Search of human proteins with 157671931

Search of human proteins with 157671931

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157671931 solute carrier family 5 (sodium/glucose
cotransporter), member 12 [Homo sapiens]
         (618 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157671931 solute carrier family 5 (sodium/glucose cotransport...  1259   0.0  
gi|167466278 solute carrier family 5 (iodide transporter), membe...   648   0.0  
gi|4507035 solute carrier family 5 (sodium iodide symporter), me...   537   e-152
gi|10863879 solute carrier family 5 (sodium-dependent vitamin tr...   481   e-136
gi|17941285 solute carrier family 5 (sodium/glucose cotransporte...   141   2e-33
gi|14140236 solute carrier family 5 (low affinity glucose cotran...   132   7e-31
gi|4507031 solute carrier family 5 (sodium/glucose cotransporter...   122   7e-28
gi|109659836 solute carrier family 5 (sodium/glucose cotransport...   122   1e-27
gi|109659839 solute carrier family 5 (sodium/glucose cotransport...   119   1e-26
gi|206597483 solute carrier family 5 (sodium/glucose cotransport...   112   8e-25
gi|110835708 solute carrier family 5 (inositol transporters), me...   111   2e-24
gi|4507033 solute carrier family 5 (sodium/glucose cotransporter...   107   4e-23
gi|206597487 solute carrier family 5 (sodium/glucose cotransport...   100   7e-21
gi|11141885 solute carrier family 5 (choline transporter), membe...    70   4e-12
gi|27734719 solute carrier family 19, member 2 [Homo sapiens]          32   2.3  
gi|239582720 ATG9 autophagy related 9 homolog B [Homo sapiens]         31   3.0  
gi|6005715 solute carrier family 6 (amino acid transporter), mem...    31   3.0  
gi|31543630 solute carrier family 20 (phosphate transporter), me...    31   3.0  
gi|14249528 solute carrier family 35, member B4 [Homo sapiens]         30   6.6  
gi|53828710 olfactory receptor, family 5, subfamily D, member 16...    30   6.6  

>gi|157671931 solute carrier family 5 (sodium/glucose
           cotransporter), member 12 [Homo sapiens]
          Length = 618

 Score = 1259 bits (3257), Expect = 0.0
 Identities = 618/618 (100%), Positives = 618/618 (100%)

Query: 1   MEVKNFAVWDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTAS 60
           MEVKNFAVWDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTAS
Sbjct: 1   MEVKNFAVWDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTAS 60

Query: 61  FMSAVTVLGTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFN 120
           FMSAVTVLGTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFN
Sbjct: 61  FMSAVTVLGTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFN 120

Query: 121 KPVRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKA 180
           KPVRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKA
Sbjct: 121 KPVRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKA 180

Query: 181 VVWTDAFQMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRHTFWT 240
           VVWTDAFQMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRHTFWT
Sbjct: 181 VVWTDAFQMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRHTFWT 240

Query: 241 ITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCAVFSGLIMYSH 300
           ITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCAVFSGLIMYSH
Sbjct: 241 ITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCAVFSGLIMYSH 300

Query: 301 FKDCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASSINALATVT 360
           FKDCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASSINALATVT
Sbjct: 301 FKDCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASSINALATVT 360

Query: 361 FEDFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSMAVAASVMGGVVQASLSIHGMCGGPM 420
           FEDFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSMAVAASVMGGVVQASLSIHGMCGGPM
Sbjct: 361 FEDFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSMAVAASVMGGVVQASLSIHGMCGGPM 420

Query: 421 LGLFSLGIVFPFVNWKGALGGLLTGITLSFWVAIGAFIYPAPASKTWPLPLSTDQCIKSN 480
           LGLFSLGIVFPFVNWKGALGGLLTGITLSFWVAIGAFIYPAPASKTWPLPLSTDQCIKSN
Sbjct: 421 LGLFSLGIVFPFVNWKGALGGLLTGITLSFWVAIGAFIYPAPASKTWPLPLSTDQCIKSN 480

Query: 481 VTATGPPVLSSRPGIADTWYSISYLYYSAVGCLGCIVAGVIISLITGRQRGEDIQPLLIR 540
           VTATGPPVLSSRPGIADTWYSISYLYYSAVGCLGCIVAGVIISLITGRQRGEDIQPLLIR
Sbjct: 481 VTATGPPVLSSRPGIADTWYSISYLYYSAVGCLGCIVAGVIISLITGRQRGEDIQPLLIR 540

Query: 541 PVCNLFCFWSKKYKTLCWCGVQHDSGTEQENLENGSARKQGAESVLQNGLRRESLVHVPG 600
           PVCNLFCFWSKKYKTLCWCGVQHDSGTEQENLENGSARKQGAESVLQNGLRRESLVHVPG
Sbjct: 541 PVCNLFCFWSKKYKTLCWCGVQHDSGTEQENLENGSARKQGAESVLQNGLRRESLVHVPG 600

Query: 601 YDPKDKSYNNMAFETTHF 618
           YDPKDKSYNNMAFETTHF
Sbjct: 601 YDPKDKSYNNMAFETTHF 618


>gi|167466278 solute carrier family 5 (iodide transporter), member 8
           [Homo sapiens]
          Length = 610

 Score =  648 bits (1671), Expect = 0.0
 Identities = 321/582 (55%), Positives = 418/582 (71%), Gaps = 16/582 (2%)

Query: 3   VKNFAVWDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFM 62
           +  F VWDYVVFA +  IS+ IG+++A     + TS++FL+GGR+M+  PV LSLTASFM
Sbjct: 7   IGTFVVWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFM 66

Query: 63  SAVTVLGTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFNKP 122
           SAVTVLGTPSEVYRFGA F +F   Y FV+++++E+FLPVFY+ GITSTYEYL+LRFNK 
Sbjct: 67  SAVTVLGTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRFNKC 126

Query: 123 VRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVV 182
           VR   TV++IVQTILYTG+V+YAPALALNQVTGFDLWG+V ATG+VCTFYCTLGGLKAV+
Sbjct: 127 VRLCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVI 186

Query: 183 WTDAFQMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRHTFWTIT 242
           WTD FQ+ +M+ GF +V+IQ     GG   +L  + +G RL+ ++F+ +PL+RHTFWTI 
Sbjct: 187 WTDVFQVGIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQRHTFWTII 246

