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Search of human proteins with 15529972
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15529972 mitochondrial carrier triple repeat 1 [Homo
sapiens]
(297 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15529972 mitochondrial carrier triple repeat 1 [Homo sapiens] 607 e-174
gi|148276979 mitochondrial carrier triple repeat 2 [Homo sapiens] 583 e-167
gi|153792375 mitochondrial carrier triple repeat 6 [Homo sapiens] 160 2e-39
gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxy... 65 9e-11
gi|11225256 uncoupling protein 1 [Homo sapiens] 64 2e-10
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 61 1e-09
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 55 6e-08
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 55 1e-07
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 55 1e-07
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 53 3e-07
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 53 3e-07
gi|46094065 mitochondrial carrier family protein [Homo sapiens] 53 4e-07
gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens] 52 6e-07
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 51 1e-06
gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 51 1e-06
gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 50 3e-06
gi|13259541 uncoupling protein 2 [Homo sapiens] 47 2e-05
gi|7706306 solute carrier family 25, member 39 isoform b [Homo s... 47 2e-05
gi|219555665 solute carrier family 25, member 39 isoform a [Homo... 47 2e-05
gi|21361114 solute carrier family 25 (mitochondrial carrier; oxo... 47 2e-05
gi|41462412 solute carrier family 25, member 35 [Homo sapiens] 47 2e-05
gi|157388991 solute carrier family 25, member 36 isoform b [Homo... 47 3e-05
gi|108860679 solute carrier family 25, member 27 [Homo sapiens] 47 3e-05
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 47 3e-05
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 47 3e-05
gi|13899342 solute carrier [Homo sapiens] 47 3e-05
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 45 8e-05
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 45 8e-05
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 45 8e-05
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 45 8e-05
>gi|15529972 mitochondrial carrier triple repeat 1 [Homo sapiens]
Length = 297
Score = 607 bits (1565), Expect = e-174
Identities = 297/297 (100%), Positives = 297/297 (100%)
Query: 1 MMDSEAHEKRPPILTSSKQDISPHITNVGEMKHYLCGCCAAFNNVAITFPIQKVLFRQQL 60
MMDSEAHEKRPPILTSSKQDISPHITNVGEMKHYLCGCCAAFNNVAITFPIQKVLFRQQL
Sbjct: 1 MMDSEAHEKRPPILTSSKQDISPHITNVGEMKHYLCGCCAAFNNVAITFPIQKVLFRQQL 60
Query: 61 YGIKTRDAILQLRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFAT 120
YGIKTRDAILQLRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFAT
Sbjct: 61 YGIKTRDAILQLRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFAT 120
Query: 121 SGVAAVLAGTTEAIFTPLERVQTLLQDHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPIL 180
SGVAAVLAGTTEAIFTPLERVQTLLQDHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPIL
Sbjct: 121 SGVAAVLAGTTEAIFTPLERVQTLLQDHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPIL 180
Query: 181 FRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFICGGLLGAMLGFLFFPINVVKTRIQ 240
FRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFICGGLLGAMLGFLFFPINVVKTRIQ
Sbjct: 181 FRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFICGGLLGAMLGFLFFPINVVKTRIQ 240
Query: 241 SQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKVI 297
SQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKVI
Sbjct: 241 SQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKVI 297
>gi|148276979 mitochondrial carrier triple repeat 2 [Homo sapiens]
Length = 297
Score = 583 bits (1502), Expect = e-167
Identities = 285/297 (95%), Positives = 290/297 (97%)
Query: 1 MMDSEAHEKRPPILTSSKQDISPHITNVGEMKHYLCGCCAAFNNVAITFPIQKVLFRQQL 60
M+DSEAHEKRPPILTSSKQDISPHITNVGEMKHYLCGCCAAFNNVAIT+PIQKVLFRQQL
Sbjct: 1 MIDSEAHEKRPPILTSSKQDISPHITNVGEMKHYLCGCCAAFNNVAITYPIQKVLFRQQL 60
Query: 61 YGIKTRDAILQLRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFAT 120
YGIKTRDA+LQLRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLL KHV APEFAT
Sbjct: 61 YGIKTRDAVLQLRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFAT 120
Query: 121 SGVAAVLAGTTEAIFTPLERVQTLLQDHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPIL 180
GVAAVLAGT EAIFTPLERVQTLLQ+HKHHDKFTNTYQAFKALKCHGIGEYYRGLVPIL
Sbjct: 121 HGVAAVLAGTAEAIFTPLERVQTLLQNHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPIL 180
Query: 181 FRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFICGGLLGAMLGFLFFPINVVKTRIQ 240
FRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFI GGLLGAMLGFL FPINVVKTR+Q
Sbjct: 181 FRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQ 240
Query: 241 SQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKVI 297
SQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLK I
Sbjct: 241 SQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKFI 297
>gi|153792375 mitochondrial carrier triple repeat 6 [Homo sapiens]
Length = 307
Score = 160 bits (404), Expect = 2e-39
Identities = 93/269 (34%), Positives = 146/269 (54%), Gaps = 14/269 (5%)
Query: 34 YLCGCCAAFNNVAITFPIQKVLFRQQLYGIKTRDAILQLRRDGFRNLYRGILPPLMQKTT 93
Y G + F + +TFPI KV+FRQQ++ + +A+ QL +G + YRGI PPL+ KT
Sbjct: 31 YALGAVSNFMSTFLTFPIYKVVFRQQIHAMAVSEAVRQLWHEGPQYFYRGIYPPLLSKTL 90
Query: 94 TLALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGTTEAI-FTPLERVQTLLQDHKHHD 152
L+FG Y+ L C L V A +++G EA+ +P ERVQ +LQD +
Sbjct: 91 QGTLLFGTYDSLLCFL-SPVGPHTLGHRWAAGLMSGVVEAVALSPFERVQNVLQDGRKQA 149
Query: 153 KFTNTYQAFKALKCHGIG-----EYYRGLVPILFRNGLSNVLFFGLRGPIKEHLPTATTH 207
+F +T+ K +G+ YYRG P+L RN L + L+F + PI++ L A
