Guide to the Human Genome
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Search of human proteins with 156139127

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156139127 hypothetical protein LOC80007 [Homo sapiens]
         (445 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156139127 hypothetical protein LOC80007 [Homo sapiens]             899   0.0  
gi|110224479 prosaposin isoform c preproprotein [Homo sapiens]         34   0.31 
gi|110224476 prosaposin isoform b preproprotein [Homo sapiens]         34   0.31 
gi|11386147 prosaposin isoform a preproprotein [Homo sapiens]          34   0.31 
gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]           33   0.52 
gi|4504335 kalirin, RhoGEF kinase isoform 2 [Homo sapiens]             33   0.52 
gi|4507693 tuberous sclerosis 1 protein isoform 1 [Homo sapiens]       32   1.2  
gi|241666464 tuberous sclerosis 1 protein isoform 4 [Homo sapiens]     32   1.2  
gi|241666462 tuberous sclerosis 1 protein isoform 3 [Homo sapiens]     32   1.2  
gi|91992162 mutL homolog 3 isoform 1 [Homo sapiens]                    32   1.5  
gi|91992160 mutL homolog 3 isoform 2 [Homo sapiens]                    32   1.5  
gi|13699824 kinesin family member 11 [Homo sapiens]                    31   2.6  
gi|24797086 importin 5 [Homo sapiens]                                  31   2.6  
gi|13699818 cytochrome P450, family 2, subfamily C, polypeptide ...    30   3.4  
gi|7705433 eukaryotic translation initiation factor 3 subunit 6 ...    30   3.4  
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]    30   4.4  
gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]               30   5.8  
gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]               30   5.8  
gi|197313728 pleckstrin homology-like domain, family B, member 2...    30   5.8  
gi|21955172 pleckstrin homology-like domain, family B, member 2 ...    30   5.8  
gi|197313732 pleckstrin homology-like domain, family B, member 2...    29   7.5  
gi|197313730 pleckstrin homology-like domain, family B, member 2...    29   7.5  
gi|191252785 centrobin, centrosomal BRCA2 interacting protein is...    29   9.9  
gi|80861396 centrobin, centrosomal BRCA2 interacting protein iso...    29   9.9  

>gi|156139127 hypothetical protein LOC80007 [Homo sapiens]
          Length = 445

 Score =  899 bits (2322), Expect = 0.0
 Identities = 445/445 (100%), Positives = 445/445 (100%)

Query: 1   METRTEDGGLTRRPTLASSWDVAGGALTHSLLLTRAGLGPGDFDWEELLAPPAPGQDLVI 60
           METRTEDGGLTRRPTLASSWDVAGGALTHSLLLTRAGLGPGDFDWEELLAPPAPGQDLVI
Sbjct: 1   METRTEDGGLTRRPTLASSWDVAGGALTHSLLLTRAGLGPGDFDWEELLAPPAPGQDLVI 60

Query: 61  LKRNHNNKDENPCFLYLRCGPDGGEEIASIGILSSARNMEVYLGEEYCGTSRGKNVCTVL 120
           LKRNHNNKDENPCFLYLRCGPDGGEEIASIGILSSARNMEVYLGEEYCGTSRGKNVCTVL
Sbjct: 61  LKRNHNNKDENPCFLYLRCGPDGGEEIASIGILSSARNMEVYLGEEYCGTSRGKNVCTVL 120

Query: 121 DDSEHEKIILYKKNLKLESSTHACKIKLLSFGERQCVFISKVVVHMRSVFANSSTSSPAL 180
           DDSEHEKIILYKKNLKLESSTHACKIKLLSFGERQCVFISKVVVHMRSVFANSSTSSPAL
Sbjct: 121 DDSEHEKIILYKKNLKLESSTHACKIKLLSFGERQCVFISKVVVHMRSVFANSSTSSPAL 180

Query: 181 GSRIDLDKVQTIMESMGSKLSPGAQQLMDMVRCQQRNCIPIGEQLQSVLGNSGYKHMIGL 240
           GSRIDLDKVQTIMESMGSKLSPGAQQLMDMVRCQQRNCIPIGEQLQSVLGNSGYKHMIGL
Sbjct: 181 GSRIDLDKVQTIMESMGSKLSPGAQQLMDMVRCQQRNCIPIGEQLQSVLGNSGYKHMIGL 240