Query: 243 VGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCAVFSGLIMYSHFK 302
           +GGTFTW  IYGVNQS +QR ISCK+   AKL+LY NL+GLW IL C+VF GL +YS + 
Sbjct: 247 IGGTFTWTSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGLALYSRYH 306

Query: 303 DCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASSINALATVTFE 362
           DCDPWT+  +SAPDQLMPY V++I    PGLPGLFVACA+SGTLSTV+SSINALA VT E
Sbjct: 307 DCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINALAAVTVE 366

Query: 363 DFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSMAVAASVMGGVVQASLSIHGMCGGPMLG 422
           D +K  F  LS++  +WIS+G+ +++G +C  MA  AS+MG ++QA+LS+ GM GGP++G
Sbjct: 367 DLIKPYFRSLSERSLSWISQGMSVVYGALCIGMAALASLMGALLQAALSVFGMVGGPLMG 426

Query: 423 LFSLGIVFPFVNWKGALGGLLTGITLSFWVAIGAFIYPAPASKTWPLPLSTDQCIKSN-- 480
           LF+LGI+ PF N  GAL GL+ G  +S WV IGA IYP    +T PL L    C  +   
Sbjct: 427 LFALGILVPFANSIGALVGLMAGFAISLWVGIGAQIYPPLPERTLPLHLDIQGCNSTYNE 486

Query: 481 ---VTATGPPVLSS--------RPGIADTWYSISYLYYSAVGCLGCIVAGVIISLIT-GR 528
              +T T  P  +S        R  + D WYS+SYLY+S VG L  ++ G+++SL T GR
Sbjct: 487 TNLMTTTEMPFTTSVFQIYNVQRTPLMDNWYSLSYLYFSTVGTLVTLLVGILVSLSTGGR 546

Query: 529 QRGEDIQPLLIRP--VCNLFCFWSKKYKTLCWCGVQHDSGTE 568
           ++  D + +L +   + N   F  KK+          D GT+
Sbjct: 547 KQNLDPRYILTKEDFLSNFDIFKKKKHVLSYKSHPVEDGGTD 588


>gi|4507035 solute carrier family 5 (sodium iodide symporter),
           member 5 [Homo sapiens]
          Length = 643

 Score =  537 bits (1383), Expect = e-152
 Identities = 269/556 (48%), Positives = 372/556 (66%), Gaps = 18/556 (3%)

Query: 2   EVKNFAVWDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASF 61
           E   F  WDY VFA +  +S+GIG++  +    + ++ +F  GGR+++  PVGLSL+ASF
Sbjct: 8   ERPTFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASF 67

Query: 62  MSAVTVLGTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFNK 121
           MSAV VLG PSE YR+G  FL   +  L   +LT+ LF+PVFYR G+TSTYEYL++RF++
Sbjct: 68  MSAVQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFSR 127

Query: 122 PVRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAV 181
            VR   T+ YIV T+LYTG+V+YAPAL LNQVTG D+W S+ +TGI+CTFY  +GG+KAV
Sbjct: 128 AVRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAV 187

Query: 182 VWTDAFQMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRHTFWTI 241
           VWTD FQ+VVM+ GF  VL +G    GG   VL  + N SR+++ DF+ DP  R+TFWT 
Sbjct: 188 VWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTF 247

Query: 242 TVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCAVFSGLIMYSHF 301
            VGGT  WL +YGVNQ+ +QR ++C+TEK AKLAL  N +GL++I+  A   G++M+  +
Sbjct: 248 VVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFVFY 307

Query: 302 KDCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASSINALATVTF 361
            DCDP   G ISAPDQ MP  V++IF  +PG+PGLF+ACA+SGTLST ++SINA+A VT 
Sbjct: 308 TDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTV 367

Query: 362 EDFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSMAVAASVM-GGVVQASLSIHGMCGGPM 420
           ED +K     L+ +    ISKGL L++G  C ++A  +S++ GGV+Q S ++ G+  GP+
Sbjct: 368 EDLIKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPL 427

Query: 421 LGLFSLGIVFPFVNWKGALGGLLTGITLSFWVAIGAFIYPAPASKTWPLPLSTDQCIKSN 480
           LG F LG+  P  N  G L GL  G+ LS WVA+GA +YP        LP S  +C+  +
Sbjct: 428 LGAFILGMFLPACNTPGVLAGLGAGLALSLWVALGATLYPPSEQTMRVLPSSAARCVALS 487

Query: 481 VTATG---PPVL--------------SSRPGIADTWYSISYLYYSAVGCLGCIVAGVIIS 523
           V A+G   P +L              +SRP +AD++Y+ISYLYY A+G L  ++ G +IS
Sbjct: 488 VNASGLLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTVLCGALIS 547

Query: 524 LITGRQRGEDIQPLLI 539
            +TG  +   + P L+
Sbjct: 548 CLTGPTKRSTLAPGLL 563


>gi|10863879 solute carrier family 5 (sodium-dependent vitamin
           transporter), member 6 [Homo sapiens]
          Length = 635

 Score =  481 bits (1238), Expect = e-136
 Identities = 250/546 (45%), Positives = 342/546 (62%), Gaps = 7/546 (1%)

Query: 3   VKNFAVWDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFM 62
           +  F++ DYVVF  L  +S  IG++ A +   + T  E L+  R+M   PV LSL A+F 
Sbjct: 21  MSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQ 80

Query: 63  SAVTVLGTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFNKP 122
           SAV +LG PSE+YRFG  +      Y   +L+ + +F+PVFYR  +TS YEYL+LRFNK 
Sbjct: 81  SAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFNKT 140

Query: 123 VRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVV 182
           VR   TV +I Q ++Y GVV+YAP+LALN VTGFDLW SV A GIVCT Y  LGGLKAV+
Sbjct: 141 VRVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVI 200

Query: 183 WTDAFQMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRHTFWTIT 242
           WTD FQ +VM +G L V+I GS   GG   V   ++   R+  F+ D DP  RHTFWT+ 
Sbjct: 201 WTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVRHTFWTLA 260

Query: 243 VGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCAVFSGLIMYSHFK 302
            GG F  L +YGVNQ+ +QR +S +TEK A L+ Y       + L      GL+M+++++
Sbjct: 261 FGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCLIGLVMFAYYQ 320

Query: 303 DCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASSINALATVTFE 362
           +         +APDQ + YFVM++   +PGLPGLF+AC FSG+LST++S+ N+LATVT E
Sbjct: 321 EYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNSLATVTME 380