Sbjct: 150 RFPSTFSILKEFNSYGLWGRLSLGYYRGFWPVLARNSLGSALYFSFKDPIQDGL--AEQG 207
Query: 208 SAHLVNDFICGGLLGAMLGFLFFPINVVKTRIQSQIGGEFQSFPKVF---QKIWLERDRK 264
H V + G + G + + +P+ V+ +QS IG +Q+ P ++ Q +W R RK
Sbjct: 208 LPHWVPALVSGSVNGTITCLVLYPLIVLVANMQSHIG--WQNMPSLWASAQDVWNTRGRK 265
Query: 265 LINLFRGAHLNYHRSLISWGIINATYEFL 293
L+ ++RG L RS ++WG+ A ++FL
Sbjct: 266 LLLIYRGGSLVILRSSVTWGLTTAIHDFL 294
>gi|13449279 solute carrier family 25 (mitochondrial
oxodicarboxylate carrier), member 21 [Homo sapiens]
Length = 299
Score = 64.7 bits (156), Expect = 9e-11
Identities = 63/233 (27%), Positives = 104/233 (44%), Gaps = 16/233 (6%)
Query: 23 PHITNVGEM-KHYLCGCCAAFNNVAITFPIQKVLFRQQLYGIKTRDAILQLRRDGFRNL- 80
P ++ V E + + G A + + P+ V R Q+ T + D FR +
Sbjct: 5 PEVSLVREASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIF 64
Query: 81 --------YRGILPPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGTTE 132
Y+GILPP++ +T A+ F +E LL +VS T +A + +G TE
Sbjct: 65 QMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLG-YVSLSPALTFAIAGLGSGLTE 123
Query: 133 AIFT-PLERVQTLLQDHKHH--DKFTNTYQAFKALKCHGIG--EYYRGLVPILFRNGLSN 187
AI P E V+ LQ +++ ++ + A + +K G G +GL L R+G+ N
Sbjct: 124 AIVVNPFEVVKVGLQANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFN 183
Query: 188 VLFFGLRGPIKEHLPTATTHSAHLVNDFICGGLLGAMLGFLFFPINVVKTRIQ 240
+++FG +K +P F G L G + + P +V K+RIQ
Sbjct: 184 MVYFGFYYNVKNMIPVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAKSRIQ 236
>gi|11225256 uncoupling protein 1 [Homo sapiens]
Length = 307
Score = 63.9 bits (154), Expect = 2e-10
Identities = 71/278 (25%), Positives = 123/278 (44%), Gaps = 36/278 (12%)
Query: 34 YLCGCCAAFNNVAITFPIQKVLFRQQLYGIKTRDAILQ-----------LRRDGFRNLYR 82
+ G A +V ITFP+ R Q+ G ++++ ++ +G LY
Sbjct: 18 FSAGIAACLADV-ITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEGRMKLYS 76
Query: 83 GILPPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGTTE---AIFT--P 137
G+ L ++ ++ +L GLY+ + L + E A S + +LAG T A+F P
Sbjct: 77 GLPAGLQRQISSASLRIGLYDTVQEFL---TAGKETAPSLGSKILAGLTTGGVAVFIGQP 133
Query: 138 LERVQTLLQDHKH----HDKFTNTYQAFKALKC-HGIGEYYRGLVPILFRNGLSN----V 188
E V+ LQ H ++T TY A++ + G+ ++G P L R+ + N V
Sbjct: 134 TEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTELV 193
Query: 189 LFFGLRGPIKEHLPTATTHSAHLVNDFICGGLLGAMLGFLFFPINVVKTRIQSQIGGEFQ 248
+ ++ ++ A HLV+ I G AM P++VVKTR + G+++
Sbjct: 194 TYDLMKEAFVKNNILADDVPCHLVSALIAGFCATAMSS----PVDVVKTRFINSPPGQYK 249
Query: 249 SFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGII 286
S P K++ F+G ++ R L SW +I
Sbjct: 250 SVPNCAMKVFTNEGPTA--FFKGLVPSFLR-LGSWNVI 284
Score = 33.9 bits (76), Expect = 0.18
Identities = 30/129 (23%), Positives = 55/129 (42%), Gaps = 2/129 (1%)
Query: 75 DGFRNLYRGILPPLMQKTTTLALMFGLYEDLS-CLLHKHVSAPEFATSGVAAVLAG-TTE 132
+G L++G P LM+ Y+ + + ++ A + V+A++AG
Sbjct: 168 EGLTGLWKGTTPNLMRSVIINCTELVTYDLMKEAFVKNNILADDVPCHLVSALIAGFCAT 227
Query: 133 AIFTPLERVQTLLQDHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLFFG 192
A+ +P++ V+T + + A K G +++GLVP R G NV+ F
Sbjct: 228 AMSSPVDVVKTRFINSPPGQYKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFV 287
Query: 193 LRGPIKEHL 201
+K L
Sbjct: 288 CFEQLKREL 296
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 60.8 bits (146), Expect = 1e-09
Identities = 74/290 (25%), Positives = 116/290 (40%), Gaps = 40/290 (13%)
Query: 35 LCGCCAAFNNVAITFPIQKVLFRQQLYGIKTRDAILQLR----RDGFRNLYRGILPPLMQ 90
+ GCCA KVL + + K LR ++GF LY+G +++
Sbjct: 45 IAGCCA--KTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYKGNGAMMIR 102
Query: 91 KTTTLALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGTTEAIFT-PLERVQTLLQDH- 148
A+ F +E L+ + +A +AG T I T PL+ V+ L
Sbjct: 103 IFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMTAVICTYPLDMVRVRLAFQV 162
Query: 149 KHHDKFTNTYQAFKAL--KCHGIGEYYRGLVPILFRN----GLSNVLFFGLRGPIKEHLP 202
K +T AFK + K G +YRGL+P + G+S F L+ H P
Sbjct: 163 KGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSHAP 222
Query: 203 TATTHSA-----------HLVNDFICGGLLGAMLGFLFFPINVVKTRIQSQIGGEFQSFP 251
T + H+ + +CGG+ GA+ + +P +V TR + Q+G F
Sbjct: 223 TLLGRPSSDNPNVLVLKTHV--NLLCGGVAGAIAQTISYPFDV--TRRRMQLGTVLPEFE 278
Query: 252 KVFQKIWLERDRKLI--------NLFRGAHLNYHRSLISWGIINATYEFL 293
K + + K + L+RG LNY R + S + TYE +
Sbjct: 279 KC---LTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELM 325
Score = 50.8 bits (120), Expect = 1e-06
Identities = 38/130 (29%), Positives = 60/130 (46%), Gaps = 5/130 (3%)
Query: 118 FATSGVAAVLAGTTEAIFTPLERVQTLLQDHKHHDKFTNTYQAFKAL-KCHGIGEYYRGL 176
F G+A A TT A PL+RV+ LLQ H HH K + A +A+ + G Y+G
Sbjct: 40 FLAGGIAGCCAKTTVA---PLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYKGN 96
Query: 177 VPILFRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFICGGLLGAMLGFLFFPINVVK 236
++ R + F K + T S H V+ + G + G +P+++V+
Sbjct: 97 GAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGH-VHRLMAGSMAGMTAVICTYPLDMVR 155
Query: 237 TRIQSQIGGE 246
R+ Q+ GE
Sbjct: 156 VRLAFQVKGE 165
>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
Length = 301
Score = 55.5 bits (132), Expect = 6e-08
Identities = 61/216 (28%), Positives = 99/216 (45%), Gaps = 26/216 (12%)
Query: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLHKH----VSAPEFATSGVAAVL 127
L R+G LYRG+ P++ T A+ F + L KH +S P+ +G +L
Sbjct: 63 LFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAG---ML 119
Query: 128 AGT-TEAIFTPLERVQTLL--QDHKHHDKFTNTYQAFKAL-KCHGIGEYYRGLVPILFRN 183
+G T I TP ER++ LL Q K+T T K L + GI Y+G V L R+
Sbjct: 120 SGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRD 179
Query: 184 GLSNVLFFGLRGPIKEHLPTATTHSAHLVND------FICGGLLGAMLGFLFFPINVVKT 237
++ ++F E L T V++ + GG+ G + P +V+K+
Sbjct: 180 VPASGMYF----MTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKS 235
Query: 238 RIQSQIGGEFQSFPKVFQKIWLE--RDRKLINLFRG 271
