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Search of human proteins with 157502195
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157502195 proteasome 26S non-ATPase subunit 13 isoform 2
[Homo sapiens]
(378 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157502195 proteasome 26S non-ATPase subunit 13 isoform 2 [Hom... 755 0.0
gi|157502193 proteasome 26S non-ATPase subunit 13 isoform 1 [Hom... 661 0.0
gi|7705330 COP9 complex subunit 7a [Homo sapiens] 39 0.006
gi|23397429 eukaryotic translation initiation factor 3, subunit ... 37 0.029
gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo sa... 37 0.029
gi|38373690 COP9 signalosome subunit 4 [Homo sapiens] 31 2.1
gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo sa... 31 2.1
gi|46358428 selective LIM binding factor homolog [Homo sapiens] 30 2.7
gi|219842262 COP9 constitutive photomorphogenic homolog subunit ... 30 3.6
gi|4759264 COP9 constitutive photomorphogenic homolog subunit 2 ... 30 3.6
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap... 30 4.7
gi|239740963 PREDICTED: similar to N-ethylmaleimide-sensitive fa... 29 6.1
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] 29 6.1
gi|40548372 tetratricopeptide repeat domain 15 [Homo sapiens] 29 8.0
gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens] 29 8.0
gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens] 29 8.0
gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens] 29 8.0
gi|6679189 transmembrane emp24 domain containing 3 [Homo sapiens] 29 8.0
>gi|157502195 proteasome 26S non-ATPase subunit 13 isoform 2 [Homo
sapiens]
Length = 378
Score = 755 bits (1949), Expect = 0.0
Identities = 378/378 (100%), Positives = 378/378 (100%)
Query: 1 MKDVPGFLQQSQNSGPGQPAVWHRLEELYTKNFMKTLSVNLNTGKSLSSVFHFENECIDA 60
MKDVPGFLQQSQNSGPGQPAVWHRLEELYTKNFMKTLSVNLNTGKSLSSVFHFENECIDA
Sbjct: 1 MKDVPGFLQQSQNSGPGQPAVWHRLEELYTKNFMKTLSVNLNTGKSLSSVFHFENECIDA 60
Query: 61 RRCSKAGGFYFRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAI 120
RRCSKAGGFYFRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAI
Sbjct: 61 RRCSKAGGFYFRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAI 120
Query: 121 GALKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALR 180
GALKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALR
Sbjct: 121 GALKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALR 180
Query: 181 FLGCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNTDRQWLIDTLY 240
FLGCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNTDRQWLIDTLY
Sbjct: 181 FLGCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNTDRQWLIDTLY 240
Query: 241 AFNSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAK 300
AFNSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAK
Sbjct: 241 AFNSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAK 300
Query: 301 SAKITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLEFWCT 360
SAKITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLEFWCT
Sbjct: 301 SAKITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLEFWCT 360
Query: 361 DVKSMEMLVEHQAHDILT 378
DVKSMEMLVEHQAHDILT
Sbjct: 361 DVKSMEMLVEHQAHDILT 378
>gi|157502193 proteasome 26S non-ATPase subunit 13 isoform 1 [Homo
sapiens]
Length = 376
Score = 661 bits (1706), Expect = 0.0
Identities = 344/388 (88%), Positives = 351/388 (90%), Gaps = 22/388 (5%)
Query: 1 MKDVPGFLQQSQNSGPGQPAVWHRLEELYTKNFMKTLSVNL---------NTGKSLSSVF 51
MKDVPGFLQQSQNSGPGQPAVWHRLEELYTK L++ + G L ++
