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Search of human proteins with 156713448
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156713448 selenocysteine lyase [Homo sapiens]
(445 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156713448 selenocysteine lyase [Homo sapiens] 892 0.0
gi|32307132 NFS1 nitrogen fixation 1 [Homo sapiens] 213 3e-55
gi|8922854 kelch-like 26 [Homo sapiens] 32 1.5
gi|158634482 poly (ADP-ribose) polymerase family, member 3 isofo... 30 3.4
gi|158634478 poly (ADP-ribose) polymerase family, member 3 isofo... 30 3.4
gi|239753475 PREDICTED: hypothetical protein [Homo sapiens] 30 4.4
gi|239748044 PREDICTED: hypothetical protein XP_002346500 [Homo ... 30 4.4
gi|239741935 PREDICTED: hypothetical protein XP_002342357 [Homo ... 30 4.4
gi|38569417 alanyl-tRNA synthetase 2, mitochondrial [Homo sapiens] 30 4.4
gi|163965366 nascent polypeptide-associated complex alpha subuni... 30 5.8
gi|118600967 shroom family member 4 [Homo sapiens] 29 7.5
gi|10047144 sal-like 4 [Homo sapiens] 29 7.5
gi|94966757 protein disulfide isomerase A2 [Homo sapiens] 29 7.5
gi|239752280 PREDICTED: similar to family with sequence similari... 29 9.9
gi|87196343 PDZ domain containing 2 [Homo sapiens] 29 9.9
gi|210032463 family with sequence similarity 48, member B2 [Homo... 29 9.9
>gi|156713448 selenocysteine lyase [Homo sapiens]
Length = 445
Score = 892 bits (2304), Expect = 0.0
Identities = 445/445 (100%), Positives = 445/445 (100%)
Query: 1 MEAAVAPGRDAPAPAASQPSGCGKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGN 60
MEAAVAPGRDAPAPAASQPSGCGKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGN
Sbjct: 1 MEAAVAPGRDAPAPAASQPSGCGKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGN 60
Query: 61 PSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTS 120
PSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTS
Sbjct: 61 PSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTS 120
Query: 121 KGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDI 180
KGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDI
Sbjct: 121 KGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDI 180
Query: 181 LAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGK 240
LAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGK
Sbjct: 181 LAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGK 240
Query: 241 QRVDVEDLGVDFLTIVGHKFYGPRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTP 300
QRVDVEDLGVDFLTIVGHKFYGPRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTP
Sbjct: 241 QRVDVEDLGVDFLTIVGHKFYGPRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTP 300
Query: 301 MIAGLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCN 360
MIAGLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCN
Sbjct: 301 MIAGLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCN 360
Query: 361 FSIRGPRLQGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGR 420
FSIRGPRLQGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGR
Sbjct: 361 FSIRGPRLQGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGR 420
Query: 421 STTRAEVDLVVQDLKQAVAQLEDQA 445
STTRAEVDLVVQDLKQAVAQLEDQA
Sbjct: 421 STTRAEVDLVVQDLKQAVAQLEDQA 445
>gi|32307132 NFS1 nitrogen fixation 1 [Homo sapiens]
Length = 457
Score = 213 bits (542), Expect = 3e-55