Query: 363 DFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSMAVAASVMGGVVQASLSIHGMCGGPMLG 422
           D ++  FP  S+  +  +S+GL   +G++C  MA  +S MG V+QA++SI GM GGP+LG
Sbjct: 381 DLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYISSQMGPVLQAAISIFGMVGGPLLG 440

Query: 423 LFSLGIVFPFVNWKGALGGLLTGITLSFWVAIGA------FIYPAPASKTWPLPLSTDQC 476
           LF LG+ FP  N  GA+ GLL G+ ++FW+ IG+      F  P   S      L T+  
Sbjct: 441 LFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIGSIVTSMGFSMPPSPSNGSSFSLPTNLT 500

Query: 477 IKSNVTATGPPVLSSRPGIADTWYSISYLYYSAVGCLGCIVAGVIISLITGRQRGEDIQP 536
           + + VT   P    S+P     +YS+SYL+YSA      IV G+I+SL+TGR RG  + P
Sbjct: 501 V-ATVTTLMPLTTFSKPTGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLTGRMRGRSLNP 559

Query: 537 LLIRPV 542
             I PV
Sbjct: 560 ATIYPV 565


>gi|17941285 solute carrier family 5 (sodium/glucose cotransporter),
           member 11 [Homo sapiens]
          Length = 675

 Score =  141 bits (355), Expect = 2e-33
 Identities = 131/487 (26%), Positives = 211/487 (43%), Gaps = 44/487 (9%)

Query: 10  DYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFMSAVTVLG 69
           D  V    F     +G++  +K ++      FL GG  M + PVG SL AS + +   +G
Sbjct: 28  DIAVLVLYFLFVLAVGLWSTVKTKRDTVKGYFLAGG-DMVWWPVGASLFASNVGSGHFIG 86

Query: 70  TPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFNK---PVRYA 126
                   G S   + +  LF +L+ + +FLP++    +T+  EYL+ RF     P+  A
Sbjct: 87  LAGSGAATGISVSAYELNGLFSVLMLAWIFLPIYIAGQVTTMPEYLRKRFGGIRIPIILA 146

Query: 127 ATVIYIVQTILYTGVVV--YAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWT 184
              ++I    ++T + V  YA A+ + Q    DL+ ++     +   Y   GGL AV++T
Sbjct: 147 VLYLFIY---IFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITAVYTVAGGLAAVIYT 203

Query: 185 DAFQMVVMIVGFLTVLIQGSTHAGGFHNVLE---------QSTNGS----RLHIFDFDVD 231
           DA Q ++M++G LT++       GG   + E         +S N S    R   F    D
Sbjct: 204 DALQTLIMLIGALTLMGYSFAAVGGMEGLKEKYFLALASNRSENSSCGLPREDAFHIFRD 263

Query: 232 PLRRHTFWT-ITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAK----LALYFNLLGLWII 286
           PL     W  +  G +   L  +  +Q  +QR ++ K   HAK    +A Y  +L L+I+
Sbjct: 264 PLTSDLPWPGVLFGMSIPSLWYWCTDQVIVQRTLAAKNLSHAKGGALMAAYLKVLPLFIM 323

Query: 287 LVCAVFSGLIMYSHFKD---------CDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLF 337
               VF G++    F D         C    S      D   P  V+E+  T  GL GL 
Sbjct: 324 ----VFPGMVSRILFPDQVACADPEICQKICSNPSGCSDIAYPKLVLELLPT--GLRGLM 377

Query: 338 VACAFSGTLSTVASSINALATVTFEDFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSM-- 395
           +A   +  +S++ S  N+ +T+   D      P  S+K    + +   LL  ++      
Sbjct: 378 MAVMVAALMSSLTSIFNSASTIFTMDLWNHLRPRASEKELMIVGRVFVLLLVLVSILWIP 437

Query: 396 AVAASVMGGVVQASLSIHGMCGGPMLGLFSLGIVFPFVNWKGALGGLLTGITLSFWVAIG 455
            V AS  G +     SI      P+  +F +G  +   N KGA  GL++G+ L     + 
Sbjct: 438 VVQASQGGQLFIYIQSISSYLQPPVAVVFIMGCFWKRTNEKGAFWGLISGLLLGLVRLVL 497

Query: 456 AFIYPAP 462
            FIY  P
Sbjct: 498 DFIYVQP 504


>gi|14140236 solute carrier family 5 (low affinity glucose
           cotransporter), member 4 [Homo sapiens]
          Length = 659

 Score =  132 bits (333), Expect = 7e-31
 Identities = 128/551 (23%), Positives = 229/551 (41%), Gaps = 64/551 (11%)

Query: 10  DYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFMSAVTVLG 69
           D  V    F +   +G++  +K  +  T   F + GR M++ P+G SL AS + +   +G
Sbjct: 28  DISVIVIYFLVVMAVGLWAMLKTNR-GTIGGFFLAGRDMAWWPMGASLFASNIGSNHYVG 86

Query: 70  TPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFN--KPVRYAA 127
                   G + + F      ++L+   +F+P++ +SG+ +  EYL+ RF   +   Y +
Sbjct: 87  LAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQVYLS 146

Query: 128 TVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWTDAF 187
            +   +  +L     ++A A+ +    G DL+ ++F    +   Y T GGL +V++TD  
Sbjct: 147 ILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIYTDTL 206

Query: 188 QMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGS------------------RLHIFDFD 229
           Q ++M++G   ++       GG+ +  E+  N +                  R   F   
Sbjct: 207 QTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTISASCYTPRADSFHIF 266

Query: 230 VDPLRRHTFWT-ITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLA----LYFNLLGLW 284
            D +     W  I  G   T L  +  NQ  +QRC+  K   H K A     Y  LL ++
Sbjct: 267 RDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIMCAYLKLLPMF 326

Query: 285 IILVCAVFSGLIMYSHF------KDCDPWTSGIISAPDQLMPYFVMEIFATMP-GLPGLF 337
           ++++  + S  I+Y+         +C       +   +   P  V+E+   MP GL GL 
Sbjct: 327 LMVMPGMIS-RILYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLEL---MPQGLRGLM 382

Query: 338 VACAFSGTLSTVASSINALATVTFEDFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSMA- 396
           ++   +  +S++ S  N+ +T+   D         S+K      +   LL  V+      
Sbjct: 383 LSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGRIFVLLLTVVSIVWVP 442

