Guide to the Human Genome
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Search of human proteins with 157384994

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157384994 hypothetical protein LOC136157 [Homo sapiens]
         (194 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157384994 hypothetical protein LOC136157 [Homo sapiens]            400   e-112
gi|7661832 Ssu72 RNA polymerase II CTD phosphatase homolog [Homo...   289   1e-78
gi|169217206 PREDICTED: similar to Ssu72 RNA polymerase II CTD p...   268   2e-72
gi|89060983 PREDICTED: similar to Ssu72 RNA polymerase II CTD ph...   268   2e-72
gi|27486601 PREDICTED: similar to Ssu72 RNA polymerase II CTD ph...   268   2e-72
gi|54859722 nucleoporin 160kDa [Homo sapiens]                          29   2.9  
gi|7657265 fem-1 homolog b [Homo sapiens]                              28   4.9  
gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens]             28   6.4  
gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens]              28   6.4  
gi|21735598 programmed cell death 4 isoform 2 [Homo sapiens]           27   8.4  
gi|21735596 programmed cell death 4 isoform 1 [Homo sapiens]           27   8.4  
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho...    27   8.4  
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho...    27   8.4  
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho...    27   8.4  
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho...    27   8.4  

>gi|157384994 hypothetical protein LOC136157 [Homo sapiens]
          Length = 194

 Score =  400 bits (1027), Expect = e-112
 Identities = 194/194 (100%), Positives = 194/194 (100%)

Query: 1   MLSSPLRVAVVCVSNINRSMEAHSILRRKGLSVRSFGTESHVRLPGRRPNHPVVYDFATT 60
           MLSSPLRVAVVCVSNINRSMEAHSILRRKGLSVRSFGTESHVRLPGRRPNHPVVYDFATT
Sbjct: 1   MLSSPLRVAVVCVSNINRSMEAHSILRRKGLSVRSFGTESHVRLPGRRPNHPVVYDFATT 60

Query: 61  YKEMYNDLLRKDRECYTHNGILHILGRNERIKPGPERFQECTEFFDVIFTCEERVYDTVV 120
           YKEMYNDLLRKDRECYTHNGILHILGRNERIKPGPERFQECTEFFDVIFTCEERVYDTVV
Sbjct: 61  YKEMYNDLLRKDRECYTHNGILHILGRNERIKPGPERFQECTEFFDVIFTCEERVYDTVV 120

Query: 121 EDLCSREQQTFQPVHVINMDIKDTLEGAILGAFLICEICQCLQQSDDMEDSLEELLLQME 180
           EDLCSREQQTFQPVHVINMDIKDTLEGAILGAFLICEICQCLQQSDDMEDSLEELLLQME
Sbjct: 121 EDLCSREQQTFQPVHVINMDIKDTLEGAILGAFLICEICQCLQQSDDMEDSLEELLLQME 180

Query: 181 EKAGKSFLHTVCFY 194
           EKAGKSFLHTVCFY
Sbjct: 181 EKAGKSFLHTVCFY 194


>gi|7661832 Ssu72 RNA polymerase II CTD phosphatase homolog [Homo
           sapiens]
          Length = 194

 Score =  289 bits (739), Expect = 1e-78
 Identities = 136/194 (70%), Positives = 163/194 (84%)

Query: 1   MLSSPLRVAVVCVSNINRSMEAHSILRRKGLSVRSFGTESHVRLPGRRPNHPVVYDFATT 60
           M SSPLRVAVVC SN NRSMEAH+IL ++G SVRSFGT +HV+LPG  P+ P VYDF TT
Sbjct: 1   MPSSPLRVAVVCSSNQNRSMEAHNILSKRGFSVRSFGTGTHVKLPGPAPDKPNVYDFKTT 60

Query: 61  YKEMYNDLLRKDRECYTHNGILHILGRNERIKPGPERFQECTEFFDVIFTCEERVYDTVV 120
           Y +MYNDLLRKD+E YT NGILH+L RN+RIKP PERFQ C + FD+I TCEERVYD VV
Sbjct: 61  YDQMYNDLLRKDKELYTQNGILHMLDRNKRIKPRPERFQNCKDLFDLILTCEERVYDQVV 120

Query: 121 EDLCSREQQTFQPVHVINMDIKDTLEGAILGAFLICEICQCLQQSDDMEDSLEELLLQME 180
           EDL SREQ+T QPVHV+N+DI+D  E A LGAFLICE+CQC+Q ++DME+ ++ELL + E
Sbjct: 121 EDLNSREQETCQPVHVVNVDIQDNHEEATLGAFLICELCQCIQHTEDMENEIDELLQEFE 180