Identities = 151/442 (34%), Positives = 227/442 (51%), Gaps = 43/442 (9%)
Query: 6 APGRDAPAPAASQPSGCGKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSS-P 64
AP PA A+ P + R +YMD ATTPL+P V+ AM + +GNP S
Sbjct: 37 APQSAVPADTAAAP----EVGPVLRPLYMDVQATTPLDPRVLDAMLPYLINYYGNPHSRT 92
Query: 65 YSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHT 124
++ G +++ + AR+ +A +IG P++IIFTSG TESNN+ I V + + +
Sbjct: 93 HAYGWESEAAMERARQQVASLIGADPREIIFTSGATESNNIAIKGVARFYRSR------- 145
Query: 125 GGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAV 184
K H IT+ EH + L +E + VT++PV K SG ++ ++ AA+
Sbjct: 146 ----------KKHLITTQTEHKCV-LDSCRSLEAEGFQVTYLPVQK-SGIIDLKELEAAI 193
Query: 185 RPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVD 244
+P T LV++M NNE G+ P+ EI + + + HTDAAQA+GK +D
Sbjct: 194 QPDTSLVSVMTVNNEIGVKQPIAEIGRICSSRK----------VYFHTDAAQAVGKIPLD 243
Query: 245 VEDLGVDFLTIVGHKFYGPR-IGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIA 303
V D+ +D ++I GHK YGP+ +GA+YIR + + GGGQER R GT TP++
Sbjct: 244 VNDMKIDLMSISGHKIYGPKGVGAIYIRRRPR-VRVEALQSGGGQERGMRSGTVPTPLVV 302
Query: 304 GLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSI 363
GLG A E+ Q E Y+ H R + L ERL + + P N S
Sbjct: 303 GLGAACEVAQQEME-YD-HKRISK--LSERLIQNIMKSLPDVVMNGDPKHHYPGCINLSF 358
Query: 364 RGPRLQGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTT 423
++G +L + + S G+AC S +PS VL + G D+A +++R +GR TT
Sbjct: 359 --AYVEGESLLMALKDVALSSGSACTS-ASLEPSYVLRAIGTDEDLAHSSIRFGIGRFTT 415
Query: 424 RAEVDLVVQDLKQAVAQLEDQA 445
EVD V+ Q V +L + +
Sbjct: 416 EEEVDYTVEKCIQHVKRLREMS 437
>gi|8922854 kelch-like 26 [Homo sapiens]
Length = 615
Score = 31.6 bits (70), Expect = 1.5
Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 7/49 (14%)
Query: 137 HFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVR 185
HF+ + E D +RLPLE L V F+ +++ AE+D AAVR
Sbjct: 191 HFLQIAEEEDFLRLPLERL-------VFFLQSNRLQSCAEIDLFRAAVR 232
>gi|158634482 poly (ADP-ribose) polymerase family, member 3 isoform
b [Homo sapiens]
Length = 533
Score = 30.4 bits (67), Expect = 3.4
Identities = 26/129 (20%), Positives = 56/129 (43%), Gaps = 6/129 (4%)
Query: 135 KPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIM 194
+ HF++ ++ I + E +E V V PV V+ + + + A T +L+T +
Sbjct: 140 RDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVTKRVQPCSLDPA---TQKLITNI 196
Query: 195 LANN---ETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVD 251
+ T +M + + L+++++A G + +A + +E+L
Sbjct: 197 FSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSH 256
Query: 252 FLTIVGHKF 260
F T++ H F
Sbjct: 257 FYTVIPHNF 265
>gi|158634478 poly (ADP-ribose) polymerase family, member 3 isoform
a [Homo sapiens]
Length = 540
Score = 30.4 bits (67), Expect = 3.4
Identities = 26/129 (20%), Positives = 56/129 (43%), Gaps = 6/129 (4%)
Query: 135 KPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIM 194
+ HF++ ++ I + E +E V V PV V+ + + + A T +L+T +
Sbjct: 147 RDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVTKRVQPCSLDPA---TQKLITNI 203
Query: 195 LANN---ETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVD 251
+ T +M + + L+++++A G + +A + +E+L
Sbjct: 204 FSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSH 263
Query: 252 FLTIVGHKF 260
F T++ H F
Sbjct: 264 FYTVIPHNF 272