Query: 397 -VAASVMGGVVQASLSIHGMCGGPMLGLFSLGIVFPFVNWKGALGGLLTGITLSFWVAIG 455
            V  S  G ++  + SI    G P+  +F L I    VN +GA  GL+ G+ +     I 
Sbjct: 443 LVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWGLMVGLAMGLIRMIT 502

Query: 456 AFIYPAPASKTWPLPLSTDQCIKSNVTATGPPVLSSRPGIADTWYSISYLYYSAVGCLGC 515
            F Y             T  C+     +  P ++            + YLY+S V   G 
Sbjct: 503 EFAY------------GTGSCL---APSNCPKIIC----------GVHYLYFSIVLFFGS 537

Query: 516 IVAGVIISLIT 526
           ++  + ISL+T
Sbjct: 538 MLVTLGISLLT 548


>gi|4507031 solute carrier family 5 (sodium/glucose cotransporter),
           member 1 [Homo sapiens]
          Length = 664

 Score =  122 bits (307), Expect = 7e-28
 Identities = 132/606 (21%), Positives = 244/606 (40%), Gaps = 90/606 (14%)

Query: 10  DYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFMSAVTVLG 69
           D  +    F +   +G++ A+    + T   F + GR M + P+G SL AS + +   +G
Sbjct: 28  DISIIVIYFVVVMAVGLW-AMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVG 86

Query: 70  TPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFN--KPVRYAA 127
                   G +   F    L ++++   LF+P++ ++G+ +  EYL+ RF   +   Y +
Sbjct: 87  LAGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGQRIQVYLS 146

Query: 128 TVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWTDAF 187
            +  ++         +++ A+ +N   G +L+ ++F    +   Y   GGL AV++TD  
Sbjct: 147 LLSLLLYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYTDTL 206

Query: 188 QMVVMIVGFLTVLIQGSTHAGGFHNVLEQ---------------------STNGSRLHIF 226
           Q V+M+VG L +        GG+   +E+                     +      HIF
Sbjct: 207 QTVIMLVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDGNTTFQEKCYTPRADSFHIF 266

Query: 227 DFDVDPLRRHTFWT-ITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAK----LALYFNLL 281
               DPL     W     G +   L  +  +Q  +QRC+S K   H K    L  Y  L+
Sbjct: 267 R---DPLTGDLPWPGFIFGMSILTLWYWCTDQVIVQRCLSAKNMSHVKGGCILCGYLKLM 323

Query: 282 GLWIILVCAVFSGLIMYSHF-----KDCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGL 336
            ++I+++  + S ++           +C+ +    +   +   P  V+E+     GL GL
Sbjct: 324 PMFIMVMPGMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPN--GLRGL 381

Query: 337 FVACAFSGTLSTVASSINALATVTFEDFVKSCFPHLSDK-LSTWISKGLCLLFGVMCTSM 395
            ++   +  +S++ S  N+ +T+   D         S+K L       + +L G+    +
Sbjct: 382 MLSVMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKELMIAGRLFILVLIGISIAWV 441

Query: 396 AVAASVMGG-VVQASLSIHGMCGGPMLGLFSLGIVFPFVNWKGALGGLLTGITLSFWVAI 454
            +  S   G +     SI    G P+  +F L I +  VN  GA  GL+ G+ +     I
Sbjct: 442 PIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLILGLLIGISRMI 501

Query: 455 GAFIYPAPASKTWPLPLSTDQCIKSNVTATGPPVLSSRPGIADTWYSISYLYYSAVGCLG 514
             F Y             T  C++           S+ P I      + YLY++ +    
Sbjct: 502 TEFAY------------GTGSCMEP----------SNCPTII---CGVHYLYFAIILFAI 536

Query: 515 CIVAGVIISLITGRQRGEDIQPLLIRPVCNLFCFWSKKYKTLCWC-----GVQHDSGTEQ 569
             +  V+ISL+T             +P+ ++  +       LCW        + D   E+
Sbjct: 537 SFITIVVISLLT-------------KPIPDVHLY------RLCWSLRNSKEERIDLDAEE 577

Query: 570 ENLENG 575
           EN++ G
Sbjct: 578 ENIQEG 583


>gi|109659836 solute carrier family 5 (sodium/glucose
           cotransporter), member 10 isoform 2 [Homo sapiens]
          Length = 596

 Score =  122 bits (306), Expect = 1e-27
 Identities = 114/484 (23%), Positives = 214/484 (44%), Gaps = 32/484 (6%)

Query: 7   AVWDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFMSAVT 66
           +V D +V    F ++  +G++ + +  +   +  FL G R M++ P+G SL AS   +  
Sbjct: 17  SVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAG-RDMTWWPIGASLFASSEGSGL 75

Query: 67  VLGTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFN-KPVR- 124
            +G        G +   F     +V+L  + +F+P++  S I +  EY+Q R+  + +R 
Sbjct: 76  FIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRM 135

Query: 125 YAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWT 184
           Y + +  ++       + +YA AL ++   G++ + S   T  +   Y   GGL AV++T
Sbjct: 136 YLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYT 195

Query: 185 DAFQMVVMIVGFLTVLIQGSTHAGGF--------HNVLEQSTNGSRLHIFDFDV-----D 231
           DA Q ++M+VG + + I+     GG+          +  ++   +  H+   D      D
Sbjct: 196 DALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCHLPRTDAMHMFRD 255

Query: 232 PLRRHTFWT-ITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAK----LALYFNLLGLWII 286
           P      WT +T G T      +  +Q  +QR +S +   HAK    LA Y  +L + +I
Sbjct: 256 PHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLPMGLI 315

Query: 287 LVCAVFSGLIMYSHF-----KDCDPWTSGIISAPDQLMPYFVMEIFATMP-GLPGLFVAC 340
           ++  + S  +           +C       +   +   P  VME+   MP GL GL +A 
Sbjct: 316 IMPGMISRALFPDDVGCVVPSECLRACGAEVGCSNIAYPKLVMEL---MPIGLRGLMIAV 372

Query: 341 AFSGTLSTVASSINALATVTFEDFVKSCFPHLSDKLSTWISK-GLCLLFGVMCTSMAVAA 399
             +  +S++ S  N+ +T+   D  +   P   ++    + +  +  L GV    + V  
Sbjct: 373 MLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRLVIVALIGVSVAWIPVLQ 432

