Guide to the Human Genome
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Search of human proteins with 11034819

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11034819 nuclear receptor interacting protein 3 [Homo
sapiens]
         (241 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11034819 nuclear receptor interacting protein 3 [Homo sapiens]     478   e-135
gi|13899327 nuclear receptor interacting protein 2 [Homo sapiens]     149   2e-36
gi|48717485 DDI1, DNA-damage inducible 1, homolog 1 [Homo sapiens]     58   6e-09
gi|62955833 DNA-damage inducible protein 2 [Homo sapiens]              54   2e-07
gi|115387118 hypothetical protein LOC57562 [Homo sapiens]              31   1.1  
gi|38788380 dehydrogenase E1 and transketolase domain containing...    30   1.9  
gi|81295809 pericentrin [Homo sapiens]                                 29   3.2  
gi|45827729 scribble isoform b [Homo sapiens]                          29   3.2  
gi|45827731 scribble isoform a [Homo sapiens]                          29   3.2  
gi|153792633 hypothetical protein LOC26049 [Homo sapiens]              28   5.5  
gi|33946327 nucleoporin 214kDa [Homo sapiens]                          28   7.1  
gi|13569922 NUAK family, SNF1-like kinase, 2 [Homo sapiens]            28   9.3  

>gi|11034819 nuclear receptor interacting protein 3 [Homo sapiens]
          Length = 241

 Score =  478 bits (1230), Expect = e-135
 Identities = 241/241 (100%), Positives = 241/241 (100%)

Query: 1   MFYSGLLTEGGRKETDMREAASLRQQRRMKQAVQFIHKDSADLLPLDGLKKLGSSKDMQP 60
           MFYSGLLTEGGRKETDMREAASLRQQRRMKQAVQFIHKDSADLLPLDGLKKLGSSKDMQP
Sbjct: 1   MFYSGLLTEGGRKETDMREAASLRQQRRMKQAVQFIHKDSADLLPLDGLKKLGSSKDMQP 60

Query: 61  HNILQRRLMETNLSKLRSGPRVPWASKTNKLNQAKSEGLKKSEEDDMILVSCQCAGKDVK 120
           HNILQRRLMETNLSKLRSGPRVPWASKTNKLNQAKSEGLKKSEEDDMILVSCQCAGKDVK
Sbjct: 61  HNILQRRLMETNLSKLRSGPRVPWASKTNKLNQAKSEGLKKSEEDDMILVSCQCAGKDVK 120

Query: 121 ALVDTGCLYNLISLACVDRLGLKEHVKSHKHEGEKLSLPRHLKVVGQIEHLVITLGSLRL 180
           ALVDTGCLYNLISLACVDRLGLKEHVKSHKHEGEKLSLPRHLKVVGQIEHLVITLGSLRL
Sbjct: 121 ALVDTGCLYNLISLACVDRLGLKEHVKSHKHEGEKLSLPRHLKVVGQIEHLVITLGSLRL 180

Query: 181 DCPAAVVDDNEKNLSLGLQTLRSLKCIINLDKHRLIMGKTDKEEIPFVETVSLNEDNTSE 240
           DCPAAVVDDNEKNLSLGLQTLRSLKCIINLDKHRLIMGKTDKEEIPFVETVSLNEDNTSE
Sbjct: 181 DCPAAVVDDNEKNLSLGLQTLRSLKCIINLDKHRLIMGKTDKEEIPFVETVSLNEDNTSE 240

Query: 241 A 241
           A
Sbjct: 241 A 241


>gi|13899327 nuclear receptor interacting protein 2 [Homo sapiens]
          Length = 281

 Score =  149 bits (377), Expect = 2e-36
 Identities = 90/216 (41%), Positives = 127/216 (58%), Gaps = 11/216 (5%)

Query: 13  KETDMREAASLRQQRRMKQAVQFIHKDSADLLPLDGLKKLGSSKDMQPHNILQRRLMETN 72
           +E  +R+ A L QQRR+KQA QF+HKDSADLLPLD LK+LG+SKD+QP +++QRRL+E N
Sbjct: 69  QEAQLRDRAHLSQQRRLKQATQFLHKDSADLLPLDSLKRLGTSKDLQPRSVIQRRLVEGN 128

Query: 73  LSKLRSGPRVPWASKTNKLNQAKSEGLKKSEEDDMILVSCQCAGKDVKALVDTGCLYNLI 132
            + L+  P        + ++  +S       E   +LV+C+C  + ++  VDTG  YN I
Sbjct: 129 PNWLQGEP----PRMQDLIHGQESRRKTSRTEIPALLVNCKCQDQLLRVAVDTGTQYNRI 184