Query: 181 EKAGKSFLHTVCFY 194
           EK+G++FLHTVCFY
Sbjct: 181 EKSGRTFLHTVCFY 194


>gi|169217206 PREDICTED: similar to Ssu72 RNA polymerase II CTD
           phosphatase homolog [Homo sapiens]
          Length = 194

 Score =  268 bits (686), Expect = 2e-72
 Identities = 123/194 (63%), Positives = 158/194 (81%)

Query: 1   MLSSPLRVAVVCVSNINRSMEAHSILRRKGLSVRSFGTESHVRLPGRRPNHPVVYDFATT 60
           M  SPLRVAVVC +N N+SMEAH +L ++G SV+SFG   HV+LPG  PN P +YDF TT
Sbjct: 1   MSLSPLRVAVVCWNNQNQSMEAHRVLNKRGFSVQSFGITPHVKLPGPAPNKPNIYDFKTT 60

Query: 61  YKEMYNDLLRKDRECYTHNGILHILGRNERIKPGPERFQECTEFFDVIFTCEERVYDTVV 120
           Y EMYNDL+ KD E YT NG+L++L RN+RIK  PERFQ+C + FD+I TCEE +YD VV
Sbjct: 61  YDEMYNDLITKDEEFYTQNGVLYMLDRNKRIKLRPERFQDCKDVFDLIITCEESIYDQVV 120

Query: 121 EDLCSREQQTFQPVHVINMDIKDTLEGAILGAFLICEICQCLQQSDDMEDSLEELLLQME 180
           EDL SREQ+T +PVHV+NMDI+D  E AI+GAFLICE+CQC+Q+S+DME+ +++LL ++E
Sbjct: 121 EDLNSREQETCRPVHVVNMDIQDNQEDAIIGAFLICELCQCIQRSEDMENEIDQLLQKLE 180

Query: 181 EKAGKSFLHTVCFY 194
           +K G++FLHTVCFY
Sbjct: 181 KKRGQAFLHTVCFY 194


>gi|89060983 PREDICTED: similar to Ssu72 RNA polymerase II CTD
           phosphatase homolog [Homo sapiens]
          Length = 194

 Score =  268 bits (686), Expect = 2e-72
 Identities = 123/194 (63%), Positives = 158/194 (81%)

Query: 1   MLSSPLRVAVVCVSNINRSMEAHSILRRKGLSVRSFGTESHVRLPGRRPNHPVVYDFATT 60
           M  SPLRVAVVC +N N+SMEAH +L ++G SV+SFG   HV+LPG  PN P +YDF TT
Sbjct: 1   MSLSPLRVAVVCWNNQNQSMEAHRVLNKRGFSVQSFGITPHVKLPGPAPNKPNIYDFKTT 60

Query: 61  YKEMYNDLLRKDRECYTHNGILHILGRNERIKPGPERFQECTEFFDVIFTCEERVYDTVV 120
           Y EMYNDL+ KD E YT NG+L++L RN+RIK  PERFQ+C + FD+I TCEE +YD VV
Sbjct: 61  YDEMYNDLITKDEEFYTQNGVLYMLDRNKRIKLRPERFQDCKDVFDLIITCEESIYDQVV 120

Query: 121 EDLCSREQQTFQPVHVINMDIKDTLEGAILGAFLICEICQCLQQSDDMEDSLEELLLQME 180
           EDL SREQ+T +PVHV+NMDI+D  E AI+GAFLICE+CQC+Q+S+DME+ +++LL ++E
Sbjct: 121 EDLNSREQETCRPVHVVNMDIQDNQEDAIIGAFLICELCQCIQRSEDMENEIDQLLQKLE 180

Query: 181 EKAGKSFLHTVCFY 194
           +K G++FLHTVCFY
Sbjct: 181 KKRGQAFLHTVCFY 194


>gi|27486601 PREDICTED: similar to Ssu72 RNA polymerase II CTD
           phosphatase homolog [Homo sapiens]
          Length = 194

 Score =  268 bits (686), Expect = 2e-72
 Identities = 123/194 (63%), Positives = 158/194 (81%)

Query: 1   MLSSPLRVAVVCVSNINRSMEAHSILRRKGLSVRSFGTESHVRLPGRRPNHPVVYDFATT 60
           M  SPLRVAVVC +N N+SMEAH +L ++G SV+SFG   HV+LPG  PN P +YDF TT
Sbjct: 1   MSLSPLRVAVVCWNNQNQSMEAHRVLNKRGFSVQSFGITPHVKLPGPAPNKPNIYDFKTT 60