>gi|239753475 PREDICTED: hypothetical protein [Homo sapiens]
Length = 721
Score = 30.0 bits (66), Expect = 4.4
Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 16/119 (13%)
Query: 120 SKGHTGGHHSPV-------KGAKPHFITSSVEHDSIR--LPLEHLV-EEQVAAVTFVPVS 169
S GH HS + + P+ +S+++ +R L E+L EE AA +
Sbjct: 14 STGHLPSQHSSYGAQNKNKRPSVPYLNSSALQRVDVRWFLLCENLQREEPTAACVHLCAQ 73
Query: 170 KVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPI 228
G V +AA+ TI L+ MP + S R+KA + A LPP+
Sbjct: 74 APDGLLGVQSAVAALTSHRTTCTISLSE------MPGQDSSARLKAFSSSSSAPTLPPL 126
>gi|239748044 PREDICTED: hypothetical protein XP_002346500 [Homo
sapiens]
Length = 721
Score = 30.0 bits (66), Expect = 4.4
Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 16/119 (13%)
Query: 120 SKGHTGGHHSPV-------KGAKPHFITSSVEHDSIR--LPLEHLV-EEQVAAVTFVPVS 169
S GH HS + + P+ +S+++ +R L E+L EE AA +
Sbjct: 14 STGHLPSQHSSYGAQNKNKRPSVPYLNSSALQRVDVRWFLLCENLQREEPTAACVHLCAQ 73
Query: 170 KVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPI 228
G V +AA+ TI L+ MP + S R+KA + A LPP+
Sbjct: 74 APDGLLGVQSAVAALTSHRTTCTISLSE------MPGQDSSARLKAFSSSSSAPTLPPL 126
>gi|239741935 PREDICTED: hypothetical protein XP_002342357 [Homo
sapiens]
Length = 721
Score = 30.0 bits (66), Expect = 4.4
Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 16/119 (13%)
Query: 120 SKGHTGGHHSPV-------KGAKPHFITSSVEHDSIR--LPLEHLV-EEQVAAVTFVPVS 169
S GH HS + + P+ +S+++ +R L E+L EE AA +
Sbjct: 14 STGHLPSQHSSYGAQNKNKRPSVPYLNSSALQRVDVRWFLLCENLQREEPTAACVHLCAQ 73
Query: 170 KVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPI 228
G V +AA+ TI L+ MP + S R+KA + A LPP+
Sbjct: 74 APDGLLGVQSAVAALTSHRTTCTISLSE------MPGQDSSARLKAFSSSSSAPTLPPL 126
>gi|38569417 alanyl-tRNA synthetase 2, mitochondrial [Homo sapiens]
Length = 985
Score = 30.0 bits (66), Expect = 4.4
Identities = 15/43 (34%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 23 GKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPY 65
G H +PE+ + +D TPL PE ++A+ + EA G + Y
Sbjct: 654 GSHLNPEQ-LRLDVTTQTPLTPEQLRAVENTVQEAVGQDEAVY 695
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 29.6 bits (65), Expect = 5.8
Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 4 AVAPGRDAPAP-AASQPSGCGKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPS 62
A +P + AP P AA+ PS G +P K A TP P+ + + G P+
Sbjct: 1302 ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361
Query: 63 SPYS 66
+P S
Sbjct: 1362 TPSS 1365
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 29.3 bits (64), Expect = 7.5
Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 9/103 (8%)
Query: 46 VIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTES-NN 104
++QA TKA+ G+P + A + +N A LAK G+P +I +G S
Sbjct: 359 LMQASTKAV----GSPKACDRASSVDSNPLNEASAELAKASFGRPPHLIGPTGHRHSAPE 414
Query: 105 LVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDS 147
++ S ++H H + ++G G PV+ H T S H S
Sbjct: 415 QLLASHLQHVHLD--TRGSKGMELPPVQDG--HQWTLSPLHSS 453
>gi|10047144 sal-like 4 [Homo sapiens]
Length = 1053
Score = 29.3 bits (64), Expect = 7.5
Identities = 16/50 (32%), Positives = 20/50 (40%), Gaps = 9/50 (18%)
Query: 342 RIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMASVGAACHSD 391
R+H+ Q P T N C+F+ P G S GA CH D
Sbjct: 646 RMHMGGQIPNTPLPENPCDFTGSEPMTVGE---------NGSTGAICHDD 686
>gi|94966757 protein disulfide isomerase A2 [Homo sapiens]