Query: 400 SVMGGVVQASL-SIHGMCGGPMLGLFSLGIVFPFVNWKGALGGLLTGITLSFWVAIGAFI 458
               G +   + S+      P+  +F LG+ +   N +GA  GL+ G+ +     +  F+
Sbjct: 433 DSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGLIAGLVVGATRLVLEFL 492

Query: 459 YPAP 462
            PAP
Sbjct: 493 NPAP 496


>gi|109659839 solute carrier family 5 (sodium/glucose
           cotransporter), member 10 isoform 1 [Homo sapiens]
          Length = 612

 Score =  119 bits (297), Expect = 1e-26
 Identities = 117/500 (23%), Positives = 217/500 (43%), Gaps = 48/500 (9%)

Query: 7   AVWDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFMSAVT 66
           +V D +V    F ++  +G++ + +  +   +  FL G R M++ P+G SL AS   +  
Sbjct: 17  SVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAG-RDMTWWPIGASLFASSEGSGL 75

Query: 67  VLGTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFN-KPVR- 124
            +G        G +   F     +V+L  + +F+P++  S I +  EY+Q R+  + +R 
Sbjct: 76  FIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRM 135

Query: 125 YAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWT 184
           Y + +  ++       + +YA AL ++   G++ + S   T  +   Y   GGL AV++T
Sbjct: 136 YLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYT 195

Query: 185 DAFQMVVMIVGFLTVLIQGSTHAGGF--------HNVLEQSTNGSRLHIFDFDV-----D 231
           DA Q ++M+VG + + I+     GG+          +  ++   +  H+   D      D
Sbjct: 196 DALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCHLPRTDAMHMFRD 255

Query: 232 PLRRHTFWT-ITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAK----LALYFNLLGLWII 286
           P      WT +T G T      +  +Q  +QR +S +   HAK    LA Y  +L + +I
Sbjct: 256 PHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLPMGLI 315

Query: 287 LV-----CAVFSGLIMYSHF----------------KDCDPWTSGIISAPDQLMPYFVME 325
           ++      A+F G  +Y                    +C       +   +   P  VME
Sbjct: 316 IMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSNIAYPKLVME 375

Query: 326 IFATMP-GLPGLFVACAFSGTLSTVASSINALATVTFEDFVKSCFPHLSDKLSTWISK-G 383
           +   MP GL GL +A   +  +S++ S  N+ +T+   D  +   P   ++    + +  
Sbjct: 376 L---MPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRLV 432

Query: 384 LCLLFGVMCTSMAVAASVMGGVVQASL-SIHGMCGGPMLGLFSLGIVFPFVNWKGALGGL 442
           +  L GV    + V      G +   + S+      P+  +F LG+ +   N +GA  GL
Sbjct: 433 IVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGL 492

Query: 443 LTGITLSFWVAIGAFIYPAP 462
           + G+ +     +  F+ PAP
Sbjct: 493 IAGLVVGATRLVLEFLNPAP 512


>gi|206597483 solute carrier family 5 (sodium/glucose
           cotransporter), member 9 isoform 2 [Homo sapiens]
          Length = 681

 Score =  112 bits (281), Expect = 8e-25
 Identities = 133/556 (23%), Positives = 230/556 (41%), Gaps = 77/556 (13%)

Query: 9   WDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFMSAVTVL 68
           +D  V    F     +G++ +I+   + T   + + GR MS+ P+G SL +S + +   +
Sbjct: 36  YDISVVVIYFVFVIAVGIWSSIRA-SRGTIGGYFLAGRSMSWWPIGASLMSSNVGSGLFI 94

Query: 69  GTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFN--KPVRYA 126
           G        G +   F     +++L    +F+PV+  +G+ +  +YL+ RF   +   Y 
Sbjct: 95  GLAGTGAAGGLAVGGFEWNATWLLLALGWVFVPVYIAAGVVTMPQYLKKRFGGQRIQVYM 154

Query: 127 ATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWTDA 186
           + +  I+         +++ AL +    G++L+ S     +V   Y   GGL AV++TDA
Sbjct: 155 SVLSLILYIFTKISTDIFSGALFIQMALGWNLYLSTGILLVVTAVYTIAGGLMAVIYTDA 214

Query: 187 FQMVVMIVGFLTVLIQGSTHAGGFHNVLEQ---------STNGSRLHI-----FDFDVDP 232
            Q V+M+ G L ++  G    G +   LEQ         +   +  H+     F    DP
Sbjct: 215 LQTVIMVGGALVLMFLGFQDVGWYPG-LEQRYRQAIPNVTVPNTTCHLPRPDAFHILRDP 273

Query: 233 LRRHTFWT-----ITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAK----LALYFNLLGL 283
           +     W      +TV  T+ W      +Q  +QR +S K+  HAK    L  Y  +L +
Sbjct: 274 VSGDIPWPGLIFGLTVLATWCWC----TDQVIVQRSLSAKSLSHAKGGSVLGGYLKILPM 329

Query: 284 WIILVCAVFSGLIMYSHFKD---------CDPWTSGIISAPDQLMPYFVMEIFATMP-GL 333
           + I    V  G+I  + F D         C       +   +   P  VM   A MP GL
Sbjct: 330 FFI----VMPGMISRALFPDEVGCVDPDVCQRICGARVGCSNIAYPKLVM---ALMPVGL 382

Query: 334 PGLFVACAFSGTLSTVASSINALATVTFEDFVKSCFPHLSDKLSTWISKGLCLLFGVMCT 393
            GL +A   +  +S++ S  N+ +T+ F   V   F   S +    +   + ++F V+ +
Sbjct: 383 RGLMIAVIMAALMSSLTSIFNSSSTL-FTIDVWQRFRRKSTEQELMVVGRVFVVFLVVIS 441

Query: 394 SM---AVAASVMGGVVQASLSIHGMCGGPMLGLFSLGIVFPFVNWKGALGGLLTGITLSF 450
            +    + +S  G +     ++      P+  LF L I    V   GA  GL+ G+ +  
Sbjct: 442 ILWIPIIQSSNSGQLFDYIQAVTSYLAPPITALFLLAIFCKRVTEPGAFWGLVFGLGVGL 501

Query: 451 WVAIGAFIYPAPASKTWPLPLSTDQCIKSNVTATGPPVLSSRPGIADTWYSISYLYYSAV 510
              I  F YPAPA                         +  RP +   ++   YLY++ +
Sbjct: 502 LRMILEFSYPAPACGE----------------------VDRRPAVLKDFH---YLYFAIL 536

