
Sbjct: 1326 PGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPG 1385
Query: 908 LPPPPPPLPGAGIPPPPPLPG-AGILPLPPLPGA-GIPPPPPLPGAAIPPPPPLPGA-GI 964
L P P G+P P PG G LP GA G P LPG PG G+
Sbjct: 1386 LKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQ--------PGTRGL 1437
Query: 965 PLPPPLPGAGIPPPPP 980
PP G PP PP
Sbjct: 1438 DGPPGPDGLQGPPGPP 1453
Score = 44.3 bits (103), Expect = 0.001
Identities = 49/159 (30%), Positives = 57/159 (35%), Gaps = 18/159 (11%)
Query: 255 GPSGGAGEAPGSP----------DTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEA 304
GPSG G+ PGSP D + L LP EP P P +PG
Sbjct: 1045 GPSGVPGQ-PGSPGLPGQKGDKGDPGISSIGLPGLPGP-KGEPGLPGYPGNPGIKGSVGD 1102
Query: 305 PSLPA--AQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGE-EDAFEDAPRGS 361
P LP P AK P FP PG + P G E G G
Sbjct: 1103 PGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGP 1162
Query: 362 PGEEWAPEVGEDA-PQRLGEEPEEEAQGPDAPAAASLPG 399
PGE+ P G+D P G++ E G P LPG
Sbjct: 1163 PGEKGKP--GQDGIPGPAGQKGEPGQPGFGNPGPPGLPG 1199
Score = 39.3 bits (90), Expect = 0.033
Identities = 58/241 (24%), Positives = 78/241 (32%), Gaps = 45/241 (18%)
Query: 227 QGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTE-----QALSALSDLPE 281
+G P PP V P+PG + +G G G PG P + + LP
Sbjct: 333 KGDTGPPGPPGLVIPRPGTGI-----TIGEKGNIG-LPGLPGEKGERGFPGIQGPPGLPG 386
Query: 282 SLAAEPREPQQPP------------SPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAG 329
A P PP P G+ + P L QP A P P
Sbjct: 387 PPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLD-GQPGAPGLPGPPGPAGPHIP 445
Query: 330 PGEE----AAGAPVRGAGDTDEEGEEDAFED--------------APRGSPGEEW--APE 369
P +E P GD +GE+ D P G PG P
Sbjct: 446 PSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505
Query: 370 VGEDAPQRLGEEPEEEAQGPDA-PAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSS 428
P + GE+ + A GP P PG+P +P ++T +K +L S
Sbjct: 506 GSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGS 565
Query: 429 P 429
P
Sbjct: 566 P 566
Score = 36.2 bits (82), Expect = 0.28
Identities = 47/181 (25%), Positives = 61/181 (33%), Gaps = 38/181 (20%)
Query: 236 PTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPS 295
P + QPGA L GP G AG P P +++ EP P P S
Sbjct: 421 PPGLDGQPGA-----PGLPGPPGPAG--PHIPPSDEI------------CEPGPPGPPGS 461
Query: 296 PGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEE-DAF 354
PG + + + + T P PG P G ++GE+ A
Sbjct: 462 PGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAG 521
Query: 355 EDAPRGSPGEEWAPEVGEDAPQRLGEEPEE--------------EAQGPDAPAAASLPGS 400
P+G PG AP AP G + E E P AP LPG+
Sbjct: 522 ATGPKGLPGIPGAP----GAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT 577
Query: 401 P 401
P
Sbjct: 578 P 578
Score = 33.1 bits (74), Expect = 2.4
Identities = 44/176 (25%), Positives = 60/176 (34%), Gaps = 17/176 (9%)
Query: 231 EPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEA--PGSPDTEQALSALSDLPESLAAEPR 288
+P P +S QPG L GP G G PG P + + P+
Sbjct: 989 DPGQP--GLSGQPG--------LPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQ 1038
Query: 289 EPQQPPSPGGLPVSE-APSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDE 347
+ PP P G+P +P LP Q K P ++ P + G P +
Sbjct: 1039 GVEGPPGPSGVPGQPGSPGLP-GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIK 1097
Query: 348 EGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAP 403
D G+PG + P + P G + GP P LPG P P
Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGL-PGFPGTPGPPGPKGISGP--PGNPGLPGEPGP 1150
Score = 33.1 bits (74), Expect = 2.4
Identities = 32/125 (25%), Positives = 41/125 (32%), Gaps = 31/125 (24%)
Query: 291 QQPPSPGGLPVSEAPSL--PAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEE 348
Q PP P G P P+L P P + P P PE PG G ++G
Sbjct: 1234 QGPPGPPGSP---GPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGG-IKG------- 1282
Query: 349 GEEDAFEDAPRGSPGEEWAPEV----GEDAPQRLGEEPEEEAQG-----PDAPAAASLPG 399
+G+PG+ P + G+ P L P P P PG
Sbjct: 1283 ---------EKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG 1333
Query: 400 SPAPS 404
PS
Sbjct: 1334 MKGPS 1338
Score = 31.2 bits (69), Expect = 9.1
Identities = 49/177 (27%), Positives = 54/177 (30%), Gaps = 25/177 (14%)
Query: 232 PAAPPTAVSPQPGAFLGLDRF--LLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPRE 289
P P P P G F + GP G PGSP AL P
Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPG----PPGSPGP--ALEGPKGNPG-------- 1255
Query: 290 PQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEG 349
PQ PP GLP E P K + P PG + P G+ G
Sbjct: 1256 PQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPG 1315
Query: 350 EEDAFEDAPRGSPGEEWAPEV--GEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPS 404
D G PG P + P G E E GP P PG P PS
Sbjct: 1316 LNGMKGDP--GLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP-----PGLPGPS 1365
>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
Length = 744
Score = 164 bits (415), Expect = 7e-40
Identities = 169/486 (34%), Positives = 201/486 (41%), Gaps = 89/486 (18%)
Query: 877 PPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPP------------PP 924
PP PP LPG +P + PQ P G +P P G+P P
Sbjct: 131 PPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPM 190
Query: 925 PLPGAGILPLPP-LPGAGIPPPPPLPGAAIPP----PPPLPGA-GIPLPPPLPGAGIPPP 978
+PG P P LPG G P P LPG P P LPG G+ P G G+P
Sbjct: 191 GIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGA 250
Query: 979 PPLPGA----GIPPPPPLPGAGIP-------PPPPLPGAGIPPPP----PLPGAGIPPPP 1023
P + G G P P LPG G P P PL G P P P+ G+ PP
Sbjct: 251 PGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPP 310
Query: 1024 PLPGAG------IPPPPPLPGA-------GIPPPPPLPGAGIP--PPPP-------LPGA 1061
+PG G IP P PG G+P PP LPG G P P P +PGA
Sbjct: 311 GIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGA 370
Query: 1062 ----GIPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGA-GIPPPPPLPGVGIPPPPPLPG 1115
G P PG G PP P LPG IP P PGA G P P G+ P PP P
Sbjct: 371 LGPRGEKGPIGAPGIGGPPGEPGLPG--IPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPK 428
Query: 1116 A-----GIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGA-GIPPPPPL 1168
G P P G G P LPG I P + G+P P +PG G P +
Sbjct: 429 GEPGLQGFPGKPGFLGEVGPPGMRGLPGP-IGPKGEAGQKGVPGLPGVPGLLGPKGEPGI 487
Query: 1169 PG-AGIPPPPPLPGVGIPP----PPPLPGV----GIPPPPPLPGAGIPPPPPLPGMGIPP 1219
PG G+ PP +PG+G P PP +PG G+P PP PG G P + G+ PP
Sbjct: 488 PGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIG---KPGVAGLHGPP 544
Query: 1220 APAPPLPPPGT-GIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQ 1278
L P G G+P PP GPP P + PTP G P + G+ G+
Sbjct: 545 GKPGALGPQGQPGLPGPP-----GPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPH 599
Query: 1279 DKGSRK 1284
G++K
Sbjct: 600 AYGAKK 605
Score = 149 bits (375), Expect = 3e-35
Identities = 170/506 (33%), Positives = 195/506 (38%), Gaps = 125/506 (24%)
Query: 872 GLGMVPPPPPPLPGMTVPTLPSTAIP-QPPPLQGTEMLPPPPPPLPGA---GIPPPPPLP 927
GL M P G P LP QP P G E +P +P A G P P
Sbjct: 67 GLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEP 126
Query: 928 GAGILPLPP-LPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGA-- 984
G P PP LPG GIP PG P PG G P P +PG P +PGA
Sbjct: 127 GPRGPPGPPGLPGHGIPGIKGKPG-----PQGYPGVGKPGMPGMPGK--PGAMGMPGAKG 179
Query: 985 -----GIPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGAGIPP----PPPLPGA-GIPPP 1033
G P +PG PP P LPG G P P LPG P P LPG G+ P
Sbjct: 180 EIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGP 239
Query: 1034 PPLPGAGIPPPPPLPGA----GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1089
G G+P P + G G P P LPG G P PG P PL G P P
Sbjct: 240 KGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPG----PQGPLGKPGAPGEP 295
Query: 1090 ----PLPGAGIPPPPPLPGV------GIPPPPPLPGA-------GIPPPPPLPGAGIPPP 1132
P+ G+ PP +PG+ GIP P PG G+P PP LPG G P
Sbjct: 296 GPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGF 355
Query: 1133 P----------------------PLPGAGIPPPPPLPRV-GIPPPPPLPGA-GIP----- 1163
P P+ GI PP P + GIP P PGA G P
Sbjct: 356 PGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGE 415
Query: 1164 --------PPPPLPGAGIPPPPPLPGV----------GIPPP------------PPLPGV 1193
PP P G+ P PG G+P P P LPGV
Sbjct: 416 GGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGV 475
Query: 1194 ----GIPPPPPLPG-AGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLP-VSGPPLLP 1247
G P +PG G+ PP +PG+G P+ P+ PP GIP P P + GPP P
Sbjct: 476 PGLLGPKGEPGIPGDQGLQGPPGIPGIG---GPSGPIGPP--GIPGPKGEPGLPGPPGFP 530
Query: 1248 QVGSSTLPTPQVCGFLPPPLPSGLFG 1273
+G P V G PP G G
Sbjct: 531 GIGK-----PGVAGLHGPPGKPGALG 551
Score = 138 bits (348), Expect = 4e-32
Identities = 169/514 (32%), Positives = 197/514 (38%), Gaps = 117/514 (22%)
Query: 856 PSPPPLPCTESSSSMPG-------------LGMVPPPPPP----LPGMTVPTLPST-AIP 897
P P +P + MPG +G+ P PP LPG+ P P P
Sbjct: 160 PGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQP 219
Query: 898 QPPPLQGTEMLPPP-----PPPLPGAGIPPPPPLPGAGILPLPP----LPGAGIPPPPPL 948
P +G + LP P P G G+P P + G + PP LPG G P
Sbjct: 220 GPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGF 279
Query: 949 PGAAIPPPPPLPGAGIPLPP----PLPGAGIPPPPPLPGAG------IPPPPPLPGA--- 995
PG P PL G P P P+ G+ PP +PG G IP P PG
Sbjct: 280 PG----PQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGE 335
Query: 996 ----GIPPPPPLPGAGIP--PPPP-------LPGA----GIPPPPPLPGAGIPPPPP-LP 1037
G+P PP LPG G P P P +PGA G P PG G PP P LP
Sbjct: 336 QGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLP 395
Query: 1038 GAGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGA-----GIPPPPPLPG-AGIPPPPP 1090
G IP P PGA G P P G P PP P G P P G G P
Sbjct: 396 G--IPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRG 453
Query: 1091 LPGA----------GIPPPPPLPGV-GIPPPPPLPG-AGIPPPPPLPGAGIPP----PPP 1134
LPG G+P P +PG+ G P +PG G+ PP +PG G P PP
Sbjct: 454 LPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPG 513
Query: 1135 LPGA----GIPPPPPLPRVGIPP------PPPLPGA----------GIPPPP--PLPGAG 1172
+PG G+P PP P +G P PP PGA G P PP P P A
Sbjct: 514 IPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAV 573
Query: 1173 IPPPPPLPGVGIPPPPPLPGVGIP--PPPPLPGA--GIPPPPPLPGMGIPPAPAPPLPPP 1228
+PP PP G +P G+GI PP GA G P P PP
Sbjct: 574 MPPTPPPQGEYLPD----MGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPV 629
Query: 1229 GTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGF 1262
G + LL PQ G T P V F
Sbjct: 630 GAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYF 663
Score = 130 bits (328), Expect = 8e-30
Identities = 143/413 (34%), Positives = 164/413 (39%), Gaps = 81/413 (19%)
Query: 855 IPSPPPL--PCTESSSSMPGLGMV--------PPPPPPLPGMTVPTLPSTAIPQPP-PLQ 903
+P P L P + MPG V PP P LPG+ P + PQ P
Sbjct: 230 LPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKP 289
Query: 904 GTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGA-GIPPPPPLPGA-------AIPP 955
G P P P+ G+ PP +PG G PG GIP P PG +P
Sbjct: 290 GAPGEPGPQGPIGVPGVQGPPGIPGIG------KPGQDGIPGQPGFPGGKGEQGLPGLPG 343
Query: 956 PPPLPGAGIP-LPPP--------LPGA----GIPPPPPLPGAGIPPPPP-LPGAGIPPPP 1001
PP LPG G P P P +PGA G P PG G PP P LPG IP P
Sbjct: 344 PPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPG--IPGPM 401
Query: 1002 PLPGA-GIPPPPPLPGAGIPPPPPLPGA-----GIPPPPPLPG-AGIPPPPPLPGA---- 1050
PGA G P P G P PP P G P P G G P LPG
Sbjct: 402 GPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPK 461
Query: 1051 ------GIPPPPPLPGA-GIPPPPPLPG-AGIPPPPPLPGAGIPP----PPPLPGA---- 1094
G+P P +PG G P +PG G+ PP +PG G P PP +PG
Sbjct: 462 GEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEP 521
Query: 1095 GIPPPPPLPGVGIPP------PPPLPGA-GIPPPPPLPGAGIPPPPPLPG-AGIPPPPPL 1146
G+P PP PG+G P PP PGA G P LPG P PP PG + PP P
Sbjct: 522 GLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGP--PGPPGPPGPPAVMPPTPP 579
Query: 1147 PRVGIPPPPPLPGAGIPPPPPL---PGAGIPPPPPLPGVGIPPPPPLPGVGIP 1196
P+ P L G+ PP G P +P P P VG P
Sbjct: 580 PQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
Score = 103 bits (256), Expect = 2e-21
Identities = 121/380 (31%), Positives = 145/380 (38%), Gaps = 64/380 (16%)
Query: 810 PPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSS 869
P P L G+PG Q P + + ++ IP P P +
Sbjct: 280 PGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDG--IPGQPGFPGGKGEQG 337
Query: 870 MPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPP--------LPGAGIP 921
+PGL P PP LPG+ P P P +G +P P PG G P
Sbjct: 338 LPGL----PGPPGLPGIGKPGFPG-----PKGDRGMGGVPGALGPRGEKGPIGAPGIGGP 388
Query: 922 PPPP-LPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGA-----GIPLPPPLPG-AG 974
P P LPG P+ P G P P G P PP P G P P G G
Sbjct: 389 PGEPGLPGIPG-PMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVG 447
Query: 975 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPLPG-AGIPPPPPLPGAGIPP 1032
P LPG I P G+P P +PG G P +PG G+ PP +PG G P
Sbjct: 448 PPGMRGLPGP-IGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPS 506
Query: 1033 ----PPPLPGA----GIPPPPPLPG------AGIPPPPPLPGA-GIPPPPPLPGAGIPPP 1077
PP +PG G+P PP PG AG+ PP PGA G P LPG P P
Sbjct: 507 GPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGP--PGP 564
Query: 1078 --PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL---PGAGIPPP 1132
PP P A +PP PP G +P G+GI G+ PP G P
Sbjct: 565 PGPPGPPAVMPPTPPPQGEYLPD----MGLGID--------GVKPPHAYGAKKGKNGGPA 612
Query: 1133 PPLPGAGIPPPPPLPRVGIP 1152
+P P P VG P
Sbjct: 613 YEMPAFTAELTAPFPPVGAP 632
Score = 37.4 bits (85), Expect = 0.13
Identities = 60/229 (26%), Positives = 83/229 (36%), Gaps = 28/229 (12%)
Query: 196 LSDIQQAIRLQQQQ--QQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFL 253
+ +IQ A R+ ++ ++ ++ L + +Q +G P PP PG + +
Sbjct: 90 MKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPG-LPGHGIPGIKGK 148
Query: 254 LGPSG--GAGEA-----PGSPDTEQALSALSDLPESLAAEPRE---PQQPPSPGGLPVSE 303
GP G G G+ PG P A ++ + P PQ PP P GLP
Sbjct: 149 PGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIG 208
Query: 304 APSLPA--AQPAAKDSPSSTAFPFPEA--GP-GEEAAGAPVRGAGDTDEEGEEDAF-EDA 357
P P QP K P P+ GP G++ G P G +G
Sbjct: 209 KPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMP----GAPGVKGPPGMHGPPG 264
Query: 358 PRGSPGEEWAPEVGEDAPQ----RLGEEPEEEAQGP-DAPAAASLPGSP 401
P G PG G PQ + G E QGP P PG P
Sbjct: 265 PVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIP 313
Score = 35.8 bits (81), Expect = 0.37
Identities = 59/252 (23%), Positives = 77/252 (30%), Gaps = 21/252 (8%)
Query: 255 GPSG--GAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQP 312
GP G G G PG P + P P P GG+ + P P +P
Sbjct: 378 GPIGAPGIGGPPGEPGLPGIPGPMG--PPGAIGFPG----PKGEGGIVGPQGPPGPKGEP 431
Query: 313 AAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAP--RGSPGEEWAPEV 370
+ P F PG P+ G+ ++G P G GE P
Sbjct: 432 GLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKG-VPGLPGVPGLLGPKGEPGIP-- 488
Query: 371 GEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPN 430
G+ Q G GP P PG P P P P P K L P
Sbjct: 489 GDQGLQ--GPPGIPGIGGPSGPIGP--PGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPP 544
Query: 431 HSP-SQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLAAGLSRSADWTEEL 489
P + P P + P P G + P ++ D GL
Sbjct: 545 GKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGID---GVKPPHAY 601
Query: 490 GARTPRVGGSAH 501
GA+ + GG A+
Sbjct: 602 GAKKGKNGGPAY 613