R Q+ G+ +P F+ + E RD + +L++G
Sbjct: 236 RFQTAPPGK---YPNGFRDVLRELIRDEGVTSLYKG 268
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 54.7 bits (130), Expect = 1e-07
Identities = 63/230 (27%), Positives = 98/230 (42%), Gaps = 16/230 (6%)
Query: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDL-SCLLHKHVSAPEFATSGVAAVLAGT 130
LR +GF LYRG+LP L+ A+ + + + +HK S P A +A AG
Sbjct: 382 LRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVP-LAAEILAGGCAGG 440
Query: 131 TEAIFT-PLERVQTLLQDHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVL 189
++ IFT PLE V+ LQ A ++ G Y+G R+ + +
Sbjct: 441 SQVIFTNPLEIVKIRLQVAGEITTGPRV-SALSVVRDLGFFGIYKGAKACFLRDIPFSAI 499
Query: 190 FFGLRGPIKEHLPTATTHSAHLVND---FICGGLLGAMLGFLFFPINVVKTRIQSQIGGE 246
+F P H+ + + V+ + G + G L P +V+KTR+Q
Sbjct: 500 YF----PCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAG 555
Query: 247 FQSFPKV---FQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFL 293
++ V F+KI E K L++GA RS +G+ TYE L
Sbjct: 556 QTTYSGVIDCFRKILREEGPKA--LWKGAGARVFRSSPQFGVTLLTYELL 603
Score = 45.4 bits (106), Expect = 6e-05
Identities = 44/180 (24%), Positives = 77/180 (42%), Gaps = 14/180 (7%)
Query: 108 LLHKHVSAPEFATSGVAAVLAGTTEAIFTPLERVQTLLQDHKHHDKFT------NTYQAF 161
LL SA F VA + T A++ P++ V+T +Q+ + F N++ F
Sbjct: 322 LLQVAESAYRFGLGSVAGAVGAT--AVY-PIDLVKTRMQNQRSTGSFVGELMYKNSFDCF 378
Query: 162 K-ALKCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFICGGL 220
K L+ G YRGL+P L + + +++ S L + + GG
Sbjct: 379 KKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF-MHKDGSVPLAAEILAGGC 437
Query: 221 LGAMLGFLFFPINVVKTRIQSQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSL 280
G P+ +VK R+ Q+ GE + P+V + + RD +++GA + R +
Sbjct: 438 AGGSQVIFTNPLEIVKIRL--QVAGEITTGPRV-SALSVVRDLGFFGIYKGAKACFLRDI 494
Score = 34.3 bits (77), Expect = 0.14
Identities = 32/117 (27%), Positives = 51/117 (43%), Gaps = 5/117 (4%)
Query: 35 LCGCCAAFNNVAITFPIQKVLFRQQLYGIKT---RDAILQLRRD-GFRNLYRGILPPLMQ 90
L G CA + V T P++ V R Q+ G T R + L + RD GF +Y+G ++
Sbjct: 433 LAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLR 492
Query: 91 KTTTLALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGTTEA-IFTPLERVQTLLQ 146
A+ F Y + + +A +AG A + TP + ++T LQ
Sbjct: 493 DIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQ 549
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 54.7 bits (130), Expect = 1e-07
Identities = 63/230 (27%), Positives = 98/230 (42%), Gaps = 16/230 (6%)
Query: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDL-SCLLHKHVSAPEFATSGVAAVLAGT 130
LR +GF LYRG+LP L+ A+ + + + +HK S P A +A AG
Sbjct: 383 LRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVP-LAAEILAGGCAGG 441
Query: 131 TEAIFT-PLERVQTLLQDHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVL 189
++ IFT PLE V+ LQ A ++ G Y+G R+ + +
Sbjct: 442 SQVIFTNPLEIVKIRLQVAGEITTGPRV-SALSVVRDLGFFGIYKGAKACFLRDIPFSAI 500
Query: 190 FFGLRGPIKEHLPTATTHSAHLVND---FICGGLLGAMLGFLFFPINVVKTRIQSQIGGE 246
+F P H+ + + V+ + G + G L P +V+KTR+Q
Sbjct: 501 YF----PCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAG 556
Query: 247 FQSFPKV---FQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFL 293
++ V F+KI E K L++GA RS +G+ TYE L
Sbjct: 557 QTTYSGVIDCFRKILREEGPKA--LWKGAGARVFRSSPQFGVTLLTYELL 604
Score = 45.4 bits (106), Expect = 6e-05
Identities = 44/180 (24%), Positives = 77/180 (42%), Gaps = 14/180 (7%)
Query: 108 LLHKHVSAPEFATSGVAAVLAGTTEAIFTPLERVQTLLQDHKHHDKFT------NTYQAF 161
LL SA F VA + T A++ P++ V+T +Q+ + F N++ F
Sbjct: 323 LLQVAESAYRFGLGSVAGAVGAT--AVY-PIDLVKTRMQNQRSTGSFVGELMYKNSFDCF 379
Query: 162 K-ALKCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFICGGL 220
K L+ G YRGL+P L + + +++ S L + + GG
Sbjct: 380 KKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF-MHKDGSVPLAAEILAGGC 438
Query: 221 LGAMLGFLFFPINVVKTRIQSQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSL 280
G P+ +VK R+ Q+ GE + P+V + + RD +++GA + R +
Sbjct: 439 AGGSQVIFTNPLEIVKIRL--QVAGEITTGPRV-SALSVVRDLGFFGIYKGAKACFLRDI 495
Score = 34.3 bits (77), Expect = 0.14
Identities = 32/117 (27%), Positives = 51/117 (43%), Gaps = 5/117 (4%)
Query: 35 LCGCCAAFNNVAITFPIQKVLFRQQLYGIKT---RDAILQLRRD-GFRNLYRGILPPLMQ 90
L G CA + V T P++ V R Q+ G T R + L + RD GF +Y+G ++
Sbjct: 434 LAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLR 493
Query: 91 KTTTLALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGTTEA-IFTPLERVQTLLQ 146
A+ F Y + + +A +AG A + TP + ++T LQ
Sbjct: 494 DIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQ 550
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 53.1 bits (126), Expect = 3e-07
Identities = 67/278 (24%), Positives = 120/278 (43%), Gaps = 25/278 (8%)
Query: 32 KHYLCGCCAAFNNVAITFPIQKVLFRQQLYGIKTRDAIL------QLRRDGFRNLYRGIL 85
+ L G A + T P+ ++ Q++G K+ + ++ G R+L+RG
Sbjct: 196 RQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNG 255
Query: 86 PPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGTTEAIFT-PLERVQTL 144
+++ A+ F YE LL + ++ +AG T F P+E ++T
Sbjct: 256 TNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTR 315
Query: 145 LQDHKHHDKFTNTYQ-AFKALKCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHLPT 203
L K +++ Y A K LK G+G +Y+G VP N L + + G+ + E L +
Sbjct: 316 LAVGKT-GQYSGIYDCAKKILKHEGLGAFYKGYVP----NLLGIIPYAGIDLAVYELLKS 370
Query: 204 --ATTHSAHLVNDFI-----CGGLLGAMLGFLFFPINVVKTRIQSQI---GGEFQSFPKV 253
+ VN + CG L +P+ +V+TR+Q+Q G + +
Sbjct: 371 YWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGL 430
Query: 254 FQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYE 291
F++I + + L+RG N+ + L + GI YE
Sbjct: 431 FRRIISKEG--IPGLYRGITPNFMKVLPAVGISYVVYE 466
Score = 37.0 bits (84), Expect = 0.021
Identities = 42/178 (23%), Positives = 72/178 (40%), Gaps = 7/178 (3%)
Query: 117 EFATSGVAAVLAGTTEAIFTPLERVQTLLQDHKHHDKFTNTYQAFKAL-KCHGIGEYYRG 175