Sbjct: 1 MKDVPGFLQQSQNSGPGQPAVWHRLEELYTKKLWHQLTLQVLDFVQDPCFAQGDGLIKLY 60
Query: 52 -HFENECIDARRCSKAGGFYFRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSD 110
+F +E F RVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSD
Sbjct: 61 ENFISE------------FEHRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSD 108
Query: 111 EAVILCKTAIGALKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGN 170
EAVILCKTAIGALKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGN
Sbjct: 109 EAVILCKTAIGALKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGN 168
Query: 171 HASYYKDALRFLGCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNT 230
HASYYKDALRFLGCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNT
Sbjct: 169 HASYYKDALRFLGCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNT 228
Query: 231 DRQWLIDTLYAFNSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANH 290
DRQWLIDTLYAFNSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANH
Sbjct: 229 DRQWLIDTLYAFNSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANH 288
Query: 291 RQLTFEEIAKSAKITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKG 350
RQLTFEEIAKSAKITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKG
Sbjct: 289 RQLTFEEIAKSAKITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKG 348
Query: 351 MKDRLEFWCTDVKSMEMLVEHQAHDILT 378
MKDRLEFWCTDVKSMEMLVEHQAHDILT
Sbjct: 349 MKDRLEFWCTDVKSMEMLVEHQAHDILT 376
>gi|7705330 COP9 complex subunit 7a [Homo sapiens]
Length = 275
Score = 39.3 bits (90), Expect = 0.006
Identities = 37/162 (22%), Positives = 69/162 (42%), Gaps = 9/162 (5%)
Query: 211 GVFNFGELLMHPVLESLRNTDRQWLIDTLYAFNSGNVERFQTLKTAWGQQPDLAANEAQL 270
GV+ FGELL P + L +D L F G + P L +
Sbjct: 39 GVYVFGELLDMPNVRELAESDFASTFRLLTVFAYGTYADYLAEAR---NLPPLTEAQKNK 95
Query: 271 LRKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVNEVELLVMKALSVGLVKGSIDEVD 330
LR + ++ L P + E +A V ++E LV++A+ +++GS+D+ +
Sbjct: 96 LRHLSVVTLAAKVKCIPY---AVLLEALALR---NVRQLEDLVIEAVYADVLRGSLDQRN 149
Query: 331 KRVHMTWVQPRVLDLQQIKGMKDRLEFWCTDVKSMEMLVEHQ 372
+R+ + + R + Q + + L+ WC + + +E Q
Sbjct: 150 QRLEVDYSIGRDIQRQDLSAIARTLQEWCVGCEVVLSGIEEQ 191
>gi|23397429 eukaryotic translation initiation factor 3, subunit M
[Homo sapiens]
Length = 374
Score = 37.0 bits (84), Expect = 0.029
Identities = 22/90 (24%), Positives = 46/90 (51%), Gaps = 4/90 (4%)
Query: 269 QLLRKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVNEVELLVMKALSVGLVKGSIDE 328
Q + K++LL M M +++++F+ + + +I ++VE V+ A+ +V ID+
Sbjct: 272 QNMAKMRLLTFMGMA----VENKEISFDTMQQELQIGADDVEAFVIDAVRTKMVYCKIDQ 327
Query: 329 VDKRVHMTWVQPRVLDLQQIKGMKDRLEFW 358
++V ++ R QQ + + D L W
Sbjct: 328 TQRKVVVSHSTHRTFGKQQWQQLYDTLNAW 357
>gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo
sapiens]
Length = 1287
Score = 37.0 bits (84), Expect = 0.029
Identities = 36/142 (25%), Positives = 61/142 (42%), Gaps = 18/142 (12%)
Query: 210 EGVFNFGELLMHPVLESLRNTDRQWLIDTLYAFNS--------GNVER-----FQTLKTA 256
E +++ L +LE LRN +++ A S G V F+ +
Sbjct: 31 EEIWSLLFLAAEQLLEDLRNDSSDYVVCPWSALLSAAGSLSFQGRVSHIEAAPFKAPELL 90
Query: 257 WGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVNEVELLVMKA 316
GQ D + +Q L+ + L + +T HR+ T + + ++ ++ EV + A
Sbjct: 91 QGQSEDEQPDASQPLQLCEPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAPA 150
Query: 317 -----LSVGLVKGSIDEVDKRV 333
VGLV G+I EV+KRV
Sbjct: 151 GLHIRRLVGLVLGTISEVEKRV 172
>gi|38373690 COP9 signalosome subunit 4 [Homo sapiens]
Length = 406
Score = 30.8 bits (68), Expect = 2.1
Identities = 13/45 (28%), Positives = 25/45 (55%)