>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
Length = 744
Score = 164 bits (415), Expect = 7e-40
Identities = 169/486 (34%), Positives = 201/486 (41%), Gaps = 89/486 (18%)
Query: 877 PPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPP------------PP 924
PP PP LPG +P + PQ P G +P P G+P P
Sbjct: 131 PPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPM 190
Query: 925 PLPGAGILPLPP-LPGAGIPPPPPLPGAAIPP----PPPLPGA-GIPLPPPLPGAGIPPP 978
+PG P P LPG G P P LPG P P LPG G+ P G G+P
Sbjct: 191 GIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGA 250
Query: 979 PPLPGA----GIPPPPPLPGAGIP-------PPPPLPGAGIPPPP----PLPGAGIPPPP 1023
P + G G P P LPG G P P PL G P P P+ G+ PP
Sbjct: 251 PGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPP 310
Query: 1024 PLPGAG------IPPPPPLPGA-------GIPPPPPLPGAGIP--PPPP-------LPGA 1061
+PG G IP P PG G+P PP LPG G P P P +PGA
Sbjct: 311 GIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGA 370
Query: 1062 ----GIPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGA-GIPPPPPLPGVGIPPPPPLPG 1115
G P PG G PP P LPG IP P PGA G P P G+ P PP P
Sbjct: 371 LGPRGEKGPIGAPGIGGPPGEPGLPG--IPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPK 428
Query: 1116 A-----GIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGA-GIPPPPPL 1168
G P P G G P LPG I P + G+P P +PG G P +
Sbjct: 429 GEPGLQGFPGKPGFLGEVGPPGMRGLPGP-IGPKGEAGQKGVPGLPGVPGLLGPKGEPGI 487
Query: 1169 PG-AGIPPPPPLPGVGIPP----PPPLPGV----GIPPPPPLPGAGIPPPPPLPGMGIPP 1219
PG G+ PP +PG+G P PP +PG G+P PP PG G P + G+ PP
Sbjct: 488 PGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIG---KPGVAGLHGPP 544
Query: 1220 APAPPLPPPGT-GIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQ 1278
L P G G+P PP GPP P + PTP G P + G+ G+
Sbjct: 545 GKPGALGPQGQPGLPGPP-----GPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPH 599
Query: 1279 DKGSRK 1284
G++K
Sbjct: 600 AYGAKK 605
Score = 149 bits (375), Expect = 3e-35
Identities = 170/506 (33%), Positives = 195/506 (38%), Gaps = 125/506 (24%)
Query: 872 GLGMVPPPPPPLPGMTVPTLPSTAIP-QPPPLQGTEMLPPPPPPLPGA---GIPPPPPLP 927
GL M P G P LP QP P G E +P +P A G P P
Sbjct: 67 GLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEP 126
Query: 928 GAGILPLPP-LPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGA-- 984
G P PP LPG GIP PG P PG G P P +PG P +PGA
Sbjct: 127 GPRGPPGPPGLPGHGIPGIKGKPG-----PQGYPGVGKPGMPGMPGK--PGAMGMPGAKG 179
Query: 985 -----GIPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGAGIPP----PPPLPGA-GIPPP 1033
G P +PG PP P LPG G P P LPG P P LPG G+ P
Sbjct: 180 EIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGP 239
Query: 1034 PPLPGAGIPPPPPLPGA----GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1089
G G+P P + G G P P LPG G P PG P PL G P P
Sbjct: 240 KGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPG----PQGPLGKPGAPGEP 295
Query: 1090 ----PLPGAGIPPPPPLPGV------GIPPPPPLPGA-------GIPPPPPLPGAGIPPP 1132
P+ G+ PP +PG+ GIP P PG G+P PP LPG G P
Sbjct: 296 GPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGF 355
Query: 1133 P----------------------PLPGAGIPPPPPLPRV-GIPPPPPLPGA-GIP----- 1163
P P+ GI PP P + GIP P PGA G P
Sbjct: 356 PGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGE 415
Query: 1164 --------PPPPLPGAGIPPPPPLPGV----------GIPPP------------PPLPGV 1193
PP P G+ P PG G+P P P LPGV
Sbjct: 416 GGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGV 475
Query: 1194 ----GIPPPPPLPG-AGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLP-VSGPPLLP 1247
G P +PG G+ PP +PG+G P+ P+ PP GIP P P + GPP P
Sbjct: 476 PGLLGPKGEPGIPGDQGLQGPPGIPGIG---GPSGPIGPP--GIPGPKGEPGLPGPPGFP 530
Query: 1248 QVGSSTLPTPQVCGFLPPPLPSGLFG 1273
+G P V G PP G G
Sbjct: 531 GIGK-----PGVAGLHGPPGKPGALG 551
Score = 138 bits (348), Expect = 4e-32
Identities = 169/514 (32%), Positives = 197/514 (38%), Gaps = 117/514 (22%)
Query: 856 PSPPPLPCTESSSSMPG-------------LGMVPPPPPP----LPGMTVPTLPST-AIP 897
P P +P + MPG +G+ P PP LPG+ P P P
Sbjct: 160 PGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQP 219
Query: 898 QPPPLQGTEMLPPP-----PPPLPGAGIPPPPPLPGAGILPLPP----LPGAGIPPPPPL 948
P +G + LP P P G G+P P + G + PP LPG G P
Sbjct: 220 GPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGF 279
Query: 949 PGAAIPPPPPLPGAGIPLPP----PLPGAGIPPPPPLPGAG------IPPPPPLPGA--- 995
PG P PL G P P P+ G+ PP +PG G IP P PG
Sbjct: 280 PG----PQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGE 335
Query: 996 ----GIPPPPPLPGAGIP--PPPP-------LPGA----GIPPPPPLPGAGIPPPPP-LP 1037
G+P PP LPG G P P P +PGA G P PG G PP P LP
Sbjct: 336 QGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLP 395
Query: 1038 GAGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGA-----GIPPPPPLPG-AGIPPPPP 1090
G IP P PGA G P P G P PP P G P P G G P
Sbjct: 396 G--IPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRG 453
Query: 1091 LPGA----------GIPPPPPLPGV-GIPPPPPLPG-AGIPPPPPLPGAGIPP----PPP 1134
LPG G+P P +PG+ G P +PG G+ PP +PG G P PP
Sbjct: 454 LPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPG 513
Query: 1135 LPGA----GIPPPPPLPRVGIPP------PPPLPGA----------GIPPPP--PLPGAG 1172
+PG G+P PP P +G P PP PGA G P PP P P A
Sbjct: 514 IPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAV 573
Query: 1173 IPPPPPLPGVGIPPPPPLPGVGIP--PPPPLPGA--GIPPPPPLPGMGIPPAPAPPLPPP 1228
+PP PP G +P G+GI PP GA G P P PP
Sbjct: 574 MPPTPPPQGEYLPD----MGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPV 629
Query: 1229 GTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGF 1262
G + LL PQ G T P V F
Sbjct: 630 GAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYF 663
Score = 130 bits (328), Expect = 8e-30
Identities = 143/413 (34%), Positives = 164/413 (39%), Gaps = 81/413 (19%)
Query: 855 IPSPPPL--PCTESSSSMPGLGMV--------PPPPPPLPGMTVPTLPSTAIPQPP-PLQ 903
+P P L P + MPG V PP P LPG+ P + PQ P
Sbjct: 230 LPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKP 289
Query: 904 GTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGA-GIPPPPPLPGA-------AIPP 955
G P P P+ G+ PP +PG G PG GIP P PG +P
Sbjct: 290 GAPGEPGPQGPIGVPGVQGPPGIPGIG------KPGQDGIPGQPGFPGGKGEQGLPGLPG 343
Query: 956 PPPLPGAGIP-LPPP--------LPGA----GIPPPPPLPGAGIPPPPP-LPGAGIPPPP 1001
PP LPG G P P P +PGA G P PG G PP P LPG IP P
Sbjct: 344 PPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPG--IPGPM 401
Query: 1002 PLPGA-GIPPPPPLPGAGIPPPPPLPGA-----GIPPPPPLPG-AGIPPPPPLPGA---- 1050
PGA G P P G P PP P G P P G G P LPG
Sbjct: 402 GPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPK 461
Query: 1051 ------GIPPPPPLPGA-GIPPPPPLPG-AGIPPPPPLPGAGIPP----PPPLPGA---- 1094
G+P P +PG G P +PG G+ PP +PG G P PP +PG
Sbjct: 462 GEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEP 521
Query: 1095 GIPPPPPLPGVGIPP------PPPLPGA-GIPPPPPLPGAGIPPPPPLPG-AGIPPPPPL 1146
G+P PP PG+G P PP PGA G P LPG P PP PG + PP P
Sbjct: 522 GLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGP--PGPPGPPGPPAVMPPTPP 579
Query: 1147 PRVGIPPPPPLPGAGIPPPPPL---PGAGIPPPPPLPGVGIPPPPPLPGVGIP 1196
P+ P L G+ PP G P +P P P VG P
Sbjct: 580 PQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
Score = 103 bits (256), Expect = 2e-21
Identities = 121/380 (31%), Positives = 145/380 (38%), Gaps = 64/380 (16%)
Query: 810 PPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSS 869
P P L G+PG Q P + + ++ IP P P +
Sbjct: 280 PGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDG--IPGQPGFPGGKGEQG 337
Query: 870 MPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPP--------LPGAGIP 921
+PGL P PP LPG+ P P P +G +P P PG G P
Sbjct: 338 LPGL----PGPPGLPGIGKPGFPG-----PKGDRGMGGVPGALGPRGEKGPIGAPGIGGP 388
Query: 922 PPPP-LPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGA-----GIPLPPPLPG-AG 974
P P LPG P+ P G P P G P PP P G P P G G
Sbjct: 389 PGEPGLPGIPG-PMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVG 447
Query: 975 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPLPG-AGIPPPPPLPGAGIPP 1032
P LPG I P G+P P +PG G P +PG G+ PP +PG G P
Sbjct: 448 PPGMRGLPGP-IGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPS 506
Query: 1033 ----PPPLPGA----GIPPPPPLPG------AGIPPPPPLPGA-GIPPPPPLPGAGIPPP 1077
PP +PG G+P PP PG AG+ PP PGA G P LPG P P
Sbjct: 507 GPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGP--PGP 564
Query: 1078 --PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL---PGAGIPPP 1132
PP P A +PP PP G +P G+GI G+ PP G P
Sbjct: 565 PGPPGPPAVMPPTPPPQGEYLPD----MGLGID--------GVKPPHAYGAKKGKNGGPA 612
Query: 1133 PPLPGAGIPPPPPLPRVGIP 1152
+P P P VG P
Sbjct: 613 YEMPAFTAELTAPFPPVGAP 632
Score = 37.4 bits (85), Expect = 0.13
Identities = 60/229 (26%), Positives = 83/229 (36%), Gaps = 28/229 (12%)
Query: 196 LSDIQQAIRLQQQQ--QQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFL 253
+ +IQ A R+ ++ ++ ++ L + +Q +G P PP PG + +
Sbjct: 90 MKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPG-LPGHGIPGIKGK 148
Query: 254 LGPSG--GAGEA-----PGSPDTEQALSALSDLPESLAAEPRE---PQQPPSPGGLPVSE 303
GP G G G+ PG P A ++ + P PQ PP P GLP
Sbjct: 149 PGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIG 208
Query: 304 APSLPA--AQPAAKDSPSSTAFPFPEA--GP-GEEAAGAPVRGAGDTDEEGEEDAF-EDA 357
P P QP K P P+ GP G++ G P G +G
Sbjct: 209 KPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMP----GAPGVKGPPGMHGPPG 264
Query: 358 PRGSPGEEWAPEVGEDAPQ----RLGEEPEEEAQGP-DAPAAASLPGSP 401
P G PG G PQ + G E QGP P PG P
Sbjct: 265 PVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIP 313
Score = 35.8 bits (81), Expect = 0.37
Identities = 59/252 (23%), Positives = 77/252 (30%), Gaps = 21/252 (8%)
Query: 255 GPSG--GAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQP 312
GP G G G PG P + P P P GG+ + P P +P
Sbjct: 378 GPIGAPGIGGPPGEPGLPGIPGPMG--PPGAIGFPG----PKGEGGIVGPQGPPGPKGEP 431
Query: 313 AAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAP--RGSPGEEWAPEV 370
+ P F PG P+ G+ ++G P G GE P
Sbjct: 432 GLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKG-VPGLPGVPGLLGPKGEPGIP-- 488
Query: 371 GEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPN 430
G+ Q G GP P PG P P P P P K L P
Sbjct: 489 GDQGLQ--GPPGIPGIGGPSGPIGP--PGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPP 544
Query: 431 HSP-SQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLAAGLSRSADWTEEL 489
P + P P + P P G + P ++ D GL
Sbjct: 545 GKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGID---GVKPPHAY 601
Query: 490 GARTPRVGGSAH 501
GA+ + GG A+
Sbjct: 602 GAKKGKNGGPAY 613
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 162 bits (409), Expect = 3e-39
Identities = 192/651 (29%), Positives = 261/651 (40%), Gaps = 122/651 (18%)
Query: 692 ELERQYPALDTEVASGHQGLENGVTASGDVCLEALRLEEK----EVRHHRILEAKSIQTS 747
+LE++ P EVA + +E+G DV + A + ++ + R RI A
Sbjct: 501 DLEKETP---DEVAQ--EMIESGFFHESDVKIVAKSIRDRVALIQWRRERIWPA----LQ 551
Query: 748 PTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSH--QPTQ 805
P E+ V G P + PP Q + ++ P + D H PT
Sbjct: 552 PKEQQDV-------GSPDKARGPP-VPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTL 603
Query: 806 SISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTE 865
S + +GQG ++ ++ Q+S + + + ++ PSP C+
Sbjct: 604 PTSATSLASDSTFDSGQGS-------TVYSDSQSSQQSVMLGSLADAA--PSPAQCVCSP 654
Query: 866 SSS-------SMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGA 918
S S+P LG P PG+ V ++P+ A P P LQ P P + A
Sbjct: 655 PVSEGPVLPQSLPSLGAYQQPTAA-PGLPVGSVPAPACP--PSLQQHF----PDPAMSFA 707
Query: 919 GIPPPPPLPGAGILPLPPLPGAGIPP---PPPLPGAAIPPPPPLPGAGIPLPPPLPGAGI 975
+ PPP P +P PG PP PPPL P PLP P P +P +
Sbjct: 708 PVLPPPSTP------MPTGPGQPAPPGQQPPPL-----AQPTPLPQVLAP-QPVVPLQPV 755
Query: 976 PP--PPPL-PGAGIPPPPPLPGAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGA-GI 1030
PP PP L P + + P L +P P P A +PP PP+P +PP PL G G+
Sbjct: 756 PPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIP--VVPPITPLAGIDGL 813
Query: 1031 PPP-PPLPGAGIPPPPP---------LPGAGIPPPP-----PLPGAGIPPPP----PLPG 1071
PP P LP A +PP PP LP P PP PL +P PP +P
Sbjct: 814 PPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPC 873
Query: 1072 AGIPP--PPPLPGAGIPPP-----------PPLPGAGIPPP--PPLPGVGIPPPPPLPGA 1116
I P P +P + PP LPG + P P + +PP P
Sbjct: 874 RTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQ 933
Query: 1117 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PRVGIPPPPPLPGAGIPPPPPL--PGAG 1172
+ PP P +PP P LP + PP P P+ +PP P P + PP P+ P
Sbjct: 934 NMRATPPQP--ALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPV 991
Query: 1173 IPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGI 1232
+PP P LP P P LP P P + P P P P+PP
Sbjct: 992 LPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLS 1051
Query: 1233 PP-PPLLPVSGPPLLPQVGSS---------TLPTPQVCGFLP---PPLPSG 1270
PP P +L + P LLPQ SS ++PT Q LP PPLP G
Sbjct: 1052 PPLPEVLLPAAPELLPQFPSSLATVSASVQSVPT-QTATLLPPANPPLPGG 1101
Score = 61.2 bits (147), Expect = 8e-09
Identities = 75/281 (26%), Positives = 95/281 (33%), Gaps = 40/281 (14%)
Query: 825 PGSQPPHSISTEFQTSHEHSVSSA----FKNS-----------CNIPSPPPLPCTESSSS 869
PG+ PPH + T E S A ++ + C + P ESS
Sbjct: 1273 PGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPP 1332
Query: 870 MPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGA 929
+P + PP + P + + P ++ L P G PP P P +
Sbjct: 1333 LPLSSL----PPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSS 1388
Query: 930 GILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG----AGIPLPPPLPGAGIPPPPPLPGAG 985
P+ LP G P A P P G AG P P + + PL
Sbjct: 1389 P--PVTALPQDGAAP------ATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH 1440
Query: 986 IPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1044
P P G+ P P P A P +PPP P P P P G P
Sbjct: 1441 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL 1500
Query: 1045 PPLPGA-----GIPPPPPLPGAGIPPPPP--LPGAGIPPPP 1078
P GA P PPL G +PP PP L G PPP
Sbjct: 1501 PAAVGAVSLATSQLPSPPL-GPTVPPQPPSALESDGEGPPP 1540
Score = 58.9 bits (141), Expect = 4e-08
Identities = 68/248 (27%), Positives = 83/248 (33%), Gaps = 43/248 (17%)
Query: 768 PCPPGAESGPQTKFCS---EISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQ 824
P P ES P S E S +P + + QP+ SQ LL AG
Sbjct: 1322 PAPEAPESSPPLPLSSLPPEASQDSAPYKDQLS-SKEQPSFLASQ-----QLLSQAGPSN 1375
Query: 825 PGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLP 884
P PP ++ PS PP+ + P +P P
Sbjct: 1376 PPGAPPAPLA---------------------PSSPPVTALPQDGAAPATSTMPEPASGTA 1414
Query: 885 ----GMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGA 940
G P ++ + PL T P PL G+ P P P A P
Sbjct: 1415 SQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLV-VGLAPCTPAPEAASTRDASAPRE 1473
Query: 941 GIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGA-----GIPPPPPLPGAGIPPPPP--LP 993
+PPP P P P P G PL P GA P PPL G +PP PP L
Sbjct: 1474 PLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPL-GPTVPPQPPSALE 1532
Query: 994 GAGIPPPP 1001
G PPP
Sbjct: 1533 SDGEGPPP 1540
Score = 56.6 bits (135), Expect = 2e-07
Identities = 62/216 (28%), Positives = 72/216 (33%), Gaps = 26/216 (12%)
Query: 909 PPPPPPLPGAGIPPPPPLPGAG-------------ILPLPPLPGAGIPPPPPLPGAAIPP 955
P PPLP + +PP A + L AG PP P A + P
Sbjct: 1327 PESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAP 1386
Query: 956 PPPLPGAGIPLPPPLPGAGIPPPPP---LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1012
P P +P P P P AG P P + + PL P