Query: 241 QSSSTLGTLNKSSSTPFPFRTGLTSGNVTENLQTYIDKSTQLPGGENSTKLDECKVMPQN 300
           QSSSTLGTLNKSSSTPFPFRTGLTSGNVTENLQTYIDKSTQLPGGENSTKLDECKVMPQN
Sbjct: 241 QSSSTLGTLNKSSSTPFPFRTGLTSGNVTENLQTYIDKSTQLPGGENSTKLDECKVMPQN 300

Query: 301 HSFLENDLKNAMASFLPKKVSDNSNIPNSELLPFLQNLCSQVNHLHVGNKTECQENITKH 360
           HSFLENDLKNAMASFLPKKVSDNSNIPNSELLPFLQNLCSQVNHLHVGNKTECQENITKH
Sbjct: 301 HSFLENDLKNAMASFLPKKVSDNSNIPNSELLPFLQNLCSQVNHLHVGNKTECQENITKH 360

Query: 361 GERILGVGMEEQSICSYLEKILSKNMELMEKKLMDYIDQRIHELQEHIDDKIALLLDLLQ 420
           GERILGVGMEEQSICSYLEKILSKNMELMEKKLMDYIDQRIHELQEHIDDKIALLLDLLQ
Sbjct: 361 GERILGVGMEEQSICSYLEKILSKNMELMEKKLMDYIDQRIHELQEHIDDKIALLLDLLQ 420

Query: 421 NPNSPPTGIPLRHYDSGERLSNGER 445
           NPNSPPTGIPLRHYDSGERLSNGER
Sbjct: 421 NPNSPPTGIPLRHYDSGERLSNGER 445


>gi|110224479 prosaposin isoform c preproprotein [Homo sapiens]
          Length = 526

 Score = 33.9 bits (76), Expect = 0.31
 Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 23/119 (19%)

Query: 305 ENDLKNAMASFLPKKVSD--NSNIPNSELLPFLQNLCSQVNHLHVGNKTECQENITKHGE 362
           ++D+   +  FL K+V+   ++N    E+L     +CS+   L      ECQE +  +G 
Sbjct: 312 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSK---LPKSLSEECQEVVDTYGS 368

Query: 363 RILGVGMEEQS---ICSYLEKILSKNMELME---------------KKLMDYIDQRIHE 403
            IL + +EE S   +CS L       +  +                KKL+ Y+D+ + +
Sbjct: 369 SILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEK 427


>gi|110224476 prosaposin isoform b preproprotein [Homo sapiens]
          Length = 527

 Score = 33.9 bits (76), Expect = 0.31
 Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 23/119 (19%)

Query: 305 ENDLKNAMASFLPKKVSD--NSNIPNSELLPFLQNLCSQVNHLHVGNKTECQENITKHGE 362
           ++D+   +  FL K+V+   ++N    E+L     +CS+   L      ECQE +  +G 
Sbjct: 313 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSK---LPKSLSEECQEVVDTYGS 369

Query: 363 RILGVGMEEQS---ICSYLEKILSKNMELME---------------KKLMDYIDQRIHE 403
            IL + +EE S   +CS L       +  +                KKL+ Y+D+ + +
Sbjct: 370 SILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEK 428


>gi|11386147 prosaposin isoform a preproprotein [Homo sapiens]
          Length = 524

 Score = 33.9 bits (76), Expect = 0.31
 Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 23/119 (19%)

Query: 305 ENDLKNAMASFLPKKVSD--NSNIPNSELLPFLQNLCSQVNHLHVGNKTECQENITKHGE 362
           ++D+   +  FL K+V+   ++N    E+L     +CS+   L      ECQE +  +G 
Sbjct: 310 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSK---LPKSLSEECQEVVDTYGS 366

Query: 363 RILGVGMEEQS---ICSYLEKILSKNMELME---------------KKLMDYIDQRIHE 403
            IL + +EE S   +CS L       +  +                KKL+ Y+D+ + +
Sbjct: 367 SILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEK 425


>gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]
          Length = 2986

 Score = 33.1 bits (74), Expect = 0.52
 Identities = 29/130 (22%), Positives = 64/130 (49%), Gaps = 12/130 (9%)