+ G+A ++ T+ A PL+R++ ++Q H N + F+ + K GI +RG
Sbjct: 197 QLLAGGIAGAVSRTSTA---PLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRG 253
Query: 176 LVPILFRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFICGGLLGAMLGFLFFPINVV 235
+ + + F K+ L T FI G + GA +P+ V+
Sbjct: 254 NGTNVIKIAPETAVKFWAYEQYKKLL-TEEGQKIGTFERFISGSMAGATAQTFIYPMEVM 312
Query: 236 KTRIQSQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFL 293
KTR+ G++ +KI + L ++G N + GI A YE L
Sbjct: 313 KTRLAVGKTGQYSGIYDCAKKIL--KHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELL 368
Score = 29.6 bits (65), Expect = 3.3
Identities = 23/87 (26%), Positives = 38/87 (43%), Gaps = 8/87 (9%)
Query: 27 NVGEMKHYLCGCCAAFNNVAITFPIQKVLFRQQ----LYGIKTRDAILQLRR----DGFR 78
N G M CG ++ ++P+ V R Q L G + + RR +G
Sbjct: 382 NPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIP 441
Query: 79 NLYRGILPPLMQKTTTLALMFGLYEDL 105
LYRGI P M+ + + + +YE++
Sbjct: 442 GLYRGITPNFMKVLPAVGISYVVYENM 468
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 53.1 bits (126), Expect = 3e-07
Identities = 67/278 (24%), Positives = 120/278 (43%), Gaps = 25/278 (8%)
Query: 32 KHYLCGCCAAFNNVAITFPIQKVLFRQQLYGIKTRDAIL------QLRRDGFRNLYRGIL 85
+ L G A + T P+ ++ Q++G K+ + ++ G R+L+RG
Sbjct: 177 RQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNG 236
Query: 86 PPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGTTEAIFT-PLERVQTL 144
+++ A+ F YE LL + ++ +AG T F P+E ++T
Sbjct: 237 TNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTR 296
Query: 145 LQDHKHHDKFTNTYQ-AFKALKCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHLPT 203
L K +++ Y A K LK G+G +Y+G VP N L + + G+ + E L +
Sbjct: 297 LAVGKT-GQYSGIYDCAKKILKHEGLGAFYKGYVP----NLLGIIPYAGIDLAVYELLKS 351
Query: 204 --ATTHSAHLVNDFI-----CGGLLGAMLGFLFFPINVVKTRIQSQI---GGEFQSFPKV 253
+ VN + CG L +P+ +V+TR+Q+Q G + +
Sbjct: 352 YWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGL 411
Query: 254 FQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYE 291
F++I + + L+RG N+ + L + GI YE
Sbjct: 412 FRRIISKEG--IPGLYRGITPNFMKVLPAVGISYVVYE 447
Score = 37.0 bits (84), Expect = 0.021
Identities = 42/178 (23%), Positives = 72/178 (40%), Gaps = 7/178 (3%)
Query: 117 EFATSGVAAVLAGTTEAIFTPLERVQTLLQDHKHHDKFTNTYQAFKAL-KCHGIGEYYRG 175
+ G+A ++ T+ A PL+R++ ++Q H N + F+ + K GI +RG
Sbjct: 178 QLLAGGIAGAVSRTSTA---PLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRG 234
Query: 176 LVPILFRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFICGGLLGAMLGFLFFPINVV 235
+ + + F K+ L T FI G + GA +P+ V+
Sbjct: 235 NGTNVIKIAPETAVKFWAYEQYKKLL-TEEGQKIGTFERFISGSMAGATAQTFIYPMEVM 293
Query: 236 KTRIQSQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFL 293
KTR+ G++ +KI + L ++G N + GI A YE L
Sbjct: 294 KTRLAVGKTGQYSGIYDCAKKIL--KHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELL 349
Score = 29.6 bits (65), Expect = 3.3
Identities = 23/87 (26%), Positives = 38/87 (43%), Gaps = 8/87 (9%)
Query: 27 NVGEMKHYLCGCCAAFNNVAITFPIQKVLFRQQ----LYGIKTRDAILQLRR----DGFR 78
N G M CG ++ ++P+ V R Q L G + + RR +G
Sbjct: 363 NPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIP 422
Query: 79 NLYRGILPPLMQKTTTLALMFGLYEDL 105
LYRGI P M+ + + + +YE++
Sbjct: 423 GLYRGITPNFMKVLPAVGISYVVYENM 449
>gi|46094065 mitochondrial carrier family protein [Homo sapiens]
Length = 338
Score = 52.8 bits (125), Expect = 4e-07
Identities = 44/182 (24%), Positives = 84/182 (46%), Gaps = 4/182 (2%)
Query: 65 TRDAILQL-RRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFATSGV 123
T DA ++ R +G ++L+ G+ P L+ + F Y+ LS LL + E V
Sbjct: 87 TLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETCIPIV 146
Query: 124 AAVLAGT-TEAIFTPLERVQTLLQDHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFR 182
A ++A + +PLE ++T +Q K + + + K + G +RG P + R
Sbjct: 147 AGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSE-DGWISLWRGWAPTVLR 205
Query: 183 NGLSNVLFFGLRGPIKEHL-PTATTHSAHLVNDFICGGLLGAMLGFLFFPINVVKTRIQS 241
+ + +++ +K+ L + + + +F G L G+ P +VVKT+ Q+
Sbjct: 206 DVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVVKTQKQT 265
Query: 242 QI 243
Q+
Sbjct: 266 QL 267
>gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens]
Length = 321
Score = 52.0 bits (123), Expect = 6e-07
Identities = 55/243 (22%), Positives = 117/243 (48%), Gaps = 25/243 (10%)
Query: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLY----EDLSCLLHKHVSAPEFATSGVAAVL 127
L ++G ++L+RG+ P L+ + A+ F Y E + + + + ++G AA +
Sbjct: 82 LEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIFSAGSAAFI 141
Query: 128 AGTTEAIFTPLERVQTLLQDHK--HHDKFTNTYQAFKAL-KCHGIGEYYRGLVPILFRNG 184
T ++ P+ V+T +Q + K NT Q + + + GI +YRGL G
Sbjct: 142 ---TNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTASYA--G 196
Query: 185 LSN-VLFFGLRGPIKEHL---PTATTHSAHLVNDFICGGLLGAML------GFLFFPINV 234
+S ++ F + +K++L P A++ + N GL+ A + +P V
Sbjct: 197 ISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIAYPHEV 256
Query: 235 VKTRIQSQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLL 294
++TR++ + G +++SF + + ++ R+ + +RG R + + I+ +TYE ++
Sbjct: 257 IRTRLREE-GTKYKSFVQTARLVF--REEGYLAFYRGLFAQLIRQIPNTAIVLSTYELIV 313
Query: 295 KVI 297
++
Sbjct: 314 YLL 316
Score = 28.1 bits (61), Expect = 9.7
Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Query: 47 ITFPIQKVLFRQQLYGIKTRDAI----LQLRRDGFRNLYRGILPPLMQKTTTLALMFGLY 102
I +P + + R + G K + + L R +G+ YRG+ L+++ A++ Y
Sbjct: 250 IAYPHEVIRTRLREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLSTY 309
Query: 103 EDLSCLL 109
E + LL
Sbjct: 310 ELIVYLL 316
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 50.8 bits (120), Expect = 1e-06
Identities = 58/226 (25%), Positives = 90/226 (39%), Gaps = 8/226 (3%)
Query: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGTT 131
LR +GF LYRG++P L+ A+ + + + + + +A AG +