Query: 61  YKEMYNDLLRKDRECYTHNGILHILGRNERIKPGPERFQECTEFFDVIFTCEERVYDTVV 120
           Y EMYNDL+ KD E YT NG+L++L RN+RIK  PERFQ+C + FD+I TCEE +YD VV
Sbjct: 61  YDEMYNDLITKDEEFYTQNGVLYMLDRNKRIKLRPERFQDCKDVFDLIITCEESIYDQVV 120

Query: 121 EDLCSREQQTFQPVHVINMDIKDTLEGAILGAFLICEICQCLQQSDDMEDSLEELLLQME 180
           EDL SREQ+T +PVHV+NMDI+D  E AI+GAFLICE+CQC+Q+S+DME+ +++LL ++E
Sbjct: 121 EDLNSREQETCRPVHVVNMDIQDNQEDAIIGAFLICELCQCIQRSEDMENEIDQLLQKLE 180

Query: 181 EKAGKSFLHTVCFY 194
           +K G++FLHTVCFY
Sbjct: 181 KKRGQAFLHTVCFY 194


>gi|54859722 nucleoporin 160kDa [Homo sapiens]
          Length = 1436

 Score = 28.9 bits (63), Expect = 2.9
 Identities = 10/27 (37%), Positives = 19/27 (70%)

Query: 117 DTVVEDLCSREQQTFQPVHVINMDIKD 143
           + V+ED+CS+ Q+   P+H I + I++
Sbjct: 652 ENVMEDICSKLQEIRNPIHAIGLLIRE 678


>gi|7657265 fem-1 homolog b [Homo sapiens]
          Length = 627

 Score = 28.1 bits (61), Expect = 4.9
 Identities = 24/106 (22%), Positives = 40/106 (37%), Gaps = 10/106 (9%)

Query: 41  HVRLPGRRPNHPVVYDFATTYKEM--YNDLLR-KDRECYTHNGILHILGRNERIKPGPER 97
           H+R  G R  H  +  FA  + +M   N+ ++  D EC     +L I     R+K   + 
Sbjct: 372 HLRQKGNRNTHKDLLRFAQVFSQMIHLNETVKAPDIECVLRCSVLEIEQSMNRVKNISDA 431

Query: 98  -------FQECTEFFDVIFTCEERVYDTVVEDLCSREQQTFQPVHV 136
                    EC  +  +   C         ED C   +Q +  +H+
Sbjct: 432 DVHNAMDNYECNLYTFLYLVCISTKTQCSEEDQCKINKQIYNLIHL 477


>gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens]
          Length = 963

 Score = 27.7 bits (60), Expect = 6.4
 Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 14/93 (15%)

Query: 27  RRKGL----SVRSFGTESHVRLPGRRPNHP-VVYDFATTYKEMYNDLLRKDRECYT-HNG 80
           RRK L    +V S GT      P      P +  D+    K+ Y D +  + E Y  H+ 
Sbjct: 712 RRKQLFTLQTVNSNGTSDRTTSPEEVHAQPYIAIDWEPEMKKRYYDEV--EAEGYVKHDC 769

Query: 81  ILHILGRNERIKPGPERFQECTEFFDVIFTCEE 113
           + +++      K  P R QEC E F  + T E+
Sbjct: 770 VGYVM------KKAPVRLQECIELFTTVETLEK 796


>gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens]
          Length = 953

 Score = 27.7 bits (60), Expect = 6.4
 Identities = 30/111 (27%), Positives = 44/111 (39%), Gaps = 5/111 (4%)

Query: 82  LHILGRNERIKPGPERFQECTEFFDV-IFTCEER---VYDTVVEDLCSREQQTFQPVHVI 137
           LH  G  +     P+    C     V  F  E R   VY    + +C+   +  Q   ++
Sbjct: 565 LHTQGVLDTAALPPDPSSTCKRQLGVGAFPVESRWQGVYSPFRDFVCAGCPRDLQEA-LL 623

Query: 138 NMDIKDTLEGAILGAFLICEICQCLQQSDDMEDSLEELLLQMEEKAGKSFL 188
             D++ + E      +L CE          MED LEELL   E KA + +L
Sbjct: 624 GFDVQSSRELRRSQDYLSCERTHPEDSVGSMEDILEELLQHREPKALQLYL 674


>gi|21735598 programmed cell death 4 isoform 2 [Homo sapiens]
          Length = 458

 Score = 27.3 bits (59), Expect = 8.4
 Identities = 14/65 (21%), Positives = 34/65 (52%)