Query: 290 KLDECKVMPQNHSFLENDLKNAMASFLPKKVSDNSNIP-NSELLPFLQNLCSQVNHLHVG 348
           +LD+ +V  +    L ++ K  +  FL  ++ +   I   +EL  + ++L  Q+N  +  
Sbjct: 746 QLDDAQVQMEE---LFHERKIKLDIFLQLRIFEQYTIEVTAELDAWNEDLLRQMNDFNTE 802

Query: 349 NKTECQENITKHGERILGVG-------MEEQSICSYLEKILSKNMELMEKKLMDYIDQRI 401
           + T  ++ + +H ER L +         + Q +  Y+ ++ +  +EL+ +K +D   Q +
Sbjct: 803 DLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYITEVQASGIELICEKDIDLAAQ-V 861

Query: 402 HELQEHIDDK 411
            EL E + +K
Sbjct: 862 QELLEFLHEK 871


>gi|4504335 kalirin, RhoGEF kinase isoform 2 [Homo sapiens]
          Length = 1663

 Score = 33.1 bits (74), Expect = 0.52
 Identities = 29/130 (22%), Positives = 64/130 (49%), Gaps = 12/130 (9%)

Query: 290 KLDECKVMPQNHSFLENDLKNAMASFLPKKVSDNSNIP-NSELLPFLQNLCSQVNHLHVG 348
           +LD+ +V  +    L ++ K  +  FL  ++ +   I   +EL  + ++L  Q+N  +  
Sbjct: 746 QLDDAQVQMEE---LFHERKIKLDIFLQLRIFEQYTIEVTAELDAWNEDLLRQMNDFNTE 802

Query: 349 NKTECQENITKHGERILGVG-------MEEQSICSYLEKILSKNMELMEKKLMDYIDQRI 401
           + T  ++ + +H ER L +         + Q +  Y+ ++ +  +EL+ +K +D   Q +
Sbjct: 803 DLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYITEVQASGIELICEKDIDLAAQ-V 861

Query: 402 HELQEHIDDK 411
            EL E + +K
Sbjct: 862 QELLEFLHEK 871


>gi|4507693 tuberous sclerosis 1 protein isoform 1 [Homo sapiens]
          Length = 1164

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 36/142 (25%), Positives = 67/142 (47%), Gaps = 21/142 (14%)

Query: 286 ENSTKLDECKVMPQNHSFLENDLKNA---------MASFLPKKVSDNSNIPNS-ELLPFL 335
           E  TKL++C+ M      L  +LK A         + S + +K+S++ ++    E L   
Sbjct: 795 ELQTKLEDCRNMIAE---LRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQ 851

Query: 336 QNLCSQVNHLHVGNKTECQENITKHGERILGVGMEEQSICSYLEKILSKNMELMEKKLMD 395
             +  +VN L++      ++   KH +    V M + +    LEK  +++  L + + +D
Sbjct: 852 LLVLGEVNELYL------EQLQNKHSDTTKEVEMMKAAYRKELEK--NRSHVLQQTQRLD 903

Query: 396 YIDQRIHELQEHIDDKIALLLD 417
              +RI EL+ H+  K  LLL+
Sbjct: 904 TSQKRILELESHLAKKDHLLLE 925


>gi|241666464 tuberous sclerosis 1 protein isoform 4 [Homo sapiens]
          Length = 1113

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 36/142 (25%), Positives = 67/142 (47%), Gaps = 21/142 (14%)

Query: 286 ENSTKLDECKVMPQNHSFLENDLKNA---------MASFLPKKVSDNSNIPNS-ELLPFL 335
           E  TKL++C+ M      L  +LK A         + S + +K+S++ ++    E L   
Sbjct: 744 ELQTKLEDCRNMIAE---LRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQ 800

Query: 336 QNLCSQVNHLHVGNKTECQENITKHGERILGVGMEEQSICSYLEKILSKNMELMEKKLMD 395
             +  +VN L++      ++   KH +    V M + +    LEK  +++  L + + +D
Sbjct: 801 LLVLGEVNELYL------EQLQNKHSDTTKEVEMMKAAYRKELEK--NRSHVLQQTQRLD 852