Sbjct: 1387 SSP-PVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLA 1445
Query: 1013 PLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1071
P G+ P P P A P +PPP P P P P G P P G
Sbjct: 1446 VQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVG 1505
Query: 1072 A-----GIPPPPPLPGAGIPPPPP--LPGAGIPPPP 1100
A P PPL G +PP PP L G PPP
Sbjct: 1506 AVSLATSQLPSPPL-GPTVPPQPPSALESDGEGPPP 1540
Score = 55.8 bits (133), Expect = 3e-07
Identities = 79/287 (27%), Positives = 95/287 (33%), Gaps = 38/287 (13%)
Query: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP----PPPLPGAGIPP 1087
P P P + PPLP + +PP A P L P L AG
Sbjct: 1322 PAPEAPESS----PPLPLSSLPPEASQDSA--PYKDQLSSKEQPSFLASQQLLSQAGPSN 1375
Query: 1088 PPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP-----PPPLPG----AGIPPPPPLPGA 1138
PP G PP P P PP LP G P P P G AG P P +
Sbjct: 1376 PP-----GAPPAPLAPSS--PPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTS 1428
Query: 1139 GIPPPPPLPRVGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPP 1197
+ PL P P G+ P P P A P +PPP P P
Sbjct: 1429 ELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGT 1488
Query: 1198 PPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPV----SGPPLLPQVG--- 1250
P P G P P G P PP G +PP P + GPP P+VG
Sbjct: 1489 PQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPP--PRVGFVD 1546
Query: 1251 --SSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKP 1295
+L +P+ G + G R +EP R +P
Sbjct: 1547 STIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQP 1593
Score = 49.3 bits (116), Expect = 3e-05
Identities = 70/271 (25%), Positives = 97/271 (35%), Gaps = 65/271 (23%)
Query: 232 PAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEA--PGSP-------DTEQALSALSDLPES 282
P++PP PQ GA SG A +A PG+P +T Q L+ + P +
Sbjct: 1386 PSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLA 1445
Query: 283 L---------------------AAEPREPQQPPSPGGLPVSEAPSLPAAQPA-------A 314
+ A+ PREP PP+P P S P QPA
Sbjct: 1446 VQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVG 1505
Query: 315 KDSPSSTAFPFPEAGP----------GEEAAGAPVR-GAGDTDEEGEEDAF------EDA 357
S +++ P P GP + G P R G D+ + ++ E
Sbjct: 1506 AVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHV 1565
Query: 358 PRGSPGEEWAPEVGED----APQRLGEEPEEEAQGPDAPAAASLPGSP--APSQRCFKPY 411
P S EVG+ P R G++P E G D +LP P A S R P
Sbjct: 1566 PTSSASAGTPVEVGDRDFTLEPLR-GDQPRSEVCGGD----LALPPVPKEAVSGRVQLPQ 1620
Query: 412 PLITPCYIKTTTRQLSSPNHSPSQSPNQSPR 442
PL+ + T + S S + SPR
Sbjct: 1621 PLVEKSELAPTRGAVMEQGTSSSMTAESSPR 1651
Score = 48.5 bits (114), Expect = 6e-05
Identities = 60/214 (28%), Positives = 77/214 (35%), Gaps = 42/214 (19%)
Query: 758 PPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPP--PPS 815
PP LP +P PP PQ + L P R P Q + P P PP
Sbjct: 939 PPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTR---------PPQPVLPPQPMLPP- 988
Query: 816 LLWSAGQGQPGSQPPHSISTEFQTSH--EHSVSSAFKNSCNIPSPPPLPCTESSSSMPGL 873
Q QP + E H E + +A S + P + ++ +P
Sbjct: 989 ------QPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVP-- 1040
Query: 874 GMVPPPP-----PPLPGMTVPTLPS------------TAIPQPPPLQGTEMLPPPPPPLP 916
VP PP PPLP + +P P +A Q P Q +LPP PPLP
Sbjct: 1041 -TVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLP 1099
Query: 917 GA-GIPPPPPLPGAGILPLPPLPGAGIPPPPPLP 949
G GI P P + P+ A PP LP
Sbjct: 1100 GGPGIASPCPTVQLTVEPVQE-EQASQDKPPGLP 1132
Score = 40.4 bits (93), Expect = 0.015
Identities = 60/242 (24%), Positives = 86/242 (35%), Gaps = 17/242 (7%)
Query: 208 QQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSP 267
++ +Q Q QQ G P A P P A L +P
Sbjct: 1289 EESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAP 1348
Query: 268 DTEQALSALSDLPESLAAEPREPQQPPS--PGGLPVSEAPSLPAAQPAAKD--SPSSTAF 323
+Q S + P LA++ Q PS PG P APS P +D +P+++
Sbjct: 1349 YKDQLSS--KEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTM 1406
Query: 324 PFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFE--DAPRGSP----GEEWAPEVGEDAPQR 377
P P +G +A G ++ E + E +AP G E A R
Sbjct: 1407 PEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTR 1466
Query: 378 LGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCY--IKTTTRQLSSPNHSPSQ 435
P E P AP + G+P P+ +P PL+ + T QL SP P+
Sbjct: 1467 DASAPREPLP-PPAPEPSPHSGTPQPA--LGQPAPLLPAAVGAVSLATSQLPSPPLGPTV 1523
Query: 436 SP 437
P
Sbjct: 1524 PP 1525
Score = 36.6 bits (83), Expect = 0.22
Identities = 60/242 (24%), Positives = 79/242 (32%), Gaps = 34/242 (14%)
Query: 224 QQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESL 283
QQ +P P ++PQP L L P G+P + L + L
Sbjct: 729 QQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPL 788
Query: 284 AAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPE-------------AGP 330
A P PQ PP P P++ + PA D P++T P P A P
Sbjct: 789 AQVP--PQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAP 846
Query: 331 GEEAAGA-PVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGP 389
A+ A P++ G AP P P P L P A
Sbjct: 847 LPPASPALPLQAVKLPHPPG-------APLAMPCRTIVPNAPATIP-LLAVAPPGVAALS 898
Query: 390 DAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEP 449
A A LPG P YP P T SP+H+ P+ P+P
Sbjct: 899 IHSAVAQLPGQPV--------YPAAFPQMAPTDVP--PSPHHTVQNMRATPPQPALPPQP 948
Query: 450 SL 451
+L
Sbjct: 949 TL 950
Score = 36.2 bits (82), Expect = 0.28
Identities = 51/177 (28%), Positives = 65/177 (36%), Gaps = 22/177 (12%)
Query: 234 APPTAVSPQPGAFLGLDRFLLG------PSGGAGEAPGS--PDTEQALSALSDLPESLAA 285
A P A + +PG L R ++ P A EAPG P Q L L A
Sbjct: 27 AEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIA 86
Query: 286 EPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTA-FPFPEAGPGEEAAGAPVRGAGD 344
E G P + AP+ AQP A +P+ P PG + A V A
Sbjct: 87 ERAR--------GRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPA 138
Query: 345 TDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPD--APAAASLPG 399
D E+A A +E A E + + +EPEEE D A SL G
Sbjct: 139 PDGGPREEA---AATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDEDDLKAVATSLDG 192
Score = 33.5 bits (75), Expect = 1.8
Identities = 54/211 (25%), Positives = 67/211 (31%), Gaps = 34/211 (16%)
Query: 144 PGGPGPAEARVGGRPIAEDVETAAGAQDGQRTSSGSDTDIYSFHSATEQEDLLSDIQQAI 203
PG P P E + + T+A TS SD+ S +T D
Sbjct: 584 PGPPEPEEPEADQHLLPPTLPTSA-------TSLASDSTFDSGQGSTVYSD--------- 627
Query: 204 RLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSG---GA 260
Q QQ + L Q P V PQ LG + G G+
Sbjct: 628 --SQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGS 685
Query: 261 GEAPGSPDTEQ------ALSALSDLPESLAAEPREPQQPPSPGGLPVSEA-----PSLPA 309
AP P + Q A+S LP P P QP PG P A P + A
Sbjct: 686 VPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLA 745
Query: 310 AQPAAKDSPSSTAFPFPEAGPGEEAAGAPVR 340
QP P P P P + GAP +
Sbjct: 746 PQPVVPLQPVPPHLP-PYLAPASQ-VGAPAQ 774
Score = 32.7 bits (73), Expect = 3.1
Identities = 63/276 (22%), Positives = 94/276 (34%), Gaps = 40/276 (14%)
Query: 232 PAAPPT----AVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALS--DLPES--- 282
P AP T AV+P A L + + PG P A ++ D+P S
Sbjct: 878 PNAPATIPLLAVAPPGVAALSIH-------SAVAQLPGQPVYPAAFPQMAPTDVPPSPHH 930
Query: 283 ----LAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAP 338
+ A P +P PP P P P P P P T P P P P
Sbjct: 931 TVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQP 990
Query: 339 V---RGAGDTDEEGEEDAFED--APRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPA 393
V + A E + + AP +PG + +G AP + + AQ P P
Sbjct: 991 VLPPQPALPVRPEPLQPHLPEQAAPAATPGSQIL--LGHPAPYAV----DVAAQVPTVPV 1044
Query: 394 AASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSR 453
+ SP + P + P + L++ + S P Q+ + P L
Sbjct: 1045 PPAAVLSPPLPEVLLPAAPELLPQF----PSSLATVSASVQSVPTQTATLLPPANPPLPG 1100
Query: 454 GSRTA-----LASVAAPAKKHRADGGLAAGLSRSAD 484
G A + P ++ +A GL +S +
Sbjct: 1101 GPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCE 1136
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 156 bits (394), Expect = 2e-37
Identities = 130/370 (35%), Positives = 147/370 (39%), Gaps = 72/370 (19%)
Query: 880 PPPLPGMT---VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPP 936
PP L G+ +P L STA G P PP P P G G P+P
Sbjct: 97 PPGLGGLFQAGMPKLRSTANRDND--SGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPS 154
Query: 937 LPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIP--------PPPPLPGAGIPP 988
PG PP P PP P + +PPP+P P PP+PG P
Sbjct: 155 -PGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGG---P 210
Query: 989 PPPLPGAGIPPPPPLPG-------AGIPPPPPL----PGAGIPPPPPLPGAGIPPPPPLP 1037
P PG P PPP PG G PL P + PP PP P + PP
Sbjct: 211 RQPSPG---PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP-- 265
Query: 1038 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1097
PPPPP+ P + +PPPPP P P P A PPP P
Sbjct: 266 ----PPPPPVGNR-----PSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP------P 310
Query: 1098 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIP-----PPPPLPGAGIPPPPPLPRVGIP 1152
PPP PG PPP P +G P LP + PP P PG P PPP P P
Sbjct: 311 PPPSRPG---PPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP-PSERPP 366
Query: 1153 PP---PPLPGAGIPPPPPLPGAG-----IPPPPPLP---GVGIPPPPPLPGVGIPPPPPL 1201
PP PP +PPPPP+ G +P P LP GV P P P P PP
Sbjct: 367 PPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRP----PLPPDR 422
Query: 1202 PGAGIPPPPP 1211
P AG PPPPP
Sbjct: 423 PSAGAPPPPP 432
Score = 152 bits (383), Expect = 4e-36
Identities = 141/451 (31%), Positives = 172/451 (38%), Gaps = 94/451 (20%)
Query: 821 GQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPL--PCTESSSSMPGLGMVPP 878
G G G P + FQ S+A +++ + S PPL P S+S+ P
Sbjct: 88 GGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPF------ 141
Query: 879 PPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPL---- 934
PP PG +PS PP +PPP P + PPP+P P+
Sbjct: 142 SPPSGPGRF--PVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTP-RPIQSSP 198
Query: 935 -----PPLPGAGIPPPPPLPGAAIPPPPPLPG-----------AGIPLPPPLPGAGIPPP 978
PP+PG P P PG P PPP PG PL P + PP
Sbjct: 199 HNRGSPPVPGG---PRQPSPG---PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPL 252
Query: 979 PPLPGAGI---PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1035
PP P + PPPPP P + P + +PPPPP P P P A PPP
Sbjct: 253 PPTPSRALDDKPPPPPPP---VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP 309
Query: 1036 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI---PPPPPLPGAGIPPPPPLP 1092
PPPP PG PPP P +G P LP + PPLP G P P P
Sbjct: 310 ------PPPPSRPG---PPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP 360
Query: 1093 GAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAG-----IPPPPPLPG-AGIPPPPPL 1146
+ PPPP + PP G +PPPPP+ G +P P LP +G+ P
Sbjct: 361 PSERPPPP------VRDPPGRSGP-LPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSG 413
Query: 1147 PRVGIPPPPPLPGAGIPPPPP------------------------LPGAGIPPPPPLPGV 1182
PR P PP P AG PPPPP P + +PPP P
Sbjct: 414 PRP--PLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQT 471
Query: 1183 GIPPPPPLPGVGIPPPPPLPGAGIPPPPPLP 1213
P L G PP PP+P
Sbjct: 472 TKSYPSKLARNESRSGSNRRERGAPPLPPIP 502
Score = 148 bits (374), Expect = 4e-35
Identities = 126/348 (36%), Positives = 140/348 (40%), Gaps = 76/348 (21%)
Query: 923 PPPLPGAG----ILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPP 978
PP LP G P P G G P P PG PP P +PPP P G P
Sbjct: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPS-PGHRSGPPEPQRNR---MPPPRPDVGSKPD 181
Query: 979 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1038
IPPP P I P G+ PP+PG P P PG P PPP PG
Sbjct: 182 ------SIPPPVPSTPRPIQSSPHNRGS-----PPVPGG---PRQPSPG---PTPPPFPG 224
Query: 1039 -------AGIPPPPPL----PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1087
G PL P + PP PP P + PP PPPPP+
Sbjct: 225 NRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP------PPPPPVGNR---- 274
Query: 1088 PPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1147
P + +PPPPP P P P A PPP PPPP PG PPP P
Sbjct: 275 -PSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP------PPPPSRPG---PPPLPPS 324
Query: 1148 RVGIPPPPPLPGAGIP-----PPPPLPGAGIPPPPPLPGVGIPPP---PPLPGVGIPPPP 1199
G P LP + PP P PG P PPP P PPP PP +PPPP
Sbjct: 325 SSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP-PSERPPPPVRDPPGRSGPLPPPP 383
Query: 1200 PLPGAG-----IPPPPPLP---GMGIPPA-PAPPLPP--PGTGIPPPP 1236
P+ G +P P LP G+ P + P PPLPP P G PPPP
Sbjct: 384 PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPP 431
Score = 144 bits (363), Expect = 7e-34
Identities = 131/411 (31%), Positives = 154/411 (37%), Gaps = 110/411 (26%)
Query: 820 AGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPP 879
+G +P PP ST + S F P P P S P +PPP
Sbjct: 121 SGGSRPPLLPPGGRSTSAKPFSPPSGPGRF--------PVPSPGHRSGPPEPQRNRMPPP 172
Query: 880 PPPL---PGMTVPTLPSTAIP--QPPPLQGTEMLPPPP-PPLPGAGIPPPPPLPG----- 928
P + P P +PST P P +G+ +P P P PG P PPP PG
Sbjct: 173 RPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPG---PTPPPFPGNRGTA 229
Query: 929 --AGILPLPPL----PGAGIPPPPPLPGAAI---PPPPPLPGAGIPLPPPLPGAGIPPPP 979
G + PL P + PP PP P A+ PPPPP P + P + +PPPP
Sbjct: 230 LGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPP---VGNRPSIHREAVPPPP 286
Query: 980 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1039
P P P P A PPP PPPP PG PPP P +G P LP
Sbjct: 287 PQNNKPPVPSTPRPSASSQAPPP------PPPPSRPG---PPPLPPSSSGNDETPRLPQR 337
Query: 1040 GIP-----PPPPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAG-----IP 1086
+ PP P PG P PPP P PPP PP +PPPPP+ G +P
Sbjct: 338 NLSLSSSTPPLPSPGRSGPLPPP-PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALP 396
Query: 1087 PPPPLP---GAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL------------------- 1124
P LP G P P P P PP P AG PPPPP
Sbjct: 397 ATPQLPSRSGVDSPRSGPRP----PLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWES 452
Query: 1125 -----PGAGIPPPPPLPGA----------------------GIPPPPPLPR 1148
P + +PPP P G PP PP+PR
Sbjct: 453 RFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPIPR 503
Score = 120 bits (300), Expect = 1e-26
Identities = 106/336 (31%), Positives = 130/336 (38%), Gaps = 71/336 (21%)
Query: 994 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPLPGA-- 1050
G PP P G P P +G P P+P G PP P +PPP P G+
Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSG-PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP 180
Query: 1051 -GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP 1109
IPPP P I P G+ PP+PG P P PG P PPP PG
Sbjct: 181 DSIPPPVPSTPRPIQSSPHNRGS-----PPVPGG---PRQPSPG---PTPPPFPG---NR 226
Query: 1110 PPPLPGAGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPP 1166
L G I P P + PP PP P + PP PPPPP+ P
Sbjct: 227 GTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP------PPPPPVGNR-----P 275
Query: 1167 PLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLP------------- 1213
+ +PPPPP P P P PPP P P PPPLP
Sbjct: 276 SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335
Query: 1214 ------GMGIPPAPAP----PLPPPGTGIPPPPLL-------PVSGPPLLPQVGSSTLPT 1256
PP P+P PLPPP + PPPP+ P+ PP + + GS++
Sbjct: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRAL 395
Query: 1257 PQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRP 1292
P P LPS G++ + + P+ P RP
Sbjct: 396 PAT-----PQLPS---RSGVDSPRSGPRPPLPPDRP 423
Score = 63.9 bits (154), Expect = 1e-09
