Guide to the Human Genome
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Search of human proteins with 157817101

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157817101 HIG1 domain family, member 1C [Homo sapiens]
         (97 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157817101 HIG1 domain family, member 1C [Homo sapiens]             196   3e-51
gi|153085470 HIG1 domain family, member 1A isoform b [Homo sapiens]   108   9e-25
gi|153085461 HIG1 domain family, member 1A isoform a [Homo sapiens]   108   9e-25
gi|153085463 HIG1 domain family, member 1A isoform b [Homo sapiens]   108   9e-25
gi|239755597 PREDICTED: similar to HIG1 domain family, member 1A...   104   2e-23
gi|239750094 PREDICTED: similar to HIG1 domain family, member 1A...   104   2e-23
gi|239744403 PREDICTED: hypothetical protein XP_002343136 [Homo ...   104   2e-23
gi|7706543 HIG1 hypoxia inducible domain family, member 1B [Homo...    90   3e-19
gi|20270389 HIG1 hypoxia inducible domain family, member 2A [Hom...    49   1e-06
gi|169202111 PREDICTED: similar to HIG1 domain family, member 2A...    28   1.6  
gi|30578410 source of immunodominant MHC-associated peptides [Ho...    27   3.5  
gi|61744473 melanoma antigen family A, 11 isoform b [Homo sapiens]     26   7.8  
gi|65507078 melanoma antigen family A, 11 isoform a [Homo sapiens]     26   7.8  

>gi|157817101 HIG1 domain family, member 1C [Homo sapiens]
          Length = 97

 Score =  196 bits (498), Expect = 3e-51
 Identities = 97/97 (100%), Positives = 97/97 (100%)

Query: 1  MSSDNQWSADEDEGQLSRLIRKSRDSPFVPIGIAGFVTVVSCGLYKLKYRRDQKMSIHLI 60
          MSSDNQWSADEDEGQLSRLIRKSRDSPFVPIGIAGFVTVVSCGLYKLKYRRDQKMSIHLI
Sbjct: 1  MSSDNQWSADEDEGQLSRLIRKSRDSPFVPIGIAGFVTVVSCGLYKLKYRRDQKMSIHLI 60

Query: 61 HMRVAAQGFVVGAVTLGVLYSMYKDYIRPRFFSESKK 97
          HMRVAAQGFVVGAVTLGVLYSMYKDYIRPRFFSESKK
Sbjct: 61 HMRVAAQGFVVGAVTLGVLYSMYKDYIRPRFFSESKK 97


>gi|153085470 HIG1 domain family, member 1A isoform b [Homo
          sapiens]
          Length = 93

 Score =  108 bits (270), Expect = 9e-25
 Identities = 52/79 (65%), Positives = 69/79 (87%), Gaps = 2/79 (2%)

Query: 8  SADEDEGQLSRLIRKSRDSPFVPIGIAGFVTVVSCGLYKLKYRRDQKMSIHLIHMRVAAQ 67
          S +ED+G  S+LIRK++++PFVP+GIAGF  +V+ GLYKLK R + KMSIHLIHMRVAAQ
Sbjct: 11 SYEEDQG--SKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHLIHMRVAAQ 68

Query: 68 GFVVGAVTLGVLYSMYKDY 86
          GFVVGA+T+G+ YSMY+++
Sbjct: 69 GFVVGAMTVGMGYSMYREF 87


>gi|153085461 HIG1 domain family, member 1A isoform a [Homo sapiens]
          Length = 107

 Score =  108 bits (270), Expect = 9e-25
 Identities = 52/79 (65%), Positives = 69/79 (87%), Gaps = 2/79 (2%)

Query: 8   SADEDEGQLSRLIRKSRDSPFVPIGIAGFVTVVSCGLYKLKYRRDQKMSIHLIHMRVAAQ 67
           S +ED+G  S+LIRK++++PFVP+GIAGF  +V+ GLYKLK R + KMSIHLIHMRVAAQ
Sbjct: 25  SYEEDQG--SKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHLIHMRVAAQ 82