Query: 396 YIDQRIHELQEHIDDKIALLLD 417
              +RI EL+ H+  K  LLL+
Sbjct: 853 TSQKRILELESHLAKKDHLLLE 874


>gi|241666462 tuberous sclerosis 1 protein isoform 3 [Homo sapiens]
          Length = 1163

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 36/142 (25%), Positives = 67/142 (47%), Gaps = 21/142 (14%)

Query: 286 ENSTKLDECKVMPQNHSFLENDLKNA---------MASFLPKKVSDNSNIPNS-ELLPFL 335
           E  TKL++C+ M      L  +LK A         + S + +K+S++ ++    E L   
Sbjct: 794 ELQTKLEDCRNMIAE---LRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQ 850

Query: 336 QNLCSQVNHLHVGNKTECQENITKHGERILGVGMEEQSICSYLEKILSKNMELMEKKLMD 395
             +  +VN L++      ++   KH +    V M + +    LEK  +++  L + + +D
Sbjct: 851 LLVLGEVNELYL------EQLQNKHSDTTKEVEMMKAAYRKELEK--NRSHVLQQTQRLD 902

Query: 396 YIDQRIHELQEHIDDKIALLLD 417
              +RI EL+ H+  K  LLL+
Sbjct: 903 TSQKRILELESHLAKKDHLLLE 924


>gi|91992162 mutL homolog 3 isoform 1 [Homo sapiens]
          Length = 1453

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 38/183 (20%), Positives = 66/183 (36%), Gaps = 18/183 (9%)

Query: 240 LQSSSTLGTLNKSS----STPFPFRTGLTSGN-VTENLQTYIDKSTQLPGGENSTKLDEC 294
           L  SS LG+L K          P  T +   N VT NL   ++    L         D C
Sbjct: 745 LSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTTNLSLQVEPDILLKDKNRLENSDVC 804

Query: 295 KVMPQNHSFLENDLKNAMASFLPKKVSDNSNIPNSELLPFLQNL-CSQVNHLHVGNKTEC 353
           K+    HS  ++  + A            S+I NSE  PF ++  C +     +      
Sbjct: 805 KITTMEHSDSDSSCQPA------------SHILNSEKFPFSKDEDCLEQQMPSLRESPMT 852

Query: 354 QENITKHGERILGVGMEEQSICSYLEKILSKNMELMEKKLMDYIDQRIHELQEHIDDKIA 413
            + ++    + L +    +S+ S L ++     E     +M   ++  +      D K+ 
Sbjct: 853 LKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELPNSDSSRKDSKLC 912

Query: 414 LLL 416
            +L
Sbjct: 913 SVL 915


>gi|91992160 mutL homolog 3 isoform 2 [Homo sapiens]
          Length = 1429

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 38/183 (20%), Positives = 66/183 (36%), Gaps = 18/183 (9%)

Query: 240 LQSSSTLGTLNKSS----STPFPFRTGLTSGN-VTENLQTYIDKSTQLPGGENSTKLDEC 294
           L  SS LG+L K          P  T +   N VT NL   ++    L         D C
Sbjct: 745 LSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTTNLSLQVEPDILLKDKNRLENSDVC 804

Query: 295 KVMPQNHSFLENDLKNAMASFLPKKVSDNSNIPNSELLPFLQNL-CSQVNHLHVGNKTEC 353
           K+    HS  ++  + A            S+I NSE  PF ++  C +     +      
Sbjct: 805 KITTMEHSDSDSSCQPA------------SHILNSEKFPFSKDEDCLEQQMPSLRESPMT 852

Query: 354 QENITKHGERILGVGMEEQSICSYLEKILSKNMELMEKKLMDYIDQRIHELQEHIDDKIA 413
            + ++    + L +    +S+ S L ++     E     +M   ++  +      D K+ 
Sbjct: 853 LKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELPNSDSSRKDSKLC 912

Query: 414 LLL 416
            +L
Sbjct: 913 SVL 915


>gi|13699824 kinesin family member 11 [Homo sapiens]
          Length = 1056

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 30/145 (20%), Positives = 65/145 (44%), Gaps = 14/145 (9%)

Query: 267 NVTENLQTYIDKSTQLPGGENSTKLDECKVMPQNHSFLE-------NDLKNAMASFLPKK 319
           +    L   ++++T+   G +S KLD  K + Q+++  +       N L N M   +   
Sbjct: 494 DAASKLLNTVEETTKDVSGLHS-KLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEELIKDG 552