Identities = 78/276 (28%), Positives = 97/276 (35%), Gaps = 43/276 (15%)
Query: 743 SIQTSPTEEGGVLT----LPP-----VDGLPGRPPCPPG------AESGPQTKFCSEISL 787
SI+ SP + LPP +D P PP P G E+ P +
Sbjct: 234 SIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPP 293
Query: 788 IVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSS 847
+ S R S + P S+P PPP S+G + P ++S T S
Sbjct: 294 VPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPG- 352
Query: 848 AFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLP--GMTVPTLPSTAIPQPPPLQGT 905
S +P PP PG PPPPP+ G T LP+T PQ P G
Sbjct: 353 ---RSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPAT--PQLPSRSGV 407
Query: 906 EM-----LPPPPPPLPGAGIPPPPPLPGAGI---LPLPPL-----------PGAGIPPPP 946
+ PP PP P AG PPPPP P I P P + +PPP
Sbjct: 408 DSPRSGPRPPLPPDRPSAGAPPPPP-PSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPE 466
Query: 947 PLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLP 982
P P L G PP PP+P
Sbjct: 467 PYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPIP 502
Score = 36.6 bits (83), Expect = 0.22
Identities = 98/429 (22%), Positives = 131/429 (30%), Gaps = 99/429 (23%)
Query: 38 GSGGKKALGKHGKGGGGGGGGGESGKKKSKSDSRASVFSNL-RIRKNLSKGKGAGGSRED 96
G GG G G GGGGGGGGG S + + ++R ++ +GGSR
Sbjct: 68 GGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPP 127
Query: 97 VLDSQALQTGELDSAHSLLTKTPDLSLSADEAGLSDTECADPFEVTGPGGPG----PAEA 152
+L T A PF + P GPG P+
Sbjct: 128 LLPPGGRSTS-----------------------------AKPF--SPPSGPGRFPVPSPG 156
Query: 153 RVGGRPIAEDVETAAGAQDGQRTSSGSDTDIYSFHSATEQEDLLSDIQQAIRLQQQQQQQ 212
G P E R GS D I + +
Sbjct: 157 HRSGPP-----EPQRNRMPPPRPDVGSKPD---------------SIPPPV---PSTPRP 193
Query: 213 LQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSP-DTEQ 271
+Q + G +P+ PT P PG G + G G SP +
Sbjct: 194 IQSSPHNRGSPPVPGGPRQPSPGPTP-PPFPGN--------RGTALGGGSIRQSPLSSSS 244
Query: 272 ALSALSDLP--ESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAG 329
S LP S A + + P PP G P ++P P + P + P P A
Sbjct: 245 PFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVP-PPPPQNNKPPVPSTPRPSAS 303
Query: 330 PGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGP 389
P G P S G + P + PQR P
Sbjct: 304 SQAPPPPPPPSRPGP----------PPLPPSSSGNDETPRL----PQRNLSLSSSTPPLP 349
Query: 390 DAPAAASLPGSPAPSQRCFKPY--------PLITPCYIK---TTTRQLSSPNHSPSQSPN 438
+ LP P PS+R P PL P + +T+R L + PS+S
Sbjct: 350 SPGRSGPLP--PPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGV 407
Query: 439 QSPRIKRRP 447
SPR RP
Sbjct: 408 DSPRSGPRP 416
Score = 31.6 bits (70), Expect = 7.0
Identities = 60/251 (23%), Positives = 80/251 (31%), Gaps = 49/251 (19%)
Query: 228 GAEEPAAPPTAVSPQPGAFL---GLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLA 284
G+ P PP S F G RF + PS G P P
Sbjct: 123 GSRPPLLPPGGRSTSAKPFSPPSGPGRFPV-PSPGHRSGPPEPQRN-------------- 167
Query: 285 AEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAG-------- 336
R P P G P S P +P+ + SP + P GP + + G
Sbjct: 168 ---RMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPG 224
Query: 337 --APVRGAGDTDEE--GEEDAFEDAPRGSPGEEWA-PEVGEDAPQRLGEEP--EEEAQGP 389
G G + F + P P A + P +G P EA P
Sbjct: 225 NRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPP 284
Query: 390 DAPA--AASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPN-QSPRIKRR 446
P +P +P PS P P P + P PS S N ++PR+
Sbjct: 285 PPPQNNKPPVPSTPRPSASSQAPPPPPPP-------SRPGPPPLPPSSSGNDETPRL--- 334
Query: 447 PEPSLSRGSRT 457
P+ +LS S T
Sbjct: 335 PQRNLSLSSST 345
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 156 bits (394), Expect = 2e-37
Identities = 130/370 (35%), Positives = 147/370 (39%), Gaps = 72/370 (19%)
Query: 880 PPPLPGMT---VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPP 936
PP L G+ +P L STA G P PP P P G G P+P
Sbjct: 97 PPGLGGLFQAGMPKLRSTANRDND--SGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPS 154
Query: 937 LPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIP--------PPPPLPGAGIPP 988
PG PP P PP P + +PPP+P P PP+PG P
Sbjct: 155 -PGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGG---P 210
Query: 989 PPPLPGAGIPPPPPLPG-------AGIPPPPPL----PGAGIPPPPPLPGAGIPPPPPLP 1037
P PG P PPP PG G PL P + PP PP P + PP
Sbjct: 211 RQPSPG---PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP-- 265
Query: 1038 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1097
PPPPP+ P + +PPPPP P P P A PPP P
Sbjct: 266 ----PPPPPVGNR-----PSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP------P 310
Query: 1098 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIP-----PPPPLPGAGIPPPPPLPRVGIP 1152
PPP PG PPP P +G P LP + PP P PG P PPP P P
Sbjct: 311 PPPSRPG---PPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP-PSERPP 366
Query: 1153 PP---PPLPGAGIPPPPPLPGAG-----IPPPPPLP---GVGIPPPPPLPGVGIPPPPPL 1201
PP PP +PPPPP+ G +P P LP GV P P P P PP
Sbjct: 367 PPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRP----PLPPDR 422
Query: 1202 PGAGIPPPPP 1211
P AG PPPPP
Sbjct: 423 PSAGAPPPPP 432
Score = 152 bits (383), Expect = 4e-36
Identities = 141/451 (31%), Positives = 172/451 (38%), Gaps = 94/451 (20%)
Query: 821 GQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPL--PCTESSSSMPGLGMVPP 878
G G G P + FQ S+A +++ + S PPL P S+S+ P
Sbjct: 88 GGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPF------ 141
Query: 879 PPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPL---- 934
PP PG +PS PP +PPP P + PPP+P P+
Sbjct: 142 SPPSGPGRF--PVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTP-RPIQSSP 198
Query: 935 -----PPLPGAGIPPPPPLPGAAIPPPPPLPG-----------AGIPLPPPLPGAGIPPP 978
PP+PG P P PG P PPP PG PL P + PP
Sbjct: 199 HNRGSPPVPGG---PRQPSPG---PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPL 252
Query: 979 PPLPGAGI---PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1035
PP P + PPPPP P + P + +PPPPP P P P A PPP
Sbjct: 253 PPTPSRALDDKPPPPPPP---VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP 309
Query: 1036 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI---PPPPPLPGAGIPPPPPLP 1092
PPPP PG PPP P +G P LP + PPLP G P P P
Sbjct: 310 ------PPPPSRPG---PPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP 360
Query: 1093 GAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAG-----IPPPPPLPG-AGIPPPPPL 1146
+ PPPP + PP G +PPPPP+ G +P P LP +G+ P
Sbjct: 361 PSERPPPP------VRDPPGRSGP-LPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSG 413
Query: 1147 PRVGIPPPPPLPGAGIPPPPP------------------------LPGAGIPPPPPLPGV 1182
PR P PP P AG PPPPP P + +PPP P
Sbjct: 414 PRP--PLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQT 471
Query: 1183 GIPPPPPLPGVGIPPPPPLPGAGIPPPPPLP 1213
P L G PP PP+P
Sbjct: 472 TKSYPSKLARNESRSGSNRRERGAPPLPPIP 502
Score = 148 bits (374), Expect = 4e-35
Identities = 126/348 (36%), Positives = 140/348 (40%), Gaps = 76/348 (21%)
Query: 923 PPPLPGAG----ILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPP 978
PP LP G P P G G P P PG PP P +PPP P G P
Sbjct: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPS-PGHRSGPPEPQRNR---MPPPRPDVGSKPD 181
Query: 979 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1038
IPPP P I P G+ PP+PG P P PG P PPP PG
Sbjct: 182 ------SIPPPVPSTPRPIQSSPHNRGS-----PPVPGG---PRQPSPG---PTPPPFPG 224
Query: 1039 -------AGIPPPPPL----PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1087
G PL P + PP PP P + PP PPPPP+
Sbjct: 225 NRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP------PPPPPVGNR---- 274
Query: 1088 PPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1147
P + +PPPPP P P P A PPP PPPP PG PPP P
Sbjct: 275 -PSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP------PPPPSRPG---PPPLPPS 324
Query: 1148 RVGIPPPPPLPGAGIP-----PPPPLPGAGIPPPPPLPGVGIPPP---PPLPGVGIPPPP 1199
G P LP + PP P PG P PPP P PPP PP +PPPP
Sbjct: 325 SSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP-PSERPPPPVRDPPGRSGPLPPPP 383
Query: 1200 PLPGAG-----IPPPPPLP---GMGIPPA-PAPPLPP--PGTGIPPPP 1236
P+ G +P P LP G+ P + P PPLPP P G PPPP
Sbjct: 384 PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPP 431
Score = 144 bits (363), Expect = 7e-34
Identities = 131/411 (31%), Positives = 154/411 (37%), Gaps = 110/411 (26%)
Query: 820 AGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPP 879
+G +P PP ST + S F P P P S P +PPP
Sbjct: 121 SGGSRPPLLPPGGRSTSAKPFSPPSGPGRF--------PVPSPGHRSGPPEPQRNRMPPP 172
Query: 880 PPPL---PGMTVPTLPSTAIP--QPPPLQGTEMLPPPP-PPLPGAGIPPPPPLPG----- 928
P + P P +PST P P +G+ +P P P PG P PPP PG
Sbjct: 173 RPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPG---PTPPPFPGNRGTA 229
Query: 929 --AGILPLPPL----PGAGIPPPPPLPGAAI---PPPPPLPGAGIPLPPPLPGAGIPPPP 979
G + PL P + PP PP P A+ PPPPP P + P + +PPPP
Sbjct: 230 LGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPP---VGNRPSIHREAVPPPP 286
Query: 980 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1039
P P P P A PPP PPPP PG PPP P +G P LP
Sbjct: 287 PQNNKPPVPSTPRPSASSQAPPP------PPPPSRPG---PPPLPPSSSGNDETPRLPQR 337
Query: 1040 GIP-----PPPPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAG-----IP 1086
+ PP P PG P PPP P PPP PP +PPPPP+ G +P
Sbjct: 338 NLSLSSSTPPLPSPGRSGPLPPP-PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALP 396
Query: 1087 PPPPLP---GAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL------------------- 1124
P LP G P P P P PP P AG PPPPP
Sbjct: 397 ATPQLPSRSGVDSPRSGPRP----PLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWES 452
Query: 1125 -----PGAGIPPPPPLPGA----------------------GIPPPPPLPR 1148
P + +PPP P G PP PP+PR
Sbjct: 453 RFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPIPR 503
Score = 120 bits (300), Expect = 1e-26
Identities = 106/336 (31%), Positives = 130/336 (38%), Gaps = 71/336 (21%)
Query: 994 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPLPGA-- 1050
G PP P G P P +G P P+P G PP P +PPP P G+
Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSG-PGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP 180
Query: 1051 -GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP 1109
IPPP P I P G+ PP+PG P P PG P PPP PG
Sbjct: 181 DSIPPPVPSTPRPIQSSPHNRGS-----PPVPGG---PRQPSPG---PTPPPFPG---NR 226
Query: 1110 PPPLPGAGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPP 1166
L G I P P + PP PP P + PP PPPPP+ P
Sbjct: 227 GTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP------PPPPPVGNR-----P 275
Query: 1167 PLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLP------------- 1213
+ +PPPPP P P P PPP P P PPPLP
Sbjct: 276 SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335
Query: 1214 ------GMGIPPAPAP----PLPPPGTGIPPPPLL-------PVSGPPLLPQVGSSTLPT 1256
PP P+P PLPPP + PPPP+ P+ PP + + GS++
Sbjct: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRAL 395
Query: 1257 PQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRP 1292
P P LPS G++ + + P+ P RP
Sbjct: 396 PAT-----PQLPS---RSGVDSPRSGPRPPLPPDRP 423
Score = 63.9 bits (154), Expect = 1e-09
Identities = 78/276 (28%), Positives = 97/276 (35%), Gaps = 43/276 (15%)
Query: 743 SIQTSPTEEGGVLT----LPP-----VDGLPGRPPCPPG------AESGPQTKFCSEISL 787
SI+ SP + LPP +D P PP P G E+ P +
Sbjct: 234 SIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPP 293
Query: 788 IVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSS 847
+ S R S + P S+P PPP S+G + P ++S T S
Sbjct: 294 VPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPG- 352
Query: 848 AFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLP--GMTVPTLPSTAIPQPPPLQGT 905
S +P PP PG PPPPP+ G T LP+T PQ P G
Sbjct: 353 ---RSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPAT--PQLPSRSGV 407
Query: 906 EM-----LPPPPPPLPGAGIPPPPPLPGAGI---LPLPPL-----------PGAGIPPPP 946
+ PP PP P AG PPPPP P I P P + +PPP
Sbjct: 408 DSPRSGPRPPLPPDRPSAGAPPPPP-PSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPE 466
Query: 947 PLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLP 982
P P L G PP PP+P
Sbjct: 467 PYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPIP 502
Score = 36.6 bits (83), Expect = 0.22
Identities = 98/429 (22%), Positives = 131/429 (30%), Gaps = 99/429 (23%)
Query: 38 GSGGKKALGKHGKGGGGGGGGGESGKKKSKSDSRASVFSNL-RIRKNLSKGKGAGGSRED 96
G GG G G GGGGGGGGG S + + ++R ++ +GGSR
Sbjct: 68 GGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPP 127
Query: 97 VLDSQALQTGELDSAHSLLTKTPDLSLSADEAGLSDTECADPFEVTGPGGPG----PAEA 152
+L T A PF + P GPG P+
Sbjct: 128 LLPPGGRSTS-----------------------------AKPF--SPPSGPGRFPVPSPG 156
Query: 153 RVGGRPIAEDVETAAGAQDGQRTSSGSDTDIYSFHSATEQEDLLSDIQQAIRLQQQQQQQ 212
G P E R GS D I + +
Sbjct: 157 HRSGPP-----EPQRNRMPPPRPDVGSKPD---------------SIPPPV---PSTPRP 193
Query: 213 LQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSP-DTEQ 271
+Q + G +P+ PT P PG G + G G SP +
Sbjct: 194 IQSSPHNRGSPPVPGGPRQPSPGPTP-PPFPGN--------RGTALGGGSIRQSPLSSSS 244
Query: 272 ALSALSDLP--ESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAG 329
S LP S A + + P PP G P ++P P + P + P P A
Sbjct: 245 PFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVP-PPPPQNNKPPVPSTPRPSAS 303
Query: 330 PGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGP 389
P G P S G + P + PQR P
Sbjct: 304 SQAPPPPPPPSRPGP----------PPLPPSSSGNDETPRL----PQRNLSLSSSTPPLP 349
Query: 390 DAPAAASLPGSPAPSQRCFKPY--------PLITPCYIK---TTTRQLSSPNHSPSQSPN 438
+ LP P PS+R P PL P + +T+R L + PS+S
Sbjct: 350 SPGRSGPLP--PPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGV 407
Query: 439 QSPRIKRRP 447
SPR RP
Sbjct: 408 DSPRSGPRP 416
Score = 31.6 bits (70), Expect = 7.0
Identities = 60/251 (23%), Positives = 80/251 (31%), Gaps = 49/251 (19%)
Query: 228 GAEEPAAPPTAVSPQPGAFL---GLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLA 284
G+ P PP S F G RF + PS G P P
Sbjct: 123 GSRPPLLPPGGRSTSAKPFSPPSGPGRFPV-PSPGHRSGPPEPQRN-------------- 167
Query: 285 AEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAG-------- 336
R P P G P S P +P+ + SP + P GP + + G
Sbjct: 168 ---RMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPG 224
Query: 337 --APVRGAGDTDEE--GEEDAFEDAPRGSPGEEWA-PEVGEDAPQRLGEEP--EEEAQGP 389
G G + F + P P A + P +G P EA P
Sbjct: 225 NRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPP 284
Query: 390 DAPA--AASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPN-QSPRIKRR 446
P +P +P PS P P P + P PS S N ++PR+
Sbjct: 285 PPPQNNKPPVPSTPRPSASSQAPPPPPPP-------SRPGPPPLPPSSSGNDETPRL--- 334
Query: 447 PEPSLSRGSRT 457
P+ +LS S T
Sbjct: 335 PQRNLSLSSST 345
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 155 bits (392), Expect = 3e-37
Identities = 152/589 (25%), Positives = 253/589 (42%), Gaps = 95/589 (16%)
Query: 1136 PGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGI 1195
P G PLP PPPPPLP + P G PP PP P PPPPP P
Sbjct: 516 PTMGAASSGPLP----PPPPPLPPSSDTPETVQNGPVTPPMPPPP----PPPPPPP---- 563
Query: 1196 PPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLP 1255
PPPPP PPPPPLPG PAPPL PP PP P G+S+
Sbjct: 564 PPPPP------PPPPPLPGPAAETVPAPPLAPPLPSAPPLP-------------GTSS-- 602
Query: 1256 TPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSSTSLIW 1315
P+ +F G+ K K+PI+ M W + K + ++
Sbjct: 603 ------------PTVVFNSGLAAVK--IKKPIKTKFRMPVFNWVAL----KPNQINGTVF 644
Query: 1316 EKIEEPSI----DCHEFEELFSKTAVKERKKPISDTISK--TKAKQVVKLLSNKRSQAVG 1369
+I++ I + EFEE+F KT + +S + K K V LL R++ +