Query: 511 GCLGCIVAGVIISLIT 526
            C    +  VI+SL T
Sbjct: 537 LCGLTAIVIVIVSLCT 552


>gi|110835708 solute carrier family 5 (inositol transporters),
           member 3 [Homo sapiens]
          Length = 718

 Score =  111 bits (278), Expect = 2e-24
 Identities = 145/632 (22%), Positives = 256/632 (40%), Gaps = 77/632 (12%)

Query: 12  VVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFMSAVTVLGTP 71
           +   AL+FI      FFA+ +  ++T   + + GR M++  +G SL  S + +   +G  
Sbjct: 10  IAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNIGSEHFIGLA 69

Query: 72  SEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRF--NKPVRYAATV 129
                 G +   +    L ++ L   +F+P++ RSG+ +  EYL  RF  ++   Y A +
Sbjct: 70  GSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFAAL 129

Query: 130 IYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWTDAFQM 189
             I+       V +Y+ AL + +  G++L+ SV     +       GGL AV++TD  Q 
Sbjct: 130 SLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQA 189

Query: 190 VVMIVGFLTVLIQGSTHAGGFHNVLEQ------------------STNGSRLHIFDFDVD 231
           ++MI+G LT++I      GGF  V  +                  +TN   +      + 
Sbjct: 190 LLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNVSPKKEALK 249

Query: 232 PLRRHTF----WT-ITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAK----LALYFNLLG 282
            LR  T     W    +G T   +  +  +Q  +QR ++ K   HAK    +A +  LL 
Sbjct: 250 MLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLP 309

Query: 283 LWIILVCAVFSGLIMYSHFKDCDPWTSGII-----SAPDQLMPYFVMEIFATMPGLPGLF 337
           ++II+V  + S ++        +P    ++        +   P  VM++     GL GL 
Sbjct: 310 MFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLVPV--GLRGLM 367

Query: 338 VACAFSGTLSTVASSINALATVTFEDFVKSCFPHLSDKLSTWISKGLCLLFGVMCTS-MA 396
           +A   +  +S + S  N+ +T+   D  K      S +    + +       V+  + + 
Sbjct: 368 MAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVISIAWVP 427

Query: 397 VAASVMGGVVQASL-SIHGMCGGPMLGLFSLGIVFPFVNWKGALGGLLTGITLSFWVAIG 455
           +   + GG +   +  +      P+  LF L I +   N +GA  G + G  L     I 
Sbjct: 428 IIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLGAVRLIL 487

Query: 456 AFIYPAPASKTWPLPLSTDQCIKSNVTATGPPVLSSRPGIADTWYSISYLYYSAVGCLGC 515
           AF Y AP            +C + +          +RPG       I Y+Y +       
Sbjct: 488 AFAYRAP------------ECDQPD----------NRPGFIK---DIHYMYVATGLFWVT 522

Query: 516 IVAGVIISLITGRQRGEDIQPLLIRPVCNLFCFWSKKYKTLCW-CGVQHDSGTEQE-NLE 573
            +  VI+SL+T     E I+            FWSKK   +   C  + +    QE ++ 
Sbjct: 523 GLITVIVSLLTPPPTKEQIRTT---------TFWSKKNLVVKENCSPKEEPYQMQEKSIL 573

Query: 574 NGSARKQGAESVLQNGLRRESLVHVPGYDPKD 605
             S   +    ++ NG   +S   + G  P+D
Sbjct: 574 RCSENNETINHIIPNGKSEDS---IKGLQPED 602


>gi|4507033 solute carrier family 5 (sodium/glucose cotransporter),
           member 2 [Homo sapiens]
          Length = 672

 Score =  107 bits (266), Expect = 4e-23
 Identities = 115/487 (23%), Positives = 212/487 (43%), Gaps = 42/487 (8%)

Query: 10  DYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFMSAVTVLG 69
           D +V AA F +  G+G++   +  +      FL G R M + PVG SL AS + +   +G
Sbjct: 25  DILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAG-RSMVWWPVGASLFASNIGSGHFVG 83

Query: 70  TPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRF-NKPVR-YAA 127
                   G +   F    LFV+LL   LF PV+  +G+ +  +YL+ RF  + +R Y +
Sbjct: 84  LAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFGGRRIRLYLS 143

Query: 128 TVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWTDAF 187
            +   +       V +++ A+ + Q  G++++ SV A   +   Y   GGL A+++TD  
Sbjct: 144 VLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMYTDTV 203

Query: 188 QMVVMIVGFLTVLIQGSTHAGGFHNVLEQ----------STNGSRLHIFDFDVDP----- 232
           Q  V++ G   ++       GG+  + ++          S + +  +I  F   P     
Sbjct: 204 QTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSLTVSEDPAVGNISSFCYRPRPDSY 263

Query: 233 -LRRHTF-----WTITVGGTFTWLGIYGV-NQSTIQRCISCKTEKHAK----LALYFNLL 281
            L RH       W   + G     G Y   +Q  +QRC++ K+  H K    L  Y  L 
Sbjct: 264 HLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLTHIKAGCILCGYLKLT 323

Query: 282 GLWIILVCAVFSGLIMYSHF-----KDCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGL 336
            ++++++  + S ++          + C       +   +   P  V+++     GL GL
Sbjct: 324 PMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVGCSNIAYPRLVVKLMPN--GLRGL 381

Query: 337 FVACAFSGTLSTVASSINALATVTFEDFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSMA 396
            +A   +  +S++AS  N+ +T+   D      P   D+    + + L ++F ++  S+A
Sbjct: 382 MLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGR-LWVVF-IVVVSVA 439

Query: 397 ----VAASVMGGVVQASLSIHGMCGGPMLGLFSLGIVFPFVNWKGALGGLLTGITLSFWV 452
               V A+  G +     ++      P+  +F L +  P VN +GA  GL+ G+ +    
Sbjct: 440 WLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFWGLIGGLLMGLAR 499

Query: 453 AIGAFIY 459
            I  F +
Sbjct: 500 LIPEFSF 506


>gi|206597487 solute carrier family 5 (sodium/glucose
           cotransporter), member 9 isoform 1 [Homo sapiens]
          Length = 706

 Score = 99.8 bits (247), Expect = 7e-21
 Identities = 133/581 (22%), Positives = 230/581 (39%), Gaps = 102/581 (17%)