Sbjct: 380 LRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGS 439
Query: 132 EAIFT-PLERVQTLLQDHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLF 190
+ IFT PLE V+ LQ A L+ GI Y+G R+ + ++
Sbjct: 440 QVIFTNPLEIVKIRLQVAGEITTGPRV-SALNVLRDLGIFGLYKGAKACFLRDIPFSAIY 498
Query: 191 FGLRGPIKEHLPTATTHSAHLVNDFICGGLLGAMLGFLFFPINVVKTRIQSQIGGEFQSF 250
F + K L H L N G + G L P +V+KTR+Q ++
Sbjct: 499 FPVYAHCKLLLADENGHVGGL-NLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTY 557
Query: 251 PKV---FQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFL 293
V F+KI E ++G RS +G+ TYE L
Sbjct: 558 SGVIDCFRKILREEGPSA--FWKGTAARVFRSSPQFGVTLVTYELL 601
Score = 46.2 bits (108), Expect = 3e-05
Identities = 43/174 (24%), Positives = 77/174 (44%), Gaps = 14/174 (8%)
Query: 114 SAPEFATSGVAAVLAGTTEAIFTPLERVQTLLQDHKHHDK------FTNTYQAFK-ALKC 166
SA F VA + T A++ P++ V+T +Q+ + + N++ FK L+
Sbjct: 326 SAYRFTLGSVAGAVGAT--AVY-PIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRY 382
Query: 167 HGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFICGGLLGAMLG 226
G YRGL+P L + + +++ T S L + + GG G
Sbjct: 383 EGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKF-TRRDGSVPLPAEVLAGGCAGGSQV 441
Query: 227 FLFFPINVVKTRIQSQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSL 280
P+ +VK R+ Q+ GE + P+V + + RD + L++GA + R +
Sbjct: 442 IFTNPLEIVKIRL--QVAGEITTGPRV-SALNVLRDLGIFGLYKGAKACFLRDI 492
Score = 38.5 bits (88), Expect = 0.007
Identities = 41/159 (25%), Positives = 68/159 (42%), Gaps = 12/159 (7%)
Query: 35 LCGCCAAFNNVAITFPIQKVLFRQQLYGIKT---RDAILQLRRD-GFRNLYRGILPPLMQ 90
L G CA + V T P++ V R Q+ G T R + L + RD G LY+G ++
Sbjct: 431 LAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLR 490
Query: 91 KTTTLALMFGLYEDLSCLL---HKHVSAPEFATSGVAAVLAGTTEAIFTPLERVQTLLQ- 146
A+ F +Y LL + HV +G A + ++ TP + ++T LQ
Sbjct: 491 DIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAA--SLVTPADVIKTRLQV 548
Query: 147 -DHKHHDKFTNTYQAF-KALKCHGIGEYYRGLVPILFRN 183
++ F K L+ G +++G +FR+
Sbjct: 549 AARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRS 587
>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
Length = 338
Score = 50.8 bits (120), Expect = 1e-06
Identities = 65/316 (20%), Positives = 119/316 (37%), Gaps = 35/316 (11%)
Query: 2 MDSEAHEKRPPILTSSKQDISPHITNVGEMKHYLCGCCAAFNNVAITFPIQKVLFRQQ-- 59
MD ++ + + +D T+ H G A ++ +P+ V R Q
Sbjct: 17 MDGDSRDGGGGKDATGSEDYENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSL 76
Query: 60 ----------LYGIKTRDAILQLRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLL 109
+YG + +R +GF RG+ +M A+ F YE++ L
Sbjct: 77 SPDPKAQYTSIYGALKKI----MRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTL 132
Query: 110 HK--HVSAPEFATSGVAAVLAGTT-EAIFTPLERVQTLLQDHKHHDKFTNTYQAFKAL-K 165
+ H +G+A +A +A+ P E V+ LQ ++ + + + + +
Sbjct: 133 NDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQ--MYNSQHRSAISCIRTVWR 190
Query: 166 CHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFICGGLLGAML 225
G+G +YR L N + F ++E + T++ + I GGL GA+
Sbjct: 191 TEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTYNPQ--SHIISGGLAGALA 248
Query: 226 GFLFFPINVVKTRIQSQ---------IGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNY 276
P++V KT + +Q I G F+ ++ + L F+G
Sbjct: 249 AAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVY--QLNGLAGYFKGIQARV 306
Query: 277 HRSLISWGIINATYEF 292
+ S I + YEF
Sbjct: 307 IYQMPSTAISWSVYEF 322
>gi|157388989 solute carrier family 25, member 36 isoform a [Homo
sapiens]
Length = 311
Score = 49.7 bits (117), Expect = 3e-06
Identities = 60/244 (24%), Positives = 114/244 (46%), Gaps = 24/244 (9%)
Query: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGTT 131
L ++G R+L+RG+ P L+ + A+ F Y + L+ ++A +AG T
Sbjct: 72 LEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFT 131
Query: 132 EAIFT-PLERVQTLLQ--DHKHHDKFTNTYQAF-KALKCHGIGEYYRGLVPILFRNGLSN 187
T P+ ++T LQ ++ ++ K + G+ +YRG+ +
Sbjct: 132 AITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGM-SASYAGISET 190
Query: 188 VLFFGLRGPIKEHL---PTATT-----HSAHLVNDFICGGLLGAMLG-----FLFFPINV 234
V+ F + IK+ L TA+T S +DF+ G +L A + +P V
Sbjct: 191 VIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFV-GMMLAAATSKTCATTIAYPHEV 249
Query: 235 VKTRIQSQIGGEFQSFPKVFQKI-WLERDRKLINLFRGAHLNYHRSLISWGIINATYEFL 293
V+TR++ + G +++SF FQ + L ++ +L+RG + R + + I+ ATYE +
Sbjct: 250 VRTRLREE-GTKYRSF---FQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELV 305
Query: 294 LKVI 297
+ ++
Sbjct: 306 VYLL 309
Score = 30.8 bits (68), Expect = 1.5
Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 4/68 (5%)
Query: 47 ITFPIQKVLFRQQLYGIKTRDAI----LQLRRDGFRNLYRGILPPLMQKTTTLALMFGLY 102
I +P + V R + G K R L ++ +G+ +LYRG+ L+++ A+M Y
Sbjct: 243 IAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATY 302
Query: 103 EDLSCLLH 110
E + LL+
Sbjct: 303 ELVVYLLN 310
Score = 28.1 bits (61), Expect = 9.7
Identities = 14/25 (56%), Positives = 18/25 (72%), Gaps = 3/25 (12%)
Query: 217 CGGLLGAMLGFLFFPINVVKTRIQS 241
CGG +GA+L P+ VVKTR+QS
Sbjct: 15 CGGTVGAILTC---PLEVVKTRLQS 36
>gi|13259541 uncoupling protein 2 [Homo sapiens]
Length = 309
Score = 47.4 bits (111), Expect = 2e-05
Identities = 54/227 (23%), Positives = 95/227 (41%), Gaps = 28/227 (12%)
Query: 47 ITFPIQKVLFRQQLYGIK------TRDA---------ILQLRRDGFRNLYRGILPPLMQK 91
ITFP+ R Q+ G T A + +R +G R+LY G++ L ++
Sbjct: 30 ITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRTEGPRSLYNGLVAGLQRQ 89
Query: 92 TTTLALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGTTE-----AIFTPLERVQTLLQ 146
+ ++ GLY+ + + E A+ G + +LAG+T A+ P + V+ Q
Sbjct: 90 MSFASVRIGLYDSVK---QFYTKGSEHASIG-SRLLAGSTTGALAVAVAQPTDVVKVRFQ 145
Query: 147 DHKHHD---KFTNTYQAFKAL-KCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHLP 202
++ +T A+K + + G ++G P + RN + N IK+ L
Sbjct: 146 AQARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPNVARNAIVNCAELVTYDLIKDALL 205