Sbjct: 645 NEIDDERILEDLNVDEFEEIF-KTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLA 703
Query: 1370 ILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIEKHGRSSKDKENAK 1429
I + +I A+ D + ++ ++ L +E++ + + R K EN
Sbjct: 704 ITLRKAGKTADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLEN-- 761
Query: 1430 SLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQKLCETLKNGPGVMQ 1489
L ++F+ + S I +++ + F F+ESI + +L + ++K+ + +
Sbjct: 762 -LSDEDRFMMQFSKIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKK 820
Query: 1490 VLGLVLAFGNYMNGGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLSYIVSYYLRNFDED 1549
+L ++LA GNYMN + RG GF L L L D KS+D ++LL +Y+ N ++
Sbjct: 821 ILEIILALGNYMN--SSKRGAVYGFKLQSLDLLLDTKSTDRKQTLL-----HYISNVVKE 873
Query: 1550 AGKEQCLFPLPEPQDLFQASQMKFEDFQKDLRKLKKDLKACEVEAGKVYQVSSKEH-MQP 1608
+ LF E + +A+ + E+ D+++L++ + ++ +E+ M
Sbjct: 874 KYHQVSLF-YNELHYVEKAAAVSLENVLLDVKELQRGM-----------DLTKREYTMHD 921
Query: 1609 FKENMEQFIIQAKIDQEAEENSLTETHKCFLETTAYFFMKPKLGEKEVSPNAFFSIWHEF 1668
+++FI+ + + ++ F + YF P K P+ FF ++ F
Sbjct: 922 HNTLLKEFILNNEGKLKKLQDDAKIAQDAFDDVVKYFGENP----KTTPPSVFFPVFVRF 977
Query: 1669 SSDFK-----DFWKKENKLLLQERVKEAEEVCRQKKGKSLYKIKPRHDS 1712
+K + +K+ + L E++ E E + Q+ KS P H S
Sbjct: 978 VKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQDPKS-----PSHKS 1021
Score = 81.3 bits (199), Expect = 8e-15
Identities = 52/119 (43%), Positives = 58/119 (48%), Gaps = 34/119 (28%)
Query: 927 PGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGI 986
P G PLP PPPPPLP ++ P G P+ PP+P PPPPP
Sbjct: 516 PTMGAASSGPLP----PPPPPLPPSSDTPETVQNG---PVTPPMP----PPPPP------ 558
Query: 987 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIP 1042
PPPPP PPPPP PPPPPLPG +P PP P +P PPLPG P
Sbjct: 559 PPPPP------PPPPP------PPPPPLPGPAAETVPAPPLAPP--LPSAPPLPGTSSP 603
Score = 80.5 bits (197), Expect = 1e-14
Identities = 54/118 (45%), Positives = 55/118 (46%), Gaps = 32/118 (27%)
Query: 971 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1030
P G PLP PPPPPLP + P G PP PP P PPPPP P
Sbjct: 516 PTMGAASSGPLP----PPPPPLPPSSDTPETVQNGPVTPPMPPPP----PPPPPPP---- 563
Query: 1031 PPPPPLPGAGIPPPPPLPG--AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1086
PPPPP PPPPPLPG A P PPL PPLP A PPLPG P
Sbjct: 564 PPPPP------PPPPPLPGPAAETVPAPPLA-------PPLPSA-----PPLPGTSSP 603
Score = 80.5 bits (197), Expect = 1e-14
Identities = 54/118 (45%), Positives = 55/118 (46%), Gaps = 32/118 (27%)
Query: 982 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1041
P G PLP PPPPPLP + P G PP PP P PPPPP P
Sbjct: 516 PTMGAASSGPLP----PPPPPLPPSSDTPETVQNGPVTPPMPPPP----PPPPPPP---- 563
Query: 1042 PPPPPLPGAGIPPPPPLPG--AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1097
PPPPP PPPPPLPG A P PPL PPLP A PPLPG P
Sbjct: 564 PPPPP------PPPPPLPGPAAETVPAPPLA-------PPLPSA-----PPLPGTSSP 603
Score = 80.5 bits (197), Expect = 1e-14
Identities = 54/118 (45%), Positives = 55/118 (46%), Gaps = 32/118 (27%)
Query: 993 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1052
P G PLP PPPPPLP + P G PP PP P PPPPP P
Sbjct: 516 PTMGAASSGPLP----PPPPPLPPSSDTPETVQNGPVTPPMPPPP----PPPPPPP---- 563
Query: 1053 PPPPPLPGAGIPPPPPLPG--AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIP 1108
PPPPP PPPPPLPG A P PPL PPLP A PPLPG P
Sbjct: 564 PPPPP------PPPPPLPGPAAETVPAPPLA-------PPLPSA-----PPLPGTSSP 603
Score = 80.1 bits (196), Expect = 2e-14
Identities = 49/108 (45%), Positives = 52/108 (48%), Gaps = 23/108 (21%)
Query: 1015 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1074
P G PLP PPPPPLP + P G PP PP P PPPPP P
Sbjct: 516 PTMGAASSGPLP----PPPPPLPPSSDTPETVQNGPVTPPMPPPP----PPPPPPP---- 563
Query: 1075 PPPPPLPGAGIPPPPPLPGAG---IPPPPPLPGVGIPPPPPLPGAGIP 1119
PPPPP PPPPPLPG +P PP P +P PPLPG P
Sbjct: 564 PPPPP------PPPPPLPGPAAETVPAPPLAPP--LPSAPPLPGTSSP 603
Score = 80.1 bits (196), Expect = 2e-14
Identities = 49/108 (45%), Positives = 52/108 (48%), Gaps = 23/108 (21%)
Query: 1037 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1096
P G PLP PPPPPLP + P G PP PP P PPPPP P
Sbjct: 516 PTMGAASSGPLP----PPPPPLPPSSDTPETVQNGPVTPPMPPPP----PPPPPPP---- 563
Query: 1097 PPPPPLPGVGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIP 1141
PPPPP PPPPPLPG +P PP P +P PPLPG P
Sbjct: 564 PPPPP------PPPPPLPGPAAETVPAPPLAPP--LPSAPPLPGTSSP 603
Score = 80.1 bits (196), Expect = 2e-14
Identities = 49/108 (45%), Positives = 52/108 (48%), Gaps = 23/108 (21%)
Query: 1059 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGI 1118
P G PLP PPPPPLP + P G PP PP P PPPPP P
Sbjct: 516 PTMGAASSGPLP----PPPPPLPPSSDTPETVQNGPVTPPMPPPP----PPPPPPP---- 563
Query: 1119 PPPPPLPGAGIPPPPPLPGAG---IPPPPPLPRVGIPPPPPLPGAGIP 1163
PPPPP PPPPPLPG +P PP P +P PPLPG P
Sbjct: 564 PPPPP------PPPPPLPGPAAETVPAPPLAPP--LPSAPPLPGTSSP 603
Score = 80.1 bits (196), Expect = 2e-14
Identities = 52/119 (43%), Positives = 56/119 (47%), Gaps = 34/119 (28%)
Query: 1070 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGI 1129
P G PLP PPPPPLP + P G P PP+P PPPPP
Sbjct: 516 PTMGAASSGPLP----PPPPPLPPSSDTPETVQNG---PVTPPMP----PPPPP------ 558
Query: 1130 PPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGVGIP 1185
PPPPP PPPPP PPPPPLPG +P PP P +P PPLPG P
Sbjct: 559 PPPPP------PPPPP------PPPPPLPGPAAETVPAPPLAPP--LPSAPPLPGTSSP 603
Score = 80.1 bits (196), Expect = 2e-14
Identities = 49/108 (45%), Positives = 52/108 (48%), Gaps = 23/108 (21%)
Query: 1092 PGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGI 1151
P G PLP PPPPPLP + P G PP PP P PPPPP P
Sbjct: 516 PTMGAASSGPLP----PPPPPLPPSSDTPETVQNGPVTPPMPPPP----PPPPPPP---- 563
Query: 1152 PPPPPLPGAGIPPPPPLPGAG---IPPPPPLPGVGIPPPPPLPGVGIP 1196
PPPPP PPPPPLPG +P PP P +P PPLPG P
Sbjct: 564 PPPPP------PPPPPLPGPAAETVPAPPLAPP--LPSAPPLPGTSSP 603
Score = 79.7 bits (195), Expect = 2e-14
Identities = 49/108 (45%), Positives = 52/108 (48%), Gaps = 23/108 (21%)
Query: 960 PGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1019
P G PLP PPPPPLP + P G PP PP P PPPPP P
Sbjct: 516 PTMGAASSGPLP----PPPPPLPPSSDTPETVQNGPVTPPMPPPP----PPPPPPP---- 563
Query: 1020 PPPPPLPGAGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIP 1064
PPPPP PPPPPLPG +P PP P +P PPLPG P
Sbjct: 564 PPPPP------PPPPPLPGPAAETVPAPPLAPP--LPSAPPLPGTSSP 603
Score = 77.8 bits (190), Expect = 8e-14
Identities = 51/114 (44%), Positives = 56/114 (49%), Gaps = 34/114 (29%)
Query: 874 GMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILP 933
G +PPPPPPLP PS+ P+ +Q + PP PPP P PPPPP P
Sbjct: 524 GPLPPPPPPLP-------PSSDTPET--VQNGPVTPPMPPPPP----PPPPPPP------ 564
Query: 934 LPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIP 987
PP P PPPPPLPG A P PL PPLP A PPLPG P
Sbjct: 565 -PPPP----PPPPPLPGPAAETVP-----APPLAPPLPSA-----PPLPGTSSP 603
Score = 75.1 bits (183), Expect = 5e-13
Identities = 54/137 (39%), Positives = 57/137 (41%), Gaps = 44/137 (32%)
Query: 1038 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1097
G + P +G P PPPPPLP + P G PP PP P P
Sbjct: 511 GNSVGPTMGAASSGPLP---------PPPPPLPPSSDTPETVQNGPVTPPMPPPP----P 557
Query: 1098 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPL 1157
PPPP P PPPPP PPPPPLPG P A P PPL PPL
Sbjct: 558 PPPPPP----PPPPP------PPPPPLPG---------PAAETVPAPPL-------APPL 591
Query: 1158 PGAGIPPPPPLPGAGIP 1174
P A PPLPG P
Sbjct: 592 PSA-----PPLPGTSSP 603
Score = 72.8 bits (177), Expect = 3e-12
Identities = 50/124 (40%), Positives = 52/124 (41%), Gaps = 46/124 (37%)
Query: 908 LPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLP 967
LPPPPPPLP + P G P+PP P PPPPP PPPPP
Sbjct: 526 LPPPPPPLPPSSDTPETVQNGPVTPPMPPPP----PPPPP------PPPPP--------- 566
Query: 968 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1027
PPPPP PP P P A P PPL PPLP A PPLPG
Sbjct: 567 --------PPPPP-------PPLPGPAAETVPAPPL-------APPLPSA-----PPLPG 599
Query: 1028 AGIP 1031
P
Sbjct: 600 TSSP 603
Score = 69.7 bits (169), Expect = 2e-11
Identities = 47/112 (41%), Positives = 50/112 (44%), Gaps = 38/112 (33%)
Query: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915
P PPPLP + + G V PP PP P P PPP PPPPPP
Sbjct: 528 PPPPPLPPSSDTPETVQNGPVTPPMPPPP------------PPPPP-------PPPPPP- 567
Query: 916 PGAGIPPPPPLPG--AGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIP 965
PPPPPLPG A +P PPL PPLP A PPLPG P
Sbjct: 568 ----PPPPPPLPGPAAETVPAPPL-------APPLPSA-----PPLPGTSSP 603
Score = 55.8 bits (133), Expect = 3e-07
Identities = 72/292 (24%), Positives = 110/292 (37%), Gaps = 78/292 (26%)
Query: 638 LEDAETESQSAVSETPQKRSDAVQKEVVDMKSEGQATVIQQLEQTIEDLRTKIAELERQY 697
LEDAET++ + E V+ E + + ++L+ T + +KI ELE+Q
Sbjct: 382 LEDAETKNAAL--------------ERVEELEENISHLSEKLQDTENEAMSKIVELEKQL 427
Query: 698 PALDTEVASGHQGLENGVTASGDVCLEALRLEEKEVRHHRILEAK--------SIQTSPT 749
+ E+ + ++ T + + ++ +E+ ++ LE K +I+
Sbjct: 428 MQRNKELDVVREIYKDANTQVHTL-RKMVKEKEEAIQRQSTLEKKIHELEKQGTIKIQKK 486
Query: 750 EEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQ 809
+G + LP V SG S S +V+ + + + S
Sbjct: 487 GDGDIAILPVV-------------ASGT----LSMGSEVVAGNSVGPTMGA---ASSGPL 526
Query: 810 PPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSS 869
PPPPP L P S P ++ N P PP+P
Sbjct: 527 PPPPPPL-------PPSSDTPETVQ-------------------NGPVTPPMPPPPPPPP 560
Query: 870 MPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIP 921
P PPPPPPLPG T+P A P PPL P PPLPG P
Sbjct: 561 PPPPPPPPPPPPPLPGPAAETVP--APPLAPPL-------PSAPPLPGTSSP 603
Score = 37.4 bits (85), Expect = 0.13
Identities = 23/77 (29%), Positives = 30/77 (38%), Gaps = 1/77 (1%)
Query: 254 LGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPA 313
+GP+ GA + P L SD PE++ P P PP P P P P P
Sbjct: 514 VGPTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPP-PPPPPPPPPPPPPP 572
Query: 314 AKDSPSSTAFPFPEAGP 330
P++ P P P
Sbjct: 573 PLPGPAAETVPAPPLAP 589
>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
Length = 756
Score = 155 bits (391), Expect = 4e-37
Identities = 77/192 (40%), Positives = 92/192 (47%)
Query: 932 LPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPP 991
L LP + P PP + P PP + PP +G PP PP +G PP PP
Sbjct: 550 LALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPP 609
Query: 992 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1051
+G PP PP +G PP PP +G PP PP +G PP PP +G PP PP +G
Sbjct: 610 TGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSG 669
Query: 1052 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP 1111
PP PP AG PP PP +G PP PP +G PP P + P PP G PP P
Sbjct: 670 APPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVP 729
Query: 1112 PLPGAGIPPPPP 1123
P + P PP
Sbjct: 730 PTGDSEAAPVPP 741
Score = 154 bits (389), Expect = 7e-37
Identities = 75/180 (41%), Positives = 88/180 (48%)
Query: 977 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1036
P PP + P PP + P PP +G PP PP +G PP PP +G PP PP
Sbjct: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
Query: 1037 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1096
+G PP PP +G PP PP +G PP PP +G PP PP +G PP PP AG
Sbjct: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP 681
Query: 1097 PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPP 1156
PP PP G PP PP +G PP P + P PP +G PP PP P PP
Sbjct: 682 PPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
Score = 154 bits (389), Expect = 7e-37
Identities = 75/180 (41%), Positives = 88/180 (48%)
Query: 999 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1058
P PP + P PP + P PP +G PP PP +G PP PP +G PP PP
Sbjct: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
Query: 1059 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGI 1118
+G PP PP +G PP PP +G PP PP +G PP PP G PP PP AG
Sbjct: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP 681
Query: 1119 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1178
PP PP +G PP PP +G PP P P PP +G PP PP + P PP
Sbjct: 682 PPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
Score = 154 bits (388), Expect = 9e-37
Identities = 74/180 (41%), Positives = 88/180 (48%)
Query: 988 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1047
P PP + P PP + P PP +G PP PP +G PP PP +G PP PP
Sbjct: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
Query: 1048 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGI 1107
+G PP PP +G PP PP +G PP PP +G PP PP +G PP PP G
Sbjct: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP 681
Query: 1108 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPP 1167
PP PP +G PP PP +G PP P + P PP G PP PP + P PP
Sbjct: 682 PPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
Score = 154 bits (388), Expect = 9e-37
Identities = 74/178 (41%), Positives = 88/178 (49%)
Query: 968 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1027
PP + P PP + P PP +G PP PP +G PP PP +G PP PP
Sbjct: 564 PPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGD 623
Query: 1028 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1087
+G PP PP +G PP PP +G PP PP +G PP PP +G PP PP AG PP
Sbjct: 624 SGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPP 683
Query: 1088 PPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1145
PP +G PP PP G PP P + P PP +G PP PP + P PP
Sbjct: 684 VPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
Score = 153 bits (386), Expect = 2e-36
Identities = 76/183 (41%), Positives = 90/183 (49%), Gaps = 1/183 (0%)
Query: 952 AIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1011
A P PP P+PP + P PP +G PP PP +G PP PP +G PP
Sbjct: 560 ATPVPPTGDSEATPVPPT-GDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPV 618
Query: 1012 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1071
PP +G PP PP +G PP PP +G PP PP +G PP PP +G PP PP
Sbjct: 619 PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGD 678
Query: 1072 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPP 1131
AG PP PP +G PP PP +G PP P P PP +G PP PP + P
Sbjct: 679 AGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAP 738
Query: 1132 PPP 1134
PP
Sbjct: 739 VPP 741
Score = 153 bits (386), Expect = 2e-36
Identities = 75/180 (41%), Positives = 87/180 (48%)
Query: 1010 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1069
P PP + P PP + P PP +G PP PP +G PP PP +G PP PP
Sbjct: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
Query: 1070 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGI 1129
+G PP PP +G PP PP +G PP PP G PP PP +G PP PP AG
Sbjct: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP 681
Query: 1130 PPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP 1189
PP PP +G PP PP G PP P + P PP +G PP PP P PP
Sbjct: 682 PPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
Score = 152 bits (385), Expect = 2e-36
Identities = 74/186 (39%), Positives = 91/186 (48%)
Query: 905 TEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGI 964
T+ P PP + P PP + P+PP +G PP PP + PP PP +G
Sbjct: 556 TDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGA 615
Query: 965 PLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1024
P PP +G PP PP +G PP PP +G PP PP +G PP PP +G PP PP
Sbjct: 616 PPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPP 675
Query: 1025 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1084
AG PP PP +G PP PP +G PP P + P PP +G PP PP +
Sbjct: 676 TGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSE 735
Query: 1085 IPPPPP 1090
P PP