Query: 133 SLACVDRLGLKEHVKSHKHEGEKLSLPRHLKVVGQIEHLVITLGSLRLDCPAAVVDDNEK 192
           S  C+ RLGL++ V      G+    P       Q+E L + LG   + C A VVD    
Sbjct: 185 SAGCLSRLGLEKRVLK-ASAGDLAPGP-----PTQVEQLELQLGQETVVCSAQVVDAESP 238

Query: 193 NLSLGLQTLRSLKCIINLDKHRLIMGKTDKEEIPFV 228
              LGLQTL SLKC I+L+ H ++  K    E+PF+
Sbjct: 239 EFCLGLQTLLSLKCCIDLE-HGVLRLKAPFSELPFL 273


>gi|48717485 DDI1, DNA-damage inducible 1, homolog 1 [Homo sapiens]
          Length = 396

 Score = 58.2 bits (139), Expect = 6e-09
 Identities = 38/157 (24%), Positives = 76/157 (48%), Gaps = 9/157 (5%)

Query: 91  LNQAKSEGLKKSEEDDMILVSCQCAGKDVKALVDTGCLYNLISLACVDRLGLKEHVKSHK 150
           +N A  E  +   +  M+ ++C+  G  +KA VD+G    ++S AC +R  +   V   +
Sbjct: 227 MNIAIEEAPESFGQVTMLYINCKVNGHPLKAFVDSGAQMTIMSQACAERCNIMRLV-DRR 285

Query: 151 HEGEKLSLPRHLKVVGQIEHLVITLGSLRLDCPAAVVDDNEKNLSLGLQTLRSLKCIINL 210
             G    +    +++G++    I +    L C  ++++D   ++ LGL  LR  +C I+L
Sbjct: 286 WAGVAKGVGTQ-RIIGRVHLAQIQIEGDFLQCSFSILEDQPMDMLLGLDMLRRHQCSIDL 344

Query: 211 DKHRLIMGKTDKE-------EIPFVETVSLNEDNTSE 240
            K+ L++G T  +       E+P    +   +D +S+
Sbjct: 345 KKNVLVIGTTGTQTYFLPEGELPLCSRMVSGQDESSD 381


>gi|62955833 DNA-damage inducible protein 2 [Homo sapiens]
          Length = 399

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 30/117 (25%), Positives = 61/117 (52%), Gaps = 2/117 (1%)

Query: 107 MILVSCQCAGKDVKALVDTGCLYNLISLACVDRLGLKEHVKSHKHEGEKLSLPRHLKVVG 166
           M+ ++C+  G  VKA VD+G    ++S AC +R  +   V   +  G    +    K++G
Sbjct: 235 MLYINCKVNGHPVKAFVDSGAQMTIMSQACAERCNIMRLV-DRRWAGIAKGVGTQ-KIIG 292

Query: 167 QIEHLVITLGSLRLDCPAAVVDDNEKNLSLGLQTLRSLKCIINLDKHRLIMGKTDKE 223
           ++    + +    L C  +++++   ++ LGL  L+  +C I+L K+ L++G T  +
Sbjct: 293 RVHLAQVQIEGDFLPCSFSILEEQPMDMLLGLDMLKRHQCSIDLKKNVLVIGTTGSQ 349


>gi|115387118 hypothetical protein LOC57562 [Homo sapiens]
          Length = 1117

 Score = 30.8 bits (68), Expect = 1.1
 Identities = 34/174 (19%), Positives = 76/174 (43%), Gaps = 8/174 (4%)

Query: 9   EGGRKETDMREAASLRQ--QRRMKQAVQFIHKDSADLLPLDGLKKLGSSKDMQPHNILQR 66
           E  RKE + +E     Q  Q+R ++  +   K     +PL   +K  S K + P     +
Sbjct: 86  EEKRKEQEEKEHQIREQILQQRKQKFEEVTEKFQRAHVPLSQRRKAVSRKPVPPLEEALK 145

Query: 67  RLMETNLSK-----LRSGPRVPWASKTNKLNQAKSEGLKKSEEDDMILVSCQC-AGKDVK 120
           ++ E+NL           P + W +  + L  A S+   K ++  +  ++C+    ++++
Sbjct: 146 QIQESNLKSEVNLPFSRRPTINWRAIDSALPSALSKNDHKHQKQLLSKINCEKEMNENMR 205

Query: 121 ALVDTGCLYNLISLACVDRLGLKEHVKSHKHEGEKLSLPRHLKVVGQIEHLVIT 174
           A + T      + L    +L   +H+ + +  G++++   + + +  I+ L  T
Sbjct: 206 ATLATSKNVFQLKLEETQKLLEDQHLSNLQKFGDEVNQITNSETLSSIDSLEAT 259