Query: 203 TATTHSAHLVNDFICGGLLGAMLGFLFFPINVVKTRIQSQIGGEFQS 249
A + L F G + P++VVKTR + G++ S
Sbjct: 206 KANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYSS 252
Score = 37.4 bits (85), Expect = 0.016
Identities = 33/136 (24%), Positives = 57/136 (41%), Gaps = 2/136 (1%)
Query: 73 RRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLS-CLLHKHVSAPEFATSGVAAVLAG-T 130
R +GFR L++G P + + Y+ + LL ++ + +A AG
Sbjct: 168 REEGFRGLWKGTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFC 227
Query: 131 TEAIFTPLERVQTLLQDHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLF 190
T I +P++ V+T + + + A L+ G +Y+G +P R G NV+
Sbjct: 228 TTVIASPVDVVKTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVM 287
Query: 191 FGLRGPIKEHLPTATT 206
F +K L A T
Sbjct: 288 FVTYEQLKRALMAACT 303
Score = 30.4 bits (67), Expect = 2.0
Identities = 20/78 (25%), Positives = 32/78 (41%), Gaps = 5/78 (6%)
Query: 33 HYLCGCCAAFNNVAITFPIQKVLFRQQ-----LYGIKTRDAILQLRRDGFRNLYRGILPP 87
H+ A F I P+ V R Y A+ L+++G R Y+G +P
Sbjct: 217 HFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPS 276
Query: 88 LMQKTTTLALMFGLYEDL 105
++ + +MF YE L
Sbjct: 277 FLRLGSWNVVMFVTYEQL 294
>gi|7706306 solute carrier family 25, member 39 isoform b [Homo
sapiens]
Length = 351
Score = 47.4 bits (111), Expect = 2e-05
Identities = 59/239 (24%), Positives = 94/239 (39%), Gaps = 13/239 (5%)
Query: 65 TRDAILQL-RRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFATSGV 123
T DA +++ R +G R L+ G+ L+ A+ F Y+ L L + V
Sbjct: 99 TMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMV 158
Query: 124 AAVLAGT-TEAIFTPLERVQTLLQDHKHHDKFTNTYQAFK-ALKCHGIGEYYRGLVPILF 181
A LA T + +PLE ++T LQ H + + A+ G + G P
Sbjct: 159 AGALARLGTVTVISPLELMRTKLQ--AQHVSYRELGACVRTAVAQGGWRSLWLGWGPTAL 216
Query: 182 RNGLSNVLFFGLRGPIKEHLPTATTHSAHLVN-DFICGGLLGAMLGFLFFPINVVKTRIQ 240
R+ + L++ +K L V F+ GG+ G + L P +VVKT+ Q
Sbjct: 217 RDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQ 276
Query: 241 SQIGG--EFQSFPKVFQKIWL-----ERDRKLINLFRGAHLNYHRSLISWGIINATYEF 292
+G + P WL + LF G ++ S I+ +TYEF
Sbjct: 277 VALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEF 335
>gi|219555665 solute carrier family 25, member 39 isoform a [Homo
sapiens]
Length = 359
Score = 47.4 bits (111), Expect = 2e-05
Identities = 59/239 (24%), Positives = 94/239 (39%), Gaps = 13/239 (5%)
Query: 65 TRDAILQL-RRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFATSGV 123
T DA +++ R +G R L+ G+ L+ A+ F Y+ L L + V
Sbjct: 107 TMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMV 166
Query: 124 AAVLAGT-TEAIFTPLERVQTLLQDHKHHDKFTNTYQAFK-ALKCHGIGEYYRGLVPILF 181
A LA T + +PLE ++T LQ H + + A+ G + G P
Sbjct: 167 AGALARLGTVTVISPLELMRTKLQ--AQHVSYRELGACVRTAVAQGGWRSLWLGWGPTAL 224
Query: 182 RNGLSNVLFFGLRGPIKEHLPTATTHSAHLVN-DFICGGLLGAMLGFLFFPINVVKTRIQ 240
R+ + L++ +K L V F+ GG+ G + L P +VVKT+ Q
Sbjct: 225 RDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQ 284
Query: 241 SQIGG--EFQSFPKVFQKIWL-----ERDRKLINLFRGAHLNYHRSLISWGIINATYEF 292
+G + P WL + LF G ++ S I+ +TYEF
Sbjct: 285 VALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEF 343
>gi|21361114 solute carrier family 25 (mitochondrial carrier;
oxoglutarate carrier), member 11 [Homo sapiens]
Length = 314
Score = 47.4 bits (111), Expect = 2e-05
Identities = 54/225 (24%), Positives = 88/225 (39%), Gaps = 17/225 (7%)
Query: 34 YLCGCCAAFNNVAITFPIQKVLFRQQLYG--IKTRDAILQ-------LRRDGFRNLYRGI 84
+L G A P+ V R QL G KTR+ L+ +G R +Y G+
Sbjct: 25 FLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYTGL 84
Query: 85 LPPLMQKTTTLALMFGLYEDL-SCLLHKHVSAPEFATSGVAAVLAGTTEA-IFTPLE--R 140
L+++ T G+Y L L + P F V + AG T A + TP E
Sbjct: 85 SAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTPAEVAL 144
Query: 141 VQTLLQDHKHHDKFTNTYQAFKAL----KCHGIGEYYRGLVPILFRNGLSNVLFFGLRGP 196
++ D+ F AL + G+ +RG +P + R + N
Sbjct: 145 IRMTADGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYSQ 204
Query: 197 IKEHLPTATTHSAHLVNDFICGGLLGAMLGFLFFPINVVKTRIQS 241
K+ L + S +++ F + G + P+++ KTRIQ+
Sbjct: 205 SKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQN 249
>gi|41462412 solute carrier family 25, member 35 [Homo sapiens]
Length = 295
Score = 47.0 bits (110), Expect = 2e-05
Identities = 55/182 (30%), Positives = 80/182 (43%), Gaps = 40/182 (21%)
Query: 117 EFATSGVAAVLAGTTEAIFT-PLERVQTLLQ---------DHKHHDKFTNTYQAFKAL-K 165
+F SG+AA A +FT PLE V+T +Q ++ H + N + AF + K
Sbjct: 2 DFLMSGLAACGA----CVFTNPLEVVKTRMQLQGELQAPGTYQRH--YRNVFHAFITIGK 55
Query: 166 CHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKE--HLPTAT-THSAHLVNDFICGGLLG 222
G+ +GL P L L N + G G + +L TA THS G + G
Sbjct: 56 VDGLAALQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSP--ARSAAAGAMAG 113
Query: 223 AMLGFLFFPINVVKTRIQSQIGGE------------FQSFPKVFQKIWLERDRKLINLFR 270
M +L PI +VKT +Q+Q E FQ+ ++ QK L+ L+R
Sbjct: 114 VMGAYLGSPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQK------HGLVGLWR 167
Query: 271 GA 272
GA
Sbjct: 168 GA 169
>gi|157388991 solute carrier family 25, member 36 isoform b [Homo
sapiens]
Length = 310
Score = 46.6 bits (109), Expect = 3e-05
Identities = 60/244 (24%), Positives = 115/244 (47%), Gaps = 25/244 (10%)
Query: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGTT 131
L ++G R+L+RG+ P L+ + A+ F Y + L+ ++A +AG T
Sbjct: 72 LEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFT 131
Query: 132 EAIFT-PLERVQTLLQ--DHKHHDKFTNTYQAF-KALKCHGIGEYYRGLVPILFRNGLSN 187
T P+ ++T LQ ++ ++ K + G+ +YRG+ +
Sbjct: 132 AITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGM-SASYAGISET 190
Query: 188 VLFFGLRGPIKEHL---PTATT-----HSAHLVNDFICGGLLGAMLG-----FLFFPINV 234
V+ F + IK+ L TA+T S +DF+ G +L A + +P +V
Sbjct: 191 VIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFV-GMMLAAATSKTCATTIAYP-HV 248