Length = 525
Score = 29.3 bits (64), Expect = 7.5
Identities = 16/50 (32%), Positives = 25/50 (50%)
Query: 379 VLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVD 428
V AS+ A CH+ Q P LLS +P D + ++ VG++ + D
Sbjct: 355 VTAASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVAFD 404
>gi|239752280 PREDICTED: similar to family with sequence similarity
48, member B2 [Homo sapiens]
Length = 779
Score = 28.9 bits (63), Expect = 9.9
Identities = 47/231 (20%), Positives = 84/231 (36%), Gaps = 21/231 (9%)
Query: 6 APGRDAPAPAASQPSGCGKHNSP---ERKVYMDYNATTPLE-----PEVIQAMTKAMWEA 57
APG APAPA SG P R + ++ PL+ PE ++ +T + +
Sbjct: 559 APGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQG 618
Query: 58 WGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHAN 117
W + P + + + + A PQ G + + L + + + F A
Sbjct: 619 WAVLTGPQQQSHQLVSLQQLQQPTAAH----PPQP------GPQGSTLGLSTQGQAFPAQ 668
Query: 118 QTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEV 177
Q + G S ++ + S + S ++P + + V P+ + Q +
Sbjct: 669 QLLNVNLTGAGSGLQPQPQAAVLSLL--GSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQP 726
Query: 178 DDILAAVRPTTRL-VTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPP 227
I +P L + LA IV P P + + + Q + PP
Sbjct: 727 QQIQLQTQPLRVLQQPVFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPP 777
>gi|87196343 PDZ domain containing 2 [Homo sapiens]
Length = 2839
Score = 28.9 bits (63), Expect = 9.9
Identities = 17/65 (26%), Positives = 29/65 (44%)
Query: 2 EAAVAPGRDAPAPAASQPSGCGKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNP 61
+AA PG P +SQPS + +S E + + D + + P + T+ +
Sbjct: 1648 KAACLPGSYTSGPDSSQPSSLLEMSSQEHETHADISTSQNHRPSCAEETTEVTSASSAME 1707
Query: 62 SSPYS 66
+SP S
Sbjct: 1708 NSPLS 1712
>gi|210032463 family with sequence similarity 48, member B2 [Homo
sapiens]
Length = 817
Score = 28.9 bits (63), Expect = 9.9
Identities = 47/231 (20%), Positives = 84/231 (36%), Gaps = 21/231 (9%)
Query: 6 APGRDAPAPAASQPSGCGKHNSP---ERKVYMDYNATTPLE-----PEVIQAMTKAMWEA 57
APG APAPA SG P R + ++ PL+ PE ++ +T + +
Sbjct: 597 APGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQG 656
Query: 58 WGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHAN 117
W + P + + + + A PQ G + + L + + + F A
Sbjct: 657 WAVLTGPQQQSHQLVSLQQLQQPTAAH----PPQP------GPQGSTLGLSTQGQAFPAQ 706
Query: 118 QTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEV 177
Q + G S ++ + S + S ++P + + V P+ + Q +
Sbjct: 707 QLLNVNLTGAGSGLQPQPQAAVLSLL--GSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQP 764
Query: 178 DDILAAVRPTTRL-VTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPP 227
I +P L + LA IV P P + + + Q + PP
Sbjct: 765 QQIQLQTQPLRVLQQPVFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPP 815
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,547,149
Number of Sequences: 37866
Number of extensions: 816936
Number of successful extensions: 2128
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2111
Number of HSP's gapped (non-prelim): 24
length of query: 445
length of database: 18,247,518
effective HSP length: 105
effective length of query: 340
effective length of database: 14,271,588
effective search space: 4852339920
effective search space used: 4852339920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.