Query: 320 VSDNSNIPNSELLPFLQNLCSQVNHLH------VGNKTECQENITKHGERILGVGMEEQS 373
            S    +       F   L S V+ L       +G+ T   EN++ H  +I  + ++EQS
Sbjct: 553 SSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHVSQIFNMILKEQS 612

Query: 374 ICSYLEKILSKNMELMEKKLMDYID 398
           + +  + +L + + +++  L+  ++
Sbjct: 613 LAAESKTVLQELINVLKTDLLSSLE 637


>gi|24797086 importin 5 [Homo sapiens]
          Length = 1115

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 13/101 (12%)

Query: 320 VSDNSNIPNSELLPFLQNLCSQVNHLHVGNKTECQENITKHGERILGVGMEEQSICSYLE 379
           ++   + P S L+P+L NL   V HLH     + QE I K  + +L     EQ + S   
Sbjct: 485 INFTEDCPKSLLIPYLDNL---VKHLHSIMVLKLQELIQKGTKLVL-----EQVVTS--- 533

Query: 380 KILSKNMELMEKKLMDYIDQRIHELQEHIDDKIALLLDLLQ 420
             ++   +  E+K + Y D  +  L+  +++ +   L LL+
Sbjct: 534 --IASVADTAEEKFVPYYDLFMPSLKHIVENAVQKELRLLR 572


>gi|13699818 cytochrome P450, family 2, subfamily C, polypeptide 9
           [Homo sapiens]
          Length = 490

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 26/118 (22%), Positives = 51/118 (43%), Gaps = 7/118 (5%)

Query: 295 KVMPQNHSFLENDLKNAMASFLPKKVSDNSNIPNSELLPFLQNLCSQVNHLHVGNKTECQ 354
           KV     S   N+ ++ +  FL K   +  N P+   +  L+N    +     G  TE  
Sbjct: 247 KVKEHQESMDMNNPQDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDL----FGAGTETT 302

Query: 355 ENITKHGERILGVGMEEQS-ICSYLEKILSKNME--LMEKKLMDYIDQRIHELQEHID 409
               ++   +L    E  + +   +E+++ +N    + ++  M Y D  +HE+Q +ID
Sbjct: 303 STTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYID 360


>gi|7705433 eukaryotic translation initiation factor 3 subunit 6
           interacting protein [Homo sapiens]
          Length = 564

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 15/57 (26%), Positives = 30/57 (52%), Gaps = 6/57 (10%)

Query: 371 EQSICSYLEKILSKNMELMEKKLMDYIDQRIHELQ------EHIDDKIALLLDLLQN 421
           EQ     + +++   ++   K + D IDQ+++ELQ      + ID K+  + D+ +N
Sbjct: 41  EQQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYELQASRVSSDVIDQKVYEIQDIYEN 97


>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
          Length = 482

 Score = 30.0 bits (66), Expect = 4.4
 Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 26/110 (23%)

Query: 246 LGTLNKSSSTPFPFRTGLTSGNVTENLQTYIDKSTQLPGGENSTKLDECKVMPQNHSFLE 305
           L +L +    P   + GL+S    +N +   D         NS +L EC+ +    S   
Sbjct: 256 LESLKREGKEPLVLKGGLSS--FKQNHENLCD---------NSLQLQECREVGGGAS--- 301

Query: 306 NDLKNAMASFLPKKVSDNSNIPNSELLPFLQNLCSQVNHLHVGNKTECQE 355
                A +S LP+ +    +I N+EL P L         L +GN+ + Q+
Sbjct: 302 -----AASSLLPQPIPTTPDIENAELTPILP-------FLFLGNEQDAQD 339


>gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]
          Length = 2416

 Score = 29.6 bits (65), Expect = 5.8
 Identities = 32/138 (23%), Positives = 57/138 (41%), Gaps = 19/138 (13%)

Query: 219  IPIGEQLQSVLGNSGYKHMIGLQSSSTLGTLNKSSSTPFPFRTGLTSGNVTENLQTYIDK 278
            +P GE L++     G + + GL S   L T    ++      +GL SG V E     +++
Sbjct: 1280 LPSGEVLETTA--PGVEEISGLPSGEVLET----TAPGVDEISGLPSGEVLETTAPGVEE 1333