Query: 235 VKTRIQSQIGGEFQSFPKVFQKI-WLERDRKLINLFRGAHLNYHRSLISWGIINATYEFL 293
V+TR++ + G +++SF FQ + L ++ +L+RG + R + + I+ ATYE +
Sbjct: 249 VRTRLREE-GTKYRSF---FQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELV 304
Query: 294 LKVI 297
+ ++
Sbjct: 305 VYLL 308
Score = 28.5 bits (62), Expect = 7.4
Identities = 13/41 (31%), Positives = 25/41 (60%)
Query: 70 LQLRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLH 110
L ++ +G+ +LYRG+ L+++ A+M YE + LL+
Sbjct: 269 LLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLN 309
Score = 28.1 bits (61), Expect = 9.7
Identities = 14/25 (56%), Positives = 18/25 (72%), Gaps = 3/25 (12%)
Query: 217 CGGLLGAMLGFLFFPINVVKTRIQS 241
CGG +GA+L P+ VVKTR+QS
Sbjct: 15 CGGTVGAILTC---PLEVVKTRLQS 36
>gi|108860679 solute carrier family 25, member 27 [Homo sapiens]
Length = 323
Score = 46.6 bits (109), Expect = 3e-05
Identities = 58/242 (23%), Positives = 98/242 (40%), Gaps = 35/242 (14%)
Query: 32 KHYLCGCCAAFNNVAITFPIQKVLFRQQLYGIKT------------------RDAILQLR 73
K L GC A +A TFP+ R Q+ G R A+ +
Sbjct: 22 KFLLSGCAATVAELA-TFPLDLTKTRLQMQGEAALARLGDGARESAPYRGMVRTALGIIE 80
Query: 74 RDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLL-----HKHVSAPEFATSGVAAVLA 128
+GF L++G+ P + + YE L ++ +H + G+ A +
Sbjct: 81 EEGFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVVFGKSEDEHYPLWKSVIGGMMAGVI 140
Query: 129 GTTEAIFTPLERVQTLLQDHKHHD----KFTNTYQAF-KALKCHGIGEYYRGLVPILFRN 183
G A T L +VQ ++ + + +F + AF K L GI + G VP + R
Sbjct: 141 GQFLANPTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKILAEGGIRGLWAGWVPNIQRA 200
Query: 184 GLSNVLFFGLRGPIKEHLPTATTHSAHLVN---DFICGGLLGAMLGFLFFPINVVKTRIQ 240
L N+ +K +L T +++ +C GL+ ++LG P +V+K+RI
Sbjct: 201 ALVNMGDLTTYDTVKHYLVLNTPLEDNIMTHGLSSLCSGLVASILG---TPADVIKSRIM 257
Query: 241 SQ 242
+Q
Sbjct: 258 NQ 259
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 46.6 bits (109), Expect = 3e-05
Identities = 67/273 (24%), Positives = 112/273 (41%), Gaps = 31/273 (11%)
Query: 48 TFPIQKVLFRQQLYG---------IKTRDAILQLRR----DGFRNLYRGILPPLMQKTTT 94
TFP+ R Q+ G IK R L R +G LY GI P L+++ +
Sbjct: 58 TFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASY 117
Query: 95 LALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGT-TEAIFTPLERVQTLLQDHKHHDK 153
+ G+Y+ L L + + + + V++G + I P + ++ +Q +
Sbjct: 118 GTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQ 177
Query: 154 FTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHL----PTATTHSA 209
+ + G +RG+VP R + + + K+HL T
Sbjct: 178 GSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILT 237
Query: 210 HLVNDFICGGLLGAMLGFLFFPINVVKTRIQSQ--IGGEFQSFPKVFQ---KIWLERDRK 264
H V+ F C GL GA+ P++VV+TR+ +Q I G + K+W +
Sbjct: 238 HFVSSFTC-GLAGALAS---NPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMW--KHEG 291
Query: 265 LINLFRGAHLNYHRSLISWGII-NATYEFLLKV 296
L++G N+ R L W II TYE L ++
Sbjct: 292 FFALYKGFWPNWLR-LGPWNIIFFITYEQLKRL 323
Score = 28.9 bits (63), Expect = 5.7
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Query: 203 TATTHSAHLVN--DFICGGLLGAMLGFLFFPINVVKTRIQSQ 242
T +H +N F+ GGL + F FP+++ KTR+Q Q
Sbjct: 30 TTVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQ 71
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 46.6 bits (109), Expect = 3e-05
Identities = 67/273 (24%), Positives = 112/273 (41%), Gaps = 31/273 (11%)
Query: 48 TFPIQKVLFRQQLYG---------IKTRDAILQLRR----DGFRNLYRGILPPLMQKTTT 94
TFP+ R Q+ G IK R L R +G LY GI P L+++ +
Sbjct: 55 TFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASY 114
Query: 95 LALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGT-TEAIFTPLERVQTLLQDHKHHDK 153
+ G+Y+ L L + + + + V++G + I P + ++ +Q +
Sbjct: 115 GTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQ 174
Query: 154 FTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHL----PTATTHSA 209
+ + G +RG+VP R + + + K+HL T
Sbjct: 175 GSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILT 234
Query: 210 HLVNDFICGGLLGAMLGFLFFPINVVKTRIQSQ--IGGEFQSFPKVFQ---KIWLERDRK 264
H V+ F C GL GA+ P++VV+TR+ +Q I G + K+W +
Sbjct: 235 HFVSSFTC-GLAGALAS---NPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMW--KHEG 288
Query: 265 LINLFRGAHLNYHRSLISWGII-NATYEFLLKV 296
L++G N+ R L W II TYE L ++
Sbjct: 289 FFALYKGFWPNWLR-LGPWNIIFFITYEQLKRL 320
Score = 28.9 bits (63), Expect = 5.7
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Query: 203 TATTHSAHLVN--DFICGGLLGAMLGFLFFPINVVKTRIQSQ 242
T +H +N F+ GGL + F FP+++ KTR+Q Q
Sbjct: 27 TTVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQ 68
>gi|13899342 solute carrier [Homo sapiens]
Length = 315
Score = 46.6 bits (109), Expect = 3e-05
Identities = 57/260 (21%), Positives = 97/260 (37%), Gaps = 36/260 (13%)
Query: 37 GCCAAFNNVAITFPIQKVLFRQQLYGIKTR-----DAILQLRR-DGFRNLYRGILPPLMQ 90
G A V FPI R Q K D +++ R +GF +YRG L
Sbjct: 15 GGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRGAAVNLTL 74
Query: 91 KTTTLALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGTTEAIFT-PLERVQTLLQDHK 149
T A+ + LL + +A AG + + T P+E ++ LQD
Sbjct: 75 VTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLKIQLQDAG 134
Query: 150 H-------------------------HDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNG 184
H + + T A++ L+ G+ YRGL L R+
Sbjct: 135 RLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGATLLRDI 194
Query: 185 LSNVLFFGLRGPIKEHLPTATTHSAHLVNDFICGGLLGAMLGFLFFPINVVKTRIQSQIG 244
++++F L + A + F+ G + G++ P++V+KTRIQ+
Sbjct: 195 PFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKK 254
Query: 245 G----EFQSFPKVFQKIWLE 260
G + +K+W++
Sbjct: 255 GLGEDMYSGITDCARKLWIQ 274
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 45.1 bits (105), Expect = 8e-05
Identities = 61/280 (21%), Positives = 112/280 (40%), Gaps = 25/280 (8%)
Query: 32 KHYLCGCCAAFNNVAITFPIQKVLFRQQLYGIKTRDAIL------QLRRDGFRNLYRGIL 85