>gi|38788380 dehydrogenase E1 and transketolase domain containing 1
           [Homo sapiens]
          Length = 919

 Score = 30.0 bits (66), Expect = 1.9
 Identities = 12/45 (26%), Positives = 27/45 (60%)

Query: 42  DLLPLDGLKKLGSSKDMQPHNILQRRLMETNLSKLRSGPRVPWAS 86
           DLL   G+K +   +++Q H+ L +  +++ + K+  G ++ WA+
Sbjct: 529 DLLRFVGMKSVEVPRELQMHSHLLKTHVQSRMEKMMDGIKLDWAT 573


>gi|81295809 pericentrin [Homo sapiens]
          Length = 3336

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 12/106 (11%)

Query: 63  ILQRRLMETNLSKLRSGPRVPWASKTNKLN---QAKSEGLKKSEEDDMILVSCQCAGKDV 119
           +L R     +L +L+   +    S+  +L    + K    +K+ ++D+ L+  +  G   
Sbjct: 491 LLARTSRVEDLEQLKQREKTQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQRLQGARE 550

Query: 120 KALVDTGCLYNLISLACVD-----RLGLKEHVKSHKHEGEKLSLPR 160
            AL+D+      + L+CV        G K+HV   + E  K SLPR
Sbjct: 551 DALLDSV----EVGLSCVGLEEKPEKGRKDHVDELEPERHKESLPR 592


>gi|45827729 scribble isoform b [Homo sapiens]
          Length = 1630

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 10/29 (34%), Positives = 17/29 (58%)

Query: 78  SGPRVPWASKTNKLNQAKSEGLKKSEEDD 106
           +GP  PWA +  K  + + EG  + EE++
Sbjct: 647 NGPHAPWAPRAQKEEEEEEEGSPQEEEEE 675


>gi|45827731 scribble isoform a [Homo sapiens]
          Length = 1655

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 10/29 (34%), Positives = 17/29 (58%)

Query: 78  SGPRVPWASKTNKLNQAKSEGLKKSEEDD 106
           +GP  PWA +  K  + + EG  + EE++
Sbjct: 647 NGPHAPWAPRAQKEEEEEEEGSPQEEEEE 675


>gi|153792633 hypothetical protein LOC26049 [Homo sapiens]
          Length = 670

 Score = 28.5 bits (62), Expect = 5.5
 Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 7/74 (9%)

Query: 82  VPWASKTNKLNQAKSEGLKKSEEDDMILVSCQCAGKDVKALVDTGCLYNLISLACVDRLG 141
           VP++    + NQ++ +    SE+ D    S + A       VD+      + +  VDR  
Sbjct: 599 VPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKA-------VDSSSEEIEVEVPVVDRRN 651

Query: 142 LKEHVKSHKHEGEK 155
           L+   K HK   +K
Sbjct: 652 LRRKAKGHKGPAKK 665


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 28.1 bits (61), Expect = 7.1
 Identities = 20/74 (27%), Positives = 36/74 (48%)

Query: 4   SGLLTEGGRKETDMREAASLRQQRRMKQAVQFIHKDSADLLPLDGLKKLGSSKDMQPHNI 63
           SG L    ++  D +  A L++ RR+ Q V+F  +D  D+L L+  + L   K  +   +
Sbjct: 792 SGYLHLLYKRPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLV 851

Query: 64  LQRRLMETNLSKLR 77
            +R  +   L+  R
Sbjct: 852 PERETLFNTLANNR 865


>gi|13569922 NUAK family, SNF1-like kinase, 2 [Homo sapiens]
          Length = 628

 Score = 27.7 bits (60), Expect = 9.3
 Identities = 16/59 (27%), Positives = 27/59 (45%), Gaps = 4/59 (6%)

Query: 10  GGRKETDMREAASLRQQRRMKQAVQFIHKDSADLLPLDGLKKLGSSKDMQPHNILQRRL 68
           GG     +    SL++ R+     Q +H D+AD    D   + G S    P  IL++++
Sbjct: 361 GGSTTPGLERQHSLKKSRKENDMAQSLHSDTAD----DTAHRPGKSNLKLPKGILKKKV 415


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,423,561
Number of Sequences: 37866
Number of extensions: 343968
Number of successful extensions: 836
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 824
Number of HSP's gapped (non-prelim): 12
length of query: 241
length of database: 18,247,518
effective HSP length: 99
effective length of query: 142
effective length of database: 14,498,784
effective search space: 2058827328
effective search space used: 2058827328
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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