Query: 279  STQLPGGE----NSTKLDECKVMPQNHSFLENDLKNAMASFLPKKVSDNSNIPNSELLPF 334
             + LP GE    +++ + +   +P     LE  +           V D S +P+ E++  
Sbjct: 1334 ISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSG---------VEDISGLPSGEVVET 1384

Query: 335  LQNLCSQVNHLHVGNKTE 352
              +    V+ L  G   E
Sbjct: 1385 SASGIEDVSELPSGEGLE 1402


>gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]
          Length = 2317

 Score = 29.6 bits (65), Expect = 5.8
 Identities = 32/138 (23%), Positives = 57/138 (41%), Gaps = 19/138 (13%)

Query: 219  IPIGEQLQSVLGNSGYKHMIGLQSSSTLGTLNKSSSTPFPFRTGLTSGNVTENLQTYIDK 278
            +P GE L++     G + + GL S   L T    ++      +GL SG V E     +++
Sbjct: 1280 LPSGEVLETTA--PGVEEISGLPSGEVLET----TAPGVDEISGLPSGEVLETTAPGVEE 1333

Query: 279  STQLPGGE----NSTKLDECKVMPQNHSFLENDLKNAMASFLPKKVSDNSNIPNSELLPF 334
             + LP GE    +++ + +   +P     LE  +           V D S +P+ E++  
Sbjct: 1334 ISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSG---------VEDISGLPSGEVVET 1384

Query: 335  LQNLCSQVNHLHVGNKTE 352
              +    V+ L  G   E
Sbjct: 1385 SASGIEDVSELPSGEGLE 1402


>gi|197313728 pleckstrin homology-like domain, family B, member 2
           isoform b [Homo sapiens]
          Length = 1237

 Score = 29.6 bits (65), Expect = 5.8
 Identities = 31/126 (24%), Positives = 64/126 (50%), Gaps = 9/126 (7%)

Query: 298 PQNHSFLENDLKNAMASFLPKKVSDNSNIPNSELLPFLQNLCSQVNHLHVGNKTECQENI 357
           P + +F +   +++  S LPK     S    S+ L  ++    +   + + N  E ++ I
Sbjct: 580 PPSSTFPKASSESSYLSILPKTPEGISEEQRSQELAAME----ETRIVILNNLEELKQKI 635

Query: 358 TKHGERILGVGMEEQSICSYLE-KILSKNMELM-EKKLMDYIDQRIHELQEHI---DDKI 412
               +++     E    C+ L+ +  S+  ELM EK+++D+++++I EL+++I     K 
Sbjct: 636 KDINDQMDESFRELDMECALLDGEQKSETTELMKEKEILDHLNRKIAELEKNIVGEKTKD 695

Query: 413 ALLLDL 418
           A LLD+
Sbjct: 696 ADLLDV 701


>gi|21955172 pleckstrin homology-like domain, family B, member 2
           isoform c [Homo sapiens]
          Length = 1210

 Score = 29.6 bits (65), Expect = 5.8
 Identities = 31/126 (24%), Positives = 64/126 (50%), Gaps = 9/126 (7%)

Query: 298 PQNHSFLENDLKNAMASFLPKKVSDNSNIPNSELLPFLQNLCSQVNHLHVGNKTECQENI 357
           P + +F +   +++  S LPK     S    S+ L  ++    +   + + N  E ++ I
Sbjct: 553 PPSSTFPKASSESSYLSILPKTPEGISEEQRSQELAAME----ETRIVILNNLEELKQKI 608

Query: 358 TKHGERILGVGMEEQSICSYLE-KILSKNMELM-EKKLMDYIDQRIHELQEHI---DDKI 412
               +++     E    C+ L+ +  S+  ELM EK+++D+++++I EL+++I     K 
Sbjct: 609 KDINDQMDESFRELDMECALLDGEQKSETTELMKEKEILDHLNRKIAELEKNIVGEKTKD 668

Query: 413 ALLLDL 418
           A LLD+
Sbjct: 669 ADLLDV 674


>gi|197313732 pleckstrin homology-like domain, family B, member 2
           isoform a [Homo sapiens]
          Length = 1253