Sbjct: 736 AAPVPP 741
Score = 152 bits (383), Expect = 4e-36
Identities = 73/180 (40%), Positives = 89/180 (49%)
Query: 922 PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPL 981
P PP + P+PP + P PP + PP PP +G P PP +G PP PP
Sbjct: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
Query: 982 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1041
+G PP PP +G PP PP +G PP PP +G PP PP +G PP PP AG
Sbjct: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP 681
Query: 1042 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1101
PP PP +G PP PP +G PP P + P PP +G PP PP + P PP
Sbjct: 682 PPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
Score = 152 bits (383), Expect = 4e-36
Identities = 75/180 (41%), Positives = 86/180 (47%)
Query: 1021 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1080
P PP + P PP + P PP +G PP PP +G PP PP +G PP PP
Sbjct: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
Query: 1081 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1140
+G PP PP +G PP PP G PP PP +G PP PP +G PP PP AG
Sbjct: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP 681
Query: 1141 PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP 1200
PP PP G PP PP +G PP P + P PP G PP PP P PP
Sbjct: 682 PPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
Score = 151 bits (382), Expect = 5e-36
Identities = 74/180 (41%), Positives = 86/180 (47%)
Query: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1091
P PP + P PP + P PP +G PP PP +G PP PP +G PP PP
Sbjct: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
Query: 1092 PGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGI 1151
+G PP PP G PP PP +G PP PP +G PP PP +G PP PP G
Sbjct: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP 681
Query: 1152 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPP 1211
PP PP +G PP PP +G PP P P PP G PP PP + P PP
Sbjct: 682 PPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
Score = 149 bits (376), Expect = 2e-35
Identities = 74/179 (41%), Positives = 84/179 (46%)
Query: 1043 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1102
P PP + P PP + P PP +G PP PP +G PP PP +G PP PP
Sbjct: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
Query: 1103 PGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGI 1162
G PP PP +G PP PP +G PP PP +G PP PP G PP PP AG
Sbjct: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP 681
Query: 1163 PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAP 1221
PP PP +G PP PP G PP P P PP +G PP PP P P
Sbjct: 682 PPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVP 740
Score = 144 bits (364), Expect = 6e-34
Identities = 75/195 (38%), Positives = 94/195 (48%), Gaps = 4/195 (2%)
Query: 886 MTVPTLPST-AIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPP 944
+ +PT+ A P PP + P PP + P PP +G P+PP +G PP
Sbjct: 550 LALPTVTDQEATPVPPT---GDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPP 606
Query: 945 PPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1004
PP + PP PP +G P PP +G PP PP +G PP PP +G PP PP
Sbjct: 607 VPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTG 666
Query: 1005 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1064
+G PP PP AG PP PP +G PP PP +G PP P + P PP +G P
Sbjct: 667 DSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAP 726
Query: 1065 PPPPLPGAGIPPPPP 1079
P PP + P PP
Sbjct: 727 PVPPTGDSEAAPVPP 741
Score = 142 bits (357), Expect = 4e-33
Identities = 76/181 (41%), Positives = 86/181 (47%), Gaps = 8/181 (4%)
Query: 1054 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL 1113
P PP + P PP + P PP +G PP PP +G PP PP G PP PP
Sbjct: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
Query: 1114 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPG-AG 1172
+G PP PP +G PP PP +G PP PP G PP PP +G PP PP G AG
Sbjct: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT-GDAG 680
Query: 1173 IPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAP------APPLP 1226
PP PP G PP PP G PP P + P PP G PP P A P+P
Sbjct: 681 PPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVP 740
Query: 1227 P 1227
P
Sbjct: 741 P 741
Score = 135 bits (341), Expect = 3e-31
Identities = 77/200 (38%), Positives = 92/200 (46%), Gaps = 7/200 (3%)
Query: 1065 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL 1124
P PP + P PP + P PP +G PP PP G PP PP +G PP PP
Sbjct: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
Query: 1125 PGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGI 1184
+G PP PP +G PP PP G PP PP +G PP PP +G PP PP G
Sbjct: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPP---TGD 678
Query: 1185 PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPG-TGIPP-PPLLPVSG 1242
PPP+P G PP+P G PP+ G + P+PP G +G PP PP
Sbjct: 679 AGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTG--DSETAPVPPTGDSGAPPVPPTGDSEA 736
Query: 1243 PPLLPQVGSSTLPTPQVCGF 1262
P+ P S P V F
Sbjct: 737 APVPPTDDSKEAQMPAVIRF 756
Score = 135 bits (339), Expect = 4e-31
Identities = 74/197 (37%), Positives = 89/197 (45%), Gaps = 7/197 (3%)
Query: 861 LPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGI 920
LP + P VPP PT S P PP + PP PP +G
Sbjct: 552 LPTVTDQEATP----VPPTGDSEATPVPPTGDSETAPVPPT---GDSGAPPVPPTGDSGA 604
Query: 921 PPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPP 980
PP PP +G P+PP +G PP PP + PP PP +G P PP +G PP PP
Sbjct: 605 PPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPP 664
Query: 981 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1040
+G PP PP AG PP PP +G PP PP +G PP P + P PP +G
Sbjct: 665 TGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSG 724
Query: 1041 IPPPPPLPGAGIPPPPP 1057
PP PP + P PP
Sbjct: 725 APPVPPTGDSEAAPVPP 741
Score = 132 bits (333), Expect = 2e-30
Identities = 72/182 (39%), Positives = 81/182 (44%), Gaps = 14/182 (7%)
Query: 1087 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1146
P PP + P PP P PP +G PP PP +G PP PP +G PP PP
Sbjct: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
Query: 1147 PRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGI 1206
G PP PP +G PP PP +G PP PP G PP PP G PP PP AG
Sbjct: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP 681
Query: 1207 PPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPP 1266
PP PP G APP+PP G PP+ P S T P P PP
Sbjct: 682 PPVPPTGDSG-----APPVPPTGDS---------GAPPVTPTGDSETAPVPPTGDSGAPP 727
Query: 1267 LP 1268
+P
Sbjct: 728 VP 729
Score = 129 bits (324), Expect = 2e-29
Identities = 72/187 (38%), Positives = 87/187 (46%), Gaps = 7/187 (3%)
Query: 860 PLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAG 919
P+P T S + P VPP PT S A P PP + PP PP +G
Sbjct: 562 PVPPTGDSEATP----VPPTGDSETAPVPPTGDSGAPPVPPT---GDSGAPPVPPTGDSG 614
Query: 920 IPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPP 979
PP PP +G P+PP +G PP PP + PP PP +G P PP +G PP P
Sbjct: 615 APPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVP 674
Query: 980 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1039
P AG PP PP +G PP PP +G PP P + P PP +G PP PP +
Sbjct: 675 PTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDS 734
Query: 1040 GIPPPPP 1046
P PP
Sbjct: 735 EAAPVPP 741
Score = 107 bits (266), Expect = 1e-22
Identities = 62/168 (36%), Positives = 78/168 (46%), Gaps = 3/168 (1%)
Query: 859 PPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGT-EMLPPPPPPLPG 917
PP +E++ P PP PP P +P T PP+ T + PP PP
Sbjct: 575 PPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGD 634
Query: 918 AGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG-AGIPLPPPLPGAGIP 976
+G PP PP +G P+PP +G PP PP + PP PP G AG P PP +G P
Sbjct: 635 SGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT-GDAGPPPVPPTGDSGAP 693
Query: 977 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1024
P PP +G PP P + P PP +G PP PP + P PP
Sbjct: 694 PVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
Score = 75.5 bits (184), Expect = 4e-13
Identities = 67/252 (26%), Positives = 87/252 (34%), Gaps = 78/252 (30%)
Query: 740 EAKSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLD 799
++++ PT + +PP G G PP PP +SG
Sbjct: 568 DSEATPVPPTGDSETAPVPPT-GDSGAPPVPPTGDSGAPPV------------------- 607
Query: 800 SHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPP 859
PT PP PP+ G G+ P
Sbjct: 608 --PPTGDSGAPPVPPT-------GDSGA-------------------------------P 627
Query: 860 PLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAG 919
P+P T S + PP+P PT S A P PP + PP PP +G
Sbjct: 628 PVPPTGDSGA-----------PPVP----PTGDSGAPPVPPT---GDSGAPPVPPTGDSG 669
Query: 920 IPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPP 979
PP PP AG P+PP +G PP PP + PP P + PP +G PP P
Sbjct: 670 APPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVP 729
Query: 980 PLPGAGIPPPPP 991
P + P PP
Sbjct: 730 PTGDSEAAPVPP 741
Score = 49.3 bits (116), Expect = 3e-05
Identities = 36/101 (35%), Positives = 43/101 (42%), Gaps = 11/101 (10%)
Query: 1179 LPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMG---IPPAP------APPLPPPG 1229
LP V P+P G P+P G P+P G PP P APP+PP G
Sbjct: 552 LPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTG 611
Query: 1230 -TGIPPPPLLPVSGPPLLPQVG-SSTLPTPQVCGFLPPPLP 1268
+G PP P SG P +P G S P P PP+P
Sbjct: 612 DSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVP 652
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 155 bits (391), Expect = 4e-37
Identities = 118/302 (39%), Positives = 141/302 (46%), Gaps = 67/302 (22%)
Query: 877 PPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPP 936
PP PP LP P P PP + G PP PPLP + +PPPPP G LPLPP
Sbjct: 217 PPAPPSLPAGP----PGVKRPPPPLMNGL----PPRPPLPES-LPPPPP----GGLPLPP 263
Query: 937 LPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPL---PGAGIPPPPPLPGAGIPPPPPLP 993
+P G P P PG PP P P G+ P P+ P +G+ PP P G+ PP P
Sbjct: 264 MPPTG-PAPSGPPG---PPQLPPPAPGVHPPAPVVHPPASGVHPPAP----GVHPPAP-- 313
Query: 994 GAGIPPPPP---LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1050
G+ PP P P +G+ PP P G+ PP P G+ PP P G+ PP P
Sbjct: 314 --GVHPPAPGVHPPTSGVHPPAP----GVHPPAP----GVHPPAP----GVHPPAP---- 355
Query: 1051 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPP---PPLPGVG 1106
G+ PP P G+ PP P AG+ P P P P PG P P P PGV
Sbjct: 356 GVHPPAP----GVHPP---PSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVH 408
Query: 1107 IPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPP 1165
PP P A G+ P PP G+ P P G+ PP P+P + PP P IPPP
Sbjct: 409 PQPPGVHPSAPGVHPQPP----GVHPSNP----GVHPPTPMPPMLRPPLPSEGPGNIPPP 460
Query: 1166 PP 1167
PP
Sbjct: 461 PP 462
Score = 154 bits (389), Expect = 7e-37
Identities = 118/289 (40%), Positives = 141/289 (48%), Gaps = 62/289 (21%)
Query: 909 PPPPPPLPGAGIP----PPPPLPGAGILPLPPLPGAGIPPPPP--LPGAAIPPPPPLPGA 962
PP PP LP AG P PPPPL G+ P PPLP + +PPPPP LP +PP P P +
Sbjct: 217 PPAPPSLP-AGPPGVKRPPPPLMN-GLPPRPPLPES-LPPPPPGGLPLPPMPPTGPAP-S 272
Query: 963 GIPLPP--PLPGAGIPPPPPL---PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP---L 1014
G P PP P P G+ PP P+ P +G+ PP P G+ PP P G+ PP P
Sbjct: 273 GPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAP----GVHPPAP----GVHPPAPGVHP 324
Query: 1015 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1074
P +G+ PP P G+ PP P G+ PP P G+ PP P G+ PP P G+
Sbjct: 325 PTSGVHPPAP----GVHPPAP----GVHPPAP----GVHPPAP----GVHPPAP----GV 364
Query: 1075 PPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGVGIPPP---PPLPGAGIPPPPPLPGA-GI 1129
PP P AG+ P P P P PGV P P P PG PP P A G+
Sbjct: 365 HPP---PSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGV 421
Query: 1130 PPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1178
P PP G+ P P G+ PP P+P PP P IPPPPP
Sbjct: 422 HPQPP----GVHPSNP----GVHPPTPMPPMLRPPLPSEGPGNIPPPPP 462
Score = 150 bits (378), Expect = 1e-35
Identities = 112/269 (41%), Positives = 129/269 (47%), Gaps = 56/269 (20%)
Query: 976 PPPPPLPGAGIP----PPPPLPGAGIPPPPPLPGAGIPPPPP--LPGAGIPPPPPLPGAG 1029
PP PP AG P PPPPL G+PP PPLP + +PPPPP LP +PP P P +G
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMN-GLPPRPPLPES-LPPPPPGGLPLPPMPPTGPAP-SG 273
Query: 1030 IPPPP--PLPGAGIPPPPPL---PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1084
P PP P P G+ PP P+ P +G+ PP P G+ PP P G+ PP P G
Sbjct: 274 PPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAP----GVHPPAP----GVHPPAP----G 321
Query: 1085 IPPP-----PPLPGAGIPPP---PPLPGVGIPPP---PPLPGAGIPPP----PPLPGAGI 1129
+ PP PP PG P P PP PGV P P PP PG PP P PG
Sbjct: 322 VHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHP 381
Query: 1130 PPP---PPLPGAGIPPP---PPLPRVGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGV 1182
P P PG P P P P V PP P A G+ P PP G+ P P
Sbjct: 382 AAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPP----GVHPSNP---- 433
Query: 1183 GIPPPPPLPGVGIPPPPPLPGAGIPPPPP 1211
G+ PP P+P + PP P IPPPPP
Sbjct: 434 GVHPPTPMPPMLRPPLPSEGPGNIPPPPP 462
Score = 146 bits (369), Expect = 1e-34
Identities = 115/281 (40%), Positives = 131/281 (46%), Gaps = 67/281 (23%)
Query: 987 PPPPPLPGAGIP----PPPPLPGAGIPPPPPLPGAGIPPPPP--LPGAGIPPPPPLPGAG 1040
PP PP AG P PPPPL G+PP PPLP + +PPPPP LP +PP P P +G
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMN-GLPPRPPLPES-LPPPPPGGLPLPPMPPTGPAP-SG 273
Query: 1041 IPPPP--PLPGAGIPPPPPL---PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1095
P PP P P G+ PP P+ P +G+ PP P G+ PP P G+ PP P G
Sbjct: 274 PPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAP----GVHPPAP----GVHPPAP----G 321
Query: 1096 IPPP-----PPLPGVGIPPP---PPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPP 1144
+ PP PP PGV P P PP PG P P PP PG + PPP AG+ P
Sbjct: 322 VHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPG--VHPPP---SAGVHPQA 376
Query: 1145 PLPRVGIPPP-PPLPGAGIPPP---PPLPGAGIPPP---PPLPGVGIPPPPPLPG-VGIP 1196
P P P PG P P P PG PP P PGV PP P G+
Sbjct: 377 PGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVH 436
Query: 1197 PPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTG-IPPPP 1236
PP P+ PP PPLP G G IPPPP
Sbjct: 437 PPTPM----------------PPMLRPPLPSEGPGNIPPPP 461
Score = 139 bits (349), Expect = 3e-32
Identities = 106/260 (40%), Positives = 124/260 (47%), Gaps = 49/260 (18%)
Query: 1031 PPPPPLPGAGIP----PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1086
PP PP AG P PPPPL G+PP PPLP + +PPPPP G P PP+P G P
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMN-GLPPRPPLPES-LPPPPP----GGLPLPPMPPTG-P 269
Query: 1087 PPPPLPGAGIPPPPPLPGVGIPPPPPL---PGAGIPPPPP---LPGAGIPPPPP---LPG 1137
P PG PP P P G+ PP P+ P +G+ PP P P G+ PP P P
Sbjct: 270 APSGPPG---PPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPT 326
Query: 1138 AGIPPPPPLPRVGIPPP-----PPLPGAGIPPP---PPLPGAGIPPP----PPLPGVGIP 1185
+G+ PP P G+ PP PP PG P P PP PG PP P PGV
Sbjct: 327 SGVHPPAP----GVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPA 382
Query: 1186 PP---PPLPGVGIPPP---PPLPGAGIPPPPPLPGM-GIPPAPAPPLPPPGTGI-PPPPL 1237
P P PGV P P P PG PP P G+ P P P + P G+ PP P+
Sbjct: 383 APAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQP-PGVHPSNPGVHPPTPM 441
Query: 1238 LPVSGPPLLPQVGSSTLPTP 1257
P+ PP LP G +P P
Sbjct: 442 PPMLRPP-LPSEGPGNIPPP 460
Score = 107 bits (266), Expect = 1e-22
Identities = 96/288 (33%), Positives = 114/288 (39%), Gaps = 54/288 (18%)
Query: 807 ISQPPPPPSLLWSAGQGQPG-SQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTE 865