Query: 290 HRQLTFEEIAKSAKITVNEVELLVMKALSVGLVKGSIDEVDKRVH 334
+ +TFEE+ +I + E + + ++ G + G ID++D VH
Sbjct: 316 YNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVH 360
>gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo
sapiens]
Length = 1309
Score = 30.8 bits (68), Expect = 2.1
Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 5/57 (8%)
Query: 282 MTFTRPANHRQLTFEEIAKSAKITVNEVELLVMKA-----LSVGLVKGSIDEVDKRV 333
+T HR+ T + + ++ ++ EV + A VGLV G+I EV+KRV
Sbjct: 138 LTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAPAGLHIRRLVGLVLGTISEVEKRV 194
>gi|46358428 selective LIM binding factor homolog [Homo sapiens]
Length = 1749
Score = 30.4 bits (67), Expect = 2.7
Identities = 13/31 (41%), Positives = 18/31 (58%)
Query: 221 HPVLESLRNTDRQWLIDTLYAFNSGNVERFQ 251
HP LE LR + QWL+DT +G ++ Q
Sbjct: 733 HPALEKLRRSYYQWLMDTQQEERAGELQESQ 763
>gi|219842262 COP9 constitutive photomorphogenic homolog subunit 2
isoform 2 [Homo sapiens]
Length = 450
Score = 30.0 bits (66), Expect = 3.6
Identities = 32/134 (23%), Positives = 62/134 (46%), Gaps = 17/134 (12%)
Query: 241 AFNSGNVERFQT-LKTAWGQ---QPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFE 296
A+ + ++ F+ LKT P + + +LLR I+ L+++ +P + F
Sbjct: 324 AYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLI--KPYTRIHIPF- 380
Query: 297 EIAKSAKITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMK-DRL 355
I+K I V +VE L+++ + + G ID+V++ + LD Q+ G + L
Sbjct: 381 -ISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLE--------LDHQKRGGARYTAL 431
Query: 356 EFWCTDVKSMEMLV 369
+ W + S+ V
Sbjct: 432 DKWTNQLNSLNQAV 445
>gi|4759264 COP9 constitutive photomorphogenic homolog subunit 2
isoform 1 [Homo sapiens]
Length = 443
Score = 30.0 bits (66), Expect = 3.6
Identities = 32/134 (23%), Positives = 62/134 (46%), Gaps = 17/134 (12%)
Query: 241 AFNSGNVERFQT-LKTAWGQ---QPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFE 296
A+ + ++ F+ LKT P + + +LLR I+ L+++ +P + F
Sbjct: 317 AYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLI--KPYTRIHIPF- 373
Query: 297 EIAKSAKITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMK-DRL 355
I+K I V +VE L+++ + + G ID+V++ + LD Q+ G + L
Sbjct: 374 -ISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLE--------LDHQKRGGARYTAL 424
Query: 356 EFWCTDVKSMEMLV 369
+ W + S+ V
Sbjct: 425 DKWTNQLNSLNQAV 438
>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
sapiens]
Length = 955
Score = 29.6 bits (65), Expect = 4.7
Identities = 28/127 (22%), Positives = 62/127 (48%), Gaps = 9/127 (7%)
Query: 259 QQPDLAANEAQLLRKIQLLC--LMEMTFTRPANHRQLTF--EEIAKSAKI--TVNEVELL 312
Q+ L +A+L R Q+ C L E+ R H++ + ++ K+ T + ++
Sbjct: 430 QRQKLIQEKAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTKYDADIN 489
Query: 313 VMK---ALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLEFWCTDVKSMEMLV 369
++K ALS I+E+++ V Q + +LQ+ + ++D+ + + ++ +
Sbjct: 490 LLKQEHALSASKASSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIY 549
Query: 370 EHQAHDI 376
E +AHD+
Sbjct: 550 EKKAHDL 556
>gi|239740963 PREDICTED: similar to N-ethylmaleimide-sensitive
factor [Homo sapiens]
Length = 405
Score = 29.3 bits (64), Expect = 6.1
Identities = 16/57 (28%), Positives = 28/57 (49%), Gaps = 1/57 (1%)
Query: 220 MHPVLESLRNTDRQWLIDTLYAFNSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQL 276
+ P LE+ RN +W+ + + S +++ + K WG P L E+ RK+ L
Sbjct: 339 LDPALEATRNVSMRWVDNAVTVEFSPCLKQLSSPKPKWG-SPSLEGYESNERRKLNL 394
>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