Query: 68  GFVVGAVTLGVLYSMYKDY 86
           GFVVGA+T+G+ YSMY+++
Sbjct: 83  GFVVGAMTVGMGYSMYREF 101


>gi|153085463 HIG1 domain family, member 1A isoform b [Homo
          sapiens]
          Length = 93

 Score =  108 bits (270), Expect = 9e-25
 Identities = 52/79 (65%), Positives = 69/79 (87%), Gaps = 2/79 (2%)

Query: 8  SADEDEGQLSRLIRKSRDSPFVPIGIAGFVTVVSCGLYKLKYRRDQKMSIHLIHMRVAAQ 67
          S +ED+G  S+LIRK++++PFVP+GIAGF  +V+ GLYKLK R + KMSIHLIHMRVAAQ
Sbjct: 11 SYEEDQG--SKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHLIHMRVAAQ 68

Query: 68 GFVVGAVTLGVLYSMYKDY 86
          GFVVGA+T+G+ YSMY+++
Sbjct: 69 GFVVGAMTVGMGYSMYREF 87


>gi|239755597 PREDICTED: similar to HIG1 domain family, member 1A
           [Homo sapiens]
          Length = 124

 Score =  104 bits (259), Expect = 2e-23
 Identities = 48/75 (64%), Positives = 65/75 (86%)

Query: 12  DEGQLSRLIRKSRDSPFVPIGIAGFVTVVSCGLYKLKYRRDQKMSIHLIHMRVAAQGFVV 71
           DE Q S+LIRK++++P VP+GIAGF  +V+ GLYKLK R + +MS+HLIHMRVAAQGFVV
Sbjct: 44  DEAQGSKLIRKAKETPLVPVGIAGFAALVTYGLYKLKSRGNTQMSLHLIHMRVAAQGFVV 103

Query: 72  GAVTLGVLYSMYKDY 86
           GA+T+G+ YSMY+++
Sbjct: 104 GAMTIGMGYSMYREF 118


>gi|239750094 PREDICTED: similar to HIG1 domain family, member 1A
           [Homo sapiens]
          Length = 124

 Score =  104 bits (259), Expect = 2e-23
 Identities = 48/75 (64%), Positives = 65/75 (86%)

Query: 12  DEGQLSRLIRKSRDSPFVPIGIAGFVTVVSCGLYKLKYRRDQKMSIHLIHMRVAAQGFVV 71
           DE Q S+LIRK++++P VP+GIAGF  +V+ GLYKLK R + +MS+HLIHMRVAAQGFVV
Sbjct: 44  DEAQGSKLIRKAKETPLVPVGIAGFAALVTYGLYKLKSRGNTQMSLHLIHMRVAAQGFVV 103

Query: 72  GAVTLGVLYSMYKDY 86
           GA+T+G+ YSMY+++
Sbjct: 104 GAMTIGMGYSMYREF 118


>gi|239744403 PREDICTED: hypothetical protein XP_002343136 [Homo
           sapiens]
          Length = 124

 Score =  104 bits (259), Expect = 2e-23
 Identities = 48/75 (64%), Positives = 65/75 (86%)

Query: 12  DEGQLSRLIRKSRDSPFVPIGIAGFVTVVSCGLYKLKYRRDQKMSIHLIHMRVAAQGFVV 71
           DE Q S+LIRK++++P VP+GIAGF  +V+ GLYKLK R + +MS+HLIHMRVAAQGFVV
Sbjct: 44  DEAQGSKLIRKAKETPLVPVGIAGFAALVTYGLYKLKSRGNTQMSLHLIHMRVAAQGFVV 103

Query: 72  GAVTLGVLYSMYKDY 86
           GA+T+G+ YSMY+++
Sbjct: 104 GAMTIGMGYSMYREF 118


>gi|7706543 HIG1 hypoxia inducible domain family, member 1B [Homo
          sapiens]
          Length = 99

 Score = 90.1 bits (222), Expect = 3e-19
 Identities = 42/90 (46%), Positives = 63/90 (70%), Gaps = 2/90 (2%)