+ +PP PPSL G PG +PP + S +P PP P
Sbjct: 214 MEKPPAPPSL----PAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGP 269
Query: 866 SSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPP---PPLPGAGIPP 922
+ S PG +PPP P + P + PP + + PP P PP PG P
Sbjct: 270 APSGPPGPPQLPPPAPGVH-------PPAPVVHPP---ASGVHPPAPGVHPPAPGVHPPA 319
Query: 923 P---PPLPGAGILPLPPLPGAGIPPP---PPLPGAAIPPP---PPLPGAGIPLPPPLPGA 973
P PP G PP PG P P PP PG P P PP PG P P A
Sbjct: 320 PGVHPPTSGVH----PPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGV-----HPPPSA 370
Query: 974 GIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIP 1031
G+ P P P P PG P P P A G+ P PP G+ P P G+
Sbjct: 371 GVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPP----GVHPSAP----GVH 422
Query: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1079
P PP G+ P P G+ PP P+P PP P IPPPPP
Sbjct: 423 PQPP----GVHPSNP----GVHPPTPMPPMLRPPLPSEGPGNIPPPPP 462
Score = 94.0 bits (232), Expect = 1e-18
Identities = 103/338 (30%), Positives = 124/338 (36%), Gaps = 101/338 (29%)
Query: 735 HHRILEAKSIQTSPTEEGGVLTLPP--VDGLPGRPPCPPGAESGPQTKFCSEISLIVSPR 792
H ++ + + + P GV PP ++GLP RPP P ES P
Sbjct: 211 HFKMEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLP---ESLPP-------------- 253
Query: 793 RISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNS 852
P + PP PP+ +G P PP
Sbjct: 254 ---------PPPGGLPLPPMPPTGPAPSGPPGPPQLPP---------------------- 282
Query: 853 CNIPSP---PPLPCTESSSSMPGLGMVPPPP---PPLPGMTVPTLPSTAIPQPPPLQGTE 906
P+P PP P P G+ PP P PP PG+ P A PP G
Sbjct: 283 ---PAPGVHPPAPVVHP----PASGVHPPAPGVHPPAPGVHPP-----APGVHPPTSGVH 330
Query: 907 MLPPPP---PPLPGAGIPPP---PPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLP 960
PP P PP PG P P PP PG PP PG PPP G P P +
Sbjct: 331 --PPAPGVHPPAPGVHPPAPGVHPPAPGVH----PPAPGV---HPPPSAGVH-PQAPGVH 380
Query: 961 GAGIPLPPPLPGAGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1019
A + P PG P P P A G+ P PP G+ P P G+ P PP G+
Sbjct: 381 PAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPP----GVHPSAP----GVHPQPP----GV 428
Query: 1020 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1057
P P G+ PP P+P PP P IPPPPP
Sbjct: 429 HPSNP----GVHPPTPMPPMLRPPLPSEGPGNIPPPPP 462
Score = 93.6 bits (231), Expect = 1e-18
Identities = 71/171 (41%), Positives = 84/171 (49%), Gaps = 31/171 (18%)
Query: 1108 PPPPPLPGAGIP----PPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIP 1163
PP PP AG P PPPPL G+PP PPLP + +PPPPP G P PP+P G
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMN-GLPPRPPLPES-LPPPPP----GGLPLPPMPPTGPA 270
Query: 1164 PPPPLPGAGIPPPPPLPGVGIPPPPPL---PGVGIPPPPPLPGAGIPPPPPLPGMGIPPA 1220
P P PG PP P P G+ PP P+ P G+ PP P G+ PP P G+ P
Sbjct: 271 PSGP-PG---PPQLPPPAPGVHPPAPVVHPPASGVHPPAP----GVHPPAP----GVHP- 317
Query: 1221 PAPPLPPPGTG-IPPPPLLPVSGPPLLPQVGSSTLPTPQV----CGFLPPP 1266
PAP + PP +G PP P + P + P P P V G PPP
Sbjct: 318 PAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPP 368
Score = 49.7 bits (117), Expect = 2e-05
Identities = 35/89 (39%), Positives = 40/89 (44%), Gaps = 25/89 (28%)
Query: 1185 PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGM-GIPPAPAPPLPPPGTGIPPPPLLPV--- 1240
PP PP +P PP G PPPP + G+ PP P PPP G+P PP+ P
Sbjct: 217 PPAPP----SLPAGPP--GVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPA 270
Query: 1241 -SGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
SGPP PQ LPPP P
Sbjct: 271 PSGPPGPPQ--------------LPPPAP 285
Score = 40.4 bits (93), Expect = 0.015
Identities = 52/190 (27%), Positives = 59/190 (31%), Gaps = 48/190 (25%)
Query: 230 EEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPRE 289
E+P APP+ P+G G P L LPESL
Sbjct: 215 EKPPAPPSL-----------------PAGPPGVKRPPPPLMNGLPPRPPLPESLP----- 252
Query: 290 PQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAG--PGEEAAGAPVRGAGDTDE 347
PP PGGLP+ P +P PA P P P G P P G
Sbjct: 253 ---PPPPGGLPL---PPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASG------ 300
Query: 348 EGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAA-ASLPGSPAPSQR 406
AP P AP V AP G P P AP PG P+
Sbjct: 301 -----VHPPAPGVHPP---APGVHPPAP---GVHPPTSGVHPPAPGVHPPAPGVHPPAPG 349
Query: 407 CFKPYPLITP 416
P P + P
Sbjct: 350 VHPPAPGVHP 359
Score = 38.5 bits (88), Expect = 0.057
Identities = 26/56 (46%), Positives = 29/56 (51%), Gaps = 15/56 (26%)
Query: 1218 PPAPAPPLP--PPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGL 1271
PPAP P LP PPG PPPPL+ +G P P P + LPPP P GL
Sbjct: 217 PPAP-PSLPAGPPGVKRPPPPLM--NGLP----------PRPPLPESLPPPPPGGL 259
Score = 37.4 bits (85), Expect = 0.13
Identities = 59/230 (25%), Positives = 70/230 (30%), Gaps = 24/230 (10%)
Query: 232 PAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQ 291
P P + P PG GL + P+G A P P + P + P
Sbjct: 245 PPLPESLPPPPPG---GLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGV 301
Query: 292 QPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEE 351
PP+PG P AP + P S P P P P G
Sbjct: 302 HPPAPGVHP--PAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHP 359
Query: 352 DAFEDAPRGSPG-EEWAPEVGEDAP----QRLGEEPEEEAQGPDAPAAASLPGSPAPSQR 406
A P S G AP V AP Q G P P AP P PS
Sbjct: 360 PAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAP 419
Query: 407 CFKPYPL-ITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGS 455
P P + P S+P P P P + R P PS G+
Sbjct: 420 GVHPQPPGVHP----------SNPGVHP---PTPMPPMLRPPLPSEGPGN 456
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 154 bits (388), Expect = 9e-37
Identities = 133/429 (31%), Positives = 150/429 (34%), Gaps = 63/429 (14%)
Query: 886 MTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPP 945
+T P+ P+T P PPP T + P P P PPP P PP+ PPP
Sbjct: 1396 ITTPSPPTTT-PSPPPTSTTTLPPTTTPSPPTTTTTTPPPTT----TPSPPITTTTTPPP 1450
Query: 946 -----PPLPGAAIPPP--PPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPP--PPLPGAG 996
PP+ PPP P P P PP P PP PPP P P
Sbjct: 1451 TTTPSPPISTTTTPPPTTTPSPPTTTPSPPT-----TTPSPPTTTTTTPPPTTTPSPPTT 1505
Query: 997 IPPPPPLPGAGIP----PPPPLPGAGIPPP--PPLPGAGIPPPPPLPGAGIPP---PPPL 1047
P PP +P P PP PPP P P P PP +PP P P
Sbjct: 1506 TPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP 1565
Query: 1048 PGAGIPPPP---PLPGAGIPPPPPLPGAGIPPP-----PPLPGAGIPPP--PPLPGAGIP 1097
P PPP P P P PP PPP PP PPP P P P
Sbjct: 1566 PTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1625
Query: 1098 PPPPLPGVGIPP---PPPLPGAGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPR--V 1149
PP +PP P P P PPP P P P PP+ PPP P +
Sbjct: 1626 ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPI 1685
Query: 1150 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP----LPGVGIPPPPPLPGAG 1205
P PP P P P + I P PPP P P PP
Sbjct: 1686 TTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMT 1745
Query: 1206 IPPP----PPLPGMGIPPAPAPP-LPPPGTGIPPPPLLPV--------SGPPLLPQVGSS 1252
PP PL +PP+ PP P T P P +P+ SG P + G
Sbjct: 1746 TLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGD 1805
Query: 1253 TLPTPQVCG 1261
T VCG
Sbjct: 1806 TELIGDVCG 1814
Score = 134 bits (338), Expect = 6e-31
Identities = 112/363 (30%), Positives = 124/363 (34%), Gaps = 53/363 (14%)
Query: 936 PLPGAGIPPPPPLPGAAIPPP--PPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLP 993
P P P PPP +PP P P PPP P PP+ PPP P
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTT----TPSPPITTTTTPPPTTTP 1454
Query: 994 GAGIPPPPPLPGAGIPPPP--PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP--PLPG 1049
PP+ PPP P P P PP P PP PPP P P
Sbjct: 1455 S------PPISTTTTPPPTTTPSPPTTTPSPPTTT-----PSPPTTTTTTPPPTTTPSPP 1503
Query: 1050 AGIPPPPPLPGAGIPPP----PPLPGAGIPPPP--PLPGAGIPPPPPLPGAGIPP---PP 1100
P PP +PP PP PPP P P P PP +PP P
Sbjct: 1504 TTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1563
Query: 1101 PLPGVGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPP-- 1155
P P PPP P P P PP PPP P PP PPP
Sbjct: 1564 PPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPS------PPTTTTTTPPPTTT 1617
Query: 1156 PLPGAGIPPPPPLPGAGIPP---PPPLPGVGIPPPP---PLPGVGIPPPPPLPGAGIPPP 1209
P P P PP +PP P P P PPP P P P PP+ PPP
Sbjct: 1618 PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPP 1677
Query: 1210 PPLPGMGIPPAPAPPLP----PPGTGIPPPPLLPVSGPP--LLPQVGSSTLPTPQVCGFL 1263
P I P+PP P T P P+ + P P +T+ TP
Sbjct: 1678 TTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTP 1737
Query: 1264 PPP 1266
PP
Sbjct: 1738 SPP 1740
Score = 108 bits (270), Expect = 4e-23
Identities = 107/395 (27%), Positives = 132/395 (33%), Gaps = 51/395 (12%)
Query: 768 PCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQP-----PPPPSLLWSAGQ 822
P PP P + + +P + + PT + S P PPP+ S
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458
Query: 823 GQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPL-----PCTESSSSMPGLGMVP 877
+ PP + + T+ ++ + +PPP P T + +P
Sbjct: 1459 STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLP 1518
Query: 878 P---PPPPLPGMTVPTLPSTAIPQPP------PLQGTEMLPP---PPPPLPGAGIPPP-- 923
P P PP T P P T P PP P T LPP P PP PPP
Sbjct: 1519 PTTTPSPPTTTTTTP--PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT 1576
Query: 924 PPLPGAGILPLPPLPGAGIPPP-----PPLPGAAIPPP--PPLPGAGIPLPPPLPGAGIP 976
P P P PP PPP PP PPP P P P+ PP +P
Sbjct: 1577 TPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP 1636
Query: 977 P---PPPLPGAGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGAGI--PPPPPLPGA 1028
P P P P PPP P P P PP+ PPP P + I P PP
Sbjct: 1637 PTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTM 1696
Query: 1029 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1088
P P P + I P PPP + P P P PP +PP
Sbjct: 1697 TTPSPTTTPSSPITTTTTPSSTTTPSPPP---TTMTTPSP---TTTPSPPTTTMTTLPPT 1750
Query: 1089 PPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPP 1123
P PP I PP P + P P
Sbjct: 1751 TTSSPLTTTPLPP----SITPPTFSPFSTTTPTTP 1781
Score = 107 bits (267), Expect = 1e-22
Identities = 129/552 (23%), Positives = 171/552 (30%), Gaps = 63/552 (11%)
Query: 768 PCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGS 827
P P G ++ T + ++ +P Q + P + + P P+ G P +
Sbjct: 3774 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---PTGTQTPTT 3830
Query: 828 QPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPG-LGMVPPPPPPLPGM 886
P + +T T + P+ P+ T + + P G P P+
Sbjct: 3831 TPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3882
Query: 887 TV----PTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAG-ILPLPPLPGAG 941
T PT T P P+ T + P P P G P P+ + P P G
Sbjct: 3883 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQ 3941
Query: 942 IPPPPPLPGAAIPPPPPLP-GAGIPLPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIPP 999
P P+ P P P G P P+ P P P G P P+
Sbjct: 3942 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4001
Query: 1000 PPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPP 1056
P P P G P P+ P P P G P P+ P P P G P
Sbjct: 4002 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4061
Query: 1057 PLPGAGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGVGIPPPPPLP 1114
P+ P P P G P P+ P P P G P P+ P P P
Sbjct: 4062 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4121
Query: 1115 -GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPRVGIPPPPPLP-GAGIPPPPPLPGA 1171
G P P+ P P P G P P+ P P P G P P+
Sbjct: 4122 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4181
Query: 1172 GIPPPPPLP-GVGIPPPP-----PLPGVGIPPPPPLPG-------------------AGI 1206
P P P G PP P+ + PPP + +
Sbjct: 4182 TTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTL 4241
Query: 1207 PPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQ----VGSSTLPTPQ---- 1258
PP + P P P G PP + PP P GSS+ PTP
Sbjct: 4242 PPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQT 4301
Query: 1259 --VCGFLPPPLP 1268
+ P P P
Sbjct: 4302 TTTSAWTPTPTP 4313
Score = 102 bits (254), Expect = 3e-21
Identities = 125/542 (23%), Positives = 170/542 (31%), Gaps = 48/542 (8%)
Query: 768 PCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGS 827
P P G ++ T + ++ +P Q + P + + P P+ G P +
Sbjct: 2164 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---PTGTQTPTT 2220
Query: 828 QPPHSISTEFQT-----SHEHSVSSAFKNSCNIPSPPPL----PCTESSSSMPGLGMVPP 878
P + +T T + + + + P+P P P T ++ + P
Sbjct: 2221 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2280
Query: 879 PPPPLPGMTVPTLPSTAI-----------PQPPPLQGTEMLPPPPPPLPGAGIPPPPPL- 926
P T P +T + P P+ T + P P P G P P+
Sbjct: 2281 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPIT 2339
Query: 927 PGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLP-GAGIPLPPPLPGAGIPPPPPLP-GA 984
+ P P G P P+ P P P G P P+ P P P G
Sbjct: 2340 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2399
Query: 985 GIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIP 1042
P P+ P P P G P P+ P P P G P P+
Sbjct: 2400 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2459
Query: 1043 PPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPP 1099
P P P G P P+ P P P G P P+ P P P G P
Sbjct: 2460 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2519
Query: 1100 PPLPGVGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPRVGIPPPPPL 1157
P+ P P P G P P+ P P P G P P+ P P
Sbjct: 2520 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2579
Query: 1158 P-GAGIPPPPPLPGAGIPPPPPLP-GVGIPPPPPLPGVGIPPPPPLP-GAGIPPPPPL-P 1213
P G P P+ P P P G P P+ P P P G P P+
Sbjct: 2580 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2639
Query: 1214 GMGIPPAPAP---------PLPPPGTGIPPPPLLPVSGPPLLPQVGSSTL-PTPQVCGFL 1263
+ P P P P+ T P P P P ++T+ PTP G
Sbjct: 2640 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2699
Query: 1264 PP 1265
P
Sbjct: 2700 TP 2701
Score = 102 bits (254), Expect = 3e-21
Identities = 125/542 (23%), Positives = 170/542 (31%), Gaps = 48/542 (8%)
Query: 768 PCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGS 827
P P G ++ T + ++ +P Q + P + + P P+ G P +
Sbjct: 2555 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---PTGTQTPTT 2611
Query: 828 QPPHSISTEFQT-----SHEHSVSSAFKNSCNIPSPPPL----PCTESSSSMPGLGMVPP 878
P + +T T + + + + P+P P P T ++ + P
Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2671
Query: 879 PPPPLPGMTVPTLPSTAI-----------PQPPPLQGTEMLPPPPPPLPGAGIPPPPPL- 926
P T P +T + P P+ T + P P P G P P+
Sbjct: 2672 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPIT 2730
Query: 927 PGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLP-GAGIPLPPPLPGAGIPPPPPLP-GA 984
+ P P G P P+ P P P G P P+ P P P G
Sbjct: 2731 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2790
Query: 985 GIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIP 1042
P P+ P P P G P P+ P P P G P P+
Sbjct: 2791 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2850
Query: 1043 PPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPP 1099
P P P G P P+ P P P G P P+ P P P G P
Sbjct: 2851 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2910
Query: 1100 PPLPGVGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPRVGIPPPPPL 1157
P+ P P P G P P+ P P P G P P+ P P
Sbjct: 2911 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2970
Query: 1158 P-GAGIPPPPPLPGAGIPPPPPLP-GVGIPPPPPLPGVGIPPPPPLP-GAGIPPPPPL-P 1213
P G P P+ P P P G P P+ P P P G P P+
Sbjct: 2971 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3030