 Score = 29.3 bits (64), Expect = 7.5
 Identities = 26/113 (23%), Positives = 58/113 (51%), Gaps = 6/113 (5%)

Query: 298 PQNHSFLENDLKNAMASFLPKKVSDNSNIPNSELLPFLQNLCSQVNHLHVGNKTECQENI 357
           P + +F +   +++  S LPK     S    S+ L  ++    +   + + N  E ++ I
Sbjct: 553 PPSSTFPKASSESSYLSILPKTPEGISEEQRSQELAAME----ETRIVILNNLEELKQKI 608

Query: 358 TKHGERILGVGMEEQSICSYLE-KILSKNMELM-EKKLMDYIDQRIHELQEHI 408
               +++     E    C+ L+ +  S+  ELM EK+++D+++++I EL+++I
Sbjct: 609 KDINDQMDESFRELDMECALLDGEQKSETTELMKEKEILDHLNRKIAELEKNI 661


>gi|197313730 pleckstrin homology-like domain, family B, member 2
           isoform a [Homo sapiens]
          Length = 1253

 Score = 29.3 bits (64), Expect = 7.5
 Identities = 26/113 (23%), Positives = 58/113 (51%), Gaps = 6/113 (5%)

Query: 298 PQNHSFLENDLKNAMASFLPKKVSDNSNIPNSELLPFLQNLCSQVNHLHVGNKTECQENI 357
           P + +F +   +++  S LPK     S    S+ L  ++    +   + + N  E ++ I
Sbjct: 553 PPSSTFPKASSESSYLSILPKTPEGISEEQRSQELAAME----ETRIVILNNLEELKQKI 608

Query: 358 TKHGERILGVGMEEQSICSYLE-KILSKNMELM-EKKLMDYIDQRIHELQEHI 408
               +++     E    C+ L+ +  S+  ELM EK+++D+++++I EL+++I
Sbjct: 609 KDINDQMDESFRELDMECALLDGEQKSETTELMKEKEILDHLNRKIAELEKNI 661


>gi|191252785 centrobin, centrosomal BRCA2 interacting protein
           isoform alpha [Homo sapiens]
          Length = 903

 Score = 28.9 bits (63), Expect = 9.9
 Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 11/97 (11%)

Query: 336 QNLCSQVNHLHV--GNKTECQENITKHGERILGVGMEEQSICSYLEKILSKNMELMEKKL 393
           Q L SQ+    V    + E Q+ + +  E  L +  E+  +C    ++ S N +L E+++
Sbjct: 494 QELASQLAQFKVEMAEREERQQQVAEDYE--LRLAREQARVC----ELQSGNQQLEEQRV 547

Query: 394 MDYIDQRIHELQEHIDDKIALLLDLL--QNPNSPPTG 428
            + +++    LQ H D+   LL   L   NP +PP G
Sbjct: 548 -ELVERLQAMLQAHWDEANQLLSTTLPPPNPPAPPAG 583


>gi|80861396 centrobin, centrosomal BRCA2 interacting protein
           isoform beta [Homo sapiens]
          Length = 925

 Score = 28.9 bits (63), Expect = 9.9
 Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 11/97 (11%)

Query: 336 QNLCSQVNHLHV--GNKTECQENITKHGERILGVGMEEQSICSYLEKILSKNMELMEKKL 393
           Q L SQ+    V    + E Q+ + +  E  L +  E+  +C    ++ S N +L E+++
Sbjct: 494 QELASQLAQFKVEMAEREERQQQVAEDYE--LRLAREQARVC----ELQSGNQQLEEQRV 547

Query: 394 MDYIDQRIHELQEHIDDKIALLLDLL--QNPNSPPTG 428
            + +++    LQ H D+   LL   L   NP +PP G
Sbjct: 548 -ELVERLQAMLQAHWDEANQLLSTTLPPPNPPAPPAG 583


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.133    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,164,900
Number of Sequences: 37866
Number of extensions: 843192
Number of successful extensions: 1718
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 1682
Number of HSP's gapped (non-prelim): 69
length of query: 445
length of database: 18,247,518
effective HSP length: 105
effective length of query: 340
effective length of database: 14,271,588
effective search space: 4852339920
effective search space used: 4852339920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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