Query: 9   WDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFMSAVTVL 68
           +D  V    F     +G++ +I+   + T   + + GR MS+ P+G SL +S + +   +
Sbjct: 36  YDISVVVIYFVFVIAVGIWSSIRA-SRGTIGGYFLAGRSMSWWPIGASLMSSNVGSGLFI 94

Query: 69  GTPSEVYRFGASFLVFF-------------------------IAYLFVILLTSELFLPVF 103
           G        G +   F                              +++L    +F+PV+
Sbjct: 95  GLAGTGAAGGLAVGGFEWNMRKSRSGGDRGIHPRSHGRTGVRSQATWLLLALGWVFVPVY 154

Query: 104 YRSGITSTYEYLQLRFN--KPVRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGS 161
             +G+ +  +YL+ RF   +   Y + +  I+         +++ AL +    G++L+ S
Sbjct: 155 IAAGVVTMPQYLKKRFGGQRIQVYMSVLSLILYIFTKISTDIFSGALFIQMALGWNLYLS 214

Query: 162 VFATGIVCTFYCTLGGLKAVVWTDAFQMVVMIVGFLTVLIQGSTHAGGFHNVLEQ----- 216
                +V   Y   GGL AV++TDA Q V+M+ G L ++  G    G +   LEQ     
Sbjct: 215 TGILLVVTAVYTIAGGLMAVIYTDALQTVIMVGGALVLMFLGFQDVGWYPG-LEQRYRQA 273

Query: 217 ----STNGSRLHI-----FDFDVDPLRRHTFWT-----ITVGGTFTWLGIYGVNQSTIQR 262
               +   +  H+     F    DP+     W      +TV  T+ W      +Q  +QR
Sbjct: 274 IPNVTVPNTTCHLPRPDAFHILRDPVSGDIPWPGLIFGLTVLATWCWC----TDQVIVQR 329

Query: 263 CISCKTEKHAK----LALYFNLLGLWIILVCAVFSGLIMYSHFKD---------CDPWTS 309
            +S K+  HAK    L  Y  +L ++ I    V  G+I  + F D         C     
Sbjct: 330 SLSAKSLSHAKGGSVLGGYLKILPMFFI----VMPGMISRALFPDEVGCVDPDVCQRICG 385

Query: 310 GIISAPDQLMPYFVMEIFATMP-GLPGLFVACAFSGTLSTVASSINALATVTFEDFVKSC 368
             +   +   P  VM   A MP GL GL +A   +  +S++ S  N+ +T+ F   V   
Sbjct: 386 ARVGCSNIAYPKLVM---ALMPVGLRGLMIAVIMAALMSSLTSIFNSSSTL-FTIDVWQR 441

Query: 369 FPHLSDKLSTWISKGLCLLFGVMCTSM---AVAASVMGGVVQASLSIHGMCGGPMLGLFS 425
           F   S +    +   + ++F V+ + +    + +S  G +     ++      P+  LF 
Sbjct: 442 FRRKSTEQELMVVGRVFVVFLVVISILWIPIIQSSNSGQLFDYIQAVTSYLAPPITALFL 501

Query: 426 LGIVFPFVNWKGALGGLLTGITLSFWVAIGAFIYPAPASKTWPLPLSTDQCIKSNVTATG 485
           L I    V   GA  GL+ G+ +     I  F YPAPA                      
Sbjct: 502 LAIFCKRVTEPGAFWGLVFGLGVGLLRMILEFSYPAPACGE------------------- 542

Query: 486 PPVLSSRPGIADTWYSISYLYYSAVGCLGCIVAGVIISLIT 526
              +  RP +   ++   YLY++ + C    +  VI+SL T
Sbjct: 543 ---VDRRPAVLKDFH---YLYFAILLCGLTAIVIVIVSLCT 577


>gi|11141885 solute carrier family 5 (choline transporter), member 7
           [Homo sapiens]
          Length = 580

 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 93/459 (20%), Positives = 183/459 (39%), Gaps = 47/459 (10%)

Query: 12  VVFAALFFISSGIGVFFAIKERKKATSRE----FLVGGRQMSFGPVGLSLTASFMSAVTV 67
           +VF  L  +   +G++ A + +   ++ E     +VGGR +     G ++TA+++    +
Sbjct: 12  IVFYLLILL---VGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYI 68

Query: 68  LGTPSEVY--RFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFNKPVRY 125
            GT   VY   +G ++    I Y   ++L    F       G  +  +  Q  + K +  
Sbjct: 69  NGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGG 128

Query: 126 AATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWTD 185
              +  ++  + +   +  A    ++ +   D+  SV  + ++ T Y  +GGL +V +TD
Sbjct: 129 LLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGGLYSVAYTD 188

Query: 186 AFQMVVMIVGFLTVLIQGSTHAG----GFHNVLEQSTNGSRLHIFDFDVDPLRRHTFWTI 241
             Q+  + VG    +    +H      GF   +        L   D         +F  +
Sbjct: 189 VVQLFCIFVGLWISVPFALSHPAVADIGF-TAVHAKYQKPWLGTVDSSEVYSWLDSFLLL 247

Query: 242 TVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCAVFSGLIMYSHF 301
            +GG   W       Q+  QR +S  +  +A++  +    G  ++ + A+  G I  S  
Sbjct: 248 MLGG-IPW-------QAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGAS-- 297

Query: 302 KDCDPWTSGIISAP--------DQLMP---YFVMEIFATMPGLPGLFVACAFSGTLSTVA 350
                W       P        D ++P    ++  ++ +  GL G   A   S   S++ 
Sbjct: 298 ---TDWNQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGL-GAVSAAVMSSADSSIL 353

Query: 351 SSINALATVTFEDFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSMAVAASVMGGVVQASL 410
           S+ +  A   ++    S   + SDK   W+ +    +FG   T+MA+    + G+   S 
Sbjct: 354 SASSMFARNIYQ---LSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSS 410

Query: 411 SIHGMCGGPMLGLFSLGIVF-PFVNWKGALGGLLTGITL 448
            +  +   P L    L ++F    N  GA+ G ++G+ L
Sbjct: 411 DLVYIVIFPQL----LCVLFVKGTNTYGAVAGYVSGLFL 445


>gi|27734719 solute carrier family 19, member 2 [Homo sapiens]
          Length = 497

 Score = 31.6 bits (70), Expect = 2.3
 Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 13/117 (11%)