Query: 1214 GMGIPPAPAP---------PLPPPGTGIPPPPLLPVSGPPLLPQVGSSTL-PTPQVCGFL 1263
+ P P P P+ T P P P P ++T+ PTP G
Sbjct: 3031 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3090
Query: 1264 PP 1265
P
Sbjct: 3091 TP 3092
Score = 102 bits (254), Expect = 3e-21
Identities = 125/542 (23%), Positives = 170/542 (31%), Gaps = 48/542 (8%)
Query: 768 PCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGS 827
P P G ++ T + ++ +P Q + P + + P P+ G P +
Sbjct: 2946 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---PTGTQTPTT 3002
Query: 828 QPPHSISTEFQT-----SHEHSVSSAFKNSCNIPSPPPL----PCTESSSSMPGLGMVPP 878
P + +T T + + + + P+P P P T ++ + P
Sbjct: 3003 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3062
Query: 879 PPPPLPGMTVPTLPSTAI-----------PQPPPLQGTEMLPPPPPPLPGAGIPPPPPL- 926
P T P +T + P P+ T + P P P G P P+
Sbjct: 3063 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPIT 3121
Query: 927 PGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLP-GAGIPLPPPLPGAGIPPPPPLP-GA 984
+ P P G P P+ P P P G P P+ P P P G
Sbjct: 3122 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3181
Query: 985 GIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIP 1042
P P+ P P P G P P+ P P P G P P+
Sbjct: 3182 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3241
Query: 1043 PPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPP 1099
P P P G P P+ P P P G P P+ P P P G P
Sbjct: 3242 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3301
Query: 1100 PPLPGVGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPRVGIPPPPPL 1157
P+ P P P G P P+ P P P G P P+ P P
Sbjct: 3302 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3361
Query: 1158 P-GAGIPPPPPLPGAGIPPPPPLP-GVGIPPPPPLPGVGIPPPPPLP-GAGIPPPPPL-P 1213
P G P P+ P P P G P P+ P P P G P P+
Sbjct: 3362 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3421
Query: 1214 GMGIPPAPAP---------PLPPPGTGIPPPPLLPVSGPPLLPQVGSSTL-PTPQVCGFL 1263
+ P P P P+ T P P P P ++T+ PTP G
Sbjct: 3422 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3481
Query: 1264 PP 1265
P
Sbjct: 3482 TP 3483
Score = 102 bits (254), Expect = 3e-21
Identities = 125/542 (23%), Positives = 170/542 (31%), Gaps = 48/542 (8%)
Query: 768 PCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGS 827
P P G ++ T + ++ +P Q + P + + P P+ G P +
Sbjct: 3337 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---PTGTQTPTT 3393
Query: 828 QPPHSISTEFQT-----SHEHSVSSAFKNSCNIPSPPPL----PCTESSSSMPGLGMVPP 878
P + +T T + + + + P+P P P T ++ + P
Sbjct: 3394 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3453
Query: 879 PPPPLPGMTVPTLPSTAI-----------PQPPPLQGTEMLPPPPPPLPGAGIPPPPPL- 926
P T P +T + P P+ T + P P P G P P+
Sbjct: 3454 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPIT 3512
Query: 927 PGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLP-GAGIPLPPPLPGAGIPPPPPLP-GA 984
+ P P G P P+ P P P G P P+ P P P G
Sbjct: 3513 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3572
Query: 985 GIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIP 1042
P P+ P P P G P P+ P P P G P P+
Sbjct: 3573 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3632
Query: 1043 PPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPP 1099
P P P G P P+ P P P G P P+ P P P G P
Sbjct: 3633 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3692
Query: 1100 PPLPGVGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPRVGIPPPPPL 1157
P+ P P P G P P+ P P P G P P+ P P
Sbjct: 3693 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3752
Query: 1158 P-GAGIPPPPPLPGAGIPPPPPLP-GVGIPPPPPLPGVGIPPPPPLP-GAGIPPPPPL-P 1213
P G P P+ P P P G P P+ P P P G P P+
Sbjct: 3753 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3812
Query: 1214 GMGIPPAPAP---------PLPPPGTGIPPPPLLPVSGPPLLPQVGSSTL-PTPQVCGFL 1263
+ P P P P+ T P P P P ++T+ PTP G
Sbjct: 3813 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3872
Query: 1264 PP 1265
P
Sbjct: 3873 TP 3874
Score = 101 bits (252), Expect = 5e-21
Identities = 109/419 (26%), Positives = 131/419 (31%), Gaps = 31/419 (7%)
Query: 877 PPPPPPLPGMTV------PTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPL-PGA 929
P PP P T PT T P P+ T + P P P G P P+
Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTT 1951
Query: 930 GILPLPPLPGAGIPPPPPLPGAAIPPPPPLP-GAGIPLPPPLPGAGIPPPPPLP-GAGIP 987
+ P P G P P+ P P P G P P+ P P P G P
Sbjct: 1952 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2011
Query: 988 PPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIPPPP 1045
P+ P P P G P P+ P P P G P P+ P
Sbjct: 2012 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2071
Query: 1046 PLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPL 1102
P P G P P+ P P P G P P+ P P P G P P+
Sbjct: 2072 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2131
Query: 1103 PGVGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPRVGIPPPPPLP-G 1159
P P P G P P+ P P P G P P+ P P P G
Sbjct: 2132 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2191
Query: 1160 AGIPPPPPLPGAGIPPPPPLP-GVGIPPPPPLPGVGIPPPPPLP-GAGIPPPPPL-PGMG 1216
P P+ P P P G P P+ P P P G P P+
Sbjct: 2192 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2251
Query: 1217 IPPAPAP---------PLPPPGTGIPPPPLLPVSGPPLLPQVGSSTL-PTPQVCGFLPP 1265
+ P P P P+ T P P P P ++T+ PTP G P
Sbjct: 2252 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2310
Score = 77.4 bits (189), Expect = 1e-13
Identities = 75/311 (24%), Positives = 97/311 (31%), Gaps = 21/311 (6%)
Query: 746 TSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQ 805
T+P+ T PP P P P T + + + P+
Sbjct: 1482 TTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSP 1541
Query: 806 SISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTE 865
+ P PP+ + S PP + +T T+ ++ + I + P P T
Sbjct: 1542 PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTT 1601
Query: 866 SSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPP 925
S PP P P T P P T+ PP P PPP P P
Sbjct: 1602 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPP----TTTPSPPPTTTTTPPPTTTP 1657
Query: 926 LPGAGILPLPPLPGAGIPPPPPLPGAAI--PPPPPLPGAGIPLPPPLPGAGIPPPPPLPG 983
P P PP+ PPP P + I P PP P P P + I
Sbjct: 1658 SPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSS 1717
Query: 984 AGIPPPPP----LPGAGIPPPPPLPGAGIPPP----PPLPGAGIPPPPPLPGAGIPPPPP 1035
P PPP P P PP PP PL +PP I PP
Sbjct: 1718 TTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPP-------SITPPTF 1770
Query: 1036 LPGAGIPPPPP 1046
P + P P
Sbjct: 1771 SPFSTTTPTTP 1781
Score = 40.0 bits (92), Expect = 0.020
Identities = 45/191 (23%), Positives = 66/191 (34%), Gaps = 18/191 (9%)
Query: 768 PCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGS 827
P P G ++ T + ++ +P Q + P + + P P+ + Q P +
Sbjct: 4142 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTGPPT 4199
Query: 828 QPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMT 887
+ E TS+ SS + S + SP T S+ P + M PP P T
Sbjct: 4200 HTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTP--T 4257
Query: 888 VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLP-----PLPGAGI 942
PT S G + PPP G P G+ P P A
Sbjct: 4258 APTTTS---------GGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWT 4308
Query: 943 PPPPPLPGAAI 953
P P PL +I
Sbjct: 4309 PTPTPLSTPSI 4319
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 148 bits (373), Expect = 5e-35
Identities = 110/298 (36%), Positives = 126/298 (42%), Gaps = 31/298 (10%)
Query: 866 SSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPP-PLQGTEMLPPPPPPLPGAGIPPPP 924
S SS P P P P PQP P Q + P A PPPP
Sbjct: 294 SQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPP 353
Query: 925 PLPGAGILPLPPLPGAGIPPP--PPLPGAA--IPPPPPLPGAGIP---LPPPLPGAGIPP 977
+P PPLP A PP PPL A PP P+ +P +PPP A +
Sbjct: 354 KIPKIETTH-PPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQ 412
Query: 978 PPPLPGAGIPPPPPLPGAGIPPPPP-LPGAGIPPPPPL-----PGAGIPPPPPLPGAGIP 1031
PPPLP PPPP G+ + G G + P G PP P A +P
Sbjct: 413 PPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLP 472
Query: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP- 1090
P + PPPPP+P PPP P IPPP P G PPPPP PPPPP
Sbjct: 473 YHPHVYPPN-PPPPPVP----PPPASFPPPAIPPPTP----GYPPPPPTYNPNFPPPPPR 523
Query: 1091 LPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPR 1148
LP PP P PG+G+PP A PPP PG P PPP+P G+PP L R
Sbjct: 524 LPPTHAVPPHPPPGLGLPP------ASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLGR 575
Score = 147 bits (371), Expect = 9e-35
Identities = 114/317 (35%), Positives = 132/317 (41%), Gaps = 35/317 (11%)
Query: 896 IPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPP-PLPGAAIP 954
+ QPP LQ T +P P P P P A P P P P +
Sbjct: 273 LQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSS--- 329
Query: 955 PPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP--PPLPGA--GIPP 1010
P + A + P A PPPP +P PP LP A PP PPL A P
Sbjct: 330 -PRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPP-LPPAHPPPDRKPPLAAALGEAEP 387
Query: 1011 PPPLPGAGIPP---PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP-LPGAGIPPP 1066
P P+ +P PPP A + PPPLP PPPP G+ + G G
Sbjct: 388 PGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSL 447
Query: 1067 PPL-----PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPP 1121
+ P G PP P A +P P + PPPPP+P PPP P IPPP
Sbjct: 448 QSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPN-PPPPPVP----PPPASFPPPAIPPP 502
Query: 1122 PPLPGAGIPPPPPLPGAGIPPPPP-LPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1180
P G PPPPP PPPPP LP PP P PG G+PP A PPP P
Sbjct: 503 TP----GYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPP------ASYPPPAVPP 552
Query: 1181 GVGIPPPPPLPGVGIPP 1197
G P PPP+P G+PP
Sbjct: 553 GGQPPVPPPIPPPGMPP 569
Score = 138 bits (347), Expect = 5e-32
Identities = 110/314 (35%), Positives = 131/314 (41%), Gaps = 35/314 (11%)
Query: 952 AIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1011
++ P P +P P + P P P P P P P + P
Sbjct: 278 SLQPTPQVPQVQQSQPSQ---SSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSS----P 330
Query: 1012 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP--PPLPGA--GIPPPP 1067
+ A + P A PPPP +P PP LP A PP PPL A PP
Sbjct: 331 RQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPP-LPPAHPPPDRKPPLAAALGEAEPPG 389
Query: 1068 PLPGAGIPP---PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP-LPGAGIPPPPP 1123
P+ +P PPP A + PPPLP PPPP G+ + G G
Sbjct: 390 PVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQS 449
Query: 1124 L-----PGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1178
+ P G PP P A +P P + PPPPP+P PPP P IPPP P
Sbjct: 450 MMKTEGPSYGALPPAYGPPAHLPYHPHVYPPN-PPPPPVP----PPPASFPPPAIPPPTP 504
Query: 1179 LPGVGIPPPPPLPGVGIPPPPP-LPGAGIPPPPPLPGMGIPPAP-APPLPPPGTGIPPPP 1236
G PPPPP PPPPP LP PP P PG+G+PPA PP PPG P PP
Sbjct: 505 ----GYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPP 560
Query: 1237 LLPVSGPPLLPQVG 1250
+P PP +P VG
Sbjct: 561 PIP---PPGMPPVG 571
Score = 129 bits (323), Expect = 3e-29
Identities = 105/306 (34%), Positives = 126/306 (41%), Gaps = 71/306 (23%)
Query: 797 QLDSHQPTQSISQPPPPPSL--LWSAGQGQPGSQPPHSI---STEFQTSHEHSVSSAFKN 851
Q+ QP+QS S+P P A Q QP QP S+ Q VS +N
Sbjct: 287 QVQQSQPSQS-SEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEEN 345
Query: 852 SCNIPSPPPLPCTESSSSMPGLGMVPPPPP--PLPGMTVPTLPSTAIPQPP-PLQGTEM- 907
P PP +P E++ PP PP P P P + +PP P+ T++
Sbjct: 346 KAAEPPPPKIPKIETTH--------PPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLP 397
Query: 908 ---LPPP--------PPPLPGAGIPPPPP------------LPGAGILPLPPL-----PG 939
+PPP PPPLP PPPP + G G L + P
Sbjct: 398 KVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPS 457
Query: 940 AGIPPPPPLPGAAIP----------PPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPP 989
G PP P A +P PPPP+P PPP IPPP P G PPP
Sbjct: 458 YGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPP----AIPPPTP----GYPPP 509
Query: 990 PPLPGAGIPPPPP-LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1048
PP PPPPP LP PP P PG G+PP A PPP PG P PPP+P
Sbjct: 510 PPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPP------ASYPPPAVPPGGQPPVPPPIP 563
Query: 1049 GAGIPP 1054
G+PP
Sbjct: 564 PPGMPP 569
Score = 99.8 bits (247), Expect = 2e-20
Identities = 90/295 (30%), Positives = 113/295 (38%), Gaps = 75/295 (25%)
Query: 742 KSIQTSPTEEGGVLTLPPVDGLPG----RPPCPPGAESGPQTK--FCSEISLIVSPRRIS 795
+++ SP EE PP +P PP PP A P K + + P +
Sbjct: 335 RAVVVSPKEENKAAE-PPPPKIPKIETTHPPLPP-AHPPPDRKPPLAAALGEAEPPGPVD 392
Query: 796 ------VQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAF 849
VQ+ + QPPP P +P PP S T T+ + +
Sbjct: 393 ATDLPKVQIPPPAHPAPVHQPPPLPH--------RPPPPPPSSYMTGMSTTSSYMSGEGY 444
Query: 850 KNSCNIPSPPPLPCTESSSSMPGLGMVPP---PPPPLPGMTVPTLPSTAIPQPPPLQGTE 906
++ ++ TE P G +PP PP LP P P PPP
Sbjct: 445 QSLQSMMK------TEG----PSYGALPPAYGPPAHLPYH-----PHVYPPNPPP----P 485
Query: 907 MLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPL 966
+PPPP P IPPP P G PPPPP PPPPP L
Sbjct: 486 PVPPPPASFPPPAIPPPTP---------------GYPPPPPTYNPNFPPPPP------RL 524
Query: 967 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1021
PP +PP PP PG G+PP A PPP PG P PPP+P G+PP
Sbjct: 525 PPT---HAVPPHPP-PGLGLPP------ASYPPPAVPPGGQPPVPPPIPPPGMPP 569
Score = 73.2 bits (178), Expect = 2e-12
Identities = 56/173 (32%), Positives = 76/173 (43%), Gaps = 27/173 (15%)
Query: 801 HQPTQSISQPPPPPSLLWSAGQGQPGS----QPPHSISTEFQTSHEH--SVSSAFKNSCN 854
HQP +PPPPP + G S + S+ + +T ++ A+ +
Sbjct: 411 HQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAH 470
Query: 855 IP--------SPPPLPCTESSSSMPGLGMVPPPP--PPLPGMTVPTLPSTAIPQPPPLQG 904
+P +PPP P +S P + PP P PP P P P P PP L
Sbjct: 471 LPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFP----PPPPRLPP 526
Query: 905 TEMLPPPPPPLPGAGIPP----PPPLPGAGILPLPP-LPGAGIPPPPPLPGAA 952
T +PP PPP G G+PP PP +P G P+PP +P G+PP L AA
Sbjct: 527 THAVPPHPPP--GLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLGRAA 577
Score = 36.6 bits (83), Expect = 0.22
Identities = 41/151 (27%), Positives = 58/151 (38%), Gaps = 14/151 (9%)
Query: 191 EQEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQ-QQLQGAEEPAAPPTAVSPQPGAFLGL 249
+Q L Q ++QQ Q Q Q QQ+ QQ ++PA P SPQP + +
Sbjct: 274 QQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQV 333
Query: 250 DRFLLGPSGGAGEA--PGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAP-- 305
R ++ +A P P + + LP A P ++PP L +E P
Sbjct: 334 KRAVVVSPKEENKAAEPPPPKIPKIETTHPPLP---PAHPPPDRKPPLAAALGEAEPPGP 390
Query: 306 ----SLPAAQ--PAAKDSPSSTAFPFPEAGP 330
LP Q P A +P P P P
Sbjct: 391 VDATDLPKVQIPPPAHPAPVHQPPPLPHRPP 421
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.135 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 115,914,996
Number of Sequences: 37866
Number of extensions: 11779377
Number of successful extensions: 368625
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1192
Number of HSP's successfully gapped in prelim test: 2221
Number of HSP's that attempted gapping in prelim test: 70159
Number of HSP's gapped (non-prelim): 90952
length of query: 1722
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1606
effective length of database: 13,855,062
effective search space: 22251229572
effective search space used: 22251229572
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.