+H + G A + T P+ ++ Q++ ++ + + +R G R+L+RG
Sbjct: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 247
Query: 86 PPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGT-TEAIFTPLERVQTL 144
+++ A+ F YE + L+ VA LAG ++ P+E ++T
Sbjct: 248 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 307
Query: 145 LQDHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHLPTA 204
+ K A + L G+ +Y+G VP N L + + G+ + E L A
Sbjct: 308 MALRKTGQYSGMLDCARRILAREGVAAFYKGYVP----NMLGIIPYAGIDLAVYETLKNA 363
Query: 205 TTHSAHLVND--------FICGGLLGAMLGFLFFPINVVKTRIQSQI---GGEFQSFPKV 253
+ VN CG + +P+ +V+TR+Q+Q G + +
Sbjct: 364 WLQH-YAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSL 422
Query: 254 FQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFL 293
F+ I R L+RG N+ + + + I YE L
Sbjct: 423 FKHIL--RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENL 460
Score = 29.3 bits (64), Expect = 4.4
Identities = 13/38 (34%), Positives = 22/38 (57%)
Query: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLL 109
LR +G LYRG+ P M+ +++ + +YE+L L
Sbjct: 427 LRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 464
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 45.1 bits (105), Expect = 8e-05
Identities = 61/280 (21%), Positives = 112/280 (40%), Gaps = 25/280 (8%)
Query: 32 KHYLCGCCAAFNNVAITFPIQKVLFRQQLYGIKTRDAIL------QLRRDGFRNLYRGIL 85
+H + G A + T P+ ++ Q++ ++ + + +R G R+L+RG
Sbjct: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 281
Query: 86 PPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGT-TEAIFTPLERVQTL 144
+++ A+ F YE + L+ VA LAG ++ P+E ++T
Sbjct: 282 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 341
Query: 145 LQDHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHLPTA 204
+ K A + L G+ +Y+G VP N L + + G+ + E L A
Sbjct: 342 MALRKTGQYSGMLDCARRILAREGVAAFYKGYVP----NMLGIIPYAGIDLAVYETLKNA 397
Query: 205 TTHSAHLVND--------FICGGLLGAMLGFLFFPINVVKTRIQSQI---GGEFQSFPKV 253
+ VN CG + +P+ +V+TR+Q+Q G + +
Sbjct: 398 WLQH-YAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSL 456
Query: 254 FQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFL 293
F+ I R L+RG N+ + + + I YE L
Sbjct: 457 FKHIL--RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENL 494
Score = 29.3 bits (64), Expect = 4.4
Identities = 13/38 (34%), Positives = 22/38 (57%)
Query: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLL 109
LR +G LYRG+ P M+ +++ + +YE+L L
Sbjct: 461 LRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 498
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 45.1 bits (105), Expect = 8e-05
Identities = 61/280 (21%), Positives = 112/280 (40%), Gaps = 25/280 (8%)
Query: 32 KHYLCGCCAAFNNVAITFPIQKVLFRQQLYGIKTRDAIL------QLRRDGFRNLYRGIL 85
+H + G A + T P+ ++ Q++ ++ + + +R G R+L+RG
Sbjct: 208 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 267
Query: 86 PPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGT-TEAIFTPLERVQTL 144
+++ A+ F YE + L+ VA LAG ++ P+E ++T
Sbjct: 268 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 327
Query: 145 LQDHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHLPTA 204
+ K A + L G+ +Y+G VP N L + + G+ + E L A
Sbjct: 328 MALRKTGQYSGMLDCARRILAREGVAAFYKGYVP----NMLGIIPYAGIDLAVYETLKNA 383
Query: 205 TTHSAHLVND--------FICGGLLGAMLGFLFFPINVVKTRIQSQI---GGEFQSFPKV 253
+ VN CG + +P+ +V+TR+Q+Q G + +
Sbjct: 384 WLQH-YAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSL 442
Query: 254 FQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFL 293
F+ I R L+RG N+ + + + I YE L
Sbjct: 443 FKHIL--RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENL 480
Score = 29.3 bits (64), Expect = 4.4
Identities = 13/38 (34%), Positives = 22/38 (57%)
Query: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLL 109
LR +G LYRG+ P M+ +++ + +YE+L L
Sbjct: 447 LRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 484
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 45.1 bits (105), Expect = 8e-05
Identities = 61/280 (21%), Positives = 112/280 (40%), Gaps = 25/280 (8%)
Query: 32 KHYLCGCCAAFNNVAITFPIQKVLFRQQLYGIKTRDAIL------QLRRDGFRNLYRGIL 85
+H + G A + T P+ ++ Q++ ++ + + +R G R+L+RG
Sbjct: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 247
Query: 86 PPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGT-TEAIFTPLERVQTL 144
+++ A+ F YE + L+ VA LAG ++ P+E ++T
Sbjct: 248 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 307
Query: 145 LQDHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHLPTA 204
+ K A + L G+ +Y+G VP N L + + G+ + E L A
Sbjct: 308 MALRKTGQYSGMLDCARRILAREGVAAFYKGYVP----NMLGIIPYAGIDLAVYETLKNA 363
Query: 205 TTHSAHLVND--------FICGGLLGAMLGFLFFPINVVKTRIQSQI---GGEFQSFPKV 253
+ VN CG + +P+ +V+TR+Q+Q G + +
Sbjct: 364 WLQH-YAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSL 422
Query: 254 FQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFL 293
F+ I R L+RG N+ + + + I YE L
Sbjct: 423 FKHIL--RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENL 460
Score = 29.3 bits (64), Expect = 4.4
Identities = 13/38 (34%), Positives = 22/38 (57%)
Query: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLL 109
LR +G LYRG+ P M+ +++ + +YE+L L
Sbjct: 427 LRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 464
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.142 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,773,923
Number of Sequences: 37866
Number of extensions: 432815
Number of successful extensions: 1348
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 1133
Number of HSP's gapped (non-prelim): 172
length of query: 297
length of database: 18,247,518
effective HSP length: 102
effective length of query: 195
effective length of database: 14,385,186
effective search space: 2805111270
effective search space used: 2805111270
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.