Length = 4646
Score = 29.3 bits (64), Expect = 6.1
Identities = 32/137 (23%), Positives = 54/137 (39%), Gaps = 25/137 (18%)
Query: 247 VERFQTLKTAWGQ-------------QPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQL 293
+E Q LK W + QP ++ +L + + L +F PA RQ
Sbjct: 1323 LEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSF--PARLRQY 1380
Query: 294 TFEEIAKSAKITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMKD 353
E + ++ +LV++ S L ++ KR+H+ WV L L QI
Sbjct: 1381 ASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSE-LTLGQI----- 1434
Query: 354 RLEFWCTDVKSMEMLVE 370
W D++ E +V+
Sbjct: 1435 ----WDVDLQKNEAIVK 1447
>gi|40548372 tetratricopeptide repeat domain 15 [Homo sapiens]
Length = 735
Score = 28.9 bits (63), Expect = 8.0
Identities = 11/33 (33%), Positives = 21/33 (63%)
Query: 118 TAIGALKLNIGDLQVTKETIEDVEEMLNNLPGV 150
+ IG + L IGD++ ++ +DVE++ L G+
Sbjct: 584 SGIGRISLQIGDIKTAEKYFQDVEKVTQKLDGL 616
>gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 28.9 bits (63), Expect = 8.0
Identities = 28/117 (23%), Positives = 46/117 (39%), Gaps = 7/117 (5%)
Query: 101 KTREKVKSSDEAVILCKTAIGALKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYD- 159
K + ++K+ + ++ K + +L K+TIE+ EE L N + Y+
Sbjct: 716 KQQWEMKTEEADLLQTKLQQSSYHKQQEELDALKKTIEESEETLKNTKEIQRKAEEKYEV 775
Query: 160 LSSKYYQTIGNHASYYKDALRFLGC------VDIKDLPVSEQQERAFTLGLAGLLGE 210
L +K KDA + L C K + +Q+ A TL L L E
Sbjct: 776 LENKMKNAEAERERELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKRE 832
>gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 28.9 bits (63), Expect = 8.0
Identities = 28/117 (23%), Positives = 46/117 (39%), Gaps = 7/117 (5%)
Query: 101 KTREKVKSSDEAVILCKTAIGALKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYD- 159
K + ++K+ + ++ K + +L K+TIE+ EE L N + Y+
Sbjct: 716 KQQWEMKTEEADLLQTKLQQSSYHKQQEELDALKKTIEESEETLKNTKEIQRKAEEKYEV 775
Query: 160 LSSKYYQTIGNHASYYKDALRFLGC------VDIKDLPVSEQQERAFTLGLAGLLGE 210
L +K KDA + L C K + +Q+ A TL L L E
Sbjct: 776 LENKMKNAEAERERELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKRE 832
>gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 28.9 bits (63), Expect = 8.0
Identities = 28/117 (23%), Positives = 46/117 (39%), Gaps = 7/117 (5%)
Query: 101 KTREKVKSSDEAVILCKTAIGALKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYD- 159
K + ++K+ + ++ K + +L K+TIE+ EE L N + Y+
Sbjct: 716 KQQWEMKTEEADLLQTKLQQSSYHKQQEELDALKKTIEESEETLKNTKEIQRKAEEKYEV 775
Query: 160 LSSKYYQTIGNHASYYKDALRFLGC------VDIKDLPVSEQQERAFTLGLAGLLGE 210
L +K KDA + L C K + +Q+ A TL L L E
Sbjct: 776 LENKMKNAEAERERELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKRE 832
>gi|6679189 transmembrane emp24 domain containing 3 [Homo sapiens]
Length = 217
Score = 28.9 bits (63), Expect = 8.0
Identities = 13/38 (34%), Positives = 22/38 (57%)
Query: 270 LLRKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVN 307
LLR+ + C E+TF P N +Q EE+ + K +++
Sbjct: 17 LLRRAEQPCGAELTFELPDNAKQCFHEEVEQGVKFSLD 54
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,938,203
Number of Sequences: 37866
Number of extensions: 507593
Number of successful extensions: 1281
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1269
Number of HSP's gapped (non-prelim): 19
length of query: 378
length of database: 18,247,518
effective HSP length: 104
effective length of query: 274
effective length of database: 14,309,454
effective search space: 3920790396
effective search space used: 3920790396
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.