Query: 119 VVEDLCSREQQTFQPVHVINMDIKDTLEGAILGAFLICEICQCLQQSDDMEDSLEELLLQ 178
           ++ DL   E ++  PV  +++ ++       + + L+ ++C  +  + D+E S ++LL  
Sbjct: 176 MLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTTDVEKSFDKLLKD 235

Query: 179 MEEKA 183
           + E A
Sbjct: 236 LPELA 240


>gi|21735596 programmed cell death 4 isoform 1 [Homo sapiens]
          Length = 469

 Score = 27.3 bits (59), Expect = 8.4
 Identities = 14/65 (21%), Positives = 34/65 (52%)

Query: 119 VVEDLCSREQQTFQPVHVINMDIKDTLEGAILGAFLICEICQCLQQSDDMEDSLEELLLQ 178
           ++ DL   E ++  PV  +++ ++       + + L+ ++C  +  + D+E S ++LL  
Sbjct: 187 MLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTTDVEKSFDKLLKD 246

Query: 179 MEEKA 183
           + E A
Sbjct: 247 LPELA 251


>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
           sapiens]
          Length = 638

 Score = 27.3 bits (59), Expect = 8.4
 Identities = 22/100 (22%), Positives = 45/100 (45%), Gaps = 19/100 (19%)

Query: 84  ILGRNERIKPGPERFQECTEFFDVIFTCEERVYDTVVEDLCSREQQTFQPVHVINMDIKD 143
           IL + ER     E+ Q+     D +   E+ +  ++ + LCS +++  +  ++   ++K 
Sbjct: 240 ILEQQER-----EKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQ 294

Query: 144 TLEGAILGAFLICEICQCLQQSDDMEDSLEELLLQMEEKA 183
           TL+               L +    E+  E L+ Q+EE+A
Sbjct: 295 TLDE--------------LDKLQQKEEQAERLVKQLEEEA 320


>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
           sapiens]
          Length = 725

 Score = 27.3 bits (59), Expect = 8.4
 Identities = 22/100 (22%), Positives = 45/100 (45%), Gaps = 19/100 (19%)

Query: 84  ILGRNERIKPGPERFQECTEFFDVIFTCEERVYDTVVEDLCSREQQTFQPVHVINMDIKD 143
           IL + ER     E+ Q+     D +   E+ +  ++ + LCS +++  +  ++   ++K 
Sbjct: 327 ILEQQER-----EKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQ 381

Query: 144 TLEGAILGAFLICEICQCLQQSDDMEDSLEELLLQMEEKA 183
           TL+               L +    E+  E L+ Q+EE+A
Sbjct: 382 TLDE--------------LDKLQQKEEQAERLVKQLEEEA 407


>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
           sapiens]
          Length = 709

 Score = 27.3 bits (59), Expect = 8.4
 Identities = 22/100 (22%), Positives = 45/100 (45%), Gaps = 19/100 (19%)

Query: 84  ILGRNERIKPGPERFQECTEFFDVIFTCEERVYDTVVEDLCSREQQTFQPVHVINMDIKD 143
           IL + ER     E+ Q+     D +   E+ +  ++ + LCS +++  +  ++   ++K 
Sbjct: 311 ILEQQER-----EKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQ 365

Query: 144 TLEGAILGAFLICEICQCLQQSDDMEDSLEELLLQMEEKA 183
           TL+               L +    E+  E L+ Q+EE+A
Sbjct: 366 TLDE--------------LDKLQQKEEQAERLVKQLEEEA 391


>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
           sapiens]
          Length = 724

 Score = 27.3 bits (59), Expect = 8.4
 Identities = 22/100 (22%), Positives = 45/100 (45%), Gaps = 19/100 (19%)

Query: 84  ILGRNERIKPGPERFQECTEFFDVIFTCEERVYDTVVEDLCSREQQTFQPVHVINMDIKD 143
           IL + ER     E+ Q+     D +   E+ +  ++ + LCS +++  +  ++   ++K 
Sbjct: 326 ILEQQER-----EKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQ 380

Query: 144 TLEGAILGAFLICEICQCLQQSDDMEDSLEELLLQMEEKA 183
           TL+               L +    E+  E L+ Q+EE+A
Sbjct: 381 TLDE--------------LDKLQQKEEQAERLVKQLEEEA 406


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.139    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,848,065
Number of Sequences: 37866
Number of extensions: 336218
Number of successful extensions: 1019
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1011
Number of HSP's gapped (non-prelim): 15
length of query: 194
length of database: 18,247,518
effective HSP length: 97
effective length of query: 97
effective length of database: 14,574,516
effective search space: 1413728052
effective search space used: 1413728052
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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