Query: 49  SFGPVGLSLTASFMSA-VTVLGTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSG 107
           ++G + LSL +  ++A V ++ T   ++   AS++VF I Y+ +I + +       ++  
Sbjct: 360 TWGEMTLSLFSLLIAAAVYIMDTVGNIWVCYASYVVFRIIYMLLITIAT-------FQIA 412

Query: 108 ITSTYEYLQLRFNKPVRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFA 164
              + E   L F        T I +    L T +VV A  L L   T F ++ S FA
Sbjct: 413 ANLSMERYALVFG-----VNTFIALALQTLLTLIVVDASGLGLEITTQFLIYASYFA 464


>gi|239582720 ATG9 autophagy related 9 homolog B [Homo sapiens]
          Length = 924

 Score = 31.2 bits (69), Expect = 3.0
 Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 1/75 (1%)

Query: 475 QCIKSNVTATGPPVLSSRPGIADTWYSISYLYYSAVGCLGCIVAGVIISLITGRQRGEDI 534
           +C+  NV     P   +RPG   +  ++S     +  C   I +  ++ L+     G  +
Sbjct: 234 RCVDYNVLFANQPSNHTRPGPFHSKVTLSDAILPSAQCAERIRSSPLLVLLLVLAAGFWL 293

Query: 535 QPLLIRPVCNLFCFW 549
             LL R VCNLF +W
Sbjct: 294 VQLL-RSVCNLFSYW 307


>gi|6005715 solute carrier family 6 (amino acid transporter), member
           14 [Homo sapiens]
          Length = 642

 Score = 31.2 bits (69), Expect = 3.0
 Identities = 61/270 (22%), Positives = 106/270 (39%), Gaps = 44/270 (16%)

Query: 139 TGVVVYAPALALNQ---VTGFDLWGSVFATGIVCTFYCTLGGLKAVVWTDAFQMVVMIVG 195
           TGV+V+  AL L     + G  L+  + ++G            K V +T  F  VV+++ 
Sbjct: 232 TGVIVWYLALCLLLAWLIVGAALFKGIKSSG------------KVVYFTALFPYVVLLI- 278

Query: 196 FLTVLIQGSTHAG---GFHNVLEQSTNGSRLHIFDFDVDPLRRHTFWTITVG-GTFTWLG 251
              +L++G+T  G   G    +   +N ++L   +   D   +  F++++V  G    L 
Sbjct: 279 ---LLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQ-IFYSLSVAWGGLVALS 334

Query: 252 IYGV--NQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCAVFSGLIMYSHFKDCDPWTS 309
            Y    N       + C T     +   F           A+FS L   +H    +   S
Sbjct: 335 SYNKFKNNCFSDAIVVCLTNCLTSVFAGF-----------AIFSILGHMAHISGKE--VS 381

Query: 310 GIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASSINALATVTFEDFVKSCF 369
            ++ +   L      E  A +PG P  F +  F   L T+       +  T    ++  F
Sbjct: 382 QVVKSGFDLAFIAYPEALAQLPGGP--FWSILFFFMLLTLGLDSQFASIETITTTIQDLF 439

Query: 370 PHLSDKLSTWISKGLCL---LFGVMCTSMA 396
           P +  K+   I+ G CL   L G++C + A
Sbjct: 440 PKVMKKMRVPITLGCCLVLFLLGLVCVTQA 469


>gi|31543630 solute carrier family 20 (phosphate transporter),
           member 1 [Homo sapiens]
          Length = 679

 Score = 31.2 bits (69), Expect = 3.0
 Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 13/62 (20%)

Query: 122 PVRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAV 181
           PV YA TV   + +I+YTG    AP L  +++    LWG++  + + C  +C L     +
Sbjct: 199 PVFYACTVGINLFSIMYTG----APLLGFDKL---PLWGTILIS-VGCAVFCAL-----I 245

Query: 182 VW 183
           VW
Sbjct: 246 VW 247


>gi|14249528 solute carrier family 35, member B4 [Homo sapiens]
          Length = 331

 Score = 30.0 bits (66), Expect = 6.6
 Identities = 35/164 (21%), Positives = 63/164 (38%), Gaps = 17/164 (10%)

Query: 231 DPLRRHTFWTITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCA 290
           D  +   +W + +G   T+  +        Q  +  +  KH+K AL++N     + L   
Sbjct: 152 DGFQAFVWWLLGIGA-LTFALLMSARMGIFQETLYKRFGKHSKEALFYNHA---LPLPGF 207

Query: 291 VFSGLIMYSH---FKDCDPWTSGIISAPDQLM-PYFVMEIFATMPGLPGLFVACAFSGTL 346
           VF    +Y H   F   + +   +I     +M  Y +M I      + G+F+       L
Sbjct: 208 VFLASDIYDHAVLFNKSELYEIPVIGVTLPIMWFYLLMNIITQYVCIRGVFI-------L 260

Query: 347 STVASSINALATVTFEDFVKSCFP--HLSDKLSTWISKGLCLLF 388
           +T  +S+     VT   FV   F   +  +  + W   G   +F
Sbjct: 261 TTECASLTVTLVVTLRKFVSLIFSILYFQNPFTLWHWLGTLFVF 304


>gi|53828710 olfactory receptor, family 5, subfamily D, member 16
           [Homo sapiens]
          Length = 328

 Score = 30.0 bits (66), Expect = 6.6
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 11/117 (9%)

Query: 299 SHFKDCDPWTSGIISAPDQLMPYFVMEIFATMPG-LPGLFVACAFSGTLSTVASSINALA 357
           +H    D   S II AP  L+   V +   +  G L   F  C F      V + +   A
Sbjct: 66  NHLSFVDFCYSSII-APMMLVNLVVEDRTISFSGCLVQFFFFCTF------VVTELILFA 118

Query: 358 TVTFEDFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSMAVAASVMGGVVQASLSIHG 414
            + ++ FV  C P L    +  IS+ LC +  V+  +  VA S+        LS HG
Sbjct: 119 VMAYDHFVAICNPLL---YTVAISQKLCAMLVVVLYAWGVACSLTLACSALKLSFHG 172


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.140    0.447 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,439,877
Number of Sequences: 37866
Number of extensions: 978553
Number of successful extensions: 2644
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2589
Number of HSP's gapped (non-prelim): 24
length of query: 618
length of database: 18,247,518
effective HSP length: 108
effective length of query: 510
effective length of database: 14,157,990
effective search space: 7220574900
effective search space used: 7220574900
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.