Query: 1  MSSDNQW--SADEDEGQLSRLIRKSRDSPFVPIGIAGFVTVVSCGLYKLKYRRDQKMSIH 58
          MS++ +W    D+++    +L+RK+R+SP VPIG+ G + V +  +Y+L+ R   KMSIH
Sbjct: 1  MSANRRWWVPPDDEDCVSEKLLRKTRESPLVPIGLGGCLVVAAYRIYRLRSRGSTKMSIH 60

Query: 59 LIHMRVAAQGFVVGAVTLGVLYSMYKDYIR 88
          LIH RVAAQ   VGA+ LG +Y+MY DY++
Sbjct: 61 LIHTRVAAQACAVGAIMLGAVYTMYSDYVK 90


>gi|20270389 HIG1 hypoxia inducible domain family, member 2A [Homo
           sapiens]
          Length = 106

 Score = 48.5 bits (114), Expect = 1e-06
 Identities = 24/67 (35%), Positives = 40/67 (59%), Gaps = 1/67 (1%)

Query: 18  RLIRKSRDSPFVPIGIAGFVTVVSCGLYKLKYRRDQKMSIHLIHMRVAAQGFVVGAVTLG 77
           + +RK+R++P VPIG       ++ GLY   +R + + S  ++  R+AAQGF V A+ LG
Sbjct: 38  KFVRKTRENPVVPIGCLATAAALTYGLYSF-HRGNSQRSQLMMRTRIAAQGFTVAAILLG 96

Query: 78  VLYSMYK 84
           +  +  K
Sbjct: 97  LAVTAMK 103


>gi|169202111 PREDICTED: similar to HIG1 domain family, member 2A
           [Homo sapiens]
          Length = 103

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 16/61 (26%), Positives = 29/61 (47%)

Query: 22  KSRDSPFVPIGIAGFVTVVSCGLYKLKYRRDQKMSIHLIHMRVAAQGFVVGAVTLGVLYS 81
           K+  +P VPIG       ++  L+   Y+   +    +    +  QGF V A+ L +L+S
Sbjct: 41  KTCKNPTVPIGCLSKAITLTYSLFYCFYQGHSQCFQLMTRTCITTQGFTVTAILLHLLWS 100

Query: 82  M 82
           +
Sbjct: 101 L 101


>gi|30578410 source of immunodominant MHC-associated peptides [Homo
           sapiens]
          Length = 826

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 17/50 (34%), Positives = 22/50 (44%), Gaps = 3/50 (6%)

Query: 47  LKYRRDQKMSIHLIHMRVAAQGFVVGAVTLGVLYSMYKDYIRP---RFFS 93
           L+Y RD+        +         GAV L V+Y  Y  YI P   RF+S
Sbjct: 337 LQYLRDRLTKQEFQTLFFLGVSLAAGAVFLSVIYLTYTGYIAPWSGRFYS 386


>gi|61744473 melanoma antigen family A, 11 isoform b [Homo sapiens]
          Length = 400

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 12/39 (30%), Positives = 20/39 (51%), Gaps = 1/39 (2%)

Query: 57  IHLIHMRVAAQGFVVGAVTLGVLYSMYKDYIRPRFFSES 95
           +HL+  +   +G +  A  LG +   Y+DY  P  F E+
Sbjct: 201 VHLLLRKYRVKGLITKAEMLGSVIKNYEDYF-PEIFREA 238


>gi|65507078 melanoma antigen family A, 11 isoform a [Homo sapiens]
          Length = 429

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 12/39 (30%), Positives = 20/39 (51%), Gaps = 1/39 (2%)

Query: 57  IHLIHMRVAAQGFVVGAVTLGVLYSMYKDYIRPRFFSES 95
           +HL+  +   +G +  A  LG +   Y+DY  P  F E+
Sbjct: 230 VHLLLRKYRVKGLITKAEMLGSVIKNYEDYF-PEIFREA 267


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.137    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,233,794
Number of Sequences: 37866
Number of extensions: 103948
Number of successful extensions: 262
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 250
Number of HSP's gapped (non-prelim): 14
length of query: 97
length of database: 18,247,518
effective HSP length: 68
effective length of query: 29
effective length of database: 15,672,630
effective search space: 454506270
effective search space used: 454506270
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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